Fault-Tolerant Process Control focuses on the development of general, yet practical, methods for the design of advanced fault-tolerant control systems; these ensure an efficient fault detection and a timely response to enhance fault recovery, prevent faults from propagating or developing into total failures, and reduce the risk of safety hazards. To this end, methods are presented for the design of advanced fault-tolerant control systems for chemical processes which explicitly deal with actuator/controller failures and sensor faults and data losses. Specifically, the book puts forward: * A framework for detection, isolation and diagnosis of actuator and sensor faults for nonlinear systems; * Controller reconfiguration and safe-parking-based fault-handling methodologies; * Integrated-data- and model-based fault-detection and isolation and fault-tolerant control methods; * Methods for handling sensor faults and data losses; and * Methods for monitoring the performance of low-level PID loops. The methodologies proposed employ nonlinear systems analysis, Lyapunov techniques, optimization, statistical methods and hybrid systems theory and are predicated upon the idea of integrating fault-detection, local feedback control, and supervisory control. The applicability and performance of the methods are demonstrated through a number of chemical process examples. Fault-Tolerant Process Control is a valuable resource for academic researchers, industrial practitioners as well as graduate students pursuing research in this area.

The recently published book by the author, "Engineering Heat Transfer", already dealt with exact computation of heat exchangers and tube banks. In design c- putationthisisaccomplishedviacorrectivefactors;thelattermakesitpossibleto compute the actual mean temperature difference by starting from the logarithmic onerelativeto?uidsinparallel?oworcounter?ow. As far as veri?cation computation is concerned, corrective factors were int- ducedtocomputeacertaincharacteristicfactorcorrectly,asisfundamentalforthis typeofcomputation. Basedontheabove,theauthordecidedtoinvestigatefurther,re?ne,andwiden thistopic:theoutcomeofthisworkhasresultedinthishandbook. Newtypesofexchangerswereexamined;thecalculationwasre?nedtoproduce practicallyexactvaluesforthefactors. Thescopeoftheinvestigationwasincreased by widening the range of the starting factors. Furthermore, a greater number of valuestobeincludedinthetableswasconsidered. Finally,afewcharacteristicsof certainvaluesofthecorrectivefactorswerehighlighted. The?rstsectionisanintroduction;itsummarizesthefundamentalcriteriaofheat transferandproceedstoillustratethebehaviorof?uidsinbothparallelandcounter ?ow. Italsoshowshowtocomputethemeanisobaricspeci?cheatforsome? uids; itillustratesthesigni?canceofdesigncomputationandveri?cationcomputation. In addition,itillustrateshowtoproceedwithheatexchangersandtubebankstocarry outbothdesignandveri?cationcomputationcorrectly. AppendixAthenincludes36tablesasareferencefordesigncomputation,The tablescontainthecorrectivefactorsrequiredtoobtaintheactualmeantemperature differencebystartingfromthemeanlogarithmictemperaturedifferencerelativeto ?uidsinparallel?oworcounter?ow. Finally, Appendix B includes 35 tables for veri?cation computation. As far as heatexchangers areconcerned, itshowsthevaluesoffactor ? whichisrequired forthistypeofcomputation. Thevaluesofthecorrectivefactorsforcoilsandtube banksarealsopresented. Milano,Italy DonatelloAnnaratone v Notation c=speci?cheat(J/kgK) d=diameter(m) E=ef?ciencyfactor h=enthalpy(kJ/kg) k=thermalconductivity(W/mK) M=mass?owrate(kg/s) m=massmoisturepercentage(%) q=heatpertimeunit(W) 2 S=surface(m ) ? t=temperature( C) 2 U=overallheattransfercoef?cient(W/m K) x=thickness(m) 2 ? =heattransfercoef?cient(W/m K) ? =characteristicfactor ? =characteristicfactor ? =ef?ciency ? =correctivefactor ? =correctivefactor ? =characteristicfactor ? ?t =temperaturedifference( C) vii viii Notation Superscripts =heating?uid =heated?uid Subscripts c=counter?ow e=exchanger i=inside l=logarithmic m=mean o=outside p=constantpressure(isobaric),parallel?ow w=wall 1=inlet(forheatingorheated?uid) 2=outlet(forheatingorheated?uid) Contents 1 Introduction to Computation ...1 1. 1 GeneralConsiderations ...1 1. 2 MeanIsobaricSpeci?cHeat ...3 1. 2. 1 WaterandSuperheatedSteam ...4 1. 2. 2 AirandOtherGases...4 2 Design Computation...7 2. 1 Introduction ...7 2. 2 FluidsinParallelFloworinCounterFlow ...8 2. 3 TheMeanDifferenceinTemperatureinReality ...12 2. 3. 1 FluidsinCrossFlow...14 2. 3. 2 HeatExchangers...15 2. 3. 3 Coils...19 2. 3. 4 TubeBankswithVariousPassagesoftheExternalFluid . 21 3 Veri?cation Computation ...25 3. 1 Introduction ...25 3. 2 FluidsinParallelFloworinCounterFlow ...25 3. 3 Factor?inRealCases...33 3. 3. 1 FluidswithCrossFlow ...

