Analysis of medical data using engineering tools is a rapidly growing area, both in research and in industry, yet few texts exist that address the problem from an interdisciplinary perspective. Epileptic Seizures and the EEG: Measurement, Models, Detection and Prediction brings together biology and engineering practices and identifies the aspects of the field that are most important to the analysis of epilepsy. Analysis of EEG records The book begins by summarizing the physiology and the fundamental ideas behind the measurement, analysis and modeling of the epileptic brain. It introduces the EEG as a measured signal and explains its use in the study of epilepsy. Next, it provides an explanation of the type of brain activity likely to register in EEG measurements, offering quantitative analysis of the populations of neurons that contribute to both scalp and cortical EEG and discussing the limitations and effects that choices made in the recording process have on the data. The book provides an overview of how these EEG records are and have been analyzed in the past, concentrating on the mathematics relevant to the problem of classification of EEG. The authors use these extracted features to differentiate between or classify inter-seizure, pre-seizure and seizure EEG. The challenge of seizure prediction The book focuses on the problem of seizure detection and surveys the physiologically based dynamic models of brain activity. Finally, the book addresses the fundamental question: can seizures be predicted? Through analysis of epileptic activity spanning from 3 hours to 25 years, it is proposed that seizures may be predictable, but the amount of data required is greater than previously thought. Based on the authors' extensive research, the book concludes by exploring a range of future possibilities in seizure prediction.

A host of imaging techniques are available to clinical cardiologists, including nuclear imaging, echocardiography, computerized tomography, and magnetic-resonance imaging. Chamber size, ventricular function, valvular function, coronary anatomy, and myocardial perfusion are among a wide array of cardiac characteristics that can all be assessed noninvasively. Cardiovascular Imaging systematically reviews each of these major techniques and provides clinical data from well-designed research studies. Following a brief overview of non-invasive cardiac imaging and the stress modalities used to detect coronary disease, case-based chapters are devoted to each of the various imaging techniques. The final chapter provides a glimpse of future possibilities, particularly with respect to molecular imaging. The text is illustrated throughout with amply-sized images. Demonstrating the values and limitations of the imaging techniques, the book enables practitioners to determine which test, in which patient population, and for which purpose would be the most appropriate to use.

The field of gastrointestinal motility disorders has been expanding in recent times largely due to advances in diagnostic modalities. This coupled with new evidence to support best practices has increased the interest among clinical gastroenterologists, researchers, teachers and trainees.New advancesin the field of evaluation of functional bowel diseases and motility disorders, such as high-resolution manometry, 24-h pH impedance monitoring, Bravo capsule pH-metry, barostat, balloon expulsion test, barium and MR defecography, biofeedback, hydrogen breath tests, motility capsule (smartpill) etc. have significantly expanded the scope and outcome of treating such these disorders. However, presently there is nocomprehensiveguidethat coversall aspects of evaluation of GI motility.This contributed volumewill havechapters written by a panel of experts from the global academia, including from India, Singapore, Japan, Taiwan, Thailand, Europe and USA, integrating the body of knowledge on evaluation methods with evidence of best practices for the management of motility disorders. A chapter on how to set-up a manometry laboratory provides key information for clinicians and researchers who are planning to start working in this area. With 20 chapters in the book supported with numerous tables, flow charts, schematic diagrams and images, professionals will find it an essential reading.

This text discusses the basic aspects of multislice CT angiography with chapters on technical principles, basic scan technique for peripheral vascular imaging with multislice CT, image reconstruction with multislice CT, radiation doses, and contrast agent administration. Clinical applications for each major vascular territory are covered in-depth, with clear descriptions of the examination technique for assessing the peripheral vasculature including the aorta to detect various vascular pathologies. The section on MR angiography provides a comprehensive overview of the current state of magnetic resonance (MR) vascular imaging. The basic principles and technical features of MR angiography are outlined, with chapters on fundamentals of MR angiography and commonly used pulse sequences and contrast dosing. Specific chapters focus on each particular vascular territory including the extracranial and intracranial circulation, the pulmonary circulation, the thoracic and the abdominal aorta, the renal, and mesenteric circulation and both the lower and the upper extremity circulation. Easy to follow clinical protocols for angiographic imaging for the different vascular regions are provided. The text also addresses imaging of the venous circulation using MR and CT angiography.

