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Books > Medicine > Clinical & internal medicine > Geriatric medicine

Empowering Frail Elderly People - Opportunities and Impediments in Housing, Health, and Support Service Delivery (Hardcover,... Empowering Frail Elderly People - Opportunities and Impediments in Housing, Health, and Support Service Delivery (Hardcover, New)
Duncan P. Boldy, Leonard F. Heumann, Mary McCall
R2,545 Discovery Miles 25 450 Ships in 10 - 15 working days

This book provides a unique analysis of provider-, environment-, client-, and societal-based obstacles to the empowerment of frail elderly persons in a philosophical framework of social values, as well as an applied framework wherein a variety of international case studies by a distinguished board of contributors provide concrete examples of the feasibility of achieving real empowerment. Empowerment means different things to different people in the context of housing, health, and social service delivery. This book analyzes the various definitions of the concept and practice of the empowerment of frail older persons and then discusses the definitions in a philosophical framework of social values regarding aging and the older person.

Each chapter demonstrates the feasibility of achieving increased empowerment of older persons, even those with severe physical or mental disability. True empowerment of older persons in every country requires time, energy, money, and commitment to the goal. This book will be of interest to academic as well as professional audiences in areas of Gerontology, Psychology, Sociology, and Family Studies. Caregivers and policymakers will also find this analysis useful.

The Science and Practice of Gerontology - A Multidisciplinary Guide (Hardcover, New): Nancy Osgood, Ann H. I. Sontz The Science and Practice of Gerontology - A Multidisciplinary Guide (Hardcover, New)
Nancy Osgood, Ann H. I. Sontz
R1,889 Discovery Miles 18 890 Ships in 10 - 15 working days

This definitive guide encompasses past, present, and future issues of theory, research, and practice in areas of interest and specialization in aging, and represents current trends of thought on gerontology, the science of and associated practices with the elderly. This volume is a collection of articles dealing with the psychological, social, and cultural domains affecting older people and contains general biomedical understandings and practical/clinical applications. The contributors broadly outline some of the most relevant academic issues, including cross-cultural perspectives on age and aging; past and future trends in life expectancy with underlying explanations; innovations and advances in research design and methodology in the study of the aging process and the effects of age as a variable; and past and current theoretical perspectives on the psychology and sociology of aging. Some pertinent concerns for practitioners and clinicians are addressed, such as successful counseling therapies with older adults and changes in social work and rehabilitation practice with the elderly. The thought-provoking chapters provide a wide-sweeping, multidisciplinary review of a rapidly expanding field of interest and represent a definite desire among the contributors to evolve a theoretical apparatus and a related, applied arena of endeavor.

This important work on a significant and timely issue of concern will broaden our understanding and awareness of the rising number of positive efforts within gerontological studies now being derived from diverse disciplinary roots. The reader will find articles on subjects of particular interest, such as the Biology of Aging, the Psychology of Adult Development and Aging, Rehabilitation of the Elderly, and Social Work and Aging. An extraordinarily detailed reference, this work will be a valuable resource for gerontologists, social workers, psychologists, and doctors specializing in geriatrics.

Geriatrics Handbook (Hardcover): Roger Simpson Geriatrics Handbook (Hardcover)
Roger Simpson
R2,405 R2,196 Discovery Miles 21 960 Save R209 (9%) Ships in 18 - 22 working days
Handbook of Aging and Mental Health - An Integrative Approach (Hardcover, 1998 ed.): Jacob Lomranz Handbook of Aging and Mental Health - An Integrative Approach (Hardcover, 1998 ed.)
Jacob Lomranz
R7,136 Discovery Miles 71 360 Ships in 18 - 22 working days

