In Vivo Models of Inflammation (Volume 1 and Volume 2) provides the biomedical researcher in both the pharmaceutical industry and academia with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first edition by describing and updating the standard models that are most utilized for specific disease areas. In addition, new models are included exploring emerging areas of inflammation research. The format is designed with the laboratory in mind: Both volumes provide detailed descriptions of the methodologies and uses of the most significant models. This includes current information regarding agents that demonstrate efficacy, those that do not and those that can be used as standard controls. The focus remains on those models that serve as pre-clinical correlates to human disease as well as those that represent components of the inflammatory response. Pioneering ideas and provocative comments about future directions are meant to challenge the status quo and stimulate new thinking. Therefore, new approaches to the development of future models in selected therapeutic areas have been highlighted. The focus on novel technologies that are vital for innovative in vivo research has been expanded to include chapters on the use of transgenic and gene transfer technologies, nanotechnology, and stem cells. This up-to-date reference manual helps to select the best animal model for a specific question. At the same time, this set of books continues to acknowledge the solemn responsibility in vivo research carries with it and extends the coverage of animal respect and welfare when used in experimental settings. Chapters describing current regulations in the United States, United Kingdom, and Japan address these concerns. Thus, the ultimate aim of this set of books is to provide current best practices for obtaining the maximum informat

This groundbreaking book unleashes a brilliant new plan for permanently curing heartburn by relieving the root cause of the problem: low stomach acid. The fact is that heartburn is caused by too little stomach acid -- not too much, as many doctors profess. As explained in this book, the current practice of reducing stomach acid may be a temporary fix, but this fix comes at a cost to our long-term health that is being ignored by the pharmaceutical companies, the FDA, and the thousands of physicians that prescribe anti-acid drugs like Prilosec, Tagamet, Zantac, Pepcid, and others.

The new edition of this best-selling title from the popular 100 cases series explores common scenarios that will be encountered by the medical student and junior doctor when working in the community setting, and which are likely to feature in qualifying examinations. The book covers a comprehensive range of presentations from tiredness to tremor. Comprehensive answers highlight key take home points from each case and provide practical advice on how to deal with the challenges that occur in general practice at all levels.

"MRCP Part 1 Self-Assessment" is the perfect revision aid. Drawn from the highly successful Medical Masterclass material from the Royal College of Physicians of London, this concise volume is specifically designed to cover the topics and format found in the Membership to the Royal College of Physicians (MRCP) Part 1 examination. The large scale, lavishly illustrated, full-colour format makes it easy to comprehend complex topics. With contributions from an extensive list of prestigious and authoritative professionals, the questions cover all areas of assessment, including the scientific background the medicine, general clinical skills, acute medicine and a range of specialties. It is ideal for examination MRCP candidates, doctors preparing for the European Diploma in internal medicine and junior doctors wanting to revise their knowledge and skills.'This collection of self-assessment questions and explanatory answers has been drawn from Medical Masterclass, which is produced and published by the Royal College of Physicians of London. The questions have been specifically written to help doctors in their first few years of training to test and revise their medical knowledge and skills; and in particular to pass postgraduate examinations, such as the MRCP(UK)' - John D Firth, in the Introduction.

Praise for
Improving Healthcare Through Advocacy
A Guide for the Health and Helping Professions

"Bruce Jansson's thoughtful and innovative book will appeal to students in social work, nursing, and public health as well as those working in the health field of practice. The case examples are extraordinary, and Jansson provides the ideas, context, and theoretical base for readers to acquire the skills of advocacy in healthcare. This is by far the best advocacy book I have seen."
--Gary Rosenberg,
PhD Director, Division of Social Work and Behavioral Science
Mount Sinai School of Medicine

""Improving Healthcare Through Advocacy" is a terrific description of opportunities for advocacy intervention and provides the skill sets necessary for effective advocacy. A needed book."
--Laura Weil, LCSW
Director, Health Advocacy Program
Sarah Lawrence College

""Improving Healthcare Through Advocacy" is an invaluable resource for practitioners working in the healthcare field as well as for students. It very thoroughly covers healthcare advocacy issues, contains real-world case examples, and provides a clear, step-by-step framework for practicing advocacy."
--Kimberly Campbell, ACSW, LCSW
Lecturer, Department of Social Work
Ball State University

An important resource for all who strive for the best in healthcare treatment for their patients, themselves, and the nation

Bestselling author and award-winning researcher Bruce S. Jansson uses an intervention framework to illustrate how everyone in the healthcare system can advocate effectively, not just for better healthcare delivery to individual clients but for the necessary policy change that will deliver long- term solutions to our nation's healthcare crisis as well.

