This book provides the state-of-the-art survey of green techniques in preparation of different classes of nanomaterials, with an emphasis on the use of renewable sources. Key topics covered include fabrication of nanomaterials using green techniques as well as their properties and applications, the use of renewable sources to obtain nanomaterials of different classes, from simple metal and metal oxide nanoparticles to complex bioinspired nanomaterials, economic contributions of nanotechnology to green and sustainable growth, and more. This is an ideal book for students, lecturers, researchers and engineers dealing with versatile (mainly chemical, biological, and medical) aspects of nanotechnology, including fabrication of nanomaterials using green techniques and their properties and applications.

This book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational approaches in the field of cardiovascular medicine, e.g. simulation of turbulence in cardiovascular flow, modeling of artificial textile-reinforced heart valves, and new strategies for reducing the computational cost in the fluid-structure interaction modeling of hemodynamics. The book's last three parts address experimental observations, numerical tests, computational simulations, and multiscale modeling approaches to dentistry, orthopedics and otology. Written by leading experts, the book reflects the remarkable advances that have been made in the field of medicine, the life sciences, engineering and computational mechanics over the past decade, and summarizes essential tools and methods (such as virtual prototyping of medical devices, advances in medical imaging, high-performance computing and new experimental test devices) to enhance medical decision-making processes and refine implant design. The contents build upon the International Conference on Biomedical Technology 2015 (ICTB 2015), the second ECCOMAS thematic conference on Biomedical Engineering, held in Hannover, Germany in October 2015.

Nonhuman primates have played critical roles in biomedical research, and they are among the few animals whose use in research continues to increase. The scienti?c value of nonhuman primates derives from their close phylogenetic proximity to man and their consequent anatomic, physiologic, and genetic similarities to man. Only nonhuman primates can provide adequate models for many complex physiological and disease processes of humans. The baboon is a relative newcomer to the repertoire of nonhuman primates used in biomedical research. However, in less than 50 years since its ?rst use in the U. S. , it has become one of the most popular laboratory primate species. It is larger than the other widely used monkey species, making it advantageous for many types of experiments and technological developments. It is extraordinarily hardy and highly fecund in captivity. It closely resembles humans in a variety of physiological and disease processes, such as cholesterol metabolism, early stages of atherosclerosis, and alcoholic liver disease. Its chromosomes closely resemble those of humans, and many genes of the two species lie in the same chromosomal order. Among all primates, baboons are the most widely used models for the genetics of susceptibility to complex diseases and they are the ?rst nonhuman primate for which a framework genetic linkage map was established. In addition, the baboon genome is currently being sequenced, and as a result the utility of this species for biomedical research will be dramatically increased.

Tissue engineering is an extremely important area. It generally involves the use of materials and cells with the goal of trying to understand tissue function and some day enabling virtually any tissue or organ on the body to be made de novo. To achieve this very important long-range objective requires research in many areas. This book... addresses many of these important topics, and the chapters provide a foundation for the understanding and development of the cell-based systems needed for tissue engineering
.
"Dr. Robert S. Langer
Institute Professor at Massachusetts Institute of Technology, from his Foreword to this book"
Key Features
* Brings together fundamental knowledge in each of the key topics that those studying and working in tissue engineering need to understand and master
* Surpasses other books that provide a collection of research and protocols, by presenting an insightful examination of the different aspects of tissue engineering
* Its textbook approach enables readers to develop knowledge and understanding swiftly by introducing key topics and providing supporting analysis
* Color illustrations, clear examples, case studies, chapter exercises plus frequent Classical and State of the Art Experiment overviews set topics in context for a wide range of readers
* Meets the needs of a wide range of engineering and life sciences students, including biomedical engineers, chemical and process engineers, materials scientists, biologists and medical students
Tissue Engineering is a comprehensive introduction to the engineering and biological aspects of this critical subject. With contributions from internationally renowned authors, it provides abroad perspective on tissue engineering for students coming to the subject for the first time. Key topics covered include stem cells; morphogenesis and cellular signaling; the extracellular matrix; biocompatibility; scaffold design and fabrication; controlled release strategies; bioreactors; tissue engineering of skin, cartilage, bone and organ systems; and ethical issues.
- Covers all the essentials from tissue homeostasis and biocompatibility to cardiovascular engineering and regulations
- 24 chapters from internationally recognized authors, provide a comprehensive introduction for engineers and life scientists, including biomedical engineers, chemical and process engineers, materials scientists, biologists and medical students
- Full colour throughout, with clear development of understanding through frequent examples, experimental approaches and the latest research and developments.

