Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It illustrates the benefit of the principles of geriatrics in the management of cancer in the older individual.

This volume provides a frame of reference for practicioners of any specialties involved in the management of older patients and for oncologists involved in the management of cancer of older individuals. It is a source for basic and clinical scientists exploring the interactions and emerging information of cancer and aging.

The aim of this book is to present current views about physical activity and the benefits of physical activity in preventing and ameliorating various health conditions that are of worldwide concern. This book was developed as a compilation of the accomplishments of the five-year Global COE (Center of Excellence) "Sport Sciences for the Promotion of Active Life" Program at the Faculty of Sport Sciences of Waseda University, Saitama, Japan. The first part establishes the research methodology and discusses the current status of physical activity. Topics covered include the prevalence of physical inactivity and highly sedentary behavior in different populations as well as strategies that can be adopted to promote physical activity. The second part focuses on the physiological effects of physical activity. Topics covered include physiological responses to exercise by the autonomic nervous system, the endocrine system, vascular functioning, postprandial blood glucose control, and inflammatory processes. The relationship between exercise and appetite is discussed, as is the influence of exercise on food intake and weight regulation. Additionally, the influence of exercise on protein regulation and posttranslational modifications is introduced. The final part discusses the role of physical activity in preventing lifestyle-related health issues and improving the quality of life, especially for the elderly. The contents should be of interest to anyone who is concerned with the human physiologic response to exercise and the promotion of healthy lifestyles, including sports and exercise science researchers as well as those involved with medicine, public health, physiology, nutrition, and elder care.

Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of great importance to all mankind. Drugs are however powerful and must be handled appropriately. This is especially important for elderly patients. Drug-related problem is not a major subject in most university programmes in medicine or pharmacy. When there is no speci c course, there is often no book covering the topic. In our view, as teachers at various university courses, there has been a shortage of literature that re ects the most important aspects of drug-related problems in the elderly. Medical practitioners, nurses and pharmacists, need to have this knowledge to be able to serve their patients in the best way. This book covers most aspects of drug-related problems in the elderly. With b- ter knowledge of drug-related dif culties and risks we hope that elderly will have fewer drug-related problems and bene t more from their pharmacotherapy.

It is with great pride that the Psychologists in Long Term Care (PLTC) have sponsored The Professional Educational Long-Term Care Training Manual, and now its second iteration, Geropsychology and Long Term Care: A Practitioner's Guide. Education of psychologists working in long-term care settings is consistent with PLTC's mission to assure the provision of high-quality psychological services for a neglected sector of the population, i.e., residents in nursing homes and assisted-living communities. To this end, direct training of generalist psychologists in the nuances of psychological care delivery in long-term care settings has been a major priority. It is a tribute to the accelerating nature of research in long-term care settings that a revision is now necessary. After all, the Professional Educational Training Manual's initial publication date was only in 2001. However, in the intervening years, much progress has been made in addressing assessment and intervention strategies tailored to the needs of this frail but quite diverse population. It is so gratifying to be able to say that there is now a corpus of scientific knowledge to guide long-term care service delivery in long-term care settings.

