Mit den von anerkannten Sachkennern der Radiologie und der Frauenheilkunde erarbei- teten Beitragen fUr den Band XIII/2 des Handbuches der medizinischen Radiologie konnten erstmals in der Weltliteratur umfassende Zusammenstellungen des gesamten Wissensstof- fes auf dem Gebiet der gynakologischen Radiologie und der radiologisch-geburtshilflichen Diagnostik vorgelegt werden. Die Methodik und den Informationswert der Hysterosalpingographie hat FOCHEM abgehandeIt und gestiitzt auf die fundierten Ergebnisse eigener Arbeit, in klar gegliederten Kapiteln die morphologischen Rontgenbefunde des gesunden und kranken Uterus und der Tuben erlautert. Mit dem Beitrag tiber die gynakologische Rontgendiagnostik in der Padiatrie haben BENZ und WILLICH eine vollstandige Ubersicht der Ergebnisse ihres noch wenig bekannten Forschungsgebietes gegeben, das fUr viele Fachgebiete der Medizin groBe praktische Bedeutung erlangt hat. Die methodischen Grundlagen und den Informationswert der radiologischen Spezial- diagnostik in der Gynakologie haben GROTEMEYER und BREIT zusammengestellt. Einen grundlegenden Beitrag zur Anatomie und Topographie der Organe des weiblichen Bek- kens im Hinblick auf die Rontgen-Ganzkorper-Computer-Tomographie verdanken wir PLATZER, der das Fundament fUr die Bildanalyse dieser neuartigen diagnostischen Me- thode erarbeitet hat. Die spezielle Rontgendiagnostik der gynakologischen Tumoren mit Hilfe der Angio- graphie und Rontgen-Ganzkorper-Computer-Tomographie haben BREIT und ROHDE ab- gehandelt. In besonderen Kapiteln ist die oft vernachlassigte Rezidivdiagnostik bei Ge- schwiilsten von BREIT sowie LISSNER und SCHERER bearbeitet worden. Gestiitzt auf eigene Forschungs- und Entwicklungsarbeit geben die Autoren eine umfassende Ubersicht und berticksichtigen die wertvollen diagnostischen Informationen, die heute mit Hilfe der Rontgen-Ganzkorper-Computer-Tomographie fUr die klinische Arbeit zur VerfUgung stehen.

Advances in imaging are occurring at a brisk pace, and imaging techniques have great potential to act as pre-symptomatic predictors of disease as well as to chart the course of a disease. Neuroimaging has greatly advanced the understanding of brain function and its relationship to the anatomical substrate. This volume brings together internationally renowned imaging scientists, those studying the aging brain, industry experts, and clinicians to jointly examine the most current methods and their application to brain physiology, behavior, and age-related diseases.

These reports explore new technologies, data from recent neuroimaging initiatives, and translational research applications. Topics covered include (1) in vivo imaging of molecules, cells, and networks throughout the lifespan, (2) cutting edge imaging technologies and studies of the physiology of aging, (3) translational application of neuroimaging, and (4) emerging technologies in the private sector.

This volume is the proceedings of a meeting that celebrated the 25th anniversary of the American Federation for Aging Research and its longstanding history of philanthropy in the area of aging research.

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Creating New Medical Ontologies for Image Annotation focuses on the problem of the medical images automatic annotation process, which is solved in an original manner by the authors. All the steps of this process are described in detail with algorithms, experiments and results. The original algorithms proposed by authors are compared with other efficient similar algorithms. In addition, the authors treat the problem of creating ontologies in an automatic way, starting from Medical Subject Headings (MESH). They have presented some efficient and relevant annotation models and also the basics of the annotation model used by the proposed system: Cross Media Relevance Models. Based on a text query the system will retrieve the images that contain objects described by the keywords.

