This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of "clock" gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.

Titles in the Pocket Tutor series give practical guidance at a highly-affordable price on subjects that medical students, foundation doctors and a range of other practitioners need help with 'on the go'. The highly-structured, bite-size content helps novices combat the fear factor associated with day-to-day clinical training, and provides a handy reference that students and junior doctors can carry with them at all times. Pocket Tutor Surface Anatomy is an indispensable guide to a subject that is increasingly important on today's medical courses and a crucial preamble to the study of clinical skills and procedures, indeed to the study of all medicine and surgery. Key Features: Logical, sequential content: introduction to the principles of living anatomy, then chapters devoted to individual regions, with each sub-region illustrated by specially commissioned photographs featuring ghosted underlying structures Each region (e.g. Upper Limb) described in a consistent manner: Introduction & Core Features which focuses on Arteries & Veins, Nerves & Dermatomes and Core Landmarks; then for each subregion (e.g. Shoulder & Arm) Bones Joints & Ligaments, Muscles Tendons & Regions, and Neurovascular & Lymph Changes to second edition: New chapter on paediatric surface anatomy highlights the anatomical differences in children and how they vary during development 15+ new and improved radiological images match surface markings to underlying structures More sites of nerve injury, surgical incision lines and normal/pathological variation added to surface anatomy photos correlate anatomical landmarks to clinical practice Chapters reordered from head to toe to provide a more logical and accessible ordering of content Previous edition (9781907816178) published 2012.

This book bridges the gap between a clinician's and material scientists' knowledge by elucidating upon the different biomaterials used in anatomical systems and how those materials react to the human body. It explores both established and future prospective of biomaterial types/designs, and considerations in material selection and synthesis, to guide students from non-clinical background in understanding the relations of material science and the human body.

This is the first textbook to comprehensively cover the experimental methods used in biomechanics. Designed for graduate students and researchers studying human biomechanics at the whole-body level, the book introduces readers to the theory behind the primary data collection methods and primary methods of data processing and analysis used in biomechanics. Each individual chapter covers a different aspect of data collection or data processing, presenting an overview of the topic at hand and explaining the math required for understanding the topic. A series of appendices provide the specific math that is required for understanding the chapter contents. Each chapter leads readers through the techniques used for data collection and processing, providing sufficient theoretical background to understand both the how and why of these techniques. Chapters end with a set of review questions, and then a bibliography which is divided into three sections (cited references, specific references, and useful references). Provides a comprehensive and in depth presentation on methods in whole-body human biomechanics; First textbook to cover both collection and processing in a single volume; Appendices provide the math needed for the main chapters.

The fifth edition of Lachman's Case Studies in Anatomy is a thoroughly revised edition of a popular collection of 50 anatomical cases. Each chapter starts with a clinical case presentation, followed by diagnosis and therapy and then an extensive discussion of the anatomy that is relevant to the case. The patient presentations provide the history and physical examination findings in a format consistent with that which the student will utilize in clinical training. Diagnostic and therapeutic procedures that are discussed have been brought up-to-date and are consistent with current medical practice. Cases represent clinical encounters required in clerkship curricula. This should allow students to draw from this book throughout their four years in medical school. The scope of the book has been expanded to include embryological development by including three new cases of developmental abnormalities. Many new figures and have included many diagnostic images including radiographs, CT scans, MRIs and ultrasounds. To help the reader feel confident that the major anatomical points have been mastered, review questions and answers have been added at the end of each unit.

This revision aid is of great practical benefit to all radiology trainees studying for their professional examinations. The carefully structured questions and answers enable trainees to undertake a systematic assessment of their knowledge; they also highlight areas where additional study is required. It is developed to complement its highly illustrated parent text, Applied Radiological Anatomy (Cambridge, 1999); but both books can be used together or independently of one another. The questions posed within are relevant and useful for radiology trainees worldwide.

Unique among neuroanatomical texts ... This is no dry compilation of facts but an attention-rivetting discussion of neurological organization.' Annals of Internal Medicine on the 2nd edition.

