This book constitutes the refereed proceedings of the First International Workshop on Perinatal, Preterm and Paediatric Image Analysis, PIPPI 2022, held in conjunction with the 25th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2022, in Singapore, Singapore, in September 2021. The 10 full papers and 1 short papers presented at PIPPI 2022 were carefully reviewed and selected from 12 submissions. PIPPI 2022 workshop complements the main MICCAI conference by providing a focused discussion of perinatal and paediatric image analysis, including the application of sophisticated analysis tools to fetal, neonatal and paediatric imaging data.

This book constitutes the refereed proceedings of the first International Workshop on Cancer Prevention through Early Detection, CaPTion, held in conjunction with the 25th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2022, in Singapore, Singapore, in September 2022. The 16 papers presented at CaPTion 2022 were carefully reviewed and selected from 21 submissions. The workshop invites researchers to submit their work in the field of medical imaging around the central theme of early cancer detection, and it strives to address the challenges that are required to be overcomed to translate computational methods to clinical practice through well designed, generalizable (robust), interpretable and clinically transferable methods.

Over recent years the MRCS viva examination has increasingly made use of radiological imaging to facilitate the discussion of anatomy relevant to surgical practice. It is rare for junior doctors to receive adequate exposure to radiology in their day-to-day surgical practice, which makes preparation for this part of the examination difficult. For many, examinations are stressful. The last thing a candidate needs is to be faced with unfamiliar radiological images. This review of surgically relevant radiological imaging aims to prevent initial uncertainties and will allow candidates to discuss relevant anatomy and score valuable points. An invaluable addition to any revision plan, this title also: * highlights typical anatomy viva questions * familiarizes candidates with a range of images of differing modalities (plain film, fluoroscopy, computed tomography and magnetic resonance imaging) * introduces different planes of imaging, enabling candidates to deal with unusual coronal or sagittal views with confidence * gives concise but detailed notes for quick consultation

This atlas provides a practically applicable didatic case-based guide to the use of cardiac imaging in patient care during and after cancer therapy. It features detailed information on a variety of imaging modalities, including transesophageal echocardiography, magnetic resonance angiography and positron emission tomography. A range of actual patient presentations are included covering both diagnosis and management during curative and palliative surgery, as well as cancer pharmacotherapy with the use of drugs including Trastuzumab, Anthracycline, Cisplatin and Carboplatin. Topics relevant to survivorship are also described. Atlas of Imaging in Cardio-Oncology enables the reader to develop a deep understanding of how to utilise a variety of imaging modalities used in cardio-oncology in a range of scenarios. It provides a critical and timely resource for the trainee and experienced cardiologist, oncologist and radiologist.

Mit neu entwickelten diagnostischen Moeglichkeiten und verbesserten Therapieverfahren ist eine zunehmend differenzierte Behandlung von Lungenmetastasen boesartiger Tumoren moeglich geworden. Je nach Ursprungstumor und klinischer Situation wird ein unterschiedliches Vorgehen empfohlen. Neben onkologischen Gesichtspunkten ruckt auch die verbleibende Lungenfunktion in den Mittelpunkt des Interesses. Die moderne Bildgebung, offene und minimal invasive Operationsverfahren und interdisziplinare Therapiekonzepte zu den einzelnen Tumorentitaten sind detailliert und praxisorientiert beschrieben.

Interventional radiological techniques are becoming increasingly important in the treatment of both primary and secondary malignant liver tumours. Surgery for liver tumours can be effective but carries considerable risks and new techniques have recently been developed. This volume provides an account of interventional radiological methods by some of the greatest experts in the field. It includes chapters on cryotherapy, chemoembolization and radiofrequency ablation and an extensive chapter on imaging techniques. The scientific background of these techniques, the pathology of the diseases involved and an analysis of more traditional surgical methods are also described. This text brings together the latest advances in this fast-developing field.

