Physician Assistant Clinics aims to provide an authoritative and continuously updated clinical information resource that covers all of the relevant PA specialties. Our clinical review articles address the key points, diagnosis, prognosis, clinical management, and complications of disease and techniques, evidence, and controversies in the field. Information for quick reference, as well as in-depth coverage of a topic, is a hallmark of the Clinics' series. This issue of Physician assistant Clinics, guest edited by Kim Zuber, PA-C and Jane S. Davis, DNP, CRNP, brings together expert PAs, NPs, and MDs to give PAs deep insights into the latest advancements in renal disease and show how they are applicable in practice. Articles in this issue include: Will the Real Kidney Patient Please Stand Up?; Introduction of the Kidney Patient; The Surgical Kidney Patient; CardioRenal: The Pump and the Filter; Dosing the Kidney Patient; ABCs of the ICU; Pediatrics: Forgotten Stepchild of Nephrology; Acute Kidney Injury (AKI); Outpatient Management of the CKD Patient; Nephrolithiasis: The Rolling Stones; Transplant and the New Protocols; Health Disparities in Kidney Disease; and Diet and the Kidney.

Since the 4th Series of this Fascicle was published, there have been considerable advances in our understanding of tumors within the serosal membranes, in particular the classification of mesothelial tumors and their genetics. This 5th Series Fascicle aligns with the terminology recommended by the WHO in its most recent edition for pleural and pericardial tumors, with expansion to reflect serosal membranes at other sites and including recognition of mesothelioma in situ.

Clinical Chemistry focuses on the laboratory diagnosis of the most common diseases by organ system and relates diagnostic testing to the pathophysiology of the diseases in development of the differential diagnosis. Essential analytical methodology for interpreting test results is fully integrated into discussions. The second edition includes additional material such as newer cardiac biomarkers soluble ST2, galexin-3, CD 146; hepatitis testing (A, B, C, D, E); use of high-resolution serum protein electrophoresis; procalcitonin; tumor markers such as neuron-specific enolase and KRAS mutation; estimated glycated hemoglobin and glucose "time in range" for monitoring glucose control; identification of specific islet-cell antibodies in type 1 diabetes mellitus; discussion of all types of diabetes mellitus; and more drugs for therapeutic monitoring (lithium, methotrexate). Current reference intervals and nomenclature have been used throughout, and additional summary tables have been added where appropriate. New clinical cases are included in every chapter.

Selected as a Doody's Core Title for 2022! Fully revised and up- to- date, Ioachim's Lymph Node Pathology, 5th Edition, offers valuable guidance in the diagnostic interpretation of lymph node biopsies. Continuing the tradition of excellence established by Dr. Harry L. Ioachim, Dr. L. Jeffrey Medeiros of The University of Texas MD Anderson Cancer Center offers a comprehensive, clinically useful approach to all the various nonmalignant lesions, lymphomas, other neoplasms, and metastatic tumors in lymph nodes. Discussion of each pathologic entity includes definition, clinical syndrome, histopathology, immunopathology, molecular genetic findings, and differential diagnosis. In addition, chapters have a useful checklist for each entity. "Brings together the background information, the morphologic descriptions, the recommended procedures, the supportive illustrations, and the interpretation of results necessary to make the correct diagnosis." (from the Preface to the fourth edition) Features expanded information on the methods of flow cytometry, immunohistochemistry, and molecular diagnosis. Contains more than 700 high-quality illustrations, including over 600 in full color. Includes sections on normal lymph node; diagnostic methods; lymphadenitides; lymphadenopathies; lymphomas; lymphoproliferative disorders associated with immune deficiencies; dendritic cell, histiocytic and granulocytic/monocytic neoplasms; spindle cell neoplasms of lymph nodes; vascular neoplasms of lymph nodes; and metastatic tumors in lymph nodes. Incorporates guidelines of the revised fourth edition of the World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,

Neuropathology of Drug Addictions and Substance Misuse, Volume 3: General Processes and Mechanisms, Prescription Medications, Caffeine and Areca, Polydrug Misuse, Emerging Addictions and Non-Drug Addictions is the third of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 3 addresses prescription medications, caffeine, polydrug misuse, and non-drug addictions. Each section provides data on the general, molecular, cellular, structural, and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad of material and substances.

