In the same way atomic structures explain the physical properties of an object, neuroscientists are now learning about the human mind by examining how the neurons in the brain are connected to one another and their surrounding environments. Will brain scientists ever be capable of reading minds? Why are certain things harder to remember than others? The Brain-Shaped Mind addresses these and other questions to provide a clear account of how the structure of the brain influences the workings of the mind. Naomi Goldblum is a lecturer in psychology at Bar-Ilan University in Ramat Gan, Israel. She has studied neuropsychology with a particular emphasis on cognitive psychology.

In the 1960s, Sydney Brenner proposed to use the nematode worm Caenorhabditis elegans to discover the control mechanisms of animal development and to reveal how a small number of neurons generate different behaviours, giving birth to a vibrant community that uses this animal model for their studies. Brenner was aided in his aim by John Sulston, who mapped the C. elegans cell lineages - from a single cell to the multicellular adult - which transformed the field of developmental biology. As a tribute to these two men, this book captures the perspectives of some of the early pioneers of the worm community, from Martin Chalfie, Robert Waterston and Donald Moerman to Catherine Rankin, Antony Stretton and John White. It also includes contributions from subsequent generations of the community, who explore the development and function of the C. elegans nervous system. This book features how this animal has become one of the best models for elucidating the biology of different sensory modalities and their complex behavioural outputs, or how this animal's survival strategies have contributed to our understanding of ageing and neurodegeneration. Thus, this volume documents the development of the C. elegans neuroscience field, from infancy to maturity. The chapters in this book were originally published as a special issue of the Journal of Neurogenetics.

Autobiographical memory is constituted from the integration of several memory skills, as well as the ability to narrate. This all helps in understanding our relation to self, family contexts, culture, brain development, and traumatic experiences. The present volume discusses contemporary approaches to childhood memories and examines cutting-edge research on the development of autobiographical memory. The chapters in this book written by a group of leading authors, each make a unique contribution by describing a specific developmental domain. In providing a multinational and multicultural perspective on autobiographical memory development-and by covering a variety of theoretical and methodological approaches, this state-of-the-book is essential reading on the autobiographical memory system for memory researchers and graduate students. It is also of interest to scholars and students working more broadly in the fields of cognitive, developmental, and social psychology, and to academics who are conducting interdisciplinary research on neuroscience, family relationships, narrative methods, culture, and oral history.

In this innovative and challenging book, William Pardridge, a world leader in the study of the blood-brain barrier and its clinical implications, argues that brain drug development has been restricted by the failure of adequate brain drug targeting. This is an increasingly urgent problem as developments in genomics lead to new generations of therapeutic macromolecules. The author reviews the field of neurotherapeutics from the point of view of drug targeting. He surveys the scientific and clinical basis of drug delivery across biological membranes, including topics such as genetically engineered trojan horses for drug targeting, antisense neurotherapeutics, and gene therapy of brain disorders. At a time when there are few significant new drug treatments in prospect for common neurological diseases, this authoritative review will encourage a wide range of clinicians and neuroscientists to reexamine the development and use of drugs in treating disorders of the central nervous system.

1. Explores the memory phenomena that confound and challenge standard theories of memory processing, including the deja vu phenomenon, tip-of-the-tongue states, unconscious plagiarism, and insight and creativity in memory. 2. Places memory quirks within the broader context of human memory, providing an alternative to traditional texts on human memory. 3. Features contributions from the leading researchers in the field.

This book comprehensively covers the molecular basis of stress responses of the nervous system, providing a unique and fundamental insight into the molecular, physiological and behavioral basis of the stress response of a whole organism. Edited by leading experts in the field and summarizing the latest research advances in this area, this ready reference is an invaluable resource for clinicians dealing with stress-related disorders, biomedical researchers working in the field as well as for pharmacology and biotech companies.

