Data mining can help pinpoint hidden information in medical data and accurately differentiate pathological from normal data. It can help to extract hidden features from patient groups and disease states and can aid in automated decision making. Data Mining in Biomedical Imaging, Signaling, and Systems provides an in-depth examination of the biomedical and clinical applications of data mining. It supplies examples of frequently encountered heterogeneous data modalities and details the applicability of data mining approaches used to address the computational challenges in analyzing complex data. The book details feature extraction techniques and covers several critical feature descriptors. As machine learning is employed in many diagnostic applications, it covers the fundamentals, evaluation measures, and challenges of supervised and unsupervised learning methods. Both feature extraction and supervised learning are discussed as they apply to seizure-related patterns in epilepsy patients. Other specific disorders are also examined with regard to the value of data mining for refining clinical diagnoses, including depression and recurring migraines. The diagnosis and grading of the world's fourth most serious health threat, depression, and analysis of acoustic properties that can distinguish depressed speech from normal are also described. Although a migraine is a complex neurological disorder, the text demonstrates how metabonomics can be effectively applied to clinical practice. The authors review alignment-based clustering approaches, techniques for automatic analysis of biofilm images, and applications of medical text mining, including text classification applied to medical reports. The identification and classification of two life-threatening heart abnormalities, arrhythmia and ischemia, are addressed, and a unique segmentation method for mining a 3-D imaging biomarker, exemplified by evaluation of osteoarthritis, is also present

The book introduces the fundamental aspects of digital imaging and covers four main themes: Ultrasound techniques and imaging applications, Magnetic resonance and MPJ in hospital, Digital imaging with X-rays, Emission tomography (PET and SPECT). Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advancements in the field. Some issues specific to the individual techniques are also treated, e.g. choice of radioisotopes or contrast agents, optimisation of data acquisition and storage, readout electronics, modelling and computer algorithms for imaging and measurement in ultrasounds and tomography applications.

These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques. New in the Second Edition: Voltage-sensitive dyes imaging in awake behaving animals Imaging based on genetically encoded probes Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping Using pH-sensitive dyes for functional mapping Modulated imaging Calcium imaging of neuronal activity using 2-photon microscopy Fourier approach to optical imaging Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.

Ultrasound has replaced X-ray as the main imaging modality for the diagnosis of pelvic floor disorders in women. It now enables a cost-effective and non-invasive demonstration of bladder neck and pelvic organ mobility, vaginal, urethral and levator ani function and anatomy, and anorectal anatomy. Atlas of Pelvic Floor Ultrasound provides an introduction to pelvic floor imaging as well as a resource to be used during initial and more advanced practice. The integration of 4D View software and volume data for offline analysis on an accompanying DVD provides a simple and convenient means to train pattern recognition and quantitative analysis.

Since their discovery by Becquerel and RAntgen, ionising radiation and detectors for ionising radiation have played an ever more important role in medical diagnostics and therapy. The use of scintillating materials in the detection of ionising radiation for medical imaging is the main topic of this book intended for an audience of physicists and engineers. The book will be useful both to new researchers entering the field and to experts interested to learn about the latest developments.

It starts with an overview of the state of the art in using radiation detectors for medical imaging, followed by an in depth discussion of all aspects of the use of scintillating materials for this application. Possibilities to improve the performance of existing scintillating materials and completely new ideas on how to use scintillating materials are discussed in detail. The first 4 chapters contain a general overview of the applications of radiation detectors in medicine and present a closer look at the 3 most important subfields, X-ray imaging, gamma ray imaging and PET. One chapter is devoted to semiconductor detectors, a promising new area, and two chapters are devoted to recent technical advances in PET. The remaining 5 chapters deal with scintillating materials and their use in medical imaging.

