Optical imaging is a rapidly emerging imaging technique that has been successfjully translated into biomedical applications ranging from clinical diagnosis to molecular biology. This book includes an introductory section to explore various optical imaging devices and their functionality and roles for biomedical applications such as dermatology and ophthalmology. Recent developments as exemplified with the authors research are explored in detail. In depth discussion of other disease conditions and their diagnosis with optical imaging techniques are also covered.

The third edition of Carvers' Medical Imaging supports radiography students to take a reflective, evidence-based approach that will enhance their practice. This important textbook comprehensively covers the full range of medical imaging methods and techniques in one volume, and discusses them in relation to imaging principles, radiation dose, patient condition, body area and pathologies. It encourages the student to critically analyse their work rather than simply carrying out tasks. The book has been updated by an impressive team of contributors to align with developments in both radiographic techniques and the role of the radiographer. It is an essential companion for students of BSc (Hons) diagnostic radiography, those undertaking a foundation degree in radiographic practice or bachelor of medicine, and postgraduates alike. Comprehensive, fully illustrated and well referenced discussion of all imaging techniques. Full image evaluation for radiographic examinations, including common errors New material on potential impact of errors on accuracy of the radiographic report New sections on preliminary clinical evaluation for projection radiography examinations, which prepares students for UK professional standards Section on cross infection implications (relevant post COVID-19) Includes imaging of children with suspected physical abuse

The first in a three-volume set exploring Problems and Solutions in Medical Physics, this volume explores common questions and their solutions in Diagnostic Imaging. This invaluable study guide should be used in conjunction with other key textbooks in the field to provide additional learning opportunities. It contains key imaging modalities, exploring X-ray, mammography, and fluoroscopy, in addition to computed tomography, magnetic resonance imaging, and ultrasonography. Each chapter provides examples, notes, and references for further reading to enhance understanding. Features: Consolidates concepts and assists in the understanding and applications of theoretical concepts in medical physics Assists lecturers and instructors in setting assignments and tests Suitable as a revision tool for postgraduate students sitting medical physics, oncology, and radiology sciences examinations

Soft Computing Based Medical Image Analysis presents the foremost techniques of soft computing in medical image analysis and processing. It includes image enhancement, segmentation, classification-based soft computing, and their application in diagnostic imaging, as well as an extensive background for the development of intelligent systems based on soft computing used in medical image analysis and processing. The book introduces the theory and concepts of digital image analysis and processing based on soft computing with real-world medical imaging applications. Comparative studies for soft computing based medical imaging techniques and traditional approaches in medicine are addressed, providing flexible and sophisticated application-oriented solutions.

Cerebral Dural Arteriovenous Fistulas serves as an authoritative, comprehensive resource for these vascular lesions, describing their anatomy, diagnosis, natural history, and thorough treatment options. Rooted in well-illustrated anatomy and depictions of dAVFs, readers can better understand their pathophysiology, historical discovery, and avenues for treatment, including embolization, surgery, and radiosurgery. Imaging modalities are also discussed extensively as well as the management of these lesions. This reference is appropriate for neurosurgeons, neurologists, interventional radiologists and intensivists that manage these patients, providing clarity, and at the same time, comprehensiveness.

Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy, electron microscopy, molecular dynamics simulations and nuclear magnetic resonance. Each method is explained in detail using examples of real-world applications. Short asides are provided throughout to ensure that explanations are accessible to life scientists, physicists and those with medical backgrounds. The book remains an unparalleled and comprehensive resource for graduate students of biophysics and medical physics in science and medical schools, as well as for research scientists looking for an introduction to techniques from across this interdisciplinary field.

Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

Reflecting recent major advances in the field of artificial intelligence, Developing the Digital Lung, From First Lung CT to Clinical AI, by Dr. John Newell, is your go-to reference for all aspects of applied artificial intelligence in lung disease development, including application to clinical medicine. It provides a unique overview of the field, beginning with a review of the origins of artificial intelligence in the mid-1970s and progressing to its application to clinical medicine in the early 2020s. Organized based on the four stages of development, this practical, easy-to-use resource helps you effectively apply artificial intelligences to lung imaging. Traces the development of precise quantitative CT of diffuse lung disease through the use of applied AI, leading to faster effective diagnosis of patients with lung disease. Reviews CT manufacturers, models and scanning protocol used to produce the 3D digital maps of the lungs. Discusses how the data processed by AI algorithms can produce measures of emphysema, air trapping, and airway wall thickening in subjects with COPD and measures of pulmonary fibrosis and traction bronchiectasis in idiopathic pulmonary fibrosis (IPF). Demonstrates the differences between reactive machine AI and limited memory AI methods. Includes comprehensive case studies and current information on cloud computing. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Dermoscopy is a noninvasive skin imaging technique that uses optical magnification and either liquid immersion or cross-polarized lighting to make subsurface structures more easily visible when compared to conventional clinical images. It allows for the identification of dozens of morphological features that are particularly important in identifying malignant melanoma. Dermoscopy Image Analysis summarizes the state of the art of the computerized analysis of dermoscopy images. The book begins by discussing the influence of color normalization on classification accuracy and then: Investigates gray-world, max-RGB, and shades-of-gray color constancy algorithms, showing significant gains in sensitivity and specificity on a heterogeneous set of images Proposes a new color space that highlights the distribution of underlying melanin and hemoglobin color pigments, leading to more accurate classification and border detection results Determines that the latest border detection algorithms can achieve a level of agreement that is only slightly lower than the level of agreement among experienced dermatologists Provides a comprehensive review of various methods for border detection, pigment network extraction, global pattern extraction, streak detection, and perceptually significant color detection Details a computer-aided diagnosis (CAD) system for melanomas that features an inexpensive acquisition tool, clinically meaningful features, and interpretable classification feedback Presents a highly scalable CAD system implemented in the MapReduce framework, a novel CAD system for melanomas, and an overview of dermatological image databases Describes projects that made use of a publicly available database of dermoscopy images, which contains 200 high-quality images along with their medical annotations Dermoscopy Image Analysis not only showcases recent advances but also explores future directions for this exciting subfield of medical image analysis, covering dermoscopy image analysis from preprocessing to classification.

This issue of Surgical Oncology Clinics of North America, devoted to Imaging in Oncology, is edited by Dr. Vijay Khatri. Articles in this issue include: Imaging of Central Nervous Tumors; Role of Imaging in Head and Neck Malignancies; Imaging of Thoracic Cavity Tumor; Diagnostic Imaging of Hepatobiliary Malignancies; Recent Advances in Genito-Urinary Tract Tumors; Current Status of Imaging for Adrenal Glands; Radiology of Soft Tissue Tumors; Image-Guided Interventions in Oncology; Imaging of Pancreatic Neoplasms; Imaging of Primary Malignant Tumors of Peritoneal and Retroperitoneal Origin; Breast Tumor Imaging; and Application of Intraoperative Imaging in Oncology.

COMPUTED TOMOGRAPHY: PHYSICS AND TECHNOLOGY In the newly updated second edition of Computed Tomography: Physics and Technology A Self Assessment Guide, distinguished computed tomography (CT) educator Euclid Seeram delivers a completely revised and expanded collection of multiple-choice questions covering all relevant technological advances, including the use of artificial intelligence, in the field of CT. In the book, readers will find a focused emphasis on physics and technology -- an area where students of this discipline have traditionally struggled. The questions are presented in a format similar to those found on the certification examinations of the American Registry of Radiologic Technologists (ARRT), the Canadian Association of Medical Radiation Technologists (CAMRT), and other professional medical imaging organizations around the world. The author has also included true-false questions, short answer questions, and relevant learning outcomes to aid students in their study of the subject. Readers will also find brief notes on: An introduction to computed tomography, including an overview of the field and a historical perspective Digital image processing and the physics of computed tomography Data acquisition principles and technology and image reconstruction fundamentals Deep learning image reconstruction, the major equipment components of a computed tomography scanner, and image post-processing and visualization Multislice CT: Principles and Technology Image quality considerations CT Dosimetry and dose optimization strategies Quality control Perfect for radiological technology and diagnostic radiography students and practitioners, Computed Tomography: Physics and Technology A Self Assessment Guide, will also earn a place in the libraries of biomedical engineering students and radiology residents in training.

