This book will help clinicians acquire and develop the processes and skills of values-based practice. The aim of most patient-clinician consultations is to improve health outcomes. Often they succeed, and patients are satisfied and empowered. However, some consultations are unsatisfactory and result in failure to improve health outcomes and dissatisfaction on the part of patients, carers or clinicians. When consultations fail to achieve the desired results, the cause is not usually a failure of evidence-based practice. Today's clinicians are trained in evidence-based medicine, educated, updated and appraised. The most likely reason why things go wrong is a failure of values-based practice - not ascertaining the relevant values perspectives and acting on them in a coherent and purposeful manner. If you rehearse and practise the elements of values-based practice detailed in this book, you will find your consultations more personally rewarding and your patients are likely to derive more benefit.

The Bellevue Guide to Health Care represents a collaboration among primary care and specialist physicians in the Department of Medicine at New York School of Medicine. It is intended for use by teachers, students and practitioners of primary care and in the hospital outpatient department. The Guide presents data about prevalence of disease, accuracy and diagnosis from congestive heart failure to domestic violence. Advice about patient management is interwoven with annotated references in a unique two column format providing the actual data upon which recommendations are based. (For example, recommendations to use statin drugs to treat hypermlipidemia are accompanied by literature based estimates of live-saving potential by statins among various patient groups.)
Readers of The Guide are encouraged to use this data to tailor clinical decisions to meet the needs of their individual patients.

The Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. Divided into five sections, the book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five sections, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy. Comprehensive in scope and written by leading researchers in the field, The Retinoids: Biology, Biochemistry, and Disease will be an essential reference for biologists, biochemists, geneticists and developmental biologists, as well as for clinicians and pharmacists engaged in clinical research involving retinoids.

Common Medical Conditions: A Guide for the Dental Team is an invaluable reference in the Dental Update series of clinical resources outlining the clinical features, clinical signs, diagnosis, management and dental relevance of the most commonly encountered chronic medical problems in the developed world. Written by an internationally renowned and experienced team of authors, the book is a quick and ready illustrated reference giving essential information in an oral health care context to common medical conditions. Designed for easy reference, the book is organised by systems with sections on: Cardiovascular, Respiratory, Metabolic and Endocrine, Gastrointestinal, Haematological, Mental Health, Neurological, Osteoarticular, Mucocutaneous and Infectious Diseases. Covers most commonly encountered chronic medical problems in a dental context Systematic and organised to provide easy cross-referencing Includes useful features such as summaries of key information and comparisons of similar conditions Fully illustrated throughout with colour clinical photography

Awarded First Prize, in the Primary health care category, at the 2013 BMA Medical Book Awards.Following the familiar, easy-to-use "at a Glance" format, this brand new title provides a highly illustrated introduction to the full range of essential primary care presentations, grouped by system, so you'll know exactly where to find the information you need, and be perfectly equipped to make the most of your GP attachment.

"General Practice at a Glance" Is comprehensively illustrated throughout with over 60 full-page colour illustrationsTakes a symptoms-based approach which mirrors the general practice curriculumOffers 'one-stop' coverage of musculoskeletal, circulatory, respiratory, nervous, reproductive, urinary, endocrine and digestive presentationsHighlights the interrelations between primary and secondary careIncludes sample questions to ask during history taking and examinationFeatures 'red flags' to highlight symptoms or signs which must not be missed

This accessible introduction and revision aid will help all medical students and junior doctors develop an understanding of the nature and structure of primary care, and hit the ground running on the general practice attachment.

In this excellent new book, specialist dietitians Isabel Skypala and Carina Venter bring together a team of expert authors to separate fact from fiction and provide the reader with an authoritative and practical guide to diagnosing, managing and preventing food allergy and intolerance.

This new edition of Breast Lumps (which was first published in 1994) provides updated information on both benign breast conditions and breast cancer. The book has been substantially revised, particularly with regard to the changes that have occurred in the treatment of breast cancer during the last few years. It discusses all aspects of the management of breast lumps and the ways in which this differs in the UK and USA.

Hardbound. Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need requiring the attention of medicinal chemists.Five topical subjects are reviewed: the biosynthesis, metabolism and function of Vitamin D3 and the potential application of its analogues in bone disorders and immune-related diseases; the therapeutic potential of neurokinin antagonists; opioid receptor antagonists; the mechanisms of bacterial resistance; and a survey of recent advances in cannabinoid research.This volume will deservedly take its place in clinical and industrial pharmaceutical libraries, and will prove invaluable to medicinal chemists.

