About this book— In recent years, a number of different spectroscopic techniques have been applied to the study of a wide range of biomedical topics. Biomedical investigations in fields as diverse as eye lens research, the study of cardiovascular and inflammatory diseases, and the study of oxidative stress in disease can now be carried out by spectroscopic means. The nine chapters in Biomedical Applications of Spectroscopy present an authoritative overview of the current status of the field, with each chapter written by acknowledged experts. A wide range of techniques is considered, including optical microspectroscopy, Raman spectroscopy, FTIR spectroscopy, NMR and EPR spectroscopy and mass spectrometry. This highly topical volume will stimulate interest in this expanding field, and point the way towards future directions in research. The major objectives of this established series are to integrate theory and practice and to bring together different branches of both academic and industrial research through the presentation of critical review articles in fundamental and applied spectroscopy. The policy of the editors is to commission authoritative reviews by acknowledged leaders in the various fields of spectroscopy. Thus each volume presents a carefully composed picture of the ‘state of the art’ for a particular area. For each volume the subject matter is presented in a manner which is Comprehensible to the non-expert, for whom the series will continue to provide a valuable introduction, and a timely overview of topics in spectroscopy which are of current interest and importance. At the same time the involved expert will find much to engage his or her attention. The series is of interest to research scientists and technologists, to teachers and both graduate and undergraduate students.

Offering a unified resource for both clinicians and pharmacists, A Medication Guide to Internal Medicine Tests and Procedures provides concise, focused answers to common medication questions before, during, and after internal medicine tests and procedures. Co-authored by experienced physicians and clinical pharmacists, this unique, time-saving reference brings together essential information for healthcare providers and students in a convenient, highly templated, pocket-sized book. Addresses the many medication questions surrounding 54 of the most commonly used tests and procedures. Ensures proper peri-procedural management by addressing what medications need to be administered or held ahead of a specific test. Provides foundational guidance on the diagnostic process, anticoagulation and glycemic management in the periprocedural period, and anesthesia, followed by highly templated chapters arranged alphabetically by procedure name. Includes brief descriptions of tests, how they are performed, and common findings. Helps readers avoid interference with tests and unnecessary adverse effects, optimizing patient outcomes. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Chronic Fatigue Syndrome (CFS) is now a recognized major and international medical concern. Neglected for many years because of its puzzling wide range of symptoms and inability to be "slotted" into any single mainstream medical discipline, CFS has gained government, academic, and public attention. In this innovative book, Dr. Jay Goldstein provides a medical narrative of an "evolving theory" of how the symptoms of CFS may develop through dysfunction of numerous physiological pathways. He describes the biologic basis of these assumptions, and, based on an analysis of basic medical principles, leads the reader to logical conclusions. In addition, Dr. Goldstein reveals a wealth of clinical experience by describing successes and failures of various therapies and discusses the reasons for the outcomes. Dr. Goldstein's private practice is devoted to patients who fit the profile of a CFS sufferer. As a result, his extensive clinical experience has given him a unique hands-on perspective not readily available to most researchers.Chronic Fatigue Syndromes: The Limbic Hypothesis carefully reviews the extant research literature in each chapter. Although Dr. Goldstein cautions that this model should be viewed only as a PROMISING FOUNDATION for future research, no less than six peer reviewers, all leading researchers and clinicians in the CFS field, have endorsed the direction of Dr. Goldstein's bold proposition. The breadth and scope of this book is perhaps best summarized by Paul Cheney, MD, PhD, a national leader in the field:"Despite its long history, the medical establishment with its great advances in biotechnology has been largely unable to crack the basic pathophysiology of the chronic fatigue syndrome. . . . Dr. Goldstein's new book takes us to a place few people know well, and describes a plausible mechanism of injury to the deep brain which could explain every symptom seen in [patients with] chronic fatigue syndrome. . . . It is the unifying power of his hypothesis, together with emerging scientific support for this view, that makes this book an important one to read for both the patient with CFS, as well as the practitioner and medical scientist who attempt to understand it."