The scanning tunneling microscope and the atomic force microscope, both capable of imaging and manipulating individual atoms, were crowned with the Nobel Prize in Physics in 1986, and are the cornerstones of nanotechnology today. The first edition of this book has nurtured numerous beginners and experts since 1993. The second edition is a thoroughly updated version of this 'bible' in the field. The second edition includes a number of new developments in the field. Non-contact atomic-force microscopy has demonstrated true atomic resolution. It enables direct observation and mapping of individual chemical bonds. A new chapter about the underlying physics, atomic forces, is added. The chapter on atomic force microscopy is substantially expanded. Spin-polarized STM has enabled the observation of local magnetic phenomena down to atomic scale. A pedagogical presentation of the basic concepts is included. Inelastic scanning tunneling microscopy has shown the capability of studying vibrational modes of individual molecules. The underlying theory and new instrumentation are added. For biological research, to increase the speed of scanning to observe life phenomena in real time is a key. Advanced in this direction is presented as well. The capability of STM to manipulate individual atoms is one of the cornerstones of nanotechnology. The theoretical basis and in particular the relation between tunneling and interaction energy are thoroughly presented, together with experimental facts.

This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this second volume includes computer assisted intervention and robotics, visualization and interaction, neuroscience image computing, computational anatomy, innovative clinical and biological applications, general biological imaging computing, computational physiology.

This book constitutes the refereed proceedings of the 20th International Conference on Information Processing in Medical Imaging, IPMI 2007, held in Kerkrade, The Netherlands, in July 2007. It covers segmentation, cardiovascular imaging, detection and labeling, diffusion tensor imaging, registration, image reconstruction, functional brain imaging, as well as shape models and registration.

This book addresses the question 'What is physics for?' Physics has provided many answers for mankind by extending his ability to see. Modern technology has enabled the power of physics to see into objects to be used in archaeology, medicine including therapy, geophysics, forensics and other spheres important to the good of society. The book looks at the fundamental physics of the various methods and how they are used by technology. These methods are magnetic resonance, ionising radiation and sound. By taking a broad view over the whole field it encourages comparisons, but also addresses questions of risk and benefit to society from a fundamental viewpoint. This textbook has developed from a course given to third year students at Oxford and is written so that it can be used coherently as a basis for shortened courses by omitting a number of chapters.

The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This second volume collects 118 papers related to segmentation, validation and quantitative image analysis, brain image processing, and much more.

The 7th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2004, was held in Saint-Malo, Brittany, France at the "Palais du Grand Large" conference center, September 26-29, 2004. The p- posaltohostMICCAI2004wasstronglyencouragedandsupportedbyIRISA, Rennes. IRISA is a publicly funded national research laboratory with a sta? of 370,including150full-timeresearchscientistsorteachingresearchscientistsand 115 postgraduate students. INRIA, the CNRS, and the University of Rennes 1 are all partners in this mixed research unit, and all three organizations were helpful in supporting MICCAI. MICCAI has become a premier international conference with in-depth - pers on the multidisciplinary ?elds of medical image computing, comput- assisted intervention and medical robotics. The conference brings together cl- icians, biological scientists, computer scientists, engineers, physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 516 full submissions (8 pages in length) and 101 short communications (2 pages) from 36 di?erent countries and 5 continents (see ?gures below). All submissions were reviewed by up to 4 external reviewers from the Scienti?c Review C- mittee and a primary reviewer from the Program Committee. All reviews were then considered by the MICCAI 2004 Program Committee, resulting in the acceptance of 235 full papers and 33 short communications.

Der praktische Leitfaden fur ein interdisziplinares

Management von Osophagus- und Magenkarzinomen Welche Rekonstruktionsverfahren gibt es nach Osophagusresektion?

- Wie kann man Magenfruhkarzinome lokal behandeln?

- Welche Moglichkeiten laparaskopischer Operationsverfahren gibt es?

- Wann ist eine intraoperative Strahlentherapie sinnvoll?

- Welche aktuellen Studien gibt es?

