Die Standardlehrbucher zur Immunologie bieten meist sehr komplexe und detaillierte Informationen, die beim Leser bestimmte Kenntnisse uber Biochemie, Physiologie und Mikrobiologie voraussetzen. Dieses Kompendium wurde fur den "Erstkontakt" mit dieser komplexen Thematik konzipiert. Wichtige Basisinformationen uber die Struktur und Funktion von Zellen des Immunsystems, uber Antikorper, Zytokine und andere regulatorischen Molekule, sowie uber Abwehrmechanismen gegen Infektionserreger und spontan entstehende Tumore werden ebenso beschrieben wie unspezifische und spezifische Immunantworten und Storungen des Immunsystems durch Autoimmerkrankungen oder Allergien. Aufgrund der didaktischen Aufbereitung und den zahlreichen anschaulichen Abbildungen ist dieses Werk bestens als Nachschlagewerk und Lehrbuch fur Studenten der Medizin und Naturwissenschaften geeignet."

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Die Zytologie von Lunge und Pleura ist eine morphologisch vielfaltige und anspruchsvolle Untersuchungsmethode, die nur durch die Zusammenarbeit zwischen Klinikern, Radiologen, Labormedizinern und Zytologen eine prazise Diagnostik ermoeglicht. Dieses Buch ermoeglicht einen schnellen und detaillierten Zugang zur Information uber Lungen- und Pleuraerkrankungen. Der Materialgewinnung, mit Schwerpunkt endoskopischer Untersuchungsmethoden, und der Materialverarbeitung, inklusive Immunzytochemie und Flowzytometrie, sind eigene Kapitel gewidmet. Anschliessend werden benigne und maligne Erkrankungen mit Definition, Epidemiologie/AEtiologie sowie Klinik und Zytologie ausfuhrlich beschrieben. Zytologische Charakteristika sind fur eine schnelle Information durch die Hervorhebung in Bloecken gut ersichtlich und im Bildteil mit uber 200 farbigen Abbildungen belegt. Die Klinische Zytologie der Lunge und Pleura ist fur den in Ausbildung stehenden Zytologen ein Lehrbuch und fur den klinisch Tatigen ein ubersichtliches Nachschlagewerk fur die tagliche Praxis. Fur alle Kliniker ist dieses Buch ein nutzlicher Ratgeber in diagnostischen Fragestellungen der Pulmologie.

Gain critical insight into the structure-function relationships and the pathological basis of human disease with Netter's Illustrated Human Pathology. With a visually vibrant approach, this atlas provides clear and succinct representations of common human diseases by relating anatomical changes to the functional and clinical manifestations of disease and their underlying causes and mechanisms. Updated throughout, it offers a superb complement to more comprehensive textbooks and presentations of pathology, including course syllabi. It can also be used as an adjunct for study of gross and microscopic pathology specimens in laboratory exercises, and makes a great review resource for students, medical residents, physicians and other healthcare professionals. Grasp and retain key pathologic concepts and conditions. Beginning with a concise summary of the various pathological processes and diseases, each chapter consists of illustrations of pathological processes and diseases accompanied by concise text aimed at clarifying and expanding the information presented in the illustrations. Gain a superb visual understanding through more than 380 classic Netter and new Netter-style images, gross and microscopic photographs and tables. Reference information effortlessly with numerous tables throughout including 452 figures and 255 slides. Take your learning farther with Student Consult access.

Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management. New seventh edition highlights: Review questions and answers in each chapter prepare students for course and board exams. New contributors include cardiology fellows and internal medicine residents, who worked closely with faculty to extend coverage of clinically pertinent issues for medical students. Updated content reflects the latest understanding of mechanisms of cardiac disease and technological advances. Classic student-friendly features: Full-color illustrations help readers visualize and quickly grasp key concepts. Medical imaging and color clinical photographs show real-world examples of many clinically relevant cardiovascular conditions. Introductory chapter outlines and end-of-chapter summaries provide organized, quick review of core information. Bonus online study tools: Animations help support understanding of complex, dynamic disease processes. Interactive question bank reinforces learning and improves retention.

