Bioinorganic chemistry is an interdisciplinary research field which centers on metals in biology. Over the past few decades, advances in chemistry, biology as well as in spectroscopic methods have shed light on the role of copper in human pathologies and allowed the growing discovery of copper-containing biological systems. Following this trend, much effort is being constantly chanelled towards understanding these fundamental biological processes or enzymes. In addition, chemists are developing molecules to target copper or copper enzymes as therapeutic tools. On the other hand, inspired by the function of biological systems, small molecular weight complexes inspired by the active site of copper enzymes are being prepared and studied. These bioinspired complexes can function both as mechanistic tools and as functional catalysts for oxidative transformations.The seven chapters in this book, contributed by internationally recognized authors cover recent developments on these aspects illustrated by interdisciplinary fields from biology, chemistry, spectroscopy to bioinspired catalysis. It contains aspects ranging from human health issues (copper homeostasis in bacteria and the development of molecules as anticancer or antibacterial agents) to bioinspired catalysis.

Up to date, easy to use, and rich with vibrant illustrations, Lippincott (R) Illustrated Reviews: Cell and Molecular Biology, 3rd Edition, provides a highly visual presentation of essential cell and molecular biology with a focus on topics related to human health and disease. This engaging approach incorporates all of the most popular features of the bestselling Lippincott (R) Illustrated Reviews series, including abundant full-color illustrations, chapter summaries, and review questions that link basic science to real-life clinical situations. The updated, versatile 3rd Edition can be used for a standalone cell biology course in medical, health professions, or other graduate and upper-level undergraduate programs; as a review for course and board exams; or in conjunction with other Lippincott (R) Illustrated Reviews for a seamless integrated course. UPDATED! Revised content throughout-including updated unit overviews and chapter summaries-helps students master the latest cell and molecular biology knowledge. UPDATED! Clinical Application boxes reinforce key concepts and enrich students' understanding and clinical application capability. More than 250 full-color, annotated illustrations clarify complex processes and simplify study. Online animations and interactive review questions strengthen comprehension and retention.

Peptides and proteins are crucial biomolecules in life. The manifold functions they carry out range from molecular recognition and signaling to catalysis and immune response. However, the native systems are limited to a reduced toolbox of chemical functionalities as well as tridimensional structures. Widening these toolboxes could pave the way to engineer peptides and proteins with enhanced properties compared to their native counterparts and/or with structures and functions unprecedented in Nature. Advances in the chemical and biological synthesis of peptides and proteins, in computational tools, in molecular biology and in high-throughput screening methods are making this realm possible.This book aims to give an overview of the last developments in the field of peptide and protein engineering. It comprises a collection of chapters that span from the production of simple non-proteinogenic building blocks and peptidic scaffolds of different sizes and structures to more complex systems including peptide-based nanomaterials, enzymes and artificial metalloenzymes. Different strategies are described where chemical and biological tools have been developed and combined to attain the desired properties and sought functionalities.The diverse systems described in this book highlight the progress in this important field and represent the starting points for the development of functional biomolecules, biomaterials and hybrid systems capable of addressing key societal challenges of our times in relevant areas such health, environment and energy.