The AlInGaN and ZnO materials systems have proven to be one of the scientifically and technologically important areas of development over the past 15 years, with applications in UV/visible optoelectronics and in high-power/high-frequency microwave devices. The pace of advances in these areas has been remarkable and the wide band gap community relies on books like the one we are proposing to provide a review and summary of recent progress.

Topical and transdermal drug delivery systems (TDDs) have several advantages over traditional drug delivery methods, as they can be less invasive, more sanitary, more cost-effective, and may result in better patient compliance. TDDs play a significant role in therapeutics with a variety of preparations and approaches designed by expert formulation scientists. This volume integrates a wide variety of case studies, research, and theories to reveal their diversity and capture the novel approaches of transdermal and topical drug delivery employed by developers and content experts in the field. It provides an abundance of important information and state-of-the-art research on topical and transdermal drug delivery systems and addresses the basics of drug delivery systems, strategies to enhance permeation across membranes, and formulation and evaluation of diverse dosage forms. The volume presents an evaluation of the pros and cons of conventional drug delivery systems against TDDs and discusses the nuances of micro- and nano-systems in TDDs. The extraordinary packages of nano systems (vesicular systems, polymeric nanoparticles, nanoemulsion and dendrimers) are broadly discussed, and their applications are reviewed through a transdermal route. The book looks at TDDs and the main nanoparticles used in skin diseases and lesions of the aging, such as psoriasis, vitiligo, cancer, lesions of the aging and others. Chapters also discuss polymeric micelles in topical and transdermal delivery; microneedles; emulsion, nanoemulsion and microemulsion; TDDs in pulmonary drug delivery systems; nanoencapsulated nasal drug delivery systems; skin sensitivity and irritation testing for transposing transdermal drug delivery systems; and regulatory aspects of drug development for dermal products. Topical and Transdermal Drug Delivery Systems: Applications and Prospects will be a valuable resource for pharmaceutical scientists and researchers, industry professionals, and academicians and students of the pharmaceutical and biomedical sciences.

This book is intended for researchers who are interested in investigating the nanomechanical properties of materials using advanced instrumentation techniques. The chapters of the book are written in an easy-to-follow format, just like solved examples. The book comprehensively covers a broad range of materials such as polymers, ceramics, hybrids, biomaterials, metal oxides, nanoparticles, minerals, carbon nanotubes and welded joints. Each chapter describes the application of techniques on the selected material and also mentions the methodology adopted for the extraction of information from the raw data.
This is a unique book in which both equipment manufacturers and equipment users have contributed chapters. Novices will learn the techniques directly from the inventors and senior researchers will gain in-depth information on the new technologies that are suitable for advanced analysis. On the one hand, fundamental concepts that are needed to understand the nanomechanical behavior of materials is included in the introductory part of the book. On the other hand, dedicated chapters describe the utilization of advanced numerical modeling in understanding the properties of complex materials.
This book is useful for students and researchers from diverse backgrounds including chemistry, physics, materials science & engineering, biotechnology and biomedical engineering.It is well suited as a textbook for students andas a reference book for researchers."

This book explores the possibility of using micro/nanostructures formed on the doped ice surface as a novel separation platform. In addition, it provides comprehensive information on the nature of freeze-concentrated solutions (FCSs) and the ice/FCS interface, which play important roles in the natural environment and industrial processes alike. The book proposes a novel size-selective separation approach using channels formed on the doped ice surface. The separation is based on the physical interaction of analytes with channel walls, which is controlled by varying the channel width through temperature and dopant concentration changes. It also shows the precise control of the channel width to be in a range of 200 nm-4 m and demonstrates the size-selective separation of microspheres, cells, and DNA. The physicochemical properties of FCSs are measured to reveal the nature of the ice/FCS interface, and the zeta potentials of ice are measured by determining EOF rates in a microchannel fabricated in the ice. The deprotonation at OH dangling bonds and adsorption of ions are also discussed. The viscosities of FCSs confined in micro/nanospaces are evaluated by means of two spectroscopic methods. When an FCS is confined in small spaces surrounded by ice, the viscosity increases compared to that in a bulk solution. Interestingly, this viscosity enhancement occurs even though its size is on the micrometer scale. These parameters are essential to discussing the unique phenomena occurring in FCSs. This book provides an explanation of the scientific processes taking place in FCSs, and reveals the potential that frozen solutions hold as innovative micro/nanofluidic devices and reaction platforms.

This book highlights the latest advances in AFM nano-manipulation research in the field of nanotechnology. There are numerous uncertainties in the AFM nano-manipulation environment, such as thermal drift, tip broadening effect, tip positioning errors and manipulation instability. This book proposes a method for estimating tip morphology using a blind modeling algorithm, which is the basis of the analysis of the influence of thermal drift on AFM scanning images, and also explains how the scanning image of AFM is reconstructed with better accuracy. Further, the book describes how the tip positioning errors caused by thermal drift and system nonlinearity can be corrected using the proposed landmark observation method, and also explores the tip path planning method in a complex environment. Lastly, it presents an AFM-based nano-manipulation platform to illustrate the effectiveness of the proposed method using theoretical research, such as tip positioning and virtual nano-hand.

