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Biomaterials Associated Infection - Immunological Aspects and Antimicrobial Strategies (Paperback, 2013 ed.)
Loot Price: R6,096
Discovery Miles 60 960
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Biomaterials Associated Infection - Immunological Aspects and Antimicrobial Strategies (Paperback, 2013 ed.)
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Biomaterials associated infection (BAI) is one of the most common
complications associated with implantation of any biomaterial
regardless of form or function. These infections usually involve
bacterial colonization and biofilm formation on the biomaterial
itself, rendering the infection impervious to antimicrobials and
host defenses. In addition, it is becoming increasingly clear that
infection of the surrounding tissues also plays an important role
in BAI, and that the infection may be influenced by the composition
and design of the implanted biomaterial. In this book, worldwide
leaders in the field address this critical problem in the
translation of biomaterials research into clinical practice. The
book begins with an emphasis on the latest research in the
pathogenesis of BAI from microbiological, immunological, and
materials science perspectives. The current state of the art in
antimicrobial activation of biomaterials through surface
modification and the incorporation of antimicrobial agents is then
discussed. In the concluding chapters, successful translation of a
selection of antimicrobial technologies from preclinical research
into clinical use is described alongside a discussion of the
utility of these devices and perspectives for future development.
This book is essential reading for researchers and clinicians who
are interested in understanding the fundamentals of BAI, the latest
in antimicrobial materials research, and the state of the art in
clinically available antimicrobial containing medical devices.
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