Mesenchymal stem cells (MSCs), a type of adult stem cells, have attracted the attention of scientists and physicians alike due to their unique biological properties and potential for disease treatment. As stem cell research is complex and progressing rapidly, it is important that the experts in this field share their views and perspectives. This book, co-edited by leading global researchers, is divided into three major sections and covers a broad range of topics concerning MSCs during their transition from benchside to bedside. The book is intended for researchers and clinicians in the field of stem cells. Dr. Robert Chunhua Zhao, MD. Ph.D is Cheung Kong Professor of Stem Cell Biology, Professor of Cell Biology at the Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, China Director of Center for Tissue Engineering, PUMC Chief scientist of 973 program Regional Editor of Stem Cells and Development.

LEADERSHIP IN VETERINARY MEDICINE Leadership in Veterinary Medicine provides both theoretical and practical information for veterinary professionals who are contemplating leadership or currently facing day-to-day leadership challenges. This much-needed book introduces and explores key leadership concepts in the veterinary context whilst encouraging self-reflection through real-world scenarios. Each chapter outlines a particular leadership concept or issue and includes a topic summary, discussion questions, full references and further reading suggestions. This thought-provoking text: Explores the principal areas of leadership for both veterinary professionals and for those leading veterinary professionals Discusses various leadership styles, competencies, behaviours and perspectives Addresses topics such as leadership assessment, organisational dynamics, interpersonal communication, remote and virtual leadership, and collaboration skills Assists readers in developing strategy, leading change, creating effective teams and improving staff engagement Includes practical cases and examples highlighting challenges in veterinary leadership Leadership in Veterinary Medicine is a must-read for all veterinary professionals in leadership posts, for those aspiring to be leaders and for instructors in veterinary schools and veterinary nursing training organisations.

Selected as a Doody's Core Title for 2022! Designed for busy clinicians struggling to fit the critical issue of nutrition into their routine patient encounters, Nutrition in Clinical Practice translates the robust evidence base underlying nutrition in health and disease into actionable, evidence-based clinical guidance on a comprehensive array of nutrition topics. Authoritative, thoroughly referenced, and fully updated, the revised 4th edition covers the full scope of nutrition applications in clinical practice, spanning health promotion, risk factor modification, prevention, chronic disease management, and weight control - with a special emphasis on providing concisely summarized action steps within the clinical workflow. Edited by Dr. David L. Katz (a world-renowned expert in nutrition, preventive medicine, and lifestyle medicine) along with Drs. Kofi D. Essel, Rachel S.C. Friedman, Shivam Joshi, Joshua Levitt, and Ming-Chin Yeh, Nutrition in Clinical Practice is a must-have resource for practicing clinicians who want to provide well-informed, compassionate, and effective nutritional counseling to patients. Features short, easily digestible chapters with updated references. Includes comprehensive updates throughout, as well as a newly expanded section on Contemporary Topics in Nutrition. Covers key topics such as the ketogenic diet, intermittent fasting, ultraprocessed food, and strength of evidence assessment in nutrition. Provides data from recent nutritional studies, helpful nutrition data tables, clinically relevant formulas, and patient-specific meal planners. Addresses special topics such as pregnancy and lactation, pediatric nutrition, athletic performance and sports nutrition, health effects of specific foods, plant-based diets, and many more. Features expert contributions from authors with diverse expertise and practical experience in medical education, clinical practice, and preventive medicine. , Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. ,

New technologies in 3D printing offer innovative capabilities in surgery, from planning complex operations through to educational purposes and providing alternatives to traditional training with more cost-effective outcomes. This hot topic title synthesizes the most up-to-date information on 3D printing and its application into surgical specialties including, hebatobilliary and pancreatic surgery, vascular surgery, orthopedic surgery, obstetrics and gynecology, cardiovascular and thoracic surgery, and more. Discusses challenges and opportunities of 3D printing across surgical sub-specialties. Covers 3D printing and its application in major surgical specialties, as well as dentistry, transplantation, global surgery, and diagnostic and interventional radiology. Consolidates today's available information on this burgeoning topic into a single convenient resource.

The story of mankind's struggle against polio is compelling, exciting and full of twists and pardoxes. One of the grand challenges of modern medicine, it was a battleground between good and bad science. Gareth Williams takes an original view of the journey to understanding and defeating polio.

The scope for improving health care using stem cell therapies is thrilling, but has considerable technical challenges and methodological constraints that need to be addressed. Keeping with the tradition of Humana Press to bring these developments to the forefront in a timely manner, this book presents scientific advances in stem cell methods for a wider use by novice and expert scientists, through the series of Methods in Molecular Biology.

MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. More than 400 pictures of different typical and atypical MS lesions are demonstrated in this atlas. Each image has a teaching point. New diagnostic criteria and differential diagnosis are discussed.

A concise, easy-to-read source of essential tips and skills for writing research papers and career management In order to be truly successful in the biomedical professions, one must have excellent communication skills and networking abilities. Of equal importance is the possession of sufficient clinical knowledge, as well as a proficiency in conducting research and writing scientific papers. This unique and important book provides medical students and residents with the most commonly encountered topics in the academic and professional lifestyle, teaching them all of the practical nuances that are often only learned through experience. Written by a team of experienced professionals to help guide younger researchers, A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing features ten sections composed of seventy-four chapters that cover: qualities of research scientists; career satisfaction and its determinants; publishing in academic medicine; assessing a researcher's scientific productivity and scholarly impact; manners in academics; communication skills; essence of collaborative research; dealing with manipulative people; writing and scientific misconduct: ethical and legal aspects; plagiarism; research regulations, proposals, grants, and practice; publication and resources; tips on writing every type of paper and report; and much more. An easy-to-read source of essential tips and skills for scientific research Emphasizes good communication skills, sound clinical judgment, knowledge of research methodology, and good writing skills Offers comprehensive guidelines that address every aspect of the medical student/resident academic and professional lifestyle Combines elements of a career-management guide and publication guide in one comprehensive reference source Includes selected personal stories by great researchers, fascinating writers, inspiring mentors, and extraordinary clinicians/scientists A Guide to the Scientific Career: Virtues, Communication, Research and Academic Writing is an excellent interdisciplinary text that will appeal to all medical students and scientists who seek to improve their writing and communication skills in order to make the most of their chosen career.

Over the years, interventional radiology has developed many effective and less invasive procedures. As the number and types of interven tions increase, radiologists are becoming more and more involved in clinical patient care. This includes pre-interventional patient workup, sophisticated medical therapy and monitoring during interventions, regular inpatient rounds and complete follow-up management. Therefore interventional radiologists are faced with a broad spectrum of clinical and pharmacological questions. Adjunctive medical therapy should increase the patient's comfort, should improve the success rates, and should further reduce the risks of the procedures. In order to fulfill our responsibility to the patients, a profound knowledge of certain drugs is indispensable. This in cludes, for example, sedatives, analgesics, cardiovascular drugs and agents to prevent infections, thromboembolic complications or restenoses. Moreover, a good monitoring system during complex procedures will increase the safety of radiological interventions. These topics and several more have been presented and discussed during an international symposium in Basel, Switzerland, in January 1992. It is the benefit of the authors, that all these results could be published shortly after the event. Connected with our thanks to all the co-workers the editors hope to find this publication assisting an increasing number of safe interventions.

Medical care of the elderly today challenges the practitioner to break away from narrow diagnostic labelling and view the whole picture of disease in old age. In an excellent problem-oriented approach, Geriatric Medicine offers a complete overview for practitioners. The main portion of the text deals with the common diseases of old age; important aspects such as physiology, demography, and health care delivery are discussed in separate chapters. Social and legal aspects in the major English-speaking countries receive adequate attention. All of the contributors have at some time been connected with the University Department of Geriatric Medicine in Cardiff and attest to a positive and dynamic approach in geriatric medicine, an approach that has international validity and relevance.

Practicing Patient Safety in Psychiatry covers all problematic aspects of care delivery in an easy-to-read format. Both portable and practical, this easily referenced guide book is designed for psychiatric residents and clinicals looking to improve their understanding of critical care. Featuring a wide variety of case-studiy examples and take-home points, this book is an essential introduction of patient safety for practitioners looking to deliver the highest quality of care in both inpatient and outpatient environments. Dr. Geetha Jayaram has been the Physician Advisor for the department of Psychiatry at Johns Hopkins Hospital for 21 years, and the Chair Of the International Patient Safety committee for the American Psychiatric Association. Dr. Jayaram is an outstanding clinician who has thought patient safety to residents and faculty for two dedcades. She is a pioneer in the field of psychiatric pateint safety, and has been invited to teach safety both nationally and internationally for many years.

