This book provides structured up-to-date information on all routine protocols used for multislice (multidetector row) CT. The volume contains a detailed technical section and covers the prevailing investigations of the brain, neck, lungs and chest, abdomen with parenchymal organs and gastrointestinal tract, the musculoskeletal system and CTA as well as dedicated protocols for the heart. Separate chapters address the how-to of CT-guided interventions such as punctures, drainages, and therapeutic approaches. Each protocol is displayed en bloc, enabling rapid appreciation of indications and the necessary scanner settings.

The second edition includes contributions by renowned experts in the field, who not only provide their clinical experience on each topic, but also give guidelines for indications, workflow, postprocessing and reconstruction algorithms.

Interventional cardiology has transitioned from angiographic subjective analysis of stenosis severity into assessment of plaque characteristics and objective assessment of stenosis severity. The evolution of novel interventional imaging modalities is progressively altering our understanding of coronary artery disease diagnosis and prognosis. This book will be an essential companion to assist interventional cardiologists in better assessing patients with Coronary Artery Disease. It will encompass and review all interventional imaging modalities and provide guidance for interventional cardiologists to use these modalities.

The use of more robust, affordable, and efficient techniques and technologies in the application of medicine is presently a subject of huge interest and demand. Technology and Medical Sciences solidifies knowledge in the fields of technology and medical sciences and to define their key stakeholders. The book is designed for academics in engineering, mathematics, medicine, biomechanics, computation sciences, hardware development and manufacturing, electronics and instrumentation, and materials science.

This issue of Neuroimaging Clinics of North America focuses on Temporal Bone Imaging: Clinicoradiologic and Surgical Considerations, and is edited by Drs. Gul Moonis and Amy Fan-Yee Juliano. Articles will include: Imaging of Temporal Bone Infection Inflammation; Imaging of Meniere's Disease; Treatment of Vestibular Schwannoma; Post Operative Imaging of the Temporal Bone; Otosclerosis and Dysplasias of the Temporal Bone; Imaging of Syndromes with Temporal Bone Abnormalities; Imaging of Third Window Lesions; Imaging of Tinnitus; Imaging of Temporal Bone Tumors; Imaging of Pediatric Hearing Loss; Common Otologic Surgical Procedures: Clinical Decision Making Pearls; Imaging of Temporal Bone Trauma: A Clinicoradiologic Perspective; and more!

Developing an effective computer-aided diagnosis (CAD) system for lung cancer is of great clinical importance and can significantly increase the patient's chance for survival. For this reason, CAD systems for lung cancer have been investigated in a large number of research studies. A typical CAD system for lung cancer diagnosis is composed of four main processing steps: segmentation of the lung fields, detection of nodules inside the lung fields, segmentation of the detected nodules, and diagnosis of the nodules as benign or malignant. This book overviews the current state-of-the-art techniques that have been developed to implement each of these CAD processing steps. Overviews the latest state-of-the-art diagnostic CAD systems for lung cancer imaging and diagnosis Offers detailed coverage of 3D and 4D image segmentation Illustrates unique fully automated detection systems coupled with 4D Computed Tomography (CT) Written by authors who are world-class researchers in the biomedical imaging sciences Includes extensive references at the end of each chapter to enhance further study Ayman El-Baz is a professor, university scholar, and chair of the Bioengineering Department at the University of Louisville, Louisville, Kentucky. He earned his bachelor's and master's degrees in electrical engineering in 1997 and 2001, respectively. He earned his doctoral degree in electrical engineering from the University of Louisville in 2006. In 2009, he was named a Coulter Fellow for his contributions to the field of biomedical translational research. He has 17 years of hands-on experience in the fields of bio-imaging modeling and noninvasive computer-assisted diagnosis systems. He has authored or coauthored more than 500 technical articles (132 journals, 23 books, 57 book chapters, 211 refereed-conference papers, 137 abstracts, and 27 U.S. patents and disclosures). Jasjit S. Suri is an innovator, scientist, a visionary, an industrialist, and an internationally known world leader in biomedical engineering. He has spent over 25 years in the field of biomedical engineering/devices and its management. He received his doctorate from the University of Washington, Seattle, and his business management sciences degree from Weatherhead School of Management, Case Western Reserve University, Cleveland, Ohio. He was awarded the President's Gold Medal in 1980 and named a Fellow of the American Institute of Medical and Biological Engineering for his outstanding contributions in 2004. In 2018, he was awarded the Marquis Life Time Achievement Award for his outstanding contributions and dedication to medical imaging and its management.