De cibo quod superest nobis sufficit; oportet gratias agere. Some elders have accepted this proposition, although seldom with enthu- siasm. Gerontologists also have been burdened with the adage: "Leftovers are good enough for us, and we should be grateful for them." I remember how a clerk tried to palm off astale and cheap cigar to her octogenarian customer. He knew better and carne away with a far superior smoke. The clerk fumed, "What does he need a good cigar for? Who is he to be particular!" In this and in many other ways, elders often have labored under the sociocultural expectation that they should be well content with whatever scraps and shmattes happen to come their way. Gerontologists can identify with this situation. The systematic study of aging and the aged was a new enterprise at the midpoint of this century, but the concepts and methods were pretty much limited to those already on hand. What biological and sociobehavioral scientists had been doing for years was simply extended to the newly annexed territory. This as not only a convenient but also a cost-effective strategy. Data accumulated more rapidly by remaining within familiar frarnes of reference and relying on farniliar designs and mea- sures. The new gerontologists soon harvested a promising crop of descriptive findings. Within a decade after the establishment of the Gerontological Society of America (1947), it was possible to discern the outlines of a valuable new field of knowledge.

Frailty in the Elderly - Understanding and Managing Complexity (Hardcover): Sara Palermo Frailty in the Elderly - Understanding and Managing Complexity (Hardcover)
Sara Palermo
R3,065 Discovery Miles 30 650 Ships in 18 - 22 working days
Legal Aspects of Health Care for the Elderly - An Annotated Bibliography (Hardcover, Annotated edition): Marshall Kapp Legal Aspects of Health Care for the Elderly - An Annotated Bibliography (Hardcover, Annotated edition)
Marshall Kapp
R1,210 Discovery Miles 12 100 Ships in 10 - 15 working days

Kapp's annotated list of 617 titles, in 13 sections, focuses on sources that discuss the `identifiable body of law concerned with personal and institutional relationships, implicated by the delivery of health care for the elderly.' This work is meant for health professionals, attorneys, researchers, educators, and advanced students. The succinct yet informative annotations cover references from January 1, 1980, to August 31, 1987. . . . Highly recommended. Choice Legal questions relating to health care for the elderly have grown increasingly numerous and complex. While these issues have been dealt with extensively by researchers and professional specialists, the literature has grown so vast in the past decade that it is difficult to keep abreast of legal developments. This bibliography is designed to assist practicing health, human services, and legal professionals as well as researchers, teachers, and students in identifying and evaluating information sources that will provide essential guidance on the legal implications of health care for the elderly. Organized in thirteen subject sections, the volume contains more than six-hundred annotated references dealing with institutional regulations and standards of care, disability determinations, decisionmaking for critically ill patients, involuntary commitment, advocacy services for the older health care consumer, and many other topics. Citations consist of books, book chapters, journal articles, and reports published from 1980 onwards. Entries are cross-referenced systematically, and author and subject indexes are provided. This important new reference will be an invaluable working tool for professionals and students who need to understand and deal with some of the most difficult issues in the field of modern health care.

The Eye Book - A Complete Guide to Eye Disorders and Health (Paperback, second edition): Gary H. Cassel The Eye Book - A Complete Guide to Eye Disorders and Health (Paperback, second edition)
Gary H. Cassel
R626 R580 Discovery Miles 5 800 Save R46 (7%) Ships in 18 - 22 working days

The Owner's Manual for Your Eyes: The most comprehensive guide to taking care of vision. Winner of the National Health Information Award (Consumer Decision-Making Information) by the National Health Information Awards, American Book Fest Best Book Social Change and Current Events by the American Book Fest In The Eye Book, specialist Dr. Gary H. Cassel presents readers with trusted, evidence-based information they can rely on to protect vision and learn more about how to treat any eye problems that come up. This easy-to-understand volume takes a step-by-step approach, providing an overview of the eye's anatomy, a tour of healthy vision, and an explanation of what steps readers and health care providers should take to address vision issues. Drawing on years of clinical experience with patients, Cassel also looks at eye complications associated with common medical conditions (for example, diabetes) along with the best treatments for eye conditions, such as cataracts and glaucoma. Now in its second edition, this bestselling book continues to provide the interested reader, along with nurse practitioners, physician assistants, internists, and family doctors, with practical information about * eyeglass materials, contact lenses, and refractive surgeries (including LASIK) to improve vision * tips to spot and treat common eye irritations and infections, including conjunctivitis ("pink eye") * advice about when people should take care of an eye problem on their own and when they need to consult with an expert * what people (and their health care providers) can do about blurriness, dry eyes, eye strain, eye allergies, and floaters * how vision problems may be a sign of other health conditions, including thyroid problems and multiple sclerosis * which medications may affect vision * what people within and outside of the medical field need to know about macular degeneration and low vision Richly illustrated and engagingly written, this edition features special bonus material, including a chapter on cosmetics and the eye, FAQs ("Can cataracts grow back after cataract surgery?"; "Will I go blind from my glaucoma?"), and a handy symptom index that allows readers to research topics by the presentation of an eye problem. Useful for everyone, including general medical professionals who want to learn more about the health of the eyes, this up-to-date, in-depth, and authoritative book will serve as a users' manual for the eyes and help promote better vision for a brighter tomorrow.

