Part of a two-component product with a companion therapist's guide, CBT for Hoarding Disorder: Client Workbook guides patients struggling with hoarding disorder who are enrolled in a comprehensive CBT group program through the therapeutic process of addressing and overcoming their difficulties. Designed for participants in group cognitive-behavioral therapy for hoarding disorder - an evidence-based program created by experts in the field Helps readers to work on the many factors that contribute to ongoing difficulties with clutter, in order to learn how to make quicker, more efficient decisions that are less stressful and draining. Addresses many of the barriers to successful decluttering, such as time management, organizational skills, and problem-solving Shows that while living with hoarding disorder can be frustrating, both for the sufferer and for family and friends, there is a way forward and nobody has to live with clutter.

Now fully revised and updated, Clinical Biochemistry, third edition is essential reading for specialty trainees, particularly those preparing for postgraduate examinations. It is also an invaluable current reference for all established practitioners, including both medical and scientist clinical biochemists. Building on the success of previous editions, this leading textbook primarily focuses on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management - including nutritional disorders, diabetes, inherited metabolic disease, metabolic bone disease, renal calculi and dyslipidaemias. The acquisition and interpretation of clinical biochemical data are also discussed in detail. From the author of the popular Clinical Chemistry medical student textbook there are many competing texts on clinical chemistry, the vast majority concentrate on the technology; this book concentrates on the clinical Ideally suited for preparation for the MRCPath and similar examinations Expanded sections on haematology and immunology for clinical biochemists provide a thorough understanding of both laboratory and clinical aspects New chapters are included on important evolving areas such as the metabolic response to stress, forensic aspects of clinical biochemistry and data quality management An extended editorial team - including three expert new additions - ensures accuracy of information and relevance to current curricula and clinical practice A superb new accompanying electronic version provides an enhanced learning experience and rapid reference anytime, anywhere! Elsevier ExpertConsult.com Enhanced eBooks for medical professionals Compatible with PC, Mac (R), most mobile devices and eReaders, browse, search, and interact with this title - online and offline. Redeem your PIN at expertconsult.com today! Straightforward navigation and search across all Elsevier titles Seamless, real-time integration between devices Adjustable text size and brightness Notes and highlights sharing with other users through social media Interactive content

Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to translocate to the bloodstream, the brain, and other target sites. The new questions posed by nanoparticles underscore the importance of interdisciplinary research and exchange and highlight the need for new collaborations among disciplines in medicine, toxicology, chemistry, and material sciences. Particle Toxicology brings together the state of the science in particle physico-chemistry, cell biology, and toxicology in a single volume. While organized around the classical toxicology paradigm of exposure - dose - response, the book is unique in its emphasis on mechanistic toxicology. Preparing the reader with a brief historical overview and a conceptual framework for particle research, the book provides reviews on the mechanisms and properties of pathogenic particles and their effects on target cells at various sites in the body. The text describes how adverse effects are a consequence of deposition, translocation, and the complex issue of "dose" dominates. Contributions from leading researchers address particle-associated pro-inflammatory effects and inflammatory signaling, cellular and extracellular oxidative and nitrosative stress, particulate interactions in the pulmonary, cardiovascular, and central nervous systems, as well as genotoxic effects. Exemplar particles include quartz, asbestos, particulate material and nanoparticles. The book also covers mathematical modeling and human studies as avenues for future research. Responding to the evolving trend of consumer applications for particulate matter, Particle Toxicology provides the comprehensive resource for current knowledge from which to develop ne

This Second Edition of the highly popular Clinical Skills for OSCEs is the most comprehensive guide to basic clinical skills available, covering all the pertinent skills taught at medical school, from third year to finals. With its clear and concise, yet informative style, Clinical Skills for OSCEs, Second Edition is the ideal revision tool for all exam candidates preparing for their OSCE or PLAB exams.

A comprehensive review of clinical and exploratory aspects of lung (LT) and heart-lung transplantation (HLT), this reference focuses on cumulative data from the International Registry with data on outcomes associated with LT and HLT worldwide. Collecting in-depth discussions on graft dysfunction, infectious complications, and indications of LT for specific disease states including emphysema, cystic fibrosis, myriad interstitial lung diseases, and pulmonary hypertension, this guide explores the most current technologies and best practices affecting lung and heart-lung transplant surgeries.