Chronic Fatigue Syndrome (CFS) is now a recognized major and international medical concern. Neglected for many years because of its puzzling wide range of symptoms and inability to be "slotted" into any single mainstream medical discipline, CFS has gained government, academic, and public attention. In this innovative book, Dr. Jay Goldstein provides a medical narrative of an "evolving theory" of how the symptoms of CFS may develop through dysfunction of numerous physiological pathways. He describes the biologic basis of these assumptions, and, based on an analysis of basic medical principles, leads the reader to logical conclusions. In addition, Dr. Goldstein reveals a wealth of clinical experience by describing successes and failures of various therapies and discusses the reasons for the outcomes. Dr. Goldstein s private practice is devoted to patients who fit the profile of a CFS sufferer. As a result, his extensive clinical experience has given him a unique hands-on perspective not readily available to most researchers.Chronic Fatigue Syndromes: The Limbic Hypothesis carefully reviews the extant research literature in each chapter. Although Dr. Goldstein cautions that this model should be viewed only as a PROMISING FOUNDATION for future research, no less than six peer reviewers, all leading researchers and clinicians in the CFS field, have endorsed the direction of Dr. Goldstein s bold proposition. The breadth and scope of this book is perhaps best summarized by Paul Cheney, MD, PhD, a national leader in the field: "Despite its long history, the medical establishment with its great advances in biotechnology has been largely unable to crack the basic pathophysiology of the chronic fatigue syndrome. . . . Dr. Goldstein s new book takes us to a place few people know well, and describes a plausible mechanism of injury to the deep brain which could explain every symptom seen in patients with] chronic fatigue syndrome. . . . It is the unifying power of his hypothesis, together with emerging scientific support for this view, that makes this book an important one to read for both the patient with CFS, as well as the practitioner and medical scientist who attempt to understand it."

Series Information:
Brunner/Mazel Eating Disorders Monographs

Household Chemicals and Emergency First Aid is an essential manual that covers 386 household chemicals, discusses their hazards when mixed with other chemicals, describes the symptoms of overexposure, and provides instructions for emergency first aid treatment. The book is intended to be used in the event that label instructions on household chemicals have not been followed. It describes what may possibly happen and how to handle the situation if it does occur. Poison control centers are listed by state with phone numbers and addresses.
Because household accidents involving chemicals are so prevalent, this manual is a "must have" book for all emergency medical technicians, paramedics, and other emergency first aid providers. It is also useful for anyone wanting detailed information regarding emergency situations with household chemicals.

The first edition of this successful reader brought together key readings in the area of developmental cognitive neuroscience for students. Now updated in order to keep up with this fast moving field, the volume includes new readings illustrating recent developments along with updated versions of previous contributions. These revisions ensure that the collection will remain a crucial resource for anyone teaching developmental cognitive neuroscience or cognitive development.

The "Reader" is broad-ranging, covering every aspect of developmental cognitive neuroscience. New pieces for the second edition include writing on individual development and evolution, on the structural and functional development of the brain and on object recognition and sensitive periods, whilst articles updated include those on the neurobiology of cognitive and language processing and self-organization in developmental processes.

Diseases and Diagnoses discusses why such social problems as addiction, sexually transmitted diseases, racial predisposition for illness, surgery and beauty, and electrotherapy, all of which concerned thinkers a hundred years ago, are reappearing at a staggering rate and in diverse national contexts. In the twentieth century such problems were viewed as only historical concerns. Yet in the twenty-first century, we once again find ourselves confronting their implications. In this fascinating volume, Gilman looks at historical and contemporary debates about the stigma associated with biologically transmitted diseases. He shows that there is no indisputable way to measure when a disease or therapy will reappear, or how it may be perceived at any given moment in time. Consequently, Gilman focuses on the socio-cultural and political implications that the reappearance of such diseases has had on contemporary society. His approach is to show how culture (embedded in cultural objects) both feeds and is fed by the claims of medical science-as for example, the reappearance of "race" as a cultural as well as a medical category. If the twentieth century was the "age of physics," in the latter part of the past century and certainly in the twenty-first century biological concerns are recapturing central stage. Achievements of the biological sciences are changing the public's sense of what constitutes cutting-edge science and medicine. None has captured the public imagination more effectively than the mapping of the human genome and the promise of genetic manipulation, which fuel what Gilman calls a "second age of biology." Although not without controversy, the role of genetics appears to be key. Gilman puts contemporary debates in historical context, showing how they feed social and cultural concerns as well as medical possibilities.

A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an inhibitor of gene expression.

