Clinical reasoning lies at the core of health care practice and education. Clinical Reasoning in the Health Professions, therefore, occupies a central place in the education of health professionals, the enhancement of professional decision making of individuals and groups of practitioners with their clients, and research into optimal practice reasoning. Key themes presented: Clinical reasoning as a composite of encultured capabilities Clinical reasoning embedded within situated practice including the wider socio-economic and political contexts, the practitioner's and the client's contexts, and shared goals such as promoting health communities The importance of narratives, language and culture in clinical decision making Changing reasoning practices linked to increasing autonomy of practitioners working without the requirement of medical referrals Clinical reasoning as an increasingly team-based practice, including shared decision making with clients The need for sound strategies and tools to facilitate the expanding collaborations in health care across disciplines and with clients and carers Advanced education approaches promoting expansion and enhancement of reasoning strategies The importance of building good practices for learning clinical reasoning into curricula and into students' own practice development approaches Strengthening links between orthodox and complementary medicine reasoning practices New to this edition: All chapters updated and 20 new chapters added Concrete examples, cases and vignettes were added to bring discussions to life for the reader Reflection points strategically placed to assist readers to extend their insights and build learning from their own practical experiences and theoretical knowledge Devices of particular value to reflective practitioners and educators. This is a book for teachers and learners, practitioners, practice leaders, researchers and curriculum managers. Indeed, it is a valuable resource for educators seeking to ground their teaching practices in educational theory, sound knowledge of clinical reasoning and practice-based evidence, and researchers seeking to expand their research horizons. All chapters updated and 20 new chapters added Concrete examples, cases and vignettes were added to bring discussions to life for the reader Reflection points strategically placed to assist readers to extend their insights and build learning from their own practical experiences and theoretical knowledge Devices of particular value to reflective practitioners and educators.

Mit diesem UEbungsbuch koennen Sie als internationale AErztin oder Arzt Ihre Deutschkenntnisse gezielt und effektiv vertiefen - in der Gruppe oder alleine. Es enthalt zahlreiche und abwechslungsreiche UEbungen fur die Vorbereitung auf die Fachsprachprufung mit folgenden Schwerpunkten: UEben von Anamnesegesprachen - Training von Patientenvorstellungen - Aufbau von Grammatik und Wortschatz fur die Dokumentation - Lese- und Textverstandnis - Schriftlicher Ausdruck fur den Arztbrief. Entwickelt von Dozentinnen und Dozenten der Charite International Academy. Plus: Zugang zu Deutschkurs-Medizin.de mit Vokabeltrainer und Audiodateien. So erhalten Sie mehr Sicherheit im Umgang in der deutschen Sprache und mit medizinischen Fachbegriffen beim Sprechen und Schreiben. Die ideale Vorbereitung auf den Fachsprachtest und auf Ihre Aufgabe im Krankenhaus oder der Arztpraxis.Neu in der 2. Auflage: Weitere Fallbeispiele und noch mehr UEbungen.

Angesichts des harten Wettbewerbs wird in Zukunft voraussichtlich ein Drittel aller Krankenhauser schlieen mussen. Allein verstarkte marktwirtschaftliche Optimierung - inklusive des dazugehorigen Marketings - sichert Krankenhausern das Uberleben. Das Buch gibt Antworten auf Fragen wie: Welche Bedurfnisse haben die verschiedenen Anspruchsgruppen? Welche zusatzlichen Leistungen konnen angeboten werden? Leser finden das Handwerkszeug fur die Realisierung einer gelungenen Marktprasenz - von der Analyse, uber die Konzeption bis zur Umsetzung.

