This volume comprises of 21 selected chapters, including two overview chapters devoted to abdominal imaging in clinical applications supported computer aided diagnosis approaches as well as different techniques for solving the pectoral muscle extraction problem in the preprocessing part of the CAD systems for detecting breast cancer in its early stage using digital mammograms. The aim of this book is to stimulate further research in medical imaging applications based algorithmic and computer based approaches and utilize them in real-world clinical applications. The book is divided into four parts, Part-I: Clinical Applications of Medical Imaging, Part-II: Classification and clustering, Part-III: Computer Aided Diagnosis (CAD) Tools and Case Studies and Part-IV: Bio-inspiring based Computer Aided diagnosis techniques.

Imaging of Paranasal Sinuses is explored in this important Neuroimaging Clinics issue. Articles include: Current trends in sinonasal imaging; Normal anatomy and anatomic variants of the paranasal sinuses on CT; Pre-treatment imaging in inflammatory sinonasal disease; The role of CT and MRI in imaging of fungal sinusitis; Imaging approach to sinonasal tumors; The role of CT and MRI in imaging of sino-nasal tumors; The role of CT and MRI in the skull base in evaluation of sino-nasal disease; Post-treatment imaging of the paranasal sinuses following endoscopic sinus surgery; Post-treatment imaging of the paranasal sinuses following treatment for sinonasal neoplasia; and more!

The Guest Editors have assembled key opinion leaders to provide state of the art articles on this important update on ERCP. A chapter on cannulation techniques and sphincterotomy will highlight recent literature on wire-guided cannulation, use of papillotomes, when and if to precut for entry and the use of smart circuitry for papillotomy. A chapter on surgically altered anatomy will highlight the increasing occurrence of biliary tract disease in patient's s/p gastric bypass for obesity along with other surgery and the use of balloon enteroscopes, overtubes and intraoperative procedures A chapter on EUS assisted biliary and pancreatic access will highlight the growing experience with these combine techniques. There is growing literature on preventing post-ercp pancreatitis which is changing the standard of care and Joe Elmunzer is the best person to highlight this. Stu Sherman will review advances in the management of bile duct stones and when to intervene in gallstone pancreatitis. Peter Cotton just published a landmark study on SOD that will change the standard of care and will review the state of the science on this disease as it relates to both biliary tract and pancreatic disease. The management of benign biliary strictures and leaks is evolving with the introduction of covered metal stents and Jacques Deviere is at the forefront. Amrita Sethi will discuss diagnosis of biliary malignancy highlighting the use of FISH, molecular markers and enhanced imaging such as pCLE. Michele Kahaleh will review recent experience with biliary tumor ablation using RFA probes and PDT. Alan Barkun helps endoscopists determine when to use plastic stents, metal stents, and covered stents and when to drain one, two or three segments of liver in patients with malignant biliary obstruction. George Papachristo and Dhiraj Yadav will review most recent data on endoscopic therapy for acute recurrent and smoldering acute pancreatitis. Nagy Reddy will provide on update on endotherapy for painful chronic pancreatitis. Finally, Raj Shah will update on advances in pancreatoscopy and cholangioscopy including the use of ultra slim per-oral scopes and new digital mother/baby scopes.

Among the subjects reviewed in these Advances, the properties and computation of electromagnetic fields have been considered on several occasions. In particular, the early work of H.F. Harmuth on Maxwell's equations, which was highly controversial at the time, formed a supplement to the series
This volume, unlike previous volumes in the series concentrates solely on the research of professors' Harmuth and Meffert.
These studies raise important and fundamental questions concerning some of the basic areas of physics: electromagnetic theory and quantum mechanics. They deserve careful study and reflection for although the authors do not attempt to provide the definitive answer to the questions, their work is undoubtedly a major step towards such an answer. This volume essential reading for those researchers and academics working applied mathematicians or theoretical physics
Unlike previous volumes, this book concentrates solely on the new research of professors Harmuth and Meffert
Raises important and fundamental questions concerning electromagnetism theory and quantum mechanics
Provides the steps in finding answers for the highly debated questions

This issue of Interventional Cardiology Clinics, edited by Matthew J. Price, is devoted to Intravascular Imaging. Dr. Price assembled a group of expert contributors to review the following topics: IVUS for the assessment of coronary lesion severity and optimization of PCI; IVUS for the diagnosis and treatment of left main coronary artery disease; Fundamentals of OCT: image acquisition and interpretation; Technique and Best Practices for Intracoronary OCT; Assessment and quantitation of stent results by intracoronary OCT; PCI planning and optimization with intracoronary OCT; Advances in Automated Assessment of Intracoronary OCT and Their Clinical Application; Diagnosis and evaluation of stent thrombosis using OCT; Acute and long-term evaluation of bioresorbable scaffolds by OCT; Role of OCT in the diagnosis, evaluation, and management of spontaneous coronary artery dissection; and Neointimal Coverage after Drug-Eluting Stent Implantation: Insights from Optical Coherence Tomography.