This book explains the principles of biosignal processing and its practical applications using MATLAB. Topics include the emergence of biosignals, electrophysiology, analog and digital biosignal processing, signal discretization, electrodes, time and frequency analysis, analog and digital filters, Fourier-transformation, z-transformation, pattern recognition, statistical data analysis, physiological modelling and applications of EEG, ECG, EMG, PCG and PPG signals. Additional scientifi c contributions on motion analysis by guest authors Prof. Dr. J. Subke and B. Schneider as well as classification of PPG signals by Dr. U. Hackstein.

Modern applications of nuclear chemistry concern various scientific disciplines. This new edition of Volume 2 Nuclear- and Radiochemistry: Modern Applications summarizes recent knowledge on radiation measurement and dosimetry, highsensitive, high-selective, and non-destructive analytical technologies, environmental aspects and nuclear dating, state-of-the-art research on actinides and radioelements, nuclear energy, and molecular diagnosis and patient treatment for nuclear medicine. Individual topics are presented by leading experts. This 2nd edition has updated literature references and includes new material throughout. The reader is also referred to the new edition of Volume 1 Nuclear- and Radiochemistry: Introduction.

Nuclear chemistry represents a vital fi eld of basic and applied research. This Volume 1 Nuclear- and Radiochemistry: Introduction describes the relevant parameters of stable and unstable atomic nuclei, the various modes of radioactive transformations, the corresponding types of radiation, and fi nally the mechanisms of nuclear reactions. The 2nd edition has updated the chapters throughout with additional material. The reader is also referred to the new edition of Volume 2 Nuclear- and Radiochemistry: Modern Applications.

Radiologic investigations can be confusing to clinicians and radiologists alike. Questions invariably arise as to which type of imaging study best answers the clinical question posed. Once a modality is determined, decisions must be made regarding the technical manner in which the study is performed and if intravenous contrast is required. Patient factors, risks, benefits, and other variables must also be considered. This pocket guide is written for anyone who needs to understand enough about radiology to know which study to order in a patient workup. The book addresses imaging studies by modality, body region, and type of study in bulleted outline format for easy reference. General considerations for each modality including advantages and disadvantages are presented, followed by patient preparation and requirements for each type of examination. Dr. Catanzano explains how specific studies are performed and what information can be obtained, study indications, contraindications, and limitations. The book also includes an appendix of tables.

Imaging studies provide crucial information on disease extent in head and neck malignancies. A thorough knowledge of the loco-regional anatomy of this complex area and a proper understanding of the natural disease spread pattern are prerequisites in the interpretation of these imaging studies. Tumor extent influences tumor staging, predicts outcome and influences treatment choices. Knowledge of the different treatment options and expected post-therapeutic tissue changes are also critical in order to use imaging adequately in the surveillance of these patients. After an introductory chapter on epidemiology and clinical signs, this book reviews the pertinent imaging findings for each of the major anatomical subsites. Emphasis is on CT and MRI, but PET and ultrasound are also discussed where appropriate. Reviews on modern surgical and radiotherapeutic techniques are included, helping the reader to understand post-treatment tissue changes and how to differentiate these from tumor recurrence or treatment complications.

This book is an ideal introduction to the specialty of post mortem computed tomography (PMCT). It will serve as a comprehensive yet accessible guide to the understanding and interpretation of whole-body studies for both hospital and community settings. Both normal post mortem appearances and findings associated with a wide range of diagnoses encountered in real cases from the coronial service are presented with the aid of numerous images. The coverage encompasses not only findings in all anatomic regions but also the imaging appearances in cases following targeted coronary angiography, attempted cardiopulmonary resuscitation and various special circumstances such as suicide. The inclusion of many practical tips and possible pitfalls will support the radiologist to become more confident when reporting PMCT, while for the more experienced practitioner the wealth of examples will serve as a useful resource. In addition to radiologists, the book will be of value for pathologists at all levels of experience and anyone needing to understand the role and limitations of PMCT.

