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Books > Medicine > Pre-clinical medicine: basic sciences > Anatomy > General

The Cytoskeleton (Paperback, Softcover reprint of the original 1st ed. 1984): Jerry Shay The Cytoskeleton (Paperback, Softcover reprint of the original 1st ed. 1984)
Jerry Shay
R2,676 Discovery Miles 26 760 Ships in 7 - 11 working days

The preceding volumes of Cell and Muscle Motility have focused on various aspects of motile systems in both muscle and non muscle cells. These essays have been critical reviews on topics of current interest and, hopefully, have provided a base from which future investigations may develop. During the past decade, however, much attention in the fields of biochemistry and cell biology has focused on motile systems in non muscle cells. Our current under- standing of the three-dimensional organization of the cytoplasm involve three major fibrous proteins which are collectively known as the cytoskeletal system. These polymorphic cytoskeletal proteins are microtubules (25-nm diameter), microfilaments (6-nm diameter), and intermediate filaments (lO-nm diame- ter). Microtubules consist of tubulin and several well-characterized micro- tubule associated proteins (MAPs) including MAP , MAP , tau, and others. l 2 Microfilaments consist of actin and associate with actin-binding proteins in- cluding a-actinin, filamin, myosin, tropomyosin, vinculin, and others. Inter- mediate filaments (lO-nm filaments) consist of at least five different tissue- specific classes, including desmin or skeletin (muscle), prekeratin (epithelial), vimentin (mesenchymal), neurofilament (nerve), and glial acidic fibrillary protein (astrocytes). These major fibrous proteins apparently interact with each other as well as other cytoplasmic components and appear to be inti- mately associated with such biological processes as cell shape changes, growth, motility, secretion, cell division, and uptake of materials from the exterior of the cell.

Gray's Atlas of Anatomy (Paperback, 3rd Revised edition): Richard Drake, A. Wayne Vogl, Adam W. M Mitchell, Richard... Gray's Atlas of Anatomy (Paperback, 3rd Revised edition)
Richard Drake, A. Wayne Vogl, Adam W. M Mitchell, Richard Tibbitts, Paul Richardson
R1,628 Discovery Miles 16 280 Ships in 10 - 15 working days

Clinically focused, consistently and clearly illustrated, and logically organized, Gray's Atlas of Anatomy, the companion resource to the popular Gray's Anatomy for Students, presents a vivid, visual depiction of anatomical structures. Stunning illustrations demonstrate the correlation of structures with clinical images and surface anatomy - essential for proper identification in the dissection lab and successful preparation for course exams. Build on your existing anatomy knowledge with structures presented from a superficial to deep orientation, representing a logical progression through the body. Identify the various anatomical structures of the body and better understand their relationships to each other with the visual guidance of nearly 1,000 exquisitely illustrated anatomical figures. Visualize the clinical correlation between anatomical structures and surface landmarks with surface anatomy photographs overlaid with anatomical drawings. Recognize anatomical structures as they present in practice through more than 270 clinical images - including laparoscopic, radiologic, surgical, ophthalmoscopic, otoscopic, and other clinical views - placed adjacent to anatomic artwork for side-by-side comparison. Gain a more complete understanding of the inguinal region in women through a brand-new, large-format illustration, as well as new imaging figures that reflect anatomy as viewed in the modern clinical setting. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices - as well as dissection videos and self-assessment questions and answers.

Introduction to Kinesiology - The Science of Human Physical Activity (Paperback, Second Revised): Marilyn Mitchell Introduction to Kinesiology - The Science of Human Physical Activity (Paperback, Second Revised)
Marilyn Mitchell
R2,728 Discovery Miles 27 280 Ships in 7 - 11 working days