Filling the need for a single work specifically addressing how to use plasma for the fabrication of nanoscale structures, this book is the first to cover plasma deposition in sufficient depth.
The author has worked with numerous R&D institutions around the world, and here he begins with an introductory overview of plasma processing at micro- and nanoscales, as well as the current problems and challenges, before going on to address surface preparation, generation and diagnostics, transport and the manipulation of nano units.

The ability to arrange precisely designed patterns of nanoparticles into a desired spatial configuration is the key to creating novel nanoscale devices that take advantage of the unique properties of nanomaterials. While two-dimensional arrays of nanoparticles have been demonstrated successfully by various techniques, a controlled way of building ordered arrays of three-dimensional (3D) nanoparticle structures remains challenging. This book describes a new technique called the 'nanoscopic lens' which is able to produce a variety of 3D nano-structures in a controlled manner. This ebook describes the nanoscopic lens technique and how it can serve as the foundation for device development that is not limited to a variety of optical, magnetic and electronic devices, but can also create a wide range of bio-nanoelectronic devices.

This book presents the recent progress in the field of nanophotonics. It contains review-like chapters focusing on various but mutually related topics in nanophotonics written by the world's leading scientists. Following the elaboration of the idea of nanophotonics, much theoretical and experimental work has been carried out, and several novel photonic devices, high-resolution fabrication, highly efficient energy conversion, and novel information processing have been developed in these years. Novel theoretical models describing the nanometric light-matter interaction, nonequilibrium statistical mechanical models for photon breeding processes and near-field-assisted chemical reactions as well as light-matter interaction are also explained in this book. It describes dressed photon technology and its applications, including implementation of nanophotonic devices and systems, fabrication methods and performance characteristics of ultrathin, ultraflexible organic light-emitting diodes, organic solar cells and organic transistors.

Mesoscopic physics has made great strides in the last few years. It is an area of research that is attractive to many graduate students of theoretical condensed matter physics. The techniques that are needed to understand it go beyond the conventional perturbative approaches that still form the bulk of the graduate lectures that are given to students. Even when the non-perturbative techniques are presented, they often are presented within an abstract context. It is important to have lectures given by experts in the field, which present both theory and experiment in an illuminating and inspiring way, so that the impact of new methodology on novel physics is clear. It is an apt time to have such a volume since the field has reached a level of maturity. The pedagogical nature of the articles and the variety of topics makes it an important resource for newcomers to the field. The topics range from the newly emerging area of quantum computers and quantum information using Josephson junctions to the formal mathematical methods of conformal field theory which are applied to the understanding of Luttinger liquids. Electrons which interact strongly can give rise to non-trivial ground states such as superconductivity, quantum Hall states and magnetism. Both their theory and application are discussed in a pedagogical way for quantum information in mesoscopic superconducting devices, skyrmions and magnetism in two dimensional electron gases, transport in quantum wires, metal-insulator transitions and spin electronics.

Multiscale Dissipative Mechanisms and Hierarchical Surfaces covers the rapidly developing topics of hierarchical surfaces, roughness-induced superhydrophobicity and biomimetic surfaces. The research in these topics has been progressing rapidly in the recent years due to the advances in the nanosciences and surfaces science and due to potential applications in nanotechnology. The first in its field, this monograph provides a comprehensive review of these subjects and presents the background introduction as well as recent and new results in the area.

In this book, the term "electrochemical nanotechnology" is defined as nanoprocessing by means of electrochemical techniques. This introductory book reviews the application of electrochemical nanotechnologies with the aim of understanding their wider applicability in evolving nanoindustries. These advances have impacted microelectronics, sensors, materials science, and corrosion science, generating new fields of research that promote interaction between biology, medicine, and microelectronics.

This volume reviews nanotechnology applications in selected high technology areas with particular emphasis on advances in such areas. Chapters are classified under four different headings: Nanotechnology for energy devices - Nanotechnology for magnetic storage devices - Nanotechnology for bio-chip applications - Nanotechnology for MEMS/Packaging.

This book focuses the recent progress in nanophotonics technology to be used to develop novel nano-optical devices, fabrication technology, and advanced systems. It begins with a review of near-field excitation dynamics in molecules. Further topics include: wavelength up-converting a phonon-assisted excitation process with degenerate beams and non-degenerate beams in dye grains, a fabrication method of semiconductor quantum dots including self-assembly of InAs quantum dots based on the Stranski-Krastanov growth mode, single-nanotube spectroscopy and time-resolved spectroscopy for studying novel excitonic properties of single-walled carbon nanotubes. The striking features of ecxitons in the carbon nanotube, multiple-exciton states, and microfluidic and extended-nano fluidic techniques. These topics are reviewed by nine leading scientists. This overview is a variable resource for engineers and scientists working in the field of nanophotonics.