Following the GMC's call for greater social and behavioural science input into undergraduate medical education, this brand new title in the Lecture Notes series provides an understanding of how education, social class, family, economics and occupational circumstances, as well as cultural and ethnic influences, shape patients and health professionals alike. A deeper appreciation and understanding of these issues can have a positive effect on clinical diagnosis and practice. Emphasising clinical relevance at all times, the book features photographs and line drawings to illustrate key points, and case studies that provide real-life illustrations of the points discussed. It also contains 'points of view' boxes which encourage critical thinking and challenge the reader to come up with their own explanations for the phenomena described. Lecture Notes: The Social Basis of Medicine provides information and materials useful not only for undergraduate medical students, but also for recently graduated and practising doctors who wish to have a greater understanding of, and to develop their skills in, this area.

Die umfassend uberarbeitete Neuauflage dieses Standardwerks erlautert die grundlegenden Fortschritte in der Forschung und vermittelt so alles Wissenswerte rund um Erkrankungen der Leber. Die neueste Auflage von The Liver: Biology and Pathobiology ist nach wie vor das Referenzwerk in der Hepatologie. Fortschritte in den Biowissenschaften und der Forschung werden in einen direkten Zusammenhang gestellt und erleichtern das Verstandnis zu Struktur, Funktion und krankhafter Pathologie der Leber sowie moeglicher Behandlungsoptionen. Die 6. Auflage wurde komplett uberarbeitet und um die neuesten Erkenntnisse aus der Biologie und deren Einfluss auf Diagnose, Management und Vorbeugung von Lebererkrankungen erweitert. 70 neue Kapitel, darunter grosse Abhandlungen zu Leberkarzinomen und bahnbrechenden Fortschritten mit massgeblichen Auswirkungen fur die Hepatologie, liefern ein umfassendes und aktuelles Bild der Hepatologie von heute und morgen. Zu den Themen gehoeren: RNS-Struktur und -Funktion, Genombearbeitung, Genomanalyse von einzelnen Zellen und Molekulen, Molekularbiologie von Hepatitis, Arzneimittelwechselwirkungen, Medikamentendesign, Mechanismen und Therapien von Lebererkrankungen. Herausgeber sind international renommierte Experten. - Greift auf die molekulare Physiologie zuruck, um die Pathologie und Behandlung von Lebererkrankungen verstandlich zu erklaren. - Stellt einen Zusammenhang zwischen Wissenschaft und Pathologie der Leber und klinischen Anwendungen her. - Enthalt 16 neue Horizons-Kapitel, die neue und zukunftige Forschung und Technologie behandeln. - Mit unzahligen farbigen Illustrationen und Abbildungen. Die 6. Auflage von The Liver: Biology and Pathobiology ist ein Muss fur Hepatologen, angehende Hepatologen, Gastroenterologen, hepatobiliare Transplantationschirurgen, Forscher und Wissenschaftler aus den Bereichen Hepatologie, Zell- und Molekularbiologie, Virologie und Arzneimittelstoffwechsel.

Now in its fully revised and expanded second edition, this volume is the definitive global resource on psychosocial problems. Containing several new chapters and featuring extensively updated contributions from experts in the field, this title takes a uniquely global approach in laying the foundations of bio psychosocial basic care and provides relevant information about the most common mental and psychosomatic problems and disorders. An extension of the cultural aspects of the individual clinical pictures and new contributions from China, Latin America, Russia, Iran, India, Africa and Myanmar, also about migration and mental health accompany this revision. This book is divided into four sections and begins by explaining the relationship between psychosomatic medicine and primary care. The next part outlines the best practices for diagnosing the most common biopsychosocial problems and mastering the most frequent communication challenges (e.g. biopsychosocial anamnesis, breaking bad news, dealing with difficult patients, family and health systems communication and collaboration). The following section delves into more specific psychosomatic problems such as depressive disorders, posttraumatic stress disorder, addiction, the terminally ill patient and eating disorders, among others. The final section focuses on developing psychosomatic medicine in international settings. Every chapter integrates basic theoretical background and practical skills and includes trans-culturally sensitive material, important for work with patients from different nations. Psychosomatic Medicine: An International Primer for the Primary Care Setting, second edition is a must-have reference for doctors from various specialties as well as nursing staff, social workers and clinical health psychologists.

As the profound contribution of mental illness to disability, morbidity, and mortality has gained acceptance, mental health has grown into a global priority. One in five experience mental illness in their lifetime, and those who suffer are coming forward in unprecedented numbers. As more people seek care for themselves and others, providers are increasingly unable to meet the demand through existing systems and mental health care approaches. In Managing Uncertainty in Mental Health Care, Drs. Patricia Rockman and Jose Silveira critically examine core assumptions informing the primary approaches currently used to assess mental illness in clinical settings, with an emphasis on clinician certainty. They illustrate how current diagnostic frameworks obscure clinician uncertainty while encouraging overconfidence and go on to consider potential strategies for lessening the impact of inevitable errors. Ultimately, this book makes a case for acknowledging the fallibility of clinical judgment, independent of competence and experience, and the need to modify approaches to mental health care so that they align with the irreducible uncertainty of the domain. By exploring emerging transdiagnostic approaches to mental health care in terms of their alignment with irreducible uncertainty, Rockman and Silveira make space for error and offer clinicians a novel way to advance the fundamental aim of mental health care: to reduce the harm and suffering of all.

