This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.

Formulated by members of the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN), Functional Imaging in Nephro-urology is not a textbook on uronephrology or radionuclides in nephro-urology, or even a book on new techniques in imaging. What the editor and authors provide here is a unique opportunity to evaluate the strategic management techniques (both diagnosis and follow-up) of a number of uronephrological entities.
Demonstrating the experience of the authors in using various imaging modalities, and detailing the benefits and controversies which are associated with their clinical applications, this text presents management strategies based on the patient, the choice of modality, and cost implications.
Detailed, well-referenced and highly illustrated, this is an important book for radiologists, nephrologists and urologists working with children and adults, specialists in renal nuclear medicine, and pediatricians.

The 2005 bicentenary of Hans Christian Andersen's birth is an opportunity to re-evaluate the achievement of one of the great figures of the fairy tale and storytelling tradition, a beloved writer famous for The Snow Queen and The Little Mermaid, The Ugly Duckling and The Red Shoes and many other now classic tales. Jack Zipes broadens our understanding of Andersen by exploring the relation of the Danish writer's work to the development of literature and of the fairy tale in particular. Based on thirty-five years of researching and writing on Andersen, this new book is a welcome reconsideration of Andersen's place and of his reception in English-speaking countries and on film.

This authoritative reference reviews current and emerging molecular imaging modalities that are expected to impact the detection and treatment of lung diseases in the near future-including applications in gene expression and inflammation imaging; the imaging of pulmonary cytokine regulation; the molecular imaging of angiogenesis, the airways, and lung cancer; and the imaging of cellular death and cell trafficking.

Many topics have inspired significant amounts of neuroimaging research in recent years, and the study of mental imagery was one of the earliest to receive a thorough empirical investigation. Twenty years later, the goal of understanding this pervasive but elusive phenomenon continues to motivate a number of sustained research programs on the part of cognitive psychologists and neuroscientists. The issues at stake are easy to formulate, even if the answers sometimes may be difficult to obtain: Which parts of the human brain are active when a person generates a memory image of an absent object? To what extent does mental imagery activate cortical structures known to subserve perceptual visual experience? If imagery and like-modality perception produce similar patterns of brain activation, what sorts of theories should cognitive scientists develop about the underlying mechanisms? How can we best understand why people differ in their imagery abilities? These are questions to which the contributors to the special issue "Neuroimaging of Mental Imagery" offer answers, through seven original studies based on the use of modern neuroimaging techniques, primarily positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). These techniques are used in the context of a variety of cognitive tasks involving memory, problem solving, and other processes. Unlike most research in psychology, much of the work reported here explicitly addresses individual differences, which must be considered carefully in order to provide comprehensive accounts of the results of imagery experiments. Although these investigations were planned and carried out independently, we find a remarkable convergence among them. And this may be the surest sign that a field is indeed moving forward.

A companion to the Insight Toolkit An introduction to the theory of modern medical image processing, including the analysis of data from - X-ray computer tomography, - magnetic resonance imaging, - nuclear medicine, - and ultrasound. Using an algorithmic approach, and providing the mathematical, statistical, or signal processing as needed for background, the authors describe the principles of all methods implemented in the Insight Toolkit (ITK), a freely available, open- source, object-oriented library. The emphasis is on providing intuitive descriptions of the principles and illustrative examples of results from the leading filtering, segmentation, and registration methods. This book covers the mathematical foundations of important techniques such as: - Statistical pattern recognition, - PDE-based nonlinear image filtering, - Markov random fields, - Level set methods, - Deformable models, - Mutual information, image-based registration - Non-rigid image data fusion With contributions from: Elsa Angelini, Brian Avants, Stephen Aylward, Ting Chen, Jeffrey Duda, Jim Gee, Luis Ibanez, Celina Imielinska, Yinpeng Jin, Jisung Kim, Bill Lorensen, Dimitris Metaxas, Lydia Ng, Punam Saha, George Stetten, Tessa Sundaram, Jay Udupa, Ross Whitaker, Terry Yoo, and Ying Zhuge. The Insight Toolkit is part of the Visible Human Project from the National Library of Medicine, with support from NIDCR, NINDS, NIMH, NEI, NSF, TATRC, NCI, and NIDCD.

