The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these imaging particles can be designed to fulfill specific requirements for applications across different imaging modalities. It presents, for the first time, a comprehensive interdisciplinary overview of the impact nanoparticles have on biomedical imaging and is a common central resource for researchers and teachers.

The book introduces the fundamental aspects of digital imaging and covers four main themes: Ultrasound techniques and imaging applications, Magnetic resonance and MPJ in hospital, Digital imaging with X-rays, Emission tomography (PET and SPECT). Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advancements in the field. Some issues specific to the individual techniques are also treated, e.g. choice of radioisotopes or contrast agents, optimisation of data acquisition and storage, readout electronics, modelling and computer algorithms for imaging and measurement in ultrasounds and tomography applications.

Imaging in Oncology will serve as an up-to-date, attractive book of oncologic imaging for radiologists, oncologists, radiation therapists and others involved in oncologic care. This volume provides pertinent clinical and research information that underpins accurate interpretation and sensible use of cancer imaging. It reviews the role of established and upcoming techniques in plain radiography, ultrasound, CT, MR nuclear medicine, PET and PET/CT for oncologic imaging as well as image-guided intervention. The book also highlights new developments and advances in oncologic imaging. Imaging in Oncology will appeal to physicians in practice and in training and to all interested in oncologic imaging.

This title is part of a two-volume set that constitute the refereed proceedings of the 10th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2007. Coverage in this second volume includes computer assisted intervention and robotics, visualization and interaction, neuroscience image computing, computational anatomy, innovative clinical and biological applications, general biological imaging computing, computational physiology.

NEW FRONTIERS IN BIOMAGNETISM contains selected papers based on presentations at the 15th International Conference on Biomagnetism (Biomag 2006), held in Vancouver between the 20th and 26th of August, 2006. The conference brought together over 500 scientists and specialists from around the world to present the latest scientific and technological developments in the field of Biomagnetism - the measurement of magnetic signals produced by electric currents in the human body. The study of the minute magnetic fields resulting from heart and muscle contraction, signal conduction in the nervous system, or by the magnetization of biological tissue has grown steadily since the 5th World Conference on Biomagnetism that was held in Vancouver in August of 1984.Although the conference covered many facets of biomagnetism research, the focus for this year's conference was on new frontiers in biomagnetism - the development of new applications and areas of research. One emphasis was on the application of Magnetoencephalography (MEG) to the study of human development and its potential to help understand the physiological underpinnings of language and cognitive development in children, including neurodevelopmental disorders, such as Down Syndrome, autism and language impairment. There were also many exciting contributions on the latest techniques for the precise localization of brain activity using MEG, and related methods for the study of brain dynamics and distributed networks of neural activity. These novel approaches to the study of human brain function promise to provide new insights into the organization of neural systems underlying motor planning, perception, memory and cognition. Other areas of rapid development discussed in New Frontiers in Biomagnetism include the application of biomagnetic measures in the diagnosis and treatment of epilepsy, psychiatric disorders such as schizophrenia, and the use of MEG for presurgical functional mapping. Special sessions were also dedicated to the latest developments in Magnetocardiography (MCG) for the assessment of cardiovascular disease and associated disorders of the electrical activity of the heart. This year's conference also held a special symposium in honour of the late Sam Williamson, with presentations from his former colleagues and students that reviewed his life's work and contributions to the field of neuromagnetism. NEW FRONTIERS IN BIOMAGNETISM aims to provide a comprehensive overview of the latest developments in the field of Biomagnetism and its application to the study of human biological systems. The many new developments and breakthroughs presented at Biomag 2006 made a significant contribution to the advancement of the understanding of brain and cardiac function and provided new tools for clinical applications of this new knowledge.

Ultrasound has replaced X-ray as the main imaging modality for the diagnosis of pelvic floor disorders in women. It now enables a cost-effective and non-invasive demonstration of bladder neck and pelvic organ mobility, vaginal, urethral and levator ani function and anatomy, and anorectal anatomy. Atlas of Pelvic Floor Ultrasound provides an introduction to pelvic floor imaging as well as a resource to be used during initial and more advanced practice. The integration of 4D View software and volume data for offline analysis on an accompanying DVD provides a simple and convenient means to train pattern recognition and quantitative analysis.

