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Books > Medicine > Clinical & internal medicine > General

Essential Primary Care (Paperback): A Blythe Essential Primary Care (Paperback)
A Blythe
R1,379 Discovery Miles 13 790 Ships in 9 - 17 working days

Essential Primary Care aims to provide undergraduate students with a comprehensive overview of the clinical problems encountered in primary care. It covers the structure of primary care in the UK, disease prevention and the management of common and important clinical presentations from infancy to old age. Case studies are used in every chapter to illustrate key learning points. The book provides practical advice on how to consult with patients, make sense of their symptoms, explain things to them, and manage their problems. Essential Primary Care: Is structured in five sections: - The building blocks of primary care: its structure and connection with secondary care, the consultation, the process of making a diagnosis, prescribing, and ethical issues - Health promotion - Common and important presenting problems in roughly chronological order - Cancer - Death and palliative care Gives advice on how to phrase questions when consulting with patients and how to present information to patients Provides advice on how management extends to prescribing - often missing from current textbooks Contains case studies within each chapter which reflect the variety of primary care and provide top tips and advice for consulting with patients Supported by a companion website at www.wileyessential.com/primarycare featuring MCQs, EMQs, cases and OSCE checklists

Extremely Preterm Birth and its Consequences - The ELGAN Study (Hardcover): O Dammann Extremely Preterm Birth and its Consequences - The ELGAN Study (Hardcover)
O Dammann
R2,749 Discovery Miles 27 490 Ships in 10 - 15 working days

This book reviews important findings from the Extremely Low Gestational Age Newborn Study (ELGAN), the largest cohort study ever completed involving individuals born extremely prematurely. With a focus on pre-, peri-, and post-natal inflammation, this study identified potentially modifiable risk factors and pathways antecedent to a broad range of neurodevelopmental impairments, as well as asthma and obesity, during middle childhood. These findings will be of interest to both practicing neonatologists and developmental paediatricians, as well as researchers interested in the prevention of adverse child health outcomes and promotion of positive health among individuals born extremely preterm. The only book to summarise findings from the Extremely Low Gestational Age Newborn Study, the largest and most comprehensive cohort study ever conducted of this high-risk group. A comprehensive 'one-stop-shopping' resource. A broad range of neurodevelopmental outcomes are included, as well as the relationship of these outcomes to pre-, peri-, and post-natal risk factors. A focus of the study was perinatal inflammation, and the methods used to evaluate inflammation are the most comprehensive ever undertaken in an epidemiologic study of individuals born extremely preterm. The results of the ELGAN study will help Make a difference in the care and outcome of children born very early and make an important contribution to preventing learning and behavioural problems in children.

KHK-Schulungsprogramm Kardio-Fit - Unterrichtsmappe (Paperback, 1. Aufl. 2019): Martin Dürsch, Ulrike Didjurgeit KHK-Schulungsprogramm Kardio-Fit - Unterrichtsmappe (Paperback, 1. Aufl. 2019)
Martin Dürsch, Ulrike Didjurgeit
R5,532 R4,797 Discovery Miles 47 970 Save R735 (13%) Ships in 10 - 15 working days
Netter's Introduction to Clinical Procedures (Paperback): Marios Loukas, R. Shane Tubbs, Joseph Feldman Netter's Introduction to Clinical Procedures (Paperback)
Marios Loukas, R. Shane Tubbs, Joseph Feldman
R1,234 Discovery Miles 12 340 Ships in 10 - 15 working days

Written with the student in mind, Netter's Introduction to Clinical Procedures, by Drs. Marios Loukas, R. Shane Tubbs, and Joseph Feldman, uses the well-known Netter anatomy art as a foundation for reinforcing the relevant clinical anatomy needed to successfully understand and perform basic procedures. Learn the practical application of this knowledge with step-by-step guides incorporating concise text, interactive images, and animation. Didactic Netter illustrations provide clear informative visuals for quick understanding of anatomical relationships. Concise explanations enhance understanding of clinical underpinnings and implications. More than 30 common clinical procedures are explained and demonstrated with step-by-step illustrations. Multiple choice questions reinforce key concepts and challenge your knowledge. Student Consult eBook version included with purchase. This enhanced eBook experience includes access -- on a variety of devices -- to the complete text, animation, "test yourself" images, and references from the book.

