Neoplasias (tumors) are uncontrolled and progressive new growths of tissue. Frequently physicians caring for patients with neoplastic diseases are confronted with kidney or fluid and electrolyte complications that occur as a direct consequence of the neoplastic process or its treatments. The nine expert essays in this practical and clinically-oriented volume address the origins and treatment of most of these complications. Includes references to recent and classic studies.

Book initiates with introductory material to hemodialysis technology and its historical evolution and later on divulging into the field of biomaterials. With this background, the book discusses selection criteria of a suitable biomaterial for synthesis of haemodialysis membranes along with illustration of a complete indigenous, low cost technology for spinning of haemodialysis fibres. Well illustrated description of instruments used for membrane characterization and biomedical engineering is also provided at suitable junctures to effectively present the concept including worked out examples. Present title can be a good textbook as well as a research material for membrane as well as biomedical engineering curricula and provides coverage for appropriate undergraduate and graduate students interested in hemodialysis membranes.

This book provides an evidence based guide to the management of common kidney conditions. Concise and highly structured chapters outline a diagnosis and treatment framework for kidney diseases encountered within daily practice. Particular attention is given to the management of chronic kidney disease, genetic kidney diseases, cardiovascular complications, haemodialysis, kidney cancer, peritoneal dialysis, and kidney transplantation. Management of Kidney Disease aims to improve outcomes for patients with kidney diseases and is relevant to trainee and practising nephrologists, as well as healthcare professional treating kidney diseases. Additional questions and answers via app: Download the Springer Nature Flashcards app free of charge and use exclusive additional material to test your knowledge.

This book will cover all aspects of hypertension and the manifestations of cardiovascular disease in the Asian population. Asia has the largest population of all the continents, and also has the largest number of people suffering from these diseases. Due to an expanding economy and increasing affluent lifestyles, their incidence is increasing at alarming rates - in fact, this continent is a ticking time bomb for HTN and CVD outbreaks. The book fills a large gap, as there are currently no volumes on this topic - and provides much-needed information for physicians not only in Asia but globally. Not only physicians, but also all related medical professionals and libraries will benefit from this book, to which renowned international experts contributed.

Urinary symptoms in women have a very high prevalence rate. While the storage function of the bladder is similar in both genders, voiding function has marked differences with obvious anatomic and physiological genitourinary distinctions. Despite all advances in contemporary diagnostics and imaging, female bladder outlet obstruction and urethral stricture disease remain a conundrum to be deciphered in clinical practice. It is also seen that the female voiding symptoms and bladder outlet obstruction are poorly understood entities; which is also evident from the fact that Urethral dilatation in women is still a widely practiced procedure. This book provides a comprehensive understanding of female voiding disorders leading to bladder outlet obstruction and helps identify the women who will actually need reconstructive surgeries. The book begins with what is normal female voiding and then goes on to describe the various definitions of female bladder outlet obstruction along with controversies in Urodynamic diagnosis . As the functional causes are more common than actual strictures, this book elucidates on the knowledge of each of these differentials with their basic understanding and treatment outline, further throwing knowledge on the anatomical causes like pelvic organ prolapse and female urethral stricture. A separate section is dedicated to female urethral surgical anatomy and urethral reconstruction for urethral stricture as well as pelvic fracture urethral injury in females.

This book is devoted to hypertension in children and adolescents, a clinical issue that - thanks to the strides made in several areas of pathophysiological and clinical research - has received growing interest in cardiovascular medicine over the last several years. Given the increasing prevalence of hypertension in children and adolescents, this book represents an important and useful tool to address what has become a significant public health issue. It covers a diverse range of topics, from advances in the definition of hypertension and the identification of new risk factors, to current treatment strategies. The book also presents an overview of the latest findings, including the clinical significance of isolated systolic hypertension (ISH) in youth, the importance of out-of-office and central blood pressure measurement, new methods for assessing vascular phenotypes, and clustering of CV risk factors. Gathering contributions by international experts and pursuing a practice-oriented approach, the book offers a valuable tool for cardiologists, pediatricians and nephrologists, as well as general practitioners.

