Biological Basis of Geriatric Oncology highlights research issues that are specific to geriatric oncology in the field of carcinogenesis and cancer prevention and treatment, based on the biologic interactions of cancer and age. It illustrates the benefit of the principles of geriatrics in the management of cancer in the older individual.

This volume provides a frame of reference for practicioners of any specialties involved in the management of older patients and for oncologists involved in the management of cancer of older individuals. It is a source for basic and clinical scientists exploring the interactions and emerging information of cancer and aging.

This volume reviews the new potential treatments and research in the area of Alzheimer's disease. Special attention is given to international developments in all fields relevant to new drug development. Topics discussed include: progress in the international harmonization of drug development guidelines for dementia drugs; bioethics and law; development of rating instruments; behavioural treatments; and the activities of the Reagan Foundation. The text integrates basic and clinical research findings, and provides evaluation of new approaches to therapy by world leaders in the field. The potential benefit for Alzheimer patients and families resulting from these research programmes, from molecular biology to clinical pharmacology, is reviewed and evaluated.

With people living longer, often with chronic illnesses and disabilities, it is becoming increasingly important to understand how depression, disability, and physical illnesses are interrelated, the mechanisms underlying these interrelationships, and their implications for diagnosis and treatment. This volume synthesizes a carefully selected portion of the knowledge about physical illness and depression that has emerged during the past twenty years.

The aim of this book is to present current views about physical activity and the benefits of physical activity in preventing and ameliorating various health conditions that are of worldwide concern. This book was developed as a compilation of the accomplishments of the five-year Global COE (Center of Excellence) "Sport Sciences for the Promotion of Active Life" Program at the Faculty of Sport Sciences of Waseda University, Saitama, Japan. The first part establishes the research methodology and discusses the current status of physical activity. Topics covered include the prevalence of physical inactivity and highly sedentary behavior in different populations as well as strategies that can be adopted to promote physical activity. The second part focuses on the physiological effects of physical activity. Topics covered include physiological responses to exercise by the autonomic nervous system, the endocrine system, vascular functioning, postprandial blood glucose control, and inflammatory processes. The relationship between exercise and appetite is discussed, as is the influence of exercise on food intake and weight regulation. Additionally, the influence of exercise on protein regulation and posttranslational modifications is introduced. The final part discusses the role of physical activity in preventing lifestyle-related health issues and improving the quality of life, especially for the elderly. The contents should be of interest to anyone who is concerned with the human physiologic response to exercise and the promotion of healthy lifestyles, including sports and exercise science researchers as well as those involved with medicine, public health, physiology, nutrition, and elder care.

The Owner's Manual for Your Eyes: The most comprehensive guide to taking care of vision. In The Eye Book, specialist Dr. Gary H. Cassel presents readers with trusted, evidence-based information they can rely on to protect vision and learn more about how to treat any eye problems that come up. This easy-to-understand volume takes a step-by-step approach, providing an overview of the eye's anatomy, a tour of healthy vision, and an explanation of what steps readers and health care providers should take to address vision issues. Drawing on years of clinical experience with patients, Cassel also looks at eye complications associated with common medical conditions (for example, diabetes) along with the best treatments for eye conditions, such as cataracts and glaucoma. Now in its second edition, this bestselling book continues to provide the interested reader, along with nurse practitioners, physician assistants, internists, and family doctors, with practical information about * eyeglass materials, contact lenses, and refractive surgeries (including LASIK) to improve vision * tips to spot and treat common eye irritations and infections, including conjunctivitis ("pink eye") * advice about when people should take care of an eye problem on their own and when they need to consult with an expert * what people (and their health care providers) can do about blurriness, dry eyes, eye strain, eye allergies, and floaters * how vision problems may be a sign of other health conditions, including thyroid problems and multiple sclerosis * which medications may affect vision * what people within and outside of the medical field need to know about macular degeneration and low vision Richly illustrated and engagingly written, this edition features special bonus material, including a chapter on cosmetics and the eye, FAQs ("Can cataracts grow back after cataract surgery?"; "Will I go blind from my glaucoma?"), and a handy symptom index that allows readers to research topics by the presentation of an eye problem. Useful for everyone, including general medical professionals who want to learn more about the health of the eyes, this up-to-date, in-depth, and authoritative book will serve as a users' manual for the eyes and help promote better vision for a brighter tomorrow.