This book represents a first considered attempt to study the factors that conditioned industrial chemistry for war in 1914-18. Taking a comparative perspective, it reflects on the experience of France, Germany, Austria, Russia, Britain, Italy and Russia, and points to significant similarities and differences. It looks at changing patterns in the organisation of industry, and at the emerging symbiosis between science, industry and the military.

Successful industrial heterogeneous catalysts fulfill several key require ments: in addition to high catalytic activity for the desired reaction, with high selectivity where appropriate, they also have an acceptable commercial life and are rugged enough for transportation and charging into plant reactors. Additional requirements include the need to come online smoothly in a short time and reproducible manufacturing procedures that involve convenient processes at acceptable cost. The development of heterogeneous catalysts that meet these (often mutually exclusive) demands is far from straightforward, and in addition much of the actual manufacturing tech nology is kept secret for commercial reasons-thus there is no modern text that deals with the whole of this important subject. Principles of Catalyst Development, which deals comprehensively with the design, development, and manufacture of practical heterogeneous catalysts, is therefore especially valuable in meeting the long-standing needs of both industrialists and academics. As one who has worked extensively on a variety of catalyst development problems in both industry and academia, James T. Richardson is well placed to write an authoritative book covering both the theory and the practice of catalyst development. Much of the material contained in this book had its origin in a series of widely acclaimed lectures, attended mainly by industrial researchers, given over many years in the United States and Europe. All those in industry who work with catalysts, both beginners and those of considerable experience, should find this volume an essential guide."

The purpose of this volume is to provide a brief review of the previous work on model reduction and identifi cation of distributed parameter systems (DPS), and develop new spatio-temporal models and their relevant identifi cation approaches. In this book, a systematic overview and classifi cation on the modeling of DPS is presented fi rst, which includes model reduction, parameter estimation and system identifi cation. Next, a class of block-oriented nonlinear systems in traditional lumped parameter systems (LPS) is extended to DPS, which results in the spatio-temporal Wiener and Hammerstein systems and their identifi cation methods. Then, the traditional Volterra model is extended to DPS, which results in the spatio-temporal Volterra model and its identification algorithm. All these methods are based on linear time/space separation. Sometimes, the nonlinear time/space separation can play a better role in modeling of very complex processes. Thus, a nonlinear time/space separation based neural modeling is also presented for a class of DPS with more complicated dynamics. Finally, all these modeling approaches are successfully applied to industrial thermal processes, including a catalytic rod, a packed-bed reactor and a snap curing oven. The work is presented giving a unifi ed view from time/space separation. The book also illustrates applications to thermal processes in the electronics packaging and chemical industry. This volume assumes a basic knowledge about distributed parameter systems, system modeling and identifi cation. It is intended for researchers, graduate students and engineers interested in distributed parameter systems, nonlinear systems, and process modeling and control.

Nanoparticles presents the remarkable variety of nanoparticle families, compositions, structures, and functions. The book discusses nanoparticles made of semiconductors, metals, metal-oxides, organics, biological and hybrid constituents. Through a wealth of examples and case studies, supplemented by numerous figures, readers that are not necessarily active or experts in this area acquire a broad overview of this exciting field at the interface between scientifi c research and practical technologies. The contents summarize the contributions to this field of diverse scientific and technological disciplines- chemistry, physics, biology, electronics and others providing acomprehensive knowledge- the types of nanoparticles, their compositions and how the relationships between the atomic constituents affect their properties, as well as potential applications of nanoparticles. - Covers diverse uses of nanoparticles in scientifi c research and industrial applications, underscoring their extraordinary diversity and potential utilization. - Experimental and conceptual approaches applied to the study of nanoparticles are discussed extensively. Additional references provide the reader with a basis for further study. - Also available by Professor Jelinek: Biomimetics - A Molecular Perspective (2013), ISBN: 978-3-11-028117-0

