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Books > Medicine > Nursing & ancillary services > Biomedical engineering > General

The Artificial Knee - An Ongoing Evolution (Hardcover, 1st ed. 2020): Peter S. Walker The Artificial Knee - An Ongoing Evolution (Hardcover, 1st ed. 2020)
Peter S. Walker
R3,251 Discovery Miles 32 510 Ships in 7 - 11 working days

Spanning both the history and future of knee replacement, this unique book recounts how artificial knees have reached the stage they are today, and whether their performance can be further improved. The author, who has been designing artificial knees for 50 years, starts the story in the late 1960's with the early pioneers; during the 1970's, the principles for successful artificial knees were established. While many different types were designed, a small number have become by far the most widely utilized. Yet other types of designs, so far little used, along with new materials and the application of computer-assisted surgery, could result in significant advancements in the treatment of knee arthritis. Each chapter provides a detailed description of the origins of the ideas and principles and their rationale, followed by the latest information and evidence. The book begins with an overview of the history and background of the artificial knee, in terms of design and implementation and the thought leaders involved. Fixation, biomechanics, and the types of designs are discussed in detail, both what has worked and what has not, and why. Instrumentation, testing and tribology, and functional evaluation methods are also covered. The book concludes with a look toward the future possibilities for the field of artificial knees. An illustrated glossary of terms, is included for quick reference. The Artificial Knee: An Ongoing Evolution will appeal to orthopedic surgeons and researchers, medical academics and orthopedic companies, and to those with a general interest in artificial knees.

Handbook of Thermal Science and Engineering (Hardcover, 1st ed. 2018): Francis A. Kulacki Handbook of Thermal Science and Engineering (Hardcover, 1st ed. 2018)
Francis A. Kulacki; Volume editing by Sumanta Acharya, Yaroslav Chudnovsky, Renato Machado Cotta, Ram Devireddy, …
R27,571 R23,559 Discovery Miles 235 590 Save R4,012 (15%) Ships in 10 - 15 working days

This Handbook provides researchers, faculty, design engineers in industrial R&D, and practicing engineers in the field concise treatments of advanced and more-recently established topics in thermal science and engineering, with an important emphasis on micro- and nanosystems, not covered in earlier references on applied thermal science, heat transfer or relevant aspects of mechanical/chemical engineering. Major sections address new developments in heat transfer, transport phenomena, single- and multiphase flows with energy transfer, thermal-bioengineering, thermal radiation, combined mode heat transfer, coupled heat and mass transfer, and energy systems. Energy transport at the macro-scale and micro/nano-scales is also included. The internationally recognized team of authors adopt a consistent and systematic approach and writing style, including ample cross reference among topics, offering readers a user-friendly knowledgebase greater than the sum of its parts, perfect for frequent consultation. The Handbook of Thermal Science and Engineering is ideal for academic and professional readers in the traditional and emerging areas of mechanical engineering, chemical engineering, aerospace engineering, bioengineering, electronics fabrication, energy, and manufacturing concerned with the influence thermal phenomena.

Concepts in Bioscience Engineering (Hardcover, 1st ed. 2019): Richard Dods Concepts in Bioscience Engineering (Hardcover, 1st ed. 2019)
Richard Dods
R1,995 Discovery Miles 19 950 Ships in 10 - 15 working days

This textbook teaches bioengineers critical concepts about protein three dimensional structures, how proteins fold, and how the folding affects the functioning of the protein. Protein folding has profound effects on the discovery of biopharmaceutical drugs (especially the transport of immunological compounds to their site of action) as well as on tissue engineering. Dr. Dods covers topics in easily understood terms through the use of glossaries heading each chapter and footnotes and summaries at the end of each chapter. The chapters cover disordered proteins and large sequences of disorder that exists within proteins, secondary structure ( -helix and -pleated structure), tertiary and quaternary structure, post-translational changes, proteopathies, bioengineering approaches used to study protein folding, and computer software for protein folding. For each of these topics the elements of biomolecular imaging, cellular and tissue engineering, and health care systems engineering are built. Molecular engineering concepts such as site-directed mutagenesis are addressed. For reinforcement of the concepts presented in this text, activities and problems (Queries) are included in the chapter.

