Barbara Arrowsmith-Young was born with severe learning disabilities. As a child, she read and wrote everything backward, struggled to comprehend language, and was continually getting lost. But by relying on her formidable memory, she made her way to graduate school, where she chanced upon research that inspired her to invent cognitive exercises to fix her own brain. The Woman Who Changed Her Brain interweaves her personal tale with riveting case histories from more than thirty years of her work with both children and adults.
People with learning disorders have long been told that such difficulties are a lifelong condition. In clear and lucid writing, The Woman Who Changed Her Brain refutes that message, demonstrating with fascinating anecdotes that anyone with a learning disability can be radically trans-formed: Arrowsmith-Young is a living example. She founded the Arrowsmith School in Toronto in 1980 and then the Arrowsmith Program to train teachers to implement this effective methodology in schools all over North America.
This remarkable book by a brilliant pioneer deepens our understanding of how the brain works. Our brain shapes us, and this book offers clear and hopeful evidence of the corollary: that we can shape our brains.

The 4th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The relation between genetics and its effect on several diseases are thoroughly examined in this volume. This volume focuses on the sessions from the conference on Genetics and Neurodegenerative Diseases.

A former drug addict turned behavioural neuroscientist reveals how drugs work in the brain ― and what we can do to fight addiction.

Judith Grisel was a daily drug user when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey.

In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Delving into the science of one of the world’s most pressing health problems, she reveals what is different about the brains of addicts even before they first pick up a drink or drug, and highlights the changes that take place in the brain and behaviour as a result of chronic using.

With compassion and clarity, Grisel describes what drove her to addiction, what helped her recover, and her belief that a ‘cure’ for addiction will not be found in our individual brains but in the way we interact with our communities.

Modern populations are superficially aware of media potentials and paraphernalia, but recent events have emphasized the general ignorance of the sentient media. Advertising has long been suspected of cognitive manipulation, but emergent issues of political hacking, false news, disinformation campaigns, lies, neuromarketing, misuse of social media, pervasive surveillance, and cyber warfare are presently challenging the world as we know it. Media Models to Foster Collective Human Coherence in the PSYCHecology is an assemblage of pioneering research on the methods and applications of video games designed as a new genre of dream analogs. Highlighting topics including virtual reality, personality profiling, and dream structure, this book is ideally designed for professionals, researchers, academicians, psychologists, psychiatrists, sociologists, media specialists, game designers, and students hoping for the creation of sustainable social patterns in the emergent reality of energy and information.

This book explains in layperson's terms a new approach to studying consciousness based on a partnership between neuroscientists and complexity scientists. The author, a physicist turned neuroscientist, outlines essential features of this partnership. The new science goes well beyond traditional cognitive science and simple neural networks, which are often the focus in artificial intelligence research. It involves many fields including neuroscience, artificial intelligence, physics, cognitive science, and psychiatry. What causes autism, schizophrenia, and Alzheimer's disease? How does our unconscious influence our actions? As the author shows, these important questions can be viewed in a new light when neuroscientists and complexity scientists work together. This cross-disciplinary approach also offers fresh insights into the major unsolved challenge of our age: the origin of self-awareness. Do minds emerge from brains? Or is something more involved? Using human social networks as a metaphor, the author explains how brain behavior can be compared with the collective behavior of large-scale global systems. Emergent global systems that interact and form relationships with lower levels of organization and the surrounding environment provide useful models for complex brain functions.By blending lucid explanations with illuminating analogies, this book offers the general reader a window into the latest exciting developments in brain research.

The nematode C. elegans is one of the most important model organisms for understanding neurobiology. Its completely mapped neural connectome of 302 neurons and fully characterized and stereotyped development have made it a prototype for understanding nervous system structure, development, and function. Fifty-six out of C. elegans' total of 959 somatic cells are classified as neuroglia. Although research on worm glia has lagged behind studies focused on neurons, there has been a steep upswing in interest during the past decade. Information arising from the recent burst of research on worm glia supports the idea that C. elegans will continue to be an important animal model for understanding glial cell biology. Since the developmental lineage of all cells was mapped, each glial cell in C. elegans is known by a specific name and has research associated with it. We list and describe the glia of the hermaphrodite form of C. elegans and summarize research findings relating to each glial cell. We hope this lecture provides an informative overview of worm glia to accompany the excellent and freely available online resources available to the worm research community.