This book describes the past, present and future of dialysis and dialysis-related renal replacement therapies so that the reader can acquire a firm grasp of the medical management of acute and chronic renal failure.

By becoming thoroughly conversant with the past and present of dialysis, a health care professional will be in a much better position to provide the best standard of care to patients suffering from renal failure. As the book highlights the unsolved operational obstacles in the field of renal replacement therapies, future innovators may be inspired to develop novel solutions to tackle these problems. This remarkable work is a must-read not just for health care providers in the dialysis industry, but for patients, dialysis equipment manufacturers as well as pharmaceutical companies.

Supportive Care for the Renal Patient Second Edition provides a comprehensive, evidence-based overview of supportive care for the nephrology patient. An international group of contributors emphasise the continuum of palliative care from the time of diagnosis through to end-of-life care and the issues surrounding withdrawal of dialysis. The book addresses the psychological impact of the disease, the importance of involving the patient in making decisions about their care, ethical considerations, the role of the family and the multidisciplinary team. This new edition includes two new chapters on conservative management of advanced kidney disease (AKD) and dialysis in the very elderly. The chapters covering non pain symptoms, advance care planning, quality of life, psychological and psychiatric consideration and end-of-life care have also be completely revised to include new evidence and current thinking. This book will be of particular interest to palliative care practitioners; nephrologists, who increasingly need to know more about palliative care; nurse practitioners, dialysis nurses, social workers, dieticians, and psychiatric consultants. ABOUT THE SUPPORTIVE CARE SERIES Supportive care is the multidisciplinary holistic care of patients with chronic and life-limiting illnesses and their families - from the time around diagnosis, through treatments aimed at cure or prolonging life, and into the phase currently acknowledged as palliative care. It involves recognising and caring for the side-effects of active therapies as well as patients' symptoms, co-morbidities, psychological, social and spiritual concerns. It also values the role of family carers and helps them in supporting the patient, as well as attending to their own special needs. Unlike traditional palliative care, which grew from the terminal care of cancer patients, supportive care is not restricted to dying patients nor to cancer. This series covers the support of patients with a variety of long-term conditions, who are currently largely managed by specialist medical teams in hospital and by primary care teams in community settings. Each volume therefore provides a practical guide to the supportive care of patients at all stages of illness. Series Editor: Sam H. Ahmedzai

The rapidly proliferating research on the human immunodeficiency virus (HIV), now well in its second decade, continues to generate new information at a rate heretofore unparalleled in medicine. As a direct result, the increasing variety of methods for the prevention, diagnosis, and treatment of HIV and AIDS has made it difficult for physicians to keep abreast of the optimal management approaches in the field. The HIV Manual is an immensely practical, accessible, and up-to-date summary of the wide range of clinically relevant information on HIV-infected adults. It deals with the key issues and frequently encountered problems in HIV clinical care, and includes a special section on the symptom-based approach to diagnosis. In addition, this concise reference contains several chapters discussing topics rarely covered in similar books on the subject, such as HIV testing, initial evaluation, future anti-HIV therapies, alternative therapies, and nutrition.
The format is specifically designed for the busy practitioner's convenience. Subheadings clearly outline the principal elements of each chapter and treatment regimens are encapsulated in boxes so that needed material can be located with ease. The diagnostic and treatment guidelines are easy to follow and even where a concensus on treatment is lacking, the authors have made recommendations based on the existing data. This manual is intended to serve the information needs of health professionals involved in the care and treatment of HIV-infected patients in the clinical setting. It will also provide an easy-to-read guide for the general reader interested in finding out more about the diagnosis and prevention of HIV and AIDS.

Zwischen Nierenerkrankungen und Niereninsuffizienz einerseits und onkologischen Erkrankungen andererseits bestehen komplexe wechselseitige Beziehungen. Die vielfachen Zusammenhange, die erforderliche Diagnostik und die therapeutischen Konsequenzen, die sich daraus ableiten, sind systematisch und fundiert in diesem Buch beschrieben. Nierenerkrankungen sind wichtige Komorbiditaten bei Krebserkrankungen, beeinflussen deren Verlauf und sind bei der Therapie zu berucksichtigen; maligne Erkrankungen wirken sich unmittelbar oder uber nephrotoxische Therapieverfahren auf die Funktion der Nieren aus. Die Wechselwirkungen bei einzelnen Nierenerkrankungen und den wichtigsten Tumorformen und -therapien werden gezielt in eigenen Kapiteln dargestellt.