Advances in Geroscience (Hardcover, 1st ed. 2016): Felipe Sierra, Ronald Kohanski Advances in Geroscience (Hardcover, 1st ed. 2016)
Felipe Sierra, Ronald Kohanski
R4,134 Discovery Miles 41 340 Ships in 18 - 22 working days

This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or 'healthspan.' The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer's diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.

Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care (Hardcover): Jinglong Wu Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care (Hardcover)
Jinglong Wu
R5,138 Discovery Miles 51 380 Ships in 18 - 22 working days

The prominence of dementia within the global aging population has undergone an increase in recent years. To improve the living conditions of patients, researchers must place more emphasis on early detection methods. Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care provides a thorough overview of emerging research on various neuroscience methods for the early diagnosis of dementia and focuses on the improvement of healthcare delivery to patients. Highlighting relevant issues on health information systems, behavioral indicators, and treatment methods, this book is a pivotal reference source for health professionals, neuroscientists, upper-level students, practitioners, and researchers interested in the latest developments within the field of dementia treatment.

Neuroglia in the Aging Brain (Hardcover, 2002 ed.): Jean De Vellis Neuroglia in the Aging Brain (Hardcover, 2002 ed.)
Jean De Vellis
R5,297 Discovery Miles 52 970 Ships in 18 - 22 working days

A distinguished panel of internationally recognized neuroscientists comprehensively review the involvement of and changes in glial cells both during the normal aging process and in the major disorders of old age. Topics range from the cellular and molecular changes that occur with aging-especially aging-associated activation of astrocytes and microglia and its relation to neuronal injury and repair-to neuron-glia intercommunication. The contributors show how glial signals may be modulated by hormones, growth factors, neurotransmitters, intracellular metabolism, and intercellular exchanges, as well as by aging of the blood-brain barrier.

Assessing And Treating Late-life Depression: A Casebook And Resource Guide (Hardcover): Margaret Gatz, Michele Karel, Suzanne... Assessing And Treating Late-life Depression: A Casebook And Resource Guide (Hardcover)
Margaret Gatz, Michele Karel, Suzanne Ogland-Hand
R1,318 Discovery Miles 13 180 Ships in 18 - 22 working days

Not only is depression among the elderly treatable but, given its increase in incidence and a rapidly aging population, it is a critical issue for the mental-health and medical communities. The authors review the range of late-life depressive syndromes and the strategies for assessing and treating them, and illustrate the problems and principles with fourteen extended case studies-rare in the geropsychology literature and the core of the book. They also provide a guide to medications, screening tools, innovative models, and supplementary resources, invaluable tools for mental-health professionals and medical practitioners alike.

Functional Neurobiology of Aging (Hardcover): Patrick R. Hof, Charles V. Mobbs Functional Neurobiology of Aging (Hardcover)
Patrick R. Hof, Charles V. Mobbs
R5,480 Discovery Miles 54 800 Ships in 10 - 15 working days

