Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.

Targets both students or professionals, both novice and experienced, in medical radiotherapy physics. Combines overviews of development, methods and references to facilitate Monte Carlo studies. Focuses on applications in radiotherapy.

"Everything worth winning in life boils down to teamwork and leadership. In my positions as a businessman, athlete, community leader, and University trustee; there are tremendous parallels between all of these endeavors that mirror an extreme team sport such as medical technology. Understanding the game, defining the game, playing your position at your highest performance, and helping others play their best game. Advanced Health Technology represents an incredible opportunity to level up the game of healthcare and highlights the multiple disciplines, or positions to be mastered while laying out winning plays to make that next level happen." Ronnie Lott, Managing Member, Lott Investments; Member, Pro Football Hall of Fame, and Trustee, Santa Clara University "Over the years we've known each other and worked together, Sherri and I have shared a passion for harm reduction. Whether that is due to failure of effective uses and deployment of technology or harm by one of today's biggest threats, drug overdose. We both recognize the need to strategically address the root causes of threats to health and wellbeing. Given that Mobile Medicine and related works are changing the way a whole generation of CTO's and CIO's are thinking about healthcare technology; this new book Advanced Health Technology takes the reader deeper into their leadership journey of transforming medicine with technology by understanding and addressing diverse risks rather than ignoring them." Dean Shold, Co-Founder FentCheck, Former Partner at Accenture, Former CTO Stanford Healthcare and Alameda Health System, former CTO at Medigram and current advisor. Healthcare stakeholders are paralyzed from making progress as risks explode in volume and complexity. This book helps readers understand how to manage and transcend risks to drive the Quadruple Aim of improved patient experiences, better patient and business outcomes, improved clinician experience, and lower healthcare costs. Learn from working successful examples across projects, programs, and careers to get ahead of these multidisciplinary healthcare risks.

As the requirements for low power consumption and very small physical dimensions in portable, wearable and implantable medical devices are calling for integrated circuit design techniques using MOSFETs operating in the subthreshold regime, this book first revisits some well-known circuit techniques that use CMOS devices biased in subthreshold in order to establish nanopower integrated circuit designs. Based on the these findings, this book shows the development of a class-AB current-mode sample-and-hold circuit with an order of magnitude improvement in its figure of merit compared to other state-of-the-art designs. Also, the concepts and design procedures of 1) single-branch filters 2) follower-integrator-based lowpass filters and 3) modular transconductance reduction techniques for very low frequency filters are presented. Finally, to serve the requirement of a very large signal swing in an energy-based action potential detector, a nanopower class-AB current-mode analog multiplier is designed to handle input current amplitudes of more than 10 times the bias current of the multiplier circuit. The invented filter circuits have been fabricated in a standard 0.18 CMOS process in order to verify our circuit concepts and design procedures. Their experimental results are reported.

First Published in 1997. Routledge is an imprint of Taylor & Francis, an informa company.

How Does the Body's Motor Control System Deal with Repetition? While the presence of nonlinear dynamics can be explained and understood, it is difficult to be measured. A study of human movement variability with a focus on nonlinear dynamics, Nonlinear Analysis for Human Movement Variability, examines the characteristics of human movement within this framework, explores human movement in repetition, and explains how and why we analyze human movement data. It takes an in-depth look into the nonlinear dynamics of systems within and around us, investigates the temporal structure of variability, and discusses the properties of chaos and fractals as they relate to human movement. Providing a foundation for the use of nonlinear analysis and the study of movement variability in practice, the book describes the nonlinear dynamical features found in complex biological and physical systems, and introduces key concepts that help determine and identify patterns within the fluctuations of data that are repeated over time. It presents commonly used methods and novel approaches to movement analysis that reveal intriguing properties of the motor control system and introduce new ways of thinking about variability, adaptability, health, and motor learning. In addition, this text: Demonstrates how nonlinear measures can be used in a variety of different tasks and populations Presents a wide variety of nonlinear tools such as the Lyapunov exponent, surrogation, entropy, and fractal analysis Includes examples from research on how nonlinear analysis can be used to understand real-world applications Provides numerous case studies in postural control, gait, motor control, and motor development Nonlinear Analysis for Human Movement Variability advances the field of human movement variability research by dissecting human movement and studying the role of movement variability. The book proposes new ways to use nonlinear analysis and investigate the temporal structure of variability, and enables engineers, movement scientists, clinicians, and those in related disciplines to effectively apply nonlinear analysis in practice.