The ability to manipulate and analyze pictorial information to improve medical diagnosis, monitoring, and therapy via imaging is a valuable tool that every professional working in radiography, medical imaging, and medical physics should utilize. However, previous texts on the subject have only approached the subject from a programming or computer science viewpoint at a mathematically inaccessible level. Unlike these previous publications, A Practical Approach to Medical Imaging Processing provides hands-on instruction, using the freely available software program ImageJ, on all of the skills needed to perform filtering and image enhancement techniques used in structured image discrimination. In this unique text, the author focuses exclusively on image processing and treats medical images in a generic way to highlight the features that all digital images have in common. The book first introduces the main topics in image processing and as it progresses, you will discover relevant points of good practice. The author validates each technique with a corresponding case study, which originates from a published journal article. The case studies demonstrate how the concepts of image processing are applied to real-life situations, such as how to uncover information suffering from distortion and pixel-size limitations. The accompanying downloadable resources contain the Windows version of the ImageJ software, digital images, and documents to be used during the practical activities included in each chapter. With its highly functional workbook approach, A Practical Approach to Medical Image Processing allows you to build your skills in image manipulation and to enjoy the benefits of this valuable field without having to code or develop your own program.

This definitive book is the companion volume to Clark's Positioning in Radiography. It is focused on special imagining procedures and techniques and interventional procedures. Bringing together conventional contrast media studies, computed tomography, ultrasound, magnetic resonance imaging, radionuclide imaging including PET, SPECT CT and PET MRI and digital interventional procedures into one volume, it is the essential source of information for students of Radiography and Radiographer Assistant Trainees. The book reflects as to why procedures are carried out in terms of the indications for justification under IRMER 2000 procedures and any NICE or other medical referral guidelines such as the Map of Medicine.The book adopts an anatomical systemic approach, designed to be a clear and comprehensive reference text. Each chapter is highly illustrated and contains sections detailing anatomy, pathology considerations, procedure methodology and an evaluation of recommended imaging modalities. Both conventional and cross-sectional procedures are described, giving details for each procedure on indications/contraindication, position of patient, imaging modality, imaging procedure, contrast media and injection data, and imaging analysis. Important information is provided on the parameters which affect image production and quality for each of the modalities described in the book as well as considering the risk benefit, sensitivity and specificity of procedures.Whilst keeping many of the standard procedures and successful changes and additions to the first edition (Clark's Special Procedures in Diagnostic Imaging), this new edition includes a number of new innovations as well as reflecting the changes in approach to radiographic technique as a result of the variety of different x-ray equipment platforms accompanying the new digital imaging technology environment and advancements across the range of modern imaging modalities. The innovations include a section on recommended imaging pathways for different disease processes, the addition of a number of procedures not covered in the original edition i.e. defecating proctograms and herniograms and virtual coloscopy . This author team has a wide experience in publication and access to modern radiography imaging departments where technique and procedures are constantly changing many of which are reflected, making this book state of the art and reflecting the changing and advanced role of the radiographer.

Focusing on anatomy and procedural strategy for atrial fibrillation and ventricular tachycardia, this atlas uses pictures and schematic diagrams to show how to use intracardiac echo (ICE) to assess anatomy, guide ablation, and prevent complications during interventional procedures, pulmonary vein stenosis, and embolic events. The authors review the state of the art and background support in the use of ICE in interventional electrophysiology procedures and the anatomy of both the atrial and ventricular chambers. They discuss innovative indications in the EP laboratory, future technologies such as 3-D echocardiography, and the integration of ICE with other types of imaging technology.

Formulated by members of the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN), Functional Imaging in Nephro-urology is not a textbook on uronephrology or radionuclides in nephro-urology, or even a book on new techniques in imaging. What the editor and authors provide here is a unique opportunity to evaluate the strategic management techniques (both diagnosis and follow-up) of a number of uronephrological entities.
Demonstrating the experience of the authors in using various imaging modalities, and detailing the benefits and controversies which are associated with their clinical applications, this text presents management strategies based on the patient, the choice of modality, and cost implications.
Detailed, well-referenced and highly illustrated, this is an important book for radiologists, nephrologists and urologists working with children and adults, specialists in renal nuclear medicine, and pediatricians.

Intracardiac Echocardiography is the first echocardiographic textbook of its kind to specifically cover ICE. Discussing all aspects of intracardiac ultrasound, it allows readers to perfect ICE image acquisition and helps to guide interpretation of this information during interventional and electrophysiologic procedures.

Unique and informative, the text explores:

• introductory echo physics
• currently available intracardiac ultrasound systems
• basic image acquisition
• the role of ICE in both the interventional and electrophysiology laboratory, as well as in the diagnostic setting.