This multi-authored, multi-institutional, and multi-specialty based text is designed to inform and refresh practitioners who perform facial cosmetic surgery. Divided into three distinct sections for ease of use, the first section focuses exclusively on localized anesthesia for each region of the head and neck. Chapters focus on the techniques that best affect these regions with a chapter closing the first section, on managing potential anesthetic complications. The second section covers the regional anatomy of the face by offering high definition photos of cadaver dissections and anatomic illustrations to highlight pertinent muscle and bone structures. The third and final section combines the skills detailed in the first two sections and applies them to a variety of surgical, cosmetic procedures. In an era of high demand for aesthetic procedures, this text provides a practical and comprehensive look at facial cosmetic surgery to ensure practitioners have the best information available for treating their patients. The editors have extensive academic experience and have authored multiple scientific publications, while the contributions included in the text have been written by experts and leaders in the field. Applied Head and Neck Anatomy for the Facial Cosmetic Surgeon is written for a multi-disciplinary audience including oral & maxillofacial surgeons, plastic surgeons, otolaryngologists, cosmetic surgeons, and dentists.

In Functional Anatomy of the Pelvis and the Sacroiliac Joint author and respected bodywork specialist John Gibbons looks at one of the most important areas of the body: the pelvis and the sacroiliac joint. He takes readers on a fascinating journey of enlightenment, teaching us to recognize pain and dysfunctional patterns that arise from the pelvic girdle. Gibbons addresses key issues such as: * The walking/gait cycle and its relationship to the pelvis * Leg length discrepancy and its relationship to the kinetic chain and the pelvis * The laws of spinal mechanics * The relationship of the hip joint, gluteal muscles, lumbar spine to the pelvis * Sacroiliac joint screening In addition, he provides step-by-step techniques to identify and correct a number of impaired patterns as well as functional exercises for the pelvis that promote recovery.

This book discusses major changes in our understanding of the most prevalent non-orthopedic, sports-related condition - overtraining syndrome (OTS), arguing that it should be considered as the manifestation of burnout in athletes, rather than simply the result of excessive training. While the chronic adaptations of the cardiovascular and musculoskeletal systems to exercise are well documented, those of the endocrine system are less well known, and adaptations of the hormonal ranges for athletes are yet to be determined. There is also a lack of standardized diagnostic criteria, consistent assessment methods and biomarkers. This book offers a systematic review of the hormonal aspects of overtraining syndrome, and a comparison with sports-related syndromes triggered by chronic deprivation of different sorts, including the female athlete triad (and its derivative, RED-S) and burnout syndrome of the athlete (BSA). It demonstrates that these conditions, although studied separately from each other, may all be different manifestations of the same condition, leading to 'maladaptive' (dysfunctional forced adaptations to a hostile environment) changes in response to chronic depletion of energy and mechanisms of repair, causing multiple dysfunctions. The author proposes that OTS/Paradoxical Deconditioning Syndrome (PDS), RED-S/TRIAD and BSA are parts of a same condition, or at least a group of similar conditions. Further, the book offers a chronological overview of OTS, based on preliminary research. Given its broad scope, this concise reference book will appeal to a range of health professionals. It allows readers, including those without a strong academic background, to gain a systematic understanding of OTS.

A knowledge of anatomy has always played a vital role in medicine, and is especially important in the everyday practice of anaesthesia. This 2002 text presents the core anatomical knowledge required for the Primary and Final FRCA examinations in a simple and straightforward manner. Adopting the philosophy of the examination itself, where candidates are often required to reproduce simple line drawings to illustrate the depth of their knowledge, the many illustrations in the book are clear and easy to understand at a glance. The illustrations are accompanied by explanatory text throughout and for each anatomical region, sample examination questions are included which follow the format of those asked in the examinations. This book will interest anaesthesia Primary and Final candidates, as well as providing a valuable quick reference for busy anaesthetists at all levels of experience.

How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state-dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley

The Understanding the Hand & Wrist chart presents an in-depth look at the structure of the wrist and hand. The main image shows the left and right hands and wrists with musculature and ligaments. Smaller views illustrate the bones and ligaments. Heavy cover stock with protective varnish for durability.

