This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English.

Due to various special physiological features and a genome that greatly differs in structure, gene content and organization from other yeasts, Y. lipolytica is widely used as a host system. With its characteristics, such as the ability to grow on lipids or grease, to accumulate oil and the high capacity for secretion of proteases and lipases, the yeast is of great interest for biotechnological applications. The main topics covered in this Microbiology Monograph are: expression and secretion of heterologous proteins; acid and alkaline extracellular proteases; genetics, production, biochemical characterization and biotechnological application of lipases; production and secretion of several organic acids and flagrances; as well as the functional expression of P450 systems and its use in steroid biotransformation.

The development of modern biotechnology has varied considerably from country to country. Typically, there are wide technology gaps between developing and industrialised countries and considerable differences in investment and regulatory systems, often creating a need for policy intervention. This innovative book examines the development and evolution of biotechnology in industrialised and developing countries. The author first explores efforts made by policymakers and the leaders in the field to reduce technology gaps, and analyses the development of financial mechanisms and regulatory frameworks to hasten the adoption and diffusion of biotechnology. The second section looks at the relationship between biotechnology and its resource base, biological diversity. The author emphasizes the interdependency between biodiversity and biological R&D in an attempt to simplify the debate on the conservation of biological diversity. The last section focuses on the potential positive and negative impacts of biotechnology and its contribution towards sustaining biodiversity. The Emergence and Growth of Biotechnology will be of great interest to undergraduate and postgraduate economics students interested in the economics of technology, economic development and biotechnology and environmental conservation.

Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation.

Encompasses a variety of different approaches, methodologies and disciplines.

Split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation.

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences.
This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry.
A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry.
Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actionsManufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processesCovers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries

This book highlights the advances in essential oil research, from the plant physiology perspective to large-scale production, including bioanalytical methods and industrial applications. The book is divided into 4 sections. The first one is focused on essential oil composition and why plants produce these compounds that have been used by humans since ancient times. Part 2 presents an update on the use of essential oils in various areas, including food and pharma industries as well as agriculture. In part 3 readers will find new trends in bioanalytical methods. Lastly, part 4 presents a number of approaches to increase essential oil production, such as in vitro and hairy root culture, metabolic engineering and biotechnology. Altogether, this volume offers a comprehensive look at what researchers have been doing over the last years to better understand these compounds and how to explore them for the benefit of the society.

Commercially, D-xylitol is produced by chemical reactions that are tailored to the requirements of various sectors. However, due to the rising interest in sustainable development and ecologically benign practices, microbial transformation processes are generally preferred over the conventional chemical conversion process. The former have multiple advantages, including less chemical load on the environment, higher efficiency, and the ability to dilute multiple downstream transformation attempts while maintaining product yield and recovery.

This book aims to disseminate the most current advances in the biotechnological production of D-xylitol and its applications in medical and health care. It is a unique collection of 15 book chapters split into 5 sections and written by experts in their respective fields, who present critical insights into several topics, review current research, and discuss future progress in this area. This book also provides essential information on hemicellulose hydrolysis to recover D-xylose, detoxification of hemicellulose hydrolysates, and improved fermentation methods for increased D-xylitol production. The highlights of strain improvement to increase the D-xylitol titers and downstream recovery of D-xylitol are also discussed in several sections. The current applications of D-xylitol in medical and health care have been used to justify the cost incurred for setting up the demonstration plant for D-xylitol production in the market. Apart from researchers and post-graduate students in the field of microbial biotechnology, this book will assist those in the business community who deal with the economic analysis of bio-based products and their marketing.

MATLAB(r) in bioscience and biotechnology presents an introductory Matlab course oriented towards various collaborative areas of biotechnology and bioscience. It concentrates on Matlab fundamentals and gives examples of its application to a wide range of current bioengineering problems in computational biology, molecular biology, bio-kinetics, biomedicine, bioinformatics, and biotechnology. In the last decade Matlab has been presented to students as the first computer program they learn. Consequently, many non-programmer students, engineers and scientists have come to regard it as user-friendly and highly convenient in solving their specific problems. Numerous books are available on programming in Matlab for engineers in general, irrespective of their specialization, or for those specializing in some specific area, but none have been designed especially for such a wide, interdisciplinary, and topical area as bioengineering. Thus, in this book, Matlab is presented with examples and applications to various school-level and advanced bioengineering problems - from growing populations of microorganisms and population dynamics, reaction kinetics and reagent concentrations, predator-prey models, mass-transfer and flow problems, to sequence analysis and sequence statistics.
This is the first book intended as a manual introducing biologists and other biotechnology engineers to work with MatlabIt is suitable for beginners and inexperienced users; however, applications of Matlab to advanced problems such as the Monte Carlo method, curve fitting, and reliable machine diagnostics make the book relevant to university teachers as wellThe book is different in that it assumes a modest mathematical background for the reader and introduces the mathematical or technical concepts with a somewhat traditional approach; Matlab is then used as a tool for subsequent computer solution