Informatics in Medical Imaging provides a comprehensive survey of the field of medical imaging informatics. In addition to radiology, it also addresses other specialties such as pathology, cardiology, dermatology, and surgery, which have adopted the use of digital images. The book discusses basic imaging informatics protocols, picture archiving and communication systems, and the electronic medical record. It details key instrumentation and data mining technologies used in medical imaging informatics as well as practical operational issues, such as procurement, maintenance, teleradiology, and ethics. Highlights Introduces the basic ideas of imaging informatics, the terms used, and how data are represented and transmitted Emphasizes the fundamental communication paradigms: HL7, DICOM, and IHE Describes information systems that are typically used within imaging departments: orders and result systems, acquisition systems, reporting systems, archives, and information-display systems Outlines the principal components of modern computing, networks, and storage systems Covers the technology and principles of display and acquisition detectors, and rounds out with a discussion of other key computer technologies Discusses procurement and maintenance issues; ethics and its relationship to government initiatives like HIPAA; and constructs beyond radiology The technologies of medical imaging and radiation therapy are so complex and computer-driven that it is difficult for physicians and technologists responsible for their clinical use to know exactly what is happening at the point of care. Medical physicists are best equipped to understand the technologies and their applications, and these individuals are assuming greater responsibilities in the clinical arena to ensure that intended care is delivered in a safe and effective manner. Built on a foundation of classic and cutting-edge research, Informatics in Medical Imaging supports and updates medical physicists functioning at the intersection of radiology and radiation.

This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completelyimpossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology inthe broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, "Make Life Visible" sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.

This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.

With a focus on how to perform and effectively interpret pelvic ultrasound exams, Pelvic Ultrasound Imaging: A Cased-Based Application offers a unique learning experience that is ideal for ob/gyn and radiology practitioners and residents, urogynecology practitioners and fellows, diagnostic medical sonographers and those who are studying for Board exams. Current cases in gynecology and urogynecology are presented in a step-by-step format based on resident and fellow one-on-one didactic oral case reviews. An expert walk-through for each case's imaging set includes directive questions to help the reader perform proper exam assessment. This workbook: Presents cases in the way a clinical day unfolds, varied and unrelated to the previous case. Cases get progressively harder, increasingly challenging the reader's interpretation skills while moving through the text. Provides step-by-step instruction throughout, including development of 3D volume set skills, reporting nomenclature, discussion of diagnostic criteria, instrumentation topics, and clinical correlation. Highlights the importance of critically assessing, not merely diagnosing based on a presumed classic image appearance for the most common pathologies. Includes examples of common gynecology cases such as ovarian corpus luteum, hemorrhagic corpus luteum, uterine leiomyomata, endometrial polyps, and caesarean section scars, as well as more uncommon cases. Includes examples of common pelvic floor cases such as normal anal sphincter complex and thickened bladder wall, as well as more uncommon urogynecology pathologies such as rectal vaginal fistula, rectal prolapse, and mesh assessment. Walks the reader through each case with directive questions to improve diagnostic appraisal. Includes up to five images per case along with exam findings and brief clinical correlations. Provides videos on Elsevier eBooks for Practicing Clinicians that illustrate typically encountered real-time dynamic changes. Enhanced eBook version included with purchase. Your enhanced eBook allows you access to all of the text, figures, reporting templates, and references from the book on a variety of devices.

Comprised of chapters carefully selected from CRC's best-selling engineering handbooks, volumes in the Principles and Applications in Engineering series provide convenient, economical references sharply focused on particular engineering topics and subspecialties. Culled from the Biomedical Engineering Handbook, Biomedical Imaging provides an overview of the main medical imaging devices and highlights emerging systems. With applications ranging from imaging the whole body to replicating cellular components, the imaging modalities discussed include x-ray systems, computed tomographic systems, magnetic resonance imaging, nuclear medicine, ultrasound, MR microscopy, virtual reality, and more.

Now in its fourth edition, this book presents a complete course in electrocardiography (ECG) for students and a reference for advanced trainees and technicians. The author's step-by-step approach lets readers focus only on needed information and proceed at their own pace. Brief and to the point, the text explains how an electrocardiograph works, how to draw a hexaxial system, plot vectors, produce a good ECG tracing, and how to draw a spatial vector. Advanced material is clearly marked, allowing students to work through the complete text with just enough theory to understand the facts and providing advanced trainees with a review and foundation for further study.