Fosters a thorough understand of radiation dosimetry concepts: detailed solutions to the exercises in the textbook "Fundamentals of Ionizing Radiation Dosimetry"!

This reference surveys current best practices in the prevention and management of ventilator-induced lung injury (VILI) and spans the many pathways and mechanisms of VILI including cell injury and repair, the modulation of alveolar-capillary barrier properties, and lung and systemic inflammatory consequences of injurous mechanical ventilation. Considering many emerging therapeutic options, this guide also reviews the wide array of clinical studies on lung protection strategies and approaches to ARDS patients at risk for VILI.

Since angiotensin II is one of the most potent vasoconstrictors and an important stimulus for the secretion of aldosterone from the adrenal gland, the development of of angiotensin II inhibitors is an important step in regulating blood pressure. This class of drug is well-tolerated by pateints and these drugs have the added advantage over ACE inhibitors in that they are not associated with cough. Because most drugs can be given once daily and, like ACEIs, they have a useful additive hypotensive effect in combination with diuretics, they are a welcome therapeutic tool in the treatment of hypertension. This Second Edition builds on the success of the first and brings to the reader all the latest developments, clinical trial data, and the contributors's personal perspectives when treating patients with angiotensin II receptors antagonists. -offers chapters by well-known contributors in the fields of both hypertension and heart failure, especially with regard to pharmacological interventions -covers the new role of AIIR in neuroprotection -builds upon the strengths of the first edition

This book is an invaluable resource with 400 self-assessment cases and data interpretation questions covering all aspects of internal medicine. It has great breadth of coverage, superb illustration, lively presentation, precise answers and detailed discussion.

This book provides a detailed overview of the function of the nervous system in fever and its role in antipyresis. The volume opens with an introductory account of fever, its physiology and adaptive role, and explains the mechanisms of thermoregulation. Sufficient information about bacterial pyrogens, 'endogenous' pyrogenic cytokines, body temperature regulation and survival value of fever and its ubiquity is given to enable readers to follow the central nervous system's involvement. The book should enable graduate students and researchers in neuroscience and other disciplines to understand the impact of their studies in the overall processes of fever. It will also be of benefit to pharmacologists studying anti-pyretics and the central nervous system function of these drugs. Academic clinicians will find this a more comprehensive overview of fever than other available texts. Finally, the author challenges some well-established dogmas in this area and sets an agenda for future research.

This volume presents a global overview of the role of ion flux via transmembrane ion channel proteins in the regulation of pulmonary vascular tone and in the vascular remodeling processes associated with pulmonary vascular disease-offering a comprehensive review of the multiple families of ion channels that have been identified and characterized in pulmonary artery smooth muscle, as well as a practical discussion of experimental tools for the study of ion channel physiology and molecular biology.

This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.

How are health systems in Asia promoting evidence based policies for healthy aging? What strategies have been tried to prevent noncommunicable chronic diseases, screen for early detection, raise quality of care, improve medication adherence, reduce unnecessary hospitalizations, and increase "value for money" in health spending?The chapters of this book contribute to the literature on how diverse economies of Asia are preparing for older population age structures and transforming health systems to support patients who will live with chronic disease for decades. Fifteen concise chapters cover multiple aspects of policy initiatives for healthy aging and economic research on diabetes and hypertension control in health systems as diverse as cities such as Singapore and Hong Kong, to large economies such as Japan, India, and China. Topics include precision health and personalized medicine in Japan; China's evolving family doctor system and its national demonstration areas for chronic disease control; cancer disparities and public private roles in Taiwan; and policies for healthy aging in Korea and India. Several chapters draw on research led by the Stanford Asia Health Policy Program on the net value of chronic disease management programs throughout Asia, starting with analysis of detailed longitudinal, patient level data on diabetes management as a lens for understanding the net value of medical spending for patients with complicated chronic diseases across diverse health systems.