Dendrimers in Biomedical Applications (Hardcover): Barbara Klajnert, Ling Peng, Valentin Cena Dendrimers in Biomedical Applications (Hardcover)
Barbara Klajnert, Ling Peng, Valentin Cena
R3,927 Discovery Miles 39 270 Ships in 7 - 11 working days

1. COST book focussing on improving existing therapies and finding new drugs based on dendrimers; 2. Important in drug delivery methods and therefore for drug discovery; 3. Biochemistry, pharmaceutical science, biomaterials science, drug discovery, therapeutic delivery; 4. Possible cross-promotion with drug discovery series; 5. Dendrimers are synthetic branched molecules allowing them to be easily targeted for specific receptors.

Introduction To Bioceramics, An (2nd Edition) (Hardcover, 2nd edition): Larry L. Hench Introduction To Bioceramics, An (2nd Edition) (Hardcover, 2nd edition)
Larry L. Hench
R2,344 R1,879 Discovery Miles 18 790 Save R465 (20%) Ships in 10 - 15 working days

This is the second edition of the classic book An Introduction to Bioceramics which provides a comprehensive overview of all types of ceramic and glass materials that are used in medicine and dentistry. The enormous growth of the field of bioceramics is due to the recognition by the medical and dental community of the importance of bioactive materials to stimulate repair and regeneration of tissues. This edition includes 21 new chapters that document the science and especially the clinical applications of the new generation of bioceramics in the field of tissue regeneration and repair. Important socioeconomic factors influencing the economics and availability of new medical treatments are covered with updates on regulatory procedures for new biomaterials, methods for technology transfer and ethical issues.The book contains 42 chapters that offer the only comprehensive treatment of the science, technology and clinical applications of all types of bioceramic materials used in medicine and dentistry. Each chapter is written by leaders in their specialized fields and is a thorough review of the subject matter, unlike many conference proceedings. All chapters have been edited to reflect the same writing style, making the book an easy read. The completeness of treatment of all types of bioceramics and their clinical applications makes the book unique in the field and invaluable to all readers.

Biomimetic Robotic Artificial Muscles (Hardcover): Kwang-Jin Kim, Hyouk Ryeol Choi, Xiaobo Tan, David Pugal Biomimetic Robotic Artificial Muscles (Hardcover)
Kwang-Jin Kim, Hyouk Ryeol Choi, Xiaobo Tan, David Pugal
R2,255 Discovery Miles 22 550 Ships in 10 - 15 working days

Biomimetic Robotic Artificial Muscles presents a comprehensive up- to-date overview of several types of electroactive materials with a view of using them as biomimetic artificial muscles. The purpose of the book is to provide a focused, in-depth, yet self-contained treatment of recent advances made in several promising EAP materials. In particular, ionic polymer-metal composites, conjugated polymers, and dielectric elastomers are considered. Manufacturing, physical characterization, modeling, and control of the materials are presented. Namely, the book adopts a systems perspective to integrate recent developments in material processing, actuator design, control-oriented modeling, and device and robotic applications. While the main focus is on the new developments in these subjects, an effort has been made throughout the book to provide the reader with general, basic information about the materials before going into more advanced topics. As a result, the book is very much self-contained and expected to be accessible for a reader who does not have background in EAPs. Based on the good fundamental knowledge and the versatility of the materials, several promising biomimetic and robotic applications such robotic fish propelled by an IPMC tail, an IPMC energy harvester, an IPMC-based valveless pump, a conjugated polymer petal-driven micropump, and a synthetic elastomer actuator-enabled robotic finger are demonstrated.

Functional Polymers for Nanomedicine (Hardcover): Youqing Shen Functional Polymers for Nanomedicine (Hardcover)
Youqing Shen
R4,485 Discovery Miles 44 850 Ships in 7 - 11 working days

Interest in the application of nanotechnology to medicine has surged in recent years and could transform the way we diagnose, treat and prevent diseases such as cancer. However, the clinical success of nanomedicine is limited because of problems with toxicity and therapeutic efficacy. To overcome this it is essential to produce new nanosystems with specific functions, which can be achieved by designing new polymers with particular properties that can be used for nanomedicine. Functional Polymers for Nanomedicine provides a complete overview of the different strategies for designing polymers for nanomedicine applications. The first part of the book looks at the current problems and direction in nanomedicine including a review of current design and targeting of nanocarriers. The second part explores the design of polymers with different functions including hyperbranched polymers, polymersomes, polysaccharides, polymeric micelles and zwitterionic polymers and their applications in gene therapy and drug delivery. This timely book is edited by a leading scientist in nanomedicine and provides a suitable introduction and reference source for advanced undergraduates, postgraduates and academic and industrial researchers in polymer science, nanotechnology and pharmacy interested in materials for medical applications.