KHK-Schulungsprogramm Kardio-Fit - Verbrauchsmaterial (Paperback, 1. Aufl. 2019): Martin Dürsch, Ulrike Didjurgeit KHK-Schulungsprogramm Kardio-Fit - Verbrauchsmaterial (Paperback, 1. Aufl. 2019)
Martin Dürsch, Ulrike Didjurgeit
R2,439 Discovery Miles 24 390 Ships in 10 - 15 working days
Understanding Suicidal Behaviour - The Suicidal Process Approach to Research, Treatment & Prevention (Hardcover): K. Van... Understanding Suicidal Behaviour - The Suicidal Process Approach to Research, Treatment & Prevention (Hardcover)
K. Van Heeringen
R4,715 Discovery Miles 47 150 Ships in 18 - 22 working days

How can suicide be prevented and treated by mental health professionals?
This book offers a clinical guide to the assessment, treatment and prevention of suicidal behaviour, from a new and useful theoretical perspective - a developmental process approach. The book presents the arguments and research evidence that suicidal behaviour is not just a response to current emotional crises, but is influenced by persistent characteristics that can be defined in psychological and biological terms.
The authors bring together research-based evidence that establishes three key aspects of the developmental process approach: suicidal behaviour results from the interaction between stressful life events and an individual vulnerability; this individual vulnerability is itself the product of psychobiological factors, genetics and past life events; vulnerability, in this sense, influences how the individual perceives, interprets and reacts to adverse life events, perhaps leading to hopelessness and suicidal behaviour.
Psychologists, psychiatrists, nurses and other mental health practitioners will appreciate the conceptual and clinical value of this book based on its:

  • Description of biological and psychological developmental processes leading to suicide, integrating evidence-based information from a broad range of disciplines
  • Psychobiological definition of long- and short-tem risk factors for suicide, and innovative approach to psychological and biological targets for treatment and prevention
  • Cutting-edge discussion of implications for the study and treatment of suicidal behaviour, by some of the leading authorities in the field.


Bioethics - An Anthology, Fourth Edition (Paperback, 4th Edition): U. Schuklenk Bioethics - An Anthology, Fourth Edition (Paperback, 4th Edition)
U. Schuklenk
R1,647 Discovery Miles 16 470 Ships in 10 - 15 working days

The new edition of the classic collection of key readings in bioethics, fully updated to reflect the latest developments and main issues in the field For more than two decades, Bioethics: An Anthology has been widely regarded as the definitive single-volume compendium of seminal readings on both traditional and cutting-edge ethical issues in biology and medicine. Acclaimed for its scope and depth of coverage, this landmark work brings together compelling writings by internationally-renowned bioethicist to help readers develop a thorough understanding of the central ideas, critical issues, and current debate in the field. Now fully revised and updated, the fourth edition contains a wealth of new content on ethical questions and controversies related to the COVID-19 pandemic, advances in CRISPR gene editing technology, physician-assisted death, public health and vaccinations, transgender children, medical aid in dying, the morality of ending the lives of newborns, and much more. Throughout the new edition, carefully selected essays explore a wide range of topics and offer diverse perspectives that underscore the interdisciplinary nature of bioethical study. Edited by two of the field's most respected scholars, Bioethics: An Anthology: Covers an unparalleled range of thematically-organized topics in a single volume Discusses recent high-profile cases, debates, and ethical issues Features three brand-new sections: Conscientious Objection, Academic Freedom and Research, and Disability Contains new essays on topics such as brain death, life and death decisions for the critically ill, experiments on humans and animals, neuroethics, and the use of drugs to ease the pain of unrequited love Includes a detailed index that allows the reader to easily find terms and topics of interest Bioethics: An Anthology, Fourth Edition remains a must-have resource for all students, lecturers, and researchers studying the ethical implications of the health-related life sciences, and an invaluable reference for doctors, nurses, and other professionals working in health care and the biomedical sciences.