This book is an indispensable reference for pediatric and musculoskeletal radiologists, as well as orthopedic surgeons. It offers in depth analysis of pediatric orthopedic imaging, covering normal and aberrant development as well as both common and unusual pediatric disorders. Chapters on the spine, shoulder, elbow, hand and wrist, hip and pelvis, lower extremity, and foot and ankle address site-specific congenital and acquired lesions. Subsequent chapters cover generalized orthopedic diseases such as neurofibromatosis and osteogenesis imperfecta, infectious processes, neuromuscular diseases, musculoskeletal tumors, trauma, and orthopedic procedures. The chapters review associated epidemiology, clinical presentation and evolution, treatment, and differential diagnoses, with in-depht analysis of imaging characteristics. With more than 1800 images, high-quality MRI, CT, and US examples complement the radiographs of a broad variety of musculoskeletal disorders.

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. "Imaging of the Human Brain in Health and Disease" examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases.

Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease.

This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease.
A focused introduction to imaging healthy and diseased brainsFocuses on the primary neurotransmitter releaseIncludes sigma, acetylcholine, opioid, and dopamine receptorsPresents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

CT, contrast CT, MRI, functional MRI, SPECT, CTA, and x-ray as tools to identify pathogens and diagnose intracranial infections are presented. Topics include: Epidemiology of Central Nervous System Infections; Imaging of Cranial Meningitis and Ventriculitis; Encephalitis, Cerebritis and Brain Abscess; Imaging of Central Nervous System Tuberculosis; Imaging of Rickettsial, Spirochetal, and Parasitic Infections; Imaging of Neurocysticercosis; Fungal Infections of the Central Nervous System; Central Nervous System Infections in the Pediatric Population; Imaging of Infectious Diseases of Spine; Neuropathological Findings in Intracranial Infections; Neurosurgical Approach to Infectious Disease of the Brain; Head and Neck Infections.

"Emergency Musculoskeletal Imaging in Children" is a practical, concise, and easy-to-read guide to the radiologic workup of acute musculoskeletal injuries and conditions in children. The book is conveniently organized by anatomic site and covers all acute injuries and conditions of the upper and lower extremities encountered in the emergency room, outpatient clinic, and office. Close attention is also given to normal findings and anatomic variants that can mimic pathology. More than 600 MR, CT, ultrasound, and radiographic images complement the text.

The fourth edition of Atlas of the Human Brain presents the anatomy of the brain at macroscopic and microscopic levels, featuring different aspects of brain morphology and topography. This greatly enlarged new edition provides the most detailed and accurate delineations of brain structure available. It includes features which assist in the new fields of neuroscience - functional imaging, resting state imaging and tractography. Atlas of the Human Brain is an essential guide to those working with human brain imaging or attempting to relate their observations on experimental animals to humans. Totally new in this edition is the inclusion of Nissl plates with delineation of cortical areas (Brodmann's areas), the first time that these areas have been presented in serial histological sections.

"Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study and treatment of neuropsychiatric disorders. "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. The focus of this book is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This book covers methodical issues in human and animal neuroimaging translational research as well as detailed applied examples of the use of neuroimaging in neuropsychiatric disorders and the development of drugs for their treatment. Offering an accompanying website with illustrations and text available for further knowledge and presentations, "Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment" appeals to non-clinical and clinical neuroscientists working in and studying neuropsychiatric disorders and their treatment as well as providing the novice researcher or researcher outside of his/her expertise the opportunity to understand the background of translational research and the use of imaging in this field.
Provides a background to translational research and the use of brain imaging in neuropsychiatric disordersCritical discussion of the potential and limitations of neuroimaging as a translational tool for identifying and validating biomarkersIdentifies cross species neurosystems and common endpoints necessary to help accelerate CNS drug discovery and development for the treatment of neuropsychiatric disordersFeatures an accompanying website with additional images and text