From the contents: Systems in Stress ResearchCells and CircuitsCognition and BehaviorImmune ResponsesPost-traumatic Stress DisorderVulnerability to Disease

Richly illustrated in attractive full-colour and contains pedagogical features such as essay questions, summary and key points, and further reading suggestions is supported by a fully updated companion website, featuring student resources including lecture recordings, multiple choice questions and useful web links, as well as PowerPoint slides for lecturers. The only dedicated textbook on social neuroscience providing a much needed resource for lecturers and students. Suitable for both undergraduate and postgraduate students in psychology and neuroscience from 2nd year to masters level. Relevant courses include social neuroscience, social cognitive neuroscience, the social mind, social cognition, human neuroscience, developmental social neuroscience, etc. The third edition will be updated to reflect the growing volume of evidence and theories in the field and will include additional content on the applications of social neuroscience, social influence, reproducibility issues, and computational approaches. The companion website will include a new test bank.

The field of educational neuroscience uses new insights about the neural mechanisms of learning to improve educational practices and outcomes. The first volume to bring together the latest knowledge on the development of educational neuroscience from a life-span perspective, this important text offers state of the art, authoritative research findings in educational neuroscience before providing evidence-based recommendations for classroom practice. Thomas, Mareschal, Dumontheil, and the team of expert international contributors assembled in this volume thoroughly explore four main themes throughout the book. The first theme is individual differences, or what makes children perform better or worse in the classroom. The second theme is the nature of individual differences at different stages in development, from early years into adulthood. The third theme addresses cognitive enhancement, summarizing research that has investigated activities that might give general benefits to cognition. And the fourth theme considers the translation of research findings into classroom practices, discussing broader ethical issues raised by educational neuroscience, and what teachers need to know about neuroscience to enhance their day-to-day practice. Specific topics explored include neuropsychological perspectives on socioeconomic disparities in educational achievement, reading difficulties, phonological skills, executive function, and emotional development. Educational Neuroscience is essential reading for researchers and graduate students of educational psychology, developmental science, developmental psychology, and cognitive psychology, especially those specializing in emotion regulation.

1. Explores the memory phenomena that confound and challenge standard theories of memory processing, including the deja vu phenomenon, tip-of-the-tongue states, unconscious plagiarism, and insight and creativity in memory. 2. Places memory quirks within the broader context of human memory, providing an alternative to traditional texts on human memory. 3. Features contributions from the leading researchers in the field.

This book brings together the behavioral, physiological, and neuroendocrine regulation of calcium. An understanding of how the brain orchestrates whole-body demands for calcium is introduced. The approach is one in which behavior in addition to physiology serves bodily maintenance. The book links basic and clinical literature surrounding calcium homeostasis, as a wide variety of clinical syndromes are tied to calcium metabolism. Because calcium is so important during life stages particular to women, an emphasis is placed on the relevance of calcium to women's health throughout the book, though not exclusively since calcium is fundamental to both sexes.

Some of the brightest minds in criminology who were nurtured on the strictly environmentalist paradigm of the 20th century have declared that biosocial criminology is the paradigm for the 21st century. This book attempts to unite this ever-growing field with the premier neurobiological theory of personality, otherwise known as reinforcement sensitivity theory (RST). Anthony Walsh places the highly variable number of biosocial approaches under a single theoretical umbrella, whilst providing a unique integrative framework. As the leading neurobiological theory of personality and behavior in psychology today, RST focuses around the age-old question of how naturally selfish social animals can achieve their wants and needs without alienating others in their social groups. RST posits that evolution has built into humans three interacting systems: the behavioral approach system; the behavioral inhibition system; and the fight/flight/freeze system. RST identifies the neurobiological and genetic functions underlying each system and has found a cascade of supporting evidence. Throwing new light on many areas of concern to criminologists, such as psychopathy, violence, ADHD, and schizophrenia, this book will be of interest to scholars and upper-level students in the field. Additional features such as Focus Boxes and diagrams delve into measurement techniques and brain areas.

