Cardiac resynchronization therapy is a new therapy for advanced heart failure patients. This therapy has been shown to improve quality of life, exercise capacity, NYHA classification, and even reverse the detrimental "reverse remodeling" that occurs in advanced heart failure - in patients already receiving optimal pharmacological therapy.

The typical patient has NYHA III/IV HF symptoms, a QRS > 120 ms, LVEDD > 55 mm, without any indication required for pacing. The therapy is available in an ICD device, too. CRT has been shown to be effective in patients with both ischemic and non-ischemic cardiomyopathy.

The implant procedure is part of a learning curve. Many physicians who already perform electrophysiology procedures, or PPM, or ICD implants are the ideal implanter - but are surprised at the challenges this implant presents. This book will help "flatten" the learning curve for new physician implanting, and will provide a "guide' for those who have already started implanting.

The success rate is about 90o after 10 years of application, we have found that there are still patients who do not get access to this great therapy because of the complexity of the patient's anatomy, or physician skills.

The book is written by three authors with a great deal of experience culminating in over 3000 cases between them.

This book is intended for cardiologists who currently implant either or both pacemakers and cardioverter defibrillators with cardiac resynchronization therapy (also called bi-ventricular pacing), or plan to implant in the future. This book will be extremely useful for the new cardiologist in training who is learning to implant devices.

The first edition of "An Aid to the MRCP Short Cases" rapidly estabished itself as a classic and has sold over 25,000 copies.

The aims of this revised and extended second edition are the same as those of the first: to provide a comprehensive guide for those preparing for the short cases section of the Membership of the Royal College of Physicians examination. The MRCP examination is a major hurdle for all trainee hospital physicians and has a failure rate of over 70%.

The largest part of the book consists of 200 short cases that are presented in order of frequency of their occurrence in the examination (based on an extensive survey of successful candidates). The clinical features of each case are fully covered and supported by illustrations and photographs. The emphasis throughout the book is on examination technique and how to present the clinical information in the style that the examiners expect. In short, it is an indispensable guide for anyone preparing for this critical examination.

Clinical Chemistry: Principles, Techniques, and Correlations, Ninth Edition is the most student-friendly clinical chemistry text available today.

The Ninth Edition keeps students at the forefront of what continues to be one of the most rapidly advancing areas of laboratory medicine with clear explanations that balance analytic principles, techniques, and correlation of results with coverage of disease states.

The book not only demonstrates the how of clinical testing, but also the what, why, and when of testing correlations to help students develop the knowledge and interpretive and analytic skills they'll need in their future careers.

This is the first critical edition and translation of the first Islamic medical work on fevers. Zad almusafir is perhaps the most influential handbook in the history of medical science, and Gerrit Bos's provides invaluable insight into the medical theory of Book Seven.

Offering a unified resource for both clinicians and pharmacists, A Medication Guide to Internal Medicine Tests and Procedures provides concise, focused answers to common medication questions before, during, and after internal medicine tests and procedures. Co-authored by experienced physicians and clinical pharmacists, this unique, time-saving reference brings together essential information for healthcare providers and students in a convenient, highly templated, pocket-sized book. Addresses the many medication questions surrounding 54 of the most commonly used tests and procedures. Ensures proper peri-procedural management by addressing what medications need to be administered or held ahead of a specific test. Provides foundational guidance on the diagnostic process, anticoagulation and glycemic management in the periprocedural period, and anesthesia, followed by highly templated chapters arranged alphabetically by procedure name. Includes brief descriptions of tests, how they are performed, and common findings. Helps readers avoid interference with tests and unnecessary adverse effects, optimizing patient outcomes. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Individuals with childhood-onset physical and developmental disabilities often have special needs around exercise and physical activity. However, most books on this topic are written for exercise science experts who may not always be the frontline service provider. The aim of this practical guide is to enable clinicians, and others involved in the provision of rehabilitation services to train and foster physical activity and physical fitness across the lifespan. It includes chapters on the principles of fitness testing and training, how to engage safely in physical activity, how to measure physical activity levels tracking progress and what to do if pain arises. It includes disorder-specific chapters that apply the general principles of physical activity training to specific diagnoses including autism, traumatic brain injury and juvenile arthritis.