For 40 years, Bancroft's Theory and Practice of Histological Techniques has established itself as the standard reference for histotechnologists and laboratory scientists, as well as histopathologists. With coverage of the full range of histological techniques used in medical laboratories and pathology departments, it provides a strong foundation in all aspects of histological technology - from basic methods of section preparation and staining, to advanced diagnostic techniques such as immunocytochemistry and molecular testing. This revised and updated 8th Edition by Kim S. Suvarna, Christopher Layton, and John D. Bancroft is a one-stop reference for all those involved with histological preparations and applications, from student to highly advanced laboratory professional. Presents a thorough, up-to-date, and detailed approach to the theory and protocols for preparing cells and tissues for laboratory evaluation, covering topics ranging from basic to advanced Features new content on automation (computer logging and tracking, sub-sampling and archiving of samples), digital scanning techniques for slides used in remote/telepathology, and specialist molecular techniques. Provides superb visual guidance through the use of vivid color illustrations, including additional illustrations of diagnostic modalities and techniques. Contains more summary tables, charts, and boxes throughout for quick reference. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Constituting a large percentage of everyday diagnostic practice, melanocytic pathology is a complex and challenging area with many difficult-to-diagnose lesions. This highly illustrated reference, written by three of the world's leading dermatopathologists, provides authoritative guidance in the accurate diagnosis of even the most challenging pigmented skin tumors, helping you avoid pitfalls and recognize mimics. Covers nearly every variant of melanocytic tumors you're likely to see. Emphasizes how to arrive at an efficient, accurate diagnosis, and includes dermoscopic findings for optimal diagnostic precision. Discusses modern analytic techniques (cytogenetics, molecular studies) and how to use them for diagnosis. Includes numerous case examples to illustrate the differential diagnoses and work-up; how to use ancillary techniques, along with their pros, cons, and limitations; and clinical follow-up. Presents the knowledge and experience of Klaus Busam, Pedram Gerami, and Richard Scolyer, - three dermatopathologists who are globally renowned for their expertise in melanoma pathology and analysis of melanocytic tumors by modern ancillary diagnostic techniques. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Early identification and diagnosis by type and stage is the key to high survival rates with thyroid cancer. To present the pathologist with current clinical information on diagnosis, differential diagnosis, staging, and prognosis of thyroid cancers, topics presented are: Poorly differentiated thyroid carcinoma; Paraganglimoa; Immunohistochemical markers for evaluation and prognosis in thyroid carcinoma; Familial endocrine syndromes; Parathyroid enoplasia; Inflammatory lesions of the thyroid associated with cancer; Assessing biological aggression in adrenal cortical neoplasia; Pituitary neoplasia; and Pancreatic endocrine neoplasia. Peter Sadow, whose clinical practice and research involve studying the mechanisms of endocrine carcinogenesis through translational studies involving the proteomics and genomics of endocrine neoplasms, primarily of the thyroid and adrenal glands, leads this issue.

Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants and International Aspects is the second of three volumes in this informative series and offers a comprehensive examination of the adverse consequences of the most common drugs of abuse. Each volume serves to update the reader's knowledge on the broader field of addiction as well as to deepen understanding of specific addictive substances. Volume 2 addresses stimulants, club and dissociative drugs, hallucinogens, and inhalants and solvents. Each section provides data on the general, molecular and cellular, and structural and functional neurological aspects of a given substance, with a focus on the adverse consequences of addictions. Research shows that the neuropathological features of one addiction are often applicable to those of others, and understanding these commonalties provides a platform for studying specific addictions in more depth and may ultimately lead researchers toward new modes of understanding, causation, prevention, and treatment. However, marshalling data on the complex relationships between addictions is difficult due to the myriad material and substances.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome- and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout. Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other alterations; and details on personalized medicine targeted to specific genes Features more than 2,200 images throughout, including clinical and radiological images, algorithms, graphics, gross pathology, histology, and a wide range of special and immunohistochemical stains-all carefully annotated to highlight the most diagnostically significant factors Features time-saving bulleted text, key facts in each chapter, an extensive index, and numerous tables for quick reference and thorough understanding Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

In 1910, Karl Jaspers wrote a seminal essay on morbid jealousy in which he laid the foundation for the psychopathological phenomenology that through his work and the work of Hans Gruhle and Kurt Schneider, among others, would become the hallmark of the Heidelberg school of psychiatry. In "General Psychopathology," his most important contribution to the Heidelberg school, Jaspers critiques the scientific aspirations of psychotherapy, arguing that in the realm of the human, the explanation of behavior through the observation of regularity and patterns in it ( "Erklarende Psychologie") must be supplemented by an understanding of the "meaning-relations" experienced by human beings ( "Verstehende Psychologie").

