Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
|
Your cart is empty |
|||
Books > Science & Mathematics > Biology, life sciences > Molecular biology
Melioidosis is an endemic tropical disease and is fast becoming an emerging global concern. Its clinical mimicry with several other common diseases has made its diagnosis and treatment difficult. This book identifies a gap in the literature and represents the management and diagnosis of this fatal but curable disease. It provides detailed coverage of its history, epidemiology, the latency of the agent, pathogenesis, manifestations, clinical clues for detection, microbiological diagnosis, treatment, prevention, and environmental aspects. This book is for clinicians, infectious disease specialists, microbiologists, and public health professionals, in countries where melioidosis is endemic. Key Features: * Provides practical guidance on clinical diagnosis, management, and prevention of melioidosis. * Features high quality radiological and clinical photographs for clinicians and professionals. * Explores the latest techniques and advancements in laboratory diagnosis.
High-Density Sequencing Applications in Microbial Molecular Genetics, Volume 612 in the Methods of Enzymology series provides the latest on the high-density sequencing of DNA and cDNA libraries and how they have revolutionized contemporary research in biology. Methods permitting tens of millions of sequence reads in a single experiment have paved the way to genome-wide studies that are contributing to our understanding of the complexity of living systems. Chapters in this updated volume include Characterizing the role of exoribonucleases in the control of microbial gene expression: Differential RNA seq., Conformational studies of bacterial chromosomes by high-throughput sequencing methods, Measuring mRNA degradation, and more. Addition sections cover Global recognition patterns of bacterial RNA-binding proteins, High-resolution profiling of NMD targets, and the Generation of a metagenomic 3C/Hi-C library of human gut microbiota, Genome-wide mapping of yeast retrotransposons integration target sites, Measuring protein synthesis rates, Finding unsuspected partners of small RNAs with new screening approaches, Use of multiplexed transcriptomics to define the relationship between promoter sequence and transcription output, RNA-based control of quorum sensing in Vibrio cholerae, amongst other highly regarded topics.
Enzymes of Energy Technology, Volume 613 in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Chapters include Purification of fully active and crystallizable photosystem II from thermophilic cyanobacteria, Production and manipulation of [NiFeSe]-hydrogenases for renewable hydrogen research, Hydrogen production by [FeFe]-hydrogenases, Production and properties of enzymes that activate and produce carbon monoxide, Recombinant [NiFe]-hydrogenases from E. coli, Working with nitrogenase, Oxygen--tolerant [NiFe]-hydrogenases, Cytoplasmic and Membrane Bound Hydrogenases from the hyperthermophile Pyrococcus furiosus, and more. Additional sections cover Enzymatic conversion of methane into useful chemicals, Production and investigations of trans-membrane electron transfer protein, Characterization of post-translational modifications in methyl-coenzyme M reductase in diverse methanogens by mass-spectrometry, Reductive activation of carbon dioxide by formate dehydrogenases, and Lytic polysaccharide monooxygenases in biofuel processing. 14. Production and manipulation of blue copper oxidases for technological applications Yasmina Mekmouche
Progress in Molecular Biology and Translational Science, Volume 160 provides the most topical, informative and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series gives in-depth knowledge on the important molecular biological aspects of organismal physiology and function, along with insights on how this knowledge can be applied to understand and ameliorate human disease. This updated release covers Clinical Drugs in the Environment, Group I Intron Trans-Splicing, Adult Stem Cells on Regenerative Therapy, CRISPR in Animals and Animal Models, The Role of 3'-5'Exoribonucleases in RNA Degradation, and more.