This book bridges the gap between advances in basic biology and chemistry and technological applications in the field of toxicity assessments. It describes areas of progress in the laboratory and clinic and discusses aspects of cellular organelles. It also covers the basic principles and applications of modern toxicological tools such as transcriptomic, proteomic, and metabolomic approaches. The recent developments on molecular modeling and systems biology are described with an eye on the future establishment of virtual cell technology. Finally the clinical implications for the understanding of acute and chronic renal toxicity are studied.

Der medizinische Fortschritt, die immer komplexeren rechtlichen Vorschriften und nicht zuletzt die Forderung der Patienten nach mehr Transparenz in der Behandlung lassen die genaue Kenntnis operativer Risiken und die uneingeschrankte Aufklarung der Patienten fur den Arzt immer wichtiger werden.
Dieses Handbuch erleichtert die Orientierung durch:
- Erlauterung rechtlicher Aspekte der Patientenaufklarung,
- systematische Auflistung der Risiken bzw. moglichen Komplikationen bei urologischen Eingriffen,
- Anleitung zur korrekten und vollstandigen Patientenaufklarung.
Damit steht erstmals ein Nachschlagewerk fur die tagliche diagnostische und therapeutische Aufklarungsarbeit zur Verfugung."

This work offers a comprehensive reference guide to help clinicians in the field of Internal Medicine addressing common aspects of endocrinological disorders in their daily practice. The exponential growth in our knowledge of biomedicine calls for continuous multidisciplinary approaches across specialists and disciplines. In this volume, recognized experts in each given area explore the complex mechanisms linking endocrinological disorders to abnormalities of the cardiovascular system, kidney, liver and gastrointestinal tract, autoimmune, neuro-psychiatric, rheumatic, and dermatologic diseases. Aspects connected to critically ill and elderly patients are examined as well, helping to enhance daily interactions with the most fragile populations observed in clinical medicine. The individual chapters are designed to deliver timely information while explaining pathophysiological mechanisms with the help of figures, flow-charts, and updated guidelines. The book offers a unique and valuable resource for all clinicians, residents, specialists, and physicians involved daily in the management of complex and multidisciplinary systemic diseases.

We are currently facing an alarming obesity epidemic, with its well-known health consequences such as metabolic syndrome / type 2 diabetes, cardiovascular diseases, an increased incidence of certain types of cancer, musculoskeletal disorders and pulmonary diseases. Experimental and clinical evidence accumulated in recent years now suggests that obesity has also a major effect on renal structure and function. Since the adipocyte is considered a source of many hormones and cytokines, obesity has much more direct influences on renal function besides mediating hypertension: It can by itself induce renal disease such as focal segmental glomerulosclerosis, but also, more commonly, bring about progression of chronic renal diseases. The present volume is the first comprehensive compilation dedicated to this important topic, featuring discussions of pathophysiological as well as clinical aspects written by the leaders in this emerging field of research. It brings together pathophysiological concepts on how obesity influences renal structure and function, reviews the epidemiology of the problem and provides therapeutic suggestions. This publication is recommended for internists, nephrologists, hypertensiologists, cardiologists, and urologists treating patients with obesity and renal diseases. Furthermore, basic scientists such as renal physiologists, renal pathologists, pharmacologists, biochemists, and epidemiologists who want a comprehensive overview of the topic will also profit from this book.

This short and clear book has a different approach from others on the pathology of the kidney. Most texts consider each disease separately on the assumption that the diagnosis has been made. This text is more useful in practice and shows how a diagnosis can be given on a renal biopsy specimen when the clinical indication for the biopsy is known. There is guidance on differential diagnosis, with notes on other matters including pathogenesis, prognosis, and where relevant the historical background of common renal disorders. This interesting book will be helpful to pathologists and trainee pathologists who look at renal biopsy specimens, nephrologists, renal transplant surgeons and their trainees who take the specimens, medical students who will be the next generation to take and report the specimens, nurses in nephrology, dialysis and renal transplant units, and pharmacists and others dealing with people with diseases of the kidney.