The book focuses on the principles and practices of tropical maize improvement with special emphasis on early and extra-early maize to feed the increasing population in Sub-Saharan Africa. It highlights the similarities and differences between results obtained in temperate regions of the world and WCA in terms of corroboration or refutation of genetic principles and theory of maize breeding. The book is expected to be of great interest to maize breeders, advanced undergraduates, graduate students, professors and research scientists in the national and international research institutes all over the world, particularly Sub-Saharan Africa. It will also serve as a useful reference for agricultural extension and technology transfer systems, Non-governmental Organizations (NGOs) and Community-Based Organizations (CBOs), seed companies and community-based seed enterprises, policy makers, and all those who are interested in generating wealth from agriculture and alleviating hunger and poverty in Sub-Saharan Africa.

Past, Present, and Future Industrial Biotechnology in China, by Zhenjiang Li, Xiaojun Ji, Suli Kan, Hongqun Qiao, Min Jiang, Dingqiang Lu, Jun Wang, He Huang, Honghua Jia, Pingkai Ouyuang, and Hanjie Ying.- Organic Chemicals from Bioprocesses in China, by Jin Huang, Lei Huang, Jianping Lin, Zhinan Xu, and Peilin Cen.- Biofuels in China, by Tianwei Tan, Jianliang Yu, Jike Lu, and Tao Zhang.- Bioreactors and Bioseparation, by Siliang Zhang, Xuejun Cao, Ju Chu, Jiangchao Qian, and Yingping Zhuang.- Environmental Biotechnology in China, by Shuang Jiang Liu , Lei Liu , Muhammad Tausif Chaudhry , Lei Wang , Ying Guang Chen , Qi Zhou , He Liu , and Jian Chen.- Traditional Chinese Biotechnology, by Yan Xu , Dong Wang , Wen Lai Fan , Xiao Qing Mu, and Jian Chen.- Modern Biotechnology in China, by Qing-Zhao Wang and Xue-Ming Zhao.

This volume of "Advances in Chemical Engineering "presents the latest developments in microsystems and devices for biochemical processes.
* Updates and informs the reader on the latest research findings using original reviews
* Written by leading industry experts and scholars
* Reviews and analyzes developments in the field

The book provides the most up-to-date information available on various biotechnological processes useful in the pulp and paper industry. The first edition was published in 2011, covering a specific biotechnological process or technique, discussing the advantages, limitations, and prospects of the most important and popular processes used in the industry. Many new developments have taken place in the last five years, warranting a second edition on this topic. The new edition contains about 35% new material covering topics in Laccase application in fibreboard; biotechnology in forestry; pectinases in papermaking; stickies control with pectinase; products from hemicelluloses; value added products from biorefinery lignin; use of enzymes in mechanical pulping.

This two-volume book is a valuable resource to students, researchers, scientists, commercial producers, consultants and policymakers interested in agriculture or plant sciences particularly in date palm biotechnology. Date Palm Biotechnology Protocols, Volume 1: Tissue Culture and Applications is comprised of 27 chapters covering adventitious organogenesis, somatic embryogenesis, contamination, hyperhydricity, acclimatization, cell suspension, protoplast and bioreactors, genetic transformation secondary metabolites, and abiotic stress. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Date Palm Biotechnology Protocols, Volume 1: Tissue Culture and Applications aims to supplement the previous volume and to provide precise stepwise protocols in the field of date palm biotechnology.

"Morphology Genetic Materials Templated from Nature Species" provides a comprehensive and up-to-date coverage of research on bio-inspired functional materials including materials science and engineering aspects of the fabrication, properties, and applications. The book discusses bio-inspired strategies integrating biotemplate, biomineralization, and biomimesis in nature, which are adopted to fabricate functional materials with hierarchical bio-architectures and interrelated outstanding performances, as well as valuable applications in photoelectricity, photonics, photocatalysis, chemical detection, bio-imaging, and photoelectron transfer components/devices.

The book is intended for researchers and graduate students in the fields of materials science, chemistry, nanotechnology, semiconductor, biotechnology, environmental engineering, etc.

Prof. Dr. Di Zhang is currently a professor at the School of Materials Science and Engineering, Shanghai Jiao Tong University, and the director of the State Key Laboratory of Metal Matrix Composites, China.