Computer-Aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer (Paperback): Shantanu Banik,... Computer-Aided Detection of Architectural Distortion in Prior Mammograms of Interval Cancer (Paperback)
Shantanu Banik, Rangaraj Rangayyan, J.E. Leo Desautels
R1,017 Discovery Miles 10 170 Ships in 7 - 11 working days

Architectural distortion is an important and early sign of breast cancer, but because of its subtlety, it is a common cause of false-negative findings on screening mammograms. Screening mammograms obtained prior to the detection of cancer could contain subtle signs of early stages of breast cancer, in particular, architectural distortion. This book presents image processing and pattern recognition techniques to detect architectural distortion in prior mammograms of interval-cancer cases. The methods are based upon Gabor filters, phase portrait analysis, procedures for the analysis of the angular spread of power, fractal analysis, Laws' texture energy measures derived from geometrically transformed regions of interest (ROIs), and Haralick's texture features. With Gabor filters and phase-portrait analysis, 4,224 ROIs were automatically obtained from 106 prior mammograms of 56 interval-cancer cases, including 301 true-positive ROIs related to architectural distortion, and from 52 mammograms of 13 normal cases. For each ROI, the fractal dimension, the entropy of the angular spread of power, 10 Laws' texture energy measures, and Haralick's 14 texture features were computed. The areas under the receiver operating characteristic (ROC) curves obtained using the features selected by stepwise logistic regression and the leave-one-image-out method are 0.77 with the Bayesian classifier, 0.76 with Fisher linear discriminant analysis, and 0.79 with a neural network classifier. Free-response ROC analysis indicated sensitivities of 0.80 and 0.90 at 5.7 and 8.8 false positives (FPs) per image, respectively, with the Bayesian classifier and the leave-one-image-out method. The present study has demonstrated the ability to detect early signs of breast cancer 15 months ahead of the time of clinical diagnosis, on the average, for interval-cancer cases, with a sensitivity of 0.8 at 5.7 FP/image. The presented computer-aided detection techniques, dedicated to accurate detection and localization of architectural distortion, could lead to efficient detection of early and subtle signs of breast cancer at pre-mass-formation stages.

Content-based Retrieval of Medical Images - Landmarking, Indexing, and Relevance Feedback (Paperback): Mazzoncini de... Content-based Retrieval of Medical Images - Landmarking, Indexing, and Relevance Feedback (Paperback)
Mazzoncini de Azevedo-Marques, Rangaraj Rangayyan
R899 Discovery Miles 8 990 Ships in 7 - 11 working days

Content-based image retrieval (CBIR) is the process of retrieval of images from a database that are similar to a query image, using measures derived from the images themselves, rather than relying on accompanying text or annotation. To achieve CBIR, the contents of the images need to be characterized by quantitative features; the features of the query image are compared with the features of each image in the database and images having high similarity with respect to the query image are retrieved and displayed. CBIR of medical images is a useful tool and could provide radiologists with assistance in the form of a display of relevant past cases. One of the challenging aspects of CBIR is to extract features from the images to represent their visual, diagnostic, or application-specific information content. In this book, methods are presented for preprocessing, segmentation, landmarking, feature extraction, and indexing of mammograms for CBIR. The preprocessing steps include anisotropic diffusion and the Wiener filter to remove noise and perform image enhancement. Techniques are described for segmentation of the breast and fibroglandular disk, including maximum entropy, a moment-preserving method, and Otsu's method. Image processing techniques are described for automatic detection of the nipple and the edge of the pectoral muscle via analysis in the Radon domain. By using the nipple and the pectoral muscle as landmarks, mammograms are divided into their internal, external, upper, and lower parts for further analysis. Methods are presented for feature extraction using texture analysis, shape analysis, granulometric analysis, moments, and statistical measures. The CBIR system presented provides options for retrieval using the Kohonen self-organizing map and the k-nearest-neighbor method. Methods are described for inclusion of expert knowledge to reduce the semantic gap in CBIR, including the query point movement method for relevance feedback (RFb). Analysis of performance is described in terms of precision, recall, and relevance-weighted precision of retrieval. Results of application to a clinical database of mammograms are presented, including the input of expert radiologists into the CBIR and RFb processes. Models are presented for integration of CBIR and computer-aided diagnosis (CAD) with a picture archival and communication system (PACS) for efficient workflow in a hospital.