Drug-related problems in the elderly is intended to serve as a source of information and clinical support in geriatric pharmacotherapy for students as well as all health care professionals, e.g. physicians, nurses and pharmacists. Pharmacotherapy is of great importance to all mankind. Drugs are however powerful and must be handled appropriately. This is especially important for elderly patients. Drug-related problem is not a major subject in most university programmes in medicine or pharmacy. When there is no speci c course, there is often no book covering the topic. In our view, as teachers at various university courses, there has been a shortage of literature that re ects the most important aspects of drug-related problems in the elderly. Medical practitioners, nurses and pharmacists, need to have this knowledge to be able to serve their patients in the best way. This book covers most aspects of drug-related problems in the elderly. With b- ter knowledge of drug-related dif culties and risks we hope that elderly will have fewer drug-related problems and bene t more from their pharmacotherapy.

A medical expert answers your common questions about memory loss, causes of dementia, diagnosis, prevention, treatment, and more. Perhaps someone in your family has been diagnosed with Alzheimer disease-or maybe you worry about developing memory loss yourself. In Is It Alzheimer's?, Dr. Peter V. Rabins, a top expert in the field, educates readers by answering 101 often-asked questions about memory loss and dementia. Written in a conversational, easy-to-use Q&A style, the book is organized into seven unique sections. A companion to the best-selling The 36-Hour Day, which Dr. Rabins coauthored, this book discusses * how to distinguish typical memory loss from early dementia * how dementia is diagnosed * what factors play a role in the progression of dementia * whether it's possible to lower your risk of developing Alzheimer disease or dementia * how to improve the quality of life of people with dementia * how to assess long-term care facilities and nursing homes * available treatments, including medication * how to explain the symptoms of Alzheimer disease and dementia to others * how to provide caregivers with psychological and emotional support * and much more Aimed at friends and family members of the estimated 5.1 million US adults with dementia, as well as adults who are concerned about developing dementia, the book offers helpful directions and comfort. Is It Alzheimer's? is a quick, accessible, and essential reference for anyone who hopes to navigate the confusion of dementing illnesses.

It is with great pride that the Psychologists in Long Term Care (PLTC) have sponsored The Professional Educational Long-Term Care Training Manual, and now its second iteration, Geropsychology and Long Term Care: A Practitioner's Guide. Education of psychologists working in long-term care settings is consistent with PLTC's mission to assure the provision of high-quality psychological services for a neglected sector of the population, i.e., residents in nursing homes and assisted-living communities. To this end, direct training of generalist psychologists in the nuances of psychological care delivery in long-term care settings has been a major priority. It is a tribute to the accelerating nature of research in long-term care settings that a revision is now necessary. After all, the Professional Educational Training Manual's initial publication date was only in 2001. However, in the intervening years, much progress has been made in addressing assessment and intervention strategies tailored to the needs of this frail but quite diverse population. It is so gratifying to be able to say that there is now a corpus of scientific knowledge to guide long-term care service delivery in long-term care settings.

This book brings together state-of-the-art research on successful aging in Asian populations and highlights how the factors that contribute to successful aging differ from those in the West. It examines the differences between the Asian and Western contexts in which the aging process unfolds, including cultural values, lifestyles, physical environments and family structures. In addition, it examines the question of how to add quality to longer years of life. Specifically, it looks at ways to promote health, preserve cognition, maximize functioning with social support and maintain emotional well-being despite inevitable declines and losses. Compared to other parts of the world, Asia will age more quickly as a result of the rapid socioeconomic developments leading to rising longevity and historically low fertility rates in some countries. These demographic forces in vast populations such as China are expected to make Asia the main driver of global aging in the coming decades. As a result, researchers, professionals, policymakers, as well as the commercial sector, in both East and West, are increasingly interested in gaining a deeper understanding of aging in Asia.

Cardiovascular drug therapy has markedly progressed in the recent decades. Not only have new drugs been introduced to clinical practice, but new classes of drugs have been developed. While in 1960 the practicing cardiolo gist had a selection of about only ten drugs, in 1987 about 150 drugs are routinely used in cardiovascular diseases. Elderly patients, however, usually do not enjoy the full benefit of this progress. This might be due to lack of knowledge, a conservative approach, or the worldwide tendency not to try new drugs in the elderly. It is now clear that the majority of patients that will be treated in car diovascular clinics will be, in the near future, elderly patients. Even now, elderly patients form about one-third of the patients with cardiovascular diseases. These patients are approached, however, according to criteria devel oped for younger populations. This is despite the fact that elderly patients differ from younger ones in most aspects, including pathology, epidemiol ogy, pathophysiology, diagnostic approach, management, pharmacology, pharmacokinetics, rehabilitation, and supportive treatment. It is the purpose of this book to present to the clinician all drugs with which there is clinical experience in the elderly or which might be potentially useful for the elderly with cardiovascular diseases. The data are presented without the authors taking a position. This should allow the clinicians to make their own selection and individualize treatment, vii viii Preface based on a wide data base. Comparative data are presented only when specific comparative studies were performed."