Broadly tunable lasers continue to have a tremendous impact in many and diverse fields of science and technology. From a renaissance in laser spectroscopy to Bose-Einstein condensation, the one nexus is the tunable laser. Tunable Laser Applications describes the physics and architectures of widely applied tunable laser sources. Fully updated and expanded to address important advances in the science and technology, this Third Edition: Contains new chapters on tunable laser microscopy and tunable laser atomic vapor laser isotope separation Offers extended coverage of optical parametric oscillators and their application to atmospheric sensing, biomedicine, defense counter measures, microscopy, and spectroscopy Discusses exciting new applications in astronomy, defense R&D, medicine, and more Featuring fresh contributions from internationally recognized experts-including 100+ new pages and extensive reference listings-Tunable Laser Applications, Third Edition provides a timely account of the most promising tunable laser applications to date.

This Atlas presents both normal and pathological conditions of the Brain and Spine pictorially. Targeted towards non-radiologists, it is a unique book with well labeled and self-explanatory images. All routine conditions involving neuroradiology have been included. Images from different radiological modalities such as X-ray, Computed Tomography (CT), Magnetic Resonance Imaging (MRI) and Digital Subtraction Angiography (DSA) have also been included. This book aims to serve as a ready reckoner for clinicians, trainees, residents as well as professional radiologists. Key Features Discusses topics related to allied branches of neurology, neuroanesthesia, neurointensive care and neurosurgery Presents both common and uncommon neurological conditions Contains actual real-life scans and images Works as a unique, quick reference guide of neuroradiological images for non-radiologists

This book presents an experimental and computational account of the applications of biopolymers in the field of medicine. Biopolymers are macromolecules produced by living systems, such as proteins, polypeptides, nucleic acids, and polysaccharides. Their advantages over polymers produced using synthetic chemistry include: diversity, abundance, relatively low cost, and sustainability. This book explains techniques for the production of different biodevices, such as scaffolds, hydrogels, functional nanoparticles, microcapsules, and nanocapsules. Furthermore, developments in nanodrug delivery, gene therapy, and tissue engineering are described.

The field of medical imaging seen rapid development over the last two decades and has consequently revolutionized the way in which modern medicine is practiced. Diseases and their symptoms are constantly changing therefore continuous updating is necessary for the data to be relevant. Diseases fall into different categories, even a small difference in symptoms may result in categorising it in a different group altogether. Thus analysing data accurately is of critical importance. This book concentrates on diagnosing diseases like cancer or tumor from different modalities of images. This book is divided into the following domains: Importance of big data in medical imaging, pre-processing, image registration, feature extraction, classification and retrieval. It is further supplemented by the medical analyst for a continuous treatment process. The book provides an automated system that could retrieve images based on user's interest to a point of providing decision support. It will help medical analysts to take informed decisions before planning treatment and surgery. It will also be useful to researchers who are working in problems involved in medical imaging.

Biomaterials, Medical Devices, and Combination Products is a single-volume guide for those responsible for-or concerned with-developing and ensuring patient safety in the use and manufacture of medical devices. The book provides a clear presentation of the global regulatory requirements and challenges in evaluating the biocompatibility and clinical safety of the materials used in producing medical devices as well as the devices themselves. Starting with material characterization and selection, considerations of concerns arising from packaging and contact with production machinery, and extensive coverage of combination products, the book also provides the latest approaches to isolating, quantitating, identifying and assessing the risk arising from chemical entities released from market-ready devices. Also incorporated are new case examples and citations with the means of access to Internet-based regulatory and scientific sites, reflecting the universal adoption of this technology into our world. The book takes into consideration the fact that device markets are global, the continual advancement of technology, and the increasing global harmonization of safety regulations. Each aspect of device safety evaluation is reviewed in terms of the International Organization for Standardization (ISO), US Food and Drug Administration (FDA), European Union (EU), and Japanese Ministry of Health, Labour, and Welfare (MHLW) perspectives.

