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During the past two decades, there has been an increasing appreciation of the significant value that lifetime-based techniques can add to biomedical studies and applications of fluorescence. Bringing together perspectives of different research communities, Fluorescence Lifetime Spectroscopy and Imaging: Principles and Applications in Biomedical Diagnostics explores the remarkable advances in time-resolved fluorescence techniques and their role in a wide range of biological and clinical applications. Broadly accessible, the book captures the state-of-the-art of fluorescence lifetime metrology and imaging and provides current perspectives on their applications to biomedical studies of intact tissues and medical diagnosis. The text introduces these techniques within the wider context of fluorescence spectroscopy and describes basic principles underlying current instrumentation for fluorescence lifetime imaging and metrology (FLIM). It also covers the wide range of methods, including single channel (point) spectroscopy, fluorescence lifetime imaging microscopy, and single- and multi-photon excitation. Edited by pioneers in this field, with contributions from leading experts, the book includes an overview of complementary techniques that help researchers beginning FLIM research. It offers a comprehensive treatment of fundamental principles, instrumentation, analytical methods, and applications. It also provides an overview of the label-free contrast available from lifetime measurements of tissue autofluorescence and the prospects for exploiting this for clinical applications and biomedical research including drug discovery.
In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This well-illustrated two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including preclinical and clinical imaging techniques, based on US, CT, MRI, PET and hybrid modalities. This first volume explains the biophysical basis for these functional imaging techniques and describes the techniques themselves. Detailed information is provided on the imaging of cancer hallmarks, including angiogenesis, tumor metabolism, and hypoxia. The techniques and their roles are then discussed individually, covering the full range of modalities in clinical use as well as new molecular and functional techniques. The value of a multiparametric approach is also carefully considered.
Edited by and featuring contributions from world-class researchers, Ophthalmological Imaging and Applications offers a unified work of the latest human eye imaging and modeling techniques that have been proposed and applied to the diagnosis of ophthalmologic problems, including inflammation, cataracts, diabetic retinopathy, and glaucoma. With a focus on theory, basic principles, and results derived from research, the book: Explores various morphological, textural, higher-order spectral, and wavelet transformation techniques used to extract salient features from images of the human eye Examines 2D and 3D finite element and boundary element models of the human eye developed to simulate thermal steady-state conditions Addresses the difficult task of benchmarking the validity of human eye imaging techniques and computer-simulated results with experimental measurements Intended to be a companion to Image Analysis and Modeling in Ophthalmology, this volume covers several aspects of multimodal ophthalmological imaging and applications, presenting information in an accessible manner to appeal to a wide audience of students, researchers, and practitioners. Ophthalmological Imaging and Applications considers promising simulations that pave the way for new possibilities in computational methods for eye health care.
Interpret the complexities of neuroanatomy like never before with the unparalleled coverage and expert guidance from Drs. Srinivasan Mukundan and Thomas C. Lee in this outstanding volume of the Netter's Correlative Imaging series. Beautiful and instructive Netter paintings and illustrated cross-sections created in the Netter style are presented side by side high-quality patient images and key anatomic descriptions to help you envision and review intricate neuroanatomy. View the brain, spinal cord, and cranial nerves, as well as head and neck anatomy through modern imaging techniques in a variety of planes, complemented with a detailed illustration of each slice done in the instructional and aesthetic Netter style. Find anatomical landmarks quickly and easily through comprehensive labeling and concise text highlighting key points related to the illustration and image pairings. Correlate patient data to idealized normal anatomy, always in the same view with the same labeling system. Access NetterReference.com where you can quickly and simultaneously scroll through images and illustrations.
There are many modalities available to image the heart and this variety and number of scan types can prove to be daunting to radiologists and cardiologists. In addition, there are the numerous devices, stents, valves and other paraphernalia which are employed in the management of cardiac disease, which need to be recognised and identified when interpreting any of these various scans. Containing 75 challenging clinical cases and illustrated with superb, high quality images, Cardiac Imaging covers a wide range of cardiac imaging problems from basic radiographic cases to more challenging and esoteric cases involving echocardiography, cardiac MRI, cardiac CT and myocardial perfusion imaging. The book uses an accessible format for quick assimilation. It remains an invaluable text for all radiology and cardiology professionals in practice and in training, from hospital-based doctors preparing for higher examinations to established physicians in their continuing professional development.