Why do people's financial and economic preferences vary so widely? 'Nurture' variables such as socioeconomic factors partially explain these differences, but scientists have been discovering that 'nature' also plays an important role. This is the first book to bring together these scientific insights for a holistic view of the role of human biology in financial decision-making. Geneticists are now examining which genetic markers are associated with financial and economic preferences. Neuroscientists are now determining where in the brain financial decisions are made and how that varies between people. Endocrinologists relate the level of different hormones circulating in the body to financial risk-taking. Researchers are exploring how physiology and environmental conditions influence investment decisions, and how three types of cognitive ability play essential roles in investment success. This exciting and relevant work being done in these academic silos has generally not been transmitted among the scientific areas, or to industry. For the first time, this book integrates all these areas, explaining the myriad ways in which a person's biology influences their investing decisions. Financial analysts, advisors, market participants, and upper-level undergraduate and postgraduate students of behavioral finance, behavioral economics, and investing will find this book invaluable, enabling a deeper understanding of investors' decision-making processes. To further ensure this new material is accessible to students, PowerPoint slides are available online for instructors' use.

First published in 1985, Ethical Issues in Psychosurgery examines the continuing debate surrounding the treatment of psychiatric disorder by psychosurgery and its ethical implications. Psychosurgery represents a radical treatment and it therefore raises, in a particularly acute and challenging fashion, questions which are implicit In most therapy. The book offers a focussed study in bioethics, a model for bioethical inquiry, as well as introduction to some of the major problems in bioethics. These range from detailed discussions of informed consent, the sanctity of the brain, and the use of experimental therapies, to wider questions of social contract and professionalization. John Kleinig's balanced and informed treatment of the questions will make this book invaluable not only to those concerned with the philosophy of legal and medical ethics, but also to those in the fields of psychiatric practice and research.

Focusing on a public health problem affecting millions of people of all ages, the second edition of Concussive Brain Trauma: Neurobehavioral Impairment and Maladaptation reflects Dr. Rolland S. Parker's more than 25 years of neuropsychological practice and research in traumatic brain injury and stress, and his prior experience as a clinical psychologist. Unique in its coverage of the personality changes, family dysfunction, and stress that often occur in the wake of concussive brain trauma, this book uses case examples to illustrate persistent and acute alterations of consciousness, as well as cognitive, mood, personality, and social effects of head injury in order to guide appropriate treatment. With six additional chapters, this edition covers: Post-concussive syndrome, biomechanical causes of trauma, and acute and chronic phases of co-morbid brain and somatic injury The physiological basis for behavior and posttraumatic dysregulation of systems Disorders related to pain, sensation, and motor activities Headaches, consciousness, cognition, cerebral personality, and psychodynamic disorders Developmental effects of children's concussive injury Blast injuries characteristic of modern war Unfamiliar signs not included in the usual list of post-concussive symptoms With a firm multi-disciplinary foundation, this book aids the concerned practitioner in rendering a more complete and accurate assessment, recognizing gaps in prior documentation, and conducting a more complete examination to acquire omitted information. It also shows how to achieve the benefit of higher accuracy in assessing disability, planning rehabilitation, and offering compensation. The book stands alone as an in-depth, authoritative guide to closed head injury and traumatic brain injury.

Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology. It discusses neurotoxic agents, describes the methods for studying neurotoxic actions, covers factors affecting neurotoxicity, and includes the diagnosis and treatment of neurodegenerative disorders. Neurotoxicology is an excellent reference for graduate and medical students, researchers in neurotoxicology, regulatory toxicologists, industrial hygienists, and anyone who needs to understand the adverse affects of neurotoxic agents on the nervous system.

The startle response (as a result of a sudden, loud noise, for instance) is a reflex that is wired into the brain at a very basic level. Although everybody will exhibit such a reflex, the strength and quickness of the startle response is modified by a subject's underlying psychoneurological state. Therefore, the nature of this modification is now seen as an accurate, objective measure of very deep neurological processes. This book is the first comprehensive volume devoted to startle modification. It offers a unique overview of the methods, measurement, physiology, and psychology of the phenomenon, particularly modification of the human startle eyeblink. Many of the world's leading investigators in the field have made contributions to this volume. Coverage includes elicitation and recording of startle blink; issues in measurement and quantification; the neurophysiological basis of the basic startle response and its modification by attentional and affective processes; psychological processes underlying short and long lead interval modification (including prepulse inhibition); applications of startle modification to the study of psychopathology, including schizophrenia, affective disorders, and psychopathy and developmental processes; and relationships with ERPs and behavioral measures of information processing.