Introduction to Biomedical Engineering (Hardcover, 3rd edition): John Enderle, Joseph Bronzino Introduction to Biomedical Engineering (Hardcover, 3rd edition)
John Enderle, Joseph Bronzino
R1,770 R1,674 Discovery Miles 16 740 Save R96 (5%) Ships in 10 - 15 working days

Introduction to Biomedical Engineering is a comprehensive survey text for biomedical engineering courses. It is the most widely adopted text across the BME course spectrum, valued by instructors and students alike for its authority, clarity and encyclopedic coverage in a single volume. Biomedical engineers need to understand the wide range of topics that are covered in this text, including basic mathematical modeling; anatomy and physiology; electrical engineering, signal processing and instrumentation; biomechanics; biomaterials science and tissue engineering; and medical and engineering ethics. Enderle and Bronzino tackle these core topics at a level appropriate for senior undergraduate students and graduate students who are majoring in BME, or studying it as a combined course with a related engineering, biology or life science, or medical/pre-medical course. * NEW: Each chapter in the 3rd Edition is revised and updated, with new chapters and materials on compartmental analysis, biochemical engineering, transport phenomena, physiological modeling and tissue engineering. Chapters on peripheral topics have been removed and made avaialblw online, including optics and computational cell biology. * NEW: many new worked examples within chapters * NEW: more end of chapter exercises, homework problems

* NEW: Image files from the text available in PowerPoint format for adopting instructors * Readers benefit from the experience and expertise of two of the most internationally renowned BME educators * Instructors benefit from a comprehensive teaching package including a fully worked solutions manual

* A complete introduction and survey of BME * NEW: new chapters on compartmental analysis, biochemical engineering, and biomedical transport phenomena

* NEW: revised and updated chapters throughout the book feature current research and developments in, for example biomaterials, tissue engineering, biosensors, physiological modeling, and biosignal processing. * NEW: more worked examples and end of chapter exercises

* NEW: Image files from the text available in PowerPoint format for adopting instructors * As with prior editions, this third edition provides a historical look at the major developments across biomedical domains and covers the fundamental principles underlying biomedical engineering analysis, modeling, and design

*bonus chapters on the web include: Rehabilitation Engineering and Assistive Technology, Genomics and Bioinformatics, and Computational Cell Biology and Complexity."

Post-genomic Approaches in Cancer and Nano Medicine (Hardcover): Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra Post-genomic Approaches in Cancer and Nano Medicine (Hardcover)
Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
R2,135 Discovery Miles 21 350 Ships in 10 - 15 working days

Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. A substantial proportion of human genes show alternative splicing and mis-regulation of Pre-mRNA splicing is seen in several cancers. This book further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing, and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving towards revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs. Technical topics discussed in the book include: * Alternative splicing and cancer * Cancer imaging * Nanomaterials in infectious diseases * Nanomedicine in oxidative stress and cancer * Nanoparticle based drug delivery systems

Nano-biomedical Engineering 2012 - Proceedings Of The Tohoku University Global Centre Of Excellence Programme (Hardcover, New):... Nano-biomedical Engineering 2012 - Proceedings Of The Tohoku University Global Centre Of Excellence Programme (Hardcover, New)
Takami Yamaguchi
R5,628 Discovery Miles 56 280 Ships in 10 - 15 working days

This book focuses on nano-biomedical engineering, the most important key technology in the world in the 21st century. It covers virtually everything within current and future research and the development of biomedical engineering. It follows four groups within the field, namely nano-biomechanics, nano-bioimaging, nano-biodevices, and nano-biointervention.

Introduction To Metabolic And Cellular Engineering, An (Paperback, Second Edition): Sonia Del Carmen Cortassa, Miguel Antonio... Introduction To Metabolic And Cellular Engineering, An (Paperback, Second Edition)
Sonia Del Carmen Cortassa, Miguel Antonio Aon, Juan Carlos Aon, Alberto Alvaro Iglesias, David Lloyd
R1,283 Discovery Miles 12 830 Ships in 10 - 15 working days

Metabolic and Cellular Engineering (MCE) is more than an exciting scientific enterprise. It has become the cornerstone for coping with the challenges ahead of mankind. Continuous developments, new concepts, and technological innovations will enable us to deal with emerging challenges, and solve problems once thought impossible ten years ago. Challenges in MCE are broad- from unraveling fundamental aspects of cellular function to meeting unsatiated energy and food demands that are rising in parallel with population growth.In charting the progress of MCE during the last decade, we could not help but feel in awe of the enormous strides of progress made from the nascent Metabolic Engineering to the Systems Bioengineering of today. The burgeoning availability of genomic sequences from diverse species has been spectacular. It has become the engine that drives the genetic means for the modification of existing organisms and the generation of synthetic, man-made ones. From the initial attempts at purposeful genetic modification of a cell for the production of valuable compounds, we have now moved on to changing microbes genetically or metabolically.The arsenal of experimental and theoretical tools available for Metabolic and Cellular Engineering has expanded enormously, driven by the re-emergence of Physiology as Systems Biology. The revival of the concept of networks fueled by new developments has become central to Systems Biology. Networks represent an integrative vision of how processes of disparate nature relate to each other, and as such is becoming a key analytical and conceptual tool for MCE. This book reflects and addresses all these ongoing changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field.