Some well-known age-related neurological diseases include Parkinson's disease, Alzheimer's disease, deafness, and blindness. Even more common are the problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging continue to become more common, and conditions associated with aging need more attention by doctors and researchers. In 1991, patients over the age of 65 saw their doctors an average of eight times per year. Research funding is provided by the Neuroscience and Neuropsychology of Aging (NNA) Program, which is run by the National Institute on Aging. This book offers a comprehensive overview of all topics related to functional impairments which are related to the aging brain and nervous system. It is organized according to four general functions: movement, senses, memory, and neuroendocrine regulation. Written by the leading researchers in the field, this comprehensive work addresses both impairments associated with diseases and not associated with diseases, making it easier to understand the mechanisms involved. Functional Neurobiology of Aging is an important reference for professionals and students involved in aging research, as well as physicians who need to recognize and understand age-related impairments.
Key Features
* Organized by function, making it easy to find and understand the material
* Addresses impairments both associated with diseases and not associated with diseases
* Written by leading researchers in the field
* Most comprehensive source of information on the neurobiology of aging

Preventing Falls - A Defensive Approach (Paperback): J. Thomas Hutton, Jeffrey W. Elias, Jo Ann Shroyer, Zane Curry Preventing Falls - A Defensive Approach (Paperback)
J. Thomas Hutton, Jeffrey W. Elias, Jo Ann Shroyer, Zane Curry
R465 Discovery Miles 4 650 Ships in 18 - 22 working days

The risk of serious injury resulting from a fall increases with age as our eyesight, ability to react quickly, memory, and cognitive functions begin to decline. For the growing population of people over age 65, falls can lead to loss of dignity and independence, and they can cause serious injury or even death.

Preventing Falls is an essential guide for the elderly, caregivers, Parkinson's sufferers, and many others who face this health risk in their daily lives. As people age, knowing how to accommodate motor, sensory, and cognitive changes is important. While no single cause for a fall exists, the leading factors are environmental hazards, balance problems, muscle weakness, poor vision, and impaired judgment. Parkinson's patients as well as those with various neurological or muscular disorders are especially prone to falls because their motor skills are seriously compromised. This book addresses valuable skills and coping mechanisms as well as environmental changes and assistive devices that are needed to prevent falls.

Many elderly victims of a fall require the skilled care of a nursing home within a year of the incident, especially those elders who cannot care for themselves and whose family members are unable to provide adequate help. The editors place emphasis on "successful aging"-the ability to maintain mobility and remain independent. Preventing Falls is a handy guidebook for elders to decrease their risk of falls, develop personal confidence, and maintain their independence. This vital sourcebook is complemented with a valuable 60-minute videotape offering step-by-step instruction on the best methods for preventing falls.

Reviews of Physiology, Biochemistry and Pharmacology 139 (Hardcover, 1999 ed.): M.P. Blaustein, R. Greger, H. Grunicke, R.... Reviews of Physiology, Biochemistry and Pharmacology 139 (Hardcover, 1999 ed.)
M.P. Blaustein, R. Greger, H. Grunicke, R. Jahn, W.J. Lederer, …
R5,237 Discovery Miles 52 370 Ships in 18 - 22 working days

In this volume of Reviews of Physiology, Biochemistry and Pharmacology there a contributions by M.D. Swope, E. Lolis, F.Hofmann, L. Lacinova, N. Klugbauer, M. Hermann, P. Berger, S.S. Shen, J.S. Kim, M.E. Weksler, M. Hirsch-Kauffmann and M.Schweiger.

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease (Hardcover, 1st ed. 2016): Lori M. Buhlman Mitochondrial Mechanisms of Degeneration and Repair in Parkinson's Disease (Hardcover, 1st ed. 2016)
Lori M. Buhlman
R5,616 Discovery Miles 56 160 Ships in 18 - 22 working days

This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson's disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson's disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson's etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson's disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson's disease, efforts to postpone, prevent and "cure" onset mitochondrial aberrations and neurodegeneration associated with Parkinson's disease in various models are encouraging. While only about ten percent of Parkinson's patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson's disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.