"Improving Healthcare Through Advocacy" provides professionals with:

Tools to move from traditional services to case advocacy and policy advocacy tasks

Over 100 case studies from the perspective of patients, healthcare providers, and others who relate the experiences they have encountered in the healthcare system and share the wisdom they have learned

Practical tips on how to provide effective advocacy and bring about positive and long-term change in this complex environment

Etwa 30 % aller Menschen, die eine Arztpraxis aufsuchen, leiden an seelisch bedingten Erkrankungen. Fur Arzte ist es daher notwendig diese Patienten angemessen zu erkennen, mit ihnen umgehen, sie behandeln oder an Fachvertreter uberweisen zu konnen. Die Grundlagen der psychosomatischen Medizin zu beherrschen ist somit fur Studierende, Arzte aller Fachdisziplinen wie auch fur psychologische Psychotherapeuten unumganglich. Im Klussmann" werden die wichtigsten Krankheitsbilder aller klinischen Fachgebiete aus psychosomatischer Sicht behandelt. Dabei erleichtern Einleitungen und Definitionen den Einstieg in die Materie, zahlreiche Fallbeispiele sorgen fur Anschaulichkeit und stellen den Bezug zur Praxis her. Umfangreiche Hinweise zu weiterfuhrender Literatur, ein Glossar und ein Verzeichnis psychotherapeutisch/psychosomatischer Einrichtungen erhohen den Wert dieses Lehrbuchs als Nachschlagewerk."

This book provides the reader with a comprehensive study of the cervical spine in children and young adults. Written by Dr. Leonard Swischuk, a distinguished leader in the field of pediatric radiology, the book presents normal anatomy and embryology, especially as it is relevant to trauma, normal variations and congenital anomalies. The second part of the book deals with trauma, focusing on a systematic accounting of the various injuries encountered and each explained in terms of the mechanism of the injury. Emphasis is placed on plain films since this is the most important study for the cervical spine. CT and MRI will be used to amplify findings. An indispensable resource for anyone dealing with the cervical spine.

A growing number of adolescents do not have a supportive and trusting relationship with an adult in a birth, foster, adoptive, or chosen family. Through a variety of circumstances, they are literally or functionally 'alone'. Yet like all adolescents they need routine and sometimes specialized health care. This book is a collection of essays, case studies, and guidelines that describe the demography, philosophical, medical, legal, and developmental framework in which these youth and health care staff confront medical decision making. The authors address questions of consent, confidentiality, access to care, and the right to refuse or demand care. Throughout the emphasis is on the real-world experience of adolescents as they struggle to overcome the challenges of being alone. Professionals who work with these adolescents cannot replace their absent or disinterested families but can fulfill the critical role of trusted adult advisor.

A growing number of adolescents do not have a supportive and trusting relationship with an adult in a birth, foster, adoptive, or chosen family. Yet like all adolescents they need routine and sometimes specialized health care. This book is a collection of essays, case studies, and guidelines that describe the demographic, philosophical, medical, legal, and developmental framework in which these youth and health care staff confront medical decision making. The authors address questions of consent, confidentiality, access to care, and the right to refuse or demand care, emphasizing the real-world experience of adolescents as they struggle to overcome the challenges of being alone.

ABC of Clinical Resilience ABC of Clinical Resilience For the healthcare professional, clinical resilience is about reconnecting with those stirrings which first motivated us to spend a career in the service of others. It is about recovering and maintaining the joy of practice which nourishes and satisfies our curiosity about the uniqueness of every person in our care. Being a resilient practitioner is essential for our personal wellbeing and also for the safety of our patients, who depend on our ability to optimise our physical and cognitive performance. Yet many healthcare professionals report experiencing burnout. ABC of Clinical Resilience summarises current evidence on how cognitive performance and wellbeing of healthcare professionals are affected by the emotional context of providing care and the organisational culture of working environments. As well as considering impacts of individuals and teams, we also consider how resilience can be recovered for the benefit of everyone. Topics include: The emotional impact of working in healthcare Resilience and cognitive performance Practicing self-care The physiology of resilience Intelligent kindness Kindness in teams Resilience in practice Organisational kindness Teaching resilience Perfect for both novice and experienced healthcare professionals, including those working in mental health, ABC of Clinical Resilience will also earn a place in the libraries of professionals who treat healthcare workers and readers interested in the psychology and prevention of burnout, vicarious trauma, and moral injury. About the ABC series The ABC series has been designed to help you access information quickly and deliver the best patient care, and remains an essential reference tool for GPs, junior doctors, medical students and healthcare professionals. Now offering over 80 titles, this extensive series provides you with a quick and dependable reference on a range of topics in all the major specialties. The ABC series is the essential and dependable source of up-to-date information for all practitioners and students in primary healthcare. To receive automatic updates on books and journals in your specialty, join our email list. Sign up today at www.wiley.com/email