Internisten, Chirurgen und Radiologen

finden hier alle relevanten Fakten

zu den malignen Erkrankungen des oberen Gastrointestinaltrakts

- Anatomie, Atiologie und Epidemiologie

- Vorsorge und Fruherkennung

- Diagnostik, Pathologie und Stadieneinteilung

- Chirurgische Therapieverfahren

- Multimodale Therapiekonzepte

- Nachsorge und Palliativtherapie

- Prognosefaktoren

"

The acclaimed pocket atlas of the most common pathologic conditions seen on CT and MRI - more essential than ever, with new images and cases Designed for quick look-up at the point of care, this concise handbook provides technologists and students with CT and MRI findings of 200 pathologic conditions most often seen in day-to-day practice, along with pertinent clinical information. Each pathology listed has a single page of text accompanied by MRI and/or CT images, often providing multiple perspectives of the same pathology. The text includes a description of etiology, epidemiology, signs and symptoms, imaging characteristics, for CT and MRI, treatment, and prognosis statements. The book also includes a valuable opening section on the Principles of Imaging in Computed Tomography and Magnetic Resonance Imaging and an informative section on Contrast Media. Designed for portability and ease of use, this handbook enables technologists to quickly check pathologic imaging findings and essential clinical information without having to refer to large, heavy textbooks

The first in a three-volume set exploring Problems and Solutions in Medical Physics, this volume explores common questions and their solutions in Diagnostic Imaging. This invaluable study guide should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. It contains key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

Together with the companion volume LNCS 2489 this book constitutes the refereed proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2002, held in Tokyo, Japan, in September 2002.The 184 revised full papers presented were carefully reviewed and selected from 321 submissions. The two-volume proceedings offers main topical sections on medical robotics and endoscopic devices; validation; brain tumor, cortex, vascular, and imaging and analysis; segmentation; cardiac applications; computer-assisted diagnosis; tubular structures; interventions; simulation; modelling; statistical shape modelling; image registration; visualization; and novel imaging techniques.

The 6th International Conference on Medical Imaging and Computer-Assisted Intervention,MICCAI2003,washeldinMontr eal,Qu ebec,CanadaattheF- rmont Queen Elizabeth Hotel during November 15-18, 2003. This was the ?rst time the conference had been held in Canada. The proposal to host MICCAI 2003 originated from discussions within the Ontario Consortium for Ima- guided Therapy and Surgery, a multi-institutional research consortium that was supported by the Government of Ontario through the Ontario Ministry of E- erprise, Opportunity and Innovation. The objective of the conference was to o?er clinicians and scientists a - rum within which to exchange ideas in this exciting and rapidly growing ?eld. MICCAI 2003 encompassed the state of the art in computer-assisted interv- tions, medical robotics, and medical-image processing, attracting experts from numerous multidisciplinary professions that included clinicians and surgeons, computer scientists, medical physicists, and mechanical, electrical and biome- cal engineers. The quality and quantity of submitted papers were most impressive. For MICCAI 2003 we received a record 499 full submissions and 100 short c- munications. All full submissions, of 8 pages each, were reviewed by up to 5 reviewers, and the 2-page contributions were assessed by a small subcomm- tee of the Scienti?c Review Committee. All reviews were then considered by the MICCAI 2003 Program Committee, resulting in the acceptance of 206 full papers and 25 short communications. The normal mode of presentation at MICCAI 2003 was as a poster; in addition, 49 papers were chosen for oral presentation.