Offering the most comprehensive collection of head and neck pathology specimens available in one reference, Gnepp's Diagnostic Surgical Pathology of the Head and Neck, 3rd Edition, is a must-have resource for pathologists in training and practice. This abundantly illustrated volume covers both common and rare disease entities of the entire head and neck area, with particular emphasis on differential diagnosis and diagnostic problems and pitfalls. Detailed text and a highly visual format help you improve turnaround time when diagnosing a specimen and facilitate clear communication of prognosis and therapeutic management options to surgical/medical colleagues. Covers key topics such as molecular aspects of disease, especially in reference to targeted therapy and personalized medicine; the latest classification and staging systems for head and neck diseases and disorders; and immunohistochemical features that help ensure diagnostic accuracy. Discusses new diagnostic biomarkers and their utility in differential diagnosis, as well as newly described variants and new histologic entities. Includes a new chapter on eye pathology. Incorporates new criteria as established by the 2017 World Health Organization classification of Head and Neck tumors and the 2017 World Health Organization classification of Endocrine organ tumors. Provides clinicopathologic correlations throughout to give you all the information you need to formulate a complete diagnostic report. Features more than 1700 full-color illustrations that capture the pathologic appearance of the full range of common and rare neoplastic and non-neoplastic lesions. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

The first edition of The Paris System for Reporting Urinary Cytology introduced a completely new paradigm for detecting bladder cancer by urine cytology. This system concentrated on defining morphological characteristics of the most clinically significant form of bladder cancer, High Grade Urothelial Carcinoma. This new approach has been widely accepted throughout the world, and has become part of the daily practice of cytology. Considering that the first edition of The Paris System (TPS) introduced a new model of urinary cytodiagnosis, verification and expansion of initial material and data were anticipated. Based on evolving knowledge and readership requests, the group of highly experienced authors have created a new edition of TPS. This second edition includes areas and issues not originally covered. A new chapter on urine cytology of the upper tract, a rarely addressed topic, has been introduced. Furthermore, the issue of cellular degeneration is discussed in the criteria of all diagnostic categories. Examples of standardized reports are included in each chapter. Most importantly, a separate chapter presents data defining the risk of malignancy (ROM) for each diagnostic category to inform clinical management. New high quality images augment those of the first edition to better illustrate diagnostic clues and potential pitfalls. In addition to chapters on diagnostic criteria, current concepts of pathogenesis of bladder cancer, specimen adequacy and preparation, and ancillary tests are covered in separate chapters. A bonus to the volume is a comprehensive history of urine as the earliest diagnostic sample of human disease, richly illustrated with artworks from major museums. Written by internationally recognized authorities, this comprehensive and evidence-based guide to urine cytology is supported by the newest data confirming the original concept and significance of diagnostic criteria defining High Grade Urothelial Carcinoma. TPS is an essential tool for anyone who is practicing urinary cytology, including cytotechnologists, pathologists-in-training and practicing pathologists. This book should find a place in every cytology laboratory throughout the world. The Concept has been endorsed by the American Society of Cytopathology, and the International Academy of Cytology.

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of normal histology of every organ system, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Normal Histology is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource. Covers all areas of normal histology, including introductory chapters on electron microscopy, immunohistochemistry and histochemistry, the cell, and the basic organization of tissues Includes important updates throughout, covering not only traditional normal histology, but also its morphologic spectrum (variant normal histology) as well as recent advances in immunohistochemistry that expand the spectrum of antigen expression in normal tissues Contains new images in over 50% of the chapters, including images of the most common abnormal findings in each organ system, helping provide direct contrast with adjacent normal histology (i.e., what is normal and what is not) Provides the at-a-glance information necessary for diagnosis or adequacy evaluation at the time of procedure, using a concise, synoptic writing style Features more than 2,100 print and online images, including carefully annotated photomicrographs, gross images, electron micrographs, and full-color medical illustrations to help practicing and in-training pathologists reach a confident diagnosis Employs consistently templated chapters, bulleted content, key facts, a variety of test data tables, annotated images, and an extensive index for quick, expert reference at the point of care An eBook version is included with purchase. Giving you the power to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

This issue of Clinics in Laboratory Medicine, guest edited by Drs. Nicole V. Tolan and Robert Nerenz, will cover Direct to Consumer Testing: The Role of Laboratory Medicine. This issue is one of four selected each year by our Editor-in-Chief, Dr. Milenko Jovan Tanasijevic. Topics discussed in this issue will include: Health Literacy, Identifying Valuable Tests, Challenges with At-Home and Mail-In Direct-to-Consumer Genetic Testing, Self-Ordering and Interpretations, American Association for Clinical Chemistry Direct-to-Consumer Genetic Testing Position Statement, Data Disjunction, Integration of At-Home Testing, Wearable Devices, Oncogene Panels and Risk Calculations, Ethics, and Pharmacy's Integration and Testing Offered, among others.