This book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as: how anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing.

Assisting someone with Alzheimer s disease or another illness that causes dementia is incredibly demanding and stressful for the family. Like many disabling conditions, Alzheimer s disease leads to difficulty or inability to carry out common activities of daily life, and so family members take over a variety of tasks ranging from managing the person s finances to helping with intimate activities such as bathing and dressing.

Key coverage in "Caregiving for Alzheimer s Disease and Related Disorders" includes:

Early diagnosis and family dynamics
Emotional needs of caregivers
Developmentally appropriate long-term care for people with Alzheimer s
Family caregivers as members of the Alzheimer s treatment Team
Legal and ethical issues for caregivers
Faith and spirituality
The economics of caring for individuals with Alzheimer s disease
Cultural, racial, ethnic, and socioeconomic issues of minority caregivers
Advances in Alzheimer s disease research

"Caregiving for Alzheimer s Disease and Related Disorders" offers a wealth of insights and ideas for researchers, practitioners, and graduate students across the caregiving fields, including psychology, social work, public health, geriatrics and gerontology, and medicine as well as public and education policy makers."

There is a near-universal folk saying that everyone wishes to live a good long life, but no one wishes for old age. More contemporarily, the rock and roll band, Little Feat, sang, "You know that you're over the hill when your mind's making promises your body can't fill. " This book is about the good long life. It is a book about primary prevention strategies in the aging process; it is not about preventing that process. It is not about being old. Instead, it is about the things that individuals - and the helping professionals who provide them with counsel and assistance - can do to prevent the preventable problems of advancing age, and to better manage those changes in functioning that cannot be prevented. In short, it is about extending all our capacities to the fullest so that we can better keep all those promises that we make to ourselves and others. Aging is a life-long process. We focus here on the changes that are taking place in our selves and in our society as we age. In particular, we focus on what we can do to affect these changes by the choices we make and how we live. This book offers primary prevention strategies for mature and older adults, with the recognition that mature adulthood starts as soon as we are old enough to truly appreciate our active role in our own aging processes.

Gerontology is a multidisciplinary field, and this bibliography provides a multidisciplinary perspective on research on aging. The volume begins with an introductory chapter that desribes the range of interests to be found in gerontology, discusses the core concepts, and directs the reader to appropriate journals and handbooks. The bibliographic chapters that follow provide information on the most important works related to particular areas of gerontological research. Included are bibliographies on caregiving and health care, rituals related to death and dying, sleep disorders, Alzheimer's Disease, coronary disease, and the use of growth hormone in aging research. The chapters reflect social, anthropological, biological, ethical, and medical views. Each chapter begins with a brief essay on the latest trends in the field, and each entry includes a citation and a descriptive and evaluative annotation. Detailed indexes add to the usefulness of the volume.

This is the new and fully revised third edition of the well-received text that is the benchmark book in the field of nutrition and aging. The editors (specialists in geriatric nutrition, medical sociology, and clinical nutrition, respectively) and contributors (a panel of recognized academic nutritionists, geriatricians, clinicians, and other scientists) have added a number of new chapters and have thoroughly updated the widely acclaimed second edition. This third edition provides fresh perspectives and the latest scientific and clinical developments on the interaction of nutrition with age-associated disease and provides practical, evidence-based options to enhance this at-risk population's potential for optimal health and disease prevention. Chapters on a wide range of topics, such as the role of nutrition in physical and cognitive function, and coverage of an array of clinical conditions (obesity, diabetes, heart failure, cancer, kidney disease, osteoporosis), compliment chapters on food insecurity, anti-aging and nutritional supplements, making this third edition uniquely different from previous editions. Handbook of Clinical Nutrition and Aging, Third Edition, is a practical and comprehensive resource and an invaluable guide to nutritionists, physicians, nurses, social workers and others who provide health care for the ever-increasing aging population.

Although this monograph "Dependency o r interdependency in old age" is not the first publication o f the European Social Sciences Research C- mittee (ESSRC) o f the International Association o f Gerontology, I a m happy, as former chairman o f the Committee (1964-1975), to introduce this book to the readers, together with the present chairman. So far the activities o f the Committee have consisted o f co-operating in organizing the scientific programme o f the tri-annual congresses o f the International Association o f Gerontology (lAG), and in organizing sm- ler o r bigger symposia and colloquia for social gerontologists. Sometimes these meetings were mainly organized for European researchers only, sometimes several concurrent colloquia took place in which Americans and o t h e r non-Europeans participated. T h e Committee, the oldest o f the lAG, was established at a scientific meeting in 1954 at Sheffield (U. K. ) A f t e r that year colloquia were held in 1956 near Copenhagen 1 (Denmark), in 1957 at M e r a n o2 (Italy), in 1959 at Assisi (Italy), in 1960 a t Berkeley (Cal.