In some countries such as the United States, kidney disease kills more people than cancers of the prostate or breast. In the United States for example there are over 15 million individuals with kidney disease. Translated to a worldwide basis, kidney disease of various aetiologies represent a significant burden on healthcare systems, affecting mortality, morbidity and also the family unit. It is therefore imperative that appropriate use is made of conventional, new and emerging biomarker platforms to aid diagnosis, treatment and an understanding of outcome measures. Biomarkers in Kidney Disease embraces a holistic approach by combining information on different conditions that affect the kidney and the use of biomarkers. Biomarkers are described in terms of conventional, new and emerging analytes, techniques, platforms and applications. It covers the latest knowledge and trends. New platforms are described which combine advances in biomedical sciences, physics, computing and chemistry.

Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into "when, why, what and how" of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed diagrammatic /pictorial step by step descriptions of the techniques and management of complications related to these procedures. This book presents an up to date, one-stop reference for anything pertaining to MIT of these pelvic disorders. Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse is designed for both the urologist and urogynecologist treating patients with urinary disorders and pelvic organ prolapse as well as for residents in training.

Revised in line with feedback from users of the first edition, this practical clinical resource boasts a worldwide array of contributors, including the most prominent pediatric nephrologists in the US.

Excellently illustrated with photomicrographs and clinical diagrams supporting the chapters, Clinical Pediatric Nephrology features expanded case histories relating to the discussion and management of renal disease thus ensuring that this is a highly useful reference tool for nephrologists and house officers in practice, as well as nephrology fellows in training.

Vesicoureteral Reflux offers a leading reference on the diagnosis and therapeutic approach to the pediatric patient with is a common disorder, found in 1-2% of children.Representing the first book on this topic, this comprehensive text covers in detail the etiology, diagnosis and managmenet of this disease. Pediatric urologists, Urologists, Nephrologists, Pediatric Surgeons and Pediatricians will benefit from this unique review. Content Level Professional/practitioner Keywords Familial - Genetic Factor - Reflux Nephropathy - Renal Failure - Urinary Tract Infection - Vesicoureteral Reflux Related subjects Nephrology - Pediatrics - Surgery - Urology

This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage in the general and the hypertensive population. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.

The leading textbook on the subject. A completely rewritten and up-to-date Fourth Edition, formerly edited by W. Drukker, F. M. Parsons and J. F. Maher.

Acute kidney injury (AKI) is a serious and as yet incompletely understood disorder in which sudden impairment of kidney function occurs secondary to one or more of a variety of underlying conditions. This disorder is very common in (elderly) ICU patients and is associated with very high mortality. Many of those who survive suffer from permanent kidney failure and other long-term morbidities, which may include cardiovascular disease and immune dysfunction. Epidemiologic evidence suggests that AKI is not a single disease, but a syndrome comprised of multiple, often coexisting, etiologies. Being usually part of multiorgan failure syndrome, it calls for multiple organ support therapy. The publication at hand contains sections on prerenal azotemia syndromes, dying 'of' or 'with' AKI, pathophysiology of sepsis-induced acute kidney injury, developments in prevention / treatment / rehabilitation, and renal support. Reporting the latest recommendations from experts, it provides valuable information for those that are interested in understanding the disorder and its treatment options.

This pathology atlas on CD-ROM consists of 22 CD-ROMS, each dedicated to one organ system (see list of titles). Three CD-ROMs have already been prepared, the others are scheduled to appear within the next two years. Each CD-ROM is basically an image database depicting the known lesions of a given organ system, a short description of the lesion as well as the international classification of the lesion. Three types of classification are available upon entering the programme: ICD-10, SNOMED, or ADICAP. The programm is in English or French clickable. The authors are soliciting pathologists from countries all over the world to help promote the series.