The history taking and communication skill stations are amongst the most difficult postgraduate examinations, where candidates more commonly fail due to an inability to communicate properly with the patient, rather than due to lack of knowledge. Authored by experienced postgraduate examiners, this book offers students a wealth of real-life scenarios in multi-conversational styles, using a seven-step approach to help them understand the questions and provide clear and succinct answers. The scenarios are similar to those most frequently encountered in examinations and the model answers are in a typical style expected between doctor and patient, also taking into account candidates for whom English may not be their first language. The comprehensive text is enhanced by illustrations and figures to assist learning and will be useful not only to candidates preparing for postgraduate clinical examinations, but also to undergraduate students. Key points Provides real-life, conversational-style scenarios between doctor and patient to help students prepare for postgraduate history taking and communication skill examinations Uses a seven-step approach to help postgraduates understand questions and provide clear and succinct answers Scenarios typical of those used in examinations Authored by experienced postgraduate examiners

Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed investigation of the complex set of intracellular interactions contributing to organ-selective actions of steroids and steroid-like compounds such as vitamin D. In this volume leading experts address basic molecular mechanisms of tissue specificity and related issue, with the goal of attaining a better understanding of the underlying mechanisms of organ selective actions of steroids. Discussed is the extent to which tissue specificity might selectively be modified by chemical modification of the hormones and how this may be applied towards improved therapies by taking advantage of tissue selectivity.

The metabolic syndrome is a common syndrome affecting about 20 % of the adult population in Europe, and probably the prevalence is of the same magnitude in other industrialised countries worldwide. It is mainly caused by western lifestyle resulting in abdominal obesity, but also a genetic predisposition plays a role. This syndrome, which is linked to leisure lifestyle and overeating/obesity, can develop into type 2 diabetes, cardiovascular disease and cancer. Therefore, proper treatment and prevention are heavily needed. This book discusses lifestyle intervention and treatment, specifically with pharmacological compounds, in order to formulate a strategy for treating the metabolic syndrome in the daily clinic.

This work by two accomplished Polish researchers provides medical technicians and researchers alike with detailed descriptions of up-to-date methods used for computer processing and interpretation of medical images. The broad scope of the book takes in images acquisition, storing with compression, processing, analysis, recognition and also its automatic understanding. The introduction provides a general overview of the computer vision methods designed for medical images.

Intensive care is a rapidly changing area of medicine, and after four years from the 2nd edition the volume editors and authors have deemed necessary to update it. In the recent years, in fact, five new randomised controlled trials and five new meta-analyses demonstrate that selective decontamination of the digestive tract [SDD] is an antimicrobial prophylaxis to prevent severe infections of not only lower airways but also of blood. Additionally, SDD has been shown to reduce inflammation including multiple organ failure and mortality. An intriguing observation is the evidence that SDD using parenteral and enteral antimicrobials reduces rather than increases antimicrobial resistance. Moreover, a new chapter on microcirculation had been added. The volume will be an invaluable tool for all those requiring in depth knowledge in the ever expanding field of infection control.

The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods. The purpose of this workshop was to discuss and overview multiple applications and emerging technologies in the area of diagnostic imaging including its fundamental capabilities in preclinical research, the opportunities for medical care, and the options involving therapeutic concepts. The book provides the reader with state-of-the-art information on the different aspects of diagnostic imaging, illuminating new developments in molecular biology, imaging agents and molecular probe design, and therapeutic techniques.

RevMED 300 SBAs in Clinical Specialties is a book of 300 single best answer questions covering a range of topics in paediatrics, obstetrics and gynaecology and psychiatry. These topics are the focus of 4th or 5th Year examinations in most medical school curriculums and have usually been separated from topics in general medicine and surgery.Question books are an exceptionally useful resource for medical students preparing for their clinical exams. RevMED 300 SBAs in Clinical Specialties is written by students who have recently sat clinical examinations at medical school and is designed to be student-friendly with detailed explanations and flow charts summarising the most up-to-date guidelines. The questions have been edited by teaching fellows and registrars to ensure the topics covered provide students with a functional understanding of important concepts with the hope of aiding their future careers.

Perioperative Addiction addresses an issue that every anesthesiologist will encounter many times during the course of his or her career: the patient who arrives for operative care under the influence of legal or illegal drugs. The editors and contributors provide expert guidance on how to identify and manage the addicted patient, approaching the subject from the vantage points of the specific drug and of special patient populations. Features: * Guidance for spotting and managing addicted patients * All common and important drugs of addiction, from opioids, cocaine, club drugs, and alcohol, to tobacco, marijuana, nitrous oxide, inhalants, and propofol * Special populations, including pregnant women, pain patients, adolescents, older patients, and healthcare professionals * Fascinating overview of the long history of addiction * Genetic basis of addiction, and the range of pharmacological treatments for addiction

This book explores the pathophysiology, clinical assessment and management of the obese patient in the context of serious chronic disease, as well as the political and environmental aspects, including prevention. The book's approach of arriving at an exploration of these issues through the vehicle of assessing the controversies is unique and interesting, attempting to debunk the myths and explore the genuine science whilst demonstrating areas where healthy debate is rife.