The Aging Skeleton (Hardcover): Clifford J. Rosen, Julie Glowacki, John P. Bilezikian The Aging Skeleton (Hardcover)
Clifford J. Rosen, Julie Glowacki, John P. Bilezikian
R3,951 Discovery Miles 39 510 Ships in 10 - 15 working days

The Aging Skeleton is a comprehensive and timely book on all aspects of the skeleton as it ages, including basic mechanisms and pathways as well as pathobiology. Chapters cover general aspects and models of aging, determinants and maintenance of peak bone mass, mechanisms of age-related bone loss, quantifiable manifestations of age-related bone loss, fractures, and therapeutics.
Key Features
* Covers all aspects of the aging skeleton in one comprehensive volume
* Looks at the influence of genetics, nutrition, environment, hormones, and other factors on bone mass
* Provides a thorough discussion of fractures, one of the major consequences of the aging skeleton
* Reviews current therapeutic approaches and methods
* Written by internationally renowned authors and edited by leaders in the field
* Is the only book available on this subject

Care-Related Quality of Life in Old Age - Concepts, Models, and Empirical Findings (Hardcover, 2008 ed.): Marja Vaarama,... Care-Related Quality of Life in Old Age - Concepts, Models, and Empirical Findings (Hardcover, 2008 ed.)
Marja Vaarama, Richard Pieper, Andrew Sixsmith
R2,697 Discovery Miles 26 970 Ships in 18 - 22 working days

It 's a core issue at the heart of elder care: while best-practice data exist for long-term care, quality of life as a concept, measure and standard for care outcomes remains elusive. The result of an ambitious European research initiative, the Care Keys Project addresses quality of life issues among frail, care-dependent seniors, taking their social as well as health needs into account. This resulting volume explains the theory behind Care Keys, its methodology, empirical findings, and practical considerations in promoting effective, efficient elder care aimed at social and emotional well-being and including disabled and cognitively impaired patients.

Dementia Care (Paperback): Trevor Adams, Charlotte L. Clarke Dementia Care (Paperback)
Trevor Adams, Charlotte L. Clarke
R1,269 Discovery Miles 12 690 Ships in 10 - 15 working days

This book provides a comprehensive research-based source of material, which focuses on the important issue of dementia and family care. It critically examines how dementia is defined, diagnosed and "treated" and provides a new environmentally focused approach to this challenging and growing issue for nurses and other care givers.

Older People, Nursing & Mental Health (Paperback): Alan Crump, Jim Marr, Maria Scurfield, Stuart Darby Older People, Nursing & Mental Health (Paperback)
Alan Crump, Jim Marr, Maria Scurfield, Stuart Darby
R912 Discovery Miles 9 120 Ships in 10 - 15 working days

A much needed practical nursing text addressing the complex problems posed by the growing number of elderly people with mental health problems. The book can be used as an everyday companion for qualified nurses or for teaching health care assistants and students about practical interventions, therapeutic approaches and for developing knowledge and attitudes. Wider issues are considered, including the care continuum through acute to continuing care, and different care environments. * Practical advice for dealing with every-day problems * Examines common mental health problems in depth, to develop nurses' understanding of clients' needs * Positive approach, challenging stereotypical views and giving guidance for good care practices

Handbook of the Aging Brain (Hardcover): Eugenia Wang, D.Stephen Snyder Handbook of the Aging Brain (Hardcover)
Eugenia Wang, D.Stephen Snyder
R2,089 Discovery Miles 20 890 Ships in 10 - 15 working days

< B> Handbook of the Aging Brain< /B> brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.

Promoting Positive Practice in Nursing Older People - Perspectives on Quality of Life (Paperback): Sharon Pickering, Jeannette... Promoting Positive Practice in Nursing Older People - Perspectives on Quality of Life (Paperback)
Sharon Pickering, Jeannette Thompson
R1,006 Discovery Miles 10 060 Ships in 10 - 15 working days