This book introduces the latest optical coherence tomography (OCT) imaging and computerized automatic image analysis techniques, and their applications in the diagnosis and treatment of retinal diseases. Discussing the basic principles and the clinical applications of OCT imaging, OCT image preprocessing, as well as the automatic detection and quantitative analysis of retinal anatomy and pathology, it includes a wealth of clinical OCT images, and state-of-the-art research that applies novel image processing, pattern recognition and machine learning methods to real clinical data. It is a valuable resource for researchers in both medical image processing and ophthalmic imaging.

With collaboration of Dr. Alan Buchman, Consulting Editor, Dr. Perry J. Pickhardt has created a comprehensive issue of Gastroenterology Clinics that looks at imaging techniques for gastrointestinal diseases. Experts in their respective fields have contributed clinical reviews in the following areas: Evaluation of Dysphagia: The Role of Barium Fluoroscopy; CT and MR Small Bowel Enterography: Current Status and Future Trends; Radiologic Assessment of Gastrointestinal Bleeding; CT Colonography: Implementation for Screening; Rectal MR for Cancer Staging and Surveillance; Defecography (fluoro vs MR); Noninvasive Imaging Techniques for Staging Liver Fibrosis; HCC Screening: Comparison of US, CT, and MR Approaches; Pancreatic Cystic Lesions; Overview of biliary imaging; Splenomegaly: Clinico-Radiologic Approach to the Differential Diagnosis; MR for Non-Traumatic Acute Abdominal Pain: Comparison with CT and US; and PET/MR: Current Clinical Status and Future Prospects. Gastroenterologists will come away with the knowledge they need to understand the latest imaging modalities for diagnosis and assessment of gastrointestinal diseases and disorders.

Dentistry is a branch of medicine with its own particularities and very different fields of action, and is generally regarded as an interdisciplinary field. The use of new technologies is currently the main driving force for the series of international conferences on Biodental Engineering (BIODENTAL). BIODENTAL ENGINEERING V contains the full papers presented at the 5th International Conference on Biodental Engineering (BIODENTAL 2018, Porto, Portugal, 22-23 June 2018). The conference had two workshops, one of them dealing with computational imaging combined with finite element method, the other dealing with bone tissue remodelling models. Additionally, the conference had three special sessions and sixty contributed presentations. The topics discussed in BIODENTAL ENGINEERING V include: Aesthetics Bioengineering Biomaterials Biomechanical disorders Biomedical devices Computational bio- imaging and visualization Computational methods Dental medicine Experimental mechanics Signal processing and analysis Implantology Minimally invasive devices and techniques Orthodontics Prosthesis and orthosis Simulation Software development Telemedicine Tissue engineering Virtual reality The purpose of the series of BIODENTAL Conferences on Biodental Engineering, initiated in 2009, is to perpetuate knowledge on bioengineering applied to dentistry, by promoting a comprehensive forum for discussion on recent advances in related fields in order to identify potential collaboration between researchers and end-users from different sciences.

This issue of Interventional Cardiology Clinics, edited by Jorge Gonzalez and Matthew Price, will span a number of essential topics surrounding Imaging in Intervention. Subjects discussed include: Multimodality Imaging for Transcatheter Mitral Valve Replacement; CT Assessment for Transcatheter Aortic Valve Replacement; Imaging Evaluation and Interpretation for Vascular Access for TAVR; Imaging Evaluation for the Detection of Leaflet Thrombosis after TAVR; CT Imaging Guidance for WATCHMAN LAA Closure; Myocardial viability testing to guide coronary revascularization; Intravascular Ultrasound For Guidance and Optimization of Percutaneous Coronary Intervention; CT-FFR to guide coronary angiography and intervention; Multimodality imaging of the tricuspid valve for assessment and guidance of transcatheter repair; and Three-dimensional printing for structural heart intervention planning, among others.