In spring this year it will be 23 years since I began to study rotation technique as applied to radiology. In applying this technique to roentgenography the name Rotation Radiography was adopted publicly in 1946. Since then this study has revealed that the technique is valuable not only in diagnosis but also in radiotherapy, and the name Conformation Radiotherapy was publicly an nounced in 1960. Through these studies it became clear that it is possible to show the axial transverse cross section of the human body roentgenographically, which could be of great value medically, but it was realized that no detailed roentgenograms of the axial transverse cross section covering the whole of the normal human adult have been published so far. To prepare an atlas was therefore considered basic for the practical application of this method, since without it further developments of this type of roentgenography cannot be expected. Conse quently it was decided first to prepare the atlas. In addition, the clinical application of this method to the diagnostic and therapeutic field was described with brief notes on the essential features of the method."

1. Renal failure following circulatory shock develops because of per- sistent vasoconstriction which is just sufficient to prevent glomerular filtration. Hypoxia of renal tissue has not been demonstrated in surviving cases. 2. During the low-pressure phase in circulatory shock the remaining blood flow through the medullary regions washes out the osmotic gradient built up by the countercurrent system of Henle's loops, so that a concentrated urine cannot be formed. 3. During recovery from circulatory failure the osmotic gradient of the medullary region can only be built up if sufficient fluid from the glomerular filtrate reaches the countercurrent system. The greater the GF, the faster the gradient is built up. References 1. BoYLAN, J. W. , and E. AssHAUER: Unpublished data. -2. DEETJEN, P. , and K. KRAMER: Pfliigers Arch. Physiol. (G. ) (in press). - 3. KRAMER, K. , and K. ULLRICH: Pfliigers Arch. Physiol. (G. ) 267,251 (1958). -4. KRA- MER, K. , K. THURAU and P. DEETJEN: Pfliigers Arch. Physiol. (G. ) 270, 251 (1960). - 5. KRAMER, K. , and P. DEETJEN: Pfliigers Arch. Physiol. (G. ) 271, 782 (1960). -6. KRAMER, K. , and P. DEETJEN: Unpublished data. - 7. KuHN, W. , and A. RAMEL: Helv. chim. acta 42,628 (1959). - 8. LASSEN, N. A. , 0. MuNcK and J. H. THAYSEN: Acta physiol. Scand. IJ1, 371 (1961). - 9. MUNCK, 0. : Renal Circulation in Acute Renal Failure. Oxford 1958.

Mapping BRICS Media is the first comprehensive and comparative study of the emerging media landscape in the world's most dynamic and fastest growing markets. This pioneering collection focuses on one of the key topics in contemporary international relations - the emergence of BRICS (Brazil, Russia, India, China and South Africa) - a grouping that includes some of the world's largest populations and fastest growing economies. The volume brings together leading scholars, mainly from the BRICS nations, to examine how the emergence of the BRICS media will impact on global media and communication. Contextualizing the rise of the BRICS nations within the broader shifts in global power relations, the chapters investigate the unprecedented growth of the BRICS media within a 'multi-polar' world, evaluating the media landscapes in the individual BRICS countries, their histories, and their journalism practices, as well as analyzing emerging inter-BRICS media relationships. Accessible and comprehensive, the book provides a critical guide to the complex debates about the impact of the 'rise of the rest' on the media globe and how far this poses a challenge to the Western-dominated world order and its media systems.

Firefighters are taught to battle flames. Police learn to respond quickly to 911 calls. So why are so few health officials prepared for public health crises? Updated to consider the COVID-19 pandemic, The Public Health Crisis Survival Guide is here to help. Whether it's an infectious disease outbreak, a scathing news report, or a sudden budget calamity, this book gives public health readers an honest and practical overview of what to do when things go wrong - not just to survive, but to lead and thrive in the most difficult circumstances. With examples drawn from history, recent headlines, and the author's own experience at the local, state, and federal levels, this book covers: * how to recognize, manage, and communicate in a crisis * how to pivot from managing a crisis to advocating for long-term policy change that can prevent the crisis from happening again * how to awaken a sense of crisis on a longstanding problem to generate momentum for change * taboo topics, including whether and how to apologize for mistakes Written by a voice of experience, practicality, good humor, and an eye toward the recent COVID-19 pandemic, The Public Health Crisis Survival Guide will be a source of enrichment and reassurance for the next generation of public health students and practitioners.