There is growing pressure to ensure that patients receive care that is proven effective and subsequently, a tremendous need to train mental health practitioners in the latest in Evidence-Based Practice (EBP). "Evidence-Based Treatment Planning for Posttraumatic Stress Disorder DVD Companion Workbook" covers presenting problems stemming from anxiety after a traumatic event. The DVD (sold separately) demonstrates the techniques and treatment interventions covered in the lecture. This workbook guides staff in implementation of the interventions with their clients subsequent to the DVD training. Ideal for training mental health professionals at any level.

Professional counselling practice is full of complexities and subtleties, yet the richness of clinical counselling still receives insufficient recognition in the literature and in public opinion.
In the light of the current professionalization of counselling, Clinical Counselling in Context: An Introduction examines the hypothesis that counselling theory and practice is altered by the specific organizational context in which it takes place - the consequence of which is that context is an important force for therapeutic change. It also argues that, with careful professionalization and a well-thought-out academic base, counselling can be a sophisticated activity which is not just the poor neighbour of psychotherapy.

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The Annual Update compiles reviews of the most recent developments in clinical intensive care and emergency medicine research and practice in one comprehensive book. The chapters are written by well recognized experts in these fields. The book is addressed to everyone involved in intensive care and emergency medicine, anesthesia, surgery, internal medicine, and pediatrics.

Coumarins are a group of compounds that have important roles as food constituents; as anti-oxidants, stabilisers, and immunomodulatory substances; as fluorescent markers for use in analysis, in lasers and in clinical use. Coumarins: Biology, Applications and Mode of Action predominantly focuses on the parent compound, coumarin, and its main metabolite in humans, 7-hydroxycoumarin. It describes in detail every facet of these compounds including history, toxicology, chemistry, metabolism, analysis, clinical, veterinary and other applications, their roles as immunomodulatory agents and speculates on their mode of action. Features include:
* New insights into mode of action of coumarins
* Comprehensive summary of new coumarin compounds
* Detailed accounts of methods used for analysis
* Applications of coumarins for diverse methods of analysis
This volume will be of interest to those working in biochemistry, chemistry, pharmacology, clinical sciences and toxicology.

GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding the mortality and morbidity of cancer, and how we can prevent, diagnose, and treat the disease. Prevention of cancer is essential for saving lives. Prevalence and incidence of cancer are key factors that each government and population must be aware of. Advances in the study of cancer occur on a regular basis, and this book provides the latest insights about relationships between the disease and stem cells, tumorigenesis, molecular interactions, pathways, channels, and immunity. Global Epidemiology of Cancer: Diagnosis and Treatment meets the needs of readers by providing current information about epidemiology (including molecular epidemiology), diagnosis, and treatment. Providing logical, step-by-step information on various cancers, this book consolidates all of the most up-to-date information and data from verified studies on all different types of cancers in the United States and throughout the world. Chapters are presented so that each includes an overview, clinical manifestations, epidemiology, pathophysiology, etiology and risk factors, diagnosis, treatment, prevention, and prognosis. Global Epidemiology of Cancer: Diagnosis and Treatment will be invaluable to graduate and postgraduate students, including medical students; nurses; physician assistants; residents in oncology; public health students and allied health students.

Estimating the risk for suicidal behavior among patients is often a very complex challenge for psychiatrists, general practitioners, psychologists, surgeons, specialists in internal medicine, neurologists, nurses, and social workers. Disease, Pain, and Suicidal Behavior is designed to help you understand the methodological problems involved in the assessment of risk for suicidal behavior in patients with various somatic and psychiatric disorders so you can establish effective approaches to the psychosocial treatment of endangered patients. Through the book s comprehensive and insightful discussions, you will even learn specific strategies for improving the quality of life of such patients.Disease, Pain, and Suicidal Behavior discusses psychiatric disorders such as depression, schizophrenia, personality disorders, anxiety disorders, and alcohol and drug abuse as risk factors for suicidal behavior. From its helpful and clearly written pages, you will also learn about the role of social factors in suicidal behavior and the relationship between suicidal behavior and biological factors. Perhaps most important of all, you will learn which groups of patients and which disorders are associated with the highest risk of suicide through the book s critical discussions of: the lifetime risk of suicide in depressed patients the stages of diseases like multiple sclerosis and the strains placed on the patient young male schizophrenics and their vulnerability to self-destructive acts mortality in patients with spinal cord injuries forced reduction in daily activities for patients with heart and lung conditions and resulting emotional instability the high risk of suicide immediately after a cancer diagnosis is given identifying risk factors for a second attempt at suicide questions to ask those at risk for suicidal behaviorRecognizing which of your patients run the risk of committing suicide can be an overwhelming task because of the multiplicity of factors involved. Disease, Pain, and Suicidal Behavior, because it examines critically the existing literature and studies on suicide and suicide risk, can help you evaluate and prevent suicidal behavior in a timely manner. You will turn the last of its pages with a much improved understanding of which illnesses and sufferings present an increased risk of suicidal behavior.