For over half a century Davidson's Principles and Practice of Medicine has informed and educated students, doctors and other health professionals all over the world, providing a comprehensive account of the practice of medicine. Davidson's Essentials of Medicine provides the core content of the main textbook in a condensed format which will be invaluable whenever you are on the move - whether commuting, travelling between training sites, or on electives. This book provides a distillation of the core information required for clinical studies in medicine. While retaining the acclaimed readability of the main textbook it presents the key information in a format more appropriate for practical clinical work. The scope of the contents was carefully selected by a team of junior doctors, emphasising only the topics that will be essential for clinical studies. The text draws directly on the depth and breadth of experience of the Davidson's authors and its International Advisory Board. Updated to include key changes and new illustrations included in Davidson's Principles and Practice of Medicine. New chapters on Acute Medicine and Ophthalmology

The Rhetoric of Medicine explores problems that confront medical professionals today by first examining similar problems that confronted physicians in ancient Greece. This framework provides illuminating entry points into challenges faced by the practice of medicine, enabling readers to understand more clearly their shape and operation in the modern context-as well as possible solutions to these problems. Topics covered include: larger cultural ideas about the body; tension between professional values and working for money; effective collaboration and competition with alternative healthcare providers; restrictions on political involvement that seem part of a physician's identity; maintaining a space for professional autonomy and judgment; mentoring that is effective but not exclusive; and physicians' recognition of themselves as patients as well as professionals. The Rhetoric of Medicine represents a unique collaboration between a classicist and a neurosurgeon, reflecting both their scholarly work and extensive experience as administrators. Together, these two experts combine their personal experience as professionals with careful analysis of what it means to be a medical professional, both in ancient Greece and today. The Rhetoric of Medicine is a call to interrogate the narratives and ideas that shape medical care and to revise and replace those that do not serve patient health. Advance Praise for The Rhetoric of Medicine "It is an incredibly rich story with lessons around money, competition and autonomy for doctors and for the patients they serve." - Sanjay Gupta, MD, Staff Neurosurgeon, The Emory Clinic, Atlanta, GA, Chief Medical Correspondent, CNN

Interpreting the fluid requirements of a patient and working out what to do next can seem like a daunting task for the non-specialist, yet it is a skill that any doctor, nurse or paramedic needs to be fully appraised of and comfortable with. Making Sense of Fluids and Electrolytes has been written specifically with this in mind, and will help the student and more experienced practitioner working across a variety of healthcare settings to understand why fluid imbalance in a patient may occur, to assess quickly a patient's fluid needs through a thorough clinical assessment and to develop an effective management plan. Reflecting the latest guidelines, this practical, easy-to-read and easy-to remember guide will be an invaluable tool to aid speedy and appropriate management in emergency situations, on the ward and in the clinic.

First published in 1987. Routledge is an imprint of Taylor & Francis, an informa company.

Should editing the human genome be allowed? What are the ethical implications of social restrictions during a pandemic? Is it ethical to use animals in clinical research? Is prioritizing COVID-19 treatment increasing deaths from other causes? Bioethics is a dynamic field of inquiry that draws on interdisciplinary expertise and methodology to address normative issues in healthcare, medicine, biomedical research, biotechnology, public health, and the environment. This Is Bioethics is an ideal introductory textbook for students new to the field, exploring the fundamental questions, concepts, and issues within this rapidly evolving area of study. Assuming no prior knowledge of the subject, this accessible volume helps students consider both traditional and cutting-edge questions, develop informed and defensible answers, and evaluate the strengths and weaknesses of a diverse range of ethical positions in medicine. The authors avoid complex technical terms and jargon in favor of an easy-to-follow, informal writing style with engaging chapters designed to stimulate student interest and encourage class discussion. The book also features a deep dive into the realm of global public health ethics, including the response to the COVID-19 pandemic. It considers topics like triage decision-making, the proportionality of society's response to COVID-19, whether doctors have a professional obligation to treat COVID-19 patients, and whether vaccines for this virus should be mandatory. A timely addition to the acclaimed This Is Philosophy series, This Is Bioethics is the ideal primary textbook for undergraduate bioethics and practical ethics courses, and is a must-have reference for students in philosophy, biology, biochemistry, and medicine.

Health Information Exchange (HIE): Navigating and Managing a Network of Health Information Systems allows health professionals to appropriately access, and securely share, patients' vital medical information electronically, thus improving the speed, quality, safety, and cost of patient care. The book presents foundational knowledge on HIE, covering the broad areas of technology, governance, and policy, providing a concise, yet in-depth, look at HIE that can be used as a teaching tool for universities, healthcare organizations with a training component, certification institutions, and as a tool for self-study for independent learners who want to know more about HIE when studying for certification exams. In addition, it not only provides coverage of the technical, policy, and organizational aspects of HIE, but also touches on HIE as a growing profession. In Part One, the book defines HIE, describing it as an emerging profession within HIT/Informatics. In Part Two, the book provides key information on the policy and governance of HIE, including stakeholder engagement, strategic planning, sustainability, etc. Part Three focuses on the technology behind HIE, defining and describing master person indexes, information infrastructure, interfacing, and messaging, etc. In Part Four, the authors discuss the value of HIE, and how to create and measure it. Finally, in Part Five, the book provides perspectives on the future of HIE, including emerging trends, unresolved challenges, etc.