Illnesses resulting from foodborne pathogens occur at least 6 million times each year and cause an estimated 9,000 deaths. For decades, food microbiologists have developed various effective methods of food protection. However, the constant development of multi-facet food processing technologies and the emergence of potent foodborne pathogens, compromised the efficacy of many antimicrobial interventions. Most technologies also fail to address the problem of bacterial debris remaining on the food surface. Furthermore, some bacteria have the ability to develop resistance to antimicrobial interventions. All such factors contribute to the continuously growing concern of keeping our food safe. Lactoferrin: Natural o Multifunctional o Antimicrobial presents the scientific background on use of this naturally occurring microbial blocking agent as an effective food antimicrobial intervention. THE SOURCE FOR APPLIED SCIENTIFIC INFORMATION ON LACTOFERRIN AS A NATURAL ANTIMICROBIAL INTERVENTION Lactoferrin: Natural o Multifunctional o Antimicrobial details microbial blocking technology to protect foods from harmful microbes. Recently, researchers at the Center for Antimicrobial Research, California State Polytechnic University at Pomona found that lactoferrin, when activated, functions as a potent antimicrobial intervention. It protects food by removing harmful bacteria from the surface, and by starving bacteria before they can multiply and produce harmful toxins and it also prevents bacteria from re-attaching to food surfaces. As a result this substance has potential to help the agribusiness and food industry supply safer food products to consumers. WHY LACTOFERRIN? Studied for 50 years, lactoferrin is known to have many beneficial biological properties as an integral component of the mammalian innate defense system. Lactoferrin is a broad-spectrum antimicrobial known to inhibit proliferation of bacteria, viruses, fungi, and parasites. Some of its current applications include: dietary supplement, ingredient in infant formula, and a medical treatment to boost the immune system. Because lactoferrin occurs naturally in milk products, it has a long track record of being safely consumed by humans. Convenient and affordable, lactoferrin could revolutionize the field of food antimicrobial science and technology and the way we protect ourselves from foodborne pathogens.
Modern Approaches in Drug Discovery, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Target Identification and Validation, Cell Painting/High Content Imaging, Target ID using chemical probes, Mining the microbiome for targets, Data driven approaches for diversity and drug-likeness, Affinity-based screening, Fragment screening (X-ray), Array-based approaches, Hit-to-lead: assessment and improvement of drug-like properties, Hit assessment and prioritization, Lead Optimization: fine tuning and risk mitigation, and more.
Biology of T Cells: Part A, Volume 341, the latest release in the International Review of Cell and Molecular Biology, reviews and details current advances in cell and molecular biology. The IRCMB series maintains the highest standard by publishing timely topics authored by prominent cell and molecular biologists. Specialized topics in this release include TCR signaling: Molecules and mechanisms, TCR diversity: Purpose and generation, Transcriptional programs underlying T-cell differentiation and function, Surface phenotypes of CD8+ and CD4+ T cells, Co-stimulation and co-inhibition in CD8+ and CD4+ T cells, Regulated cell death and T cells, Molecular mechanisms behind T-cell priming by DCs, and more.
Darwin's Pangenesis and its Rediscovery Part B explores Darwin's Pangenesis, an expanded cell theory and unified theory of heredity and variation from over 150 years ago that strengthened his theory of evolution and explained many phenomena of life. Now, new discoveries on circulating DNA, mobile RNAs, prions and extracellular vesicles are providing striking evidence for the chemical existence of Darwin's imaginary gemmules. In addition, new evidence for the inheritance of acquired characters, graft hybridization, and many other phenomena that Pangenesis supposedly explains are progressing, and are hence explored in this comprehensive volume. Specific chapters in this new volume include Darwin and Mendel: The Historical Connection, Darwin's Pangenesis and Graft Hybridization, Darwin's Pangenesis and Medical Genetics, Darwin's Pangenesis and Certain Anomalous Phenomena, and Natural Selection and Pangenesis: The Darwinian Synthesis.
Medicinal Plant Responses to Stressful Conditions discusses the effects of multiple biotic and abiotic stressors on medicinal plants. It features information on biochemical, molecular, and physiological strategies used to mitigate or alleviate detrimental effects of biotic and abiotic stressors. The book contains chapters featuring medicinal plants of importance covering subjects including genomics, functional genomics, metabolomics, phenomics, proteomics, and transcriptomics under biotic and abiotic stress of medicinal plants and their molecular responses. It suggests exogenous application of different types of stimulants to enhance medicinal plant production in such conditions. Features: * Details all aspects of biotic and abiotic stressors in various important medicinal plant species. * Chapters cover evidence-based approaches in the diagnosis and management of medicinal plants under stressful conditions. * Includes information on ways to mitigate effects from high salinity, drought, temperature extremes, waterlogging, wind, high light intensity, UV radiation, heavy metals, or mineral deficiencies. A volume in the Exploring Medicinal Plants series, this book is an essential resource for plant scientists, botanists, environmental scientists, and anyone with an interest in herbal medicine
Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids, Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chip for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.