Selected as a Doody's Core Title for 2022! Focusing on the essential information you need to know for the clinical practice of surgical pathology, this award-winning volume in the Lippincott Manual series provides concise, high-yield content that reflects today's fast-changing advances in the field. In one convenient, portable resource, you'll find complete coverage of surgical pathology for every organ and anatomic site -all at your fingertips for quick review and reference. Washington Manual of Surgical Pathology, 3rd Edition, is an ideal reference for surgical pathologists at all levels of training and practice. Includes new WHO classifications and access to more than 2,700 high-quality images online. Offers brief, logical approaches to gross examination and dissection; microscopic diagnosis of medical as well as surgical diseases; and tumor classification. Features separate chapters devoted to ancillary surgical pathology techniques, including immunohistochemistry, immunofluorescence microscopy, electron microscopy, frozen section diagnosis, flow cytometry, DNA and RNA based molecular methods, and imaging technologies. Presents valuable content in a concise, practical format that includes easy-to-follow guidelines, tables, diagrams, and algorithms. Previous edition winner of the BMA Medical Book Award First Prize in Pathology. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook , powering your content with natural language text-to-speech.

Microbial pathogenesis is the study of the mechanisms by which microbes (bacteria, viruses, protozoa, and multicellular parasites) cause infectious disease and make their hosts (humans) ill. Bacterial infections we thought were easily treatable are again a huge cause for concern with the well-publicized rise of antibiotic resistance. There are very few effective antiviral drugs and we live with the threat of epidemics such as bird flu and the outbreaks of viruses such the recent (and ongoing) Ebola crisis. Parasitic diseases such as malaria continue to pose a heavy burden in the developing world and with climate change could spread into the developed world. There is therefore an urgent need to understand microbial mechanisms, with research programmes and university courses dedicated to the subject.

Learn how to accurately analyze urine and body fluids with Fundamentals of Urine and Body Fluid Analysis, 5th Edition. Known for its clear writing style, logical organization, and vivid full-color illustrations, this renowned text offers the perfect level and depth of information for understanding the fundamental principles of urine and body fluids frequently encountered in the clinical laboratory. This includes the collection and analysis of urine, fecal specimens, vaginal secretions, and other body fluids such as cerebrospinal, synovial, seminal, amniotic, pleural, pericardial, and peritoneal fluids. Author Nancy Brunzel also shares her extensive knowledge and expertise in the field as she highlights key information and walks you through essential techniques and procedures - showing you how to correlate data with your knowledge of basic anatomy and physiology in order to understand pathologic processes. Study questions and case studies in each chapter reinforce comprehension and application, with an answer key located in the back of the book. UNIQUE! Table of crystal images based on shape serves as a single, comprehensive guide to the identification of crystals in urine sediment. UNIQUE! Image Gallery of Urine Sediment provides alternate views of sediment components to augment the numerous classic photomicrographs already present in the Microscopic Examination of Urine chapter. UNIQUE! Quick Guides to urine and body fluid photomicrographs make it fast and easy to find a photo of a specific cell type or component of interest. UNIQUE! Tables with high quality polarizing microscopy photomicrographs demonstrate the differences in birefringent intensity of substances with and without a red compensator. The most complete collection of high-quality, full-color images enables optimal identification of microscopic components in urine and other body fluids. NEW! Fully updated content provides valuable information on the latest techniques and advances in the field. NEW! Enhanced content, new tables, and new images facilitate the microscopic differentiation of monocytes, macrophages, and mesothelial cells in pleural, peritoneal, and pericardial fluids. NEW! More than 250 photomicrographs of cells and other components in body fluid and urine sediment serve as a visual quick reference for identification during analysis. NEW! Thumbprint images embedded in numerous tables enhance learning and serve as an invaluable resource when performing fluid analysis at the bench.

Filled with highly instructional visual images, An Atlas of the Clinical Microbiology of Infectious Diseases, Volume 1: Bacterial Agents contains typical and atypical presentations and identifying characteristics of microorganisms, including newly described microbial agents, covering the breadth of clinical microbiology. The book presents more than 425 color photomicrographs harvested over the author's 40-year career augmented by up-to-date text describing each microbial entity included and offering insightful comments on their clinical significance.