More than 400 diagnoses that are delineated, referenced, and lavishly illustrated highlight the third edition of this bestselling reference. Award-winning educator Dr. Carl Merrow and his expert author team provide carefully updated information in a concise, bulleted format, keeping you current with recent advances in pediatric radiology. Succinct text, outstanding illustrations, and up-to-date content make this title a must-have reference for both general radiologists and pediatric imaging specialists who need a single, go-to guide in this fast-changing area. Concise, bulleted text provides efficient information on more than 400 diagnoses that are clearly illustrated with 2,500 superb images Meticulously updated throughout, with new diagnoses and hundreds of new images that provide the most current information in the field Expanded coverage of normal development and variations in childhood, including brain myelination, variant positions of important bowel anatomy, and bone marrow changes on MR Increased focus on the molecular/genetic basis of many diseases, including changes in current medical terminology as well as appearances by alternate modalities Expert guidance on new MR techniques for the evaluation of disease, including the use of newer contrast agents, acute and chronic pediatric musculoskeletal traumatic injuries often seen in young athletes, and congenital airway anomalies, such as CHAOS and tracheal agenesis New and revised classifications and staging systems of various pediatric disorders, including neoplasms, vascular anomalies, and childhood interstitial lung diseases (ChILD) Expert Consult eBook version included with purchase, which allows you to search all of the text, figures, images, and references from the book on a variety of devices
A new edition of the essential resource on using functional neuroimaging techniques to study the neural basis of cognition, revised with the student in mind; thoroughly updated, with new chapters on fMRI physics, skill learning, emotion and social cognition, and other topics. This essential resource on neuroimaging provides an accessible and user-friendly introduction to the field written by leading researchers. The book describes theoretical and methodological developments in the use of functional neuroimaging techniques to study the neural basis of cognition, from early scientific efforts to link brain and behavior to the latest applications of fMRI and PET methods. The core of the book covers fMRI and PET studies in specific domains: attention, skill learning, semantic memory, language, episodic memory, working memory, and executive functions. By introducing a technique within the description of a domain, the book offers a clear explanation of the process while highlighting its biological context. The emphasis on readability makes Handbook of Functional Neuroimaging of Cognition ideal for classroom use in advanced undergraduate and graduate courses in cognitive neuroscience. This second edition has been completely updated to reflect new developments in the field, with existing chapters rewritten and new chapters added to each section. The section on history and methods now includes a chapter on the crucial topic of the physics of functional neuroimaging; the chapters on skill learning and executive functions are new to the domain section; and chapters on childhood development and emotion and social cognition have been added to the section on developmental, social, and clinical applications. The color insert has been increased in size, enhancing the visual display of representative findings. Contributors Todd S. Braver, Jeffrey Browndyke, Roberto Cabeza, B.J. Casey, Jody Culham, Clayton E. Curtis, Mark D'Esposito, Sander Daselaar, Lila Davachi, Ian Dobbins, Karl J. Friston, Barry Giesbrecht, Todd C. Handy, Joseph B. Hopfinger, Scott A. Huettel, Irene P. Kan, Alan Kingstone, Eleni Kotsoni, Kevin S. LaBar, George R. Mangun, Gregory McCarthy, Uta Noppeney, Robyn T. Oliver, Elizabeth A. Phelps, Russel A. Poldrack, Cathy J. Price, Marcus E. Raichle, Hannes Ruge, Gaia Scerif, Allen W. Song, Sharon L. Thompson-Schill, Daniel T. Willingham, Richard J.S. Wise
The recent development of three-dimensional imaging techniques has provided an enormous amount of information relevant to the clinical management of patients at low and high risk for coronary artery disease. However, while progress in each individual technique has been rapid, the correlation of findings obtained with radiology, nuclear medicine, and magnetic resonance imaging is still relatively neglected. In this book, qualified experts in cardiac imaging present the basic concepts of cardiac pathology and imaging and compare the findings obtained in particular subspecialties with those acquired using other techniques. In this way the reader will learn how images and techniques can be integrated in clinical practice to the benefit of the patient. In addition, it is explained how appropriate multimodality integration can reduce the patient's exposure to ionizing radiation. Physicians ranging from cardiac surgeons to internal medicine specialists and even public health administrators will find this book invaluable in understanding the role of hybrid cardiac imaging.
Interstitial lung disease (ILD) refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It is a general category that covers many different lung conditions. Part of the Clinico Radiological Series, this book is a guide to diagnostic imaging of interstitial lung diseases for clinicians. Beginning with an overview of classification and terminology, and various imaging modalities, the following sections describe imaging techniques for many different lung disorders. A complete section is dedicated to paediatric lung diseases. The comprehensive text is highly illustrated with nearly 900 radiological images and tables. Also part of the Clinico Radiological Series, is Temporal Bone Imaging (9789385891908). Key Points Practical guide to diagnostic imaging of interstitial lung diseases Part of the Clinico Radiological Series Includes complete section on Paediatric lung diseases Highly illustrated with nearly 900 radiological images and tables
The content of this volume has been added to "eMagRes" (formerly "Encyclopedia of Magnetic Resonance)" - the ultimate online resource for NMR and MRI. Up to now MRI could not be used clinically for imaging fine structures of bones or muscles. Since the late 1990s however, the scene has changed dramatically. In particular, Graeme Bydder and his many collaborators have demonstrated the possibility - and importance - of imaging structures in the body that were previously regarded as being "MR Invisible." The images obtained with a variety of these newly developed methods exhibit complex contrast, resulting in a new quality of images for a wide range of new applications.