Neuroscience has made considerable progress in figuring out how the brain works. We know much about the molecular-genetic and biochemical underpinnings of sensory and motor functions. Recent neuroimaging work has opened the door to investigating the neural underpinnings of higher-order cognitive functions, such as memory, attention, and even free will. In these types of investigations, researchers apply specific stimuli to induce neural activity in the brain and look for the function in question. However, there may be more to the brain and its neuronal states than the changes in activity we induce by applying particular external stimuli. In Volume 2 of Unlocking the Brain, Georg Northoff addresses consciousness by hypothesizing about the relationship between particular neuronal mechanisms and the various phenomenal features of consciousness. Northoff puts consciousness in the context of the resting state of the brain thereby delivering a new point of view to the debate that permits very interesting insights into the nature of consciousness. Moreover, he describes and discusses detailed findings from different branches of neuroscience including single cell data, animal data, human imaging data, and psychiatric findings. This yields a unique and novel picture of the brain, and will have a major and lasting impact on neuroscientists working in neuroscience, psychiatry, and related fields.

This book discusses new candidates for rapid-acting antidepressants, such as (R)-ketamine, (2R,6R)-hydroxynorketamine, scopolamine, mGluR2/3 antagonists and AMPA receptor agonists. There are serious limitations to currently available antidepressants, such as delayed onset and low rates of efficacy. The discovery that a single dose of ketamine, an NMDAR antagonist, can produce rapid antidepressant effects that are sustained has led to new research in this area. In this volume, a variety of novel pharmaceutical treatments are examined. This volume would be useful to both researchers and clinicians who work in the field of pharmacology, specifically CNS drug treatments.

Neuroscience has made considerable progress in figuring out how the brain works. We know much about the molecular-genetic and biochemical underpinnings of sensory and motor functions, and recent neuroimaging work has opened the door to investigating the neural underpinnings of higher-order cognitive functions, such as memory, attention, and even free will. In these types of investigations, researchers apply specific stimuli to induce neural activity in the brain and look for the function in question. However, there may be more to the brain and its neuronal states than the changes in activity we induce by applying particular external stimuli.
In Volume 1 of Unlocking the Brain, Georg Northoff presents his argument for how the brain must code the relationship between its resting state activity and stimulus-induced activity in order to enable and predispose mental states and consciousness. By presupposing such a basic sense of neural code, the author ventures into different territories and fields of current neuroscience, including a comprehensive exploration of the features of resting state activity as distinguishable from and stimulus-induced activity; sparse coding and predictive coding; and spatial and temporal features of the resting state itself. This yields a unique and novel picture of the brain, and will have a major and lasting impact on neuroscientists working in neuroscience, psychiatry, and related fields.

SHORTLISTED FOR THE PHYSICS WORLD BOOK OF THE YEAR 2019 'One of the deepest and most original thinkers of his generation of cognitive scientists. His startling argument has implications for philosophy, science, and how we understand the world around us' Steven Pinker 'Is reality virtual? It's a question made even more interesting by this book' Barbara Kiser, Nature Do we see the world as it truly is? In The Case Against Reality, pioneering cognitive scientist Donald Hoffman says no? we see what we need in order to survive. Our visual perceptions are not a window onto reality, Hoffman shows us, but instead are interfaces constructed by natural selection. The objects we see around us are not unlike the file icons on our computer desktops: while shaped like a small folder on our screens, the files themselves are made of a series of ones and zeros - too complex for most of us to understand. In a similar way, Hoffman argues, evolution has shaped our perceptions into simplistic illusions to help us navigate the world around us. Yet now these illusions can be manipulated by advertising and design. Drawing on thirty years of Hoffman's own influential research, as well as evolutionary biology, game theory, neuroscience, and philosophy, The Case Against Reality makes the mind-bending yet utterly convincing case that the world is nothing like what we see through our eyes.