Computational Intelligence (CI) and Bioprocess are well-established research areas which have much to offer each other. Under the perspective of the CI area, Biop- cess can be considered a vast application area with a growing number of complex and challenging tasks to be dealt with, whose solutions can contribute to boosting the development of new intelligent techniques as well as to help the refinement and s- cialization of many of the already existing techniques. Under the perspective of the Bioprocess area, CI can be considered a useful repertoire of theories, methods and techniques that can contribute and offer interesting alternative approaches for solving many of its problems, particularly those hard to solve using conventional techniques. Although throughout the past years CI and Bioprocess areas have accumulated substantial specific knowledge and progress has been quick and with a high degree of success, we believe there is still a long way to go in order to use the potentialities of the available CI techniques and knowledge at their full extent, as tools for supporting problem solving in bioprocesses. One of the reasons is the fact that both areas have progressed steadily and have been continuously accumulating and refining specific knowledge; another reason is the high level of technical expertise demanded by each of them. The acquisition of technical skills, experience and good insights in either of the two areas is very demanding and a hard task to be accomplished by any professional.

This book presents the Proceedings of ICON-2019, an international meeting exclusively dedicated to nanostructured materials in medicinal applications. The conference emphasized the recent advances in multidisciplinary research on processing, morphology, structure and properties of nanostructured materials and their applications in various medicinal fields. The papers encompass basic studies and applications and address topics of novel issues, difficulties, and breakthroughs in the field of nanomedicine in cancer, tuberculosis, tissue engineering, regenerative medicine etc.

Drawing on such process thinkers as Whitehead, Deleuze and Stengers, Innovation and Biomedicine develops a powerful framework for the analysis of Biomedical Innovation. With its sustained focus on the Pre-Exposure Prophylactic pill (PrEP) for the prevention of HIV infection, the volume explores the ethical, medical and political elements entailed in the pill's testing through offshore randomized control trials (RCTs). To this end, the key concept of 'eventuation' is elaborated and deployed in the scrutiny of the 'gold standard' status of RCTs, the role of ethics in RCTs, and the enactment of the PrEP pill as a singular entity. Further, the authors engage with affective, topological and virtual dimensions to show how PrEP's eventuation also allows for new scientific and ethical questions to be crafted. Innovation and Biomedicine is a major contribution to science and technology studies, medical sociology, and the multi-disciplinary study of HIV.

The book provides comprehensive information about the different aspects of veterinary nutrition in tropical countries.The introductory chapter discuss the importance of nutrition, feeds and feeding of balanced and optimum feeds specifically required for the sustenance of life. The second chapter, discusses briefly the history of research in animal nutrition.The book further talks about the relationship between the environment and nutrition in animals; the chemical composition of plants and animals; and the various sources of feed for animals. It provides details on the different phases of life cycle in animals, and the effect of nutrition on the performance. Various Nutrients and its importance in livestock nutritionand production has been illustrated in details. Various nutrients such as water, carbohydrate, protein, fats, vitamins, minerals etc are individually dealt in a separate chapter. The digestive system,digestion and metabolism of carbohydrates, protein and fats in ruminant and non ruminant livestock have been illustrated. A dedicated chapter fully describes the activity of enzymes which are directly involved in nutrition. Also this book deals with the harmful components of animal feed which are found mainly in the unconventional feeds. The books also provide chapters like partitioning of feed& energy and also the therapeutic and clinical nutrition which are very importantfor the under graduate & post graduate students and researchers of animal nutrition and livestock production and management. This book is useful for researchers, undergraduate and post graduate students studying veterinary sciences, animal husbandry, zoology and biochemistry.

This book presents as its main subject new models in mathematical neuroscience. A wide range of neural networks models with discontinuities are discussed, including impulsive differential equations, differential equations with piecewise constant arguments, and models of mixed type. These models involve discontinuities, which are natural because huge velocities and short distances are usually observed in devices modeling the networks. A discussion of the models, appropriate for the proposed applications, is also provided.