Research as Development - Biomedical Research, Ethics, and Collaboration in Sri Lanka (Hardcover): Salla Sariola, Robert Simpson Research as Development - Biomedical Research, Ethics, and Collaboration in Sri Lanka (Hardcover)
Salla Sariola, Robert Simpson
R1,071 R913 Discovery Miles 9 130 Save R158 (15%) Ships in 10 - 15 working days

In Research as Development, Salla Sariola and Bob Simpson show how international collaboration operates in a setting that is typically portrayed as "resource-poor" and "scientifically lagging." Based on their long-term fieldwork in Sri Lanka, Sariola and Simpson bring into clear ethnographic focus the ways international scientific collaborations feature prominently in the pursuit of global health in which research operates "as" development and not merely "for" it. The authors follow the design, inception, and practice of two clinical trials: one a global health charity funded trial and the other a pharmaceutical industry-sponsored trial. Research as Development situates these two trials within their historical, political and cultural contexts and thus counters the idea that local actors are merely passive recipients of new technical and scientific rationalities. While social studies of clinical trials are beginning to be an established niche in academic writing, Research as Development helps fill important gaps in the literature through its examination of clinical research situated in cultures in low-income settings. Research as Development is noteworthy for the way it highlights the critical and creative role that local researchers play in establishing international collaborations and making them work into locally viable forms. The volume shows how these clinical and research interactions bring about changes in culture, technologies and expertise in Sri Lanka, contexts that have not previously been written about in any detail.

Encyclopedia of Molecular Cell Biology and Molecular Medicine, Volume 3 (Hardcover, 2nd Edition): Robert A. Meyers Encyclopedia of Molecular Cell Biology and Molecular Medicine, Volume 3 (Hardcover, 2nd Edition)
Robert A. Meyers
R9,753 Discovery Miles 97 530 Ships in 10 - 15 working days

This second edition of the "Encyclopedia of Molecular Cell Biology and Molecular Medicine" covers the molecular and cellular basis of life, disease, and therapy at university and professional researcher level. With its 16 volumes, this is the most comprehensive and detailed treatment of molecular cell biology and molecular medicine available today. It represents a single source library for Molecular Biologists Cell Biologist Biochemists Structural Biologists Gene Technologists Developmental Biologists Medicinal Chemists Physicians Biotechnologists Pharmacologists

An Editorial Board composed of renowned experts from all over the world - Nobel laureates, including the 2007 Nobel Prize winner in medicine, Sir Martin Evans, Lasker Award winners and directors of prestigious institutes and university departments - guarantees the high quality and comprehensive scope of this work. All major disciplines comprising and supporting molecular cell biology and molecular medicine are covered in true Encyclopedic detail.

Each of the over 400 articles is conceived as a self-contained treatment and begins with an outline and a keyword section, including definitions. Descriptive illustrations - many in colour -, informative tables and a glossary of basic terms in each volume enable readers to understand articles without the need to consult a dictionary, textbook or other work. Numerous cross-references and a comprehensive bibliography round off every article.

Praise from the reviews:

,,"." It goes without saying that no library can afford to be without this new edition. Everyone working in the areas of molecular biology, genome research, medical science, or clinical research needs to haveaccess to these volumes... "" Angewandte Chemie

,,"." an authoritative reference source of the highest quality... It is extremely well written and well illustrated...""American Reference Books Annual (Library & Information Science Annual - on the first edition)

For further details please visit our homepage at www.meyers-emcbmm.de

Biomarkers and Human Biomonitoring - Volume 1 (Hardcover): Lisbeth Knudsen, Domenico Franco Merlo Biomarkers and Human Biomonitoring - Volume 1 (Hardcover)
Lisbeth Knudsen, Domenico Franco Merlo
R3,574 Discovery Miles 35 740 Ships in 7 - 11 working days

Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern from exposure to endocrine disruptors and the genotoxic compound. Biomarkers of specific exposures to a wide range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, PAHs, dioxins, mercury and arsenic are also discussed. Volume two decribes human biomonitoing of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as effect biomarkers of hemoglobin adducts, germ cells, micronuclei and individual susceptability. The books will be essential reading for toxicologists, environmental scientists and all those working in the safety and risk assessment of chemicals.