Late life is characterized by great diversity in memory and other cognitive functions. Although a substantial proportion of older adults suffer from Alzheimer's disease or another form of dementia, a majority retain a high level of cognitive skills throughout the life span. Identifying factors that sustain and enhance cognitive well-being is a growing area of original and translational research. In 2009, there are as many as 5.2 million Americans living with Alzheimer's disease, and that figure is expected to grow to as many as 16 million by 2050. One in six women and one in 10 men who live to be at least age 55 will develop Alzheimer's disease in their remaining lifetime. Approximately 10 million of the 78 million baby boomers who were alive in 2008 can expect to develop Alzheimer's disease. Seventy percent of people with Alzheimer's disease live at home, cared for by family and friends. In 2008, 9.8 million family members, friends, and neighbors provided unpaid care for someone with Alzheimer's disease or another form of dementia. The direct costs to Medicare and Medicaid for care of people with Alzheimer's disease amount to more than $148 billion annually (from Alzheimer's Association, 2008 Alzheimer's Disease Facts and Figures). This book will highlight the research foundations behind brain fitness interventions as well as showcase innovative community-based programs to maintain and promote mental fitness and intervene with adults with cognitive impairment. The emphasis is on illustrating the nuts and bolts of setting up and utilizing cognitive health programs in the community, not just the laboratory.

Distinguished physicians critically review the clinical consequences of the endocrinological changes that occur with aging-in both men and women-and examine the use of hormonal therapy to reduce them. Topics range from bone disease and water balance in all older people, to androgen deficiency in aging males, gynecomastia, and menopause. The authors also discuss Type II diabetes in persons over 65, emphasizing the cognitive benefits of good glycemia control, and the interaction of nutrition and metabolism, focusing on hypocholesterolemia, obesity, the anorexia of aging, trace elements, and vitamins. The aging of the sympathetic nervous system and its impact on hypertension in the elderly is also covered. Timely and authoritative, Endocrinology of Aging offers endocrinologists, geriatricians, and primary care physicians critical insight into the endocrine problems of our rapidly growing elderly population.

The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014), will focus on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments and will provide an international forum for the latest scientific discoveries, medical practices and care initiatives. Advances information technologies will be discussed along with their implications for various research, implementation and policy concerns. In addition, the conference will address European and global issues in the funding of long-term care and medico-social policies regarding elderly people. GeNeDis 2014 takes place in Corfu, Greece, 10-13 April 2014. This volume focuses on the sessions that address neurodegenerative diseases.

In this book, leading authors in the field discuss the habitats of tomorrow. These habitats will be connected through autonomous and assistive systems, turning habitats into health resorts. This book discusses how assistance technologies enable a smooth transition from comfortable health support to medical or nursing care. The contributions have been chosen and invited at the 9th AAL congress, Frankfurt.

Leaders in neuropsychology, behavioral neurology, speech and language science, neuropsychiatry, and many other disciplines contribute to this volume, the first comprehensive review of knowledge in the field. They discuss a wide range of disorders, including areas of recent research - such as frontal lobe dementias and the neuropsychological aspects of late life depression - and clinical problems typically given insufficient consideration in other works, such as seizure disorder, head injury, and mental retardation. Normal aging is also covered in detail, and assessment procedures and clinical interventions are given thorough treatment. Other highlights include discussions of guardianship and caregiving personality and behavior, psychotic disorders, Alzheimer's, and head trauma.

There is no group of individuals more iconic of 1960s counterculture than the hippies - the long-haired, colorfully dressed youth who rebelled against mainstream societal values, preached and practiced love and peace, and generally sought more meaningful and authentic lives. These 'flower children' are now over sixty and comprise a significant part of the older population in the United States. While some hippies rejoined mainstream American society as they grew older, others still maintain the hippie ideology and lifestyle. This book is the first to explore the aging experience of older hippies by examining aspects related to identity, generativity, daily activities, spirituality, community, end-of-life care, and wellbeing. Based on 40 in-depth interviews with lifelong, returning, and past residents of The Farm, an intentional community in Tennessee that was founded in 1971 and still exists today, insights into the subculture of aging hippies and their keys to wellbeing are shared.