This book is intended for urologists and pathologists who practice in an office setting. In this setting, bladder and prostate diseases are most commonly encountered. Therefore, bladder and prostate biopsy and urine cytology specimens are frequently obtained by urologists, which require pathologists assistance to interpret. In the office setting, communication between urologists and pathologists becomes feasible, which is paramount for accurate diagnosis and better patient management. For this purpose, this book includes clinically relevant information for pathologists, concise pathology terminology, and diagnostic tests for urologists. This book describes the common clinical and pathological entities, and is written in a bullet format for easy and quick reference. For visual review, over 150 diagrams, histologic images, and other images are included. The first and second chapters describe bladder and prostate diseases, focusing on clinical-pathological correlation. Therefore, this book is also useful for pathology and urology residents in training, in preparation for board examination(s), or as a refresher reference for recertification. The third chapter is dedicated to office-based pathology laboratory services, which outlines laboratory instrumentation, procedures, and regulatory requirements. This information is useful for urologists and pathologists who are involved in the management of an office-based pathology laboratory. Finally, I greatly appreciate Josephine Wu DDS, Esq. and Miao Cui MD, MS, who contributed to this excellent third chapter.

Closely mirroring the daily sign-out process, Atlas of Pulmonary Pathology: A Pattern Based Approach is a highly illustrated, efficient guide to accurate diagnosis. This practical reference uses a proven, pattern-based approach to clearly explain how to interpret challenging cases by highlighting red flags in the clinical chart and locating hidden clues in the slides. Useful as a daily "scope-side guide," it features numerous clinical and educational features that help you find pertinent information, reach a correct diagnosis, and assemble a thorough and streamlined pathology report. More than 1,600 high-quality photomicrographs capture the subtle morphologic spectrum of both neoplastic and non-neoplastic lung biopsies. Each image is captioned with key diagnostic considerations and includes callouts showing subtle features and diagnostic clues. Practical tools throughout the text include: Tables that emphasize salient clinicopathologic features, management implications, and therapeutic options Discussions of how and when to incorporate molecular tools Checklists for key elements of the diagnostic approach and sample notes for inclusion in pathology reports Relevant endoscopic images, photographs of select gross specimens, and medical figures Brief reviews of normal histology that provide contrast to succeeding patterns "Pearls and Pitfalls" and "Near Misses" sections with lessons from real life sign-out experience "Frequently Asked Questions" sections that discuss common diagnostic dilemmas "Sample Note" sections that offer a template of how to sign out cases from the simple to the complex Comprehensive quiz provides experience with high-yield, board-style teaching topics Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

With other texts written at either too high or too low a level, this book meets the needs of PTA students for usable, understandable pathology related to clinical application. Extensively illustrated, this book allows students to more easily comprehend and maintain interest in otherwise complicated pathological processes. The fourteen chapter format effectively fits within a chapter per week course structure, or each chapter may be used as a stand alone module within any course. And as your students prepare to graduate, encourage them to keep this book to use as a clinically relevant reference as practicing PTAs!

Constituting a large percentage of everyday diagnostic practice, melanocytic pathology is a complex and challenging area with many difficult-to-diagnose lesions. This highly illustrated reference, written by three of the world's leading dermatopathologists, provides authoritative guidance in the accurate diagnosis of even the most challenging pigmented skin tumors, helping you avoid pitfalls and recognize mimics. Covers nearly every variant of melanocytic tumors you're likely to see. Emphasizes how to arrive at an efficient, accurate diagnosis, and includes dermoscopic findings for optimal diagnostic precision. Discusses modern analytic techniques (cytogenetics, molecular studies) and how to use them for diagnosis. Includes numerous case examples to illustrate the differential diagnoses and work-up; how to use ancillary techniques, along with their pros, cons, and limitations; and clinical follow-up. Presents the knowledge and experience of Klaus Busam, Pedram Gerami, and Richard Scolyer, - three dermatopathologists who are globally renowned for their expertise in melanoma pathology and analysis of melanocytic tumors by modern ancillary diagnostic techniques. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This powerful, easy-to-use resource presents the essentials of pathology in the popular Board Review Series outline format that highlights the most tested topics for the USMLE Step 1. Packed with new content; high-yield topics; concise descriptions; more than 450 USMLE-style questions with complete answers and explanations; and full-color illustrations, photomicrographs, and radiologic images, BRS Pathology, Sixth Edition, provides everything needed for course success and board exam prep. An easy-to-scan outline format with bolded key terms and summary tables enables concise review and exam preparation. Chapter-ending exams focus on high-yield, clinical content. An end-of-book Comprehensive Exam helps students gauge their mastery of key topics. New cross-references in the answers to the Comprehensive Exam use an outline format (section number/letter) to facilitate efficient study and easy linking in all formats. Many new full-color photomicrographs and schematic illustrations provide visual learning and review. Key topic icons help students quickly locate important content. An online interactive question bank features all the questions from the book for anytime, anywhere test preparation and review. eBook available for purchase. Fast, smart, and convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more