Cinematic Virtual Reality brings a combination of documentary, narrative and game design principles to the medical profession and, in the healthcare arena, collaboration is a key component for creating intellectually- and emotionally- rich immersive experiences. "The Power of Virtual Reality Cinema for Healthcare Training" gathers more than a dozen experts from both the production and healthcare fields to break down best practices for creating successful cine-VR projects. Designed for multi-disciplinary teams interested in integrating cine-VR production into their healthcare training and educational programs, this book has been written for two audiences: the healthcare professional interested in what production experts consider when approaching a project, and the media expert curious about how this new technology can be used in the medical field. Highlights include: Cutting edge medical education techniques developed by Ohio University's GRID Lab, including: PREality (creating a forced sense of deja-vu to increase acclimation time), a unique approach to eye-tracking to enhance team performance, and the low-CRIS technique (a low-cost rapid implementation strategy to capture patient care for rapid graduate student training). Insightful production techniques that will enhance your cine-VR projects including advanced plating methods to hide lighting set-ups, immersive audio considerations, and new ways to consider 360 storytelling including the Lovrick montage and the Christmas Carol continuum for story development. Detailed explanations of the production considerations and results of specific cine-VR productions (from funding approaches to distribution) including access to more than five hours of cine-VR examples of the actual productions available for download. Details on a wide variety of medical cine-VR projects, including 100 images that illustrate best practices for topics such as recording in active medical facilities, building successful multi-disciplinary teams, working within HIPAA regulations, conceptualizing cine-VR libraries for graduate education, and implementing innovative distribution models.

How do development and use of new technology relate? How can users contribute to innovation? This volume is the first to study these questions by following particular technologies over several product launches in detail. It examines the emergence of inventive ideas about future technology and uses, how these are developed into products and embedded in health care practices, and how the form and impact of these technologies then evolves through several rounds of design and deployment across different types of organizations. Examining these processes through three case studies of health care innovations, these studies reveal a blind spot in extant research on development-use relations. The majority of studies have examined shorter 'episodes': moments within particular design projects, implementation processes, usability evaluations, and human-machine interactions. Studies with longer time-frames have resorted to a relatively coarse 'grain-size' of analysis and hence lost sight of how the interchange is actually done. As a result there are no social science, information systems, or management texts which comprehensively or adequately address: * how different moments, sites and modes of shaping new technology determine the evolution of new technology; * the detailed mechanisms of learning, interaction, and domination between different actors and technology during these drawn out processes; and * the relationship of technology projects and the professional practices and social imaginations that are associated in technology development, evaluation, and usage. The "biographies of technologies and practices" approach to new technology advanced in this volume offers us urgent new insight to core empirical and theoretical questions about how and where development projects gain their representations of future use and users, how usage is actually designed, how users' requests and modifications affect designs, and what kind of learning takes place between developers and users in different phases of innovation-all crucial to our understanding and ability to advance new health technology, and innovation more generally.

The book presents the field of neuromorphic engineering from the perspectives of the scientist, the algorithm designer, and the computer architect. It covers the fundamentals of neuronal modeling, neuromorphic circuits, neuronal architectures, the neural engineering framework, and neuromorphic machine learning. It zooms in and out of the different disciplines, allowing readers with diverse backgrounds to understand and appreciate the field. The book walks the thin line of being descriptive enough to give the reader a clear understanding while not being too technical and tedious. It was designed for graduate students in the fields of computer science, electrical engineering, neuroscience, and computational biology.

This book brings together a collection of empirical case studies featuring a wide spectrum of medical innovation. While there is no unique pathway to successful medical innovation, recurring and distinctive features can be observed across different areas of clinical practice. This book examines why medical practice develops so unevenly across and within areas of disease, and how this relates to the underlying conditions of innovation across areas of practice. The contributions contained in this volume adopt a dynamic perspective on medical innovation based on the notion that scientific understanding, technology and clinical practice co-evolve along the co-ordinated search for solutions to medical problems. The chapters follow an historical approach to emphasise that the advancement of medical know-how is a contested, nuanced process, and that it involves a variety of knowledge bases whose evolutionary paths are rooted in the contexts in which they emerge. This book will be of interest to researchers and practitioners concerned with medical innovation, management studies and the economics of innovation. Chapter 5 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138860346_oachapter5.pdf