Estimating the risk for suicidal behavior among patients is often a very complex challenge for psychiatrists, general practitioners, psychologists, surgeons, specialists in internal medicine, neurologists, nurses, and social workers. Disease, Pain, and Suicidal Behavior is designed to help you understand the methodological problems involved in the assessment of risk for suicidal behavior in patients with various somatic and psychiatric disorders so you can establish effective approaches to the psychosocial treatment of endangered patients. Through the book s comprehensive and insightful discussions, you will even learn specific strategies for improving the quality of life of such patients.Disease, Pain, and Suicidal Behavior discusses psychiatric disorders such as depression, schizophrenia, personality disorders, anxiety disorders, and alcohol and drug abuse as risk factors for suicidal behavior. From its helpful and clearly written pages, you will also learn about the role of social factors in suicidal behavior and the relationship between suicidal behavior and biological factors. Perhaps most important of all, you will learn which groups of patients and which disorders are associated with the highest risk of suicide through the book s critical discussions of: the lifetime risk of suicide in depressed patients the stages of diseases like multiple sclerosis and the strains placed on the patient young male schizophrenics and their vulnerability to self-destructive acts mortality in patients with spinal cord injuries forced reduction in daily activities for patients with heart and lung conditions and resulting emotional instability the high risk of suicide immediately after a cancer diagnosis is given identifying risk factors for a second attempt at suicide questions to ask those at risk for suicidal behaviorRecognizing which of your patients run the risk of committing suicide can be an overwhelming task because of the multiplicity of factors involved. Disease, Pain, and Suicidal Behavior, because it examines critically the existing literature and studies on suicide and suicide risk, can help you evaluate and prevent suicidal behavior in a timely manner. You will turn the last of its pages with a much improved understanding of which illnesses and sufferings present an increased risk of suicidal behavior.

Provides composite case studies of emotional abuse victims, who with the help of intervention, therapy, and advocacy are moved from states of despair upward to the path of recovery and survivorhood. Intervention, therapy, and advocate are all perspectives used to capture the range of innovative methods for treating emotional abuse survivors. Family and community resources are utilized with an emphasis on the reconnection process integral to moving from victim, to survivor of emotional abuse.

Examines how evidence-based medicine can be applied in general practice, and how its benefits can be realized in the form of effective treatments. It argues for rational rationing, using clinical effectiveness to exclude ineffective measures.

Der Arzneiverordnungs-Report ist seit 1985 eine gemeinsame Publikation von Autoren aus Pharmakologie, Klinik, Praxis, Gesundheitsoekonomie und Krankenversicherung. Basis sind die Verordnungsdaten von Arzneimitteln fur ambulante Patienten der gesetzlichen Krankenversicherung (GKV). Datenbasis des Jahres 2020 sind ca. 820 Mio. Verordnungen von 150.363 Vertragsarzten und 62.876 Vertragszahnarzten fur 73,4 Mio. GKV-Versicherte. Die allgemeine Verordnungs- und Marktentwicklung wird in 6 Kapiteln behandelt, in denen u.a. neue Arzneimittel des Jahres 2020, die Kosten-Nutzen-Analyse von onkologischen Arzneimitteln, Marktsteuerungsmechanismen und Preise von Biologika bzw. Biosimilars sowie die Klassifizierung von Arzneistoffgruppen diskutiert werden. Die Nettokosten fur Arzneimittel in der GKV sind 2020 weiter um 5 % auf rund 46 Mrd. gestiegen, vor allem durch neue, hochpreisige Patentarzneimittel. Hauptkostentreiber waren Onkologika (9,5 Mrd., + 12,4 %) und Antidiabetika (2,8 Mrd., + 16,8 %). Ein wesentlicher Grund fur die Kostenprobleme ist der seit Jahren beobachtete Anstieg der Jahrestherapiekosten neu eingefuhrter Arzneimittel. Dieser Trend zu hochpreisigen Patentarzneimitteln ist durch das Arzneimittelmarktneuordnungsgesetz (AMNOG) sogar 10 Jahre nach seiner Einfuhrung nicht genugend abgeschwacht worden, auch wenn mit der Vereinbarung von Erstattungsbetragen 2020 insgesamt 3,7 Mrd. an Einsparungen erzielt werden konnten.

