Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors

Abiotic Stress and Legumes: Tolerance and Management is the first book to focus on the ability of legume plants to adapt effectively to environmental challenges. Using the -omic approach, this book takes a targeted approach to understanding the methods and means of ensuring survival and maximizing the productivity of the legume plant by improving tolerance to environmental /abiotic stress factors including drought, temperature change, and other challenges. The book presents a comprehensive overview of the progress that has been made in identifying means of managing abiotic stress effects, specifically in legumes, including the development of several varieties which exhibit tolerance through high yield using transcriptomic, proteomic, metabolomic and ionomic approaches. Further, exogenous application of various stimulants such as plant hormones, nutrients, sugars, and polyamines has emerged as an alternative strategy to improve productivity under these environmental challenges. Abiotic Stress and Legumes: Tolerance and Management examines these emerging strategies and serves as an important resource for researchers, academicians and scientists, enhancing their knowledge and aiding further research.

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part A Volume 184, highlights many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. Emitting light is a fascinating photophysical phenomenon, its different forms have brought the attention of various disciplines of natural sciences for centuries. In the modern era of scientific generation, short-lived fluorescence light and its long-lived counterpart phosphorescence light has been employed for several chemo-sensing, bio-sensing, and bioimaging applications. The aggregation induced emission (AIE) phenomenon has appeared as a wand of modern science to convert aggregation-caused quenching (ACQ) materials into AIE active materials for a wide range of biomedical applications including biosensing, bioimaging and localization of molecules for better understanding of molecular mechanisms. This volume covers a wide range of topics which are not currently available in a single volume, including ACQ & AIE concept development; intracellular pH, temperature and viscosity sensing; imaging of cell membrane, lipid droplet, lysosome, and mitochondria; biosensing and Imaging of bacteria; nucleus and nucleic acid imaging.

Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

Analysis of Chemical Residues in Agriculture presents a focused, yet comprehensive guide on how to identify, evaluate and analyze the wide range of chemicals that impact our food production system. The book presents a variety of analytical technologies and methods in order to help professionals, researchers, and graduate and undergraduate students understand chemical residues in agriculture and apply them to applications for the detection and quantification of chemical residues - both organic and inorganic - in several agricultural matrices, including crops, fruits, meat, food, feed, soil and water. Agriculture remains one of the most strategic sectors for the global economy and well-being. However, it is seen as a source of environmental and health concerns mainly due to the high amount of pesticides and fertilizers used in production systems around the world; moreover, a thorough understanding of the topic is necessary when we consider livestock production systems also apply large amounts of veterinary drugs to treat illness and promote increases in productivity.

Biological Experiments in Space: 30 Years Investigating Life in Space Orbit covers investigations of plant, algae, animals, fish, microorganisms and tissue cultures on space flights, beginning with the first orbital space station on Salyut 1. The book includes results on the influence of the entire complex of physical factors associated with spaceflight on biological systems, including analysis of the impact of microgravity on organisms, as well as the effects of electric and magnetic fields. This book offers important insights for researchers of space biology and astrobiology, as well as space agency and industry specialists developing future space stations and missions. Lack of gravity, temperature and chemical gradients, magnetic and electrical fields, spectral composition and intensity of light, and high-energy cosmic radiation influence many important metabolic and physiological processes in animals, plants, and microorganisms, as well as transfer phenomena in and around them. Success of future space exploration depends on understanding the effects of these factors on biological organisms and developing appropriate countermeasures, aimed at improving growth, development, and reproduction in microgravity.

mRNA 3' End Processing and Stability, Volume 655 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

Advances in Clinical Chemistry, Volume 103, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.

Curing Genetic Diseases through Genome Reprogramming, Volume 182 captures an historic moment in the field of gene therapy-the dawn of a new age in which the dream of curing genetic diseases has become realizable. The volume presents the most clinically advanced gene therapy and genome editing approaches for the treatment of genetic diseases in specific organs, including difficult therapeutic targets, futuristic ideas of genetic interventions, and large scale human genome repair. An initial chapter addresses the complex ethical aspects involved in the very idea of modifying the human genome.

Advances in Clinical Chemistry, Volume 104, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.

Transporters and Plant Osmotic Stress focuses on the potential negative impact of abiotic stresses on plant health and crop yield. The book focuses on the current state of knowledge of the biochemical and molecular regulation of several classes of membrane transporters during different osmotic stresses and their probable mechanisms of operation in plant stress tolerance. The comprehensive discussion presented in this book highlights steps appropriate for mitigating multiple forms of abiotic stresses utilizing transporter proteins. Edited by leading experts and authored by top researchers from around the world, Transporters and Plant Osmotic Stress will be valuable to researchers, academicians, and scientists to enhance their knowledge and inspire further research in the field of transporters with respect to abiotic stress responses. It is complimented by its companion book titled Metal and Nutrient Transporters in Abiotic Stress.