The Understanding the Stomach chart presents an overview of a major component of the digestive system. The internal structure of the stomach and stomach lining are covered, as well as common disorders. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

In this book, experts in the field discuss the latest research in developmental neuroendocrinology. Given that the hypothalamus is the center of neuroendocrine activity, the reader will learn about the molecular specification of hypothalamic cells, developmental modulators and epigenetic factors influencing hypothalamic development, and the development of neuroendocrine circuits. Each chapter provides a concise review of the current and future perspectives in developmental neuroendocrinology. Important insights into state-of-the-art techniques applied to functional circuit tracking, lineage tracing of hypothalamic cells, and the identification of genes altered through epigenetic mechanisms are also provided. Given its scope, the book will appeal to all students and researchers who are eager to understand the processes involved in hypothalamus development and the establishment of neuroendocrine circuits. This is the ninth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series* that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. *Volumes 1-7 published by Wiley.

Featuring classic illustrations by Peter Bachin, this chart shows nerves in the body, brain, midbrain, medulla oblongata, and spinal cord. Spinal meninges, intercostal nerves, and sagittal section of female pelvis are also shown.

Featuring more than 85 vibrant, fully annotated charts-19 new to this edition-this updated fourth edition of Diseases and Disorders: The World's Best Anatomical Charts is a perfect quick reference for medical and nursing students and an ideal visual aid for patient education. Printed on oversized, cardstock pages and compiled in a convenient, 10" x 12" spiral-bound volume with a laminated cover, these full-color charts created by some of the world's best medical illustrators illustrate and explain common diseases and disorders of the brain; heart; GI tract; eye and ear; endocrine, muscular, skeletal, reproductive, and respiratory systems; dental diseases; infectious diseases; healthy lifestyle issues; and cancer. Nineteen new charts cover Schizophrenia, Ovarian Cancer, Multiple Myeloma, Liver Cancer, Pancreatic Cancer, Prostate Cancer, Heart Failure, Peripheral Artery Disease, UC/Crohn's Disease, Irritable Bowel Syndrome, Age-Related Macular Degeneration, and more. All charts have been reviewed and updated. Medical terminology and easy-to-understand supporting text are printed directly on each chart. Every chart depicts an aspect of human anatomy, physiology, and disease presented in a clear, visual presentation. The book is ideal as a review resource or quick reference for studying human anatomy or for patient consultation and education.

Providing the ocular anatomy and physiology content needed for a thorough comprehension of this complex field, Clinical Anatomy and Physiology of the Visual System, 4th Edition, offers a solid foundation for recognizing and understanding specific clinical situations and how they relate to anatomic structure. This concise, well-referenced resource covers the clinical anatomy of the eye, its adnexa and visual pathways, and histologic information-the information you need for success in coursework, certification exams, and clinical practice. Features vivid, full-color illustrations that help you visualize the clinical anatomy of the eye along with the cellular physiology behind diseases and disorders of the visual system. Emphasizes clinical application throughout, helping you better understand the processes that occur in disease and dysfunction. Clinical Comment sections offer a unique focus on clinical situations, conditions, diseases, and treatments. Contains new OCT, OCTA, MRI, and CT images that demonstrate clinical views of ocular anatomy. OCT technology is incorporated to describe the retinal layers, newly described anatomical components of the vitreous, corneal and anterior chamber angle anatomy, and the choroidal and retinal vasculature. Covers current topics such as genes essential in eye development, scleral and choroidal changes occurring with myopia progression, limbal stem cells, age-related macular degeneration and VEGF therapies, and microinvasive glaucoma surgical procedures. Includes updated concepts and terminology: Edinger Westfall preganglionic cells, sensory innervation to the cornea, knees of Wilbrand, intrinsically photosensitive retinal ganglion cells, and more. Provides expert coverage by a practicing optometrist, giving you a practical framework for recognizing and understanding clinical situations, problems, and treatments. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

There's a silent epidemic in western civilization, and it is right under our noses. Our jaws are getting smaller and our teeth crooked and crowded, creating not only aesthetic challenges but also difficulties with breathing. Modern orthodontics has persuaded us that braces and oral devices can correct these problems. While teeth can certainly be straightened, what about the underlying causes of this rapid shift in oral evolution and the health risks posed by obstructed airways? Sandra Kahn and Paul R. Ehrlich, a pioneering orthodontist and a world-renowned evolutionist, respectively, present the biological, dietary, and cultural changes that have driven us toward this major health challenge. They propose simple adjustments that can alleviate this developing crisis, as well as a major alternative to orthodontics that promises more significant long-term relief. Jaws will change your life. Every parent should read this book.