The book introduces the fundamental aspects of digital imaging and covers four main themes: Ultrasound techniques and imaging applications, Magnetic resonance and MPJ in hospital, Digital imaging with X-rays, Emission tomography (PET and SPECT). Each of these topics is developed by analysing the underlying physics principles and their implementation, quality and safety aspects, clinical performance and recent advancements in the field. Some issues specific to the individual techniques are also treated, e.g. choice of radioisotopes or contrast agents, optimisation of data acquisition and storage, readout electronics, modelling and computer algorithms for imaging and measurement in ultrasounds and tomography applications.

Since their discovery by Becquerel and RAntgen, ionising radiation and detectors for ionising radiation have played an ever more important role in medical diagnostics and therapy. The use of scintillating materials in the detection of ionising radiation for medical imaging is the main topic of this book intended for an audience of physicists and engineers. The book will be useful both to new researchers entering the field and to experts interested to learn about the latest developments.

It starts with an overview of the state of the art in using radiation detectors for medical imaging, followed by an in depth discussion of all aspects of the use of scintillating materials for this application. Possibilities to improve the performance of existing scintillating materials and completely new ideas on how to use scintillating materials are discussed in detail. The first 4 chapters contain a general overview of the applications of radiation detectors in medicine and present a closer look at the 3 most important subfields, X-ray imaging, gamma ray imaging and PET. One chapter is devoted to semiconductor detectors, a promising new area, and two chapters are devoted to recent technical advances in PET. The remaining 5 chapters deal with scintillating materials and their use in medical imaging.

This book constitutes the refereed proceedings of the 20th International Conference on Information Processing in Medical Imaging, IPMI 2007, held in Kerkrade, The Netherlands, in July 2007. It covers segmentation, cardiovascular imaging, detection and labeling, diffusion tensor imaging, registration, image reconstruction, functional brain imaging, as well as shape models and registration.

This atlas comprises a complete and extensive exposure of the spatial and temporal aspects of human cardiac development as seen with scanning electron microscopy. Apart from serving as a unique overview on cardiac development in the human embryo, this atlas gives an updated morphological reference of cardiac embryology for topographic correlation and enables the projection of experimental results in animals to the human situation.

The use of scintillating materials in the detection of ionising radiation for medical imaging is the main topic of this book. It starts with an overview of the state of the art in using radiation detectors for medical imaging, followed by an in depth discussion of all aspects of the use of scintillating materials for this application. Possibilities to improve the performance of existing scintillating materials and completely new ideas on how to use scintillating materials are discussed in detail. The first 4 chapters contain a general overview of the applications of radiation detectors in medicine and present a closer look at the 3 most important subfields, X-ray imaging, gamma ray imaging and PET. One chapter is devoted to semiconductor detectors, a promising new area, and two chapters are devoted to recent technical advances in PET. The remaining 5 chapters deal with scintillating materials and their use in medical imaging.

The two-volume set LNCS 4190 and LNCS 4191 constitute the refereed proceedings of the 9th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2006. The program committee carefully selected 39 revised full papers and 193 revised poster papers for presentation in two volumes. This second volume collects 118 papers related to segmentation, validation and quantitative image analysis, brain image processing, and much more.

Nuclear medicine is a specialized medical field based on the application of radiopharmaceuticals, i.e. drugs associated to radioactivity, for diagnosis or therapeutic purposes. In the past fifty years, nuclear medicine has progressed in such a way that it is now a major tool in hospitals. Nowadays, this technology enables to better detect, observe and describe diseases, and also to improve treatments. Cancer therapy is the main application of this speciality. Once injected to the patient, the radiopharmaceutical drug aims selectively at the tumoral cells, including the metastases, settles there and emits radiation. Depending on the type of radiation, the drug will either help to identify the cells or to destroy them. Recent breakthroughs in this technology bring new perspectives to oncology, haematology and neurology. At the same time, since the beginning of the 21st century nuclear medicine has also benefited from a double revolution in terms of imaging technology. On the one hand, the Positron Emission Tomography (PET) made a real impact with a polyvalent imaging drug called FDG. On the other hand, a new tool combining functional and morphological imaging (PET-CT) was very recently made available to the medical community. This scientific book aims to introduce nuclear medicine to a larger audience, pointing out, among other things, the difficulties both physicians and patients meet when trying to access new technologies. There are still some issues to overcome, but recent scientific breakthroughs bring great hopes for patients in the near future.

This volume gives a survey on mathematical and computational methods in image registration. During the last year sophisticated numerical models for registration and efficient numerical methods have been proposed. Many of them are contained in this volume. The book also summarizes the state-of-the-art in mathematical and computational methods in image registration. In addition, it covers some practical applications and new directions with industrial relevance in data processing.