For caregivers of deeply forgetful people: a book that combines new ethics guidelines with an innovative program on how to communicate and connect with people with Alzheimer's. How do we approach a "deeply forgetful" loved one so as to notice and affirm their continuing self-identity? For three decades, Stephen G. Post has worked around the world encouraging caregivers to become more aware of-and find renewed hope in-surprising expressions of selfhood despite the challenges of cognitive decline. In this book, Post offers new perspectives on the worth and dignity of people with Alzheimer's and related disorders despite the negative influence of "hypercognitive" values that place an ethically unacceptable emphasis on human dignity as based on linear rationality and strength of memory. This bias, Post argues, is responsible for the abusive exclusion of this population from our shared humanity. With vignettes and narratives, he argues for a deeper dignity grounded in consciousness, emotional presence, creativity, interdependence, music, and a self that is not "gone" but "differently abled." Post covers key practical topics such as: * understanding the experience of dementia * noticing subtle expressions of continuing selfhood, including "paradoxical lucidity" * perspectives on ethical quandaries from diagnosis to terminal care and everything in between, as gleaned from the voices of caregivers * how to communicate optimally and use language effectively * the value of art, poetry, symbols, personalized music, and nature in revealing self-identity * the value of trained "dementia companion" dogs At a time when medical advances to cure these conditions are still out of reach and the most recent drugs have shown limited effectiveness, Post argues that focusing discussion and resources on the relational dignity of these individuals and the respite needs of their caregivers is vital. Grounding ethics on the equal worth of all conscious human beings, he provides a cautionary perspective on preemptive assisted suicide based on cases that he has witnessed. He affirms vulnerability and interdependence as the core of the human condition and celebrates caregivers as advocates seeking social and economic justice in an American system where they and their loved ones receive only leftover scraps. Racially inclusive and grounded in diversity, Dignity for Deeply Forgetful People also includes a workshop appendix focused on communication and connection, "A Caregiver Resilience Program," by Rev. Dr. Jade C. Angelica.

Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed."

Assisting someone with Alzheimer s disease or another illness that causes dementia is incredibly demanding and stressful for the family. Like many disabling conditions, Alzheimer s disease leads to difficulty or inability to carry out common activities of daily life, and so family members take over a variety of tasks ranging from managing the person s finances to helping with intimate activities such as bathing and dressing.

Key coverage in "Caregiving for Alzheimer s Disease and Related Disorders" includes:

Early diagnosis and family dynamics
Emotional needs of caregivers
Developmentally appropriate long-term care for people with Alzheimer s
Family caregivers as members of the Alzheimer s treatment Team
Legal and ethical issues for caregivers
Faith and spirituality
The economics of caring for individuals with Alzheimer s disease
Cultural, racial, ethnic, and socioeconomic issues of minority caregivers
Advances in Alzheimer s disease research

"Caregiving for Alzheimer s Disease and Related Disorders" offers a wealth of insights and ideas for researchers, practitioners, and graduate students across the caregiving fields, including psychology, social work, public health, geriatrics and gerontology, and medicine as well as public and education policy makers."

There is a near-universal folk saying that everyone wishes to live a good long life, but no one wishes for old age. More contemporarily, the rock and roll band, Little Feat, sang, "You know that you're over the hill when your mind's making promises your body can't fill. " This book is about the good long life. It is a book about primary prevention strategies in the aging process; it is not about preventing that process. It is not about being old. Instead, it is about the things that individuals - and the helping professionals who provide them with counsel and assistance - can do to prevent the preventable problems of advancing age, and to better manage those changes in functioning that cannot be prevented. In short, it is about extending all our capacities to the fullest so that we can better keep all those promises that we make to ourselves and others. Aging is a life-long process. We focus here on the changes that are taking place in our selves and in our society as we age. In particular, we focus on what we can do to affect these changes by the choices we make and how we live. This book offers primary prevention strategies for mature and older adults, with the recognition that mature adulthood starts as soon as we are old enough to truly appreciate our active role in our own aging processes.

Although this monograph "Dependency o r interdependency in old age" is not the first publication o f the European Social Sciences Research C- mittee (ESSRC) o f the International Association o f Gerontology, I a m happy, as former chairman o f the Committee (1964-1975), to introduce this book to the readers, together with the present chairman. So far the activities o f the Committee have consisted o f co-operating in organizing the scientific programme o f the tri-annual congresses o f the International Association o f Gerontology (lAG), and in organizing sm- ler o r bigger symposia and colloquia for social gerontologists. Sometimes these meetings were mainly organized for European researchers only, sometimes several concurrent colloquia took place in which Americans and o t h e r non-Europeans participated. T h e Committee, the oldest o f the lAG, was established at a scientific meeting in 1954 at Sheffield (U. K. ) A f t e r that year colloquia were held in 1956 near Copenhagen 1 (Denmark), in 1957 at M e r a n o2 (Italy), in 1959 at Assisi (Italy), in 1960 a t Berkeley (Cal.