Biological safety is a critical requirement when working with or around infectious disease agents. To prevent exposures and keep staff and patients safe, laboratories and health care facilities rely on personal protective equipment, standard operating procedures (SOPs), and engineering controls. In an instant, however, a single inappropriate human behavior can negate any of these safeguards. This reference provides an important call to action for anyone who relies on safety plans to consider carefully the humans who must follow those plans. Written by an expert in behavioral biosafety training, Prepare and Protect offers a common-sense program for addressing and reducing the risk factors of human behavior. Learn how to Examine the safety culture of your organization and its approach to risk Motivate the compliance, adherence to rules, and community thinking that keep everyone safe Evaluate, validate, and verify SOPs and staff competence Create safety plans and safety training programs that connect outcomes to behaviors Provide leadership that translates the containment philosophy from words to actions The critical message of this book is illustrated and enriched by personal accounts from infectious disease pioneers, from lab safety directors and trainers to the researchers and health care workers directly affected by infectious hazards. If your work involves pathogenic microbes-whether treating patients in a hospital emergency department or conducting research in a biosafety level 2 or higher laboratory-or overseeing those who do these jobs, this resource will teach you how to develop a culture of biosafety through behavior.

In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixed treatment comparisons, Markov models of disease progression, and epidemiology models). A comprehensive, coherent framework is adopted and estimated using Bayesian methods.

"Key features: "A coherent approach to evidence synthesis from multiple sources.Focus is given to Bayesian methods for evidence synthesis that can be integrated within cost-effectiveness analyses in a probabilistic framework using Markov Chain Monte Carlo simulation.Provides methods to statistically combine evidence from a range of evidence structures.Emphasizes the importance of model critique and checking for evidence consistency.Presents numerous worked examples, exercises and solutions drawn from a variety of medical disciplines throughout the book.WinBUGS code is provided for all examples.

"Evidence Synthesis for Decision Making in Healthcare" is intended for health economists, decision modelers, statisticians and others involved in evidence synthesis, health technology assessment, and economic evaluation of health technologies.

This book brings together a collection of methods for the successful detection, culture and investigation of H. pylori, and its associated diseases. Chapters guide the reader through overviews on H. pylori infection, protocols for analyzing human clinical samples, and protocols for characterizing H. pylori, its functional components and its interactions with host cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Helicobacter pylori: Methods and Protocols aims to be a useful practical guide to researchers to help further their study in this field.

This Rapid Review is a concise, evidence-based guide to the diagnosis and treatment of rheumatological and musculoskeletal disorders. Covering the basic principles of joint examination and key clinical skills, the book describes more than 100 clinical cases especially chosen to illustrate both commonly occurring and more unusual conditions. Each case presentation replicates a real-life situation in the busy world of a typical clinic and is illustrated with superb quality colour clinical photographs. Following the case presentation, a series of questions are posed to simulate the diagnosis process along with answers to the questions and a final diagnosis. Tables with lab values supplement the photos and text. Following the case presentations, the book discusses the top ten rheumatological disease categories including rheumatoid arthritis, spondyloarthropathies, lupus, vascultis and other miscellaneous conditions. The book will become an essential 'go to' text for all trainee rheumatologists and general medical practitioners, including specialist nurses, manual therapists and related health professionals. Key Features: Presents clinicians with a series of both common and challenging case presentations that depict the investigation and management of patients with rheumatological and musculoskeletal conditions Covers basic principles as well as the necessary clinical skills Includes more than 100 case presentations with numerous colour illustrations of the highest quality Features a concise format ideal for rapid revision and exam preparation

Across all cultures parenting is the foundation of family life. It is the domain where adult mental health meets infant development. Beginning in pregnancy, parenting involves many conscious and unconscious processes which have recently been shown to affect a child's development significantly. This book focuses on pregnancy and the first year of life, providing a thorough account of the points of encounter between adult and infant psychiatry. In a fresh and comprehensive way, it summarises knowledge about early parenting, including a critical analysis of parenting, what it means to be a "good enough parent," and its relationship to infant, parent and family outcomes. In addition to the psychiatric dimension, the book emphasises the biological aspects of parenting, parental psychopathology and normal and abnormal infant development.