Dieses essential gibt einen Kurzuberblick uber psychosoziale Aspekte von Patienten mit Hirntumoren. Die Arbeit mit dieser besonderen Patientengruppe erfordert spezifische Kenntnisse in den Bereichen Neuropsychologie, Psychoonkologie und Psychotherapie, die praxisnah vermittelt werden. Patienten mit intrakraniellen Tumoren zahlen zu den am starksten belasteten Patientengruppen uberhaupt. Sie sind nicht nur von allen Belastungsfaktoren onkologischer Erkrankungen betroffen, zu welchen zum Beispiel die langwierige und nebenwirkungsreiche medizinische Therapie oder die oft verringerte Lebenserwartung zahlen, sondern auch von allen Belastungsfaktoren neurologischer Erkrankungen, worunter auch neuropsychologische Veranderungen wie kognitive Defizite, eine verminderte Kommunikationsfahigkeit und organisch bedingte Persoenlichkeitsveranderungen fallen.

To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system.

Chapters in this book deal specifically with cell fate determination, cell migration and disorders of cell migration; current concepts and new ideas about cortical arealisation, and disorders which can arise from incorrect arealisation; genes implicated in the development of cortical connectivity and related pathologies such as schizophrenia and synaesthesia; and susceptibility genes for cognitive disorders such as schizophrenia, autism, dyslexia, and attention deficit disorder.

This issue of Medical Clinics of North America, guest edited by Paul S. Pottinger and Christopher A. Sanford, is devoted to Travel and Adventure Medicine. Articles in this issue include: Immunizations; Malaria; Personal Protection Measures; Traveler's Diarrhea; Urban Medicine and Trauma; Care of the Healthcare Provider; Evaluation of the Ill Returned Traveler; The Ethics of Medical Volunteerism; High-Altitude Medicine; Dive Medicine; Wilderness Medicine, Including First Aid & Hypo/Hyperthermia; The Medical Kit; Adventure Sports: Spelunking, water exposures; and Resources for the Provider and Opportunities in Further Training in Travel and Adventure Medicine.

The science and applied approaches of enzyme inhibition in drug discovery and development

Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, "Enzyme Inhibition in Drug Discovery and Development" examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development.

With chapters written by over fifty leading experts in their fields, "Enzyme Inhibition in Drug Discovery and Development" fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the "good" inhibitions--desirable pharmacological effects--and "bad" inhibitions--drug-drug interactions and toxicity. The book discusses:

The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment

The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug-drug interactions

The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway

Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.

This issue of Medical Clinics of North America, Guest Edited by Douglas S. Paauw, MD is devoted to Comprehensive Care of the Patient with Chronic Illness. Dr. Paauw has assembled a group of expert authors to review the following topics: Primary Care of the Homeless Patient; Primary Care of the Patient with Chronic Liver Disease; Primary Care of the Transplant Patient; Primary Care of the Patient with CRI; Primary Care of the Patient with Alcoholism; Primary Care of the Childhood Cancer Survivor; Primary Care of the Immigrant Patient; Primary Care of the HIV Patient; Primary Care of the Patient with Chronic Lung Disease; Primary Care of the Patient with Sarcoid; and Primary Care of the Patient with Inflammatory Bowel Disease.

This book gathers together the collected wisdom of an experienced group of practitioners from the world of blood conservation including surgeons, anaesthetists, haematologists, transfusion specialists, microbiologists, and legal advisors. Topics included are: an historical overview, transfusion-transmitted diseases, changing demographics and the projected impact on blood supplies, who needs transfusion, practicalities and tips - how to do it, the laboratory perspective, haemodilution, intra-operative cell salvage, surgical methods to minimise blood loss, anaesthetic methods to minimise blood loss, pharmacological methods to minimise blood loss, postoperative salvage, postoperative haemoglobin, cancer patients, patient consent and refusal, trauma management, patient ID and documentation, audit/clinical governance, the role of the Hospital Transfusion Team, education, national reports including European Directives, further information. Additional chapters will include pre-operative blood management, near-patient testing, the incidence and relevance of pre-operative anaemia, anaemia management in obstetrics, pre-operative anaemia in orthopaedics, haemostatic sealants, the effect of transfusion in cardiovascular surgery, transfusion alternatives.

