This book helps to recognize the rights of refugees and provides a framework to identify and approach health needs, from basic elements like service mapping and initial interventions to more complex elements of ongoing healthcare and support and broader topics such as migration public health, migration policy and health systems. Beyond biomedical frameworks, it draws on socio-ecological models to inform assessments and integrated models of care to improve health and health equity. Set out in three comprehensive sections: public health theory (Part 1), applied public health (Part 2), and clinical approaches (Part 3), this book draws on multiple disciplines and insights from humanitarians, academics, policy experts, and clinicians from diverse contexts, with expertise in forced migration, to create an accessible reference tool to inform healthcare professionals' interactions with forcibly displaced individuals and populations in all contexts for both high and low resource countries. Apart from providing information across the spectrum of health issues, clinical specialties and global contexts, it discusses associated areas, including human rights and law, public health, medical anthropology and cultural awareness. Key Features: Bridges the gap between existing academic literature on refugee health and guidelines for health management in humanitarian emergencies Helps to develop an integrated approach to healthcare provision, allowing healthcare professionals and humanitarians to adapt their specialist knowledge for use in forced migration contexts and with refugees. Recognizes the complex and interconnected needs in displacement scenarios and identifies holistic and systems-based approaches. Covers public health theory, applied public health and clinical aspects of forced migration.

The MRCP PACES examination is a highly sought-after qualification worldwide and an essential part of postgraduate medical training in the UK. Fully up-to-date with the current exam format, the Pack also reflects the recent changes to Station 5. In each of these two volumes, the authors include clinical cases which mimic the style and approach of the MRCP PACES exam. These sample cases equip the reader attempting the exam with the skills and knowledge necessary for success, and provide an overview of evidence-based medicine for competency-based training. Across both volumes, the authors explore all aspects of the candidate's performance, from clinical examination, to presentation, communication and medical ethics and up-to-date clinical evidence.
This two-volume pack represents great value to the reader and offers a complete revision packages for the MRCP PACES exam.
Volume 1 includes over 150 cases, covering Stations 1, 3 and 5.
Volume 2 includes 75 cases, covering Stations 2 and 4.

Developments in biochemistry have contributed immensely to the rate at which medical knowledge has expended in recent years. Following the GMC recommendations regarding undergraduate medical education, Biochemistry for Clinical Medicine integrates, in a single volume, all aspects of biochemistry required by a medical student, with a special focus on information specific to medicine as opposed to laboratory-based biochemistry. The first section of the book provides an understanding of basic cell biology and the critical concepts of membrane transport, cellular energetics, information storage, transmission and expression, as well as describing the essential chemistry and metabolism of cellular biomolecules and the clinical conditions that arise from disturbances in their metabolism. The second section adopts a systems-based approach to present clinical biochemistry in an easily readable and concise manner, using tables and clear diagrams to summarise important facts, as well as providing information on the biochemical basis of good nutrition.

Assisted reproduction techniques have led to the birth of 8 million babies worldwide Assisted reproduction techniques (ART), in particular in-vitro fertilization and intra-cytoplasmic sperm injection, are the most advanced forms of infertility treatment. They involve numerous counseling, medical, surgical and laboratory-based steps. At each step various problems and complications could be encountered that challenge even the most experienced ART practitioners. Moreover, patients with complex medical disorders may require ART, presenting further challenges. Assisted Reproduction Techniques will stimulate resourceful thinking in the ART practitioner when faced with these challenges. It outlines various management options, the reasoning behind them, and the evidence on which they are based to enable the practitioner to choose the most suitable solution for the needs of each patient. Written by 171 internationally renowned experts, Assisted Reproduction Techniques follows the patient's journey throughout the whole ART process, with chapters on: Counseling and preparation Pituitary suppression and ovarian stimulation Oocyte retrieval Embryo transfer The luteal phase The ART laboratory The male patient The ART pregnancy General and organizational issues Each of the 116 concise chapters includes clinical cases, background, evidence-based practical management options, preventive measures, key-point summaries of the important details and answers to questions patients ask. Assisted Reproduction Techniques first edition has established its place as a "must read" for ART trainees and practitioners alike, and in this second edition all chapters have been updated, with the addition of new ones addressing training issues, organizational and business skills, and social media use in ART.