Drs. Robert J. Lewandowski and Matthew S. Davenport have assembled an expert panel of authors on the topic of Interventional Radiology. Articles will include: Abdominal Biopsy: Technical and Clinical Considerations; Intra-arterial Therapies for Liver Masses; Liver Ablation: Best Practice; Renal Intervention; Imaging (Findings) after Intervention; Assessing Imaging Response to Therapy; Liver Masses: Imaging Evaluation in Non-cirrhotics; Imaging in Cirrhotics: Current Evidence; Renal Masses: Imaging Evaluation; Adrenal Imaging/Intervention; The Pancreas; and more!

Orbit and Neuro-ophthalmic Imaging is explored in this important Neuroimaging Clinics issue. Articles include: Imaging indication, protocols, anatomy, and pitfalls; Orbital ultrasonography and optical coherence tomography- what radiologists need to know; Advanced imaging techniques for the retina and visual pathway; Imaging of optic neuropathy and chiasmatic disorder; Imaging of post-chiasmatic disorder and higher cortical visual dysfunction; Imaging of diseases of the ocular motor pathway; Imaging of orbital trauma and emergent non-traumatic conditions; Imaging of ocular prosthesis and orbital reconstruction flaps; Imaging of pediatric ophthalmologic conditions; and more!

This issue of Cardiac Electrophysiology Clinics examines Frontiers in Non-invasive Cardiac Mapping. Topics include imaging of heart rhythm disorders, experimental validation and modeling of validation, challenges and future directions of inverse problems, phase mapping of cardiac fibrillation, frequency domain analysis, analysis of diagnostic 12-lead electrocardiography and 3D non-invasive mapping, and many more.

This issue of Clinics in Chest Medicine focuses on Chest Imaging. Drs. Lynch and Chung have assembled an expert panel of authors on the topics of:Approach to chest CT, CT screening for lung cancer,The solitary pulmonary nodule, Staging of lung cancer, Imaging of infections, ICU imaging, Pulmonary vascular diseases, Occupational and environmental lung disease, Idiopathic interstitial pneumonias, Connective tissue disease-related thoracic disease and more!

Colonoscopy is the bread and butter for endoscopists and advances in the procedure to reduce time, improve efficiency, and prevent errors are very important for this group. The newest advances look at colonoscopy efficiency and a better way to target tissue sampling, which avoids random biopsies and instead looks at ways to predict areas for sampling. The Guest Editors have selected top experts to provide these important updates and they also address current thinking that questions the continued value of colonoscopies as predictors of colon cancer. The issue will be a very popular one, and it needs to be heavily promoted.

Automatic detection and segmentation of anatomical structures in medical images are prerequisites to subsequent image measurements and disease quantification, and therefore have multiple clinical applications. This book presents an efficient object detection and segmentation framework, called Marginal Space Learning, which runs at a sub-second speed on a current desktop computer, faster than the state-of-the-art. Trained with a sufficient number of data sets, Marginal Space Learning is also robust under imaging artifacts, noise and anatomical variations. The book showcases 35 clinical applications of Marginal Space Learning and its extensions to detecting and segmenting various anatomical structures, such as the heart, liver, lymph nodes and prostate in major medical imaging modalities (CT, MRI, X-Ray and Ultrasound), demonstrating its efficiency and robustness.

Dr. Michael Pinsky has assembled an expert team of authors on the topic of Hemodynamic Monitoring. Articles topics include: The interface between monitoring and physiology at the bedside; Defining goals of resuscitation in the critically ill; Minimally invasive hemodynamic monitoring; Bedside ultrasound for the intensivist; Invasive hemodynamic monitoring; Functional hemodynamic monitoring; Using what you get: dynamic physiological signatures of critical illness; and Effect of organizational issues on resuscitation effectiveness.

This 6 volume set presents a groundbreaking resource in this branch of natural organic compounds and demonstrates how proton nuclear magnetic resonance (NMR) spectroscopy can be manipulated in structures of natural organic compounds. The authors provide the most comprehensive data of 17 kinds amounting to over 10,000 natural organic compounds. The 1st volume mainly illustrates the molecular formula and structures of alkaloids.