Ion Channels, Part C, Volume 653 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Nonsense suppression in ion channels, Engineering Ion Channels Using Protein Trans-splicing, Probing Ion Channel Neighborhoods Using APEX, STX based probes for NaVs, ANAP: a versatile, fluorescent probe of ion channel gating and regulation, High Throughput Screens for Small Molecule Ion Channel Modulators, Using toxins to study ion channels, Re/de-constructing ubiquitin regulation of ion channels, Tethered Peptide Toxins for Ion Channels, Voltage-Sensing Phosphatase Molecular Engineering, and more. Additional chapters cover Engineering excitable cells, Stretch and Poke Stimulation of Mechanically-Activated Ion Channels, Optical Control of STIM Channels, High Throughput Electrophysiological Evaluation of Mutant Ion Channels, Evaluating BEST1 Mutations in RPE Stem Cells, Long Read Transcript Profiling of Ion Channel Splice Variants, Permeation of Connexin Channels, Ratiometric pH indicator for melanosomes and lysosomes, and Ion channels in the epithelial cells of the choroid plexus.

Advances in Microbial Physiology, Volume 78, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. This updated release contains the latest information in the field, with comprehensive chapters covering Microbubble Intensification of Bioprocessing, Bacterial cellulose: biosynthesis, production, and applications, Microbial energy management - a product of three broad tradeoffs, and more.

Ion Channels Part B, Volume 652 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including NMDAR, Pannexin, and CALHM, Making NaV1.4 and NaV1.7, TRPVs, Purification native nAChRs, GABAR Radu Aricescu, TRPV5/2, NaV1.5, KATP, TRPA1, TREK-1, SARS-CoV-2 3a ion channel, Ion channel conformational dynamics by encoded unnatural amino acid, Fluorescence lifetime measurement of absolute membrane potential, Fluorescent Toxins as Activity Sensors, FRET Analyses of Ion Channel Protein-Protein Interactions, Control of Ion Channel Gating with Photo-Switchable Tweezers, and Counting Subunits in Kv Channel Complexes.

Ion Channels Part A, Volume 651 in the Methods in Enzymology series, highlights new advances in the field with this new volume presenting interesting chapters on a variety of new developments on the topic. Each chapter is written by an international board of authors.

Advances in Clinical Chemistry, Volume 102, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the most up-to-date technologies related to the field of clinical chemistry. Chapters in this new release cover Advances in immunosensor technology, Extracellular Vesicles: Roles and Applications in Drug-Induced Liver Injury, Oxidative stress biomarkers in the preterm infant, Translational biomarkers in the era of precision medicine, Metabolomics applications in coronary artery disease personalized medicine, Quantitative EEG biomarkers for epilepsy and their relation to chemical biomarkers.

Proteomics and Systems Biology, Volume 127 in the Advances in Protein Chemistry and Structural Biology series, outlines current proteomic methodologies and discuss the challenges in future applications of systems biology in a number of biomedical/bioscience subjects. In last few decades, advances in genomics, proteomics, metabolomics, glycomics, venomics, etc., have produced vast large-scale datasets that need to be analyzed with a single main objective of understanding biological systems as a whole. Such understanding will allow us to predict and characterize the dynamic properties of biological systems.

Metal and Nutrient Transporters in Abiotic Stress focuses on the different forms of environmental stress related to heavy metal, metalloid and nutrient deficiency that have the potential to inflict major damages to crop plants, leading to a massive decrease in crop yield and productivity. The book presents the current state of knowledge of the biochemical and molecular regulation of several classes of membrane transporters related to the uptake of metals/metalloids and nutrient elements during different stresses and their probable mechanisms of operation in plant stress tolerance. Metal and Nutrient Transporters in Abiotic Stress provides a comprehensive discussion that will help in mitigating multiple forms of stresses utilizing transporter proteins. Edited by leading experts and written by a global team of knowledgeable contributors, this book will further stimulate research in the field of transporter proteins and will foster further interests for researchers, academicians and scientists worldwide. It is complimented by its companion book titled Transporters and Plant Osmotic Stress.

Reprogramming the Genome: Applications of CRISPR-Cas in Non-mammalian Systems Part B, represents the collation of chapters written by eminent scientists worldwide. CRISPR-Cas9 system is an RNA-mediated immune system of bacteria and archaea that protects from bacteriophage infections. It is one of the revolutionized technologies to uplift biology to the next stages. It is a simple, rapid, precise, and cost-effective tool for genome editing and regulation of a wide range of organisms. It has gained scientific and public attention worldwide. This volume mainly covers insect cell line, protozoans, zebrafish, drosophila, CRISPRi, patents as well as technology transfer, and many more. This book is a key source of information available in a single volume. This book will be useful for not only beginners in genome engineering, but also students, researchers, scientists, policymakers, and stakeholders interested in harnessing the potential of reprogramming of the genomes in several areas.

Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. A vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target this cell death process. These two thematic volumes 125 and 126 of the Advances in Protein Chemistry and Structural Biology focus on apoptotic responses in numerous conditions - from bacterial and parasite infections to pathological states such as oxidative stress, pulmonary hypertension, different cancer types, etc. Finally, therapeutic strategies for targeting apoptosis are also discussed.