Featuring expert commentary by leaders in the field, the book also includes high quality echocardiographic images illustrating how ICE is used in a wide variety of procedures such as transseptal catheterization, PFO and ASD closure, atrial fibrillation ablation procedures, and many others.

Over recent years there has been a vast expansion in the variety of imaging techniques available, and developments in machine specifications continue apace. If radiologists and radiographers are to obtain optimal image quality while minimising exposure times, a good understanding of the fundamentals of the radiological science underpinning diagnostic imaging is essential. The second edition of this well-received textbook continues to cover all technical aspects of diagnostic radiology, and remains an ideal companion during examination preparation and beyond. The content includes a review of basic science aspects of imaging, followed by a detailed explanation of radiological sciences, conventional x-ray image formation and other imaging techniques. The enormous technical advances in computed tomography, including multislice acquisition and 3D image reconstruction, digital imaging in the form of image plate and direct radiography, magnetic resonance imaging, colour flow imaging in ultrasound and positron radiopharmaceuticals in nuclear medicine, are all considered here. A chapter devoted to computers in radiology considers advances in radiology information systems and computer applications in image storage and communication systems. The text concludes with a series of general topics relating to diagnostic imaging. The content has been revised and updated throughout to ensure it remains in line with the Fellowship of the Royal College of Radiologists (FRCR) examination, while European and American perspectives on technology, guidelines and regulations ensure international relevance.

Diagnostic Imaging will help medical students, junior doctors, residents and trainee radiologists understand the principles behind interpreting all forms of imaging. Providing a balanced account of all the imaging modalities available including plain film, ultrasound, computed tomography, magnetic resonance imaging, radionuclide imaging and interventional radiology it explains the techniques used and the indications for their use. Organised by body system, it covers all anatomical regions. In each region the authors discuss the most suitable imaging technique and provide guidelines for interpretation, illustrating clinical problems with normal and abnormal images. Diagnostic Imaging is extensively illustrated throughout, featuring high quality full-colour images and more than 600 photographs. The images are downloadable in PowerPoint format from the brand new companion website at www.wileydiagnosticimaging.com, which also has over 100 interactive MCQs, to aid learning and teaching. When you purchase the book you also receive access to the Wiley E-Text: Powered by VitalSource. This is an interactive digital version of the book, featuring downloadable text and images, highlighting and note-taking facilities, bookmarking, cross-referencing, in-text searching, and linking to references and abbreviations. Diagnostic Imaging is also available on CourseSmart, offering extra functionality as well as an immediate way to access the book. For more details, see www.coursesmart.com or The Anytime, Anywhere Textbook section.

Now in its fourth edition, this book presents a complete course in electrocardiography (ECG) for students and a reference for advanced trainees and technicians. The author's step-by-step approach lets readers focus only on needed information and proceed at their own pace. Brief and to the point, the text explains how an electrocardiograph works, how to draw a hexaxial system, plot vectors, produce a good ECG tracing, and how to draw a spatial vector. Advanced material is clearly marked, allowing students to work through the complete text with just enough theory to understand the facts and providing advanced trainees with a review and foundation for further study.

Digestive diseases have always been a major threat to global health. Despite the rapid advances in various diagnostic modalities, many a time the final verdict can be elusive and present a diagnostic challenge for the attending doctor. The book presents 50 real life cases to illustrate an evidence based approach for the diagnosis, investigation and management of gastrointestinal diseases commonly encountered in everyday practice, with a special focus on the interpretation of endoscopic and radiological images. This book provides a pragmatic approach for medical students, residents, specialist trainees and specialists alike who have an interest in gastroenterology. Other healthcare providers, such as general practitioners, nurses and dieticians, will also benefit from these case illustrations. The authors of this book are based at the Institute of Digestive Disease, Chinese University of Hong Kong. This institute has contributed to major breakthroughs that have improved the clinical management of digestive diseases including, but not limited to, the advent of endoscopic therapies and minimally invasive surgery, molecular diagnostic tools for cancers and inflammatory bowel disease, and the development of novel treatments for acid peptic disease and viral hepatitis.

Epilepsy is a prevalent and serious neurological disorder. This vital textbook addresses the role of neuroimaging as a unique tool to provide in vivo biomarkers aimed at furthering our understanding of causes and consequences of epilepsy in a day-to-day clinical context. Unique in its approach, this translational book presents a critical appraisal of advanced pre-clinical biomarkers that allows capturing epileptogenesis at molecular, cellular, and neuronal system levels. The book is divided into four sections. Part I includes a series of chapters focused on imaging of early disease stages. Part II discusses lesion detection and network analysis methods. Part III focuses on imaging methods used to predict response to antiepileptic drugs and surgery. Finally, Part IV presents imaging techniques used to evaluate disease consequence.