Progressing from general scientific principles and concepts to in-depth topical discussions of current research and treatment methods, this comprehensive reference defines the cellular and molecular mechanisms contributing to inflammatory lung injury and repair. Extensive coverage is provided on key mediators and pathways important in acute and chronic pulmonary inflammation and lung injury, as well as the mechanistic pathophysiology of related diseases ranging from clinical acute lung injury (ALI) and the acute respiratory distress syndrome (ARDS) to idiopathic pulmonary fibrosis (IPF) and other subacute and chronic conditions. Additional chapters also address vascular dysfunction, surfactant dysfunction, reactive oxygen/nitrogen species, and cell and animal models of acute and chronic lung injury.

Psychodynamic Formulation A leading text for psychodynamic clinicians and practitioners Psychodynamic Formulation: An Expanded Approach delivers an exceptional exploration of psychodynamic explanations and hypotheses that seek to explain how a person's conscious and unconscious thoughts and feelings may have developed and may be causing or contributing to the challenges they face. This latest edition of the leading reference includes a refreshed and reinvigorated emphasis on the impacts of culture and society, as well as the importance of diversity and inclusion, on psychodynamic formulation. It puts new focus on lived experience, including trauma, and on how clinical bias can contribute to the perpetuation of trauma. In addition to newly included activities and exercises, readers will find: A practical, step-by-step guide to collaboratively creating psychodynamic formulations Comprehensive discussions about how what we're born with and environmental influences contribute to development Suggestions for using psychodynamic formulations in many clinical settings, including acute care and psychopharmacologic treatment An educator's guide to teaching psychodynamic formulation Perfect for mental health practitioners with a professional or personal interest in psychodynamics/psychoanalysis, Psychodynamic Formulation: An Expanded Approach will earn a place in the libraries of trainees in all mental health fields.

OSCEs for Medical Finals has been written by doctors from a variety of specialties with extensive experience of medical education and of organising and examining OSCEs. The book and website package consists of the most common OSCE scenarios encountered in medical finals, together with checklists, similar to OSCE mark schemes, that cover all of the key learning points students need to succeed. Each topic checklist contains comprehensive exam-focussed advice on how to maximise performance together with a range of insider's tips' on OSCE strategy and common OSCE pitfalls. Designed to provide enough coverage for those students who want to gain as many marks as possible in their OSCEs, and not just a book which will ensure students scrape a pass', the book is fully supported by a companion website at www.wiley.com/go/khan/osces, containing: * OSCE checklists from the book * A survey of doctors and students of which OSCEs have a high chance of appearing in finals in each UK medical school

Does the psyche have an affect on health? The Psyche of the Body is a passionate and well-informed plea for a Jungian version of psychosomatic medicine and psychotherapy. Many cases of physical illness show evidence of the effect of psychic involvement, both in origin and treatment. Yet to date the majority of study into psychosomatic illness has been purely empirical, with little theory to help interpret and put results into context. Illustrated by vivid clinical illustrations of case histories, The Psyche of the Body reviews the long history of psychosomatic medicine and models of the relationship between psyche and body that have evolved over time, and presents a full revision of research in the field over the last twenty years. It presents a much-needed theoretical model together with practical guidelines that demonstrate how the psychological aspects of specific illnesses should be handled in therapy and analysis. Practicing and training Jungian analysts, as well as all those involved in clinical treatment, will find the interdisciplinary approach to psychosomatic medicine promoted in this book fascinating reading.

This working manual has been developed to ensure that all health professionals involved in immunization will be both knowledgable about procedures and confident about their benefits. It shows the practitioner how to give vaccines safely and how to inform parents. The book is line with the new and revised "Immunization Against Infectious Disease" produced by the Department of Health, but is written in a practical and easily accessible form. As well as being aimed at general practitioners, health visitors, school health nurses, practice nurses, clinical medical officers and district nurses, the book has been written in such a fashion as to be understandable by parents. It has sections giving answers to the questions most frequently asked by parents, and to the most common problems. In addition, the book is adaptable for local use, with space for key contacts and `phone numbers.

Contents:
1. The Importance of Rhinitis 2. Causes of Rhinitis 3. Making a Diagnosis 4. Examination 5. Investigations 6. Airway Tests 7. Tests of Mucociliary Clearance 8. Imaging 9. Other Tests

Focusing specifically on the inter-relationship between the nose and the lungs, this reference examines the structural connections between the upper and lower airways and explores the microscopic and gross anatomy of the respiratory tract. Considering functional relationships, as well as human and animal models of disease, this source delivers articles on the pathophysiology, epidemiology, diagnosis and treatment of allergic airway dysfunction and other illnesses affecting the entire respiratory tract.