This Handbook is designed to enable the radiology community to begin their assessment of how best to exploit these new capabilities. It is organised in four major sections - the first of which, after an Introduction, deals with the basic science underlying the rest of the contents of the Handbook. The second, larger, section describes the techniques which are used in recovering the short T2 and T2* data from which the images are reconstructed. The third and fourth sections present a range of applications of the methods described earlier. The third section deals with pre-clinical uses and studies, while the final section describes a range of clinical applications. It is this last section that will surely have the biggest impact on the development in the next few years as the huge promise of Short T2 and T2* Imaging will be exploited to the benefit of patients.
In many instances, the authors of an article are the only research group who have published on the topic they describe. This demonstrates that this Handbook presents a range of methods and applications with a huge potential for future developments.
About "EMR Handbooks / eMagRes Handbooks"
The "Encyclopedia of Magnetic Resonance "(up to 2012) and" eMagRes "(from 2013 onward) publish a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of "EMR Handbooks / eMagRes Handbooks" on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of articles from "eMagRes." In consultation with the "eMagRes" Editorial Board, the "EMR Handbooks / eMagRes Handbooks" are coherently planned in advance by specially-selected Editors, and new articles are written (together with updates of some already existing articles) to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry.
Have the content of this Handbook and the complete content of "eMagRes "at your fingertips Visit: www.wileyonlinelibrary.com/ref/eMagResView other "eMagRes" publications here
To meet the demands of practicing radiologic technologist and students in training, Blackwell introduces the latest volume of the Rad Tech's Guide Series. "Rad Tech's Guide to Equipment Operation and Maintenance" promises a clinically-relevant introductory review of radiographic imaging systems. This condensed handbook is both a concise review for board preparation exams, as well as handy reference guide for the busy rad tech.
This on the spot reference features:
Computational Modelling of Objects Represented in Images: Fundamentals, Methods and Applications III contains all contributions presented at the International Symposium CompIMAGE 2012 - Computational Modelling of Object Presented in Images: Fundamentals, Methods and Applications (Rome, Italy, 5-7 September 2012). The contributions cover the state-of-art and new trends in the fields of: - 3D Vision; - Biometric Recognition; - Computational Bioimaging and Visualization; - Computer Vision in Robotics and Automation; - Data Acquisition, Interpolation, Registration and Compression; - Image Enhancement and Restoring; - Image Processing and Analysis; - Image Segmentation; - Medical Imaging; - Modeling and Simulation; - Motion and Deformation Analysis; - Remote Sensing; - Scientific Visualization Computational Modelling of Objects Represented in Images: Fundamentals, Methods and Applications III addresses different techniques, such as optimization methods, geometry, finite element method, principal component analysis, stochastic methods, neural networks and fuzzy logic. The book is useful to researchers and students with multidisciplinary interests related to Computational Vision, Computational Mechanics, Medicine, Engineering and Architecture.
The updated 4th Edition of Stephenson's Diagnostic Medical Sonography: Obstetrics and Gynecology offers the most in-depth, current, and consistent coverage of this crucial sonography topic available today. And is an intregal part of the Diagnostic Medical Sonography Series , which includes new editions of Diagnostic Medical Sonography: Abdomen and Superficial Structures, Diagnostic Medical Sonography: Obstetrics and Gynecology, and Diagnostic Medical Sonography: The Vascular System, provides the right content at the right level for the right way to teach and learn. New and updated images throughout each text help bring the visual field of sonography to life. Up-to-date coverage of diagnostic criteria in every text reflects today's best practices. Pathology boxes with tables of relevant pathologies are ideal for quick reference or review. Critical Thinking Questions in every chapter help students apply their knowledge to clinical situations and develop the analytical skills they'll need for a career in sonography. A complete Glossary defines important terminology to help students master the vocabulary of the profession. Updated references reflect the latest research in the field. eBook available for separate purchase. Faster, smarter, and more convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and much more. A hands-on workbook (available separately for each series title) provides a variety of custom-designed exercises to help students master each objective and get the most out of their study time.
The focus of this new book is for medicinal chemists on the chemical agents that have been used, or might be required in the future, and the methods of synthesis for inserting the reporter groups. Medicinal chemists need to know the critical issues involved in using such chemical agents with regard to the biological applications - for instance - what properties are needed chemically and why? The topics covered in the book are: PET, SPECT, contrast agents, radioimaging/radionuclide conjugates, receptor mapping, small animal imaging (eg. WBAR - whole body autoradiography); photoinduced labelling, as well as chapters on the physical techniques used including: NMR, mass spectrometry and Xray. A key reference for academics, postgraduates, researchers, industrialists and professionals working in or joining this field.