Awaken Your Medical Intuition - The Healthcare Professional's Guide to Energy Healing (Paperback): Vivian S de Guzman Awaken Your Medical Intuition - The Healthcare Professional's Guide to Energy Healing (Paperback)
Vivian S de Guzman
R300 Discovery Miles 3 000 Ships in 10 - 15 working days

Holistic physical therapist, human MRI, and master healer Vivian S. De Guzman, PT has guided thousands toward honing their intuitive gifts for decades. Now, she writes Awaken Your Medical Intuition to help healthcare professionals harness their power so that they can make the biggest impact possible with their life and soul's purpose. Within Awaken Your Medical Intuition, Vivian shares with healthcare professionals: The truth about why they keep on avoiding their gifts as a medical intuitive The reason most doctors, healthcare professionals, empaths, and healers fail in their business The difference between people who are ready to acknowledge their medical intuitive gifts and those who are not Factors contributing to their energetic imbalances and health problems. How to align all of them to bring wealth, health, and great relationships! Practical, simple, and highly-effective tools to open and enhance their intuitive skills

Blood Cells: A Practical Guide, Sixth Edition (Hardcover, 6th Edition): BJ Bain Blood Cells: A Practical Guide, Sixth Edition (Hardcover, 6th Edition)
BJ Bain
R3,021 Discovery Miles 30 210 Ships in 9 - 17 working days

A comprehensive discussion of haematological morphology In the newly revised Sixth Edition of Blood Cells: A Practical Guide, expert haematologist Barbara J. Bain delivers a robust guide for use in the diagnostic hematology laboratory, covering methods of collection of blood specimens, blood film preparation and staining, the principles of manual and automated blood counts, and the assessment of the morphological features of blood cells. The book functions well as both a straightforward and practical bench manual and as a reference source for practicing hematologists. It has been completely updated to incorporate newly published information and 400 high-quality photographs to aid in blood cell identification. The text is comprehensive and fully supported by references. A companion website contains multiple-choice questions to aid the reader in retaining the information contained within. While the book provides additional guidance on further tests that should be performed for specific provisional diagnoses, the main focus of the text remains on microscopy and the automated full blood count. It also contains: A thorough introduction to blood sampling and blood film preparation and examination, as well as performance of blood counts Comprehensive exploration of the morphology of blood cells, detecting erroneous blood counts, and normal ranges Practical discussions of quantitative changes in blood cells and important supplementary tests In-depth examinations of disorders of red blood cells, white blood cells and platelets Review of the morphological features of blood parasites Perfect for practicing haematologists and haematology trainees, Blood Cells: A Practical Guide will also earn a place in the libraries of biomedical scientists working in laboratory settings. Many laboratories worldwide regard it as an essential bench book.

Secondary Opinions In Internal Medicine (Paperback, UK ed.): Secondary Opinions In Internal Medicine (Paperback, UK ed.)
R354 Discovery Miles 3 540 Ships in 10 - 15 working days

The problem of time wasting, unnecessary referral to specialists by primary care practitioners is universal. This book provides young doctors with a series of cases from which they can develop their judgement of whether to refer or not.

Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 1 - Regulating Mechanisms of Chemical Sensitivity... Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 1 - Regulating Mechanisms of Chemical Sensitivity (Hardcover)
William J. Rea, Kalpana Patel
R5,536 Discovery Miles 55 360 Ships in 10 - 15 working days

The clinical approaches to the chronic degenerative diseases that drain our resources, and compromise our well-being, have become almost exclusively symptom-focused. The common wisdom is that they are idiopathic with final outcomes to be managed rather than prevented or cured. That they are potentially reversible rarely enters into any discussion between doctor and patient.

