Neuroprosthetics is a fast-growing area that brings together the fields of biomedical engineering and neuroscience as a means to interface the neural system directly to prostheses. Advancing research and applications in this field can assist in successfully restoring motor, sensory, and cognitive functions. Emerging Theory and Practice in Neuroprosthetics brings together the most up-to-date research surrounding neuroprosthetics advances and applications. Presenting several new results, concepts, and further developments in the area of neuroprosthetics, this book is an essential publication for researchers, upper-level students, engineers, and medical practitioners.

The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling.

This book provides a snapshot of the state of current research at the interface between machine learning and healthcare with special emphasis on machine learning projects that are (or are close to) achieving improvement in patient outcomes. The book provides overviews on a range of technologies including detecting artefactual events in vital signs monitoring data; patient physiological monitoring; tracking infectious disease; predicting antibiotic resistance from genomic data; and managing chronic disease. With contributions from an international panel of leading researchers, this book will find a place on the bookshelves of academic and industrial researchers and advanced students working in healthcare technologies, biomedical engineering, and machine learning.

Chitosan in Biomedical Applications provides a thorough insight into the complete chitosan chemistry, collection, chemical modifications, characterization and applications of chitosan in biomedical applications and healthcare fields. Chitosan, a biopolymer of natural origin, has been explored for its variety of applications in biomedical research, medical diagnostic aids and material science. It is the second most abundant natural biopolymer after cellulose, and considered as an excellent excipient because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of chitosan in biomedical applications. The book explores key topics, such as molecular weight, degree of deacetylation, and molecular geometry, along with an emphasis on recent advances in the field written by academic, industry, and clinical researchers. Chitosan in Biomedical Applications will be of interest to those in biomedical fields including the biomaterials and tissue engineering community investigating and developing biomaterials for biomedical applications, particularly graduate students, young faculty and others exploring chitosan-based materials.

Total hip arthroplasty, the most commonly performed orthopedic procedure, is used to replace or reconstruct the hip with an artificial joint. "Perspectives in Total Hip Arthroplasty" outlines developments in technologies and biomaterials used for this procedure, with a focus on the tribological interactions of the materials used.

Part one outlines the history of total hip arthroplasty and goes on to explore advances in techniques and biomaterials. Part two focuses on the tribology of materials used to perform this procedure, explaining the impact of wear on the load-bearing surface, a major cause of failure in hip prostheses. Chapters review a range of materials, including modern biomaterials, hybrid materials, metal, ceramic, and polyethylene. The book also discusses the tribological interactions of these materials when used in total hip arthroplasty.

"Perspectives in Total Hip Arthroplasty "is a key resource for clinicians, researchers, and academics interested in the tribology of total hip arthroplasty, as well as materials researchers, engineers, and academics concerned with the tribology of biomaterials.
Covers techniques from innovative surgeons and designs from multinational manufacturers, as well as information on improvements in technologies and biomaterialsDiscusses the tribology of all the major materials used in total hip arthroplasty

This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. "Principles of Biomedical Informatics, "2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: tree structured data, interval trees, and time-oriented medical data and their use On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing an introduction to Markov processes, and an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies.

It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields.

As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation.

The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling.
* Develops principles and methods for representing biomedical data, using information in context and in decision making, and accessing information to assist the medical community in using data to its full potential
* Provides a series of principles for expressing biomedical data and ideas in a computable form to integrate biological, clinical, and public health applications
* Includes a discussion of user interfaces, interactive graphics, and knowledge resources and reference material on programming languages to provide medical informatics programmers with the technical tools to develop systems"

Technological tools and computational techniques have enhanced the healthcare industry. These advancements have led to significant progress and novel opportunities for biomedical engineering. Nature-Inspired Intelligent Techniques for Solving Biomedical Engineering Problems is a pivotal reference source for emerging scholarly research on trends and techniques in the utilization of nature-inspired approaches in biomedical engineering. Featuring extensive coverage on relevant areas such as artificial intelligence, clinical decision support systems, and swarm intelligence, this publication is an ideal resource for medical practitioners, professionals, students, engineers, and researchers interested in the latest developments in biomedical technologies.