This authoritative volume contains 179 chapters by international experts on recent developments in our understanding of amyloid proteins, protein folding disorders, and new and proposed clinical trials in amyloidosis. Topics include detection and characterization techniques; biological functions; genetics; disorders, diagnosis, and treatments, including organ transplants and drug therapies; results from extensive clinical studies; and epidemiology. This is a valuable resource for clinicians who care for patients with systemic and localized forms of amyloidosis, and for researchers in biochemistry, neurobiology, and cell biology.

'A tour de force . . . an important, affecting and effective book' ALASTAIR CAMPBELL '[A] gorgeous and urgent book' STEVEN PINKER 'MENDING THE MIND reminds us that, despite our hazy understanding of depression, and despite the true horror of the illness, some hope for recovery remains' THE TIMES Sadness is an inevitable part of life, but for most people it will usually alternate or coexist with happy times. Clinical depression, on the other hand, is a mental disorder that causes torment and anguish. It has no moments of relief. It unhinges us from everything we thought we knew about the world and makes us strangers to those we love. It is the predominant mental-health problem worldwide, affecting more than 250 million people. More than a fifth of the population of the UK report symptoms of depression or anxiety. Yet how much do we really know of the condition and of ways to treat it? In MENDING THE MIND, Oliver Kamm recounts what it's like to be mentally ill with severe depression, and he details the route by which, with professional help, he was able to make a full recovery. His experience prompted him to find out all he could about a condition that has afflicted humanity throughout recorded history. He explains the progress of science in understanding depression, and the insights into the condition that have been provided by writers and artists through the ages. His message is hopeful: though depression is a real and devastating illness, the mind and its disorders are yielding to scientific inquiry, and effective psychological, psychiatric and pharmacological treatments are already available. Candid, revelatory and deeply versed in current scientific research, MENDING THE MIND sets out in plain language how the scourge of clinical depression can be countered and may eventually be overcome.

The purpose of this book is to use neuroscience discoveries concerning religious experiences, the Self and personhood to deepen, enhance and interrogate the theological and philosophical set of ideas known as Personalism. McNamara proposes a new eschatological form of personalism that is consistent with current neuroscience models of relevant brain functions concerning the self and personhood and that can meet the catastrophic challenges of the 21st century. Eschatological Personalism, rooted in the philosophical tradition of "Boston Personalism", takes as its starting point the personalist claim that the significance of a self and personality is not fully revealed until it has reached its endpoint, but theologically that end point can only occur within the eschatological realm. That realm is explored in the book along with implications for personalist theory and ethics. Topics covered include the agent intellect, dreams and the imagination, future-orientation and eschatology, phenomenology of Time, social ethics, Love, the challenge of AI, privacy and solitude and the individual ethic of autarchy. This book is an innovative combination of the neuroscientific and theological insights provided by a Personalist viewpoint. As such, it will be of great interest to scholars of Cognitive Science, Theology, Religious Studies and the philosophy of the mind.

The visual processes involved in moving, reaching, grasping, and playing sports are complex interactions. For example, the action of moving the head provides useful cues to help interpret the visual information. Simultaneously, vision can provide important information about the actions and their control. This becomes a reiterative process. This process, and the interactions between vision and action, are the foci of this volume. This book contains contributions from scientists who are leaders in each of the several facets of the subject. The editors consider simple types of action, such as moving the eyes and head and body, as one would do while looking around or walking, as well as complex actions such as driving a car, catching a ball, or playing ping-pong.