Fanconi Anemia (FA), a rare genetic disease featuring excess cancer risk and chromosomal instability, has received growing interest after the discovery that one of the defective genes in FA is associated with high-impact diseases such as familial breast cancer and ovary cancers. A well-documented relationship has accumulated in several decades and up to recently, studies have linked FA with a redox imbalance (oxidative stress, OS) in FA cells. The toxicity mechanisms of crosslinking agents (mitomycin C and diepoxybutane) in FA cells, along with the roles of OS-related aldehydes and glutathione in FA and in other diseases, are critically discussed. Also discussed is the proinflammatory state in FA phenotype. Additionally, recent studies have discovered an impairment in the structure and function of mitochondria in FA cell lines, while mitochondrial dysfunction in FA patients has so far been an unexplored field warranting ad hoc investigations. This book provides the readers with up-to-date information and perspectives on Fanconi anemia and oxidative stress that may prompt further elucidation of this intriguing disease, along with working hypotheses in clinical research and patients' management.

Comprehensive and practical, Mills and Sternberg's Diagnostic Surgical Pathology, 7th Edition, presents advanced diagnostic techniques for differential diagnosis of the surgical specimen and the latest information on all currently known diseases. Led by Drs. Teri A. Longacre, Joel K. Greenson, Jason, L. Hornick, and Victor E. Reuter, a virtual "who's who" of experts in the field provide authoritative guidance on the diagnostic evaluation of every type of specimen from every anatomic site. Visually stunning and thoroughly up to date, this classic two-volume reference is a must-have resource no matter what your level of training or expertise. Covers virtually all diseases seen by surgical pathologists, grouped anatomically and focused on differential diagnosis for each type of specimen. Emphasizes practical, real-world guidance that mimics a personal consultation with expert colleagues, offering the authors' personal approaches to biopsy evaluation throughout. Includes significant updates in key areas of the field, particularly in immunohistochemistry and molecular pathology. Features more than 4,500 full-color illustrations, each color-balanced to dramatically improve image quality. Incorporates updated World Health Organization (WHO) terminology regarding tumor diagnosis. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,

Knowledge of cutaneous lymphomas has been growing significantly as a result of important discoveries in immunology, molecular biology, and immunohistochemistry. Improved clinical pathologic correlation and follow-up data, as well as the synergistic collaboration among different lymphoma registries and specialists from several academic medical centers have greatly contributed to the understanding of the difficult field of cutaneous lymphoproliferative disorders. While these advances have increased understanding of skin lymphomas, they have also produced an extensive and sometimes confusing litany of articles, studies, and classification schemes. This issue on Cutaneous Lymphomas in Surgical Pathology Clinics provides an organized and updated review of this challenging topic by leading experts. It bridges critical knowledge gaps in the diagnosis of cutaneous lymphomas. Sezary Syndrome, Mycosis Fungoides and variants are presented along with B-cell, CD30, lymphoproliferative disorders among others. In addition to multiple clinical and microscopic images, tables and algorithms are presented to aid in diagnosis and staging. Beyond its usefulness to general pathologists, dermatopathologists, and hematopathologists, this information is intended to be helpful for dermatologists, hematologists/oncologists, fellows, and residents.

Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility.

This book aims to examine all immunohistochemical and molecular pathological biomarkers that can be useful and effective in patient diagnosis, prognosis and treatment decision, especially when faced with a carcinoma of unknown primary. For this purpose, epithelial malignancies of all systems and related biomarkers are examined one by one, and to look at the subject through the metastatic regions window, biomarkers that can be used to determine the primary focus for carcinomas seen in the areas most frequently metastasized are emphasized. With this bi-directional perspective, the reader is able to find biomarkers of any type of carcinoma on a system basis, as well as access to which biomarkers can be used when faced with a metastatic carcinoma. The importance of biomarkers in patient follow-up and treatment is also conveyed through the clinician's eye, and so biomarkers are handled with a holistic approach in all aspects. This book primarily targets pathologists, as well as clinicians (oncologists and surgeons) who manage cancer patients.

