The diagnosis and treatment of the diseases of the nose, paranasal sinuses and skull base have changed dramatically in the past few years, transforming rhinol ogy in one of most exciting and attractive medical fields. The increasing advance in this area has addressed the ENT physicians to keep up with the expanding information in the high tech area of sinus surgery and its expansion into skull base surgery. The intention of this book is to present in a unique way basic information on Anatomy, Endoscopy, Rhinomanometry, Imaging, Allergy, Nasosinus Infection, and Polyposis followed by by clinical and surgical chapters written by some of the most experienced rhinosurgeons around the world. We belive that this book will be of value for all levels of Otolaryngology, from house officers to experienced surgeons and, although principally for Otolaryngologists, Radiologists, Patholo gists, Maxillofacial surgeons, Ophthalmologists, Neurosurgeons, and Infectious Diseases Specialists may find the book of value because of its overlap with their interests. We would like to show that, both from the technical and conceptual points of view, success can be achieved using different techniques and philosophies. Cer tainly, both endoscopic instrumentation and the surgical microscope have proved to be of great assistance in nasal and sinus surgery, and now image systems are providing further progress.

Just because A&P is complicated, doesn't mean learning it has to be. Anthony's Textbook of Anatomy & Physiology, 21st Edition uses reader-friendly writing, visually engaging content, and a wide range of teaching and learning support to ensure classroom success. Focusing on the unifying themes of structure and function and homeostasis, author Kevin Patton uses a very conversational and easy-to-follow narrative to guide you through difficult A&P material. The new edition of this two-semester text has been updated to ensure you have a better understanding of how the entire body works together. In addition, you can connect with the textbook through a number of free electronic resources, including , an electronic coloring book, 3D animations, and more! Conversational writing style at a 11.7 reading level (the lowest available for 2-semester A&P books) makes text engaging and easy to understand. Updated Genetics chapter includes important advancements in that field. Updated content on osmosis revised to make it more simple and accurate. More than 1,400 full-color photographs and drawings illustrate the most current scientific knowledge and bring difficult concepts to life. Includes a unique color key to show color scheme that is used consistently throughout the book (for example, bones are off white, enzymes are lime green, nucleus is purple). UNIQUE! Consistent unifying themes, such as the Big Picture and Cycle of Life sections in each chapter, help you comprehend the interrelation of body systems and how the structure and function of these change in relation to age and development. Numerous feature boxes including: Language of Science and Language of Medicine, Mechanisms of Disease, Health Matters, Diagnostic Study, FYI, Sport and Fitness, and Career Choices provide interesting and important sidebars to the main content. Quick Check Questions reinforce learning by prompting you to review what you've just read. Chapter outlines, chapter objectives and study tips begin each chapter. NEW! Integrative Unit Closers ties together content with integrative critical thinking questions. NEW! Additional and updated Connect It! boxes (renamed from A&P Connect) provide relevant "bonus" information for you to explore. NEW! All-new animations in the text and on Evolve companion site help you understand the reasoning and knowledge behind each answer and assist with recalling correct answers.

Human Anatomy and Physiology: Form, Function, and Homeostasis helps students understand the human body in terms of the structures and functions of various body systems. Clear and concise, the selected material provides descriptions of how major organ systems, individual organs, tissues, and cells interact to maintain homeostasis. The text establishes a conceptual framework for studying anatomy and physiology at the molecular, cellular, and systematic levels. The major chapters of the text include the integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, respiratory, digestive, urinary, and reproductive systems. Chapters that focus on physiology begin with case studies that highlight major concepts and progress to discussions of the major processes that regulate homeostasis. All chapters include a list of learning outcomes that are aligned with a collection of study questions. Many standard texts provide more information than can be covered, even in a standard, two-course progression. Human Anatomy and Physiology streamlines information and focuses on the most important aspects of human form and function in a no-frills, non-intimidating manner. The book is specifically designed for standard two-course sequences in anatomy and physiology, and is best suited to students who have completed a semester of biology.

This is by far the most exhaustive biography on Niels Stensen, anatomist, geologist and bishop, better known as "Nicolaus Steno". We learn about the scientist's family and background in Lutheran Denmark, of his teachers at home and abroad, of his studies and travels in the Netherlands, Belgium, France, Italy, Austria, Hungary, Bohemia and Germany, of his many pioneering achievements in anatomy and geology, of his encounters with Swammerdam, Malpighi and with members of the newly established Royal Society of London and the Accademia del Cimento in Florence, and with the philosopher Spinoza. It further treats Stensen's religious conversion. The book includes the full set of Steno's anatomical and geological scientific papers in original language. The editors thoroughly translated the original Latin text to English, and included numerous footnotes on the background of this bibliographic and scientific treasure from the 17th century.

This volume presents a series of protocols and methods, some of which are not widely used by researchers/practitioners, and will aid in the execution of different laboratory techniques. Forensic DNA Typing Protocols, Second Edition is arranged into a series of related chapters. Chapter 1-3 examines two different aspects of RNA analysis for body fluid identification. Chapters 4-7 focuses on the storage of biological materials and the extraction of DNA from hard tissues. Chapters 8-10 present methods for monitoring the quality of DNA extracts, and steps to aid in the purification of DNA. Chapters 11-16 talk about methods on non-standard markers, such as INDELs, Y chromosome STRs, and mitochondrial DNA. Detailed procedures and data analysis for phenotypes and ancestry are explored in Chapter 17-19. The last chapter (20) looks at the application of DNA typing to the identification of non-human material to species level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and thorough, Forensic DNA Typing Protocols, Second Edition, is a valuable resource for forensic specialists, researchers, and anyone interested in the field of forensic science.