A Homeostatic approach to Cure and Prevention for Researchers and Clinicians Working in Toxicology, Immunology, Neurology, and Internal Medicine

Reversibility of Chronic Degenerative Disease and Hypersensitivity, a four-part encyclopedia, offers a much different perspective on chronic degenerative disease, one that disputes the idiopathic label attached to most, as well as the usual fatalistic prognosis. The first volume, Regulating Mechanisms of Chemical Sensitivity, demonstrates that one aspect common to chronic diseases is the disruption of systemic and cellular homeostasis. Environmental pollutants play a large role, along with the contributions of genetic and life style factors, in disrupting the self-regulating mechanisms built into our normally adaptive cells.

"As dyshomeostasis develops in the nervous system, causes should be found and removed before the metabolicinduced tissue changes take place and cause autonomous, irreversible fixednamed diseases to occur. Single and multiple chemicals in various doses either individually and/or in combinations can cause individual or multiorgan dysfunction of the endocrine system. The astute clinician must be aware of these factors in order to help the patient with hypersensitivity and/or chronic degenerative disease." Chapter 2

Drawing on a vast amount of data and clinical cases attended to by the authors in their own medical practices, this volume examines the complex relation that environmental pollution has with chronic degenerative diseases. It considers its impact on the body s vast communication networks and what excessive overload does to homeostatic mechanisms.

The authors factor in both general and specific environmental loads and how they alter and trigger genetic and non-genetic responses. Volume 1 begins with an overview of the physiologic basis of homeostasis, exploring various ways that the body deals with toxins and the networks it uses to communicate news of assault and makes provisions for adaptation. The text delves into the connective tissue matrix and considers vascular, neural, endocrine, and immune system responses to a variety of noxious assaults.

"Both innate and acquired immunity can be and are altered in individuals with chemical sensitivity and chronic degenerative disease. With pollutant overload changes can occur in the lymphatic channels, the lymph nodes, and lymph node egress as well as the lymphatic cells. Changes in mucosal function and the effects of the autonomic nervous system are evident with environmental pollutant overload." Chapter 3

Written by two very knowledgeable clinicians, it brings together research of the highest caliber and provides extensive discussions involving sophisticated biochemical, endocrine, and neural science. The text provides clinicians with the knowledge to understand the triggering and processes of degenerative diseases, so that they might develop more efficient treatment and prevention plans. The book also supplies the knowledge and perspective that can lead research to more effective treatments.

"The ground regulation system consisting of the connective tissue matrix, fibroblast, macrophages, mast cell, leukocyte, end capillary vessel and autonomic nerves, is a global information system for regulating the dynamics of homeostasis in the body. One s knowledge of this process must be the guide to move through the onset of early end-stage disease and, eventually, see the manifestations to fixed-named autonomous diseases. It is this knowledge that offers us the greatest potential for preventing and reversing early homeostatic dysfunction." Chapter 1

101 Top Tips in Medicine - Cynical and Otherwise (Paperback, 1 New Ed): John Larkin 101 Top Tips in Medicine - Cynical and Otherwise (Paperback, 1 New Ed)
John Larkin
R1,032 Discovery Miles 10 320 Ships in 10 - 15 working days

The 101 vital medical tips other textbooks don't teach you - Following the success of the award winning Cynical Acumen, John Larkin outlines key knowledge for medical students and junior doctors. Clustered around the headings of cynical, survival, clinical, career and miscellaneous tips, gems on offer here include: * Don't tell the patient what you're examining unless it's absolutely necessary * Always put your hand on the bed before sitting on it * Status epilepticus starts at twenty minutes * Don't have an affair with your secretary * Pick an idiosyncratic format for your tea/coffee. Packed with anecdotes and with fully explained rationales for each tip, there's more memorable - and sometimes downright vital - information in this book than you could hope for

Medicine for Finals and Beyond (Paperback): John Axford, Chris O'Callaghan Medicine for Finals and Beyond (Paperback)
John Axford, Chris O'Callaghan
R1,691 Discovery Miles 16 910 Ships in 9 - 17 working days