The leading reference book in the field of electrodiagnostic medicine just got better with this remarkable new edition, which is thoroughly revised and updated. Written by three of the leading authorities in the field along with several expert contributors, this comprehensive textbook continues to provide the fundamentals as well as the practical, clinical applications of electrodiagnostic medicine for novices and experienced practitioners alike. The text is complemented by a superb CD-ROM containing videos of waveforms The text is clear and concise, and enhanced by hundreds of illustrations and tables. "The best single reference book currently available in the field." - Excerpt from a review of the first edition of this book from the New England Journal of Medicine New chapters include Heriditary Neuropathies, Quantitative Sensory Testing, and Chemical Denervation All chapters from previous edition were extensively reworked and several topics (myopathies, polyneuropathies) were expanded to generate multiple chapters

Radioembolization is a widely used treatment for non-resectable primary and secondary liver cancer. This handbook addresses the radiation biology, physics, nuclear medicine, and imaging for radioembolization using Yttrium-90 (90Y) microspheres, in addition to discussing aspects related to interventional radiology. The contents reflect on and off-label treatment indications, dose-response relationships, treatment-planning, therapy optimization, radiation safety, imaging follow-up and many other facets of this therapy necessary for both novice and advanced users alike.

Magnetic resonance imaging (MRI) is a technique used in biomedical imaging and radiology to visualize internal structures of the body. Because MRI provides excellent contrast between different soft tissues, the technique is especially useful for diagnostic imaging of the brain, muscles, and heart. In the past 20 years, MRI technology has improved significantly with the introduction of systems up to 7 Tesla (7 T) and with the development of numerous post-processing algorithms such as diffusion tensor imaging (DTI), functional MRI (fMRI), and spectroscopic imaging. From these developments, the diagnostic potentialities of MRI have improved impressively with an exceptional spatial resolution and the possibility of analyzing the morphology and function of several kinds of pathology. Given these exciting developments, the Magnetic Resonance Imaging Handbook: Imaging of the Pelvis, Musculoskeletal System, and Special Applications to CAD is a timely addition to the growing body of literature in the field. Offering comprehensive coverage of cutting-edge imaging modalities, this book: Discusses MRI of the urinary system, pelvis, spine, soft tissues, lymphatics, and brain Explains how MRI can be used in fetal, pediatric, forensic, postmortem, and computer-aided diagnostic (CAD) applications Highlights each organ's anatomy and pathological processes with high-quality images Examines the protocols and potentialities of advanced MRI scanners such as 7 T systems Includes extensive references at the end of each chapter to enhance further study Thus, the Magnetic Resonance Imaging Handbook: Imaging of the Pelvis, Musculoskeletal System, and Special Applications to CAD provides radiologists and imaging specialists with a valuable, state-of-the-art reference on MRI.

Choice Recommended Title, January 2021 This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective

Designed not only to give you the facts, but to help you understand and remember them, Learning Electrocardiography: A Complete Course, Fourth Edition is a learning tool for students and a reference for advanced trainees and technicians. The author's step-by-step teaching method lets you focus on the information as you need it and proceed at your own pace. He combines twenty years of teaching experience with the latest information on new methods and uses of electrocardiography. Brief and to the point, the text explains how an electrocardiograph works, how to draw a hexaxial system, plot vectors, produce a good ECG tracing, and draw a spatial vector. You will learn how to produce a technically good electrocardiograph, perform an office exercise test without a treadmill, and recognize the presence of chronic obstructive pulmonary disease without the necessity of diagnosing right ventricular hypertrophy. Providing a logical, clear, and complete approach to the subject, Learning Electrocardiography: A Complete Course, Fourth Edition is the resource to use when learning or reviewing electrocardiography.

This book covers state-of-the-art medical image analysis approaches currently pursued in autism research. Chapters cover recent advances in diagnosis using structural neuroimaging. All aspects of imaging are included, such as electrophysiology (EEG, ERP, QEEG, and MEG), postmortem techniques, and advantages and difficulties of depositing/acquiring images in larger databases. The book incorporates 2D, 3D, and 4D imaging and advances scientific research within the broad field of autism imaging.