"Introduction to Kinesiology: The Science of Human Physical" Activity outlines the major concepts, principles, and experimental findings for the curious yet serious student interested in the field of kinesiology. Like most fields of science, it is important to provide kinesiology students with a textbook that covers the historical development of the field, discusses career opportunities, and provides the groundwork for future coursework. It is also important to clearly articulate the limit and scope of kinesiology by defining core knowledge and to emphasize the cross-disciplinary nature of kinesiology. "Introduction to Kinesiology" was designed to meet all of these requirements.
To improve the readability and the retention of the material, the chapters in "Introduction to Kinesiology" contain several features, including:
Student ObjectivesImportant Terms"Integrating Kinesiology: Putting It All Together" - questions and exercisesSection and Chapter Summaries"Kinesiology on the Web" - web links for more information
Marilyn Mitchell, Ph.D., is a professor in the Department of Kinesiology at San Francisco State University, where she teaches Motor Learning, Neuromotor Control Processes, and Introduction to Kinesiology. Dr. Mitchell earned her Ph.D. in physical education at the University of Wisconsin-Madison with a specialization in Motor Learning and Control. She served as Chair of the Department of Kinesiology at the University of Colorado at Boulder. She has also served as president of the North American Society of Psychology of Sport and Physical Activity. Dr. Mitchell is a fellow in The National Academy of Kinesiology.

Standard Variants of the Skull and Brain - Atlas for Neurosurgeons and Neuroradiologists (Paperback, Softcover reprint of the... Standard Variants of the Skull and Brain - Atlas for Neurosurgeons and Neuroradiologists (Paperback, Softcover reprint of the original 1st ed. 2003)
Wolfgang Seeger
R2,465 Discovery Miles 24 650 Ships in 7 - 11 working days

The author describes in his unique style the anatomical variants of the brain and skull. This atlas is a continuation of his last work on "Neuronavigation and Neuroanatomy". Most anatomical reference volumes show a large number of common and rare variations. This atlas concentrates on well known and little known variants which are especially important for the clinicians, in particular the neurosurgeons and the radiologists. The variants have been grouped after areas of trepanation. The author presents also a number of so far unknown variants gathered from his personal theoretical and clinical experience of 50 years. Exact knowledge of anatomical variations which the surgeon may encounter helps to plan operations and to avoid unexpected complications. Variants of no clinical relevance, even rather common ones, have not been included.

Video Microscopy (Paperback, Softcover reprint of the original 1st ed. 1986): Shinya Inoue Video Microscopy (Paperback, Softcover reprint of the original 1st ed. 1986)
Shinya Inoue
R3,513 R3,020 Discovery Miles 30 200 Save R493 (14%) Ships in 10 - 15 working days

Ever since television became practical in the early 1950s, closed-circuit television (CCTV) in conjunction with the light microscope has provided large screen display, raised image contrast, and made the images formed by ultraviolet and infrared rays visible. With the introduction of large-scale integrated circuits in the last decade, TV equipment has improved by leaps and bounds, as has its application in microscopy. With modem CCTV, sometimes with the help of digital computers, we can distill the image from a scene that appears to be nothing but noise; capture fluorescence too dim to be seen; visualize structures far below the limit of resolution; crispen images hidden in fog; measure, count, and sort objects; and record in time-lapsed and high-speed sequences through the light microscope without great difficulty. In fact, video is becoming indispensable for harnessing the fullest capacity of the light microscope, a capacity that itself is much greater than could have been envisioned just a few years ago. The time seemed ripe then to review the basics of video, and of microscopy, and to examine how the two could best be combined to accomplish these tasks. The Marine Biological Laboratory short courses on Analytical and Quantitative Light Microscopy in Biology, Medicine, and the Materials Sciences, and the many inquiries I received on video microscopy, supported such an effort, and Kirk Jensen of Plenum Press persuaded me of its worth.

Human Stefins & Cystatins (Hardcover, Illustrated Ed): Eva Zerovnik, Natasa Kopitar-Jerala Human Stefins & Cystatins (Hardcover, Illustrated Ed)
Eva Zerovnik, Natasa Kopitar-Jerala
R3,087 R2,803 Discovery Miles 28 030 Save R284 (9%) Ships in 10 - 15 working days

This book brings up-to-date information on developments in studies of human stefins and cystatins, proteins with the function of cystein proteases (cathepsins) inhibition. The chapters start at the level of genes, go on with protein structure and function (proposal of alternative function), protein stability and folding, to mis-folding and mis-function. The book ends with chapters describing different disease states where stefins or cystatins are involved, from Alzheimer's disease, epilepsy to cancer.

