Cell Engineering and Regeneration (Hardcover, 1st ed. 2020)

This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.

General

Imprint:	Springer International Publishing AG
Country of origin:	Switzerland
Series:	Reference Series in Biomedical Engineering
Release date:	August 2020
First published:	2019
Editors:	Jeffrey M. Gimble • Darja Marolt Presen • Richard O.C. Oreffo • Susanne Wolbank • Heinz Redl
Dimensions:	235 x 155mm (L x W)
Format:	Hardcover
Pages:	800
Edition:	1st ed. 2020
ISBN-13:	978-3-319-08830-3
Categories:	Books > Medicine > Nursing & ancillary services > Biomedical engineering > General Books > Science & Mathematics > Physics > Applied physics & special topics > Medical physics Books > Science & Mathematics > Physics > Applied physics & special topics > Biophysics Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Books > Professional & Technical > Biochemical engineering > Biotechnology > General Books > Professional & Technical > Mechanical engineering & materials > Materials science > General
LSN:	3-319-08830-0
Barcode:	9783319088303

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