Italy, the birthplace of opera in the late sixteenth century, has
in recent decades seen remarkable and vital musical growth, with
composers as diverse as Luciano Berio and Nino Rota, Luigi Nono and
Sylvano Bussotti, Giacomo Manzoni, Bruno Maderna and Salvatore
Sciarrino. The musical theatre has figured prominently in the work
of Italian composers during this period, ranging from operas
conceived in a traditional mode to works of a Music Theatre
variety, and in style from popular to avant-garde.
The contributors present a coherent set of case studies of practices, technologies and strategies aimed at the isolation, investigation, manipulation, production, and uses of molecules including vitamins, hormones, blood products, antibiotics, and vaccines. These case studies examine how processes of molecularization were set in motion in the inter-war period, how they were used as a resource in the biomedical 'mobilization' of World War II, and how new alliances and strategies created as part of the war effort played a central role in the reorganisation of biomedicine in the post-war period.
Concentrating on proven data and adopting a structure-function approach, this text provides grounding for an intricate understanding of the molecular biology, physiological mechanisms, and routine clinical use in disease settings of colony-stimulating factors (CSFs). This edition includes eight additional chapters, with updates of recently-discovered and established CSFs, each indexed individually.
Microbes are widely used in large-scale industrial processes due to their versatility, easy growing cultivation, kinetic potential, and the ability to generate metabolites with a wide range of potential applications to various commercial sectors, such as the food, pharmaceutical and cosmetic industries, in addition to the potential for agriculture, biomedical, and several others. Among the metabolites of greatest commercial interest, and many obtained on an industrial scale, the wide range of enzymes, biofuels, organic acids, amino acids, vitamins, biopolymers, and many other classes of metabolites. This book is intended for Bioengineers, Biologist, Biochemist, Biotechnologists, microbiologist, food technologist, enzymologist, and related Professionals/ researchers. Explores recent advances in the valorization of agri-food waste Provides technical concepts on the production of various bio-products of commercial interest Discusses the main process conditions to overcome the difficulties of using waste as alternative raw materials Introduces technical-economic details on the advantages and disadvantages of exploring the waste recovery chain Explores the main technological advances in the recovery of residues in functional products
This book gives a comprehensive overview of recent advances in the valorization of agri-food waste and discusses the main process conditions needed to overcome the difficulties of using waste as alternative raw materials. It also discusses specific methodologies, opportunistic microbes for biomass valorization, the sustainable production of agri-food waste, as well as examines the assessment and management of bioactive molecules production from microbial-valorization of agri-food waste. The authors provide technical concepts on the production of various bio-products and their commercial interest including agri-food waste utilization in the microbial synthesis of proteins, the valorization of horticulture waste, the sustainable production of pectin via microbial fermentation, as well as other food and pharmacological applications. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals and researchers. Explores recent advances in the valorization of agri-food waste Provides technical concepts on the production of various bio-products of commercial interest Discusses the main process conditions to overcome the difficulties of using waste as alternative raw materials Introduces technical-economic details on the advantages and disadvantages of exploring the waste recovery chain Explores the main technological advances in the recovery of residues in functional products
Explores recent advances in the valorization of agri-food waste Provides technical concepts on the production of various bio-products of commercial interest Discusses the main process conditions to overcome the difficulties of using waste as alternative raw materials Introduces technical-economic details on the advantages and disadvantages of exploring the waste recovery chain Explores the main technological advances in the recovery of residues in functional products
The goal of this book is to present recent advances in the production of food ingredients from agro-industrial residues, as well as to explore the technological advances made to make these ingredients a commercial reality for the food industry, such as peptides, food pigments, and organic acids, among others, thereby expanding the potential of bioprocesses in the valorization of agro-industrial residues for the production of molecules of industrial importance. This book is intended for bioengineers, biologists, biochemists, biotechnologists, microbiologists, food technologists, enzymologists, and related professionals/researchers. Explores recent advances in the valorization of agri-food waste into food ingredients; Provides technical concepts on the production of various food ingredients of commercial interest Explore nonel technological advanced strategies of extraction of bioactive compounds from food wastes Presents important classes of food ingredients obtained from alternative raw materials Sustainable food waste resources and management strategies Different pretraetment technologies and green extraction methodologies to support green environment in circular economy concept. Challenges in applications of re-derived bioactive compounds from food wastes in food formulations
Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington's Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins - substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research.