Positron emission tomography (PET) has been at the forefront of fu- tional and molecular imaging for a number of years. The future of di- nostic imaging depends upon the ability to change from imaging anatomy to examining the processes at work in the body. The fact that there are now monographs examining particular aspects of PET, such as this book on the examination of children, speaks to the newly won maturity of PET. The authors are to be congratulated for the timely appearance of this volume. In recent years, PET has transformed the contributions of nuclear medicine to the diagnosis, staging, and follow-up of patients with cancer. Children with cancer deserve the very best and most comp- sionate care that society can provide. Ultimately the greatest comp- sion we can offer as physicians is to provide the best possible care. Those charged with creating public policy in the context of diagnostic medicine must make common cause with physicians and other sci- tists to ensure that that best possible care is realized at the bedside. All of the evidence suggests that PET is central to such optimal cancer care. In addition to the distinguished cast of physicians and researchers who contributed to this book, I welcome the contributions from te- nologists who are a key part of the interaction between the diagnostic process and the sick or potentially sick child. Good care is contingent upon putting parents and child at ease, and the technologist has a lead role in this.

Ischemic heart disease (IHD) is the main cause of morbidity and mortality in the developed world. Despite advances and new developments in primary and secondary prevention, the prevalence of the disease and its complications remain high. Early detection has been shown to reduce significantly the risk of cardiac events such as myocardial infarction and death, while modern cardiology now provides specialists and general physicians with a variety of procedures for the assessment of IHD using noninvasive methods. This book reviews the currently available imaging techniques for the diagnosis and management of IHD. In addition, the role of cardiac imaging for the detection of viability and hibernation is discussed in detail. A series of highly illustrated cases is included on the CD-ROM to illustrate the applications and rationale behind the use of cardiac imaging for the evaluation of patients with IHD in different clinical scenarios.

Would you stick your head in a microwave oven? Well would you? Of course not. Technology has transformed this planet into an open microwave system with its satellite transmissions. This book examines what the health consequences are. This book simply points out that the gradual rise in illness across broad geographic areas are an early indicator of microwave illness, independently of what the experts lead you to believe. The handwriting is already on the wall and most of know that something is wrong. This book discusses in simple terms the effects of microwave radiation on the human body. I utilize dosimetry studies done by the US Air Force, which outline in clear terms what organs of the body are most vulnerable to cumulative microwave exposure. I outline the mechanisms by which slow exposure is masquerading as various illnesses across this country. We are on the verge of a health care crisis which threatens to bankrupt our society and health care system. Whether we like to consider it or not the planet that we are living on has been transformed into an open microwave system. In this book I examine the common link between microwave radiation and seemingly unrelated illnesses. The book demonstrates that the rising incidence of certain illnesses and cancers across broad geographic regions parallels the increasing rise in exposure and use of microwave radiation. This book is a common sense approach to the subject which is presented in a clear language that the laymen can understand. Also it is liberally referenced from the scientific literature. The book is designed to be generally informative as well as a reference source for the average reader. Additionally I have provided a wealth ofresources that have been shown to be beneficial to offset the consequences of excess microwave exposure.

Pixel detectors are a particularly important class of particle and radiation detection devices. They have an extremely broad spectrum of applications, ranging from high-energy physics to the photo cameras of everyday life. This book is a general purpose introduction into the fundamental principles of pixel detector technology and semiconductor-based hybrid pixel devices. Although these devices were developed for high-energy ionizing particles and radiation beyond visible light, they are finding new applications in many other areas. This book will therefore benefit all scientists and engineers working in any laboratory involved in developing or using particle detection.

Evidence-Based Imaging presents the radiologist with a user-friendly guide to the evidence-based science and the merit behind the diagnostic imaging studies performed in medicine. This book gives the reader a clinically relevant overview of epidemiology, selection of subjects for imaging, selection of imaging strategies, imaging test performance and cost, cost-effectiveness analysis, and applicability to children. Nine major areas of medical imaging are covered, with an emphasis on common diseases. These include Oncology, Neuroimaging, Gastroenterology, Pediatrics, Respiratory System, Musculoskeletal, Cardiovascular, Trauma, and Urologic.

Radiologists, clinicians, residents, and others with an interest in medical imaging and a desire to keep current with the vast amount of evidence-based literature will find this text extremely useful.