Pass the ARRT certification exam on your first try with this all-in-one review! Mosby's Comprehensive Review of Radiography: The Complete Study Guide & Career Planner, 8th Edition provides a complete, outline-style review of the major subject areas covered on the ARRT examination in radiography. Each review section is followed by a set of questions testing your knowledge of that subject area. Three mock ARRT exams are included in the book, and more than 1,400 online review questions may be randomly combined to generate a virtually limitless number of practice exams. From noted educator and speaker William J. Callaway, this study guide is also ideal for use in radiography courses and in beginning your career as a radiographer. More than 2,300 review questions are provided in the book and on the Evolve website, offering practice in a computer-based, multiple-choice format similar to the ARRT exam. Colorful, outline-style review covers the major subject areas covered on the ARRT exam, and helps you focus on the most important information. Formats for ARRT questions include exhibits, sorted list, multiselect, and combined response. Rationales for correct and incorrect answers are included in the appendix. Key Review Points are included in every chapter, highlighting the need-to-know content for exam and clinical success. Mock exams on the Evolve website let you answer more than 1,200 questions in study mode, with immediate feedback after each question - or in exam mode, with feedback only after you complete the entire test. Career planning advice includes examples of resumes and cover letters, interviewing tips, a look at what employers expect, online submission of applications, salary negotiation, career advancement, and continuing education requirements; in addition, customizable resumes may be downloaded from Evolve. Electronic flashcards are included on Evolve, to help you memorize formulas, key terms, and other key information. Online test scores are date-stamped and stored, making it easy to track your progress. NEW! Updated content is built to the most current ARRT exam content specifications, providing everything you need to prepare for and pass the exam. NEW! Coverage of digital imaging is updated to reflect the importance of this topic on the Registry exam.

A complete and practical guide, this text describes how to produce high-quality radiographic and ultrasound images. The first half of the book covers equipment, safety, and technique - all major responsibilities of the veterinary technician. The second half details radiographic positioning for small animals, large animals, and exotics. Reflecting the major role of ultrasonography in veterinary practice, the book concludes with an expanded chapter on diagnostic ultrasound. Practical, concise clinical format Written at the appropriate reading level for technicians Abundant illustrations emphasize basic radiographic and ultrasonographic principles, techniques, and equipment used in veterinary practice Concise and understandable discussion of physics and radiography Examples of common artifacts show how to avoid misinterpretation of imaging studies Excellent coverage of radiation safety Practical technique charts Excellent coverage of small- and large-animal positioning Exotics chapter featuring rodents (including ferrets), reptiles, and birds Ultrasound chapter that includes normal ultrasonographic findings, along with corresponding images Helpful hints given for obtaining quality images and avoiding common pitfalls reflect the authors' experiences at a busy teaching institution New cardiac ultrasound scanning techniques with 20 new ultrasound images New images of the latest x-ray equipment Updated pedagogical features, including outlines, key points, chapter objectives, and helpful hints for veterinary technicians

Imaging informatics is a complex and historically rapidly changing field, knowledge of which is central to the practice of all imaging specialists. This convenient pocket guide provides the foundations of knowledge in informatics, allowing radiographers in training and in practice, assistant practitioners and other allied health professionals to understand, use and develop more efficient ways of imaging that will in turn deliver improved patient care.

Computer vision and machine intelligence paradigms are prominent in the domain of medical image applications, including computer assisted diagnosis, image guided radiation therapy, landmark detection, imaging genomics, and brain connectomics. Medical image analysis and understanding are daunting tasks owing to the massive influx of multi-modal medical image data generated during routine clinal practice. Advanced computer vision and machine intelligence approaches have been employed in recent years in the field of image processing and computer vision. However, due to the unstructured nature of medical imaging data and the volume of data produced during routine clinical processes, the applicability of these meta-heuristic algorithms remains to be investigated. Advanced Machine Vision Paradigms for Medical Image Analysis presents an overview of how medical imaging data can be analyzed to provide better diagnosis and treatment of disease. Computer vision techniques can explore texture, shape, contour and prior knowledge along with contextual information, from image sequence and 3D/4D information which helps with better human understanding. Many powerful tools have been developed through image segmentation, machine learning, pattern classification, tracking, and reconstruction to surface much needed quantitative information not easily available through the analysis of trained human specialists. The aim of the book is for medical imaging professionals to acquire and interpret the data, and for computer vision professionals to learn how to provide enhanced medical information by using computer vision techniques. The ultimate objective is to benefit patients without adding to already high healthcare costs.