Nanoparticle therapeutics: Production Technologies, Types of Nanoparticles, and Regulatory Aspects employs unique principles for applications in cell-based therapeutics, diagnostics and mechanistics for the study of organ physiology, disease etiology and drug screening of advanced nanoparticles and nanomaterials. The book focuses on the extrapolation of bioengineering tools in the domain of nanotechnology and nanoparticles therapeutics, fabrication, characterization and drug delivery aspects. It acquaints scientists and researchers on the experiential and experimental aspects of nanoparticles and nanotechnology to equip their rational application in various fields, especially in differential diagnoses and in the treatment of diverse diseased states. This complete resource provides a holistic understanding of the principle behind formation, characterization, applications, regulations and toxicity of nanoparticles employing myriad principles of nanotechnology. Investigators, pharmaceutical researchers, and advanced students working on technology advancement in the areas of designing targeted therapies, nanoscale imaging systems and diagnostic modalities in human diseases where nanoparticles can be used as a critical tool for technology advancement in drug delivery systems will find this book useful.

Comprises four parts, the first of which provides an overview of the topics that are developed from fundamental principles to more advanced levels in the other parts. Presents in the second part an in-depth introduction to the relevant background in molecular and cellular biology and in physical chemistry, which should be particularly useful for students without a formal background in these subjects. Provides in the third part a detailed treatment of microscopy techniques and optics, again starting from basic principles. Introduces in the fourth part modern statistical approaches to the determination of parameters of interest from microscopy data, in particular data generated by single molecule microscopy experiments. Uses two topics related to protein trafficking (transferrin trafficking and FcRn-mediated antibody trafficking) throughout the text to motivate and illustrate microscopy techniques

This special volume of Progress in Molecular Biology and Translational Science focuses on oligomerization in health and disease.

Key features:

* Contributions from leading authorities * Informs and updates on all the latest developments in the field

Technology continues to play a major role in all aspects of society, particularly healthcare. Advancements such as biomedical image processing, technology in rehabilitation, and biomedical robotics for healthcare have aided in significant strides in the biomedical engineering research field.Technological Advancements in Biomedicine for Healthcare Applications presents an overview of biomedical technologies and its relationship with healthcare applications. This reference source is essential for researchers and practitioners aiming to learn more about biomedical engineering and its related fields.

New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants).

This book brings together an international team of experts from the fields of materials science, nanotechnology and dentistry, to explain these new materials and their applications for the restoration, fixation, replacement, or regeneration of hard and soft tissues in and about the oral cavity and craniofacial region.

The main topics covered include applications in dental specialties (Orthodontics, Endodontics, Pediatric dentistry, Periodontics, Prosthodontics and Implant dentistry), salivary diagnostics using bioMEMS/NEMS systems, nanochips for oral cancer diagnosis, biomimetic nanomaterials, and nanotechnology for tooth repair and regeneration.

The editors' previous book, "Emerging Nanotechnologies in Dentistry "focused on the fabrication/manufacturing processes of materials and dentistry applications. This second book complements the first covers with coverage of the range of nanomaterials available today in clinical dentistry, explaining the innovative techniques and applications in all of the main clinical dental specialties.

Nanobiomaterial engineers, biomedical researchers, biomedical engineers and dental/oral pre-clinical and clinical researchers will find the comprehensive coverage essential for working with nanotechnologies and materials in both clinical and research settings.

Book prepared by an interdisciplinary and international group of scientists and practitioners in the fields of

nanomaterials, dental implants, medical devices and clinical practice.

Comprehensive professional reference for the subject covering materials fabrication and use of materials for all major

diagnostic and therapeutic dental applications - repair, restoration, regeneration, implants and prevention.

Complements the editors' previous book on nanotechnology applications for dentistry."