The 6th International Conference on Medical Imaging and Computer-Assisted Intervention,MICCAI2003,washeldinMontr eal,Qu ebec,CanadaattheF- rmont Queen Elizabeth Hotel during November 15-18, 2003. This was the ?rst time the conference had been held in Canada. The proposal to host MICCAI 2003 originated from discussions within the Ontario Consortium for Ima- guided Therapy and Surgery, a multi-institutional research consortium that was supported by the Government of Ontario through the Ontario Ministry of E- erprise, Opportunity and Innovation. The objective of the conference was to o?er clinicians and scientists a - rum within which to exchange ideas in this exciting and rapidly growing ?eld. MICCAI 2003 encompassed the state of the art in computer-assisted interv- tions, medical robotics, and medical-image processing, attracting experts from numerous multidisciplinary professions that included clinicians and surgeons, computer scientists, medical physicists, and mechanical, electrical and biome- cal engineers. The quality and quantity of submitted papers were most impressive. For MICCAI 2003 we received a record 499 full submissions and 100 short c- munications. All full submissions, of 8 pages each, were reviewed by up to 5 reviewers, and the 2-page contributions were assessed by a small subcomm- tee of the Scienti?c Review Committee. All reviews were then considered by the MICCAI 2003 Program Committee, resulting in the acceptance of 206 full papers and 25 short communications. The normal mode of presentation at MICCAI 2003 was as a poster; in addition, 49 papers were chosen for oral presentation.

Prepare for success on the thoracic imaging component of the radiology Core Exam! Thoracic Imaging: A Core Review, 2nd Edition, is an up-to-date, practical review tool written specifically for the Core Exam. This helpful resource contains 300 image-rich, multiple-choice questions with detailed explanations of right and wrong answers, fully revised content, and additional eBook questions to ensure you're ready for the Core Exam or recertification exam. Features questions in all exam areas, including imaging basics, normal anatomy, ICU radiographs, pulmonary pathology, pleural disease, vascular diseases relevant to thoracic imaging, and trauma. Questions accompanied with 1 or 2 high-quality radiographs, CT, MR, or ultrasound images. Provides concise answers with explanations of each choice followed by relevant, up-to-date references. Follows the structure and content of what you'll encounter on the test, conveniently organized by topic. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Exploration of Cortical Function summarizes recent research efforts aiming at the revelation of cortical population coding and signal processing strategies. Topics include optical detection techniques of population activity in the sub-millimeter range, advanced methods for the statistical analysis of these data, and biologically inspired neuronal modeling techniques for population activities in the frameworks of optimal coding, statistical learning theory, and mean-field recurrent networks.

Exploration of Cortical Function is unique in that it covers one complete branch of population-based brain research ranging from techniques for data acquisition over data analysis up to modeling techniques for the quantification of functional principles. The volume covers an area which is of great current interest to researchers working on cerebral cortex. The combination of models and image analysis techniques to examine the activity of large cohorts of neurons is especially intriguing and prone to considerable error and debate.

The intended readership is students and researchers from many disciplines, including neuroscience, biology, physics, and computer science, interested in how an interdisciplinary framework from biology advanced statistics and computational neuroscience can be used to gather a quantitative understanding of cortical function. Experimentalists may gain insight into statistical and neuronal modeling techniques, whereas theoreticians will find an introductory treatment of neuroanatomy, neurophysiology, and measurement techniques.

Together with the companion volume LNCS 2488 this book constitutes the refereed proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2002, held in Tokyo, Japan, in September 2002.The 184 revised full papers presented were carefully reviewed and selected from 321 submissions. The two-volume proceedings offers main topical sections on medical robotics and endoscopic devices; validation; brain tumor, cortex, vascular, and imaging and analysis; segmentation; cardiac applications; computer-assisted diagnosis; tubular structures; interventions; simulation; modelling; statistical shape modelling; image registration; visualization; and novel imaging techniques.

Clinical Imaging of the Small Intestine offers a complete review of small bowel radiology and its applications. With contributions from leading international authorities, the book provides the reader with the pertinent aspects of gastrointestinal radiology, specifically the problems of technique and interpretation that confront radiologists.The second edition was revised to include: - CT and MRI of the small bowel; - Sonography of the small bowel; - Assessing the activity of Crohn's disease with MRI; - Vascular disorders and small bowel obstructions; - Immune deficiency diseases; - Differential diagnosis based on both pathologic and radiologic findings; - New Figures and expanded index.The comprehensive scope of coverage makes this book a highly specialized but nonetheless state-of-the-art reference for those practitioners who have an interest in learning more about intestinal imaging, including radiologists, gastroenterologists and surgeons.