International Review of Cell and Molecular Biology. Volume 336 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This updated volume includes specific chapters on Membrane trafficking in autophagy, Targeting the metabolism of leukemic cells, Autophagic flux in Alzheimer's disease, Transcriptional alterations associated with celiac disease, and the Regulation of antitumor immunity by IDO1, amongst other timely topics. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.
WNT Signaling, Volume 153, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series provides readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, along with insights into how this knowledge may be applied to understand and ameliorate human disease. Each volume is edited by an internationally recognized expert who selects contributors at the forefront of a field.
Increasing population and industrialization are the key pollutant contributors in water bodies. The wastes generated by industries are highly hazardous for humans and the ecosystem and require a comprehensive and effective treatment before being discharged into water bodies. Over the years, many up gradations have been introduced in traditional water treatment methods which were expensive and ineffective especially for removal of toxic pollutants. Phycoremediation has been gaining attention due to its mutual benefit in wastewater treatment and for valuable algae biomass production. Wastewater, especially sewage and industrial effluents, is rich in pathogenic organisms, organic and inorganic compounds and heavy metals that adversely affect human and aquatic life. Microalgae use these inorganic compounds and heavy metals for their growth. In addition, they also reduce pathogenic organisms and release oxygen to be used by bacteria for decomposition of organic compounds in a secondary treatment. In this book, the potential of microalgae in wastewater treatment, their benefits, strategies, and challenges are discussed. The increasing need of finding innovative, low-cost, low-energy, sustainable and eco-friendly solutions for wastewater treatment makes the publication of a book on phycoremediation timely and appropriate. Features: (1) Deals with the most emerging aspects of algal research with special reference to phycoremediation. (2) Studies in depth diversity, mutations, genomics and metagenomics study (3) An eco-physiology, culturing, microalgae for food and feed, biofuel production, harvesting of microalgae, separation and purification of biochemicals.
1. Focuses on these newly available antibacterial, their mechanism of actions, resistance, and spectrum of activities 2. Useful for Biologists, Bioengineers, Biochemist, Biotechnologists, Microbiologists, Food technologists, Enzymologists 3. Discusses new unexploited targets and strategies for the next generation of antimicrobial drugs for combating the drug resistance and emerging pathogens
This timely volume explores tissue-derived stem cells, summarizing and evaluating the current body of knowledge. Sixteen chapters cover hematopoietic, osteoblast, skeletal, cardiac, pancreatic, epithelial, corneal, hepatic, renal, testicular, ovarian, fingernail, hair follicle and other stem cells- discussing their individual development, functions and pathologies, as well as the commonalities and interdependence between niches. This installment of the popular Stem Cell Biology and Regenerative Medicine series delivers authoritative, international perspectives on this rapidly growing field. Tissue-Specific Stem Cell Niche is an ideal complementary volume to Biology of Stem Cell Niche and Adult Stem Cells, Second Edition and will be invaluable to clinicians and researchers working with stem cells as well as to postgraduate trainees who are studying them. |
You may like...
Dynamics of Visual Motion Processing…
Guillaume S. Masson, Uwe J. Ilg
Mixed media product
R4,440
Discovery Miles 44 400
Molecular Biology of the Cell
Bruce Alberts, Rebecca Heald, …
Hardcover
Analytical Techniques in Biosciences…
Chukwuebuka Egbuna, Kingsley C. Patrick-Iwuanyanwu, …
Paperback
R3,586
Discovery Miles 35 860
|