This new edition of this standard has been extensively revised to serve the ever-increasing number of investigators who, with only a year or so of statistical training, are performing sophisticated statistical analyses on computers. It provides sound statistical methodology, practical advice on the application of this methodology, and information relating the statistics to computer manipulation and output.

"Diagnostic Techniques in Genetics" offers a comprehensive coverage of the theory and practice of the molecular biology techniques used within medical genetics. The first part of the book focuses on DNA/RNA applications and includes many of the latest developments in the field combined with routine procedures of genetic diagnoses, for example cling and sequencing DNA. The DNA applications prese4nted are then each applied to a specific kind of genetic diagnosis and the text concludes with a chapter devoted to population genetics.

The book provides a broad overview of the fundamental theory and applications used in the diagnosis of numerous genetic diseases. Each chapter has been written by leading professionals in the field and is intended to show how molecular biology( DNA or RNA technology) may be applied to a large set of genetic diagnoses. Comprehensive coverage of DNA applications and genetic diagnoses includes a chapter on population genetics essential reading for students taking courses in medical genetics, medicine and molecular biology

There is no single truth regarding the recognition and management of IBD. In this regards the old dictum "there is no disease but the patient" should be the golden rule. Nowadays, more complicated Crohn's disease cases at relatively young ages are not unusual. Various clinical and extraintestinal manifestations have been seen rarely until now. The evolution of the therapeutic armamentarium is now a double-edged sword since "more drugs" may mean "more side-effects, less compliance and a more critical attitude of health authorities towards the cost of treatment". Education of the patient and the family, creation of empathy and a positive rapport with the patient and a careful analysis of confounding/contributing factors to the disease behaviour are essential elements of optimal therapy of IBD patients. This book contains the proceedings of Falk Symposium 159, entitled IBD 2007 -- Achievements in Research and Clinical Practice, held in Istanbul, Turkey, on May 4--5, 2007, where opinion leaders with worldwide reputations discuss IBD and related issues in a less well-known part of the world with respect to prevalence, disease behaviour and patient characteristics, as well as the difficulties faced in differential diagnosis and management.

Microalbuminuria, the abnormal urinary excretion of albumin, is recognized as an important independent marker of both renal and cardiovascular disease, particularly in diabetes mellitus. This volume is the only comprehensive and up-to-date review of the relevance of microalbuminuria to health and disease. It covers the pathophysiology and epidemiology of microalbuminuria and the methodology of laboratory assessment, and discusses the nonspecific nature of microalbuminuria in less well-recognized clinical situations. This is the first book to deal in detail with the treatment of microalbuminuria in both diabetic and nondiabetic subjects. This volume will be an essential source of reference and a guide to clinical practice for diabetologists, endocrinologists, cardiologists, renal physicians, and clinical biochemists.

This issue of Foot and Ankle Clinics, guest edited by Dr. Cesar de Cesar Netto, will discuss Controversies in managing the flatfoot deformity. This issue is one of four selected each year by long-time series Consulting Editor, Dr. Mark Myerson. Topics in this issue will include: What are the updates on epidemiology, Is advanced imaging a must, Tendon transfer vs. Allograft Reconstruction, Calcaneal osteotomies, The importance of the Medial Column, Osteotomies and stabilization, Lateral Column Lengthening, The role of arthroereisis in the adult patient, Management of Muscle and Tendon Balance in the Collapsing Foot, Spring Ligament and Deltoid Instability, Isolated subtalar joint fusion, and complex hindfoot deformity, among others.

The Understanding the Prostate chart is an overview of a component of the male reproductive system. Zones of the prostate are shown, along with a diagram of a digital rectal exam. Additional graphics and text describe prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer. Heavy cover stock with protective varnish for durability.

The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions.

* Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules * Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research * Offers step-by-step lab instructions, including necessary equipment, from a global research community

Cessation of tobacco use is the need of the hour given that it is the single largest cause of disease and premature death in the world. This book covers epidemiology and risks, user classification, nicotine replacement therapy, pharmacological aids, behavioral modification and patient counseling techniques, along with personalized action plan development. Key Features Covers all aspect of tobacco cessation. Provides guidance on differential diagnosis and includes useful decision-making flowcharts. Provides step-by-step guidance to counsel tobacco users in routine clinical practice. Discusses the process of setting up a cessation centre. Facilitates in-depth understanding of the subject through case studies at the end of each chapter

Integrates the various disciplines of the science of health disparities in one comprehensive volume The Science of Health Disparities Research is an indispensable source of up-to-date information on clinical and translational health disparities science. Building upon the advances in health disparities research over the past decade, this authoritative volume informs policies and practices addressing the diseases, disorders, and gaps in health outcomes that are more prevalent in minority populations and socially disadvantaged communities. Contributions by recognized scholars and leaders in the field--featuring contemporary research, conceptual models, and a broad range of scientific perspectives--provide an interdisciplinary approach to reducing inequalities in population health, encouraging community engagement in the research process, and promoting social justice. In-depth chapters help readers better understand the specifics of minority health and health disparities while demonstrating the importance of advancing theory, refining measurement, improving investigative methods, and diversifying scientific research. In 26 chapters, the book examines topics including the etiology of health disparities research, the determinants of population health, research ethics, and research in African American, Asians, Latino, American Indian, and other vulnerable populations. Providing a unified framework on the principles and applications of the science of health disparities research, this important volume: Defines the field of health disparities science and suggests new directions in scholarship and research Explains basic definitions, principles, and concepts for identifying, understanding and addressing health disparities Provides guidance on both conducting health disparities research and translating the results Examines how social, historical and contemporary injustices may influence the health of racial and ethnic minorities Illustrates the increasing national and global importance of addressing health disparities Discusses population health training, capacity-building, and the transdisciplinary tools needed to advance health equity A significant contribution to the field, The Science of Health Disparities Research is an essential resource for students and basic and clinical researchers in genetics, population genetics, and public health, health care policymakers, and epidemiologists, medical students, and clinicians, particularly those working with minority, vulnerable, or underserved populations.

Incorporates mixed-effects modeling techniques for more powerful and efficient methods
This book presents current and effective nonparametric regression techniques for longitudinal data analysis and systematically investigates the incorporation of mixed-effects modeling techniques into various nonparametric regression models. The authors emphasize modeling ideas and inference methodologies, although some theoretical results for the justification of the proposed methods are presented.
With its logical structure and organization, beginning with basic principles, the text develops the foundation needed to master advanced principles and applications. Following a brief overview, data examples from biomedical research studies are presented and point to the need for nonparametric regression analysis approaches. Next, the authors review mixed-effects models and nonparametric regression models, which are the two key building blocks of the proposed modeling techniques.
The core section of the book consists of four chapters dedicated to the major nonparametric regression methods: local polynomial, regression spline, smoothing spline, and penalized spline. The next two chapters extend these modeling techniques to semiparametric and time varying coefficient models for longitudinal data analysis. The final chapter examines discrete longitudinal data modeling and analysis.
Each chapter concludes with a summary that highlights key points and also provides bibliographic notes that point to additional sources for further study. Examples of data analysis from biomedical research are used to illustrate the methodologies contained throughout the book. Technical proofs are presented in separate appendices.
With its focus on solving problems, this is an excellent textbook for upper-level undergraduate and graduate courses in longitudinal data analysis. It is also recommended as a reference for biostatisticians and other theoretical and applied research statisticians with an interest in longitudinal data analysis. Not only do readers gain an understanding of the principles of various nonparametric regression methods, but they also gain a practical understanding of how to use the methods to tackle real-world problems.

This unique and engaging open access title provides a compelling and ground-breaking account of the patient safety movement in the United States, told from the perspective of one of its most prominent leaders, and arguably the movement's founder, Lucian L. Leape, MD. Covering the growth of the field from the late 1980s to 2015, Dr. Leape details the developments, actors, organizations, research, and policy-making activities that marked the evolution and major advances of patient safety in this time span. In addition, and perhaps most importantly, this book not only comprehensively details how and why human and systems errors too often occur in the process of providing health care, it also promotes an in-depth understanding of the principles and practices of patient safety, including how they were influenced by today's modern safety sciences and systems theory and design. Indeed, the book emphasizes how the growing awareness of systems-design thinking and the self-education and commitment to improving patient safety, by not only Dr. Leape but a wide range of other clinicians and health executives from both the private and public sectors, all converged to drive forward the patient safety movement in the US. Making Healthcare Safe is divided into four parts: I. In the Beginning describes the research and theory that defined patient safety and the early initiatives to enhance it. II. Institutional Responses tells the stories of the efforts of the major organizations that began to apply the new concepts and make patient safety a reality. Most of these stories have not been previously told, so this account becomes their histories as well. III. Getting to Work provides in-depth analyses of four key issues that cut across disciplinary lines impacting patient safety which required special attention. IV. Creating a Culture of Safety looks to the future, marshalling the best thinking about what it will take to achieve the safe care we all deserve. Captivatingly written with an "insider's" tone and a major contribution to the clinical literature, this title will be of immense value to health care professionals, to students in a range of academic disciplines, to medical trainees, to health administrators, to policymakers and even to lay readers with an interest in patient safety and in the critical quest to create safe care.