This authoritative reference surveys mind-body healing concepts and psychosomatic medicine in diverse countries and regions of the world. It provides practical insights on the Western division between medical and mental healing and useful information concerning recent efforts to bridge that enduring divide, particularly in the use of ancient and indigenous healing knowledge in psychosomatic practice. Coverage compares and contrasts current applications of psychosomatic medicine and/or consultation-liaison psychiatry as conducted in such representative countries as France, Britain, China, India, Argentina, Canada, and the United States. And the book predicts how this synthesis of traditions and advances will progress as it: Traces the history and development of psychosomatic medicine. Reviews contributions of traditional healing methods to psychosomatic medicine. Analyzes national styles of psychosomatic medicine as practiced in specific countries. Compares the status of psychosomatic medicine / consultation-liaison psychiatry in various countries. Considers the future of psychosomatic medicine as the field, and the world, evolves. Global Psychosomatic Medicine and Consultation-Liaison Psychiatry expands the knowledge base for psychiatrists, primary care physicians, psychiatric and primary care residents, medical students, behavioral medicine specialists, and others who are interested global and regional perspective on providing biopsychosocial care. It is also relevant for advanced students in health psychology and behavioral medicine, and for professionals in related health fields.

The explosion of knowledge in the fields of neurobiology, psychology and genetics has made it no longer helpful to discuss whether or not a particular illness is psychosomatic. This title provides an introduction to psychosomatics for counsellors and psychotherapists who want to learn about the psychologically informed management of their patients' physical symptoms. It is also intended for general practitioners who are interested in the role of emotions in the formation of physical symptoms.

In recent years the study of illness as experienced by patients has emerged as an approach to understanding sickness. Descriptions of the everyday situations of people with particular diseases, provide a commentary upon the nature of symptoms and upon the relation of the body to society. This approach stresses the biographical and cultural contexts in which illness arises and is borne by individuals and those who care for them. It emphasises the need to understand illness in terms of the patients own interpretation, of its onset, the course of its progress and the potential of the treatment for the condition.
Worlds of Illness examines people's experience of illness and their understanding of what it means to be healthy. The contributors are the first to offer this biographic and cultural approach in one volume, redefining the perspective further and drawing attention to its potential for questioning theoretical assumptions about health and illness.

The Objective Structured Clinical Examination or OSCE for short is a familiar and often daunting experience for medical students. This book provides the essential information needed to tackle OSCE stations competently and with confidence. Over 150 topics are covered at the perfect level of detail for candidates preparing for final exams. Using bulleted checklists and a succinct writing style, the authors cover the most important points to remember about the key conditions that students are likely to encounter during OSCEs, all in a brief 2 to 4 pages per condition.

This timely and important work looks at the collaborative health care model for the delivery of mental health care in a primary care setting. This has become the ideal model for the treatment of comorbid medical and psychiatric or psychological disorders. There is also an increased awareness that pharmacological intervention, the most frequently delivered intervention for psychological disorders, is often of limited effectiveness without concurrent specific psychological intervention. The book includes more than two dozen case studies, co-written by clinical psychologists and primary care physicians. It is essential reading for any psychology practitioner in a clinical setting, as well as for health care administrators.

?The presentation is consistently excellent. One, the writing is lucid and organized in a way that should be very natural for the clinical reader. Two, the text requires no background in mathematics and uses a minimum of symbols. And, three, the methodological concepts and clinical issues are well integrated through a number of carefully prepared and comprehensive examples.? Greg Samsa, Associate Director, Duke Center for Clinical Health Policy Research If a patient is older or younger than, sicker or healthier than, taller or shorter than or simply different from the subjects of a study, do the results pertain? Clinical Epidemiology & Evidence-based Medicine is a resource for all health-care workers involved in applying evidence to the care of their patients. Using clinical examples and citing liberally from the peer-reviewed literature, the book shows how statistical principles can improve medical decisions. Plus, as Katz shows how probability, risk and alternatives are fundamental considerations in all clinical decisions, he demonstrates the intuitive basis for using clinical epidemiolgy as a science underlying medical decisions. After reading this text, the practitioner should be better able to access, interpret, and apply evidence to patient care as well as better understand and control the process of medical decision making.