Colorectal Cancer Screening and Computerized Tomographic Colonography: A Comprehensive Overview is an authoritative volume on CT colonography. Structured in a manner that will allow the reader to understand the practical and larger public health issues surrounding both CT colonography and CRC screening in general, the text is designed to reach a broad audience of specialist clinicians and primary care physicians. The book provides an overview of the disease and risk factors of colorectal cancer, as well as the history and development of CTC as both a colorectal imaging and screening modality. The text also reviews the controversies, potential pitfalls, and exciting new directions and capabilities inherent in the practice of CTC. Filled with high quality images and authored by experts in the field, Colorectal Cancer Screening and Computerized Tomographic Colonography: A Comprehensive Overview is the definitive reference for clinicians interested in computerized tomographic colonography and CRC screening.

This book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbles. Examples in the book include multifunctional nanoparticles that are designed for multimodality imaging and simultaneous diagnostic and therapy (theranostic) applications.

Addressing the widespread need for a practical guide to imaging mass spectrometry (IMS), this book presents the protocols of IMS technology. As that technology expands, research groups around the world continue its development. Pharmaceutical companies are using IMS for drug analyses to study pharmacokinetics and medical properties of drugs. Drug research and disease-related biomarker screening are experiencing greater use of this technology, with a concurrent increase in the number of researchers in academia and industry interested in wider applications of IMS. Intended for beginners or those with limited experience with IMS technology, this book provides practical details and instructions needed for immediate know-how, including the preparation of animal tissue samples, the application of a matrix, instrumental operations, and data analysis, among others. By describing the foundations of IMS, this volume contributes to the ongoing development of the field and to progress in human health.

"Noninvasive Cerebrovascular Diagnosis" is the newest definitive text on the current techniques used in assessing vascular disorders. Readers will receive authoritative information and will be guided through the establishment and accreditation of a vascular laboratory and introduced to the physics of diagnostic testing. Chapters, written by selected experts, comprehensively explain the use of ultrasound in diagnosing cerebrovascular, renovascular, visceral ischemia and peripheral arterial disease as well as venous disorders and deep abdominal vascular conditions. Noninvasive Vascular Diagnosis contains over 300 illustrations, many of them in colour. Due to the special sections which give clinical correlations, this book will be invaluable to physicians who treat vascular disorders, surgeons, cardiologists, vascular radiologists and the vascular laboratory staff.

The first International Workshop on Machine Learning in Medical Imaging, MLMI 2010, was held at the China National Convention Center, Beijing, China on Sept- ber 20, 2010 in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) 2010. Machine learning plays an essential role in the medical imaging field, including image segmentation, image registration, computer-aided diagnosis, image fusion, ima- guided therapy, image annotation, and image database retrieval. With advances in me- cal imaging, new imaging modalities, and methodologies such as cone-beam/multi-slice CT, 3D Ultrasound, tomosynthesis, diffusion-weighted MRI, electrical impedance to- graphy, and diffuse optical tomography, new machine-learning algorithms/applications are demanded in the medical imaging field. Single-sample evidence provided by the patient's imaging data is often not sufficient to provide satisfactory performance; the- fore tasks in medical imaging require learning from examples to simulate a physician's prior knowledge of the data. The MLMI 2010 is the first workshop on this topic. The workshop focuses on major trends and challenges in this area, and works to identify new techniques and their use in medical imaging. Our goal is to help advance the scientific research within the broad field of medical imaging and machine learning. The range and level of submission for this year's meeting was of very high quality. Authors were asked to submit full-length papers for review. A total of 38 papers were submitted to the workshop in response to the call for papers.