Smart Buildings: Advanced Materials and Nanotechnology to Improve Energy Efficiency and Environmental Performance presents a thorough analysis of the latest advancements in construction materials and building design that are applied to maximize building efficiency in both new and existing buildings. After a brief introduction on the issues concerning the design process in the third millennium, Part One examines the differences between Zero Energy, Green, and Smart Buildings, with particular emphasis placed on the issue of smart buildings and smart housing, mainly the ‘envelope’ and how to make it more adaptive with the new possibilities offered by nanotechnology and smart materials. Part Two focuses on the last generation of solutions for smart thermal insulation. Based on the results of extensive research into more innovative insulation materials, chapters discuss achievements in nanotechnology, bio-ecological, and phase-change materials. The technical characteristics, performance level, and methods of use for each are described in detail, as are the achievements in the field of green walls and their use as a solution for upgrading the energy efficiency and environmental performance of existing buildings. Finally, Part Three reviews current research on smart windows, with the assumption that transparent surfaces represent the most critical element in the energy balance of the building. Chapters provide an extensive review on the technical features of transparent closures that are currently on the market or under development, from so-called dynamic glazing to bio-adaptive and photovoltaic glazing. The aesthetic potential and performance limits are also be discussed.

Miniaturization has revolutionized human affairs by making possible inexpensive integrated electronic circuits comprised of devices and wires with sub-micrometer dimensions. These integrated circuits are now ubiquitous, controlling everything from our automobiles to our toasters. Continued miniaturization, beyond sub-micrometer dimensions, seems likely. And so we are compelled to explore science and technology on a new, yet smaller scale: the nanometer scale. This volume is a survey of the machinery and science of the nanometer scale. Its twenty-two contributing authors, drawn from many different disciplines including atomic physics, microelectronics, polymer chemistry, and bio-physics, delineate the course of current research and articulate a vision for the development of the nanometer frontiers in electronics, mechanics, chemistry, magnetics, materials, and biology. They reveal a world thirty years hence where motors are smaller than the diameter of a human hair; where single-celled organisms are programmed to fabricate materials with nanometer precision; where single atoms are used for computation, and where quantum chaos is the norm. Aimed at the level of comprehension of at least a junior- or senior-level undergraduate science (biology, chemistry, physics, or engineering) student, the book provides a survey of developments within the breadth of the nanotechnology field. The book is thus intended for both students and researchers in tunneling microscopy, polymer chemistry, bio-physics, atomic physics, electrical engineering, mechanical engineering, materials science, condensed matter physics, biology, lithography, and chaos. Mathematical derivations have been minimized, but not eliminted. The book contains many illustrations, some in color.

This book reviews the most recent developments of fluorescent imaging techniques for medicinal chemistry research and biomedical applications, including cell imaging, in vitro diagnosis and in vivo imaging. Fluorescent imaging techniques play an important role in basic research, drug discovery and clinical translation. They have great impact to many fields including chemical biology, cell biology, medical imaging, cancer diagnosis and treatment, pharmaceutical science, among others, and they have facilitated our understanding of diseases and helped to develop many novel powerful tools for imaging and treatment of diseases. This book will appeal to scientists from numerous fields such as chemistry, pharmaceutical science, biology, materials science, and medicine, and it will serve as a very useful and handy resource for readers with different levels of scientific knowledge, ranging from entry level to professional level.

This book presents a universal mass-production micro/nano integrated fabrication technology, which can be used to realize micro/nano hierarchical structures on Si-based materials and flexible polymeric materials. This fabrication technology has been systematically investigated by using experimental measurements, mechanism analyses, theoretical simulations and so on. Three common materials (i.e., silicon, PDMS and Parylene-C) with micro/nano hierarchical structures have been successfully fabricated, which also show several attractive properties. Furthermore, this book introduces this fabrication technology into microenergy field, and proposes several high-performance nanogenerators, of which practical applications have also been studied in commercial electronic device and biomedical microsystem.

Energetic ion beam irradiation is the basis of a wide plethora of powerful research- and fabrication-techniques for materials characterisation and processing on a nanometre scale. Materials with tailored optical, magnetic and electrical properties can be fabricated by synthesis of nanocrystals by ion implantation, focused ion beams can be used to machine away and deposit material on a scale of nanometres and the scattering of energetic ions is a unique and quantitative tool for process development in high speed electronics and 3-D nanostructures with extreme aspect radios for tissue engineering and nano-fluidics lab-on-a-chip may be machined using proton beams. This book will benefit practitioners, researchers and graduate students working in the field of ion beams and application and more generally everyone concerned with the broad field of nanoscience and technology.