Sleep medicine has been developing for more than 40 years. The current concepts in sleep technology are mainly centered on polysomnography (PSG) and issues related to sleep technicians. However, the editorsbelieve that the true value of technology is revealed only when benefits to humanity are manifest. To this end, they endeavor to create a new era in sleep technology, one that will improve the quality of people's sleep and daily lives.

This edited book, Introduction to Modern Sleep Technology, provides a comprehensive reference volume to the latest advancements in the area of Sleep Technology. It offers an excellent range of insights and opinions from leading researchers and experts in multiple disciplines spanning academia, clinical practice and industry. Up-to-date insights into the current research topics in this field are featured in addition to the latest technological advances with reference to appropriate working examples.

Thecurrentbookcombines the five dimensions of knowledge, i.e., sleep medicine, clinical psychology engineering, industrial design and technology management to ensure the content is applicable to people's daily lives.

This edited book, Introduction to Modern Sleep Technology, provides a comprehensive reference volume to the latest advancements in the area of Sleep Technology. It offers an excellent range of insights and opinions from leading researchers and experts in multiple disciplines spanning academia, clinical practice and industry. Up-to-date insights into the current research topics in this field are featured in addition to the latest technological advances with reference to appropriate working examples.

Thecurrentbookcombines the five dimensions of knowledge, i.e., sleep medicine, clinical psychology engineering, industrial design and technology management to ensure the content is applicable to people's daily lives.

Thecurrentbookcombines the five dimensions of knowledge, i.e., sleep medicine, clinical psychology engineering, industrial design and technology management to ensure the content is applicable to people's daily lives.

This book comprises select peer-reviewed papers presented at the International Conference on Biomedical Engineering Science and Technology: Roadway from Laboratory to Market (ICBEST 2018) organized by Department of Biomedical Engineering, National Institute of Technology Raipur, Chhattisgarh, India. The book covers latest research in a wide range of biomedical technologies ranging from biomechanics, biomaterials, biomedical instrumentation to tele-medicine, internet of things, bioinformatics, medical signal and image processing. The contents aim to bridge the gap between laboratory research and feasible market products by identifying potential technologies to enhance functionalities of diagnostic and therapeutic devices. The book will be of use to researchers, biomedical engineers, as well as medical practitioners.

This book is aimed at all those who are interested to understand the current research going on in nanomaterial science from the perspectives of biomedical, sensorial and energy applications including all aspects of physical chemist, chemical engineers and material scientist. Nanoscience and nanotechnology are at the forefront of modern research. The fast growing economy in this area requires experts with outstanding knowledge of nanoscience in combination with the skills to apply this knowledge in new products. A multidisciplinary scientific education is crucial to provide industry and research institutes with top quality experts who have a generic background in the different sub disciplines such as electronics, physics, chemistry, material science, biotechnology. The book covers recent advancement in nanoscience and nanotechnology particularly highlights the utilization of different types of nanomaterials in biomedical field, sensor and in the energy application. On the other hand, it leads the reader to the most significant recent developments in research. It provides a broad and in-depth coverage of the nanoscale materials and its depth significant applications.

Nanoneuroscience is the study of computationally relevant biomolecules found inside neurons. Because of recent technological advances at the nanometer scale, scientists have at their disposal increasingly better ways to study the brain and the biophysics of its molecules. This book describes how biomolecules contribute to the operations of synapses and perform other computationally relevant functions inside dendrites. These biomolecular operations considerably expand the brain-computer analogy - endowing each neuron with the processing power of a silicon-based multiprocessor. Amazingly, the brain contains hundreds of billions of neurons.

This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as cortisol. The presented models provide a powerful diagnostic tool but may also enable treatment via long-term glucose regulation in diabetics through closed-look model-reference control using frequent insulin infusions, which are administered by implanted programmable micro-pumps. This research volume aims at presenting state-of-the-art research on this subject and demonstrating the potential applications of modeling to the diagnosis and treatment of diabetes. The target audience primarily comprises research and experts in the field but the book may also be beneficial for graduate students.