This book explores new developments in the dialogues between science and theatre and offers an introduction to a fast-expanding area of research and practice.The cognitive revolution in the humanities is creating new insights into the audience experience, performance processes and training. Scientists are collaborating with artists to investigate how our brains and bodies engage with performance to create new understanding of perception, emotion, imagination and empathy. Divided into four parts, each introduced by an expert editorial from leading researchers in the field, this edited volume offers readers an understanding of some of the main areas of collaboration and research: 1. Dances with Science 2. Touching Texts and Embodied Performance 3. The Multimodal Actor 4. Affecting Audiences Throughout its history theatre has provided exciting and accessible stagings of science, while contemporary practitioners are increasingly working with scientific and medical material. As Honour Bayes reported in the Guardian in 2011, the relationships between theatre, science and performance are 'exciting, explosive and unexpected'. Affective Performance and Cognitive Science charts new directions in the relations between disciplines, exploring how science and theatre can impact upon each other with reference to training, drama texts, performance and spectatorship. The book assesses the current state of play in this interdisciplinary field, facilitating cross disciplinary exchange and preparing the way for future studies.

Research on natural and artificial brains is proceeding at a rapid pace. However, the understanding of the essence of consciousness has changed slightly over the millennia, and only the last decade has brought some progress to the area. Scientific ideas emerged that the soul could be a product of the material body and that calculating machines could imitate brain processes. However, the authors of this book reject the previously common dualism-the view that the material and spiritual-psychic processes are separate and require a completely different substance as their foundation. Reductive Model of the Conscious Mind is a forward-thinking book wherein the authors identify processes that are the essence of conscious thinking and place them in the imagined, simplified structure of cells able to memorize and transmit information in the form of impulses, which they call neurons. The purpose of the study is to explain the essence of consciousness to the degree of development of natural sciences, because only the latter can find a way to embed the concept of the conscious mind in material brains. The book is divided into three parts. Part 1 works to convince readers that the emergence of consciousness does not require detailed knowledge of the structure and morphology of the brain, with the exception of some specific properties of the neural network structure that the authors attempt to point out. Part 2 proves that the biological structure of many natural brains fulfills the necessary conditions for consciousness and intelligent thinking. Similarly, Part 3 shows the ways in which artificial creatures imitating natural brains can meet these conditions, which gives great hopes for building artificially intelligent beings endowed with consciousness. Covering topics that include cognitive architecture, the embodied mind, and machine learning, this book is ideal for cognitive scientists, philosophers of mind, neuroscientists, psychologists, researchers, academicians, and advanced-level students. The book can also help to focus the research of linguists, neurologists, and biophysicists on the biophysical basis of postulated information processing into knowledge structures.

Neuroprosthetics is a fast-growing area that brings together the fields of biomedical engineering and neuroscience as a means to interface the neural system directly to prostheses. Advancing research and applications in this field can assist in successfully restoring motor, sensory, and cognitive functions. Emerging Theory and Practice in Neuroprosthetics brings together the most up-to-date research surrounding neuroprosthetics advances and applications. Presenting several new results, concepts, and further developments in the area of neuroprosthetics, this book is an essential publication for researchers, upper-level students, engineers, and medical practitioners.

There is a growing literature in neuroethics dealing with cognitive neuro-enhancement for healthy adults. However, discussions on this topic tend to focus on abstract theoretical positions while concrete policy proposals and detailed models are scarce. Furthermore, discussions appear to rely solely on data from the US or UK, while international perspectives are mostly non-existent. This volume fills this gap and addresses issues on cognitive enhancement comprehensively in three important ways: 1) it examines the conceptual implications stemming from competing points of view about the nature and goals of enhancement; 2) it addresses the ethical, social, and legal implications of neuroenhancement from an international and global perspective including contributions from scholars in Africa, Asia, Australia, Europe, North America, and South America; and 3) it discusses and analyzes concrete legal issues and policy options tailored to specific contexts.

The book highlights important new research approaches of clinical relevance, written by prominent researchers in the field of OCD and related disorders. A broad range of topics is covered, beginning with a description of the phenotypic features of the OCD followed by chapters on developmental aspects, animal models, genetic and biological models including neuro-inflammation, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered including clinical and pharmacogenetic treatment models. In this way the volume brings together the key disciplines involved in the neurobiological understanding of OCD to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators and clinicians interested in the present state of OCD research.