This textbook provides practical tips on the conduct of aortic surgery, from the aortic valve to the iliac arteries. It is organized as a series of Plates, each with a key central illustration, followed by bullet items of accompanying explanatory text. The accompanying text concentrates on specific, critical "do's and don'ts" that promote and enhance patient safety. Chapters include dozens of color illustrations by one of the nation's premier medical illustrators, along with selected classic "pen and ink" line drawings. Each central illustration is accompanied by additional secondary figures interspersed at intervals within the accompanying text. Each "practical tip" has an accompanying short (15-30 second) video demonstrating vividly the specific didactic point being made in each Plate. Chapters provide Q&A sections, to promote an interactive feel and experience. The textbook shares practical, potentially life-saving tips-gleaned from over three decades of experience in thousands of aortic operations-regarding virtually every standard operation that arises in aortic surgery. Practical Tips in Aortic Surgery will be an essential resource for surgeons and trainees at all levels of experience: residents and fellows, surgical physician assistants, surgical nurses and technicians, and medical students. The book directly targets two surgical specialties: Cardiac Surgery and Vascular Surgery

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients- updated and in full color A Doody's Core Title for 2011! 5 STAR DOODY'S REVIEW! "The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers....This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome."--Doody's Review Service "This invaluable up-to-date reference is a must have guide especiallyin non-tertiary care centers where the various experts may not be readily available tofurther guide the family and plan the rest of the antepartum, peripartum and postpartum care."--Center for Advanced Fetal Care Newsletter Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis-from prenatal management to long-term outcome-for an affected child. Here, you'll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality-and present them with a coordinated therapeutic plan. Features NEW! Full-color design NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology NEW! Key Points open each chapter, providing rapid review of a particular condition Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research

Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.

Holistic physical therapist, human MRI, and master healer Vivian S. De Guzman, PT has guided thousands toward honing their intuitive gifts for decades. Now, she writes Awaken Your Medical Intuition to help healthcare professionals harness their power so that they can make the biggest impact possible with their life and soul's purpose. Within Awaken Your Medical Intuition, Vivian shares with healthcare professionals: The truth about why they keep on avoiding their gifts as a medical intuitive The reason most doctors, healthcare professionals, empaths, and healers fail in their business The difference between people who are ready to acknowledge their medical intuitive gifts and those who are not Factors contributing to their energetic imbalances and health problems. How to align all of them to bring wealth, health, and great relationships! Practical, simple, and highly-effective tools to open and enhance their intuitive skills

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the first of two volumes covering protein kinase inhibitors in research and medicine, and includes chapters on such topics as fragment-based screening, broad kinome profiling of kinase inhibitors, and designing drug-resistant kinase alleles.
First of two volumes focusing on protein kinase inhibitors in research and medicinePart of the Methods in Enzymology serial with authors who are experts in their disciplines

This issue of the Atlas of the Oral and Maxillofacial Surgery Clinics of North America serves as an aid to identification of 70 of the more important head and neck syndromes, and organized using the same nosology as in the landmark text of Robert Gorlin. As such, it should be useful to a varied audience, including not only the oral and maxillofacial surgeon but also the oral pathologist, the practitioner of oral medicine, and members of the craniofacial team--the orthodontist, pediatric dentist, speech and language specialist, geneticist, plastic surgeon, ENT specialist, pediatrician, nurse coordinator, and others. Areas covered include: Craniosynostosis Syndromes; Syndromes Affecting Bone; Metabolic and Autoimmune Syndromes; Syndromes Affecting Skin and Mucosa; Hamartoneoplastic Syndromes; Branchial Arch Syndromes; Clefting Syndromes; Syndromes Affecting the Central Nervous System; Chromosomal Syndromes; Syndromes with Unusual Facies; and Syndromes with Unusual Dental Findings or Gingival Components.

