Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules Features interactive computer simulations, available online through a companion website at: http://www.uri.edu/pharmacy/faculty/rosenbaum/basicmodels.html Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications Reviews of the 1st edition: This is an ideal textbook for those starting out and also for use as a reference book ." (International Society for the Study of Xenobiotics) and I could recommend Rosenbaum s book for pharmacology students because it is written from a perspective of drug action ...Overall, this is a well-written introduction to PK/PD . (British Toxicology Society Newsletter)

This unique and engaging open access title provides a compelling and ground-breaking account of the patient safety movement in the United States, told from the perspective of one of its most prominent leaders, and arguably the movement's founder, Lucian L. Leape, MD. Covering the growth of the field from the late 1980s to 2015, Dr. Leape details the developments, actors, organizations, research, and policy-making activities that marked the evolution and major advances of patient safety in this time span. In addition, and perhaps most importantly, this book not only comprehensively details how and why human and systems errors too often occur in the process of providing health care, it also promotes an in-depth understanding of the principles and practices of patient safety, including how they were influenced by today's modern safety sciences and systems theory and design. Indeed, the book emphasizes how the growing awareness of systems-design thinking and the self-education and commitment to improving patient safety, by not only Dr. Leape but a wide range of other clinicians and health executives from both the private and public sectors, all converged to drive forward the patient safety movement in the US. Making Healthcare Safe is divided into four parts: I. In the Beginning describes the research and theory that defined patient safety and the early initiatives to enhance it. II. Institutional Responses tells the stories of the efforts of the major organizations that began to apply the new concepts and make patient safety a reality. Most of these stories have not been previously told, so this account becomes their histories as well. III. Getting to Work provides in-depth analyses of four key issues that cut across disciplinary lines impacting patient safety which required special attention. IV. Creating a Culture of Safety looks to the future, marshalling the best thinking about what it will take to achieve the safe care we all deserve. Captivatingly written with an "insider's" tone and a major contribution to the clinical literature, this title will be of immense value to health care professionals, to students in a range of academic disciplines, to medical trainees, to health administrators, to policymakers and even to lay readers with an interest in patient safety and in the critical quest to create safe care.

The book is a compilation of guidelines from various organizations such as Society of Nuclear Medicine & Molecular Imaging, European Association of Nuclear Medicine, American College of Radiology and International Atomic Energy Agency. The description of the procedures is simple, easy to understand and current. The aim of this book is: a) Nuclear medicine professionals can use this book as a quick reference about how a procedure is to be performed. The set of instructions given to patient before, during and after the procedure have also been included in each chapter. b) To educate general physicians about nuclear medicine procedures. The procedures are explained briefly with common indications and precautions. Normal and abnormal nuclear medicine images have also been included for quick comparison. c) To educate paramedical staff or healthcare professionals so that they send patients to nuclear medicine department after proper preparation. d) To educate patients who come for nuclear medicine procedure. e) To clarify apprehensions and doubts which arise in the mind of the patients.

As the global psychiatric community enters a new era of transformation, this book explores lessons learned from previous efforts with the goal of "getting it right" this time. In response to the common refrain that we know about and 'do' recovery already, the authors set the recovery movement within the conceptual framework of major thinkers and achievers in the history of psychiatry, such as Philippe Pinel, Dorothea Dix, Adolf Meyer, Harry Stack Sullivan, and Franco Basaglia.

The book reaches beyond the usual boundaries of psychiatry to incorporate lessons from related fields, such as psychology, sociology, social welfare, philosophy, political economic theory, and civil rights. From Jane Addams and the Settlement House movement to Martin Luther King, Jr., and Gilles Deleuze, this book identifies the less well-known and less visible dimensions of the recovery concept and movement that underlie concrete clinical practice.