Dieses Buch dient der Standortbestimmung der verschiedenen Verfahren, die durch ausgewiesene Experten der verschiedenen Fachgebiete aktuell und in ubersichtlicher Form dargestellt werden. Dabei folgt einem Kapitel der interventionellen Kardiologie jeweils ein entsprechendes Kapitel der interventionellen Angiologie bzw. Radiologie, wodurch die enge Verwandtschaft, aber auch die Unterschiede leicht erkennbar werden.
Ziel der Herausgeber ist es, zum einen die interdisziplinare Diskussion anzuregen und zum anderen die Kenntnisse auerhalb des eigenen Bereiches bei gleicher Indikation zu vertiefen. Entsprechend wendet sich das Buch gleichermaen an die interventionell tatigen Kollegen der unterschiedlichen Fachrichtungen wie auch an den Allgemeinmediziner oder Internisten, der die Weichen fur eine erfolgreiche Weiterbehandlung seines Patienten stellen muss.

Advances in fluorescent proteins, live-cell imaging, and superresolution instrumentation have ushered in a new era of investigations in cell biology, medicine, and physiology. From the identification of the green fluorescent protein in the jellyfish Aequorea victoria to the engineering of novel fluorescent proteins, The Fluorescent Protein Revolution explores the history, properties, and applications of these important probes. The book first traces the history of fluorescent proteins and the revolution they enabled in cellular imaging. It then discusses fluorescent proteins with novel photophysical properties. The book also covers several cutting-edge imaging applications. These include superresolution microscopy of cellular fine structures, FRET microscopy to visualize protein interactions and cell-signaling activities inside living cells, photobleaching and photoactivation techniques to visualize protein behaviors, techniques that exploit plant and algal photoreceptors to enable light-regulated control of enzymatic activities, and the noninvasive imaging of tumor-host interactions in living animals. In color throughout, this book presents the fundamental principles and latest advances in the field, including the associated development of imaging techniques that exploit fluorescent proteins. It is accessible to a broad audience, from optical imaging experts to novices needing an introduction to the field.

In this small volume experts provide succinct answers to freuqently asked questions about the properties and handling of X-ray contrast media. It is an excellent reference source for all using these agents. Basic information is given on the development, toxicology, pharmacology, pharmacokinetics and clinical testing of contrast agents and in question and answer form on the problems and adverse events which may be associated with them. Most of the book is concerned with the most frequently used iodinated X-ray agents but there are useful sections on the magnetic resonance and ultrasound echo enhancing agents which are assuming greater and increasing importance. This book will be of interest to both radiologists and clinicians.

The 1999 international conference on Information Processing in Medical Imaging (IPMI '99) was the sixteenth in the series of biennial meetings and followed the successful meeting in Poultney, Vermont, in 1997. This year, for the rst time, the conference was held in central Europe, in the historical Hungarian town of Visegr ad, one of the most beautiful spots not only on the Danube Bend but in all Hungary. The place has many historical connections, both national and international. The castle was once a royal palace of King Matthias. In the middle ages, the Hungarian, Czech, and Polish kings met here. Recently, after the summit meeting of reestablished democracies in the area, it became a symbol for the cooperation between central European countries as they approached the European Union. It was thus also symbolic to bring IPMI, in the year of the 30th anniversary of its foundation, to this place, and organize the meeting with the close cooperation of local and traditional western organizers. It also provided a good opportunity to summarize brie?y a history of IPMI for those who were new to the IPMI conference. This year we received 82 full paper submissions from all over the world. Of these, 24 were accepted as oral presentations. These were divided into 6 sessions. In spite of our e orts, it was found to be impossible to make these sessions fully balanced and homogeneous.