This book focuses on congenital heart disease (CHD) and emerging imaging technologies. It covers all clinically relevant aspects of the fascinating new cardiac imaging technologies, including a comprehensive explanation of their basic principles, practical aspects of novel clinical applications, and detailed descriptions of specific uses in the broad spectrum of clinically important adult CHD. Innovations and emerging technologies for diagnosis and therapeutics, evaluation and treatment are continually evolving, and due to these advances in non-invasive diagnosis, there has been a significant improvement in the survival rates for CHD patient. Novel approaches to trans-catheter interventions and advances in echocardiography, MRI and CT imaging are being developed and incorporated into routine clinical practice, while emerging three-dimensional printing technologies are fundamentally affecting patient care, research, trainee education, and interactions between multidisciplinary teams, patients, and caregivers. In addition, translational technologies on the horizon promise to take this nascent field even further. Exploring the applicability of these emerging technologies in improving our understanding of complex congenital cardiac defect anatomy and physiology will provide new treatment options for this unique population. Written by experts in the field who are also involved in patient care, this book discusses the practical application of innovations in advanced multimodality imaging in the daily clinical routine and offers tips and tricks for beginners.

Over the last decade, some of the greatest achievements in the field of neuroimaging have been related to remarkable advances in magnetic resonance techniques, including diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. Such techniques have provided valuable insights into tissue microstructure, microvasculature, metabolism and brain connectivity. Previously available mostly in research environments, these techniques are now becoming part of everyday clinical practice in a plethora of clinical MR systems. Nevertheless, despite growing interest and wider acceptance, there remains a lack of a comprehensive body of knowledge on the subject, exploring the intrinsic complexity and physical difficulty of the techniques. This book focuses on the basic principles and theories of diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. It also explores their clinical applications and places emphasis on the associated artifacts and pitfalls with a comprehensive and didactic approach. This book aims to bridge the gap between research applications and clinical practice. It will serve as an educational manual for neuroimaging researchers and radiologists, neurologists, neurosurgeons, and physicists with an interest in advanced MR techniques. It will also be a useful reference text for experienced clinical scientists who wish to optimize their multi-parametric imaging approach.

This book constitutes the Second International Challenge on Kidney and Kidney Tumor Segmentation, KiTS 2021, which was held in conjunction with the 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021. The challenge took place virtually on September 27, 2021, due to the COVID-19 pandemic. The 21 contributions presented were carefully reviewed and selected from 29 submissions. This challenge aims to develop the best system for automatic semantic segmentation of renal tumors and surrounding anatomy.

This volume provides a thought-provoking perspective on the empirical and analytic study of body form and composition. The techniques used for measuring body components such as fat, water, lean tissue, bone mass and bone density are evaluated against potential 'gold standards'. The nature of regional differences, developmental changes, pathological abnormalities, and the impact of heredity and environment in shaping body composition are discussed in the context of human evolution. All those concerned with biological anthropology, both clinicians and researchers, will find this book of great interest.

This book constitutes the proceedings of the 12th International Workshop on Statistical Atlases and Computational Models of the Heart, STACOM 2021, as well as the M&Ms-2 Challenge: Multi-Disease, Multi-View and Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge.The 25 regular workshop papers included in this volume were carefully reviewed and selected after being revised. They deal with cardiac imaging and image processing, machine learning applied to cardiac imaging and image analysis, atlas construction, artificial intelligence, statistical modelling of cardiac function across different patient populations, cardiac computational physiology, model customization, atlas based functional analysis, ontological schemata for data and results, integrated functional and structural analyses, as well as the pre-clinical and clinical applicability of these methods. In addition, 15 papers from the M&MS-2 challenge are included in this volume. The Multi-Disease, Multi-View & Multi-Center Right Ventricular Segmentation in Cardiac MRI Challenge (M&Ms-2) is focusing on the development of generalizable deep learning models for the Right Ventricle that can maintain good segmentation accuracy on different centers, pathologies and cardiac MRI views. There was a total of 48 submissions to the workshop.