Biomarkers and Human Biomonitoring - Volume 2 (Hardcover): Lisbeth Knudsen, Domenico Franco Merlo Biomarkers and Human Biomonitoring - Volume 2 (Hardcover)
Lisbeth Knudsen, Domenico Franco Merlo
R3,519 Discovery Miles 35 190 Ships in 7 - 11 working days

Human biomonitoring has developed from a research tool in occupational and environmental health to identify and quantify exposures to harmful substances in urine and blood. The analytical methods for detection of substances in biological media have considerably improved with smaller detection limits and more precise and specific measurements. Human biomonitoring is a valuable tool in exposure estimation of selected populations and currently used in surveillance programs all over the world. This two volume set provides an overview of current available biomarkers and human biomonitoring programs in environmental health, which is timely given the present debate on adverse health effects from environmental exposures. The books decribe both previous and ongoing studies as well as the newer biomarkers of exposure and effects. Volume one describes current human biomonitoring programs in Germany, Romania, France, Canada, India and Belgium, providing convincing evidence of a global decline in human exposures to lead and increasing concern from exposure to endocrine disruptors and the genotoxic compound. Biomarkers of specific exposures to a wide range of widely used everyday compounds such as phthalates, PFCs, bisphenol A, brominated flame retardants, PAHs, dioxins, mercury and arsenic are also discussed. Volume two decribes human biomonitoing of exposures to environmental tobacco smoke, mycotoxins, physiological stress, hormone activity, oxidative stress and ionizing radiation, as well as effect biomarkers of hemoglobin adducts, germ cells, micronuclei and individual susceptability. The books will be essential reading for toxicologists, environmental scientists and all those working in the safety and risk assessment of chemicals.

Introduction to Instrumentation and Measurements (Paperback, 3rd New edition): Robert B. Northrop Introduction to Instrumentation and Measurements (Paperback, 3rd New edition)
Robert B. Northrop
R1,419 Discovery Miles 14 190 Ships in 10 - 15 working days

Weighing in on the growth of innovative technologies, the adoption of new standards, and the lack of educational development as it relates to current and emerging applications, the third edition of Introduction to Instrumentation and Measurements uses the authors' 40 years of teaching experience to expound on the theory, science, and art of modern instrumentation and measurements (I&M). What's New in This Edition: This edition includes material on modern integrated circuit (IC) and photonic sensors, micro-electro-mechanical (MEM) and nano-electro-mechanical (NEM) sensors, chemical and radiation sensors, signal conditioning, noise, data interfaces, and basic digital signal processing (DSP), and upgrades every chapter with the latest advancements. It contains new material on the designs of micro-electro-mechanical (MEMS) sensors, adds two new chapters on wireless instrumentation and microsensors, and incorporates extensive biomedical examples and problems. Containing 13 chapters, this third edition: Describes sensor dynamics, signal conditioning, and data display and storage Focuses on means of conditioning the analog outputs of various sensors Considers noise and coherent interference in measurements in depth Covers the traditional topics of DC null methods of measurement and AC null measurements Examines Wheatstone and Kelvin bridges and potentiometers Explores the major AC bridges used to measure inductance, Q, capacitance, and D Presents a survey of sensor mechanisms Includes a description and analysis of sensors based on the giant magnetoresistive effect (GMR) and the anisotropic magnetoresistive (AMR) effect Provides a detailed analysis of mechanical gyroscopes, clinometers, and accelerometers Contains the classic means of measuring electrical quantities Examines digital interfaces in measurement systems Defines digital signal conditioning in instrumentation Addresses solid-state chemical microsensors and wireless instrumentation Introduces mechanical microsensors (MEMS and NEMS) Details examples of the design of measurement systems Introduction to Instrumentation and Measurements is written with practicing engineers and scientists in mind, and is intended to be used in a classroom course or as a reference. It is assumed that the reader has taken core EE curriculum courses or their equivalents.

Biomedical Microsystems (Hardcover): Ellis Meng Biomedical Microsystems (Hardcover)
Ellis Meng
R2,323 Discovery Miles 23 230 Ships in 10 - 15 working days

Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications.

Written by an active researcher who was recently named one of Technology Review's Young Innovators Under 35, the book begins with an introduction to the benefits of miniaturization. It then introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author also covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering.