Clinical CT: Techniques and Practice aims to give radiographers working in CT on a regular basis an extended knowledge of CT protocols and how they should be adapted to optimise image quality. It uses relevant clinical examples to demonstrate the advantages of the suggested techniques, which may not yet be in use in all hospitals. It covers all but the most rare of pathologies and will therefore also serve as a useful single reference for the busy radiographer.

Make the most of every patient encounter - from the clinical interview and history to the physical exam, both in-office and bedside. This discreet quick reference by Ilene L. Rosenberg, MD, FCCP, Todd Cassese, MD, FACP, and Dennis Barbon, RN, helps you achieve consistent and comprehensive results when collecting data and determining your next steps. Carry this thin, fully illustrated checklist in your white coat pocket for the fastest, most efficient way to access essential information you need to know and remember every day. Point-of-care reminders in the office or on the wards - immediately see what to ask, what exams to perform, what to look for, and more. Fully illustrated memory triggers throughout. Each topic is contained on one page or two facing pages for at-a-glance reference. An excellent everyday pocket reference as well as a handy review for Step 2 CS (Clinical Skills) and OSCEs (Objective Structured Clinical Exams). Written by educators who know first-hand what needs to be reviewed and remembered during the clinical patient encounter.

Point of care ultrasound is a critical tool required for assessing all patients, providing rapid answers to clinical questions and facilitating high quality care for patients. This essential guide caters for all generalist clinicians beginning their ultrasound journey and extends to more advanced assessments for those with established ultrasound experience wishing to advance their knowledge and skills. It covers a wide range of ultrasound topics from echocardiography, thoracic and COVID-19 to emerging areas such as palliative care, hospital at home and remote and austere medicine. An extensive collection of colour images, videos and examples of clinical applications will inspire readers to acquire the skills of point of care ultrasound quickly, safely and systematically. The printed code on the inside of the cover provides access to an online version on Cambridge Core. An essential aid for acute clinicians, paramedics, general practitioners as well as remote medical providers, medical educators and students.

The aim of this book is to provide the target audience, specifically students of Medicine, Biology, Systems Biology and Bioinformatics, as well as experienced researchers in research fields relevant to metabolic syndrome (MetS) with an overview of the challenges and opportunities in systems biology and how it can be used to tackle MetS. In particular, the aims are: (1) to provide an introduction to the key biological processes involved in the pathophysiology of MetS; (2) through the use of specific examples, provide an introduction to the latest technologies that use a systems biology approach to study MetS; and (3) to give an overview of the mathematical modeling approaches for studying MetS.

The clearly written chapters by leading experts in the field provides detailed descriptions crucial for the unique position of this book and its focus on the application of systems biology to tackle specific pathophysiologically relevant aspects of MetS and provides a valuable practical guide to this research community.

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This book offers an overview of the complex interplay between hormonal activation and individual and environmental influences on health and disease in women. The book provides useful information and background material important for treating problems related to the reproductive cycle, eating disorders, drug treatment of women, and clinical and treatment issues in coronary artery disease and breast cancer. This is a medically-oriented book written firstly for the practicing physician in primary care, psychiatry, internal medicine and gynecology/obstetrics. This book takes a much broader view than others on the market by combining consideration of both psychological and physical disorders affecting women and by discussing treatment issues.

The MRCP examination is constantly changing, reflecting the changing pressures on doctors in training. Whilst the MRCP PACES examination has evolved with the times, the core ethos of it, to act as a benchmark for sound clinical examination, logical diagnostic ability, common sense and most importantly, the development of compassionate and ethical physicians has remained unchanged.Whilst this exam has often struck fear into the hearts of junior doctors, we believe it is an assessment of progression during a physician's training that should be relished as an opportunity to demonstrate these ageless qualities that caring practitioners should possess.This book was born out of the philosophy that all doctors sitting their MRCP PACES already have the knowledge and skill to pass the exam, but just require guidance in the correct logical approach that the Royal College is looking for.The book has, therefore, quite unlike other MRCP PACES books, avoided any attempts at being a definitive text. Rather, it has focused on the key aspects that the authors believe are required to pass the examination, in particular focus on presentation style. Whilst medicine is indeed an ocean, the most commonly examined topics have been selected to reflect the likely scenarios a candidate will face - as the old adage goes - 'common things occur commonly'.In producing this book, extensive feedback was sought from candidates revising for the examination to reflect their needs. The layout therefore involves a methodical approach with a short introduction, similar to that presented in the exam, followed by clinical findings expected to be found. An example of presentation style has then been produced to allow the candidate to rehearse and practice this essential component of the exam.Doctors preparing for the exam have limited time due to busy work schedules. Therefore, summary books are key for candidates sitting the MRP PACES examination.Most PACES candidates fail the exam based on history and communication stations.Therefore, attention has been paid to:

With detailed contributions from 45 renowned international authorities, this Third Edition stands alone as the most comprehensive, contemporary view of the biology, physiology, and management of acute coronary syndromes (ACS)-offering 32 chapters that span the state-of-the science in the field and provide intriguing discussions on CRP and other disease markers, microcirculation, stem cell therapy, and the development of specialized centers for ACS treatment.

Selected as a Doody's Core Title for 2022! Designed for busy clinicians struggling to fit the critical issue of nutrition into their routine patient encounters, Nutrition in Clinical Practice translates the robust evidence base underlying nutrition in health and disease into actionable, evidence-based clinical guidance on a comprehensive array of nutrition topics. Authoritative, thoroughly referenced, and fully updated, the revised 4th edition covers the full scope of nutrition applications in clinical practice, spanning health promotion, risk factor modification, prevention, chronic disease management, and weight control - with a special emphasis on providing concisely summarized action steps within the clinical workflow. Edited by Dr. David L. Katz (a world-renowned expert in nutrition, preventive medicine, and lifestyle medicine) along with Drs. Kofi D. Essel, Rachel S.C. Friedman, Shivam Joshi, Joshua Levitt, and Ming-Chin Yeh, Nutrition in Clinical Practice is a must-have resource for practicing clinicians who want to provide well-informed, compassionate, and effective nutritional counseling to patients. Features short, easily digestible chapters with updated references. Includes comprehensive updates throughout, as well as a newly expanded section on Contemporary Topics in Nutrition. Covers key topics such as the ketogenic diet, intermittent fasting, ultraprocessed food, and strength of evidence assessment in nutrition. Provides data from recent nutritional studies, helpful nutrition data tables, clinically relevant formulas, and patient-specific meal planners. Addresses special topics such as pregnancy and lactation, pediatric nutrition, athletic performance and sports nutrition, health effects of specific foods, plant-based diets, and many more. Features expert contributions from authors with diverse expertise and practical experience in medical education, clinical practice, and preventive medicine. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,

This book provides a detailed overview of the function of the nervous system in fever and its role in antipyresis. The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. Sufficient information about bacterial pyrogens, 'endogenous' pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity is given to enable readers to follow the central nervous system's involvement. The book should enable graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying anti-pyretics and the central nervous system function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts. Finally, the author challenges some well-established dogmas in this area and sets an agenda for future research.

Critical care medicine is a relatively new specialty. Over the past few decades, we have seen an enormous growth in the number of inten sive care units (ICUs) worldwide. Medical students, residents, fellows, attending physicians, critical care nurses, pharmacists, respiratory ther apists, and other health-care providers (irrespective of their ultimate field of practice) will spend several months or years of their profes sional lives taking care of critically ill or severely injured patients. These clinicians must have special training, experience, and compe tence in managing complex problems in their patients. In addition, they must interpret the data obtained by many kinds of monitoring devices, and they must integrate this information with their knowl edge of the pathophysiology of disease. This handbook was written for every practitioner engaged in criti cal care medicine. We have attempted to present basic and generally accepted clinical information and some important formulas as well as laboratory values and tables that we feel will be useful to the practi tioner of critical care medicine. Chapter 1 provides an introduction to the ICU. Chapters 2 through 18 follow an outline format and are divided by organ system (i. e. , neurologic disorders, cardiovascular dis orders), as well as special topics (i. e. , environmental disorders, trauma, toxicology). In addition, many of these chapters review some useful facts and formulas systematically. Finally, Chapters 19 and 20 supply lists of pharmacologic agents and dosages commonly used in the ICU and laboratory values relevant to the ICU.