This issue of Cardiac Electrophysiology Clinics examines electrocardiography of complex arrhythmias. Topics include concealed conduction, right and left atrial macroreentrant tachycardias, focal atrial fachycardias, AV nodal and AV reentrant tachycardia, wide complex tachycardias, ventricular tachycardia in CAD, ECG characteristics of outflow tract VT, fascicular tachycardias, VT in non-ischemic dilated cardiomyopathy, VT originating from unusual sites, incessant VT and VT storms, ECG characteristics of TdP, VT in ARVC, and ventricular arrhythmia in inherited channelopathies, arrrhythmias in complex congenital heart disease, AV conduction disease and block, electrocardiographic analysis of paced rhythms.

Specific 3-D measurement techniques, based on optical or opto-electronic principles of image capture, can today provide a complete set of results to quantify, without any risk for the patient, the actual state of the rachis and the effects induced by the disease on the whole postural performance. The book deals with theoretical and clinical aspects of spinal deformities. It covers topics such as 3-D acquisition, reconstruction and modelling techniques; 3-D biomechanical analysis; 3-D etiological and prognostic aspects; 3-D treatment of scoliosis; surface topography and internal 3-D spinal and/or trunk anatomy.

Advanced techniques in image processing have led to many innovations supporting the medical field, especially in the area of disease diagnosis. Biomedical imaging is an essential part of early disease detection and often considered a first step in the proper management of medical pathological conditions. Classification and Clustering in Biomedical Signal Processing focuses on existing and proposed methods for medical imaging, signal processing, and analysis for the purposes of diagnosing and monitoring patient conditions. Featuring the most recent empirical research findings in the areas of signal processing for biomedical applications with an emphasis on classification and clustering techniques, this essential publication is designed for use by medical professionals, IT developers, and advanced-level graduate students.

The second edition of Rad Tech's Guide to MRI provides practicing and training technologists with a succinct overview of magnetic resonance imaging (MRI). Designed for quick reference and examination preparation, this pocket-size guide covers the fundamental principles of electromagnetism, MRI equipment, data acquisition and processing, image quality and artifacts, MR Angiography, Diffusion/Perfusion, and more. Written by an expert practitioner and educator, this handy reference guide: Provides essential MRI knowledge in a single portable, easy-to-read guide Covers instrumentation and MRI hardware components, including gradient and radio-frequency subsystems Provides techniques to handle flow imaging issues and improve the quality of MRIs Explains the essential physics underpinning MRI technology Rad Tech's Guide to MRI is a must-have resource for student radiographers, especially those preparing for the American Registry of Radiation Technologist (ARRT) exams, as well as practicing radiology technologists looking for a quick reference guide.

Guest edited by Christopher Comstock of Memorial Sloan-Kettering, this issue of Radiologic Clinics will provide all of the latest guidelines and techniques for breast imaging. Modalities include MRI, MR-CAD, digital tomosynthesis, and ultrasound.

Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. "Imaging of the Human Brain in Health and Disease" examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases.

Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease.

This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease.
A focused introduction to imaging healthy and diseased brainsFocuses on the primary neurotransmitter releaseIncludes sigma, acetylcholine, opioid, and dopamine receptorsPresents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

This detailed volume presents a number of chapters that will aid researchers in jumping the hurdle preventing the popularization of advanced intravital imaging technology usage, namely the complicated experimental protocols. Leading researchers undertaking imaging studies in the field of bone and immune systems have contributed the chapters that aim to guide readers through these complex methodologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Intravital Imaging of Dynamic Bone and Immune Systems: Methods and Protocols will serve as an idea guide for general readers in order to establish and perform these experiments by their own.

Cardiac Imaging: Case Review helps you effectively prepare for certification, recertification, and practice in cardiovascular imaging with case studies that test your knowledge of all essential topics. This updated medical reference book allows you to see how to make confident, final diagnoses through accurate pattern recognition, clinical correlation, and differential diagnosis. "I would recommend it to any radiologist or cardiologist with more than a passing interest in cardiovascular imaging". Reviewed by: Dr Edward Nicol, Royal Brompton Hospital on behalf of RAD Magazine, October 2014 Review cases organized by level of difficulty with multiple-choice questions and answers that mimic the new format of cardiovascular radiology certification and recertification exams. Easily access in-depth explanations of any aspect of cardiac imaging with handy page references to current works, including Dr. Stephen W. Miller's Cardiac Imaging, 2nd Edition. Stay current with the aid of updated cases covering cardiac radiology, CT, and CT angiography. Gain a better understanding of all the material necessary for the exam through multiple examples of each existing heart disease entity.

Edited by leaders of the field, Rathan Subramaniam from Johns Hopkins and Jorge Barrio from UCLA, this issue of PET Clinics focuses on the evolving role of novel imaging techniques in negenerative and movement disorders common in the aged population.

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.