Medical Instruments and Devices: Principles and Practices originates from the medical instruments and devices section of The Biomedical Engineering Handbook, Fourth Edition. Top experts in the field provide material that spans this wide field. The text examines how biopotential amplifiers help regulate the quality and content of measured signals. It includes instruments and devices that span a range of physiological systems and the physiological scale: molecular, cellular, organ, and system. The book chronicles the evolution of pacemakers and their system operation and discusses oscillometry, cardiac output measurement, and the direct and indirect methods of measuring cardiac output. The authors also expound on the mechanics and safety of defibrillators and cover implantable stimulators, respiration, and the structure and function of mechanical ventilators. In addition, this text covers in depth: Anesthesia Delivery Electrosurgical Units and Devices Biomedical Lasers Measuring Cellular Traction Forces Blood Glucose Monitoring Atomic Force Microscopy Parenteral Infusion Devices Clinical Laboratory: Separation and Spectral Methods Clinical Laboratory: Nonspectral Methods and Automation Noninvasive Optical Monitoring An offshoot from the definitive "bible" of biomedical engineering, Medical Instruments and Devices: Principles and Practices offers you state-of-the-art information on biomedical instruments and devices. This text serves practicing professionals working in the areas of medical devices and instrumentation as well as graduate students studying bioengineering, instrumentation, and medical devices, and it provides readers with a practical foundation and a wealth of resources from well-known experts in the field.

Covers micro- and Nano- technologies approaches with current trends with safety and efficacy in product development. Presents overview of recent progress of stability testing, reverse engineering, validation and regulatory perspectives as per regulatory requirements. Provides comprehensive overview of latest research related to the micro and nanotechnological including designing, optimization, validation, scale of micro and nanotechnologies. This book is edited by the two-well known researchers by contribution of the vivid chapters from renowned scientists across the globe in field of pharmaceutical sciences.

Contains over 3300 entries with accompanying diagrams, images, formulas, further reading, and examples Covers both the classical and newest elements in medical imaging, radiotherapy, and radiation protection Discusses material at a level accessible to graduate and postgraduate students in medical physics and related disciplines as well as medical specialists and researchers.

Low-Level Laser Therapy (LLLT) also known as photobiomodulation is almost 50 years old, and recently has been getting increasing acceptance from the scientific, medical, and veterinary communities. Discoveries are constantly being made about the cellular and molecular mechanisms of action, the range of diseases that can be treated is also rising, and home use LED devices are becoming common. This book compiles cutting-edge contributions from the world's leading experts in Photobiomodulation and LLLT. Chapters cover general concepts, mechanisms of action, in vitro studies, pre-clinical animal studies, veterinary applications and a wide range of clinical topics. Edited by Michael Hamblin from Massachusetts General Hospital and Harvard Medical School, aided by two prominent researchers (Marcelo Sousa and Tanupriya Agrawal), this book will appeal to anyone involved in the basic science, translational aspects and clinical applications of LLLT.

This interdisciplinary study participates in the ongoing critical conversation about postwar American poetry and visual culture, while advancing that field into the arena of the museum. Turning to contemporary poems about the visual arts that foreground and interrogate a museum setting, the book demonstrates the particular importance of the museum as a cultural site that is both inspiration and provocation for poets. The study uniquely bridges the "dual canon" in contemporary poetry (and calls the lyric/avant-garde distinction into question) by analyzing museum-sponsored anthologies as well as poems by John Ashbery, Richard Howard, Kenneth Koch, Kathleen Fraser, Cole Swensen, Anne Carson, and others. Through these case studies of poets with diverse affiliations, the author shows that the boom in ekphrasis in the past 20 years is not only an aesthetic but a critical phenomenon, a way that poets have come to terms with the critical dilemmas of our moment. Highlighting the importance of poets' "peripheral vision"-awareness of the institutional conditions that frame encounters with art-the author contend that a museum visit becomes a forum for questioning oppositions that have preoccupied literary criticism for the past 50 years: homage and innovation, modernism and postmodernism, subjectivity and collectivity. The study shows that ekphrasis becomes a strategy for negotiating these impasses-a mode of political inquiry, a meditation on canonization, a venue for comic appraisal of institutionalization, and a means of "site-specific" feminist revision-in a vital synthesis of critique, perspicacity, and pleasure.

