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Books > Medicine > Nursing & ancillary services > Biomedical engineering
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RNA Delivery Function for Anticancer Therapeutics (Hardcover)
Loot Price: R5,720
Discovery Miles 57 200
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RNA Delivery Function for Anticancer Therapeutics (Hardcover)
Series: Nanotechnology for Drugs, Vaccines and Smart Delivery Systems
Expected to ship within 12 - 17 working days
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This book presents an overview of the current status of translating
the RNAi cancer therapeutics in the clinic, a brief description of
the biological barriers in drug delivery, and the roles of imaging
in aspects of administration route, systemic circulation, and
cellular barriers for the clinical translation of RNAi cancer
therapeutics, and with partial content for discussing the safety
concerns. It then focuses on imaging-guided delivery of RNAi
therapeutics in preclinical development, including the basic
principles of different imaging modalities, and their advantages
and limitations for biological imaging. With growing number of RNAi
therapeutics entering the clinic, various imaging methods will play
an important role in facilitating the translation of RNAi cancer
therapeutics from bench to bedside. RNAi technique has become a
powerful tool for basic research to selectively knock down gene
expression in vitro and in vivo. Our scientific and industrial
communities have started to develop RNAi therapeutics as the next
class of drugs for treating a variety of genetic disorders, such as
cancer and other diseases that are particularly hard to address
with current treatment strategies. Key Features Provides insight
into the current advances and hurdles of RNAi therapeutics.
Accelerates RNAi, miRNAs, and siRNA drug development for cancer
therapy from bench to bedside. Addresses various modifications and
novel delivery strategies for miRNAs, piRNAs and siRNA delivery in
anticancer therapeutics. Explores the need for the interaction of
hematologists,cell biologists, immunologists, and material
scientists in the development of novel cancer therapies. Describes
the current status of clinical trials related to miRNA and
siRNA-based cancer therapy Presents remaining issues that need to
be overcome to establish successful therapies.
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