The diagnostic investigation of menstrual dysfunction and sterility is a routine part of gynaecological practice. Hysteroscopy can expand the spectrum of diagnostic possibilities. The 2nd revised edition of this handbook aims to familiarise the gynaecologist with diagnostical hysteroscopy. About 100 colour plates facilitate the acquisition of this technique as well as the correct assessment of findings. The book is conceived for newcomers to hysteroscopy and should contribute to the further establishment of this method. 2nd revised edition 90case studiesof gynaecological practice

This book has been specifically designed to serve as a quick reference that will be of immediate help in decision making. The book is ordered alphabetically according to diagnoses. The intention is that the clinican consults the information on a suspected diagnosis, and then considers the surgical and radiological differential diagnoses that are listed. A total of 80 common diagnoses are covered. For each diagnosis, the left-hand page presents information relevant to the surgeon, while the right-hand page is designed for the radiologist. The information for the surgeon comprises clinical insights, including symptoms, warnings, controversies, important facts of which the surgeon should be aware, and the surgical differential diagnosis. The intention is to enable the surgeon to request the most suitable investigation using the appropriate terminology, ensuring that the correct test is done within the correct time frame. The radiologist is provided with lists of the primary and follow-on investigations, the imaging findings, and helpful tips, as well as the radiological differential diagnosis. Informative supporting images are included for each diagnosis. The authors are all experts in their fields, with extensive practical experience and in-depth knowledge of new imaging techniques. This book belongs in the pocket of every student, house officer, resident, medical officer, or generalist consultant who may be the first practitioner to see the patient.

The two-volume set LNCS 5761 and LNCS 5762 constitute the refereed proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2009, held in London, UK, in September 2009.

Based on rigorous peer reviews, the program committee carefully selected 259 revised papers from 804 submissions for presentation in two volumes. The first volume includes 125 papers divided in topical sections on cardiovascular image guided intervention and robotics; surgical navigation and tissue interaction; intra-operative imaging and endoscopic navigation; motion modeling and image formation; image registration; modeling and segmentation; image segmentation and classification; segmentation and atlas based techniques; neuroimage analysis; surgical navigation and robotics; image registration; and neuroimage analysis: structure and function.

The two-volume set LNCS 5761 and LNCS 5762 constitute the refereed proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2009, held in London, UK, in September 2009.

Based on rigorous peer reviews, the program committee carefully selected 259 revised papers from 804 submissions for presentation in two volumes. The first volume includes 125 papers divided in topical sections on cardiovascular image guided intervention and robotics; surgical navigation and tissue interaction; intra-operative imaging and endoscopic navigation; motion modeling and image formation; image registration; modeling and segmentation; image segmentation and classification; segmentation and atlas based techniques; neuroimage analysis; surgical navigation and robotics; image registration; and neuroimage analysis: structure and function.

Coronary artery disease is the most commonly encountered problem in adult cardiology in the world. Echocardiography is the most commonly used imaging modality encountered in cardiology practice in the world. Even though there are many Acute Coronary Syndrome (ACS) reference books and echocardiography reference books, there is no single practical book so far in the literature with focus on the combined topics. The authors believe that this will be the first book to provide information on how echocardiography can be used in, prevention, diagnosis and treatment of ACS.

Data mining can help pinpoint hidden information in medical data and accurately differentiate pathological from normal data. It can help to extract hidden features from patient groups and disease states and can aid in automated decision making. Data Mining in Biomedical Imaging, Signaling, and Systems provides an in-depth examination of the biomedical and clinical applications of data mining. It supplies examples of frequently encountered heterogeneous data modalities and details the applicability of data mining approaches used to address the computational challenges in analyzing complex data. The book details feature extraction techniques and covers several critical feature descriptors. As machine learning is employed in many diagnostic applications, it covers the fundamentals, evaluation measures, and challenges of supervised and unsupervised learning methods. Both feature extraction and supervised learning are discussed as they apply to seizure-related patterns in epilepsy patients. Other specific disorders are also examined with regard to the value of data mining for refining clinical diagnoses, including depression and recurring migraines. The diagnosis and grading of the world's fourth most serious health threat, depression, and analysis of acoustic properties that can distinguish depressed speech from normal are also described. Although a migraine is a complex neurological disorder, the text demonstrates how metabonomics can be effectively applied to clinical practice. The authors review alignment-based clustering approaches, techniques for automatic analysis of biofilm images, and applications of medical text mining, including text classification applied to medical reports. The identification and classification of two life-threatening heart abnormalities, arrhythmia and ischemia, are addressed, and a unique segmentation method for mining a 3-D imaging biomarker, exemplified by evaluation of osteoarthritis, is also present