Genetic and Evolutionary Computation: Medical Applications provides an overview of the range of GEC techniques being applied to medicine and healthcare in a context that is relevant not only for existing GEC practitioners but also those from other disciplines, particularly health professionals. There is rapidly increasing interest in applying evolutionary computation to problems in medicine, but to date no text that introduces evolutionary computation in a medical context. By explaining the basic introductory theory, typical application areas and detailed implementation in one coherent volume, this book will appeal to a wide audience from software developers to medical scientists. Centred around a set of nine case studies on the application of GEC to different areas of medicine, the book offers an overview of applications of GEC to medicine, describes applications in which GEC is used to analyse medical images and data sets, derive advanced models, and suggest diagnoses and treatments, finally providing hints about possible future advancements of genetic and evolutionary computation in medicine. * Explores the rapidly growing area of genetic and evolutionary computation in context of its viable and exciting payoffs in the field of medical applications. * Explains the underlying theory, typical applications and detailed implementation. * Includes general sections about the applications of GEC to medicine and their expected future developments, as well as specific sections on applications of GEC to medical imaging, analysis of medical data sets, advanced modelling, diagnosis and treatment. * Features a wide range of tables, illustrations diagrams and photographs.

Allay your anxieties about the MRCP exams and increase your confidence with "An Aid to the MRCP: Essential Lists, Facts and Mnemonics."

In order to pass the MRCP exams you will need to learn a large number of lists and key facts. This book provides the essential lists and facts you need to know together with memory aids to speed learning and recall. Armed with this knowledge you will be able to rapidly narrow your differential diagnosis and identify the most likely answer.

This essential new MRCP title has been written by a recent candidate for the MRCP exams who used this technique to pass first time, in conjunction with Dr Bob Ryder, Dr Anne Freeman and Dr Mir Afzal; all established authorities in the MRCP field and authors of the two volumes of "An Aid to the MRCP PACES."

"An Aid to the MRCP: Essential Lists, Facts and Mnemonics" presents memory aids, facts and lists that are based on questions faced whilst revising for, or encountered during the MRCP exams and also features a free audio revision tool at www.anaidtothemrcp.com with a summary of the mnemonics contained in the book.

In spite of recent changes in nurse education, nurses still need to know about medicine to understand their work with patients. This is the latest edition of what has become a popular and enduring nursing textbook. It is a short textbook of medicine written by medical experts, but read by nurses. Nurses have consistently found this book invaluable because of the level at which the text is pitched. It has been written in consultation with nurses and covers exactly the medical knowledge that they require.These features make it still an ideal medical text for nurses: Includes the medical knowledge nurses need New team of contributors to widen input Written in consultation with nurses to ensure appropriateness of information New format and typeface - to increase readabilityWritten by an up-to-date team of medical experts Includes the medical knowledge nurses need New team of contributors to widen input Written in consultation with nurses to ensure appropriateness of information New format and typeface - to increase readability Well established and highly respected nursing textbook

This socially conscious, culturally relevant book explores the little-known history and present climate of Black people in the medical field. It reveals the deficiencies in the American healthcare structure that have contributed to the mismanagement of healthcare in the Black population, and examines cross-currents that intersect with the major events in minority medical history. Illustrated across 10 expertly written chapters, this text features a longitudinal timeline with the presentation of evidence-based information drawn from historical, political, and clinical sources. The book begins with an analysis of diseases particularly prevalent in the Black community due to socioeconomic inequalities in available medical care. These diseases include sickle cell anemia, hypertension, heart failure, drug addiction, and HIV/AIDS. Bolstered by profiles of historically well-known Black physicians, stories of success in medical education, and the remarkable impact of Black medical organizations, subsequent chapters address the triumphs and tribulations of the Black medical professional in America. Concluding with an examination of the current health status of Black people in the United States, the book makes a case for future systemic improvements in healthcare delivery to minority communities. A unique, noteworthy reference, Blacks in Medicine: Clinical, Demographic, and Socioeconomic Correlations is written for a broad range of physicians and health providers, as well as professionals in the social sciences and public health.