Cerebral Cortex - Volume 12: Extrastriate Cortex in Primates (Paperback, Softcover reprint of the original 1st ed. 1997):... Cerebral Cortex - Volume 12: Extrastriate Cortex in Primates (Paperback, Softcover reprint of the original 1st ed. 1997)
Kathleen S. Rockland, Jon H. Kaas, Alan Peters
R7,973 Discovery Miles 79 730 Ships in 7 - 11 working days

Over the last twenty-five years, there has been an extensive effort, still growing for that matter, to explore and understand the organization of extrastriate cor tex in primates. We now recognize that most of caudal neocortex is visual in some sense and that this large visual region includes many distinct areas. Some of these areas have been well defined, and connections, neural properties, and the functional consequences of deactivations have been studied. More recently, non invasive imaging of cortical activity patterns during visual tasks has led to an expanding stream of papers on extrastriate visual cortex of humans, and results have been related to theories of visual cortex organization that have emerged from research on monkeys. Against this backdrop, the time seems ripe for a review of progress and a glance at the future. One caveat important to emphasize at the very onset is that the reader may be puzzled or confused by the use of different terminologies. Individual investi gators commonly tend to favor different terminologies, but in general some prove more advantageous than others. As discussed by Rowe and Stone (1977) as well as by others, there is an unfortunate tendency for role-indicating names to lead to fixed ideas about function, in contrast to those that are more neutral and adaptable to new findings.

Circulatory System Advanced (Fold-out book or chart): Vincent Perez Circulatory System Advanced (Fold-out book or chart)
Vincent Perez
R639 Discovery Miles 6 390 Ships in 7 - 11 working days

Our new guide on the circulatory system, illustrated by accomplished anatomical artist Vincent Perez, includes in-depth coverage of veins and arteries, including depictions over and under transparent bone to better expose the system around the head, neck, and heart, as well as separate views of major organs and extremities. From teachers and students of anatomy, to medical professionals and therapists, this guide is perfect for your medical study or practice.

Anatomy & Physiology Essential Revision - 4,000 Revision Questions (Paperback): Gerard T. Lucas Anatomy & Physiology Essential Revision - 4,000 Revision Questions (Paperback)
Gerard T. Lucas
R435 Discovery Miles 4 350 Ships in 7 - 11 working days

Anatomy & Physiology Essential Revisionbrings the subject of anatomy and physiology to life with 4,000 revision questions and answers on the structure and functions of the various body systems. This comprehensive textbook is designed for use both in the classroom and as a home study guide. Organised into separate chapters for each system of the body, it includes a variety of: Multiple choice questions Crossword puzzles Word search puzzles True/false quizzes Filling in gaps Short answer questions Matching columns These interactive questions and quizzes are a perfect way to engage students, helping them understand and retain key terminology. Each exercise is intended to test their knowledge in different ways while making it easier and more fun to learn. Anatomy & Physiology Essential Revision is suitable for students up to Level 4 and has been adopted by Occupational Therapists, Student Nurses, Biomedical Science Students, Biology Students and Complementary Therapists.

Pseudomonas (Paperback, Softcover reprint of the original 1st ed. 1998): Thomas C. Montie Pseudomonas (Paperback, Softcover reprint of the original 1st ed. 1998)
Thomas C. Montie
R5,276 Discovery Miles 52 760 Ships in 7 - 11 working days

The genus Pseudomonas represents a large group of medically and envi ronmentally important bacteria. Interest in these bacteria is reflected in the extensive number of publications devoted to original research, re views, and books on this subject. In this volume selected areas of Pseu domonas research are presented in depth by persons who have been active in their fields over many years. The extensive reviews presented are an effort to provide a balanced perspective in a number of areas not readily available in the current literature. In the style of the previous Biotechnology Handbooks most of these topics have not been reviewed at all, and several are also presented from a new direction. For example, in addition to structural and compositional aspects, the chapter on lipids provides shifts in lipid parameters that result from environmental changes. This information will be invaluable to a cross section of Pseu domonas researchers in pathogenesis and bioremediation. The chapters presented include basic aspects of plasmid biology and carbohydrate metabolism and regulation. A major emphasis is placed on the Pseudomonas aeruginosa cell surface. Chapters cover lipo polysaccharide, capsular polysaccharide and alginate, the outer mem brane, transport systems, and the flagellum. Uptake of iron is also neces sarily an important portion of the chapter on iron metabolism.