Jones & Bartlett Learning's Pocket Guide for Medical Assisting provides the essential information you need to make the transition from the classroom to the clinic as smooth and as stress-free as possible. The streamlined, quick-reference format allows you to easily find key information to carry out clinical, administrative, and laboratory duties. It keeps all the essential information at hand and organized for easy review and is the ideal procedure manual every medical assistant needs for the practice setting.

Well over two million medical students, doctors and other health professionals around the globe have owned a copy of Davidson's Principles and Practice of Medicine since it was first published over 70 years ago. Now in its 24th Edition, this thoroughly updated textbook describes the pathophysiology and clinical features of the most frequently encountered conditions in the major specialties of adult medicine, and explains how to recognise, investigate, diagnose and manage them. Taking its origins from Sir Stanley Davidson's much-admired lecture notes, Davidson's has endured because it keeps pace with how modern medicine is taught and provides a wealth of trusted information in an easy-to-read, concise and beautifully illustrated format. Key features: Part 1 'Fundamentals of Medicine' - provides an account of the principles of genetics, immunology, infectious diseases, population health, oncology and pain management, along with a discussion of the core principles behind clinical decision-making and good prescribing. Part 2 'Emergency and Critical Care Medicine' - covers medical emergencies in poisoning, envenomation and medicine in austere environments, as well as common presentations in acute medicine and the recognition and management of the critically ill. Part 3 'Clinical Medicine'- covers the major medical specialties, each thoroughly revised and brought fully up to date. A new section on COVID-19 has been added and the impact of this infection is described throughout the book. Clinical Examination overviews - extended and updated to summarise the main elements for each system. Presenting Problems sections - provide a clear pathway for the assessment of and approach to the most common complaints in each specialty. Practice Point summaries - detail the practical skills that medical students and junior doctors must acquire. Emergency boxes - emphasise the core knowledge needed to manage acutely ill patients. In Old Age, In Pregnancy and In Adolescence boxes - highlight differences in the practice of medicine in these patient groups, and illustrate the interfaces between medical, obstetric and paediatric services. The text is extensively illustrated - with over 1000 diagrams, clinical photographs, and radiology and pathology images. The global perspective is enhanced by an International Advisory Board of experts from 11 countries and by leading authors from around the world. The complete, downloadable eBook version is included with your (print copy) purchase - for easy access on your portable device, anytime, anywhere! Now enhanced with: NEW interactive self-assessment material - over 150 Questions and Answers test your understanding of chapter key points and aid efficient exam preparation Davidson's will serve readers everywhere as a core text that integrates medical science with clinical medicine, conveying key knowledge and practical advice in a highly accessible and readable format. REVIEWS Beautifully constructed with superb clarity of style - Davidson's continues to provide for students, doctors and other health professionals a sound basis for the practice of medicine. Royal Society of Medicine and Society of Authors Medical Book Awards This book comes through where others fail: an excellent textbook, easy to read and superb value. British Medical Journal

The pathophysiology of sepsis can be regarded as a series of steps, beginning with the invasion of normally sterile tissue by microbes and the elaboration of various pro-inflammatory mediators. The final common pathway is often the development of the multiple organ dysfunction syndrome (MODS). Whereas a great deal has been learned during the past quarter century about the inflammatory processes associated with sepsis (and other related conditions, such as ischemia/reperfusion injury), our understanding is far less developed with respect to the pathophysiological events that lead to organ dysfunction under these conditions. Nevertheless, efforts by both clinical and laboratory scientists are leading to new knowledge in this area. The chapters in this volume provide a state-of-the-art overview of many aspects of the pathophysiology of organ dysfunction in critical illness.