In addition, the authors highlight the limitations of previous efforts to reform and transform mental health practice, such as the de-institutionalization movement begun in the 1950s, in the hope that the field will not have to repeat these same mistakes. Their thoughtful analysis and valuable advice will benefit people in recovery, their loved ones, the practitioners who serve them, and society at large.

Foreword by Fred Frese, "Founder of the Community and State Hospital Section of the American Psychological Association and past president of the National Mental Health Consumers' Association"

Stem Cells: A Short Course is a comprehensive text for students delving into the rapidly evolving discipline of stem cell research. Comprised of eight chapters, the text addresses all of the major facets and disciplines related to stem cell biology and research. A brief history of stem cell research serves as an introduction, followed by coverage of stem cell fundamentals; chapters then explore embryonic and fetal amniotic stem cells, adult stem cells, nuclear reprogramming, and cancer stem cells. The book concludes with chapters on stem cell applications, including the role of stem cells in drug discovery and therapeutic applications in spinal cord injury, brain damage, neurological and autoimmune disorders, among others. Written by a leader in the field, Stem Cells: A Short Course appeals to both students and instructors alike, appealing to academic enthusiasm for stem cell research and applications.

A Comprehensive Guide to Radiographic Sciences and Technology is a concise review of radiographic physics and imaging, perfect for students preparing for certification examinations such as the American Registry for Radiologic Technologists (ARRT). Aligned with the core radiographic science components of the current American Society of Radiologic Technologists (ASRT) curriculum, this up-to-date resource covers topics including radiation production and characteristics, imaging equipment, digital image acquisition and display, radiation protection, basic principles of computed tomography, and quality control. The guide begins with an overview of the radiographic sciences and technology, followed by detailed descriptions of the major components of digital radiographic imaging systems. Subsequent sections discuss the essential aspects of diagnostic radiography and computed tomography, including basic physics, imaging modalities, digital image processing, quality control, imaging informatics, and basic concepts of radiobiology and radiation protection. Throughout the book, concise chapters summarise the critical knowledge required for effective and efficient imaging of the patient while emphasising the important, yet commonly misunderstood, relationship between radiation dose and image quality. Written by an internationally recognised expert in the field, this invaluable reference and guide: Provides easy access to basic physics, techniques, equipment, and safety guidelines for radiographic imaging Reflects the educational requirements of the American Society of Radiologic Technologists (ASRT), the Canadian Association of Medical Radiation Technologists (CAMRT), the College of Radiographers (CoR), and other radiography societies and associations worldwide Offers a range of pedagogical tools such as chapter outlines, key term definitions, bulleted lists, practical examples, and links to current references and additional resources Includes charts, diagrams, photographs, and x-ray images A Comprehensive Guide to Radiographic Sciences and Technology is required reading for students in programs using ionizing radiation, those preparing for the ARRT and other global radiography certification exams, and practising technologists wanting to refresh their knowledge.

The definitive companion for medical science study and revision Medical Sciences at a Glance consolidates the scientific knowledge a student needs to know to provide a solid framework of key facts to build on. Concise, easy to follow, written specifically for medical students, and using the unique at a Glance style to convey key concepts, Medical Sciences at a Glance also demonstrates vital links between different topics and across systems. It is the perfect resource for bridging the gap between A-Level and university, studying a new topic, revising for exams, or refreshing knowledge while on placement. Key features: * Fully cross-referenced to Medicine at a Glance: together they cover the core concepts of an entire medical degree * Highlights key points and their clinical relevance for quick revision and retention of what s most important * Brings together all the scientific content on a medical course in one easy-to-read, highly-illustrated title * Accompanied by a companion website at ataglanceseries.com/medicalsciences featuring interactive multiple-choice questions and key points for revision Medical Sciences at a Glance provides the vital scientific grounding needed to succeed at medical school.