Introduction to Electrophysiological Methods and Instrumentation, Second Edition covers all topics of interest to electrophysiologists, neuroscientists and neurophysiologists, from the reliable penetration of cells and the behavior and function of the equipment, to the mathematical tools available for analyzing data. It discusses the pros and cons of techniques and methods used in electrophysiology and how to avoid pitfalls. Although the basics of electrophysiological techniques remain the principal purpose of this second edition, it now integrates several current developments, including, amongst others, automated recording for high throughput screening and multimodal recordings to correlate electrical activity with other physiological parameters collected by optical means. This book provides the electrophysiologist with the tools needed to understand his or her equipment and how to acquire and analyze low-voltage biological signals.

The articles collected in this volume are based on lectures given at the IMA Workshop, "Computational Radiology and Imaging: Therapy and Diagnostics," March 17-21, 1997. Introductory articles by the editors have been added. The focus is on inverse problems involving electromagnetic radiation and particle beams, with applications to X-ray tomography, nuclear medicine, near-infrared imaging, microwave imaging, electron microscopy, and radiation therapy planning. Mathematical and computational tools and models which play important roles in this volume include the X-ray transform and other integral transforms, the linear Boltzmann equation and, for near-infrared imaging, its diffusion approximation, iterative methods for large linear and non-linear least-squares problems, iterative methods for linear feasibility problems, and optimization methods. The volume is intended not only for mathematical scientists and engineers working on these and related problems, but also for non-specialists. It contains much introductory expository material, and a large number of references. Many unsolved computational and mathematical problems of substantial practical importance are pointed out.

This book contains invited lecturers and full papers presented at VIPIMAGE 2011 - III ECCOMAS Thematic Conference on Computational Vision and Medical Image Processing (Olhao, Algarve, Portugal, 12-14 October 2011). International contributions from 16 countries provide a comprehensive coverage of the current state-of-the-art in: Image Processing and Analysis; Tracking and Analyze Objects in Images; Segmentation of Objects in Images; 3D Vision; Signal Processing; Data Interpolation, Registration, Acquisition and Compression; Objects Simulation; Medical Imaging; Virtual Reality; Software Development for Image Processing and Analysis; Computer Aided Diagnosis, Surgery, Therapy and Treatment; Computational Bioimaging and Visualization; Telemedicine Systems and their Applications. Related techniques also covered in this book include the level set method, finite element method, modal analyses, stochastic methods, principal and independent components analyses and distribution models. Computational Vision and Medical Image Processing - VIPIMAGE 2011 will be useful to academics, researchers and professionals in Computational Vision (Image Processing and Analysis), Computer Sciences, Computational Mechanics and Medicine.

Intracoronary ultrasound is a rapidly evolving imaging modality and the increasing number of published studies indicates that the technique is safe and provides incremental and more detailed diagnostic information than coronary angiography. The technique has the potential to study the pathobiology of atherosclerosis, to clarify the significance of angiographically equivocal lesions and has helped us to understand the mechanisms, effects and complications of catheter-based revascularization procedures. Combinations of imaging and therapeutic devices are being developed for both guidance and assessment of the revascularization procedure. Three-dimensional reconstruction of coronary segments is now possible in real time and provides the opertor with more detailed information on coronary pathology. In this monograph, leading experts in the field present the state of the art of all these new developments.

Dr. Leonard Swischuk, who is recognized for authoring several superb and widely read pediatric radiology textbooks, has produced yet another outstanding work on the important subject of imaging the cervical spine in children. A distinguished pediatric radiologist, he draws upon his extensive experience in the field and his gift for writing clear and readable text to provide practitioners with an insightful approach to pediatric cervical spine injuries. Those who work in trauma imaging will appreciate the wealth of practical guidelines contained in this thorough yet concise book. Dr. Swischuk's text is organized into six chapters. The first two discuss developmental anatomy and normal variants. Chapters three and four concentrate on congenital anomalies and on abnormalities of the dens. The final two chapters consider trauma and miscellaneous abnormalities of the cervical spine. The book has several notable strengths that are appealing to radiology residents, such as its succinct and well-organized overview of the topic. To help residents identify cases that they are likely to encounter during board exams and in practice, Dr. Swischuk selected excellent plain film examples from his personal collection that illustrate the conditions he discusses and reflect his emphasis on cervical radiography. The illustrated cases also include CT and MR images that clarify and qualify the plain film findings. Helpful reference lists complete each chapter and guide residents to resources for further reading. In addition, Dr. Swischuk 's direct writing style makes the complex content highly accessible, providing imaging residents with an invaluable introduction to pediatric cervical spine radiology.