Welcome to the Clinics Collections! We have taken a multidisciplinary approach and selected the most recent and vital articles throughout all of our Clinics series and combined them into a single source on Precision Medicine. Articles are featured from multiple Clinics to highlight the range of specialties covering this major medical issue. Such information is essential to successful interdisciplinary teamwork and patient care. The articles within, written from different medical perspectives, will give deeper insight into how each specialty cares for its patients. The challenge in Precision Medicine involves specialized treatment planning with the ultimate goal of successful patient outcomes. The articles selected provide a unique entry into sharing best concepts for the entire medical team to learn and implement. Areas of focus include breast cancer, lung cancer, melanoma, arthritis, sleep medicine, and pediatric oncology. Each article begins with keywords and key points for immediate access to the most critical information. Articles are presented in an easy-to-digest and concisely worded format.

This issue of Medical Clinics, guest edited by Dr. Robert A. Smith and Dr. Kevin Oeffinger, is devoted to Cancer Screening and Prevention. Articles in this important issue cover the development of cancer screening guidelines, implementing cancer screening in the clinical setting, and screening for colorectal, lung, cervical, prostate, skin, and ovarian cancer.

Das einzige evidenzbasierte Fachbuch zu viralen Lebererkrankungen, das sich ausschliesslich mit schwierigen Situationen beschaftigt, mit denen sich klinische Hepatologen und das medizinische Personal immer wieder auseinandersetzen mussen. Auch wenn die virale Hepatitis weltweit auf dem Vormarsch ist und eine wachsende Bedrohung im Gesundheitswesen darstellt, ist fur die Weltgesundheitsorganisation (WHO) die Ausrottung von Hepatitisinfektionen mittelfristig ein erreichbares Ziel. Wirksame Medikamente und Therapien stehen zwar zur Verfugung, das medizinische Personal, das Patienten mit viraler Hepatitis betreut, steht aber immer wieder vor der Herausforderung, in der heutigen medizinischen Literatur Antworten auf spezifische Fragen zu finden. Die 2. Auflage von Clinical Dilemmas in Viral Liver Disease ist ein evidenzbasierter Leitfaden fur medizinisches Personal in den Bereichen Diagnose, Behandlung und Management von Patienten mit viralen Lebererkrankungen. Das komplett uberarbeitete Referenzwerk zeigt neue Behandlungs- und Diagnoseansatze, die beitragen, die WHO-Ziele zu erreichen. Die einzelnen Kapitel untersuchen klar umrissene Themenfelder, gehen auf klinische Fragestellungen und Schwierigkeiten ein, vor denen Mediziner tagtaglich stehen. International renommierte Forscher und Kliniker beschaftigen sich in ihren Beitragen mit klinischen Fragen und Problemen, die anderen Standardwerken und Online-Datensammlungen vielfach unberucksichtigt bleiben. Dieses einzigartige Fachbuch bietet praktische Hilfestellung zu den spezifischen Herausforderungen und Kernfragen bei der Behandlung von Patienten mit viralen Lebererkrankungen: - Bietet praxisorientierte, evidenzbasierte Hilfestellung zu aktuellen und kontroversen Themen. - Beschaftigt sich mit Fragestellungen, die im Klinikalltag auftreten und bislang wenig untersucht wurden. - Eroertert die Herausforderungen rund um globale Programme zur Ausrottung von Hepatitisinfektionen. - Folgt einem zielgerichteten Ansatz und greift dabei auf aktuelle Literatur und Expertenmeinungen zuruck. Die 2. Auflage von Clinical Dilemmas in Viral Liver Disease ist ein Muss fur Hepatologen, Gastroenterologen, Transplantationschirurgen, Virologen und medizinisches Fachpersonal, das Patienten mit Lebererkrankungen betreut.

Proceedings of the November 1994 meeting. The 59 contributions cover glucose recognition, the role for K (ATP) channels, intracellular messengers, modulation of islet release, beta-cell metabolism and Ca2+, beta-cell heterogeneity: building a homogeneous response from a heterogeneous population, ISS