Practicing Patient Safety in Psychiatry covers all problematic aspects of care delivery in an easy-to-read format. Both portable and practical, this easily referenced guide book is designed for psychiatric residents and clinicals looking to improve their understanding of critical care. Featuring a wide variety of case-studiy examples and take-home points, this book is an essential introduction of patient safety for practitioners looking to deliver the highest quality of care in both inpatient and outpatient environments. Dr. Geetha Jayaram has been the Physician Advisor for the department of Psychiatry at Johns Hopkins Hospital for 21 years, and the Chair Of the International Patient Safety committee for the American Psychiatric Association. Dr. Jayaram is an outstanding clinician who has thought patient safety to residents and faculty for two dedcades. She is a pioneer in the field of psychiatric pateint safety, and has been invited to teach safety both nationally and internationally for many years.

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.

Maximise your exam success with this unique revision guide on core clinical specialties. The fourth edition of Oxford Assess and Progress: Clinical Specialties features over 400 Single Best Answer questions that are mapped to the medical school curricula. Packed with questions written by experienced doctors in each specialty, and rooted in real-life clinical encounters, this revision tool is an authoritative guide for students. Further reading resources and cross-references to the Oxford Handbook of Clinical Specialties have been fully updated to expand your revision further on topics you find challenging.

Textbook of Lifestyle Medicine The Textbook of Lifestyle Medicine provides foundational knowledge essential to students and scientists across various disciplines to better understand this new area of research and practice. Incorporating the latest evidence-based research on the relationships between lifestyle factors and disease, this unique book discusses the practical tools necessary to address growing public health crises such as obesity, cancer, diabetes, and cardiovascular disease using a holistic approach to physical, mental, and spiritual wellness. The book offers comprehensive and up-to-date coverage of how lifestyle medicine professionals can prevent and mitigate 'Lifestyle Diseases'. Clear and accessible chapters explore modifiable lifestyle factors that positively affect health, nutrition, exercise, sleep, stress control, and social support, and highlight the negative impact of smoking, alcohol abuse, and other unhealthy lifestyles. Topics include sleep physiology, the genetic background and development of noncommunicable diseases (NCDs), the characteristics and principles of healthy lifestyle, the clinical significance of physical activity, and the mechanisms connecting social interaction and health implications. This important resource: Discusses the global burden and risk factors of the modern disease epidemic Covers a variety of nutritional approaches including the Mediterranean Diet and the Dietary Approaches to Stop Hypertension (DASH) diet Features in-depth coverage of the Mediterranean Lifestyle, a holistic approach to health and wellness Includes a clinical practice section and appendices on preventive medicine and public health tools and recommendations Contains key points, take-home messages, self-assessment questions, color artwork and numerous references, citations, internet links, and further reading suggestions Written by two world experts in this growing field, the Textbook of Lifestyle Medicine is a must-have volume for students and practitioners in nutrition, exercise physiology, psychology, addiction therapy, sleep therapy, as well as physicians, nurses, and other health professionals wanting to expand their knowledge and practice.

Patients with a range of medical conditions undergo surgeries of varying levels of risk, and the evolving field of consult medicine aims to address their needs, whether pre- or post-surgery. This new edition of The Perioperative Medicine Consult Handbook provides useful information, advice, and guidelines based on a combination of clinical experience and evidence-based medicine. It covers topics in many major clinical areas (anesthesiology, cardiology, pulmonology, gastroenterology, rheumatology, endocrinology, and many others) and puts critical surgery information at a consult physician's fingertips. New to this edition are chapters on thyroid disease, restrictive lung disease, sickle cell disease, inflammatory bowel disease, nutrition, and perioperative care of elderly patients. The entire volume has been streamlined for a more precise presentation of essential perioperative management guidelines. Originally created by the Medicine Consult Service team at the University of Washington Medical Center, and now fully updated into a comprehensive second edition, this quick reference is sure to be indispensable for residents and consult physicians alike.