This book covers relevant concepts in nuclear cardiology, combining imaging techniques and clinical data to do so. Today, nuclear cardiology is a worldwide discipline connected to the broader field of cardiovascular imaging. The combination of clinical aspects (symptoms, medications, previous cardiac procedures), ancillary exams and nuclear images is key to decision-making in clinical practice. Thus, a book on this topic is essential to provide better outcomes for cardiology patients. The chapters cover a comprehensive range of topics in current cardiology practice, such as ambulatory patients, patients in emergency settings, patients after complex cardiac procedures, and patients during and after the use of cancer therapies that are potentially toxic for the heart (cardio-oncology). As such, multiple clinical scenarios are also presented: patients with suspected coronary disease, patients with heart failure of unknown origin, patients with acute chest pain in the emergency department, patients with suspected pulmonary embolism, patients with complications of the left ventricular assist device, etc. Furthermore, the book describes nuclear cardiology procedures and techniques, discusses the main clinical indications and scenarios for each procedure, presents new technological advances in the field (machine learning and artificial intelligence tools), and mentions the coronavirus disease 2019 (COVID-19) pandemic. Given its scope, the book offers a valuable guide and videos for various medical professionals, especially cardiologists and nuclear physicians.

This must-have text provides an insight into the science behind radiographic technology. Suitable for radiography and radiology students at all levels, the text uses illustrations and simple analogies to explain the fundamentals, while retaining more complex concepts for those with a more advanced knowledge of radiological physics. Updated by authors Martin Vosper, Andrew England and Victoria Major to reflect advances and key topics in medical imaging practice, this text will support radiographers in their core role of obtaining high quality images and optimal treatment outcomes. Strong links between theory and practice throughout, with updated clinical scenarios Clear and concise text featuring insight boxes and summary points More than 60 new diagrams Logically organised to match the order of delivery used in current teaching programmes Updated to reflect advances in medical imaging practice and changes to teaching curricula New information on X-ray exposure factors and their effect on the radiographic image; non-ionising radiation safety - MRI, ultrasound; mobile, portable and dental systems; multimodality imaging, registration and fusion; and the science of body tissue depiction; and PACS technology Enhanced focus on diagnostic imaging Evolve resources to support learning and teaching

This book constitutes the Second Automatization of Cranial Implant Design in Cranioplasty Challenge, AutoImplant 2021, which was held in conjunction with the 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021, in Strasbourg, France, in September, 2021. The challenge took place virtually due to the COVID-19 pandemic. The 7 papers are presented together with one invited paper, one qualitative evaluation criteria from neurosurgeons and a dataset descriptor. This challenge aims to provide more affordable, faster, and more patient-friendly solutions to the design and manufacturing of medical implants, including cranial implants, which is needed in order to repair a defective skull from a brain tumor surgery or trauma. The presented solutions can serve as a good benchmark for future publications regarding 3D volumetric shape learning and cranial implant design.

This book constitutes the refereed joint proceedings of the 11th International Workshop on Multimodal Learning for Clinical Decision Support, ML-CDS 2021, held in conjunction with the 24th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2021, in Strasbourg, France, in October 2021. The workshop was held virtually due to the COVID-19 pandemic.The 10 full papers presented at ML-CDS 2021 were carefully reviewed and selected from numerous submissions. The ML-CDS papers discuss machine learning on multimodal data sets for clinical decision support and treatment planning.

This book constitutes the refereed proceedings of the Third International Workshop on Uncertainty for Safe Utilization of Machine Learning in Medical Imaging, UNSURE 2021, and the 6th International Workshop on Preterm, Perinatal and Paediatric Image Analysis, PIPPI 2021, held in conjunction with MICCAI 2021. The conference was planned to take place in Strasbourg, France, but was held virtually due to the COVID-19 pandemic.For UNSURE 2021, 13 papers from 18 submissions were accepted for publication. They focus on developing awareness and encouraging research in the field of uncertainty modelling to enable safe implementation of machine learning tools in the clinical world. PIPPI 2021 accepted 14 papers from the 18 submissions received. The workshop aims to bring together methods and experience from researchers and authors working on these younger cohorts and provides a forum for the open discussion of advanced image analysis approaches focused on the analysis of growth and development in the fetal, infant and paediatric period.