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Bacterial infections cause substantial morbidity and mortality in cancer patients. These infections always remained enigmatic due to initial reluctance of cancer researchers in understanding their etiologic potential. Etiological association of bacteria with cancer gained credibility after discovery of carcinogenic potential of Helicobacter pylori. Moreover, other suspected associations including Salmonella typhi and gallbladder cancer, Streptococcus bovis and colon cancer, Chlamydia psittaci and ocular adnexal lymphoma and Chlamydia pneumoniae with lung cancer, etc. are looking for a legitimate appraisal to unravel their etiologic potential without prejudice. In contrary, bacteria also show protective role in certain types of cancer. Certain agents derived from bacteria are successfully in practice for the management of cancer. The integrate association of bacteria and cancer is evident in both positive and negative aspects. The role of bacteria in cancer etiology and treatment is vigorously studied since last few years. Present book tries to provide current status of research undergoing in above direction, with the glimpses of future possibility for using microbiological knowledge in the management of this deadly killer. This book will interest specialists dealing with cancer associated infectious complications, researchers working in the field of cancer biology, teachers and scientists in the field of microbiology, biotechnology, medicine and oncology. The unique coverage of bacteriology and cancer association in both positive and negative way can usher into development of novel thrust area for microbiology students and experts.

The food, feed, ?ber, and fuel needs of the changing world pose the challenge of doubling or tripling of world food, feed, and ?ber production by the year 2050 to meet the needs of a 11 billion global population. In addition, the dramatic changes in food prices in the recent years further warrant that production and productivity need to be enhanced to ensure adequate supplies. Biotechnology can make a signi?cant contribution to this effort as demonstrated by cotton and other crops; the new advances in biotechnology have made it possible to develop plants that contain genes that were not possible to be developed by sexual means. Cotton has been a leader in the use of biotechnology. With the introduction of Bt cotton, followed by stacked cotton products (insect and herbicide tolerance) and extensive use of molecular breeding tools, cotton cultivation has been much improved. The contributions in this book illustrate the scienti?c advances that are going on in cotton and the impact they continue to deliver for all cotton growers. Twelve percent of the global cotton area is now under biotech products at 15. 5 million ha. The primary bene?ts from using genetically engineered cotton include reduced insecticide use, lower production costs, improved yields, lower farming risks, and increased opportunities to grow cotton in areas of severe pest infestation.

One of the most pressing tasks in biotechnology today is to unlock the function of each of the thousands of new genes identified every day. Scientists do this by analyzing and interpreting proteins, which are considered the task force of a gene. This single source reference covers all aspects of proteins, explaining fundamentals, synthesizing the latest literature, and demonstrating the most important bioinformatics tools available today for protein analysis, interpretation and prediction. Students and researchers of biotechnology, bioinformatics, proteomics, protein engineering, biophysics, computational biology, molecular modeling, and drug design will find this a ready reference for staying current and productive in this fast evolving interdisciplinary field.

Explains all aspects of proteins including sequence and structure analysis, prediction of protein structures, protein folding, protein stability, and protein interactions

Teaches readers how to analyze their own datasets using available online databases, software tools, and web servers, which are listed and updated on the book s web companion page.

Presents a cohesive and accessible overview of the field, using illustrations to explain key concepts and detailed exercises for students."

Materials from renewable resources are receiving increased attention, as leading industries and manufacturers attempt to replace declining petrochemical-based feedstocks with products derived from natural biomass, such as cereal straws. Cereal straws are expected to play an important role in the shift toward a sustainable economy, and a basic knowledge of the composition and structure of cereal straw is the key to using it wisely. Cereal Straw as a Resource for Sustainable Biomaterials and Biofuels: Chemistry, Extractives, Lignins, Hemicelluloses and Cellulose provides an introduction to straw chemistry. Topics discussed include the structure, ultrastructure, and chemical composition of straw; the structure and isolation of extractives from the straw; the three main components of straw: cellulose, hemicelluloses, and lignins; and chemical modifications of straw for industrial applications. This book will be helpful to scientists interested in the areas of natural resource management, environmental chemistry, plant chemistry, material science, polysaccharide chemistry, and lignin chemistry. It will also be of interest to academic and industrial scientists/researchers interested in novel applications of agricultural residues for industrial and/or recycling technologies.

Sustainable Biotechnology; Sources of Renewable Energy draws on the vast body of knowledge about renewable resources for biofuel research, with the aim to bridge the technology gap and focus on critical aspects of lignocellulosic biomolecules and the respective mechanisms regulating their bioconversion to liquid fuels and other value-added products. This book is a collection of outstanding research reports and reviews elucidating several broad-ranging areas of progress and challenges in the utilization of sustainable resources of renewable energy, especially in biofuels.