Mapping BRICS Media is the first comprehensive and comparative study of the emerging media landscape in the world's most dynamic and fastest growing markets. This pioneering collection focuses on one of the key topics in contemporary international relations - the emergence of BRICS (Brazil, Russia, India, China and South Africa) - a grouping that includes some of the world's largest populations and fastest growing economies. The volume brings together leading scholars, mainly from the BRICS nations, to examine how the emergence of the BRICS media will impact on global media and communication. Contextualizing the rise of the BRICS nations within the broader shifts in global power relations, the chapters investigate the unprecedented growth of the BRICS media within a 'multi-polar' world, evaluating the media landscapes in the individual BRICS countries, their histories, and their journalism practices, as well as analyzing emerging inter-BRICS media relationships. Accessible and comprehensive, the book provides a critical guide to the complex debates about the impact of the 'rise of the rest' on the media globe and how far this poses a challenge to the Western-dominated world order and its media systems.

Artificial Intelligence for Improved Patient Outcomes provides new, relevant, and practical information on what AI can do in healthcare and how to assess whether AI is improving health outcomes. With clear insights and a balanced approach, this innovative book offers a one-stop guide on how to design and lead pragmatic real-world AI studies that yield rigorous scientific evidence-all in a manner that is safe and ethical. Daniel Byrne, Director of Artificial Intelligence Research at AVAIL (the Advanced Vanderbilt Artificial Intelligence Laboratory) and author of landmark pragmatic studies published in leading medical journals, shares four decades of experience as a biostatistician and AI researcher. Building on his first book, Publishing Your Medical Research, the author gives the reader the competitive advantage in creating reproducible AI research that will be accepted in prestigious high-impact medical journals. Provides easy-to-understand explanations of the key concepts in using and evaluating AI in medicine. Offers practical, actionable guidance on the mechanics and implementation of AI applications in medicine. Shares career guidance on a successful future in AI in medicine. Teaches the skills to evaluate AI tools and avoid being misled by the hype. For a wide audience of healthcare professionals impacted by Artificial Intelligence in medicine, including physician-scientists, AI developers, entrepreneurs, and healthcare leaders who need to evaluate AI applications designed to improve safety, quality, and value for their institutions. Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

The second edition of this concise and practical guide describes infections in geographical areas and provides information on disease risk, concomitant infections (such as co-prevalence of HIV and tuberculosis) and emerging bacterial, viral and parasitic infections in a given geographical area of the world. * Geographic approach means that it's the only book to guide the health care worker towards a diagnosis based on the location of symptoms and travel history by encouraging the question where have you been? * New content covering MERS, Ebola, Zika, and infections transmitted during air and maritime travel * Covers the major infectious disease outbreaks framed in their geographic setting such as H7N9 bird flu influenza, H1N1, Ebola, and Zika * Outstanding international editor team with vast experience on various international infectious disease and as journal editors and key leaders in infection surveillance

Read with two objectives: first, to acquaint yourself with the current knowledge of a subject and the steps by which it has been reached; and secondly, and more important, read to understand and analyze your cases. William Osler, The Student Life What follows is a collection of cases-or more aptly, the stories of our patients and friends who have been seen at The Ohio State University Hospitals where our faculty have provided their care and about whom this volume is written. Today many fear that our patients are being moved from center stage while we are being distracted by the technology of medicine. This volume was written with patients in mind. The idea is that the most intriguing questions and the most rewarding answers begin and end at the bedside. This is a story of our patients, told by expert clinicians and spiced with commentary along the way. This volume in no way at tempts to be comprehensive. Instead, it is like the practice of medicine, scattered, somewhat disjointed, while at the same time intensely personal and focused upon whatever problem the patient brings to us. The discussions are not so much about disease entities as they are about patients with problem." The two are uniquely dif ferent. For instance, when the physician suspects hepatitis, not every imaginable cause can be actively investigated. Instead, tests and procedures are discriminate ly chosen, a part of medicine that is still more art than science."