This book provides a perspective on the current status of bioimaging technologies developed to assess the quality of musculoskeletal tissue with an emphasis on bone and cartilage. It offers evaluations of scaffold biomaterials developed for enhancing the repair of musculoskeletal tissues. These bioimaging techniques include micro-CT, nano-CT, pQCT/QCT, MRI, and ultrasound.

High Efficiency Video Coding and Other Emerging Standards provides an overview of high efficiency video coding (HEVC) and all its extensions and profiles. There are nearly 300 projects and problems included, and about 400 references related to HEVC alone. Next generation video coding (NGVC) beyond HEVC is also described. Other video coding standards such as AVS2, DAALA, THOR, VP9 (Google), DIRAC, VC1, and AV1 are addressed, and image coding standards such as JPEG, JPEG-LS, JPEG2000, JPEG XR, JPEG XS, JPEG XT and JPEG-Pleno are also listed. Understanding of these standards and their implementation is facilitated by overview papers, standards documents, reference software, software manuals, test sequences, source codes, tutorials, keynote speakers, panel discussions, reflector and ftp/web sites - all in the public domain. Access to these categories is also provided.

Better understand and retain the material in Kelley's Sectional Anatomy for Imaging Professionals, 4th Edition with this dynamic workbook. With its wide variety of engaging exercises - including illustration labeling, puzzles, case studies, matching activities, fill-in-the-blank questions, short-answer questions, and more - you can benefit from an integrated and highly-visual approach to learning sectional anatomy and its application in diagnostic imaging. Wide variety of engaging exercises - including matching, true/false, fill-in-the-blank, case studies, and labeling - aid your learning and retention. Chapter objectives focus your attention on the important concepts you are expected to master by the end of the chapter. Memory learning aids help you quickly memorize terms, definitions, and anatomic locations so you can concentrate more on the application of concepts. Over 300 images with labeling opportunities provide thorough practice in identifying anatomic structures. NEW! Updated material corresponds with the updated material in the main text. NEW! Additional labeling queries reinforce identification of structures on sectional anatomy images. NEW! Additional exercises further emphasize anatomic location and function. NEW! Additional case studies help tie the material to what happens on the job in the clinical setting.

Imaging Genetics presents the latest research in imaging genetics methodology for discovering new associations between imaging and genetic variables, providing an overview of the state-of the-art in the field. Edited and written by leading researchers, this book is a beneficial reference for students and researchers, both new and experienced, in this growing area. The field of imaging genetics studies the relationships between DNA variation and measurements derived from anatomical or functional imaging data, often in the context of a disorder. While traditional genetic analyses rely on classical phenotypes like clinical symptoms, imaging genetics can offer richer insights into underlying, complex biological mechanisms.

"This book presents the technology evaluation methodology from the point of view of radiological physics and contrasts the purely physical evaluation of image quality with the determination of diagnostic outcome through the study of observer performance. The reader is taken through the arguments with concrete examples illustrated by code in R, an open source statistical language." - from the Foreword by Prof. Harold L. Kundel, Department of Radiology, Perelman School of Medicine, University of Pennsylvania "This book will benefit individuals interested in observer performance evaluations in diagnostic medical imaging and provide additional insights to those that have worked in the field for many years." - Prof. Gary T. Barnes, Department of Radiology, University of Alabama at Birmingham This book provides a complete introductory overview of this growing field and its applications in medical imaging, utilizing worked examples and exercises to demystify statistics for readers of any background. It includes a tutorial on the use of the open source, widely used R software, as well as basic statistical background, before addressing localization tasks common in medical imaging. The coverage includes a discussion of study design basics and the use of the techniques in imaging system optimization, memory effects in clinical interpretations, predictions of clinical task performance, alternatives to ROC analysis, and non-medical applications. Dev P. Chakraborty, PhD, is a clinical diagnostic imaging physicist, certified by the American Board of Radiology in Diagnostic Radiological Physics and Medical Nuclear Physics. He has held faculty positions at the University of Alabama at Birmingham, University of Pennsylvania, and most recently at the University of Pittsburgh.