For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. A solutions manual is available for instructors who want to convert this reference to classroom use.

Dose, Benefit, and Risk in Medical Imaging (Hardcover): Lawrence T. Dauer, Bae P. Chu, Pat B. Zanzonico Dose, Benefit, and Risk in Medical Imaging (Hardcover)
Lawrence T. Dauer, Bae P. Chu, Pat B. Zanzonico
R3,556 Discovery Miles 35 560 Ships in 10 - 15 working days

This timely overview of dose, benefit, and risk in medical imaging explains to readers how to apply this information for informed decision-making that improves patient outcomes. The chapters cover patient and physician perspectives, referral guidelines, appropriateness criteria, and quantifying medical imaging benefits. The authors have included essential discussion about radiologic physics in medical imaging, fundamentals of dose and image quality, risk assessment, and techniques for optimization and dose reduction. The book highlights practical implementation aspects with useful case studies and checklists for treatment planning. Clinicians, students, residents, and professionals in medical physics, biomedical engineering, radiology, oncology, and allied disciplines will find this book an essential resource with the following key features: Discusses risk, benefit, dose optimization, safety, regulation, radiological protection, and shared & informed decision-making. Covers regulatory oversight by government agencies, manufacturers, and societies. Highlights best practices for improving patient safety and outcomes. Gives guidelines on doses associated with specific procedures.

Engineering of Micro/Nano Biosystems - Fundamentals & Applications (Hardcover, 1st ed. 2020): Gregory Barbillon, Alain... Engineering of Micro/Nano Biosystems - Fundamentals & Applications (Hardcover, 1st ed. 2020)
Gregory Barbillon, Alain Bosseboeuf, Kukjin Chun, Rosaria Ferrigno, Olivier Francais
R3,758 R3,239 Discovery Miles 32 390 Save R519 (14%) Ships in 10 - 15 working days

This tutorial book offers an in-depth overview of the fundamental principles of micro/nano technologies and devices related to sensing, actuation and diagnosis in fluidics and biosystems. Research in the MEMS/NEMS and lab-on-chip fields has seen rapid growth in both academic and industrial domains, as these biodevices and systems are increasingly replacing traditional large size diagnostic tools. This book is unique in describing not only the devices and technologies but also the basic principles of their operation. The comprehensive description of the fabrication, packaging and principles of micro/nano biosystems presented in this book offers guidance for researchers designing and implementing these biosystems across diverse fields including medical, pharmaceutical and biological sciences. The book provides a detailed overview of the fundamental mechanical, optical, electrical and magnetic principles involved, together with the technologies required for the design, fabrication and characterization of micro/nano fluidic systems and bio-devices. Written by a collaborative team from France and Korea, the book is suitable for academics, researchers, advanced level students and industrial manufacturers.

Implementing Biomedical Innovations into Health, Education, and Practice - Preparing Tomorrow's Physicians (Paperback):... Implementing Biomedical Innovations into Health, Education, and Practice - Preparing Tomorrow's Physicians (Paperback)
James O. Woolliscroft
R2,177 Discovery Miles 21 770 Ships in 10 - 15 working days

Our increased understanding of health and disease coupled with major technologic advances has resulted in rapid and significant changes in the practice of medicine. How we prepare physicians for clinical practice 20, 30, or 40 years from now is of paramount importance to medical educators, to the future professionals, and to society at large. Implementing Biomedical Innovations into Health, Education, and Practice delves into this important question, discussing the effects of precision medicine, bioinformatics, biologic and environmental forces, and societal shifts on the physician's approach to diagnosis and therapy. The author interviewed world-renowned physicians, medical educators, healthcare leaders, and research professionals-their insights and quotes are woven throughout the narrative. Professionally illustrated, this relevant resource is a must-have for all medical professionals who incorporate technology and biomedical innovations in their research and clinical practice. It encourages thoughtful analysis on adapting and developing the foundational knowledge, skills, and aptitudes of future physicians and other healthcare professionals, and it belongs in your library. "Having completed deanship at one of America's leading medical schools, Jim Woolliscroft produces an insightful, contemplative projection of the likely skill and behavioral needs of the physician workforce for the mid-21st century...The result is a playbook for physician training that responds effectively to the daunting challenges faced in the coming transformation of the role of physicians in protecting the health of our nation." James L. Madara, MD, CEO, American Medical Association "Dr. Woolliscroft's provocative new book will become must reading for all who are serious about educating the next generation of physicians and health care leaders. Leveraging his own experience as a consummate educator and interviews with numerous thought leaders, he identifies the uncertainties, challenges and disruptions to the practice of medicine in the decades ahead. The implications and imperatives for the coming generations of physicians are compelling and of critical importance for care givers, policy makers, and most pointedly educators in the U.S. and around the world." Gary S. Kaplan MD, Chairman and CEO, Virginia Mason Health System "This ambitious masterpiece, by one of the leading medical educators of our time, fully captures the ongoing changes and disruptions in medicine today, and how they will influence the care of patients and the training of young physicians in the future." Eric Topol, MD, Executive Vice President, Scripps Research, Author of Deep Medicine