A visit to a physician these days is cold: physicians spend most of their time typing at computers, making minimal eye contact. Appointments generally last only a few minutes, with scarce time for the doctor to connect to a patient's story, or explain how and why different procedures and treatments might be undertaken. As a result, errors abound: indeed, misdiagnosis is the fourth-leading cause of death in the United States, trailing only heart disease, cancer, and stroke. This is because, despite having access to more resources than ever, doctors are vulnerable not just to the economic demand to see more patients, but to distraction, burnout, data overload, and their own intrinsic biases. Physicians are simply overmatched. As Eric Topol argues in Deep Medicine, artificial intelligence can help. Natural-language processing could automatically record notes from our doctor visits; virtual psychiatrists could better predict the risk of suicide or other mental health issues for vulnerable patients; deep-learning software will make every physician a master diagnostician; and we could even use smartphone apps to take our own medical "selfies" for skin exams and receive immediate analysis. . On top of that, the virtual smartphone assistants of today--Alexa, Siri, Cortana--could analyze our daily health data to reduce the need for doctor visits and trips to the emergency room, and support for people suffering from asthma, epilepsy, and heart disease. By integrating tools like these into their daily medical practice, doctors would be able to spend less time collecting and cataloging information, and more time providing thorough, intimate, and meaningful care for their patients, as no machine can. Artificial intelligence can also help remedy the debilitating cost of healthcare, both for individuals and the economy writ large. The medical sector now absorbs 20 percent of the US gross domestic product--it is largest sector by dollars and jobs. And it's very inefficient. Take the cost of medical scans: There are over 20 million medical scans performed in the US every day, and an MRI, for example, costs hundreds to thousands of dollars. AI could process 260 million medical scans (more than 2 weeks' worth) in less than 24 hours for a cost of only $1000. We pay billions and billions of dollars for the same work today. The American health care system needs a serious reboot, and artificial intelligence is just the thing to press the restart button. As innovative as it is hopeful, Deep Medicine ultimately shows us how we can leverage artificial intelligence for better care at lower costs with more empathy, for the benefit of patients and physicians alike.

Written and edited by expert surgeons in collaboration with a world-renowned anatomist, this exquisitely illustrated reference consolidates surgical, anatomical and technical knowledge for the entire human body in a single volume. Part of the highly respected Gray's 'family,' this new resource brings to life the applied anatomical knowledge that is critically important in the operating room, with a high level of detail to ensure safe and effective surgical practice. Gray's Surgical Anatomy is unique in the field: effectively a textbook of regional anatomy, a dissection manual, and an atlas of operative procedures - making it an invaluable resource for surgeons and surgical trainees at all levels of experience, as well as students, radiologists, and anatomists. Brings you expert content written by surgeons for surgeons, with all anatomical detail quality assured by Lead Co-Editor and Gray's Anatomy Editor-in-Chief, Professor Susan Standring. Features superb colour photographs from the operating room, accompanied by detailed explanatory artwork and figures from the latest imaging modalities - plus summary tables, online videos (intra-operative and cadaveric), self-assessment questions, and case-based scenarios - making it an ideal reference and learning package for surgeons at all levels. Reflects contemporary practice with chapters logically organized by anatomical region, designed for relevance to surgeons across a wide range of subspecialties, practice types, and clinical settings - and aligned to the requirements of current trainee curricula. Maximizes day-to-day practical application with references to core surgical procedures throughout, as well as the 'Tips and Anatomical Hazards' from leading international surgeons. Demonstrates key anatomical features and relationships that are essential for safe surgical practice - using brand-new illustrations, supplemented by carefully selected contemporary artwork from the most recent edition of Gray's Anatomy and other leading publications. Integrates essential anatomy for robotic and minimal access approaches, including laparoscopic and endoscopic techniques. Features dedicated chapters describing anatomy of lumbar puncture, epidural anaesthesia, peripheral nerve blocks, echocardiographic anatomy of the heart, and endoscopic anatomy of the gastrointestinal tract - as well as a unique overview of human factors and minimizing error in the operating room, essential non-technical skills for improving patient outcomes and safety. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices - PLUS a wealth of BONUS content not found in the printed book.