To improve efficiency and reduce administrative costs, healthcare providers, insurance companies, and governments are increasingly using integrated electronic health record (EHR) and picture archiving and communication systems (PACS) to manage patients' medical information. Reflecting the latest applications of PACS technology, PACS and Digital Medicine: Essential Principles and Modern Practice discusses the essential principles of PACS, EHR, and related technological advancements as well as practical issues concerning the implementation, operation, and maintenance of PACS and EHR systems. The book focuses on various components of PACS that use state-of-the-art technologies. The authors first present topics to consider prior to implementation, including design principles for PACS components and theory. They also cover post-installation quality control; security and privacy policies; maintenance, including upgrade/integration with other information systems; and governing standards. Each chapter includes an introduction to basic concepts and principles relevant to the topics, before exploring challenges that PACS users may encounter in daily work. Discussions are supplemented with more than 130 illustrations, along with case studies of implementation in two organizations. A useful guide and broad overview of the field, this book presents key principles and practical steps for PACS and EHR implementations and maintenance. Although the technology and standards of healthcare IT will evolve over time, the theory and practical advice found in this text will remain pertinent in the future.

Presented in an interesting, historical and philosophical way, this book describes the current state of play in brain imaging, showing the differences among the different imaging modalities, and reviewing the knowledge about the chemical reactions in the brain, and their relationship to thinking, feeling and acting.

The book reviews all the results of PET and PET/CT imaging of the brain with all radiopharmaceuticals that bind to receptors in all recognized and classified mental diseases, as well as the studies on the localization of those sites that are activated by sensory or motor activity. The book illustrates the parts of the brain activated and deactivated during sensory perception, motion and other mental functions and explains how the process of neurotransmission takes place in chemical terms.

The book is a valuable reference resource for all those in nuclear medicine and radiology as well as the educated general public.

The acclaimed pocket atlas of the most common pathologic conditions seen on CT and MRI - more essential than ever, with new images and cases Designed for quick look-up at the point of care, this concise handbook provides technologists and students with CT and MRI findings of 200 pathologic conditions most often seen in day-to-day practice, along with pertinent clinical information. Each pathology listed has a single page of text accompanied by MRI and/or CT images, often providing multiple perspectives of the same pathology. The text includes a description of etiology, epidemiology, signs and symptoms, imaging characteristics, for CT and MRI, treatment, and prognosis statements. The book also includes a valuable opening section on the Principles of Imaging in Computed Tomography and Magnetic Resonance Imaging and an informative section on Contrast Media. Designed for portability and ease of use, this handbook enables technologists to quickly check pathologic imaging findings and essential clinical information without having to refer to large, heavy textbooks

The aim of this book is to present statistical problems and methods in a friendly way to radiologists, emphasizing statistical issues and methods most frequently used in radiological studies (e.g., nonparametric tests, analysis of intra- and interobserver reproducibility, comparison of sensitivity and specificity among different imaging modality, difference between clinical and screening application of diagnostic tests, ect.). The tests will be presented starting from a radiological "problem" and all examples of statistical methods applications will be "radiological."

This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this second volume includes computer assisted intervention and robotics, visualization and interaction, neuroscience image computing, computational anatomy, innovative clinical and biological applications, general biological imaging computing, computational physiology.