Nanoparticles have a physical dimension comparable to the size of molecular structures on the cell surface. Therefore, nanoparticles, compared to larger (e.g., micrometer) particles, are considered to behave differently when they interact with cells. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery provides a better understanding of how inhaled nanoparticles behave in the human lungs and body. Featuring contributions from renowned subject-matter experts, this authoritative text describes the sequence of events that nanoparticles encounter in the lungs when moving from the air into the bloodstream. This includes deposition, interactions with the alveolar surface and epithelium, translocation across the air-blood tissue barrier, and accumulation in the body. In addition, the book addresses practical considerations for drug delivery to the respiratory tract, drug and gene delivery in the lungs, and bio-nanocapsules. It considers the physicochemical, colloidal, and transport properties of nanoparticles, and presents cutting-edge research on special issues such as dosimetry for in vitro nanotoxicology, nanoparticle deposition in the developing lungs, and the potential for nose-to-brain delivery of drugs. Nanoparticles in the Lung: Environmental Exposure and Drug Delivery offers the most updated and comprehensive knowledge of the risks and benefits associated with nanoparticle inhalation-to protect humans from any harmful effects and to explore the utility of nanoparticles as drug delivery carriers.

Biomedical patents have been the subject of heated debate. Regulatory agencies such as the European Patent Office make small decisions with big implications, which escape scrutiny and revision, when they decide who has access to expensive diagnostic tests, whether human embryonic stem cells can be traded in markets, and under what circumstances human health is more important than animal welfare. Moreover, the administration of the Trade Related Aspects of Intellectual Property Rights by the World Trade Organization has raised considerable disquiet as it has arguably created grave health inequities. Those doubting the merits of the one size fits all approach ask whether priority should be given to serving the present needs of populations in dire need of medication or to promoting global innovation. The book looks in detail into the legal issues and ethical debates to ask the following three main questions: First, what are the ideas, goals, and broader ethical visions that underpin questions of governance and the legal reasoning employed by administrative agencies? Second, how can we democratize the decision making process of technocratic institutions such as the European Patent Office? Finally, how can we make the global intellectual property system more equitable? In answering these questions the book seeks to contribute to our understanding of the role and function of regulatory agencies in the regulation of the bioeconomy, explains the process of interpretation of legal norms, and proposes ways to rethink the reform of the patent system through the lens of legitimacy.

The book offers unique insight into the modern world of wireless communication that included 5G generation, implementation in Internet of Things (IoT), and emerging biomedical applications. To meet different design requirements, gaining perspective on systems is important. Written by international experts in industry and academia, the intended audience is practicing engineers with some electronics background. It presents the latest research and practices in wireless communication, as industry prepares for the next evolution towards a trillion interconnected devices. The text further explains how modern RF wireless systems may handle such a large number of wireless devices. Covers modern wireless technologies (5G, IoT), and emerging biomedical applications Discusses novel RF systems, CMOS low power circuit implementation, antennae arrays, circuits for medical imaging, and many other emerging technologies in wireless co-space. Written by a mixture of top industrial experts and key academic professors.

A significant portion of biomedical applications necessitates the establishment of an interface between the cells of the patient and the components of the device. In many cases, such as in implants and engineered tissues, the interaction of the cells with the biomaterial is one of the main determinants of the success of the system. Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies explores this interaction and its control at length scales ranging from the nano to the macro. Featuring contributions from leading molecular biologists, chemists, and material scientists, this authoritative reference: Presents practical examples of cell and material interface-based applications Reflects the interdisciplinary nature of bioengineering, covering topics such as biosensing, immunology, and controlled delivery Explains the role of the cell and material interface in the context of cardiac and skin tissue engineering, nanoparticles, natural polymers, and more Cell and Material Interface: Advances in Tissue Engineering, Biosensor, Implant, and Imaging Technologies addresses concepts essential to biomaterial production methods and cell and material interactions. The book provides a solid starting point for elucidating and exploiting the different aspects of cellular interactions with materials for biomedical engineering.

This book brings together a collection of empirical case studies featuring a wide spectrum of medical innovation. While there is no unique pathway to successful medical innovation, recurring and distinctive features can be observed across different areas of clinical practice. This book examines why medical practice develops so unevenly across and within areas of disease, and how this relates to the underlying conditions of innovation across areas of practice. The contributions contained in this volume adopt a dynamic perspective on medical innovation based on the notion that scientific understanding, technology and clinical practice co-evolve along the co-ordinated search for solutions to medical problems. The chapters follow an historical approach to emphasise that the advancement of medical know-how is a contested, nuanced process, and that it involves a variety of knowledge bases whose evolutionary paths are rooted in the contexts in which they emerge. This book will be of interest to researchers and practitioners concerned with medical innovation, management studies and the economics of innovation. Chapter 5 of this book is freely available as a downloadable Open Access PDF under a Creative Commons Attribution-Non Commercial-No Derivatives 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781138860346_oachapter5.pdf