Atrial fibrillation is the most common sustained arrhythmia in humans. An incredible worldwide effort from physicians, scientists and industry over the last decade has brought forth new insights and therapeutic tools. We are fortunate to have achieved a level of understanding about this complex disease that we can indeed cure some patients. While we proceed at full speed ahead looking for cures for the rest, we have taken this opportunity in the Medical Clinics of North America to reflect on how much we have learned and on the task that lies ahead. This issue opens with a historical perspective, discusses many of the clinical issues in the management of atrial fibrillation, such as cardioversion, anticoagulation and ablation, and concludes with the current guidelines for treatment and a view of the future.

Intended for clinicians & students at all levels, this volume offers a detailed guide to the clinical trial process. It aims to help health workers discuss the pros and cons of participation with patients.

Now in its fifth edition, the Oxford Handbook of Emergency Medicine is the essential rapid-reference guide to emergency medicine for everyone from junior doctors to specialist registrars, nurse practitioners, and paramedics. New and improved, the Handbook has been thoroughly revised throughout, with 100 extra illustrations and the latest guidelines and treatment advice, completely overhauled chapters on Medicine, Obstetrics and Gynaecology, and Paediatric emergencies, and new topics on treatment escalation, end-of-life care, and sepsis. Clear and concise, extensively updated, and packed with a host of new X-rays to aid identification and treatment, this Handbook has everything you need to thrive in the demanding world of emergency medicine today.

Now in its sixth edition, this guide sets out international and standard practice and is an invaluable reference for medical and scientific editors and authors. Scholarly journals often quote this booklet as a guide in their instructions to authors. An invaluable reference for editors and authors Includes fully updated sections on metrication and SI units, symbols and nomenclature, layout of references and proof correction

Evolutionary Medicine is based upon the view that many contemporary social, psychological, and physical illnesses are related to an incompatability between current human lifestyles and environments and the conditions under which human biology developed. This book, featuring contributions from many of the leading workers in this devloping area, provides a good introduction and overview to this emerging field.

Drawing on interdisciplinary, cross-national perspectives, this open access book contributes to the development of a coherent scientific discourse on social exclusion of older people. The book considers five domains of exclusion (services; economic; social relations; civic and socio-cultural; and community and spatial domains), with three chapters dedicated to analysing different dimensions of each exclusion domain. The book also examines the interrelationships between different forms of exclusion, and how outcomes and processes of different kinds of exclusion can be related to one another. In doing so, major cross-cutting themes, such as rights and identity, inclusive service infrastructures, and displacement of marginalised older adult groups, are considered. Finally, in a series of chapters written by international policy stakeholders and policy researchers, the book analyses key policies relevant to social exclusion and older people, including debates linked to sustainable development, EU policy and social rights, welfare and pensions systems, and planning and development. The book's approach helps to illuminate the comprehensive multidimensionality of social exclusion, and provides insight into the relative nature of disadvantage in later life. With 77 contributors working across 28 nations, the book presents a forward-looking research agenda for social exclusion amongst older people, and will be an important resource for students, researchers and policy stakeholders working on ageing.

At the present time, 430 drugs are known to cause respiratory injury. This represents an increase of almost 200 in the last ten years, and the number is still increasing. This comprehensive, definitive reference work, with an outstanding range of international expert contributors and two of the world's leading editors, provides an essential reference for the practising respiratory physician. Key features: The text builds upon basics with a review of basic sciences. The book covers imaging, varied drug-induced interstitial lung disease including pulmonary edema and diffuse alveolar hemorrhage, acute respiratory failure, pleural involvement and upper to lower airway disease A wide range of diseases are detailed from chemotherapy and radiation to biologic-induced lung disease, drug misuse, and special groups such as recipients of stem cell and solid organ transplants. A range of world class contributions from key opinion leaders. This book provides essential information for recognizing and managing drug-induced respiratory disease for all pulmonologists and respiratory care physicians. It will be of great interest to: critical care medicine specialists, hematologists, oncologists, cardiologists, allergists, rheumatologists, neurologists, internists, blood-bank specialists, pathologists and primary care physicians.

Here's an extremely handy pocket reference to assist the student, resident, house officer, and busy hospitalist address issues related to the 20 most common disorders seen in the inpatient setting. This brief, small-sized handbook offers you evidence-based information presented in an easy to reference, consistently presented outline and table format. Problem based for quick solutions in diagnosis and therapy in the limited timeframe typical of seeing patients on the wards. Provides a brief presentation of 20 most common inpatient disorders. Provides reliabile diagnosis and treatment options with evidence based recommodations. Handy, pocket book that takes up minimal pocket real estate.