Nanoparticles in Polymer Systems for Biomedical Applications (Hardcover): Jince Thomas, Sabu Thomas, Nandakumar Kalarikkal,... Nanoparticles in Polymer Systems for Biomedical Applications (Hardcover)
Jince Thomas, Sabu Thomas, Nandakumar Kalarikkal, Jiya Jose
R3,168 Discovery Miles 31 680 Ships in 10 - 15 working days

The volume includes presentations of technological and research accomplishments along with novel approaches in nanomedicine and nanotechnology. It explores the different types of nanomedicinal drugs with their production and commercial significance. Other topics discussed are the use of natural and synthetic nanoparticles for the production of drugs, different types of nanoparticles systems, drug carriers, wound-healing antimicrobial activity, effects of natural materials in nanomedicine, and toxicity of nanoparticles. The valuable information presented in this volume will help to keep those in this field up to date on the key findings, observations, and fabrication of drugs related to nanomedicine and nanotechnology. With chapters written by prominent researchers from academia, industry, and government and private research laboratories across the world, the book will prove to be a rich resource.

Health Care Engineering Part I - Clinical Engineering and Technology Management (Paperback): Monique Frize Health Care Engineering Part I - Clinical Engineering and Technology Management (Paperback)
Monique Frize
R786 Discovery Miles 7 860 Ships in 7 - 11 working days

Part I: The introduction presents the evolution of clinical engineering in North America. The first chapter describes the health care delivery systems in Canada and in the US. This is followed by examples of various approaches used to measure physiological variables in humans, either for the purpose of diagnosis or monitoring potential disease conditions; a brief description of sensor technologies is included. The function and role of the clinical engineer in managing medical technologies in industrialized and in developing countries are presented, followed by a chapter on how to minimize liability and develop a quality assurance program for technology management. The next chapter covers technical, social, and ethical issues related to telemedicine. A chapter discusses the impact of technology on health care and the final chapter is on the technology assessment process. Part II: The introduction discusses adverse events and medical errors. The next chapter presents how information technologies can help to reduce their occurrence. Another topic is on medical databases, data collection, storage and retrieval. A chapter on electronic medical records follows. The safe and effective use of technologies is discussed. Medical applications of infrared imaging are included. Principles to consider when designing medical devices are discussed. The two parts consolidate material that supports two courses on technology development and management issues in health care institutions. It can be useful for anyone involved in design, development, or research, whether in industry, hospitals, government, or in universities and colleges. It is not intended to cover all topics in depth but rather to provide an overview of the topics and sources where additional information can be found.

Biomedical Engineering Entrepreneurship (Hardcover): Jen-Shih Lee Biomedical Engineering Entrepreneurship (Hardcover)
Jen-Shih Lee
R2,066 Discovery Miles 20 660 Ships in 10 - 15 working days

This book is written for undergraduate and graduate students in biomedical engineering wanting to learn how to pursue a career in building up their entrepreneur ventures. Practicing engineers wanting to apply their innovations for healthcare will also find this book usefulThe 21st century is the "Biotech Century" where many nations are investing heavily in biotechnology. As a result, tremendous business opportunities exist for biomedical engineering graduates who are interested in becoming successful entrepreneurs. However, many challenges await these entrepreneurs intending to invent safe and effective devices and drugs to prevent, diagnose, alleviate and cure diseases.In this publication, many examples of innovations in biomedical engineering are covered, from the conceptualization stage to successful implementation and commercialization. Part I teaches working and would-be biomedical engineers to assess how well their innovations and their team can succeed; Part II will guide budding entrepreneurs to launch their ventures to the point of pre-production models. Other important aspects like financing, negotiations, leading by example, manufacturing, marketing, venture and globalization are covered in Part III. Two concluding chapters, with excerpts from leaders in community, education and industries, touch on the growth and investment in biomedical engineering entrepreneurship.

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