Titles in the Pocket Tutor series give practical guidance on subjects that medical students and foundation doctors need help with on the go, at a highly affordable price that puts them within reach of those rotating through modular courses or working on attachment. Highly structured, bite-size content helps novices combat the fear factor associated with day to day clinical training, and provides just enough for a new rotation. Key Features * Highly affordable price and convenient pocket size format - fits in back pocket * Logical, sequential content: the first principles of MSK imaging, then a guide to understanding a normal image and the building blocks of an abnormal image, before describing specific clinical disorders * Clinical disorders are illustrated by high quality radiographs, ultrasounds, CTs and MRIs, with brief accompanying text that clearly identifies the defining features of the image * Focuses on the conditions that medical students, junior doctors and trainees are most likely to see and be tested on.
MRI is a non-invasive and non-ionizing imaging modality that is perfectly suited for the diagnosis and follow-up of both pediatric and adult congenital heart disease. It provides a large field of view and has the unique ability to depict complex cardiac and vascular anatomy and to measure cardiac function and flow within one examination. MRI is the ideal complement to echocardiography whenever the information provided by the latter is limited. This book has been conceived as a self-teaching manual that will assist qualified radiologists, cardiologists, and pediatricians, as well as those in training. It is richly illustrated with numerous images and drawings that cover all usual and most unusual anomalies. The principal author, Professor Bruno Kastler, is head of radiology at Besancon University Hospital, France and is board certified in both radiology and cardiology.
A pragmatic, common sense approach to the detection, evaluation and management of breast diseases and related imaging findings! The fourth edition of this best selling "how-to" book includes major revisions, including the expansion of the screening mammography and breast MRI chapters, as well as the addition of digital breast tomosynthesis studies. Rather than having selected cropped images, the print and online versions of this book provide the reader with thousands of high quality images and complete imaging evaluations, from the screening images to the diagnostic mammogram, and-when appropriate-images from ultrasound, MRI, imaging guided biopsy, and preoperative wire localizations. Bulleted "key-facts" describe clinical, imaging and histological findings for a spectrum of breast diseases. With this book, breast-imaging radiologists are strongly encouraged to provide clinical, imaging and pathology concordance for optimal patient care, as well as direct and clinically relevant communication with providers and patients. Key Features: Picture yourself in front of a screening mammogram or breast MRI ... what now? How do you know if the study is interpretable? What are you looking for? Where do you look? If you detect something, what is the next appropriate step and how do you describe the finding? You will have access to hundreds of complete patient evaluations with thousands of images that include screening and diagnostic mammography, digital breast tomosynthesis, ultrasound, magnetic resonance studies and imaging guided breast related procedures with relevant pathology results and, when appropriate, the pathological stage. Develop appropriate differential considerations for the spectrum of breast imaging findings and appropriate management strategies. Review the indications for imaging guided procedures with step-by-step descriptions for each procedure illustrated with diagrams and images. Establish an optimal QA/QC program for your mammography practice, based on the concepts published by the ACR, regarding testing across digital platforms in the online version of the book. Test your knowledge and skills with a self-assessment chapter online. Your book purchase includes a complimentary download of the enhanced eBook for iOS, Android, PC & Mac.Take advantage of these practical features that will improve your eBook experience: The ability to download the eBook on multiple devices at one time - providing a seamless reading experience online or offline Powerful search tools and smart navigation cross-links that allow you to search within this book, or across your entire library of VitalSource eBooks Multiple viewing options that enable you to scale images and text to any size without losing page clarity as well as responsive design The ability to highlight text and add notes with one click
Spinal Imaging: Critical Topics for Clinical Practice is a concise review of commonly used MRI sequences for spinal imaging and new sequences related to the assessment of spinal CSF flow, with their clinical applications. The book is edited by Mauricio Castillo, Chief of the Division of Neuroradiology at the University of North Carolina. Divided into twelve chapters, the book begins with a chapter on new sequences for spinal MRI. Subsequent chapters cover imaging of craniospinal disorders, trauma to the spine and spinal cord, differentiation of benign versus malignant vertebral collapse, imaging of spinal tumours and vertebral augmentation procedures. The concluding chapters provide information on other non-vascular spinal interventions, and a concise review of post-operative imaging. Spinal Imaging: Critical Topics for Clinical Practice provides up to date guidance on MR neurographic techniques and image findings related to spinal tumours, and also details common and unusual MRI findings in patients with degenerative spine disease, and congenital spine conditions. Key Points Concise review of commonly used and new MRI sequences for spinal imaging Updates on MRI techniques and imaging findings for degenerative spine disease, congenital spine conditions, and spinal tumours Edited by Chief of the Division of Neuroradiology at the University of North Carolina
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