Fertility and Pregnancy: An Epidemiologic Perspective, is a lively overview of human reproduction: how it works, and what causes it to go wrong. Weaving together history, biology, obstetrics, pediatrics, demography, infectious diseases, molecular genetics, and evolutionary biology, Allen Wilcox brings a fresh coherence to the epidemiologic study of reproduction and pregnancy. Along the way, he provides entertaining anecdotes, superb graphs, odd tidbits and occasional humor that bring the topic to life.
The book is divided into two sections. The first lays the foundations - the basic principles of reproductive physiology, demography, infectious diseases, and genetics as they apply to human reproduction. The second part deals with the endpoints of reproductive epidemiology - a spectrum ranging from infertility and fetal loss to birth defects and the delayed effects of fetal exposures. The book closes with a discussion of unsolved problems, suggesting possible research projects for a new generation of epidemiologists. An extensive glossary makes this a valuable reference as well as an enjoyable read.

"Medicine and Surgery" is an exciting new book that contains the core information needed by medical students in the run up to exams.

This is the only book available that covers both medicine and surgery.

It encompasses all of the major systems and core subjects
Every condition is discussed under the key headings of definition, epidemiology, aetiology, pathophysiology, clinical features, investigations, management and prognosis
The content follows a very consistent and familiar style, so that information is easily accessible, digestible and memorable
Each chapter opens with an overview of clinical method before discussing the most common conditions relevant to that speciality

"Medicine and Surgery: A Concise Textbook" is written specifically for medical students as essential revision preparation, for junior doctors as a refresher on the wards and for other allied health professionals who want a quick reminder of key facts and data.

Reviews

"I like the way the book goes through each disease using the same system of definition, aetiology etc. This makes it easier to learn....The content is exactly what the undergraduate brain needs"

Final year student, University of Oxford

"Vital Notes on Accountability" is a concise, accessible guide which provides students and newly qualified staff with an understanding of key issues in professional practice. Nurses are accountable for their own practice and require a thorough understanding of their core responsibilities which underpin everyday practice in the health service today.

This introductory text in the 'Vital Notes for Nurses' series sets out a framework for accountability which consists of four 'pillars' - legal, ethical, employment and professional accountability - against which clinical issues can be considered.

* Presents legal, ethical, employment and professional issues in an accessible way
* Explores accountability, professional regulation, sources of funding and treatment in the health service
* Examines complaints, human rights, negligence, consent, and confidentiality
* Explores further applications in accountability
* Each chapter includes learning objectives, scenarios and case studies

This text promotes the view that the clinical education process offers both clinical educators and students opportunities for personal and professional development. It guides the reader through the clinical education process, from pre--placement preparation to assessment of learning that supports and encourages personal and professional development. Included are resources for supporting the clinical education process, such as checklists, case studies and proformas, and vignettes illustrate the richness of studentsa and clinical educatorsa learning experiences.

Addressing issues at the forefront of interest for the Clinical Trial Materials Professional (CTMP), this Second Edition highlights the most critical concepts related to the planning, manufacturing, packaging, labeling, distribution, reconciliation, and quality and regulatory control of clinical trial materials. It offers authoritative chapters by esteemed researchers and consultants in industry on the current and evolving state of clinical supplies operations. Tracking emerging trends and the development of new technologies, this Second Edition helps the CTMP operate effectively in the international sphere and reviews regulatory processes for drug approvals in the United States and Europe.

Here are 101* of the best ideas to make the most effective use of your time on the ward. Over 250 contributors, including students, doctors, nurses, pharmacists, and therapists from 18 countries, help make you the finest doctor you can be

Pocket-sized for 'dipping into' during a spare moment or a couple of hours on the ward, this short guide is ideal for medical students on rotation or junior doctors who wish to boost learning and motivation.

*There are actually 100 ideas. Now it's your turn to develop tip 101 Submit your ideas to www.101things.org

A cluster randomization trial is one in which intact social units, or clusters of individuals, are randomized to different intervention groups. Trials randomizing clusters have become particularly widespread in the evaluation of non-therapeutic interventions, including lifestyle modification, educational programmes and innovations in the provision of health care. The increasing popularity of this design among health researchers over the past two decades has led to an extensive body of methodology on the subject. This is the first book to present a systematic and united treatment of this topic; it contains distinctive chapters on the history of cluster randomized trials, ethical issues and reporting guidelines.