Head and neck pathology is increasingly becoming an attractive field for the new generations of pathologists, fully aware that in the era of specialization the information contained in the treatise of general surgical pathology, although extremely valuable to create the basis of their knowledge, does not provide in its full picture the specific knowledge required to meet current diagnostic and prognostic requirements. The book Pathology of the Head and Neck presents in a single volume the most pertinent and updated information needed by the interested readers. Its contents have been divided into ten chapters. The first one covers the spectrum of precursor and neoplastic lesions of the squamous epithelium. It is followed by chapters devoted to nasal cavities and paranasal sinuses, oral cavity, maxillofacial skeleton and teeth, salivary glands, nasopharynx and Waldeyers ring, larynx and hypopharynx, ear and temporal bone, neck and neck dissection, as well as eye and ocular adnexa. The authors of the different chapters have been selected among internationally recognized experts, all of them members of the Working Group on Head and Neck Pathology of the European Society of Pathology.

Surgical pathologists play a central role in patient surveillance and treatment by surgeons, radiation oncologists, and medical oncologists. Although salivary gland tumors are uncommon overall, their histopathologic diversity and challenge command the attention of practicing surgical pathologists. Atlas of Salivary Gland Pathology focuses on the diagnostic approach to salivary gland neoplasia-one of the more challenging fields within surgical pathology-emphasizing the need to understand downstream implications with respect to patient surveillance and treatment. The presence of formidable histologic mimicry in salivary gland neoplasia is well-documented in the pathology literature and has also been observed in the consultation practice of the volume editor. This textbook is designed with the needs of practicing surgical pathologists and pathologists-in-training in mind, providing a comprehensive overview of both common and rare salivary gland neoplasms. The primary educational objectives for readers include the following: 1) distinguish benign from low-grade malignant salivary gland neoplasms, 2) effectively use histochemical, immunohistochemical, and cytogenetic studies in challenging cases, 3) understand which diagnoses merit additional surgery and/or adjuvant therapy (radiation, chemotherapy), and 4) enhance pathologist-to-clinician communication in the setting of salivary gland disease.

This issue of Clinics in Laboratory Medicine on the topic of Laboratory Medicine in India will be Guest Edited by Tester F. Ashavaid, PhD, FACB, CSCi, and include the following article topics: Tuberculosis; Malaria; STIs and Dengue; Visceral Leishmaniasis; Neglected Tropical Diseases; Hepatitis; HIV; Diabetes; Cardiovascular diseases; Stroke; HPV / Cervical screening; Multiple congenital anomalies; Down Syndrome/Thalessemia; Muscle dystrophy; Spinal muscular atrophy; Wilson Disease; Hemophilia; National and International Accreditation; Blood Banking regulations; Distant Testing; Clinical Trials; Medical Tourism; International Reference labs; and Diagnostics in diet.

"In Situ Molecular Pathology and Co-Expression Analyses" explains, in easy-to-understand language, simplified waysof understanding and performing in situ hybridization and immunohistochemistry tests. The book also focuses on straightforward protocols used to simultaneously detect two or more proteins/nucleic acids within intact tissue by doing co-expression analyses.

The fields of in situ hybridization and immunohistochemistry have expanded rapidly due to the use of computer-based analysis. To get the most out of these automated platforms, researchers and diagnostic biomedical investigators must have a solid understanding of the basics of in situ-based tests, protocols, and regimens for troubleshooting.

Practicing molecular pathologists, clinical chemists, and toxicologists, as well as clinicians and researchers in training, will benefit from this book's clear presentation of protocols and theoretical framework.
Includes over 200 easy-to-follow experimental protocolsFeatures chapter-ending summaries of "Key Points to Remember" to bring beginners up to speed with any seasoned veteran in the fieldOffers two chapters written by industry leaders in the fields of in situ hybridization, immunohistochemistry, and computer software for co-expression analyses"

Brain, Part 1 of The Netter Collection of Medical Illustrations: Nervous System, 2nd Edition, provides a highly visual guide to this complex organ, from basic neurodevelopment, neuroanatomy, neurophysiology, and cognition to classic disorders including to epilepsy, hypothalamus/pituitary with disorders of consciousness and sleep, movement disorders, cerebellum, stroke, multiple sclerosis, neurologic infections, neuro-oncology, headaches, and brain trauma. This spectacularly illustrated volume in the masterwork known as the (CIBA) Netter "Green Books" has been expanded and revised by Drs. H. Royden Jones, Jr., Ted M. Burns, Michael J. Aminoff, and Scott L. Pomeroy to mirror the many exciting advances in medicine and imaging - offering unparalleled insights into the broad clinical spectrum of brain disorders. Get complete, integrated visual guidance on the brain with thorough, richly illustrated coverage. Quickly understand complex topics thanks to a concise text-atlas format that provides a context bridge between primary and specialized medicine. Clearly visualize how core concepts of anatomy, physiology, and other basic sciences correlate across disciplines. Benefit from matchless Netter illustrations that offer precision, clarity, detail and realism as they provide a visual approach to the clinical presentation and care of the patient. Gain a rich clinical view of all aspects of the brain in one comprehensive volume, conveyed through beautiful illustrations as well as up-to-date radiologic images. Clearly see the connection between basic science and clinical practice with an integrated overview of normal structure and function as it relates to pathologic conditions. Grasp current clinical concepts regarding development, pediatrics, and adult medicine captured in classic Netter illustrations, as well as new illustrations created specifically for this volume by artist-physician Carlos Machado, MD, and others working in the Netter style.

