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The Molecular Biology of Photorhabdus Bacteria (Hardcover, 1st ed. 2017)
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The Molecular Biology of Photorhabdus Bacteria (Hardcover, 1st ed. 2017)
Series: Current Topics in Microbiology and Immunology, 402
Expected to ship within 12 - 17 working days
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This book provides an essential update on the startling array of
novel insecticidal toxins and drugs produced by the fascinating
bacterium Photorhabdus. The respective chapters describe everything
from the detailed molecular biology of the 'Toxin complexes' or
Tc's to the complexity of insect immune response in relation to
both the bacterium and its nematode vector. The volume covers both
primary (toxin production and regulation) and secondary (natural
product synthesis and regulation) metabolism and emphasises the
potential use of toxins and drugs in both agriculture and medicine.
It also discusses in detail two totally novel quorum sensing
mechanisms and the likely role of LuxR solos in sensing the
presence of different bacterial hosts. Lastly, the book explores
the unique case of P. asymbiotica, which seems to have evolved the
ability to infect both insects and humans. This synthesis proves
that Photorhabdus truly does offer a 'gold mine' for the discovery
of novel insecticidal proteins and novel natural products with
potential uses in agriculture and medicine alike.
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