Praise for "Parenting and Mental Health"

"""Tyano, Keren, Herrman and Cox have edited a thoughtfully prepared guide on normal and abnormal parenting. They have, with enormous skill and wisdom, helped to unite the important aspects of pregnancy, infant and childhood development and parenting for adult and child and adolescent psychiatrists. World-class internationally recognized clinicians and researchers help make this book useful throughout the world. This is a masterful, culturally sensitive and important book which provides a long overdue and much needed guide on relationships among children, parents and families."
--"Michelle Riba, M.D., M.S., " Professor and Associate Chair for Integrated Medical and Psychiatric Services, Department of Psychiatry, University of Michigan, USA

"During recent decades, progress in the field of infant mental health has been revolutionary; at the same time, there has been rapid development in women's mental health. By bringing these two together, this pioneering book leads its readers to the vital new focal point around perinatal mental health. The book integrates the origins of developmental psychiatry in attachment and systemic contexts and shows concretely how relationship experiences and biology interact when new life begins.

After describing the fascinating world of early parenting, the book focuses on problems, difficulties and disorders during this phase of life and above all on how to support, intervene and treat disorders in parenting. When infants, mothers and fathers are understood in a holistic way, professionals in many fields will be able to promote the transmission of meaningful life through parenthood and parenting."
--"Tuula Tamminen," Professor of Child Psychiatry, University of Tampere, Finland; Past-President of World Association for Infant Mental Health, President of European Society for Child and Adolescent Psychiatry

Cover design by Reouth Keren

Written with the student in mind, Netter's Introduction to Clinical Procedures, by Drs. Marios Loukas, R. Shane Tubbs, and Joseph Feldman, uses the well-known Netter anatomy art as a foundation for reinforcing the relevant clinical anatomy needed to successfully understand and perform basic procedures. Learn the practical application of this knowledge with step-by-step guides incorporating concise text, interactive images, and animation. Didactic Netter illustrations provide clear informative visuals for quick understanding of anatomical relationships. Concise explanations enhance understanding of clinical underpinnings and implications. More than 30 common clinical procedures are explained and demonstrated with step-by-step illustrations. Multiple choice questions reinforce key concepts and challenge your knowledge. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, animation, "test yourself" images, and references from the book.

ABC of Dementia is a practical guide, written with the needs of professionals in training in mind. Its aim is to enable readers to explore attitudes towards dementia, and find the knowledge and skills required in the important task of supporting the lives of people with dementia and their carers. This new edition is designed to assist students and practitioners working within both primary and secondary care settings with the diagnosis, treatment and provision of care. It covers the causes of dementia, diagnostic assessment, early intervention, pharmacological treatment, person-centred care, legal and ethical issues, and more. This resource has been thoroughly revised to reflect the most recent research and evidence-based practice. New and expanded content addresses dementia and frailty in care homes, explores the role of technology in the treatment of dementia, discusses working with minority groups, and examines case studies. Aids healthcare professionals in developing the knowledge, skills and confidence to care for those with dementia Highlights the importance of person-centred care and the effects of dementia on families and carers. Describes the cognitive changes and neurological disorders central to dementia Addresses the needs of younger people developing dementia Provides guidance on managing dementia in primary care, the acute hospital and end-of-life care settings Covers the Neuropsychiatric Symptoms of Dementia (NPSD) Features numerous full-colour photographs and illustrations ABC of Dementia is a must-have for healthcare students, general practitioners, and other healthcare professionals caring for people with dementia. It will also be of interest to members of the general public who wish to know more about dementia.

How can suicide be prevented and treated by mental health professionals?
This book offers a clinical guide to the assessment, treatment and prevention of suicidal behaviour, from a new and useful theoretical perspective - a developmental process approach. The book presents the arguments and research evidence that suicidal behaviour is not just a response to current emotional crises, but is influenced by persistent characteristics that can be defined in psychological and biological terms.
The authors bring together research-based evidence that establishes three key aspects of the developmental process approach: suicidal behaviour results from the interaction between stressful life events and an individual vulnerability; this individual vulnerability is itself the product of psychobiological factors, genetics and past life events; vulnerability, in this sense, influences how the individual perceives, interprets and reacts to adverse life events, perhaps leading to hopelessness and suicidal behaviour.
Psychologists, psychiatrists, nurses and other mental health practitioners will appreciate the conceptual and clinical value of this book based on its:

• Description of biological and psychological developmental processes leading to suicide, integrating evidence-based information from a broad range of disciplines
• Psychobiological definition of long- and short-tem risk factors for suicide, and innovative approach to psychological and biological targets for treatment and prevention
• Cutting-edge discussion of implications for the study and treatment of suicidal behaviour, by some of the leading authorities in the field.