Gerontology is a multidisciplinary field, and this bibliography provides a multidisciplinary perspective on research on aging. The volume begins with an introductory chapter that desribes the range of interests to be found in gerontology, discusses the core concepts, and directs the reader to appropriate journals and handbooks. The bibliographic chapters that follow provide information on the most important works related to particular areas of gerontological research. Included are bibliographies on caregiving and health care, rituals related to death and dying, sleep disorders, Alzheimer's Disease, coronary disease, and the use of growth hormone in aging research. The chapters reflect social, anthropological, biological, ethical, and medical views. Each chapter begins with a brief essay on the latest trends in the field, and each entry includes a citation and a descriptive and evaluative annotation. Detailed indexes add to the usefulness of the volume.

This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.

This is the new and fully revised third edition of the well-received text that is the benchmark book in the field of nutrition and aging. The editors (specialists in geriatric nutrition, medical sociology, and clinical nutrition, respectively) and contributors (a panel of recognized academic nutritionists, geriatricians, clinicians, and other scientists) have added a number of new chapters and have thoroughly updated the widely acclaimed second edition. This third edition provides fresh perspectives and the latest scientific and clinical developments on the interaction of nutrition with age-associated disease and provides practical, evidence-based options to enhance this at-risk population's potential for optimal health and disease prevention. Chapters on a wide range of topics, such as the role of nutrition in physical and cognitive function, and coverage of an array of clinical conditions (obesity, diabetes, heart failure, cancer, kidney disease, osteoporosis), compliment chapters on food insecurity, anti-aging and nutritional supplements, making this third edition uniquely different from previous editions. Handbook of Clinical Nutrition and Aging, Third Edition, is a practical and comprehensive resource and an invaluable guide to nutritionists, physicians, nurses, social workers and others who provide health care for the ever-increasing aging population.

Distinguished physicians critically review the clinical consequences of the endocrinological changes that occur with aging-in both men and women-and examine the use of hormonal therapy to reduce them. Topics range from bone disease and water balance in all older people, to androgen deficiency in aging males, gynecomastia, and menopause. The authors also discuss Type II diabetes in persons over 65, emphasizing the cognitive benefits of good glycemia control, and the interaction of nutrition and metabolism, focusing on hypocholesterolemia, obesity, the anorexia of aging, trace elements, and vitamins. The aging of the sympathetic nervous system and its impact on hypertension in the elderly is also covered. Timely and authoritative, Endocrinology of Aging offers endocrinologists, geriatricians, and primary care physicians critical insight into the endocrine problems of our rapidly growing elderly population.

Late life is characterized by great diversity in memory and other cognitive functions. Although a substantial proportion of older adults suffer from Alzheimer's disease or another form of dementia, a majority retain a high level of cognitive skills throughout the life span. Identifying factors that sustain and enhance cognitive well-being is a growing area of original and translational research. In 2009, there are as many as 5.2 million Americans living with Alzheimer's disease, and that figure is expected to grow to as many as 16 million by 2050. One in six women and one in 10 men who live to be at least age 55 will develop Alzheimer's disease in their remaining lifetime. Approximately 10 million of the 78 million baby boomers who were alive in 2008 can expect to develop Alzheimer's disease. Seventy percent of people with Alzheimer's disease live at home, cared for by family and friends. In 2008, 9.8 million family members, friends, and neighbors provided unpaid care for someone with Alzheimer's disease or another form of dementia. The direct costs to Medicare and Medicaid for care of people with Alzheimer's disease amount to more than $148 billion annually (from Alzheimer's Association, 2008 Alzheimer's Disease Facts and Figures). This book will highlight the research foundations behind brain fitness interventions as well as showcase innovative community-based programs to maintain and promote mental fitness and intervene with adults with cognitive impairment. The emphasis is on illustrating the nuts and bolts of setting up and utilizing cognitive health programs in the community, not just the laboratory.