Clinically-orientated and focused squarely on the core curriculum, Medicine for Finals and Beyond delivers what medical students need to know in a manner that encourages learning and recall. The consistent, easy-to-navigate structure makes locating information simple and is tailored for exam success. Highly illustrated throughout, notes based information is supplemented by 'At A Glance textboxes', 'Emergency Presentations' and 'Must Know Checklists' for quick reference, while online question and answer material allows for self-testing during that inevitable last-minute revision. Key features: * Comprehensive - everything you need to know to pass your medical finals in a single volume * Accessible - systems-based chapters all follow a common structure * Convenient - summarises the ideal approach to the patient, including history and examination, clinical presentations, differential diagnosis and investigations * Focused - covers all the common conditions that medical students need to know for future practice * Relevant - designed with input from lecturers and students This brand-new revision aid for medical students will be a convenient companion throughout clinical studies and an ideal aide-memoire for those approaching their final examinations.

Handbook of Mind-Body Medicine for Primary Care (Hardcover): Donald P Moss, Angele V. McGrady, Terence C. Davies, Ian... Handbook of Mind-Body Medicine for Primary Care (Hardcover)
Donald P Moss, Angele V. McGrady, Terence C. Davies, Ian Wickramasekera
R4,540 Discovery Miles 45 400 Ships in 10 - 15 working days

"It is a very thorough and up-to-date clinical handbook and reference for the primary care Doc or nurse. . . . if you have a favorite Family Doc or Internist or Nurse Practitioner--or administrator--and you want them to have a nice gift, buy them this book. But read it before you give it away."
--JOURNAL OF NEUROTHERAPY

The Handbook of Mind-Body Medicine for Primary Care introduces an evidence-based mind-body approach to the medical and behavioral problems of primary care patients. Evidence-based mind-body practice draws on the best available scientific research and advocates the integration of well-documented mind-body therapies into primary health care. The handbook summarizes current mind-body practice and provides an overview of the basic techniques, including biofeedback, neurofeedback, relaxation therapies, hypnotherapy, cognitive-behavioral therapies, acupuncture, and spiritual therapies. The editors also thoroughly demonstrate the application of these techniques to common disorders such as headache, chronic pain, and essential hypertension, as well as anxiety, depression, chronic fatigue syndrome, fibromyalgia, and sleep disorders.

The Handbook includes educational models with guidelines for physicians, nurses, physicians? assistants, and behavioral health practitioners. The book closes with a look at the existential and spiritual side of the human encounter with sickness and disease. This handbook will benefit a wide variety of health providers in primary care.

The Handbook is divided into four parts:

  • Part I introduces the conceptual models from the psychophysiological perspective for understanding functional medical problems.
  • Part II describes specific clinical tools and interventions.
  • Part III overviews the best documented cognitive-behavioral approaches and alternative therapies to common disorders.
  • Part IV provides educational models for practitioners in each of the mind-body disciplines.

About the Editors

 

Donald Moss, Ph.D., is Director of Chronic Pain Services at West Michigan Behavioral Health Services.

Angele V. McGrady, Ph.D., is a Professor of Psychiatry and Adjunct Professor of Physiology and Molecular Medicine at Medical College of Ohio.

Terence C. Davies, MD, is Chairman of Family and Community Medicine at Eastern Virginia Medical School.

Ian Wickramasekera, Ph.D., is a Professor of psychology at Saybrook Graduate School, Clinical Professor of Psychiatry at Stanford Medical School, and Professor of Family Medicine at Eastern Virginia Medical School.