Drawing on interdisciplinary, cross-national perspectives, this open access book contributes to the development of a coherent scientific discourse on social exclusion of older people. The book considers five domains of exclusion (services; economic; social relations; civic and socio-cultural; and community and spatial domains), with three chapters dedicated to analysing different dimensions of each exclusion domain. The book also examines the interrelationships between different forms of exclusion, and how outcomes and processes of different kinds of exclusion can be related to one another. In doing so, major cross-cutting themes, such as rights and identity, inclusive service infrastructures, and displacement of marginalised older adult groups, are considered. Finally, in a series of chapters written by international policy stakeholders and policy researchers, the book analyses key policies relevant to social exclusion and older people, including debates linked to sustainable development, EU policy and social rights, welfare and pensions systems, and planning and development. The book's approach helps to illuminate the comprehensive multidimensionality of social exclusion, and provides insight into the relative nature of disadvantage in later life. With 77 contributors working across 28 nations, the book presents a forward-looking research agenda for social exclusion amongst older people, and will be an important resource for students, researchers and policy stakeholders working on ageing.

This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.

This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.

Illustrating the differences between urgent interventions and interventions performed to manage chronic conditions the authors present the chapters in a consistent template for ease of use covering; background, indications, evidence review, device description, procedural techniques, follow-up care, and complications. * Shows the differences between interventions performed to manage chronic conditions and interventions that are truly urgent * Chapters follow a consistent structure from background through indications, evidence review, device description, procedural techniques to follow-up care and complications * More than 40 high definition videos, hosted on companion website www.wiley.com/go/kipshidze/interventionaltherapies, complete with tips and tricks, provide a visual learning tool

This book presents a unique collection of clinical cases to help combat the difficulty of diagnosis and treatment of Syncope. Medical professionals using this book are provided with a reference to a large array of succinctly described and illustrated clinical scenarios. Each case is presented with the results of appropriate tests and critical comments about the evaluation, diagnosis and treatment according to guidelines. Syncope is considered a difficult diagnostic and treatment problem for all who work in the field. Regardless of your prior knowledge, you will find the case studies easy to digest, enlightening, and immediately pertinent to improving the care patients - giving you confidence in your diagnosis and your advice. The editors have developed a lively and easy-to-read book with a focused expert editorial commentary, offering the reader a broader and easily understood context for each case, as well as key citations from the literature. Syncope Cases is a valuable contribution to your collection; edited by seven prominent authorities on the management of syncope from four countries, with more than 130 contributors, this book provides a unique additional step in the fostering of a better understanding of the many factors that can cause syncope, with the ultimate goal of facilitating the delivery of more precise and cost-effective care for syncope patients. It is a contribution that should be widely read, and one that offers the possibility of distinctly enhancing medical care of the syncope patient.

Stem cells have generated considerable interest recently in the scientific, clinical, and public arenas. It is essential that we gain a broader understanding of the factors that regulate the biology of stem cells: their ability for self-renewal, differentiation, and plasticity, as well as the differences between embryonic and adult stem cells. And to learn whether stem cells can be manipulated to replace cells in diseased tissues depends on better understanding their normal developmental properties.

This volume offers contributions from numerous interdisciplinary areas bridging biotechnology and biomedical sciences. The ability to isolate and maintain pluripotent stem cells in culture offers exciting possibilities for replacing damaged or diseased organs and tissues. Moreover, stem cells will provide opportunities for major advances in our understanding of fundamental developmental processes.

The study of pluripotent stem cells derived from early embryos or fetal tissues has shown that they are capable of replicating indefinitely in vitro and possess the ability to differentiate into many cell types. Biotechnological advances under which growth conditions and factors can be identified and characterized are needed to guide such cells to form organ-specific tissues.

Biomedical researchers are also investigating approaches to isolate and manipulate adult-derived multipotential stem cells that appear to possess considerably broader differentiation capacity than originally imagined.

Novel therapeutic strategies are being developed to take advantage of the ability of stem cells to proliferate in culture and to survive after transplantation into various tissues, where they may integrate and stably express foreign genes, or repopulate damaged or diseased organs such as the heart, brain, or pancreas.

These presentations foster a broader understanding of the factors that regulate the biology and plasticity of stem cells through the picture they provide of the "state of the science" of stem cell biology and by framing the many questions that remain to be answered.

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This 2006 book is a how-to guide for medical students moving from the classroom to the clinical/hospital setting; a particularly stressful transition in a student-physician's career. This handbook is made up of short, easily digestible passages that advise students on everything from reading an EKG or chest x-ray to tips on dealing with difficult residents and what to wear on wards. Passages are peppered with light-hearted anecdotes to bolster the spirits of students intimidated and overwhelmed by their responsibility as fledgling doctors. The handbook has been developed by Dr Richard Loftus, who wrote the first version of this guide after his 3rd year at University of California, San Francisco (UCSF). It contains appendices of useful information, including a PDF file of full size forms that can be accessed from our website.