The imaging of small cellular components requires powerful instruments, and an entire family of equipment and techniques based on the confocal principle has been developed over the past 30 years. Such methods are commonly used by neuroscience researchers, but the majority of these users do not have a microscopy or a cell biology backgrounds and do can encounter difficulties in obtaining and interpreting results. This volume brings experts in high-resolution optical microscopy applications in neuroscience and cell biology together to document the state of the art. Outlining what is currently possible, the volume also discusses promising developments for the future and aids readers in selecting the most scientifically meaningful approach to solve their questions. Each chapter discusses instrumentation and technology in relationship to application in research. All of the common and cutting edge trends are covered - fluorescence / laser electron / nonlinear microscopy, infrared fluorescence, multiphoton imaging, tomography, FRAP, live imaging, STED, PALM/STORM, etc.
* Single and multiphoton confocal microscopy, and 4-pi confocal microscopy
* Obtaining nanoresolution via photoactivation localization microscopy (PALM)
* Several procedures that correlate observations in optical fluorescence microscopy and electron microscopy
* Study of morphology and function via high-resolution fluorescence procedures
* Additional high-resolution microscopic techniques

This volume of Methods in Enzymology is thethird of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
The third of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cellsThe chapters provide hints and tricks not available in primary research publicationsIt is an invaluable resource for academics, researchers and students alike"

This volume of Methods in Enzymology is the first of 3 parts looking at current methodology for the imaging and spectroscopic analysis of live cells. The chapters provide hints and tricks not available in primary research publications. It is an invaluable resource for academics, researchers and students alike.
Expert authors who are leaders in the fieldExtensively referenced and useful figures and tablesProvides hints and tricks to facilitate reproduction of methods

Engage with the visual world of disease with this accessible introduction to molecular imaging. This book provides users of all levels with the characterization and measurement of biological processes on a cellular level, functioning within humans, and other living systems. This important new introduction to the field will enable the reader to recognize the major methods, modalities and varied applications of molecular imaging in an efficient and effective way. Featuring techniques from areas such as nuclear medicine, magnetic resonance spectroscopy, optical imaging, and nanotechnology, the book also covers the current movement towards precision medicine thereby driving exceptional hospital care, worldwide. Molecular Imaging provides valuable insight into the properties that improve patient diagnosis. Serving to inform experienced physicians, students, and beginners alike, this convenient introduction is tailored to an individual with the desire to effectively grasp the basic concepts of molecular imaging, under the constraints of a busy professional career.

This book discusses the efficacy of nanomaterial-based X-rays enhancers against cancer therapy and imaging in both in vitro and in vivo systems. Also, synthesis, mechanism, and the related biological effects are given. Moreover, nanoparticle-based contrast agents to enhance the image quality are compiled. Finally, special nanoparticle-based contrast agents to enhance the contrast for targeted cancer therapy are covered and discussed.

Drawing together topics from a wide range of disciplines, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine. Internationally renowned researchers showcase topics ranging from the basic physical principles of magnetism to the detection and manipulation, synthesis protocols and natural occurrence of magnetic nanoparticles. Up-to-date examples of their clinical usage and research applications in the biomedical fields of sensing by diverse magnetic detection methods, in imaging by MRI and in therapeutic strategies such as hyperthermia, are also discussed, providing a thorough introduction to this rapidly developing field. Each chapter features questions with answers, highlighted definition boxes, and numerous illustrations which help readers grasp key concepts. Mathematical tools, together with key literature references, provide a strong underpinning for the material, making it ideal for graduate students, lecturers, medical researchers and industrial scientific strategists.

This book is designed to give the reader a strong grounding in the mathematical basis of photogrammetry while introducing them to the related fields, such as remote sensing and digital image processing, which are increasingly important to photogrammetric research and practice.

This textbook provides a comprehensive review of gynecological imaging in infancy, childhood, and adolescence. Experts from the disciplines of pediatric radiology, gynecology, surgery, and endocrinology have come together to produce a textbook that, while written primarily from the perspective of the radiologist, will be of interest to all professionals involved in the management of these patients. The normal development of the female reproductive tract is described in detail through embryological development, normal childhood appearances, and puberty. Congenital abnormalities are addressed in chapters reviewing structural abnormalities of the reproductive tract and disorders of sex development. A symptoms- based approach is followed in chapters devoted to the assessment of the patient with gynecological pain and disorders of menstruation. Disorders of the breast and the imaging of patients with gynecological neoplasia are considered in dedicated chapters. The specialty of pediatric gynecology is evolving rapidly, drawing on the skills and expertise of professionals from a wide range of specialties. This textbook should prove valuable to all who are involved in this new field of medicine.