Help your clients achieve victory over chronic pain and lead more fulfilling lives This insightful and informative book will help you deliver better pain management services to the people you care for. Incorporating biomedical, surgical, psychological, social, and spiritual perspectives, it provides vital, up-to-date information about how to reduce physical pain and explores techniques for improving people's ability to cope with it. Helpful tables provide easy access to information on medications for pain and managing side effects. Chronic Pain: Biomedical and Spiritual Approaches is filled with resources for the person in pain and for the health or religious professionals working to help them. It gives you very specific suggestions on how to manage chronic pain, including detailed information about medications, alternative therapies, psychological treatments, and spiritual strategies for pain management. The book is completed by two thoughtful appendixes: one examining pain medications and ways to manage their side effects and the other providing scriptural passages that can comfort those in pain. In addition to his experiences treating patients with chronic pain, the author suffers from chronic pain and disability himself. In this very personal book, he explores ways to help people coping with: low back pain fibromyalgia rheumatologic pain headaches the pain of multiple sclerosis other types of chronic unrelenting pain Chronic Pain: Biomedical and Spiritual Approaches can help people in pain and their families by showing them how to lead satisfying, joy-filled lives--whether their pain goes away or not. It is an essential reference book for everyone who works with pain sufferers as well as patients and their families

Interaction between professionals/students in various disciplines leads to greater respect, cooperation, and practical knowledge for all!Interprofessional Collaboration in Occupational Therapy, written by experienced occupational therapists, examines successful programs and models of practice involving collaboration between OT clinicians and allied health professionals. This vital information can help you deliver services to the elderly, the underserved, and the chronically ill that are more effective than traditional primary care models.This book will show you how to apply the concepts of interprofessional collaboration to: increase professional competence and public accountability improve the cost-effectiveness of the way your resources are used gain better evidence-based decision-making skills make more effective referrals avoid duplication of services to clients make better use of faculty time and classroom space by teaching subjects common to various health professions--anatomy, physiology, kinesiology, and other basic sciences

An A-to-Z look at these crippling disorders! Compiled by one of the foremost researchers in the field of immunology, The Concise Encyclopedia of Fibromyalgia and Myofascial Pain is an A-to-Z summary of current knowledge that updates patients and health care professionals on these disabling clinical disorders. This vital information has been organized in an easy-to-use format that lets you become familiar with highlights of the most relevant topics.The Concise Encyclopedia of Fibromyalgia and Myofascial Pain gives you immediate access to the latest advances in rheumatology, cardiovascular medicine, endocrinology, epidemiology, immunology, infectious diseases, neurology, psychiatry, and psychology that form the basis for new lines of research and therapeutic intervention. This comprehensive reference summarizes information published mainly in the last decade, providing a thoughtful and balanced resource that will educate and increase awareness of these often-misdiagnosed disorders. The Concise Encyclopedia of Fibromyalgia and Myofascial Pain allows easy access to: relevant case study findings, summarized to provide the answers you need evidence-based alternative medicine approaches pertinent findings on related disorders an extensive bibliographyComprehensive and thorough, The Concise Encyclopedia of Fibromyalgia and Myofascial Pain gives you the information you've been looking for on these painful disorders that affect more than six million Americans. This important book gives health care professionals a greater understanding and awareness of fibromyalgia and myofascial pain and gives patients help at their fingertips.

The inability of the human body to be able significantly to self repair injured organs and tissues results in a considerable medical and social problem. During the last few years there has been incredible progress, and the achievements in experimental strategies for tissue regeneration, particularly in cell transplantation and stem cell research, have led to potential treatment options for many otherwise fatal conditions. These innovations hold promise for treating or preventing end-stage organ failure; cell therapy and tissue engineering of viable grafts with the potential to grow and remodel could provide prospective new solutions to the serious problems of organ donor shortage.

Regenerative medicine a" stem cell and gene-based therapy a" offers a new approach for restoring function of damaged organs and tissues. Several books have been published on particular aspects of organ and/or tissue replacement but none cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine, allowing practitioners to gain knowledge not only of how regenerative medicine applies to their discipline directly but also how it could benefit their patients in the years to come.