This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations.

This book provides up-to-date and practical knowledge in all aspects of whole slide imaging (WSI) by experts in the field. This includes a historical perspective on the evolution of this technology, technical aspects of making a great whole slide image, the various applications of whole slide imaging and future applications using WSI for computer-aided diagnosis The goal is to provide practical knowledge and address knowledge gaps in this emerging field. This book is unique because it addresses an emerging area in pathology for which currently there is only limited information about the practical aspects of deploying this technology. For example, there are no established selection criteria for choosing new scanners and a knowledge base with the key information. The authors of the various chapters have years of real-world experience in selecting and implementing WSI solutions in various aspects of pathology practice. This text also discusses practical tips and pearls to address the selection of a WSI vendor, technology details, implementing this technology and provide an overview of its everyday uses in all areas of pathology. Chapters include important information on how to integrate digital slides with laboratory information system and how to streamline the "digital workflow" with the intent of saving time, saving money, reducing errors, improving efficiency and accuracy, and ultimately benefiting patient outcomes. Whole Slide Imaging: Current Applications and Future Directions is designed to present a comprehensive and state-of the-art approach to WSI within the broad area of digital pathology. It aims to give the readers a look at WSI with a deeper lens and also envision the future of pathology imaging as it pertains to WSI and associated digital innovations.

Part of the comprehensive Biopsy Interpretation Series, the second edition of Biopsy Interpretation of the Uterine Cervix and Corpus provides an easy-to-follow, practical approach to normal histology, non-neoplastic conditions, and neoplasia of the cervix and uterine body. Focusing on the most common biopsies, this up-to-date bench reference emphasizes morphologic features and immunohistochemistry in the diagnostic material, with close attention paid to differential diagnosis, including benign mimics of tumors.Key Features Stay up to date with what's new in gynecologic pathology with an all-new chapter on metastatic tumors, plus updated references and terminology throughout. Focus on differential diagnosis and frequently encountered pitfalls of the most common entities observed in the cervix, endometrium, and myometrium. Clearly visualize the specimens you're likely to see with hundreds of high-quality images, both in the text and online. Get up-to-date guidance on ancillary tests such as in situ hybridization for HPV and molecular studies for microsatellite instability assessment and molar pregnancy. Test your knowledge online with over 50 questions ideal for self-assessment. Now with the print edition, enjoy the bundled interactive eBook edition, offering tablet, smartphone, or online access to: 50 questions for review and self-assessment, plus over 1,000 additional full-color images available only online. Complete content with enhanced navigation Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web Cross-linked pages, references, and more for easy navigation Highlighting tool for easier reference of key content throughout the text Ability to take and share notes with friends and colleagues Quick reference tabbing to save your favorite content for future use

Immunometabolism has emerged as an intersectional crossroad between metabolism and immune response. Over the past decade, it has become clear that most - if not all - immune cell functions are not separated from cellular metabolism. Although seminal works have addressed the metabolic fate of immune cells during differentiation and function, the physiological status of a given tissue is also dependent on the cell metabolism. The dialogue between immune cells and their microenvironment can also modulate cellular metabolism, which can trigger the onset and progression of a multitude of inflammation-mediated diseases. Thus, uncovering the specific characteristics of the metabolism in different immune cells types and in different conditions, can shed light into the molecular mechanisms of disease and help develop new drugs and therapeutic strategies to treat immune diseases. The edited volume Essentials aspects of Immunometabolism will give the readers a broad view on how metabolic pathways can influence many types of immune cells during activation, differentiation and function, in health and disease. Of note, the structure of the book was created thinking not only on the experienced immunologist but also on undergraduate and graduate students, physicians, and all members of the scientific community interested in this exciting field of research.