Leaders in neuropsychology, behavioral neurology, speech and language science, neuropsychiatry, and many other disciplines contribute to this volume, the first comprehensive review of knowledge in the field. They discuss a wide range of disorders, including areas of recent research - such as frontal lobe dementias and the neuropsychological aspects of late life depression - and clinical problems typically given insufficient consideration in other works, such as seizure disorder, head injury, and mental retardation. Normal aging is also covered in detail, and assessment procedures and clinical interventions are given thorough treatment. Other highlights include discussions of guardianship and caregiving personality and behavior, psychotic disorders, Alzheimer's, and head trauma.

The Owner's Manual for Your Eyes: The most comprehensive guide to taking care of vision. Winner of the National Health Information Award (Consumer Decision-Making Information) by the National Health Information Awards, American Book Fest Best Book Social Change and Current Events by the American Book Fest In The Eye Book, specialist Dr. Gary H. Cassel presents readers with trusted, evidence-based information they can rely on to protect vision and learn more about how to treat any eye problems that come up. This easy-to-understand volume takes a step-by-step approach, providing an overview of the eye's anatomy, a tour of healthy vision, and an explanation of what steps readers and health care providers should take to address vision issues. Drawing on years of clinical experience with patients, Cassel also looks at eye complications associated with common medical conditions (for example, diabetes) along with the best treatments for eye conditions, such as cataracts and glaucoma. Now in its second edition, this bestselling book continues to provide the interested reader, along with nurse practitioners, physician assistants, internists, and family doctors, with practical information about * eyeglass materials, contact lenses, and refractive surgeries (including LASIK) to improve vision * tips to spot and treat common eye irritations and infections, including conjunctivitis ("pink eye") * advice about when people should take care of an eye problem on their own and when they need to consult with an expert * what people (and their health care providers) can do about blurriness, dry eyes, eye strain, eye allergies, and floaters * how vision problems may be a sign of other health conditions, including thyroid problems and multiple sclerosis * which medications may affect vision * what people within and outside of the medical field need to know about macular degeneration and low vision Richly illustrated and engagingly written, this edition features special bonus material, including a chapter on cosmetics and the eye, FAQs ("Can cataracts grow back after cataract surgery?"; "Will I go blind from my glaucoma?"), and a handy symptom index that allows readers to research topics by the presentation of an eye problem. Useful for everyone, including general medical professionals who want to learn more about the health of the eyes, this up-to-date, in-depth, and authoritative book will serve as a users' manual for the eyes and help promote better vision for a brighter tomorrow.

In this book, leading authors in the field discuss the habitats of tomorrow. These habitats will be connected through autonomous and assistive systems, turning habitats into health resorts. This book discusses how assistance technologies enable a smooth transition from comfortable health support to medical or nursing care. The contributions have been chosen and invited at the 9th AAL congress, Frankfurt.

Clinical Manual of Geriatric Psychiatry provides the most current information on psychiatric diagnoses seen in older patients in a concise format. Each chapter is broken into easily understandable, increasingly focused sections, and contains an extensive array of tables, references, and suggested readings. Chapters include clinically relevant information and evidence-based treatments for a wide range of topics and disorders: * The psychiatric interview of older adults, including history, family assessment, mental status examination, rating scales and standardized interviews, and effective communication techniques.* Psychopharmacology, including information on antidepressants, psychostimulants, antipsychotic medications, mood stabilizers, anxiolytics and sedative-hypnotics, and cognitive enhancers.* Diagnosis and treatment of delirium, dementia, mood disorders, schizophrenia, anxiety disorders, sleep disorders, and substance use disorders, including coverage of definition, epidemiology, clinical features, risk factors, diagnosis and differential diagnosis, prevention and management, and treatment guidelines.* Individual and group psychotherapy strategies, including individual and group-based cognitive-behavioral therapies, interpersonal psychotherapies, relaxation training, cognitive stimulation therapy, and behavioral therapies.* Clinical psychiatry in the nursing home, with a focus on cognitive disorders and behavioral disturbances, depression, treatment progress in this setting, and relevant federal regulations. Written by experts in geriatric psychiatry, this clinical manual provides a much-needed "field guide" for the care of nursing home patients and older adults. Busy clinicians, as well as researchers, residents, fellows, clinical psychologists, and social workers, will find this compact volume to be of the utmost value, as will anyone seeking to update their knowledge of geriatric psychiatry.