It is a pleasure to present the book, Evaluation and Treatment of Obesity, for reference and textbook use. The text is an outgrowth of the Obesity Weight Control Track of the 1982 La Crosse Health and Sports Science Symposium, sponsored annually by the La Crosse Exercise Program, Uni versity of Wisconsin-La Crosse. With versatile faculty, topics, and attend ing professionals, the Obesity-Weight Control Track stimulated an effort to produce interdisciplinary resources on obesity. Out of this effort, three books have been compiled and edited. This book, Evaluation and Treatment of Obesity, introduces an interdis ciplinary, practical approach to obesity management. The other two books, Nutrition and Exercise in Obesity Management and Behavioral Management of Obesity, expand on the basic theories introduced in this book, providing in-depth information of value to the practicing profes sional. These three books apply the latest information from the fields of medicine, nutrition, exercise, and psychology to the problem of obesity. The information is intended to guide health professionals in the inter disciplinary management of obesity. In 1983 the Obesity-Weight Control Track focused on controversial issues of theoretical and practical concern. The speakers from this track contributed their expertise to the compilation of two additional books. Thus, Trends and Controversies in Obesity Research and Innovation in Obesity Program Development will complete the series. Consider the five volumes a consolidated, comprehensive reference related to the growing, interdisciplinary field of weight control."

Generalized anxiety disorder (GAD) was first characterized by Freud as part of anxiety neurosis and became part of the diagnostic nomenclature in 1980. GAD is a chronic condition, which affects between 6% -10% in the general population. It is associated with significant functional impairment and increased risk of adverse health outcomes, including cardiovascular disease. It is also frequently found in conjunction with other psychiatric conditions, including mood and other anxiety disorders, and alcohol and substance abuse/dependence. Somatic symptoms are common in GAD, and patients diagnosed with GAD visit primary care physicians twice as often as patients with similar medical and socioeconomic backgrounds. Part of the Oxford Psychiatry Library series, this pocketbook provides a user-friendly overview of the characterization, diagnosis, evaluation and treatment of GAD in addition to differential diagnoses, pathogenesis, course and clinical co-morbidity associated with this disorder. Each chapter begins with a series of key points.

The key resource you need to prepare for the American Board of Internal Medicine (ABIM) Certification and Maintenance of Certification examinations. Now in its twelfth edition, Mayo Clinic Internal Medicine Board Review builds on years of knowledge, refinement, and expertise from Mayo Clinic's Department of Medicine and the successful certification process, providing the latest information you need. Now including Physician Well-Being and Hospital Internal Medicine, over 80 chapters help you confidently sit for the boards. Not preparing to certify or recertify? This all-inclusive reader-friendly volume is the perfect companion for anyone seeking to provide state-of-the-art care to patients, to serve as a core textbook for internal medicine residency training, or for students preparing for USMLE Step 3 examinations.

Part of the highly popular and respected Pocket Notebook series,Pocket Primary Care, 3rd Edition, puts answers to common diagnostic questions in the outpatient setting at your fingertips in seconds. Dr. Curtis R. Chong and his team of expert contributors provide current evidence-based practices, accepted best practices, and real-world guidance on all major subspecialties, including appropriate workups and when to refer. This practical, high-yield reference mirrors the thought process of primary care clinicians in day-to-day practice, all in an easy-to-use, loose-leaf format that's ideal for physicians, students, residents, nurses, and PAs-anyone who sees patients in today's busy ambulatory settings. Contains fully updated information throughout, including the latest clinical guidelines and new therapeutic recommendations. Features bulleted lists, tables, diagrams, and algorithms that provide focused information on everything you need to know in order to make an accurate diagnosis and develop a treatment plan. Includes a new chapter on COVID-19. Covers all diseases and conditions commonly seen in the clinic or ambulatory setting, including topics such as routine screenings, health literacy, disease screening, psychiatry, women's health, men's health, and geriatrics. Provides references to landmark papers that help residents and students confidently answer questions during rounds.