The Mathematics and Topology of Fullerenes presents a comprehensive overview of scientific and technical innovations in theoretical and experimental studies. Topics included in this multi-author volume are: Clar structures for conjugated nanostructures; counting polynomials of fullerenes; topological indices of fullerenes; the wiener index of nanotubes; toroidal fullerenes and nanostars; C60 Structural relatives: a topological study; local combinatorial characterization of fullerenes; computation of selected topological indices of C60 and C80 Fullerenes via the Gap Program; 4valent- analogues of fullerenes; a detailed atlas of Kekule structures of C60. The Mathematics and Topology of Fullerenes is targeted at advanced graduates and researchers working in carbon materials, chemistry and physics.

Handbook of Modern Biophysics brings current biophysics topics into focus, so that biology, medical, engineering, mathematics, and physical-science students or researchers can learn fundamental concepts and the application of new techniques in addressing biomedical challenges. Chapters will develop the conceptual framework of the physics formalism and illustrate the biomedical applications. With the addition of problem sets, guides to further study, and references, the interested reader can continue to independently explore the ideas presented.Volume 5: Modern Tools of BiophysicsEditor: Thomas Jue, PhDIn Modern Tools of Biophysics, a group of prominent professors have provided insights into the tools used in biophysics with respect to the following topics: Wave Theory of Image Formation in a Microscope: Basic Theory and Experiments Computer Simulations and Nonlinear Dynamics of Cardiac Action Potentials Myoglobin and Hemoglobin Contribution to the NIRS Signal in Muscle Anomalous Low Angle X-Ray Scattering of Membrane with Lanthanides Recording of Ionic Currents under Physiological Conditions-Action Potential-Clamping and "Onion-Peeling" Techniques Patch Clamp Technique and Applications About the EditorThomas Jue is a Professor in the Department of Biochemistry and Molecular Medicine at the University of California, Davis. He is an internationally recognized expert in developing and applying magnetic resonance techniques to study animal as well as human physiology in vivo and has published extensively in the field of magnetic resonance spectroscopy and imaging, near-infrared spectroscopy, bioenergetics, cardiovascular regulation, exercise, and marine biology. He served as a Chair of the Biophysics Graduate Group Program at UC Davis, where he started to develop scholarly approaches to educate graduate students with a balance of physical-science/mathematics formalism and biomedical perspective in order to promote interest at the interface of physical science, engineering, mathematics, biology, and medicine. He continues to develop the biophysics curriculum, and the Handbook of Modern Biophysics represents an aspect of that effort.

This volume provides the latest developments in the field of surface science and technology based on diazonium coupling agents as well as their precursors (e.g. aromatic amines). It presents new concepts of surface chemistry of diazonium salts and discusses their novel and challenging applications. The latest advances on surface modification with diazonium salts are discussed and various promising alternative surface modifiers such as iodonium salts are examined. This book demonstrates the universality of diazonium salts in the surface treatment of classical and emergent materials and it will be a great tool for researcher and graduates working in this field.

This book is devoted to a wide range of problems concerning applications of nanomaterials and nanodevices as effective solutions to modern ecological problems. Leading experts in nanoscience and nanotechnology present the key theoretical, experimental and implementation issues related to the creation and utilization of novel nanoscale devices to help ensure ecological security. The authors discuss appropriate nanotechnologies for minimizing various types of risk: to human life, technogenic risk, or indeed terrorist threats. Particular emphasis is placed on defining and studying the required materials properties, and - in the field - on nanoscale devices for sensors and monitoring."

First volume of a 40-volume series on nanoscience and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Raman spectroscopy for the characterization of nanomaterials. Modern applications and state-of-the-art techniques are covered and make this volume essential reading for research scientists in academia and industry.

This book describes the forcefields/interatomic potentials that are used in the atomistic-scale and molecular dynamics simulations. It covers mechanisms, salient features, formulations, important aspects and case studies of various forcefields utilized for characterizing various materials (such as nuclear materials and nanomaterials) and applications. This book gives many help to students and researchers who are studying the forcefield potentials and introduces various applications of atomistic-scale simulations to professors who are researching molecular dynamics.

The book covers a range of topics dealing with emerging computing technologies which are being developed in response to challenges faced due to scaling CMOS technologies. It provides a sneak peek into the capabilities unleashed by these technologies across the complete system stack, with contributions by experts discussing device technology, circuit, architecture and design automation flows. Presenting a gradual progression of the individual sub-domains and the open research and adoption challenges, this book will be of interest to industry and academic researchers, technocrats and policymakers. Chapters "Innovative Memory Architectures Using Functionality Enhanced Devices" and "Intelligent Edge Biomedical Sensors in the Internet of Things (IoT) Era" are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.