Intravoxel incoherent motion (IVIM) refers to translational movements which within a given voxel and during the measurement time present a distribution of speeds in orientation and/or amplitude. The concept was introduced in 1986 together with the foundation of diffusion MRI because it had been realized that flow of blood in capillaries (perfusion) would mimic a diffusion process and impact diffusion MRI measurements. IVIM-based perfusion MRI, which does not require injection of any tracer or contrast agent, has been first investigated in the brain, but is now experiencing a remarkable revival for applications throughout the body, especially for oncologic applications, from diagnosis to treatment monitoring. This book addresses a number of highly topical aspects of the field from leading authorities, introducing the concepts behind IVIM MRI, outlining related methodological issues, and summarizing its current usage and potential for clinical applications. It also presents future research directions, both in terms of methodological development and clinical application fields, extending to new, non-perfusion applications of IVIM MRI, such as virtual MR elastography.

The book introduces the fundamental aspects of digital imaging and covers four main themes: Ultrasound techniques and imaging applications, Magnetic resonance and MPJ in hospital, Digital imaging with X-rays, Emission tomography (PET and SPECT). Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advancements in the field. Some issues specific to the individual techniques are also treated, e.g. choice of radioisotopes or contrast agents, optimisation of data acquisition and storage, readout electronics, modelling and computer algorithms for imaging and measurement in ultrasounds and tomography applications.

This book constitutes the refereed proceedings of the 20th International Conference on Information Processing in Medical Imaging, IPMI 2007, held in Kerkrade, The Netherlands, in July 2007. It covers segmentation, cardiovascular imaging, detection and labeling, diffusion tensor imaging, registration, image reconstruction, functional brain imaging, as well as shape models and registration.

Since their discovery by Becquerel and RAntgen, ionising radiation and detectors for ionising radiation have played an ever more important role in medical diagnostics and therapy. The use of scintillating materials in the detection of ionising radiation for medical imaging is the main topic of this book intended for an audience of physicists and engineers. The book will be useful both to new researchers entering the field and to experts interested to learn about the latest developments.

It starts with an overview of the state of the art in using radiation detectors for medical imaging, followed by an in depth discussion of all aspects of the use of scintillating materials for this application. Possibilities to improve the performance of existing scintillating materials and completely new ideas on how to use scintillating materials are discussed in detail. The first 4 chapters contain a general overview of the applications of radiation detectors in medicine and present a closer look at the 3 most important subfields, X-ray imaging, gamma ray imaging and PET. One chapter is devoted to semiconductor detectors, a promising new area, and two chapters are devoted to recent technical advances in PET. The remaining 5 chapters deal with scintillating materials and their use in medical imaging.

Practical and clinically oriented, Specialty Imaging: Acute and Chronic Pain Intervention provides unique, authoritative guidance on the use of image-guided techniques for periprocedural analgesia and pain management procedures. Ideal for practicing and trainee interventional radiologists, pain physicians, and anesthesiologists, this one-stop resource is tailored to your decision support needs, with coverage of everything from neuroanatomy and specific pain conditions to interventional procedures for acute and chronic pain. Provides up-to-date content informed by best practices and the perspectives of both interventional radiology and anesthesiology Discusses key topics such as multimodal opioid sparing techniques as adjuncts and alternatives to the use of opioids for acute pain management, as well as shared decision making in interventional radiology pain management Demonstrates the new fascial pain blocks as well as sympathetic nerve blocks for periprocedural analgesia during interventional procedures Covers adult and pediatric acute and chronic pain conditions Integrates neuroanatomy and the "why" of clinical procedures for a better understanding of the pathways and various options for therapeutic intervention Presents information consistently, using a highly templated format with bulleted text for quick, easy reference Begins each section with a discussion of neuroanatomy, followed by succinct chapters that provide "how-to" information on a clinically useful, imaging-guided interventional procedure for treating a specific acute or chronic pain condition Features procedural videos and clear, high-quality drawings for visual reinforcement, e.g., sequential illustrations that show where nerves are located through successive peeling of anatomic layers Includes an Expert ConsultT eBook version that allows you to search all text, figures, and references on a variety of devices

The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This second volume collects 118 papers related to segmentation, validation and quantitative image analysis, brain image processing, and much more.