Offering a unified resource for both clinicians and pharmacists, A Medication Guide to Internal Medicine Tests and Procedures provides concise, focused answers to common medication questions before, during, and after internal medicine tests and procedures. Co-authored by experienced physicians and clinical pharmacists, this unique, time-saving reference brings together essential information for healthcare providers and students in a convenient, highly templated, pocket-sized book. Addresses the many medication questions surrounding 54 of the most commonly used tests and procedures. Ensures proper peri-procedural management by addressing what medications need to be administered or held ahead of a specific test. Provides foundational guidance on the diagnostic process, anticoagulation and glycemic management in the periprocedural period, and anesthesia, followed by highly templated chapters arranged alphabetically by procedure name. Includes brief descriptions of tests, how they are performed, and common findings. Helps readers avoid interference with tests and unnecessary adverse effects, optimizing patient outcomes. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Summarizing discussions from the Vancouver Orbital Symposium, this reference assembles recent perspectives from world renowned orbital specialists, pathologists, radiologists, and scientists to highlight advances and challenges in the diagnosis and management of orbital disease-covering recent aspects of orbital inflammatory and infectious disorders, issues in oncology, thyroid disease, and orbital vascular disorders, as well as topics concerning the future of imaging and orbital surgery.

In this book, we present a novel framework of high-tech modern medicine. Patients going through major high-tech medical interventions, e.g. Advanced Heart Failure (AdHF) patients undergoing left ventricular assist device (LVAD) implantation and heart transplantation, must integrate scientific and technological advances into personal life, including strong emotional experiences unthinkable thirty years ago, novel to themselves and their caregivers and unknown to healthcare professionals. Our book provides a theoretical framework for the person-centered vision to "heal humankind by improving health, alleviating suffering and delivering acts of kindness, one person at a time", we develop the theoretical as well as practical concept of the "RelationalAct (RA) " as core concept to engage and participate in modern medicine.This book will be used as a recommended textbook for the following UCLA Fall 2014 course: Course Director: Professor Federica Raia / Co-Director: Professor Mario Deng Course Title: Educational Perspectives of Relational Practices in Modern Medicine Course Summary: This UCLA course systematically discusses Personhood & Body Concepts in the context of asymmetric Person/Person-relationships in High-Tech Modern Medicine and the diverse implications for building of theories of Relational Practice. Course Topics: Personhood/Body Concepts; Asymmetric Person/Person-relationships; Theories of Relational Practice

Analyzing ground-breaking research, this reference highlights the impact of sleep deprivation on the well-being of the individual and society-presenting current theories on the function of sleep, the effects of sleep deprivation on patients with medical and psychiatric conditions, as well as providing interpretative and methodological results in comparative studies of sleep deprivation.

This book helps to recognize the rights of refugees and provides a framework to identify and approach health needs, from basic elements like service mapping and initial interventions to more complex elements of ongoing healthcare and support and broader topics such as migration public health, migration policy and health systems. Beyond biomedical frameworks, it draws on socio-ecological models to inform assessments and integrated models of care to improve health and health equity. Set out in three comprehensive sections: public health theory (Part 1), applied public health (Part 2), and clinical approaches (Part 3), this book draws on multiple disciplines and insights from humanitarians, academics, policy experts, and clinicians from diverse contexts, with expertise in forced migration, to create an accessible reference tool to inform healthcare professionals' interactions with forcibly displaced individuals and populations in all contexts for both high and low resource countries. Apart from providing information across the spectrum of health issues, clinical specialties and global contexts, it discusses associated areas, including human rights and law, public health, medical anthropology and cultural awareness. Key Features: Bridges the gap between existing academic literature on refugee health and guidelines for health management in humanitarian emergencies Helps to develop an integrated approach to healthcare provision, allowing healthcare professionals and humanitarians to adapt their specialist knowledge for use in forced migration contexts and with refugees. Recognizes the complex and interconnected needs in displacement scenarios and identifies holistic and systems-based approaches. Covers public health theory, applied public health and clinical aspects of forced migration.