The quintessential example of the mind-body connection, Decoding The Secret Language of Your Body makes everyone aware of even the most subtle interaction between feelings and body responses. Itchy palms...cold feet...a pain in the neck. Not a day goes by that our bodies don't "speak" to us through tickles and tingles, belches and bellyaches -- and psychiatrist Martin Rush takes us on an entertaining, enlightening exploration as he teaches us how to decode these secret signs and signals.

Data interpretation questions based on clinical cases are a popular means of testing medical students both during undergraduate studies and as an element of finals examinations. Written by a small team of authors with extensive teaching experience, 100 Cases in Medical Data Interpretation provides invaluable guidance from lecturers who understand from personal experience that detailed and accurate explanations are the key to successful revision. This book presents 100 cases arranged by specialty area-radiology, clinical chemistry, haematology and cardiology-as well as a random section of miscellaneous cases. Questions accompanying each case prompt the reader to consider how the data presented might be correctly understood. A clear discussion of how the correct answer was reached, with boxed highlights and bullet lists of key points, makes this book an excellent learning aid during all stages of clinical studies, and particularly while preparing for medical finals.

General practitioners and other primary care professionals have a leading role in contemporary health care, which Trisha Greenhalgh explores in this highly praised new text. She provides perceptive and engaging insights into primary health care, focussing on:

- its intellectual roots
- its impact on the individual, the family and the community
- the role of the multidisciplinary team
- contemporary topics such as homelessness, ethnic health and electronic records.

Concise summaries, highlighted boxes, extensive referencing and a dedicated section on effective learning make this essential reading for postgraduate students, tutors and researchers in primary care.

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From the foreword by Julian Tudor Hart
""Trish Greenhalgh, in her frequent columns in the British Medical Journal...more than any other medical journalist spoke to her fellow GPs in the language of experience, but never without linking this to our expanding knowledge from the whole of human science."

"When I compare the outlines of primary care so lucidly presented in this wonderful book, obviously derived from rich experience of real teaching and learning, with the grand guignol theatre of London medical schools when I was a student 1947-52, the advance is stunning.""

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""Trish Greenhalgh is one of the international stars of general practice and a very clever thinker. This new book is a wonderful resource for primary health care and general practice. Every general practice registrar should read this book and so should every general practice teacher and primary care researcher.""

Professor Michael Kidd, Head of the Department of General Practice, University ofSydney and Immediate Past President of The Royal Australian College of General Practitioners

""This important new book by one of primary care's most accomplished authors sets out clearly the academic basis for further developments in primary health care. Health systems will only function effectively if they recognise the importance of high quality primary care so I strongly recommend this book to students, teachers, researchers, practitioners and policy makers.""

Professor Martin Marshall, Deputy Chief Medical Officer, Department of Health, UK

The germs of the ideas in this book became implanted in me during my experience as a resident in clinical pathology at Boston University Medical Center. At the time, I had inklings that the test results churned out by our laboratories were more than scientific facts. As a philosophically unsophisticated young physician, however, I had no language or framework to analyze what I saw as a deep philosophical problem, a problem largely unrecognized by most physicians. The test results provided by our laboratories were accurate and of great practical importance for patient care. However, most of the physicians who relied on our test results to diagnose and treat their patients either did not have the time or interest to consider the philosophical issues inherent in diagnosis, or, like me, had inadequate means to further analyze them. It was more than ten years later that I began doctoral studies in philosophy, and I was fortunate to find a faculty that was supportive of my efforts to address the problem. This book began as my doctoral dissertation in the Department of Philosophy at Georgetown University. I would like to acknowledge the assistance of my mentor, Robert Veatch, Ph. D. Our conversations during my Georgetown years led me in new and often fascinating directions. I would also like to acknowledge the help of Kenneth Schaffner, M. D. , Ph. D.

The definitive companion for medical science study and revision Medical Sciences at a Glance consolidates the scientific knowledge a student needs to know to provide a solid framework of key facts to build on. Concise, easy to follow, written specifically for medical students, and using the unique at a Glance style to convey key concepts, Medical Sciences at a Glance also demonstrates vital links between different topics and across systems. It is the perfect resource for bridging the gap between A-Level and university, studying a new topic, revising for exams, or refreshing knowledge while on placement. Key features: * Fully cross-referenced to Medicine at a Glance: together they cover the core concepts of an entire medical degree * Highlights key points and their clinical relevance for quick revision and retention of what s most important * Brings together all the scientific content on a medical course in one easy-to-read, highly-illustrated title * Accompanied by a companion website at ataglanceseries.com/medicalsciences featuring interactive multiple-choice questions and key points for revision Medical Sciences at a Glance provides the vital scientific grounding needed to succeed at medical school.