This collection of recent activities provides researchers and scientists with the latest trends in characterization and developments of biosystems and biomaterials. Well known experts present their research in materials for drug delivery, dental implants and filling materials, biocompatible membranes, bioactive surface coatings and bio-compatible and eco-sustainable building materials. In The book covers also topics like microorganisms, the human eye, the musculoskeletal system and human body parts.

Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to diverse therapeutic applications of light, known collectively as phototherapies. It facilitates your understanding of human diseases caused by light, the rationale for photoprotection, and major applications of phototherapy in clinical practice. The handbook begins with a series of historical vignettes of pioneers from the last two centuries. It also presents the fundamentals of physics and biology as applied to photomedicine. It next examines conditions and diseases caused by light, including skin cancer, dermatoses, and immunosuppression. The remainder of the book focuses on the most important clinical therapeutic applications of different kinds of light that vary in both wavelength and intensity. The book discusses ultraviolet phototherapy for skin diseases and infections and presents the basic science of photodynamic therapy and its use in cancer therapy and other medical specialties. It then covers mechanistic studies and clinical applications of low-level laser (light) therapy as well as the use of high power or surgical laser therapy in specialties, such as dentistry and dermatology. The book concludes with a collection of miscellaneous types of phototherapy.

This book is a collection of articles presented by researchers and practitioners, including engineers, biologists, health professionals and informatics/computer scientists, interested in both theoretical advances and applications of information systems, artificial intelligence, signal processing, electronics and other engineering tools in areas related to biology and medicine in the All India Seminar on Biomedical Engineering 2012 (AISOBE 2012), organized by The Institution of Engineers (India), Jabalpur Local Centre, Jabalpur, India during November 3-4, 2012. The content of the book is useful to doctors, engineers, researchers and academicians as well as industry professionals.

This book provides an expert view into the current technologies that are revolutionizing the field of solid organ transplantation. This unique book provides insight into progress made in areas spanning robotic surgery to tissue engineering and also gives a glimpse into what may lie ahead for this innovative specialty. Topics covered include nanotherapy, machine perfusion, artificial organ development, robotics in transplant surgery, mobile health technology, stem cell therapy, and ex vivo repair of organs. This is an ideal book for biomedical engineers, physicians and surgeons, general and transplant surgeons, medical students, medical and surgical trainees, and transplant procurement technicians.

This thesis presents various applications of graphene-based nanomaterials, especially in biomedicine. Graphene and its derivatives have gained enormous attention from scientists in all fields of study due to many unprecedented properties. The initial scientific attention was focused on the development of transparent flexible electrodes by exploiting two-dimensional graphene film's extraordinary electrical and physical properties. Recently, given an increasing evidence of dispersed graphene-based nanomaterials' biocompatibility, researchers have endeavored to employ these materials in other studies relevant to biomedical technologies. In this respect, the thesis provides a comprehensive review on the synthesis, toxicity, and a few of the key biomedical applications in the first chapter. The following chapter discusses the use of a graphene film as a novel catalyst to oxidatively destroy phenols, which are known to be potentially mutagenic and carcinogenic. Finally, and most importantly, the last chapter introduces the therapeutic role of graphene quantum dots, the smallest graphene-based nanomaterials, for Parkinson's disease. The results are promising for the use of graphene quantum dots as the basis of future clinical drug candidates for neurodegenerative disorders.

One of the greatest challenges for mechanical engineers is to extend the success of computational mechanics to fields outside traditional engineering, in particular to biology, biomedical sciences, and medicine.This book is an opportunity for computational biomechanics specialists to present and exchange opinions on the opportunities of applying their techniques to computer-integrated medicine.

"Computational Biomechanics for Medicine: Deformation and Flow" collects the papers from the Medical Image Computing and Computer Assisted Intervention conference (MICCAI 2011) dedicated to research in the field of medical image computing and computer assisted medical interventions. The topics covered include: medical image analysis, image-guided surgery, surgical simulation, surgical intervention planning, disease prognosis and diagnostics, injury mechanism analysis, implant and prostheses design, andmedical robotics."