This volume provides a comprehensive overview of quality metrics and methods used to improve quality for all major modalities of CRC screening. It introduces the readers to the evidence of effectiveness behind various CRC screening modalities: stool-based tests (Fecal Occult Blood, Fecal Immunochemical and Fecal DNA tests), flexible sigmoidoscopy, colonoscopy and CT colonography. In-depth chapters review the latest guidelines for CRC screening, compare differences among the five major national guidelines, and highlight the need for valid quality and cost indicators. While the main focus of this volume is on colonoscopy, since most quality indicators and analyses have focused on this modality of screening and surveillance, one chapter is devoted to quality indicators of other screening modalities. Differences between process and outcome measures are also highlighted and a small but valid set of recommended national measures are listed. Written by experts in the field, Colorectal Cancer Screening: Quality and Benchmarks is an important and useful resource written for gastroenterologists, primary care physicians, general and colorectal surgeons, family physicians, and investigators with research focus in screening and quality metrics.

This comprehensive reference work details the latest developments in fluorescence imaging and related biological quantification. It explores the most recent techniques in this imaging technology through the utilization and incorporation of quantification analysis which makes this book unique. It also covers super resolution microscopy with the introduction of 3D imaging and high resolution fluorescence. Many of the chapter authors are world class experts in this medical imaging technology.

Diagnostic imaging is an essential component in the evaluation of the patient with known or suspected respiratory tract disease. While chest radiography continues to serve as the primary tool for imaging the chest, advances in computed tomography (CT) have led to a variety of applications such as high-resolution CT (HRCT), advanced 3-D airway imaging, and image-guided procedures. The aim of this book is to deliver a clinically-oriented approach to pulmonary imaging. Each chapter of the book will provide an organized approach to the different facets of imaging of specific clinical scenarios, focusing on strengths and weaknesses of available imaging tests. High quality examples of typical imaging findings of specific conditions will supplement the text. The target readers include practicing internists, pulmonologists, thoracic surgeons, and primary care practitioners. Other readers will include respiratory care therapists and medical students. The proposed cohort of authors represents experts in the field of thoracic radiology. These authors have experience in thoracic radiology and medical writing, each will deliver a high-quality chapter meeting the aims and scope of this book while addressing the target audience. Aside from the first three chapters, which are introductory materials, each author will be invited to select a clinician with whom they work closely to serve as a co-author in order to provide a chapter that maintains the clinical orientation of this book.

With the increasing interest in the experimental and clinical application of molecular imaging many institutions create research groups or interdisciplinary centers focussing on the complex development process of this new methodology. The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Finding the Nerve: The Story of Impedance Neurography discusses research that elucidates the nature of nerve simulation via externally applied electrical fields, and how it has led to an entirely new understanding of neuronal cell membrane biophysics and defined a novel nerve imaging technology. It details how these discoveries came about and the nature of research that derives from unexplained clinical observations. The primary technology, impedance neurography, is a wholly new way of nerve-specific visualization in 2-D or 3-D, with the ability to define both normal and abnormal functioning of nerves, heretofore unavailable from techniques such as MRI neurography. This is of particular importance with respect to the obesity epidemic where physicians performing nerve-related procedures cannot use ultrasound visualization due to the depth limitations of that technology.

This issue of Neuroimaging Clinics of North America focuses on Imaging of Multiple Sclerosis: Diagnosis and Management, and is edited by Dr. Alex Rovira Canellas. Articles will include: Multiple Sclerosis: Epidemiological, Clinical and Therapeutic Aspects; Brain and Spinal Cord MR Imaging Features in Multiple Sclerosis and Variants; Neuromyelitis Optica Spectrum Disorders; Radiologically Isolated Syndrome; MRI in Monitoring and Predicting Treatment Response in Multiple Sclerosis; Cortical Grey Matter MR Imaging in Multiple Sclerosis; Brain Atrophy in Multiple Sclerosis: Technical Aspects and Clinical Relevance; Iron Mapping in Multiple Sclerosis; Microstructural MR Techniques in Multiple Sclerosis; Molecular and Metabolic Imaging in Multiple Sclerosis; Insights from Ultra-high Field Imaging in Multiple Sclerosis; Pediatric Multiple Sclerosis: Distinguishing Clinical and MRI Features, and more!