By drawing together the current theoretical and experimental understanding of the phenomena of delayed hydride cracking (DHC) in zirconium alloys, The Effect of Hydrogen and Hydrides on the Integrity of Zirconium Alloy Components: Delayed Hydride Cracking provides a detailed explanation focusing on the properties of hydrogen and hydrides in these alloys. Whilst the emphasis lies on zirconium alloys, the combination of both the empirical and mechanistic approaches creates a solid understanding that can also be applied to other hydride forming metals. This up-to-date reference focuses on documented research surrounding DHC, including current methodologies for design and assessment of the results of periodic in-service inspections of pressure tubes in nuclear reactors. Emphasis is placed on showing how our understanding of DHC is supported by progress in general understanding of such broad fields as the study of hysteresis associated with first order phase transformations, phase relationships in coherent crystalline metallic solids, the physics of point and line defects, diffusion of substitutional and interstitial atoms in crystalline solids, and continuum fracture and solid mechanics. Furthermore, an account of current methodologies is given illustrating how such understanding of hydrogen, hydrides and DHC in zirconium alloys underpins these methodologies for assessments of real life cases in the Canadian nuclear industry. The all-encompassing approach makes The Effect of Hydrogen and Hydrides on the Integrity of Zirconium Alloy Component: Delayed Hydride Cracking an ideal reference source for students, researchers and industry professionals alike.

Structure formation in crystallizing polymers, as occurring during processing, has not been treated so far in a coherent form. This fact explains, why this monograph is written as the ?rst book devoted to this subject. A quarter of a century ago the underdevelopment of this subject was obvious. Trial and error dominated. In fact, other apposite subjects as polymer melt rheology or heat transfer, had reached high levels. A great number of books has been devoted to them. Mold ?lling of amorphous polymers and the solidi?cation of these polymers by vitri?cation can nowadays be simulated numerically with a high degree of accuracy. In the solidi?ed sample even residual stresses and corresponding birefringence effects can accurately be 1 calculated . However, semicrystalline polymers, which form the majority of industrial po- mers, have been excluded from these considerations for good reasons. In fact, great uncertainties existed about the formation of quality determining crystalline str- tures. In particular, polyole?ns suffered from this shortcoming. In 1983 this fact instigated the polymer research group at the Johannes Kepler University in Linz to start with pertinent activities. The urgency of this kind of studies becomes evident, if advantages and hitches of these polymers are considered. 1. Versatility of processing: Injection molding into a great variety of shapes and sizes, from thin walled beakers to garden chairs, not to forget pipe and pro?le extrusion, cable coating, ?ber spinning, ?lm blowing. 2. Product qualities: Ductility, low density, good electric insulation, corrosion resistance, surface quality.

Methods of nuclear magnetic resonance (NMR) are increasingly applied in engineering sciences. The book summarizes research in the field of chemical and process engineering performed at the Karlsruhe Institute of Technology (KIT). Fundamentals of the methods are exposed for readers with an engineering background. Applications cover the fields of mechanical process engineering (filtration, solid-liquid separation, powder mixing, rheometry), chemical process engineering (trickle-bed reactor, ceramic sponges), bioprocess engineering (biofilm growth), and food process engineering (microwave heating, emulsions). Magnetic Resonance Imaging (MRI) as well as low-field NMR are covered with notes on hardware. Emphasis is placed on quantitative data analysis and image processing.

Stereoselective Synthesis of Tetrasubstituted Alkenes via Torquoselectivity-Controlled Olefination of Carbonyl Compounds with Ynolates, by Mitsuru Shindo and Kenji Matsumoto.- Stereoselective Synthesis of Z-Alkenes, by Woon-Yew Siau, Yao Zhang and Yu Zhao.- Stereoselective Synthesis of Mono-fluoroalkenes, by Shoji Hara.- Recent Advances in Stereoselective Synthesis of 1,3-Dienes, by Michael De Paolis, Isabelle Chataigner and Jacques Maddaluno.- Selective Olefination of Carbonyl Compounds via Metal-Catalyzed Carbene Transfer from Diazo Reagents, by Yang Hu and X. Peter Zhang.- Selective Alkene Metathesis in the Total Synthesis of Complex Natural Product, by Xiaoguang Lei and Houhua Li.- Olefination Reactions of Phosphorus-Stabilized Carbon Nucleophiles, by Yonghong Gu and Shi-Kai Tian.- Alkene Synthesis Through Transition Metal-Catalyzed Cross-Coupling of N-Tosylhydrazones, by Yan Zhang and Jianbo Wang.