The Biology of Tumors (Paperback, Softcover reprint of the original 1st ed. 1998): Enrico Mihich, Carlo Croce The Biology of Tumors (Paperback, Softcover reprint of the original 1st ed. 1998)
Enrico Mihich, Carlo Croce
R4,806 Discovery Miles 48 060 Ships in 7 - 11 working days

The Ninth Annual Pezcoller Symposium entitled "The Biology of Tumors" was held in Rovereto, Italy, June 4-7, 1997. It focused on the genetic mechanisms underlying het erogeneity of tumor cell populations and tumor cell differentiation, on interactions be tween tumor cells and cells of host defenses, and the mechanisms of angiogenesis. With presentations at the cutting edge of progress and stimulating discussions, this symposium addressed issues related to phenomena concerned with cell regulation and cell interactions as determined by activated genes through the appropriate and timely media tion of gene products. Important methodologies that would allow scientists to measure dif ferentially genes and gene products and thus validate many of the mechanisms of control currently proposed were considered, as were the molecular basis of tumor recognition by the immune system, interactions between cells and molecular mechanisms of cell regula tion as they are affected by or implemented through these interactions. The molecular and cellular mechanisms of tumor vascularization were also discussed. It was recognized that angiogenesis provides a potential site of therapeutic intervention and this makes it even more important to understand the mechanisms underlying it. We wish to thank the participants in the symposium for their substantial contribu tions and their participation in the spirited discussions that followed. We would also like to thank Drs."

Phospholipid Metabolism in Apoptosis (Paperback, Softcover reprint of the original 1st ed. 2004): Peter J. Quinn, Valerian E.... Phospholipid Metabolism in Apoptosis (Paperback, Softcover reprint of the original 1st ed. 2004)
Peter J. Quinn, Valerian E. Kagan
R4,806 Discovery Miles 48 060 Ships in 7 - 11 working days

The last few years have witnessed an explosion of both interest and knowledge about apoptosis, the process by which a cell actively commits suicide. The number of publications on the topic has increased from nothing in the early 1980s to more than 10,000 papers annually today. It is now well recognized that apoptosis is essential in many aspects of normal development and is required for maintaining tissue homeostasis. The idea that life requires death seems somewhat paradoxical, but cell suicide is essential for an animal to survive. For example, without selective destruction of "non-self" T cells, an animal would lack immunity. Similarly, meaningful neural connections in the brain are whittled from a mass of cells. Further, developmental cell remodeling during tissue maturation involves programmed cell death as the major mechanism for functional and structural safe transition of undifferentiated cells to more specialized counterparts. Apoptosis research, with roots in biochemistry, developmental and cell biology, genetics, and immunology, embraces this long-ignored natural law. Failure to properly regulate apoptosis can have catastrophic consequences. Cancer and many diseases (AIDS, Alzheimer's disease, Parkinson's disease, heart attack, stroke, etc. ) are thought to arise from deregulation of apoptosis. As apoptosis emerges as a key biological regulatory mechanism, it has become harder and harder to keep up with new developments in this field.

Dendritic Cells in Fundamental and Clinical Immunology - Volume 3 (Paperback, Softcover reprint of the original 1st ed. 1997):... Dendritic Cells in Fundamental and Clinical Immunology - Volume 3 (Paperback, Softcover reprint of the original 1st ed. 1997)
Paola Ricciardi- Castagnoli
R5,332 Discovery Miles 53 320 Ships in 7 - 11 working days

These proceedings contain selected contributions from the participants to the Fourth International Symposium on Dendritic cells that was held in Venice (Lido) Italy, from Oc tober 5 to 10, 1996. The symposium was attended by more than 500 scientists coming from 24 different countries. Studies on dendritic cells (DC) have been greatly hampered by the difficulties in preparing sufficient cell numbers and in a reasonable pure form. At this meeting it has been shown that large quantities of DC can be generated from precursors in both mice and humans, and this possibility has enormously encouraged studies aimed to characterize DC physiology and DC-specific genes, and to employ DC therapeutically as adjuvants for im munization. The possibility of generating large numbers of autologous DC that can be used in the manipulation of the immune response against cancer and infectious diseases has tremendously boosted dendritic cell research and the role of DC in a number of medi cal areas has been heatedly discussed."