Blood is life, its complex composition is finely attuned to our vital needs and functions. Blood can also signify death, while 'bloody' is a curse. Arising from the 2021 Darwin College Lectures, this volume invites leading thinkers on the subject to explore the many meanings of blood across a diverse range of disciplines. Through the eyes of artist Marc Quinn, the paradoxical nature of blood plays with the notion of self. Through those of geneticist Walter Bodmer, it becomes a scientific reality: bloodlines and diaspora capture our notions of community. The transfer of blood between bodies, as Rose George relates, can save lives, or as we learn from Claire Roddie can cure cancer. Tim Pedley and Stuart Egginton explore the extraordinary complexity of blood as a critical biological fluid. Sarah Read examines the intimate connection between blood and womanhood, as Carol Senf does in her consideration of Bram Stoker's novel Dracula.

This issue of the Medical Clinics of North America, edited by Douglas Paauw, is devoted to Common Symptoms in the Ambulatory Setting.? Articles in this issue include: Evaluation and treatment of chronic cough; Evaluation and treatment of lower back pain; Lower extremity symptoms; Common dermatologic problems; Evaluation and treatment of shoulder pain; Headache; Evaluation and treatment of colonic symptoms; Dyspepsia; Insomnia; Dizziness; Fatigue; Common anal problems; Involuntary Weight Loss; Evaluation and treatment of neck pain; and Multiple unexplained symptoms.

To ensure the best outcomes, cardiologist must have a deep understanding of the design, manufacturing, and malfunctions of implantable devices. This issue of Cardiac Electrophysiology thoroughly examines implantable devices, providing the most reliable and updated information. Topics include MRI conditionally safe pacemakers, complications in lead extraction, troubleshooting malfunctioning pacemakers and ICDs.

This issue of Medical Clinics will focus on the common foot and ankle problems that internal medicine doctors often face in the outpatient setting. The articles in this issue will review best practices for managing and treating patients who present with such common injuries hammertoes, ankle sprains, plantar fasciitis, and achilles tendon strains.

Novartis Foundation Symposium 289

"Growth factors and psychiatric disorders"

Chair: Moses V. Chao

Psychiatric disorders such as depression, bipolar disease and schizophrenia are debilitating illnesses that are influenced by many genetic and environmental factors. While little is known about the neural circuits that underlie such disorders, the convergence of psychiatric, genetic and basic neuroscience research is providing new and exciting insights.

In recent years genetic studies have identified several growth factors as susceptibility genes for depression, schizophrenia, and learning and memory. This suggests that psychiatric disorders may be influenced by a small number of genes with multiple actions. These genes will provide clues to the biochemical mechanisms and pathways that underlie these complex disorders.

This is the first book to undertake a comprehensive investigation of this research. International leading experts are brought together to discuss the latest findings and look at future directions.

Topics addressed include Neuroplasticity and neurotrophic factors. Mechanisms of intracellular trafficking of growth factors. BDNF gene variants in affective disorders. Trophic factors and cognitive functions. Neurotrophins and depression. Schizophrenia genes and neuropathology. Pharmacological treatments of schizophrenia.

"Growth factors and psychiatric disorders" will be of particular interest to psychiatrists, neurologists and geneticists, as well as cell and molecular biologists, and neuroscientists.

Evidence synthesis is the evaluation or analysis of research evidence and opinion on a specific topic to aid in decision-making in health care. Although the science of evidence synthesis has developed most rapidly in relation to the meta-analysis of numerical data linked to theories of cause and effect, the further development of theoretical understandings and propositions of the nature of evidence, its role in health care delivery, and the facilitation of improved global health have increased rapidly since 2000. The articles appearing in this issue examine the role of evidence synthesis in nursing and health care and are written by expert translational scientists from across the world. Three introductory articles overview evidence synthesis and its role in evidence-based health care; methods, issues, and trends in the systematic review of health care evidence; and the development of a robust evidence base for nursing. Subsequent articles explore the impact of systematic reviews on policy and practice in a variety of settings, including perioperative care, pediatrics, rehabilitation and long-term/continuing care, mental health, and public health. The final articles discuss the impact of evidence on health policy and practice and the complexities of translating evidence into policy and practice. These articles show the importance of synthesizing evidence and translating policy and practice into action in our quest to improve health care and health outcomes.