Complete Guide to Nutrition in Primary Care (Paperback, Twelfth): D Deen Complete Guide to Nutrition in Primary Care (Paperback, Twelfth)
D Deen
R1,412 Discovery Miles 14 120 Ships in 10 - 15 working days

The Complete Guide to Nutrition in Primary Care Edited by Darwin Deen, MD, MS Lisa Hark, PhD, RD Clinicians and patients agree that primary care office visits should include routine nutrition assessment and counseling. But how do you fit it into an already crowded consultation? And what is the most up-to-date advice? With The Complete Guide to Nutrition in Primary Care, Drs. Deen and Hark provide the necessary tools. This comprehensive overview of nutrition answers your questions on: * Nutrition as Preventive Medicine * Nutrition through the Lifecycle * Improving Health by Changing Diet and Lifestyle Behaviors * Vitamins, Minerals, Dietary Supplements, and the Alternative * Successful Changes to the Environment This timely paperback contains everything the primary care clinician needs to counsel patients on diet and lifestyle issues. Keep it close at hand for the frequent consultation it is sure to receive. Dr. Darwin Deen is one of the nation's foremost authorities on nutrition. Currently Professor of Clinical, Family and Social Medicine and Director of Medical Student Education at the Albert Einstein College of Medicine in New York, he has trained a generation of physicians on the connection between nutrition and health. He has played a leading role in revising medical school curricula to incorporate nutrition training. An award-winning teacher and noted author, he serves as Chair of the Task Force on Medical Nutrition Education of the American College of Nutrition and co-chairs the Group on Nutrition of the Society of Teachers of Family Medicine. His years of experience as a family physician make him perfectly suited to advise clinicians on counseling their patients on diet and lifestyle. Dr. Lisa Hark is a renowned family nutrition expert, with more than 20 years of experience in nutrition counseling and promoting the benefits of healthy eating in children and adults. As Director of the Nutrition Education Program at the University of Pennsylvania School of Medicine in Philadelphia, she developed a model medical school curriculum and textbook, Medical Nutrition and Disease, which has become one of the most widely used texts in nutrition education. She was given the Excellence in Medical/Dental Nutrition Education award from the American Society for Nutrition. Dr. Hark was also the host of the TV show, "Honey, We're Killing the Kids," which airs on TLC, and is a widely sought after speaker who communicates nutrition concepts effectively to health professionals, patients, and the media. Approved by the American Dietetic Association for 42 Continuing Education (CE) credits www.blackwellmedicine.com

MRCP Part 2 Self-Assessment - Medical Masterclass Questions and Explanatory Answers (Paperback, 1st New edition): John D.... MRCP Part 2 Self-Assessment - Medical Masterclass Questions and Explanatory Answers (Paperback, 1st New edition)
John D. Firth, Barbara Nichols
R1,390 Discovery Miles 13 900 Ships in 10 - 15 working days

"MRCP Part 2 Self-Assessment" is the perfect revision aid. Drawn from the highly successful Medical Masterclass material from the Royal College of Physicians of London, this concise volume is specifically designed to cover the topics and format found in the Membership to the Royal College of Physicians (MRCP) Part 1 examination. The large scale, lavishly illustrated, full-colour format makes it easy to comprehend complex topics.With contributions from an extensive list of prestigious and authoritative professionals, the questions cover all areas of assessment, including the scientific background the medicine, general clinical skills, acute medicine and a range of specialties. It is ideal for examination MRCP candidates, doctors preparing for the European Diploma in internal medicine and junior doctors wanting to revise their knowledge and skills.'This collection of self-assessment questions and explanatory answers has been drawn from Medical Masterclass, which is produced and published by the Royal College of Physicians of London. The questions have been specifically written to help doctors in their first few years of training to test and revise their medical knowledge and skills; and in particular to pass postgraduate examinations, such as the MRCP(UK)' - John D Firth, in the Introduction.

Clinical Skills for OSCEs (Hardcover, 2nd edition): Neel L Burton, Kuldip Birdi Clinical Skills for OSCEs (Hardcover, 2nd edition)
Neel L Burton, Kuldip Birdi
R1,410 Discovery Miles 14 100 Ships in 10 - 15 working days

This Second Edition of the highly popular Clinical Skills for OSCEs is the most comprehensive guide to basic clinical skills available, covering all the pertinent skills taught at medical school, from third year to finals. With its clear and concise, yet informative style, Clinical Skills for OSCEs, Second Edition is the ideal revision tool for all exam candidates preparing for their OSCE or PLAB exams.