Spine-Laminated (Poster): Vincent Perez Spine-Laminated (Poster)
Vincent Perez
R304 Discovery Miles 3 040 In stock

Our new poster, The Spine, covers the anatomy of the human vertebral column and its support structures with beautiful and intricate illustrations, newly designed by accomplished anatomical artist Vincent Perez. Thorough coverage includes multiple views of the vertebral column, as well as muscles, joints, and nerves, with labels for reference. From teachers and students of anatomy, to medical professionals and therapists, this poster is the perfect complement to your medical study or practice. It s also a great companion to our new, portable guide, The Spine "

McMinn's Color Atlas of Head and Neck Anatomy (Hardcover, 5th Revised edition): Bari M. Logan, Patricia Reynolds, Scott... McMinn's Color Atlas of Head and Neck Anatomy (Hardcover, 5th Revised edition)
Bari M. Logan, Patricia Reynolds, Scott Rice, Ralph T. Hutchings
R1,484 Discovery Miles 14 840 Ships in 10 - 15 working days

Originally published as part of the McMinn anatomy atlas family, McMinn's Color Atlas of Head and Neck Anatomy remains the only large format photographic atlas of the human head and neck, incorporating outstanding dissections, osteology, radiographic and surface anatomy images. It is the ideal study aid or trusted reference for the range of students and practitioners who require a detailed understanding of the head and neck, including those in dentistry, radiology and surgery. Dissections are accompanied by concise notes and commentaries, as well as orientational artworks to help readers locate the structure on the body. Dental anaesthesia information and important quick reference lists are also incorporated in appendices at the back of the book. This updated fifth edition offers increased clinical relevance and features an entirely new chapter on Imaging of the Head and Neck, reflecting the very latest modalities and techniques. It also comes with the complete, enhanced eBook for the first time. Increased clinical relevance - helps translate traditional anatomy into current clinical practice All new state-of-the-art clinical imaging - including: 3T MRI of the brain with tractography Cone-beam CT assessment of the jaws and middle ear Concise notes and commentaries for every dissection Dedicated dental section Access to complete downloadable eBook version via Expert Consult, with bonus enhancements - including: Over 180 additional figures - expands the imaging of normal and developmental structures and highlights common and clinically important variations, anomalies, defects and diseases Interactive question bank - over 150 multiple choice questions to aid exam preparation and check your understanding

Human Retroviral Infections - Immunological and Therapeutic Control (Paperback, Softcover reprint of the original 1st ed.... Human Retroviral Infections - Immunological and Therapeutic Control (Paperback, Softcover reprint of the original 1st ed. 2002)
Kenneth E. Ugen, Mauro Bendinelli, Herman Friedman
R4,338 Discovery Miles 43 380 Ships in 7 - 11 working days

The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time, a tremendous amount of information has been obtained about the virus. Although recent drug regimens have been useful in significantly lowering viral loads and perhaps maintaining an asymptomatic state among individuals infected with HIV-1, an established "cure" for AIDS eludes us. In addition, the effective drug therapies are very expensive, and are not available to infected people in the third world, where greater than 90% of new infections occur. Furthermore, the development of viral resistance against the drug therapies is an additional concern. Despite extensive study, no effective vaccine has been developed. One of the problems in developing an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelop glycoprotein, to undergo amino acid hypervariability.

Advances in Cell Biology (Paperback, Softcover reprint of the original 1st ed. 1971): David M. Prescott Advances in Cell Biology (Paperback, Softcover reprint of the original 1st ed. 1971)
David M. Prescott
R3,629 Discovery Miles 36 290 Ships in 7 - 11 working days