Each new print copy of Anatomy & Physiology also includes Navigate 2 Advantage Access that unlocks a complete eBook, Study Center, homework and Assessment Center, and a dashboard that reports actionable data. World-Class Medical Content To properly assess and manage a patient, a prehospital provider must have a solid foundation in human anatomy and physiology. Anatomy & Physiology for the Prehospital Provider, Second Edition, uses a systemic approach to building this foundation. It begins by providing an overview of the basic systems of the human body and then explores each system in detail chapter by chapter, delivering a thorough discussion on the system's anatomy, physiology, and pathophysiology. With clear, accessible language and informative illustrations, the Anatomy & Physiology for the Prehospital Provider, Second Edition is an effective and engaging learning experience. Strong Application to Real-World EMS Progressive patient case studies evolve throughout every chapter, offering the learner genuine context for the application of the knowledge presented. This approach shows the learner how all of the information will be used to help patients in the field. The Second Edition content includes: New section on the basics of chemistry Expanded section on joints Expanded content on muscular physiology Updated illustrations Additional pathophysiology, including cellular injury

This volume expands on statistical analysis of genomic data by discussing cross-cutting groundwork material, public data repositories, common applications, and representative tools for operating on genomic data. Statistical Genomics: Methods and Protocols is divided into four sections. The first section discusses overview material and resources that can be applied across topics mentioned throughout the book. The second section covers prominent public repositories for genomic data. The third section presents several different biological applications of statistical genomics, and the fourth section highlights software tools that can be used to facilitate ad-hoc analysis and data integration. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible analysis protocols, and tips on troubleshooting and avoiding known pitfalls. Through and practical, Statistical Genomics: Methods and Protocols, explores a range of both applications and tools and is ideal for anyone interested in the statistical analysis of genomic data.

This volume presents techniques and recent developments in biochemical approaches to study glutamatergic neurotransmission. This book contains detailed discussions on tracing neuronal pathways, functional or spectroscopic imaging, optogenetic or pharmacological tools, and extracellular neurochemistry in experimental clinical models. The chapters cover topics such as: identification of glutamatergic neurons in a discrete brain area, tools to study dynamics of single ionotropic receptors, in vivo extracellular glutamate monitoring in preclinical research using biosensors, capillary electrophoresis and liquid chromatography, and potential brain glutamatergic clinical biomarkers in biofluids and tissues. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Biochemical Approaches for Glutamatergic Neurotransmission is a valuable resource for researchers studying glutamate neurochemistry.

This is by far the most exhaustive biography on Niels Stensen, anatomist, geologist and bishop, better known as "Nicolaus Steno". We learn about the scientist's family and background in Lutheran Denmark, of his teachers at home and abroad, of his studies and travels in the Netherlands, Belgium, France, Italy, Austria, Hungary, Bohemia and Germany, of his many pioneering achievements in anatomy and geology, of his encounters with Swammerdam, Malpighi and with members of the newly established Royal Society of London and the Accademia del Cimento in Florence, and with the philosopher Spinoza. It further treats Stensen's religious conversion. The book includes the full set of Steno's anatomical and geological scientific papers in original language. The editors thoroughly translated the original Latin text to English, and included numerous footnotes on the background of this bibliographic and scientific treasure from the 17th century.

Integrative Anatomy Review provides readers with high-yield information while creating a dynamic working model. The text is based on an approach that begins with a discussion of essential concepts followed by select human cadaver views, concept maps, and synthesis exercises. Students work towards integrating even the most challenging information through retrieval-based learning. Six regions of interest are studied in this edition, including the back, lower limbs, upper limbs, neck, head, and thorax. In collaboration with 4D Anatomy, the reader can gain access to an extensive library of prosected cadaver images to further supplement the text. Developed with the goal of giving readers access to a unique style of learning that maximizes their chances for success, Integrative Anatomy Review is well-suited to courses in undergraduate human anatomy. It is also an excellent supplemental text for health professional students.

This volume provides a comprehensive collection of current methods and protocols to study posttranscriptional base modifications in RNA with special focus on methylation. The protocols in this book discuss state-of-the-art methods for investigating aspects of RNA methylation on different types of RNA. The protocols cover topics such as wet-lab techniques for the detection of methylation, instructions for bioinformatics analyses of transcriptome-scale data, and protocols for the functional examination of RNA modifications and enzymes. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, RNA Methylation: Methods and Protocols is a valuable resource for biochemists and molecular biologists, from various fields, who wish to investigate different types of RNA methylations.

This updated book includes meiosis methods ranging from classical genetic approaches with budding yeast to high resolution microscopy and computational methods for the analysis of recombination and modeling gene expression networks. Cutting-edge procedures for the analysis of double strand breaks at single nucleotide resolution, analysis of translation by ribosome profiling, the use of fluorescent markers to analyze recombination, and strategies for the use of conditional expression to study chromatin protein dynamics are detailed. Advanced cytology methods for live and fixed cell microscopy and image analysis for yeast, drosophila, and mouse are also included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and practical, Meiosis, Second Edition will prove to be invaluable to biologists, geneticists, biochemists, and anyone investigating meiosis, recombination, and cellular differentiation.