This book is about two special topics in rheological fluid mechanics: the elasticity of liquids and asymptotic theories of constitutive models. The major emphasis of the book is on the mathematical and physical consequences of the elasticity of liquids; seventeen of twenty chapters are devoted to this. Constitutive models which are instantaneously elastic can lead to some hyperbolicity in the dynamics of flow, waves of vorticity into rest (known as shear waves), to shock waves of vorticity or velocity, to steady flows of transonic type or to short wave instabilities which lead to ill-posed problems. Other kinds of models, with small Newtonian viscosities, give rise to perturbed instantaneous elasticity, associated with smoothing of discontinuities as in gas dynamics. There is no doubt that liquids will respond like elastic solids to impulses which are very rapid compared to the time it takes for the molecular order associated with short range forces in the liquid, to relax. After this, all liquids look viscous with signals propagating by diffusion rather than by waves. For small molecules this time of relaxation is estimated as lQ-13 to 10-10 seconds depending on the fluids. Waves associated with such liquids move with speeds of 1 QS cm/s, or even faster. For engineering applications the instantaneous elasticity of these fluids is of little interest; the practical dynamics is governed by diffusion, .say, by the Navier-Stokes equations. On the other hand, there are other liquids which are known to have much longer times of relaxation."

Flow Control Methods and Devices in Micrometer Scale Channels, by Shuichi Shoji and Kentaro Kawai. Micromixing Within Microfluidic Devices, by Lorenzo Capretto, Wei Cheng, Martyn Hill and Xunli Zhang. Basic Technologies for Droplet Microfluidics, by Shaojiang Zeng, Xin Liu, Hua Xie and Bingcheng Lin. Electrorheological Fluid and Its Applications in Microfluidics, by Limu Wang, Xiuqing Gong and Weijia Wen. Biosensors in Microfluidic Chips, by Jongmin Noh, Hee Chan Kim and Taek Dong Chung. A Nanomembrane-Based Nucleic Acid Sensing Platform for Portable Diagnostics, by Satyajyoti Senapati, Sagnik Basuray, Zdenek Slouka, Li-Jing Cheng and Hsueh-Chia Chang. Optical Detection Systems on Microfluidic Chips, by Hongwei Gai, Yongjun Li and Edward S. Yeung. Integrated Microfluidic Systems for DNA Analysis, by Samuel K. Njoroge, Hui-Wen Chen, Ma gorzata A. Witek and Steven A. Soper. Integrated Multifunctional Microfluidics for Automated Proteome Analyses, by John K. Osiri, Hamed Shadpour, Ma gorzata A. Witek and Steven A. Soper. Cells in Microfluidics, by Chi Zhang and Danny van Noort. Microfluidic Platform for the Study of Caenorhabditis elegans, by Weiwei Shi, Hui Wen, Bingcheng Lin and Jianhua Qin."

Thermal Separation Technology is a key discipline for many industries and lays the engineering foundations for the sustainable and economic production of high-quality materials. This book provides fundamental knowledge on this field and may be used both in university teaching and in industrial research and development. Furthermore, it is intended to support professional engineers in their daily efforts to improve plant efficiency and reliability. Previous German editions of this book have gained widespread recognition. This first English edition will now make its content available to the international community of students and professionals. In the first chapters of the book the fundamentals of thermodynamics, heat and mass transfer, and multiphase flow are addressed. Further chapters examine in depth the different unit operations distillation and absorption, extraction, evaporation and condensation, crystallization, adsorption and chromatography, and drying, while the closing chapter provides valuable guidelines for a conceptual process development.

Polysiloxanes are the most studied inorganic and semi-inorganic polymers because of their many medical and commercial uses. The Si-O backbone endows polysiloxanes with intriguing properties: the strength of the Si-O bond imparts considerable thermal stability, and the nature of the bonding imparts low surface free energy. Prostheses, artificial organs, objects for facial reconstruction, vitreous substitutes in the eyes, and tubing take advantage of the stability and pliability of polysiloxanes. Artificial skin, contact lenses, and drug delivery systems utilize their high permeability. Such biomedical applications have led to biocompatability studies on the interactions of polysiloxanes with proteins, and there has been interest in modifying these materials to improve their suitability for general biomedical application. Polysiloxanes examines novel aspects of polysiloxane science and engineering, including properties, work in progress, and important unsolved problems. The volume, with ten comprehensive chapters, examines the history, preparatin and analysis, synthesis, characterization, and applications of these polymeric materials.

Kalia and Fu's novel monograph covers cryogenic treatment, properties and applications of cryo-treated polymer materials. Written by numerous international experts, the twelve chapters in this book offer the reader a comprehensive picture of the latest findings and developments, as well as an outlook on the field. Cryogenic technology has seen remarkable progress in the past few years and especially cryogenic properties of polymers are attracting attention through new breakthroughs in space, superconducting, magnetic and electronic techniques. This book is a valuable resource for researchers, educators, engineers and graduate students in the field and at technical institutions.