Advances in Cell Biology has been initiated as a continuing, multi-volume series to report on the progress of a wide spectrum of problems of cell structure and cell function. Jn arranging these volumes individual contributors are asked not only to review the major new information, but especially to present the state of a given problem or area by discussing the current central issues, speculations, concepts, hypotheses, and technical problems. We intend, in addition, that these volumes will not be concerned with comprehensive reviews of the recent literature but will consist rather of presentations of an interpretive and integrative nature, based on selection of major research advances. It is our aim that these volumes should provide the means whereby cell biologists may keep themselves reasonably well informed about the current progress in research areas in cell biology in which they are not immediately or directly involved themselves. The articles, nevertheless, are expected to bring into focus the experimental objectives of the specialists in a given research area. D. M.P. L. G. E.M. vii Contents Contributors v Preface vii 1 1. The Regulation of DNA Synthesis in Eukaryotes James Douglas Watson 2. D.RNA Containing Ribonucleoprotein Particles and Messenger RNA Transport 47 G. P. Georgiev and 0. P. Samarina Recent Developments in the Synchronization of 3. Tetrahymena Cell Cycle 111 Eric Zeuthen 153 4. Repetitious DNA Christopher Bostock 5. Mitosis 225 R. Bruce Nicklas Specific Enzyme Production in Eukaryotic Cells 299 6."

Lippincott's Pocket Neuroanatomy (Paperback): Douglas J. Gould Lippincott's Pocket Neuroanatomy (Paperback)
Douglas J. Gould
R748 Discovery Miles 7 480 Ships in 10 - 15 working days

"Lippincott's Pocket Neuroanatomy "is a go-to reference, review, and study tool for neuroanatomy and neuroscience with a strong focus on high-yield topics and presentation. It presents the essential information needed for course and board exam review in a concise, quick-reference format with tables, full-color images, and bullet-point text. The book contains multiple features identifying the clinical significance of concepts, as well as mnemonics to aid in the retention of facts. An index of terms provides easy access to facts on all neuroanatomical structures and pathways. This pocket-sized reference intuits how students typically study for exams and provides highly distilled content in one easily portable source. It is ideal for medical, dental, allied health, and graduate school students and appropriate for courses in nursing, pre-pharmacy, pre-med, and kinesiology."
Features include: "An introductory chapter on terminology and orientation to provide a concise overview of conceptsClinically significant facts for practical applicationConsistent presentation of information including descriptions of structures, connections, pathways, and functionsLearning aids such as mnemonics and analogies to help you remember important factsA complete index of terms for quick reference

Atlas of Fetal Sectional Anatomy - With Ultrasound and Magnetic Resonance Imaging (Paperback, Softcover reprint of the original... Atlas of Fetal Sectional Anatomy - With Ultrasound and Magnetic Resonance Imaging (Paperback, Softcover reprint of the original 1st ed. 1986)
Glenn Isaacson, Marshall C. Mintz, Edmund S Crelin
R2,205 Discovery Miles 22 050 Ships in 7 - 11 working days

The fetal period of human growth and development has become an area of intense study in recent years, due in large part to the development of diagnostic ultrasound. More than 2,000 articles have been published in the last five years describing anatomy and pathology in utero, as reflected in sonographic images. Yet, no stan dard reference exists to correlate these images with fetal gross anatomy and at tempts to draw parallels from adult structure have often led to false assumptions. The dictum "the newborn is not a miniature adult" is all the more valid for the fetus. This text aims to provide a comprehensive reference for normal sectional anat omy correlated with in utero ultrasound images. In addition, magnetic resonance images of therapeutically aborted or stillborn fetuses are paired with similar gross sections to serve as a foundation upon which current in vivo studies may build. Lastly, a miscellaneous section illustrates several anatomic points useful in the understanding of fetal anatomy. These points include the changing anatomy of the fetal brain during gestation and the anatomy of the meninges, the fetal heart, and ductus venosus. It is our hope that this atlas will provide a clear picture of fetal anatomy, rectify some of the confusion which exists in antenatal diagnosis, and stimulate further interest in fetal development."

Microscopy, Immunohistochemistry, and Antigen Retrieval Methods - For Light and Electron Microscopy (Paperback, Softcover... Microscopy, Immunohistochemistry, and Antigen Retrieval Methods - For Light and Electron Microscopy (Paperback, Softcover reprint of the original 1st ed. 2002)
M. A. Hayat
R6,001 Discovery Miles 60 010 Ships in 7 - 11 working days

Histochemistry deals with the activities of chemical components in cells, and immunohistochemistry addresses the function of cell types in tissue or organs, such as those leading to acceptance or rejection of grafts or organs. This book is a methods volume focusing on antigen retrieval, particularly methods used in disease-related antigens. Because the book is a methods volume and a lab manual, it will have an audience of pathologists, biochemists, and lab technicians.