The eight-volume set LNCS 12901, 12902, 12903, 12904, 12905, 12906, 12907, and 12908 constitutes the refereed proceedings of the 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021, held in Strasbourg, France, in September/October 2021.*The 531 revised full papers presented were carefully reviewed and selected from 1630 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: image segmentation Part II: machine learning - self-supervised learning; machine learning - semi-supervised learning; and machine learning - weakly supervised learning Part III: machine learning - advances in machine learning theory; machine learning - attention models; machine learning - domain adaptation; machine learning - federated learning; machine learning - interpretability / explainability; and machine learning - uncertainty Part IV: image registration; image-guided interventions and surgery; surgical data science; surgical planning and simulation; surgical skill and work flow analysis; and surgical visualization and mixed, augmented and virtual reality Part V: computer aided diagnosis; integration of imaging with non-imaging biomarkers; and outcome/disease prediction Part VI: image reconstruction; clinical applications - cardiac; and clinical applications - vascular Part VII: clinical applications - abdomen; clinical applications - breast; clinical applications - dermatology; clinical applications - fetal imaging; clinical applications - lung; clinical applications - neuroimaging - brain development; clinical applications - neuroimaging - DWI and tractography; clinical applications - neuroimaging - functional brain networks; clinical applications - neuroimaging - others; and clinical applications - oncology Part VIII: clinical applications - ophthalmology; computational (integrative) pathology; modalities - microscopy; modalities - histopathology; and modalities - ultrasound *The conference was held virtually.

The eight-volume set LNCS 12901, 12902, 12903, 12904, 12905, 12906, 12907, and 12908 constitutes the refereed proceedings of the 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021, held in Strasbourg, France, in September/October 2021.*The 531 revised full papers presented were carefully reviewed and selected from 1630 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: image segmentation Part II: machine learning - self-supervised learning; machine learning - semi-supervised learning; and machine learning - weakly supervised learning Part III: machine learning - advances in machine learning theory; machine learning - attention models; machine learning - domain adaptation; machine learning - federated learning; machine learning - interpretability / explainability; and machine learning - uncertainty Part IV: image registration; image-guided interventions and surgery; surgical data science; surgical planning and simulation; surgical skill and work flow analysis; and surgical visualization and mixed, augmented and virtual reality Part V: computer aided diagnosis; integration of imaging with non-imaging biomarkers; and outcome/disease prediction Part VI: image reconstruction; clinical applications - cardiac; and clinical applications - vascular Part VII: clinical applications - abdomen; clinical applications - breast; clinical applications - dermatology; clinical applications - fetal imaging; clinical applications - lung; clinical applications - neuroimaging - brain development; clinical applications - neuroimaging - DWI and tractography; clinical applications - neuroimaging - functional brain networks; clinical applications - neuroimaging - others; and clinical applications - oncology Part VIII: clinical applications - ophthalmology; computational (integrative) pathology; modalities - microscopy; modalities - histopathology; and modalities - ultrasound *The conference was held virtually.

The eight-volume set LNCS 12901, 12902, 12903, 12904, 12905, 12906, 12907, and 12908 constitutes the refereed proceedings of the 24th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2021, held in Strasbourg, France, in September/October 2021.*The 531 revised full papers presented were carefully reviewed and selected from 1630 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: image segmentation Part II: machine learning - self-supervised learning; machine learning - semi-supervised learning; and machine learning - weakly supervised learning Part III: machine learning - advances in machine learning theory; machine learning - attention models; machine learning - domain adaptation; machine learning - federated learning; machine learning - interpretability / explainability; and machine learning - uncertainty Part IV: image registration; image-guided interventions and surgery; surgical data science; surgical planning and simulation; surgical skill and work flow analysis; and surgical visualization and mixed, augmented and virtual reality Part V: computer aided diagnosis; integration of imaging with non-imaging biomarkers; and outcome/disease prediction Part VI: image reconstruction; clinical applications - cardiac; and clinical applications - vascular Part VII: clinical applications - abdomen; clinical applications - breast; clinical applications - dermatology; clinical applications - fetal imaging; clinical applications - lung; clinical applications - neuroimaging - brain development; clinical applications - neuroimaging - DWI and tractography; clinical applications - neuroimaging - functional brain networks; clinical applications - neuroimaging - others; and clinical applications - oncology Part VIII: clinical applications - ophthalmology; computational (integrative) pathology; modalities - microscopy; modalities - histopathology; and modalities - ultrasound *The conference was held virtually.