Nanorobots represent a nanoscale device where proteins such as DNA, carbon nanotubes could act as motors, mechanical joints, transmission elements, or sensors. When these different components were assembled together they can form nanorobots with multi-degree-of-freedom, able to apply forces and manipulate objects in the nanoscale world. Design, Modeling and Characterization of Bio-Nanorobotic Systems investigates the design, assembly, simulation, and prototyping of biological and artificial molecular structures with the goal of implementing their internal nanoscale movements within nanorobotic systems in an optimized manner.

This book collects the state-of-art and new trends in image analysis and biomechanics. It covers a wide field of scientific and cultural topics, ranging from remodeling of bone tissue under the mechanical stimulus up to optimizing the performance of sports equipment, through the patient-specific modeling in orthopedics, microtomography and its application in oral and implant research, computational modeling in the field of hip prostheses, image based model development and analysis of the human knee joint, kinematics of the hip joint, micro-scale analysis of compositional and mechanical properties of dentin, automated techniques for cervical cell image analysis, and biomedical imaging and computational modeling in cardiovascular disease.

The book will be of interest to researchers, Ph.D students, and graduate students with multidisciplinary interests related to image analysis and understanding, medical imaging, biomechanics, simulation and modeling, experimental analysis

This book presents the most important aspects of analysis of dynamical processes taking place on the human body surface. It provides an overview of the major devices that act as a prevention measure to boost a person's motivation for physical activity. A short overview of the most popular MEMS sensors for biomedical applications is given. The development and validation of a multi-level computational model that combines mathematical models of an accelerometer and reduced human body surface tissue is presented. Subsequently, results of finite element analysis are used together with experimental data to evaluate rheological properties of not only human skin but skeletal joints as well. Methodology of development of MOEMS displacement-pressure sensor and adaptation for real-time biological information monitoring, namely "ex vivo" and "in vitro" blood pulse type analysis, is described. Fundamental and conciliatory investigations, achieved knowledge and scientific experience about biologically adaptive multifunctional nanocomposite materials, their properties and synthesis compatibility, periodical microstructures, which may be used in various optical components for modern, productive sensors' formation technologies and their application in medicine, pharmacy industries and environmental monitoring, are presented and analyzed. This book also is aimed at research and development of vibrational energy harvester, which would convert ambient kinetic energy into electrical energy by means of the impact-type piezoelectric transducer. The book proposes possible prototypes of devices for non-invasive real-time artery pulse measurements and micro energy harvesting.

This book discusses the design of the new mobility assistive information and communication technologies (ICT) devices for the visually impaired. The book begins with a definition of the space concept, followed by the concept of interaction with a space during mobility and this interaction characteristics. The contributors will then examine the neuro-cognitive basis of space perception for mobility and different theories of space perception. The text presents the existing technologies for space perception (sense recovery with stem and iPS cells, implants, brain plasticity, sensory substitution devices, multi modal technologies, etc.), the newest technologies for mobility assistance design, the way the feedback on environment is conveyed to the end-user. Methods for formative and summative evaluations of the mobility devices will also be discussed. The book concludes with a look to the future trends in research and technology development for mobility assistive information and communication technologies.

Lanthanide-Doped Luminescent Nanomaterials reviews the latest advances in the development of lanthanide-doped luminescent inorganic nanoparticles for potential bioapplications. This book covers the chemical and physical fundamentals of these nanoparticles, such as the controlled synthesis methodology, surface modification chemistry, optical physics, and their promising applications in diverse bioassays, with an emphasis on heterogeneous and homogeneous in-vitro biodetection of tumor biomarkers. This book is intended for those readers who are interested in systematically understanding the materials design strategy, optical behavior of lanthanide ions, and practical bioapplications of lanthanide nanoparticles. It primarily focuses on the interdisciplinary frontiers in chemistry, physics and biological aspects of luminescent nanomaterials. All chapters were written by scientists active in this field and for a broad audience, providing both beginners and advanced researchers with comprehensive information on the subject. Xueyuan Chen is a Professor at Fujian Institute of Research on the Structure of Matter (FJIRSM), Chinese Academy of Sciences. Yongsheng Liu is a Research Associate Professor at FJIRSM, Chinese Academy of Sciences. Datao Tu is a Research Assistant Professor at FJIRSM, Chinese Academy of Sciences.