Cell Impairment in Aging and Development (Paperback, Softcover reprint of the original 1st ed. 1975): V Cristofalo Cell Impairment in Aging and Development (Paperback, Softcover reprint of the original 1st ed. 1975)
V Cristofalo
R2,697 Discovery Miles 26 970 Ships in 7 - 11 working days

lar aging, to which this model contributes, has grown. Apart from reports on work in this almost "classical" diploid cell system, the symposium presents studies using different biological systems with results that have been rewarding as information is obtained on patterns of change that are common to more than one experimental system. Indeed, in recent years much more has been learned about the fate of all different types of intermitotic and postmitotic cells in situ. The symposium has also presented contributions dealing, not directly with aging but with early ontogeny; such information on early developmental changes should certainly shed light on some of the mechanisms involved in aging. We are cognizant of the fact that environmental influences resulting from the complexities of modern civilization may have results that only occur much later, and profoundly affect the lifespan of the organism. There remain, of course, many unanswered questions. Whether there is "physiological" as opposed to "pathological" aging; whether "old" cultures living in unchanged, although not exhausted, medium, are degenerating, not aging; what is involved when "old" fragment cultures regenerate after excision by filling the wound with "young" cells; why some tumor cells in vivo as well as in vitro die while others live; all are questions eserving of our attention.

Mammal Phylogeny - Mesozoic Differentiation, Multituberculates, Monotremes, Early Therians, and Marsupials (Paperback,... Mammal Phylogeny - Mesozoic Differentiation, Multituberculates, Monotremes, Early Therians, and Marsupials (Paperback, Softcover reprint of the original 1st ed. 1993)
Frederick S. Szalay, Michael J. Novacek, Malcolm C. McKenna
R3,385 Discovery Miles 33 850 Ships in 7 - 11 working days

The roots of this book and its sister volume, Mammal Phylogeny: Placenta/so go back to discussions and plans, shelved for a while, between F. S. Szalay and W. P. Luckett during the international and multidisciplinary symposium on rodent evolution sponsored by NATO, July 2-6, 1984, in Paris. That conference, orga nized by W. P. Luckett and J. -L. Hartenberger, the proceedings of which were published in 1985, proved an inspiring experience to all of the participants, as this was repeatedly expressed both during and after the meetings. In addition to issues relating to rodents, general theoretical topics pertaining to the evolutionary biol ogy and systematics of other groups of mammals regularly surfaced during the presentations and discussions. M. J. Novacek, who was also a participant in the rodent symposium, shared with Luckett and Szalay the enthusiasm acquired there, and he also expressed strong interest for a meeting on mammal evolution with a general focus similar to that of the rodent gathering. In 1988, Szalay and Luckett, after having planned in detail a program, direc tion, and core list of participants, were awarded a $30,000 grant by the Alfred P. Sloan Foundation through the Research Foundation of the City University of New York. The grant was contingent upon obtaining additional funds sufficient to assure that the symposium would be held. Raising the remaining funds proved to be a problem.

Circulatory System & Arterial Hypertension - Experimental Investigation, Mathematical & Computer Simulation (Hardcover):... Circulatory System & Arterial Hypertension - Experimental Investigation, Mathematical & Computer Simulation (Hardcover)
Ludmila N. Ivanova, Alexander M Blokhin, Arcady L. Markel, Evgenia V. Mishchenk
R4,164 Discovery Miles 41 640 Ships in 10 - 15 working days

This book is a multidisciplinary book in which the problem on hypertensive disease is analysed from different points of view by physicists, mathematicians, biologists. Topics discussed include a review on genetic and physiological mechanisms of arterial hypertension; descriptions of various approaches to mathematical modelling of the system for controlling blood circulation and blood flow in a vessel; a survey existing models of hemodynamics and description of an approach to numerical modelling of the blood flow in the human cardiovascular system; and a software developed for visual creation and simulation of modular mathematical models of the biological systems.