Written by leading optical phase microscopy experts, this book is a comprehensive reference to phase microscopy and nanoscopy techniques for biomedical applications, including differential interference contrast (DIC) microscopy, phase contrast microscopy, digital holographic microscopy, optical coherence tomography, tomographic phase microscopy, spectral-domain phase detection, and nanoparticle usage for phase nanoscopy

The Editors show biomedical and optical engineers how to use phase microscopy for visualizing unstained specimens, and support the theoretical coverage with applied content and examples on designing systems and interpreting results in bio- and nanoscience applications.
Provides a comprehensive overview of the principles and techniques of optical phase microscopy and nanoscopy with biomedical applications.

Tips/advice on building systems and working with advanced imaging biomedical techniques, including interpretation of phase images, and techniques for quantitative analysis based on phase microscopy.

Interdisciplinary approach that combines optical engineering, nanotechnology, biology and medical aspects of this topic. Each chapterincludes practical implementations and worked examples. "

Updated with new and expanded chapters, Endocrine Disruption and Human Health, Second Edition provides an introduction to what endocrine disruptors are, the issues surrounding them, the source of these chemicals in the ecosystem and the mechanisms of action and assay systems. Contributions by specialists are included to discuss the varying effects of endocrine disruption on human health, and procedures for risk assessment of endocrine disruptors, and current approaches to their regulation are also covered. With new material on topics such as low-term, low dose mixtures, windows of susceptibility, epigenetics, EDCs effect on the gut microbiome, EDCs in from polluted air and oral exposures, green chemistry, and nanotechnology, the new edition of Endocrine Disruption and Human Health is a valuable and informative text for academic and clinical researchers and other health professionals approaching endocrine disruption and its effects on human health for the first time, graduate students, and advanced undergraduate students.

This book introduces various 3D printing systems, biomaterials, and cells for organ printing. In view of the latest applications of several 3D printing systems, their advantages and disadvantages are also discussed. A basic understanding of the entire spectrum of organ printing provides pragmatic insight into the mechanisms, methods, and applications of this discipline. Organ printing is being applied in the tissue engineering field with the purpose of developing tissue/organ constructs for the regeneration of both hard (bone, cartilage, osteochondral) and soft tissues (heart). There are other potential application areas including tissue/organ models, disease/cancer models, and models for physiology and pathology, where in vitro 3D multicellular structures developed by organ printing are valuable.

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how induced pluripotent stem cells (iPSCs) are being used to advance tissue engineering. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This book will address the advances in research of how iPSCs are being used for the generation of different tissues and organs such as the lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and tissue engineering and is contributed by world-renowned authors in the field.

There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients.
After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration.
With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice.
Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patientsReviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgeryDiscusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty

Breaches and identity theft involving medical data are on the rise. Data security has become especially critical to the healthcare industry as patient privacy hinges on legal compliance and secure adoption of electronic health records. As cyber criminals see medical data as an easy way to illegally obtain medical goods and services or sell sensitive information, major security flaws can pose serious threats to the health and safety of patients. The Handbook of Research on Medical Data Security for Bioengineers seeks to provide a cross-disciplinary forum on research in privacy preserving healthcare systems and engineering applications in medical data security. The goal of the book is to instigate discussion on these critical issues since the success of electronic healthcare applications depends directly on patient security and privacy for ethical and legal reasons. While highlighting topics including data privacy, encryption strategies, and smart health, this book is ideally designed for IT experts, computer engineers, biomedical engineer practitioners, professionals, researchers, and post-doctoral and graduate students.

Methods for detecting protein-protein interactions (PPIs) have given researchers a global picture of protein interactions on a genomic scale. ""Biological Data Mining in Protein Interaction Networks"" explains bioinformatic methods for predicting PPIs, as well as data mining methods to mine or analyze various protein interaction networks. A defining body of research within the field, this book discovers underlying interaction mechanisms by studying intra-molecular features that form the common denominator of various PPIs.