Lung and Heart-Lung Transplantation (Hardcover): Joseph P. Lynch, David J. Ross Lung and Heart-Lung Transplantation (Hardcover)
Joseph P. Lynch, David J. Ross
R6,153 Discovery Miles 61 530 Ships in 10 - 15 working days

A comprehensive review of clinical and exploratory aspects of lung (LT) and heart-lung transplantation (HLT), this reference focuses on cumulative data from the International Registry with data on outcomes associated with LT and HLT worldwide. Collecting in-depth discussions on graft dysfunction, infectious complications, and indications of LT for specific disease states including emphysema, cystic fibrosis, myriad interstitial lung diseases, and pulmonary hypertension, this guide explores the most current technologies and best practices affecting lung and heart-lung transplant surgeries.

Particle Toxicology (Hardcover, New): Ken Donaldson, Paul Borm Particle Toxicology (Hardcover, New)
Ken Donaldson, Paul Borm
R5,234 Discovery Miles 52 340 Ships in 10 - 15 working days

Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to translocate to the bloodstream, the brain, and other target sites. The new questions posed by nanoparticles underscore the importance of interdisciplinary research and exchange and highlight the need for new collaborations among disciplines in medicine, toxicology, chemistry, and material sciences. Particle Toxicology brings together the state of the science in particle physico-chemistry, cell biology, and toxicology in a single volume. While organized around the classical toxicology paradigm of exposure - dose - response, the book is unique in its emphasis on mechanistic toxicology. Preparing the reader with a brief historical overview and a conceptual framework for particle research, the book provides reviews on the mechanisms and properties of pathogenic particles and their effects on target cells at various sites in the body. The text describes how adverse effects are a consequence of deposition, translocation, and the complex issue of "dose" dominates. Contributions from leading researchers address particle-associated pro-inflammatory effects and inflammatory signaling, cellular and extracellular oxidative and nitrosative stress, particulate interactions in the pulmonary, cardiovascular, and central nervous systems, as well as genotoxic effects. Exemplar particles include quartz, asbestos, particulate material and nanoparticles. The book also covers mathematical modeling and human studies as avenues for future research. Responding to the evolving trend of consumer applications for particulate matter, Particle Toxicology provides the comprehensive resource for current knowledge from which to develop ne

Angiotensin II Receptor Antagonists - Current Perspectives (Hardcover, 2nd edition): Giuseppe Mancia Angiotensin II Receptor Antagonists - Current Perspectives (Hardcover, 2nd edition)
Giuseppe Mancia
R3,364 Discovery Miles 33 640 Ships in 10 - 15 working days

Since angiotensin II is one of the most potent vasoconstrictors and an important stimulus for the secretion of aldosterone from the adrenal gland, the development of of angiotensin II inhibitors is an important step in regulating blood pressure. This class of drug is well-tolerated by pateints and these drugs have the added advantage over ACE inhibitors in that they are not associated with cough. Because most drugs can be given once daily and, like ACEIs, they have a useful additive hypotensive effect in combination with diuretics, they are a welcome therapeutic tool in the treatment of hypertension. This Second Edition builds on the success of the first and brings to the reader all the latest developments, clinical trial data, and the contributors's personal perspectives when treating patients with angiotensin II receptors antagonists. -offers chapters by well-known contributors in the fields of both hypertension and heart failure, especially with regard to pharmacological interventions -covers the new role of AIIR in neuroprotection -builds upon the strengths of the first edition

Rapid Review of Clinical Medicine for MRCP Part 2 (Paperback, 2nd edition): Sanjay Sharma, Rashmi Kaushal Rapid Review of Clinical Medicine for MRCP Part 2 (Paperback, 2nd edition)
Sanjay Sharma, Rashmi Kaushal
R2,628 Discovery Miles 26 280 Ships in 10 - 15 working days

This book is an invaluable resource with 400 self-assessment cases and data interpretation questions covering all aspects of internal medicine. It has great breadth of coverage, superb illustration, lively presentation, precise answers and detailed discussion.