Religious capacity is a highly elaborate, neurocognitive human trait that has a solid evolutionary foundation. This book uses a multidisciplinary approach to describe millions of years of biological innovations that eventually give rise to the modern trait and its varied expression in humanity's many religions. The authors present a scientific model and a central thesis that the brain organs, networks, and capacities that allowed humans to survive physically also gave our species the ability to create theologies, find sustenance in religious practice, and use religion to support the social group. Yet, the trait of religious capacity remains non-obligatory, like reading and mathematics. The individual can choose not to use it. The approach relies on research findings in nine disciplines, including the work of countless neuroscientists, paleoneurologists, archaeologists, cognitive scientists, and psychologists. This is a cutting-edge examination of the evolutionary origins of humanity's interaction with the supernatural. It will be of keen interest to academics working in Religious Studies, Neuroscience, Cognitive Science, Anthropology, Evolutionary Biology, and Psychology.

Diagnostic Expertise in Organizational Environments provides a state-of-the-art foundation for a new paradigm in expertise research and practice. Skilled diagnosis is essential for accurate and efficient performance across a range of organizational contexts, including aviation, finance, rail, forensic investigation, firefighting, and medicine. However, it is also a complex process, subject to the abilities and experience of individual operators, the culture and practices of organizations, the relationships between operators, and the availability and usefulness of technology. As a consequence, diagnostic skills can be difficult to learn, maintain, and evaluate. This volume is a comprehensive approach that examines diagnostic expertise at the level of the individual practitioner, in the social context, and at the organizational level. The chapter authors comprise both academics and highly skilled practitioners so that there is a clear transition from understanding the problem of diagnostic skills to the implementation of solutions, either through redesign, training, and/or selection. It will appeal to those academics and practitioners interested and involved in this field and also prove useful to students of psychology, cognitive science education and/or computer interaction.

Prion-related diseases, known as transmissible spongiform encephalopathies (TSEs), are infectious, fatal neurodegenerative disorders for which there is no cure, treatment, nor even a means for early diagnosis. The horrific advent of Mad Cow Disease -- transmitted to humans through eating meat from steers sickened by bovine spongiform encephalopathy --brought prion-related diseases international attention. Exceptionally dramatic, these diseases progressively and inexorably destroy the cognitive, motor, and sensorial skills that are the essence of human beings. Prions: The New Biology of Proteins provides a well-organized overview of what is known about prion-related diseases. This comprehensive work reviews the symptoms, epidemiology, and neuropathology of the disease. It focuses on evidence supporting the idea that TSEs result from a novel disease mechanism: transmission by replication of the misfolding of a single protein in the absence of nucleic acids. Following this hypothesis, the book examines the structure, conversion, and mechanism of prion propagation and details its cellular biology. It explores the transmission, discusses the challenges involved with diagnosis, and considers various therapeutic avenues that are presently being explored. A cohesive volume that integrates the pioneering work of many researchers, this book is authored by Claudio Soto, an internationally renowned researcher whose innovative work has led to an increased understanding of the heretical biology of prions and the development of novel strategies for treating and diagnosing neurodegenerative diseases. As protein misfolding diseases are his specialty, Soto also looks at the phenomenon from a wider perspective. He examines other diseases that display folding aberrations, considers how commonly such aberrations occur in nature, and asks readers to open their minds to consider the impact of prions on broader areas of biology, public health, and biotechnological

This volume provides an integrative review of the emerging and increasing use of network science techniques in cognitive psychology, first developed in mathematics, computer science, sociology, and physics. The first resource on network science for cognitive psychologists in a growing international market, Vitevitch and a team of expert contributors provide a comprehensive and accessible overview of this cutting-edge topic. This innovative guide draws on the three traditional pillars of cognitive psychological research-experimental, computational, and neuroscientific-and incorporates the latest findings from neuroimaging. The network perspective is applied to the fundamental domains of cognitive psychology including memory, language, problem-solving, and learning, as well as creativity and human intelligence, highlighting the insights to be gained through applying network science to a wide range of approaches and topics in cognitive psychology Network Science in Cognitive Psychology will be essential reading for all upper-level cognitive psychology students, psychological researchers interested in using network science in their work, and network scientists interested in investigating questions related to cognition. It will also be useful for early career researchers and students in methodology and related courses.