Attracting the attention of the medical community, exhaled breath condensate is a completely non-invasive method for sampling secretions from the airways. Analysis of exhaled breath condensate is potentially useful for monitoring airway inflammation and in pharmacological therapy. With its non-invasive nature, this method may be suitable for longitudinal studies even in children and in patients with lung severe disease. New Perspectives in Monitoring Lung Inflammation provides an introduction to the analysis of exhaled breath condensate for monitoring lung inflammation. The book presents current knowledge on the physicochemical properties of exhaled breath condensate and its formation in the airways and covers important aspects of the methodology. It details markers, and classes of markers, of airway inflammation in separate chapters and discusses the use of the technique in adults and children. The text also reviews the implications for drug development and future research. The volume concludes with an overview of lung inflammation focusing on basic and clinical pharmacology of important mediators. Presenting a comprehensive view of exhaled breath condensate, the text explains how this method could play a major role in the diagnosis and therapy of lung diseases, and may launch a new era in respiratory medicine.

Rutter's Child and Adolescent Psychiatry is the leading textbook in its field. Both interdisciplinary and international, it provides a coherent appraisal of the current state of the field to help researchers, trainees and practicing clinicians in their daily work. Integrating science and clinical practice, it is a comprehensive reference for all aspects of child and adolescent psychiatry. New to this full color edition are expanded coverage on classification, including the newly revised Diagnostic and Statistical Manual of Mental Disorders (DSM-5), and new chapters on systems neuroscience, relationship-based treatments, resilience, global psychiatry, and infant mental health. From an international team of expert editors and contributors, this sixth edition is essential reading for all professionals working and learning in the fields of child and adolescent mental health and developmental psychopathology as well as for clinicians working in primary care and pediatric settings. Michael Rutter has contributed a number of new chapters and a Foreword for this edition: "I greatly welcome this new edition as providing both a continuity with the past and a substantial new look." Professor Sir Michael Rutter, extract from Foreword. Reviews of previous editions: "This book is by far the best textbook of Child & Adolescent Psychiatry written to date." Dr Judith Rapoport, NIH "The editors and the authors are to be congratulated for providing us with such a high standard for a textbook on modern child psychiatry. I strongly recommend this book to every child psychiatrist who wants a reliable, up-to-date, comprehensive, informative and very useful textbook. To my mind this is the best book of its kind available today." Journal of Child Psychology and Psychiatry

This publication is concerned with the early stages of language acquisition and is designed for use by early childhood teachers, nursery nurses, special education teachers and others working with children experiencing difficulties in learning to talk. Procedures are described that can be used to assess a child' s current skills and plan activities to increase communicative competence.

The programme described is based on a developmental sequence that moves the early skills of joint attention, turn-taking and appropriate play to the more complex skills of asking and answering questions. Other issues discussed include sound development and intelligibility, the use of augmentative and alternative communication as stepping stones to speech, working with children and with families.

The second edition has an expanded focus on the place of communicative intentions in early language development.

A full-color case-based review of the essentials of pathophysiology covering all major organs and systems More than 130 case studies with Q&A The goal of this trusted text is to introduce you to clinical medicine by reviewing the pathophysiologic basis of 132 diseases (and associated signs and symptoms) commonly encountered in medical practice. The authors, all experts in their respective fields, have provided a concise review of relevant normal structure and function of each body system, followed by a description of the pathophysiologic mechanisms that underlie several common diseases related to that system. The accessible presentation features high-quality full-color illustrations, and numerous tables and diagrams. Each chapter of Pathophysiology of Disease concludes with a collection of case studies and questions designed to test your understanding of the pathophysiology of each clinical entity discussed. These case studies allow you to apply your knowledge to specific clinical situations. Detailed answers to each case study question are provided at the end of the book. This unique interweaving of physiological and pathological concepts will put you on the path toward thinking about signs and symptoms in terms of their pathophysiologic basis, giving you an understanding of the "why" behind illness and treatment. HERE ARE SOME OF THE MANY UPDATES AND ADDITIONS:*Twelve additional case studies, bringing the total to 132, one for each of the clinical entities discussed in the book's 24 chapters*More than 2/3 of the chapters are enhanced and refreshed by the input of new contributors*Totally revised chapter on neoplasia*New chapter sections on urticaria, spinocerebellar ataxia, idiopathic pulmonary fibrosis, and spondyloarthropathies*New tables summarizing adverse prognostic signs in acute pancreatitis, genetic syndromes associated with pancreatic cancer, and causes of end-stage renal disease*New diagnosis and etiologic classification of diabetes mellitus, and review of mechanisms of newest pharmacologic agents for its treatment*Updates on fine-needle aspiration biopsy of thyroid nodules, and thyroid disorders in pregnancy*Updated references throughout the book