The spectrum of occupational and environmental diseases has changed markedly in recent years. New industrial processes have led to the production and use of a wide range of chemicals, metals, and alloys, an increasing number of which have been reported to cause interstitial lung disease in exposed workers. Thus, while the workforce in coal mining and asbestos handling has decreased, new groups of workers are at risk of exposure to agents potentially responsible for pneumoconiosis. This well-illustrated book, written by internationally acclaimed experts, provides a comprehensive approach to modern imaging of environmental and occupational diseases of the chest. The first part of the book addresses the basic knowledge required to understand imaging in this context, while the second focuses on the imaging results achieved in a variety of specific disorders. There is particular emphasis on thin-section computed tomography since this technique facilitates the detection of early subclinical abnormalities.

The 8th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2005, was held in Palm Springs, California, USA, at the Riviera Resort, October 26-29, 2005. MICCAIhasbecomeapremierinternationalconferencewithin-depthpapers on the multidisciplinary ?elds of medical image computing, computer-assisted interventionandmedicalrobotics. Theconferencebringstogetherclinicians,b- logicalscientists, computer scientists, engineers,physicists and other researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The impact of MICCAI increases each year and the quality and quantity of submitted papers this year was very impressive. We received a record 632 full submissions (8 pages in length), an increase of 22% from 2004, from 36 di?erent countries and 5 continents (see ?g. 2). Based on a decision of the MICCAI board, this year's conference employed a double-blind review procedure on a trial basis. Our Program Committee was made up of 11 area chairs, each of whom supervised the review of almost 60 papers. Four reviews were generated for each paper from 262 reviewers and the area chairs. A ?nal paper selection meeting took place during two days in early June 2005 in Chapel Hill, North Carolina. We are especially grateful to Elizabeth Bullitt, Polina Golland, David Haynor, Rasmus Larsen, Greg Hager and Daniel Ruc .. kert, who attended this meetingandhelpedusmakethe?nalselections. MartinStynerprovidedvaluable help with information management and the Web-site, and James Stewart is acknowledgedforreliableandtimelysupportoftheWeb-basedreviewingsystem. Wearegratefultoeveryonewhoparticipatedinthe reviewprocess;theydonated a large amount of time and e?ort to make these volumes possible and insure a highlevelofquality.

A practical guide for radiologists on providing high yield disease-specific reports Multiple studies show that referring physicians have a clear preference for structured radiology reports due to clarity and ease of interpretation, yet a one-size-fits all approach does not address disease complexities. Concurrently, the use of structured radiology templates has increased, driven in part by the need to comply with big data and artificial intelligence as well as reimbursement. Standardization of reporting is one of the first essential steps in the transformation of radiology from "the art of imaging" to a robust data science. Radiology Structured Reporting Handbook: Disease-Specific Templates and Interpretation Pearls by Professors Olga R. Brook, Wieland H. Sommer, and esteemed colleagues is a highly practical guide on structured reporting for every major area of radiology. Featuring disease-specific templates, the book is organized in six sections and 53 chapters. Section one covers core foundation topics, from different definitions of structured reporting and pros and cons to change management and how to build templates. Five disease-specific sections encompass specific cancers and a variety of abdominal, thoracic, neurological, and cardiovascular diseases and conditions. Key Highlights Downloadable disease-specific templates for a variety of clinical entities including cardiovascular, thoracic, abdominal, oncological, and neuroradiology Essential interpretation pearls for specific diseases from top experts in a bullet format, accompanied by relevant figures and tables Together, the templates and pearls provide an essential and unique practice resource for optimal and clinically relevant reporting. The book also serves as a succinct educational tool for radiology trainees and practicing radiologists who may not interpret specific highly specialized types of studies on a daily basis. This book includes complimentary access to a digital copy on https://medone.thieme.com.

This scholarly set of well-harmonized volumes provides indispensable and complete coverage of the exciting and evolving subject of medical imaging systems. Leading experts on the international scene tackle the latest cutting-edge techniques and technologies in an in-depth but eminently clear and readable approach. Complementing and intersecting one another, each volume offers a comprehensive treatment of substantive importance to the subject areas. The chapters, in turn, address topics in a self-contained manner with authoritative introductions, useful summaries, and detailed reference lists. Extensively well-illustrated with figures throughout, the five volumes as a whole achieve a unique depth and breath of coverage. As a cohesive whole or independent of one another, the volumes may be acquired as a set or individually.