Demographically, the care of older people is a growing area of concern. The growth in nursing care in this area has been tremendous both within and without the NHS. Nursing texts have tended to be limited to medical aspects of ill-health, but nursing older people as a specialty is developing a much more positive, holistic focus. This book provides a practice-based text concentrating on how nursing should focus on positive aspects of care and developing quality of life. Growing older is often regarded purely in negative terms and this has a profound influence on the practice of caring for older people. This innovative text focuses on promoting a positive approach to practice and the value of older people in our society. Unlike other books in this field, it avoids a medical approach and instead focuses on health, individuality and relationships in caring--the quality of life which should be the aim of care. Section 1--Values, Attitudes and Beliefs: cultural perspectives, choice and autonomy, risk management Section 2--Optimum Health: positive approaches to health, sexuality, spirituality, social networks Section 3: Therapeutic Interventions: communication, touch, sensory environments, relaxation Section 4: Future Issues: outcome measures, resource issues, policy dimensions. Drawing on a range of contributors from the fields of learning disabilities and mental health as well as adult health, the editors have recognised that many different disciplines can contribute to developing new partnerships in approaches to care. Practice-focused, the text features case studies and activities extensively to encourage readers to reflect on their own values and experiences and the experiences of older people. This practice-based text will inspire both students and practitioners working with older people to reflect upon their practice, think differently and discover new approaches to care.positive approach integrates theory and practice from different disciplines chapters included on innovative practical approaches to therapeutic communication including the use of touch and relaxationcolour plate section extensive use of case studies provides links to readers practiceuser-friendly text design includes reflection and discussion points

Aging Issues in Cardiology (Hardcover, 2004 ed.): Irene D. Turpie, George A. Heckman Aging Issues in Cardiology (Hardcover, 2004 ed.)
Irene D. Turpie, George A. Heckman
R2,772 Discovery Miles 27 720 Ships in 18 - 22 working days

Aging Issues in Cardiology provides an overview of the practical clinical areas involved in managing cardiovascular disease in the elderly. This volume will be useful to any physician managing the cardiovascular health of elderly individuals.
Topics covered include:

-Delirium in Elderly Cardiac Patients,
-Depression,
- Pharmacologic Issues,
- Primary Prevention,
- Syncope,
- Heart Failure,
- Coronary Revascularization.

Cellular Ageing and Replicative Senescence (Hardcover, 1st ed. 2016): Suresh I.S. Rattan, Leonard Hayflick Cellular Ageing and Replicative Senescence (Hardcover, 1st ed. 2016)
Suresh I.S. Rattan, Leonard Hayflick
R4,550 R3,479 Discovery Miles 34 790 Save R1,071 (24%) Ships in 10 - 15 working days

This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.

Calorie Restriction, Aging and Longevity (Hardcover, 2010 Ed.): Arthur V. Everitt, Suresh I.S. Rattan, David G. Couteur, Rafael... Calorie Restriction, Aging and Longevity (Hardcover, 2010 Ed.)
Arthur V. Everitt, Suresh I.S. Rattan, David G. Couteur, Rafael De Cabo
R5,195 Discovery Miles 51 950 Ships in 18 - 22 working days

Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life.

Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem?

Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Atlas of Intestinal Stomas (Hardcover): Victor W. Fazio, James M. Church, James S. Wu Atlas of Intestinal Stomas (Hardcover)
Victor W. Fazio, James M. Church, James S. Wu
R4,031 Discovery Miles 40 310 Ships in 10 - 15 working days

Designed to provide a highly visual reference for surgeons and other members of the patient management team, Atlas of Intestinal Stomas is based on the 1967 gold standard text, Turnbull and Weakly's Atlas of Intestinal Stomas. Additions include chapters on anatomy and physiology, biliary stomas, pediatric ostomies, the continent ileostomy, urostomy, laparoscopic stoma construction, stomas in trauma surgery, stomas for antegrade continence enema, percutaneous ostomies, and quality of life. There are also sections on ileostomy, colostomy, enterostomal therapy and on the management of complications of stomas such as management of the high output ostomy, enterocutaneous fistula, parastomal hernia, prolapse, and skin conditions. The Cleveland Clinic pioneered the entire practice of ostomies, beginning in 1858 and continuing to this day as the world's leading academic and clinical center. The editors and contributors are all current or former Cleveland Clinic physicians and instructors. The fundamental focus of the book is not only how to install ostomies, but how to avoid complications and how to treat complications when they arise. Atlas of Intestinal Stomas will be of great value to colorectal and general surgeons, both in practice and in training.

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