Drugs, Stress and Human Function (Paperback): Richard Almon, Debra DuBois, Amanda Almon Drugs, Stress and Human Function (Paperback)
Richard Almon, Debra DuBois, Amanda Almon
R2,288 Discovery Miles 22 880 Ships in 7 - 11 working days

"Drugs, Stress and Human Function" is written for non-major, general education courses in human biology. Based on the premise that students will most readily and effectively learn about what interests and relates to them, the book explores biology from the perspective of health-related issues and experiences that are relevant to all.
Building on a nature versus nurture approach, the book presents an integrated view of all major organ systems and explains human biology using real and relevant topics, such as reproduction, stress, nutrition, aging, disease, and drugs.
In contrast to many other textbooks in the field, "Drugs, Stress and Human Function" is written in a clear, concise manner, free of the scientific jargon that is often inaccessible to students. The material emphasizes how it works conveying important concepts in an understandable and meaningful way and using simple, straightforward illustrations to clarify information and enhance student learning.
The book begins with an overview of the human body. Students then learn about biology at the molecular and cellular levels. Subsequent chapters move the study of biology from the minute to the experiential. The topics addressed include:
- Barriers of the Body
- The Brain
- The Immune System
- Infections and Cancer
- Pain
"Drugs, Stress and Human Function" is an excellent text for introductory courses in biology.
Richard Almon earned his B.S. in Psychology and Mathematics, his M.S. in Physiology, and his Ph.D in Physiology and Biochemistry at the University of Illinois. Dr. Almon is an active researcher with academic appointments in the Departments of Biological Sciences and Pharmaceutical Sciences and the New York State Center of Excellence in Bioinformatics and Life Sciences at the State University of New York, Buffalo. He has over 30 years of experience teaching non-major biology courses such as pharmacology and nutrition, as well as graduate level endocrinology. His research specialization is in systems biology, an interdisciplinary area that integrates a number of disciplines ranging from physiology to molecular biology. Dr. Almon has over 120 scientific publications to his credit.
Debra DuBois earned her B.S. in Human Genetics at McGill University and her M.S. and Ph. D. in Biological Sciences at the State University of New York, Buffalo. Dr. DuBois holds academic appointments in the departments of Biological Sciences and Pharmaceutical Sciences at the university. In conjunction with Dr. Richard Almon, she has more than 90 scientific publications to her credit. Her work investigates phenomena such as autoimmunity, gravitational biology, muscular dystrophy, fetal metabolic programming, arthritis, and diabetes from the genetic to the systems level.
Amanda S. Almon is a certified Medical Illustrator. She earned her B.F.A. in Medical Illustration at the Rochester Institute of Technology, and her M.F.A. at the University of Michigan, where she completed the AMI accredited program in Biomedical Illustration. She is an associate professor and the Head of Biomedical Art at the Cleveland Institute of Art, and an adjunct professor of anatomy at Case Western Reserve University.

Biology of the Integument - 2 Vertebrates (Paperback, Softcover reprint of the original 1st ed. 1986): J. Bereiter-Hahn, A. G... Biology of the Integument - 2 Vertebrates (Paperback, Softcover reprint of the original 1st ed. 1986)
J. Bereiter-Hahn, A. G Matoltsy, K.S. Richards
R3,710 Discovery Miles 37 100 Ships in 7 - 11 working days

The integument plays an important role in the survival of meta zoans by separating and protecting them from a hostile environ ment. Its function ranges from protection against injury and in fection, participation in the regulation of body temperature and water balance, to respiratory activity, monitoring of the environ ment and production of signals related to behaviour. All these result from specific structural, biochemical and physiological properties of intra-and extracellular components of the integu ment. Thus its characterization can be best accomplished by a multidisciplinary approach with authors specialized in different fields of science. This multi-author book, in two volumes, provides an up-to date survey of the literature. The first volume deals with the integument of invertebrates, the second with that of vertebrates, both organized primarily on a phylum basis. As the level of knowledge on the integument of phyla differs considerably, the information provided is correspondingly either limited or con densed. For some of the smaller groups of invertebrates little information is available, as often only a few electron micrographs are to be found in the literature ; on the other hand, from the large body of knowledge existing for vertebrates, particularly for mammals, no complete overview can be provided, but publica tions giving access to further information have been reviewed critically.

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