The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014), will focus on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments and will provide an international forum for the latest scientific discoveries, medical practices and care initiatives. Advances information technologies will be discussed along with their implications for various research, implementation and policy concerns. In addition, the conference will address European and global issues in the funding of long-term care and medico-social policies regarding elderly people. GeNeDis 2014 takes place in Corfu, Greece, 10-13 April 2014. This volume focuses on the sessions that address neurodegenerative diseases.

The preparation of Aging, Immunity, and Infection has been a "labor of labor. " When we began, there existed a huge literature-but manage able, we thought, given our years of experience in the area often referred to as immunogerontology. However, in the time that we have been at work, the new relevant literature has increased at a prodigious rate. The more we read and tried to assimilate, the farther we fell behind. In order to have any hope of completing a book on this rapidly evolving topic, we have been forced to become increasingly selective in covering new and re cent publications. We dare to hope that many read ers will find the book useful and only a few will dweIl on the inevitable inadequacies. We consider the book a work in progress, and welcome suggestions for future editions. Five chapters cover several aspects of infection and the decline of immunity with age. The first chapter "Human Aging: Present and Future," is devoted to demographics and theories of senescence. Chap ter 2 outlines the gradual breakdown of resistance to infection in the aged individual. Chapters 3 and 4 cover changes in innate and acquired immunity. The final chapter, "Nutrition, Longevity, and Integrity of the Immune System," discusses such provocative ideas as life-span exten sion and nutritional intervention for the delay of immunosenescence."

That geriatric cardiology has become a science and clinical discipline in its own rights is beyond dispute. Most cardiac disorders present with different symptoms and signs, require a different diagnostic and therapeutic approach, and also have a different prognosis in the elderly as compared to younger patients. Cardiovascular Disease in the Elderly provides a comprehensive, up-to-date guide to the physician, representing a pioneering work in this increasingly complex area. For this third edition most of the chapters have been completely rewritten, some by different authors. Four new chapters have been added, dealing with cardiac transplantation, invasive cardiovascular procedures, dietary considerations and ethical considerations. It cannot be denied that invasive procedures and transplantation are highly controversial in this area, and the ethical dilemmas involved are ably discussed by Dr Davis and associates. All chapters are supplied with a thorough list of references, making this third edition of Cardiovascular Disease in the Elderly the most thorough, concise guide for the practicing physician.

The National Institute on Aging (NIA) has historically been concerned with the protection of human subjects. In July 1977, the NIA sponsored a meeting to update and supplement guide lines for protecting those participating in Federal research pro jects. Although the basic guidelines had been in effect since 1966, it had been neglected to include the elderly as a vulnerable population. In November 1981, the NIA organized a conference on the ethical and legal issues related to informed consent in senile dementia cases. The present volume offers the latest and best thinking on Alzheimer's Dementia to have emerged from the dialog that was first embarked upon at the NIA meeting. Indeed, the issues and concerns it treats now seem even more relevant than they appeared historically because of the vastly greater awareness in the community of the entire spectrum of problems Alzheimer's disease confronts us all with. Our interest and concern is both humanitarian and self serving. Clearly older people must be protected from in appropriate research and careful attention must be paid to the circumstances under which research is conducted on those older persons who have given anything less than full consent. It is equally necessary, however, for the research enterprise to be protected so that today's elderly and those of the future can benefit from the fruits of research."