CBT for Hoarding Disorder - A Group Therapy Program Workbook (Paperback): D Tolin CBT for Hoarding Disorder - A Group Therapy Program Workbook (Paperback)
D Tolin
R914 Discovery Miles 9 140 Ships in 10 - 15 working days

Part of a two-component product with a companion therapist's guide, CBT for Hoarding Disorder: Client Workbook guides patients struggling with hoarding disorder who are enrolled in a comprehensive CBT group program through the therapeutic process of addressing and overcoming their difficulties. Designed for participants in group cognitive-behavioral therapy for hoarding disorder - an evidence-based program created by experts in the field Helps readers to work on the many factors that contribute to ongoing difficulties with clutter, in order to learn how to make quicker, more efficient decisions that are less stressful and draining. Addresses many of the barriers to successful decluttering, such as time management, organizational skills, and problem-solving Shows that while living with hoarding disorder can be frustrating, both for the sufferer and for family and friends, there is a way forward and nobody has to live with clutter.

Lung Injury - Mechanisms, Pathophysiology, and Therapy (Hardcover): Robert H. Notter, Jacob Finkelstein, Bruce Holm Lung Injury - Mechanisms, Pathophysiology, and Therapy (Hardcover)
Robert H. Notter, Jacob Finkelstein, Bruce Holm
R6,138 Discovery Miles 61 380 Ships in 10 - 15 working days

Progressing from general scientific principles and concepts to in-depth topical discussions of current research and treatment methods, this comprehensive reference defines the cellular and molecular mechanisms contributing to inflammatory lung injury and repair. Extensive coverage is provided on key mediators and pathways important in acute and chronic pulmonary inflammation and lung injury, as well as the mechanistic pathophysiology of related diseases ranging from clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) to idiopathic pulmonary fibrosis (IPF) and other subacute and chronic conditions. Additional chapters also address vascular dysfunction, surfactant dysfunction, reactive oxygen/nitrogen species, and cell and animal models of acute and chronic lung injury.

Healthy Aging in Asia (Paperback): Karen Eggleston Healthy Aging in Asia (Paperback)
Karen Eggleston
R754 Discovery Miles 7 540 Ships in 10 - 15 working days

How are health systems in Asia promoting evidence based policies for healthy aging? What strategies have been tried to prevent noncommunicable chronic diseases, screen for early detection, raise quality of care, improve medication adherence, reduce unnecessary hospitalizations, and increase "value for money" in health spending?The chapters of this book contribute to the literature on how diverse economies of Asia are preparing for older population age structures and transforming health systems to support patients who will live with chronic disease for decades. Fifteen concise chapters cover multiple aspects of policy initiatives for healthy aging and economic research on diabetes and hypertension control in health systems as diverse as cities such as Singapore and Hong Kong, to large economies such as Japan, India, and China. Topics include precision health and personalized medicine in Japan; China's evolving family doctor system and its national demonstration areas for chronic disease control; cancer disparities and public private roles in Taiwan; and policies for healthy aging in Korea and India. Several chapters draw on research led by the Stanford Asia Health Policy Program on the net value of chronic disease management programs throughout Asia, starting with analysis of detailed longitudinal, patient level data on diabetes management as a lens for understanding the net value of medical spending for patients with complicated chronic diseases across diverse health systems.

Ion Channels in the Pulmonary Vasculature (Hardcover, New): Jason X.-J. Yuan Ion Channels in the Pulmonary Vasculature (Hardcover, New)
Jason X.-J. Yuan
R4,144 R3,557 Discovery Miles 35 570 Save R587 (14%) Ships in 10 - 15 working days

This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and characterized in pulmonary artery smooth muscle, as well as a practical discussion of experimental tools for the study of ion channel physiology and molecular biology.

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