This book covers the main mathematical and numerical models in computational electrocardiology, ranging from microscopic membrane models of cardiac ionic channels to macroscopic bidomain, monodomain, eikonal models and cardiac source representations. These advanced multiscale and nonlinear models describe the cardiac bioelectrical activity from the cell level to the body surface and are employed in both the direct and inverse problems of electrocardiology. The book also covers advanced numerical techniques needed to efficiently carry out large-scale cardiac simulations, including time and space discretizations, decoupling and operator splitting techniques, parallel finite element solvers. These techniques are employed in 3D cardiac simulations illustrating the excitation mechanisms, the anisotropic effects on excitation and repolarization wavefronts, the morphology of electrograms in normal and pathological tissue and some reentry phenomena. The overall aim of the book is to present rigorously the mathematical and numerical foundations of computational electrocardiology, illustrating the current research developments in this fast-growing field lying at the intersection of mathematical physiology, bioengineering and computational biomedicine. This book is addressed to graduate student and researchers in the field of applied mathematics, scientific computing, bioengineering, electrophysiology and cardiology.

Covering the basics of X-rays, CT, PET, nuclear medicine, ultrasound, and MRI, this textbook provides senior undergraduate and beginning graduate students with a broad introduction to medical imaging. Over 130 end-of-chapter exercises are included, in addition to solved example problems, which enable students to master the theory as well as providing them with the tools needed to solve more difficult problems. The basic theory, instrumentation and state-of-the-art techniques and applications are covered, bringing students immediately up-to-date with recent developments, such as combined computed tomography/positron emission tomography, multi-slice CT, four-dimensional ultrasound, and parallel imaging MR technology. Clinical examples provide practical applications of physics and engineering knowledge to medicine. Finally, helpful references to specialised texts, recent review articles, and relevant scientific journals are provided at the end of each chapter, making this an ideal textbook for a one-semester course in medical imaging.

Computational Retinal Image Analysis: Tools, Applications and Perspectives gives an overview of contemporary retinal image analysis (RIA) in the context of healthcare informatics and artificial intelligence. Specifically, it provides a history of the field, the clinical motivation for RIA, technical foundations (image acquisition modalities, instruments), computational techniques for essential operations, lesion detection (e.g. optic disc in glaucoma, microaneurysms in diabetes) and validation, as well as insights into current investigations drawing from artificial intelligence and big data. This comprehensive reference is ideal for researchers and graduate students in retinal image analysis, computational ophthalmology, artificial intelligence, biomedical engineering, health informatics, and more.

Handbook of Medical Image Computing and Computer Assisted Intervention presents important advanced methods and state-of-the art research in medical image computing and computer assisted intervention, providing a comprehensive reference on current technical approaches and solutions, while also offering proven algorithms for a variety of essential medical imaging applications. This book is written primarily for university researchers, graduate students and professional practitioners (assuming an elementary level of linear algebra, probability and statistics, and signal processing) working on medical image computing and computer assisted intervention.

Addressing the basic concepts of radiological physics and radiation protection, together with a structured approach to image interpretation, Radiology at a Glance is the perfect guide for medical students, junior doctors and radiologists. Covering the radiology of plain films, fluoroscopy, CT, MRI, intervention, nuclear medicine, and mammography, this edition has been fully updated to reflect advances in the field and now contains new spreads on cardiac, breast and bowel imaging, as well as further information on interventional radiology. Radiology at a Glance: * Assumes no prior knowledge of radiology * Addresses both theory and clinical practice through theoretical and case-based chapters * Provides structured help in assessing which radiological procedures are most appropriate for specific clinical problems * Includes increased image clarity Supported by 'classic cases' chapters in each section, and presented in a clear and concise format, Radiology at a Glance is easily accessible whether on the ward or as a quick revision guide.

Imaging Neuroinflammation provides an overview of the molecular and cellular basis of inflammation and its effects on neuroanatomy, reviews state-of-the-art imaging tools available to measure neuroinflammation, and describes the application of those tools to both preclinical animal disease models and human disease.This book is an authoritative reference on imaging neuroinflammation, MRI, neuroinflammation, MR Spectroscopy of inflammation, Iron imaging in inflammation, and more.

Written by world authorities, this reference explores the utilization and advancement of state-of-the-art imaging modalities for the analysis of pulmonary function-providing an up-to-date and global perspective of imaging applications with detailed contributions from experts in Europe, North America, Japan, and Australia.