Vortex Formation in the Cardiovascular System will recapitulate the current knowledge about the vortex formation in the cardiovascular system, from mechanics to cardiology. This can facilitate the interaction between basic scientists and clinicians on the topic of the circulatory system. The book begins with a synopsis of the fundamentals aspects of fluid mechanics to give the reader the essential background to address the proceeding chapters. Then the fundamental elements of vortex dynamics will be discussed, explaining the conditions for their formation and the rules governing their dynamics. The main equations are accompanied by mathematical models. Cardiovascular vortex formation is first analyzed in physiological, healthy conditions in the heart chambers and in the large arterial vessels. The analysis is initially presented with an intuitive appeal grounded on the physical phenomena and a focus on its clinical significance.In the proceeding chapters, the knowledge gained from either clinical or basic science literature will be discussed. The corresponding mathematical elements will finally be presented to ensure the adequate diligence. The proceeding chapters ensue to the analysis of pathological conditions, when the reader may have developed the ability to recognize normal from abnormal vortex formation phenomenon. Pathological vortex formation represents vortices that develop at sites where normally laminar flow should exist, e.g. stenosis and aneurisms. This analysis naturally leads to the interaction of vortices due to the surgical procedures with respect to prediction of changes in vortex formation. The existing techniques, from medical imaging to numerical simulations, to explore vortex flows in the cardiovascular systems will also be described. The presentations are accompanied by the mathematical definitions can that be understandable for reader without the advanced mathematical background, while an interested reader with more advanced knowledge in mathematics can be referred to references for further quantitative analyses. The book pursues the objective to transfer the fundamental vortex formation phenomena with application to the cardiovascular system to the reader. This book will be a valuable support for physicians in the evaluation of vortex influence on diagnosis and therapeutic choices. At the same time, the book will provide the rigorous information for research scientists, either from medicine and mechanics, working on the cardiovascular circulation incurring with the physics of vortex dynamics.

Clinical conformal radiotherapy is the holy grail of radiation treatment and is now becoming a reality through the combined efforts of physical scientists and engineers, who have improved the physical basis of radiotherapy, and the interest and concern of imaginative radiotherapists and radiographers. Intensity-Modulated Radiation Therapy describes in detail the physics germane to the development of a particular form of clinical conformal radiotherapy called intensity modulated radiation therapy (IMRT). IMRT has become a topic of tremendous importance in recent years and is now being seriously investigated for its potential to improve the outcome of radiation therapy. The book collates the state-of-the-art literature together with the author's personal research experience and that of colleagues in the field to produce a text suitable for new research workers, Ph.D. students, and practicing radiation physicists that require a thorough introduction to IMRT. Fully illustrated, indexed, and referenced, the book has been prepared in a form suitable for supporting a teaching course.

Formulated by members of the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN), Functional Imaging in Nephro-urology is not a textbook on uronephrology or radionuclides in nephro-urology, or even a book on new techniques in imaging. What the editor and authors provide here is a unique opportunity to evaluate the strategic management techniques (both diagnosis and follow-up) of a number of uronephrological entities. Demonstrating the experience of the authors in using various imaging modalities, and detailing the benefits and controversies which are associated with their clinical applications, this text presents management strategies based on the patient, the choice of modality, and cost implications. Detailed, well-referenced and highly illustrated, this is an important book for radiologists, nephrologists and urologists working with children and adults, specialists in renal nuclear medicine, and pediatricians.

Automatic image analysis has become an important tool in many fields of biology, medicine, and other sciences. Since the first edition of Image Analysis: Methods and Applications, the development of both software and hardware technology has undergone quantum leaps. For example, specific mathematical filters have been developed for quality enhancement of original images and for extraction of specific features of interest. Also, more complex programs have been developed for the analysis of object forms in distinguishing cancer cells from normal tissue cells. Just as significant, three-dimensional analysis of proteins, organelles, or macroscopic objects is even more complex. In addition, recent space-based experiments have optimized techniques for the extraction of movement parameters of numerous motile objects.

The second edition of Image Analysis: Methods and Applications addresses all these new developments. Moreover, two new chapters have been added. One focuses on images on the internet, and the other discusses microscope image restoration. These chapters add significantly to the existing body of information on Internet communication protocol and environment as well as to that on image file formats considerations. The materials also include a list of internet Web sites that pertain to digital images and software along with those that relate to image processing.

With these considerations in mind, Image Analysis: Methods and Application, Second Edition is of incalculable value to professionals, academics, and users of all aspects of image analysis in biology and other areas of science.