Today, ergot alkaloids have found widespread clinical use and more than 50 formulations contain natural or semisynthetic ergot alkaloids. They are used in the treatment of uterine atonia, postpartum bleeding, migraine, orthostatic circulatory disturbances, senile cerebral insufficiency, hypertension, hyp- prolactinemia, acromegaly, and Parkinsonism. Recently, new therapeutic - plications have emerged, e.g., against schizophrenia and for therapeutic usage based on newly discovered antibacterial and cytostatic effects, immunomodu- tory and hypolipemic activity.The broad physiological effects of ergot alkaloids are based mostly on their interactions with neurotransmitter receptors on the cells. The presence of "hidden structures'' resembling some important neu- humoral mediators (e.g., noradrenaline, serotonin, dopamine) in the molecules of ergot alkaloids could explain their interactions with these receptors 1]. Ergot alkaloids are produced by the filamentous fungi of the genus, Claviceps (e.g., Claviceps purpurea - Ergot, Mutterkorn). On the industrial scale these alkaloids were produced mostly by parasitic cultivation (field production of the ergot) till the end of the 1970s. Today this uneconomic method has been - placed by submerged fermentation. Even after a century of research on ergot alkaloids the search still continues for new, more potent and more selective ergot alkaloid derivatives.

This volume includes 20 contributions of the 12th meeting on Analytical Ultracentrifugation from March 1-2, 2001 in Duisburg, Germany. Various fields of ultracentrifugation are covered concerning research problems in biochemistry, biophysical chemistry and macromolecular chemistry as well as interacting systems. New investigations concerning the sedimentation theory are presented. The phase transition of gels is dealt with, as is the sedimentation-diffusion equilibrium of gels. One section contains the hydrodynamics of biopolymers.

This is the second volume of Multiphase Science and TechnoJogy, a new international series of books intended to provide authoritative overviews of im portant areas in multiphase systems. The alm is to have systematic and tutorial presentations of the state of knowledge in various areas. The objective of the chapters is to allow the nonspecialist reader to gain an up-to-date idea of the present state of development in a given subject. The response to Volume 1 of the se ries has been very positive, and we believe that the present volume will be equally weil received. Volume 1 was concerned entirely with gas-liquid systems, and the first four chapters of the present volume also relate to such systems. However, the inten tion of the se ries is to cover a wide range of multiphase systems, and we are, therefore, pleased to include in the present volume chapters that refer to liquid liquid and gas-solid multiphase flows, respectively. The first chapter in the present volume is by Professor A. E. Dukler of the University of Houston, Texas, and Professor Y. Taitel of Tel-Aviv University, Israel."

"Batch Chemical Process Integration: Analysis, Synthesis and Optimization" is an excellent source of information on state-of-the-art mathematical and graphical techniques for analysis, synthesis and optimization of batch chemical plants. It covers recent techniques in batch process integration with a particular focus on the capabilities of the mathematical techniques. There is a section on graphical techniques as well as performance comparison between graphical and mathematical techniques. Prior to delving into the intricacies of wastewater minimisation and heat integration in batch processes, the book introduces the reader to the basics of scheduling which is aimed at capturing the essence of time. A chapter on the synthesis of batch plants to highlight the importance of time in design of batch plants is also presented through a real-life case study. The book is targeted at undergraduates and postgraduate students, researchers in batch process integration, practising engineers and technical managers.

Organometallic chemistry is a well established research area at the interface of organic and inorganic chemistry. In recent years this field has undergone a ren aissance as our understanding of organometallic structure, properties and mechanism has opened the way for the design of organometallic compounds and reactions tailored to the needs of such diverse areas as medicine, biology, materials and polymer sciences and organic synthesis. For example, in the de velopment of new catalytic processes, organometallic chemistry is helping meet the challenge to society that the economic and environmental necessities of the future pose. As this field becomes increasingly interdisciplinary, we recognize the need for critical overviews of new developments that are of broad significance. This is our goal in starting this new series Topics in Organometallic Chemistry. The scope of coverage includes a broad range of topics of pure and applied or ganometallic chemistry, where new breakthroughs are being achieved that are of significance to a larger scientific audience. Topics in Organometallic Chemistry differs from existing review series in that each volume is thematic, giving an overview of an area that has reached a stage of maturity such that coverage in a single review article is no longer possible. Furthermore, the treatment addresses a broad audience of researchers, who are not specialists in the field, starting at the graduate student level. Discussion of possible future research directions in the areas covered by the individual volumes is welcome."

Proceedings of the NATO Advanced Study Institute on Polymer Colloids, Strasbourg, France, July 3-15, 1988