From exoskeletons to neural implants, biomedical devices are no less than life-changing. Compact and constant power sources are necessary to keep these devices running efficiently. Edwar Romero's "Powering Biomedical Devices" reviews the background, current technologies, and possible future developments of these power sources, examining not only the types of biomedical power sources available (macro, mini, MEMS, and nano), but also what they power (such as prostheses, insulin pumps, and muscular and neural stimulators), and how they work (covering batteries, biofluids, kinetic and thermal energy, and telemetry).

The book also looks at challenges such as energy generation efficiency, energy density, rectification, and energy storage and management. A final section on future trends rounds out the book. By briefly examining these key aspects, this book gives its readers a valuable overview of biomedical devices' power sources.
A compact introduction to the vital topic of biomedical devices' power sourcesReviews the background, current technologies, and possible future developments of biomedical power sourcesShort-format text allows for material that is clear, concise, and to-the-pointExtensive references provided for further reading

This edited book explores the use of mobile technologies such as phones, drones, robots, apps, and wearable monitoring devices for improving access to healthcare for socially disadvantaged populations in remote, rural or developing regions. This book brings together examples of large scale, international projects from developing regions of China and Belt and Road countries from researchers in Australia, Bangladesh, Denmark, Norway, Japan, Spain, Thailand and China. The chapters discuss the challenges presented to those seeking to deploy emerging mobile technologies (e.g., smartphones, IoT, drones, robots etc.) for healthcare (mHealth) in developing countries and discuss the solutions undertaken in these case study projects. This book brings together joint work in mHealth projects across multiple disciplines (software, healthcare, mobile communications, entrepreneurship and business and social development). Bringing together research from different institutions and disciplines, the editors illustrate the technical and entrepreneurial aspects of using mobile technologies for healthcare development in remote regions. Chapters are grouped into five key themes: the global challenge, portable health clinics, sustainable and resilient mHealth services, mHealth for the elderly, and mHealth for chronic illnesses. The book will be of particular interest to engineers, entrepreneurs, NGOs and researchers working in healthcare in sustainable development settings.

Over the past few decades, there has been unprecedented progress in the design of versatile biopolymer-based nanoplatforms for pharmaceutical and biomedical applications, particularly due to their attractive traits, including excellent biocompatibility, outstanding biodegradability, low immunogenicity, and facile chemical modifiability. Biopolymer-Based Nanomaterials in Drug Delivery and Biomedical Applications serves as a clear and detailed body of information on the synthesis and characterization of biopolymer-based materials in nanomedicine. This book describes various nanomaterials consisting of biopolymers including polysaccharides (i.e., derived from plants, animals, bacteria, algae, and fungi) and polypeptides in terms of their structures, synthetic protocols, and characterization and uses as therapeutic drugs and gene delivery carriers and in other biomedical fields. The chapters of this book, which are contributed by internationally renowned scholars working in the arena of biopolymer-based nanomaterials, would offer a wide vision on the potential future applications of these nanomaterials in the delivery and targeting of bioactive molecules of pharmaceutical interests and in tissue engineering, biosensing, bioimaging, and diagnostic purposes. The state-of-the-art information presented in the book would also encourage young investigators and researchers to further bring cutting-edge developments in the field of nanomedicine in the near future.

IoT-enabled healthcare technologies can be used for remote health monitoring, rehabilitation assessment and assisted ambient living. Healthcare analytics can be applied to the data gathered from these different areas to improve healthcare outcomes by providing clinicians with real-world, real-time data so they can more easily support and advise their patients. The book explores the application of AI systems to analyse patient data and guide interventions. IoT-based monitoring systems and their security challenges are also discussed. The book is designed to be a reference for healthcare informatics researchers, developers, practitioners, and people who are interested in the personalised healthcare sector. The book will be a valuable reference tool for those who identify and develop methodologies, frameworks, tools, and applications for working with medical big data and researchers in computer engineering, healthcare electronics, device design and related fields.