Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. A logical organization makes it easy to find essential information. Complete coverage of the basic fundamentals of pharmacology such as ocular drug delivery and ocular drug formulations. Comprehensive reviews of the pharmacology of specific classes of agents such as the cycloplegics, antiglaucoma drugs, anti-inflammatory drugs, ocular irrigating solutions, and contact lens care products. In-depth information on ocular drugs used in clinical practice, including chapters on drugs used to treat eyelid disorders, lacrimal diseases, conjunctiva diseases, corneal diseases, allergies, uveitis, postoperative cataract, retinal diseases, and glaucoma. Coverage of ocular toxicology, including drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies. Completely revised and updated content that reflects the latest advances in pharmacology. Updated information on post-operative drugs, including LASIK follow up medications. Expanded coverage in the chapters on Anti-infective Drugs, Anti-allergy Drugs and Decongestants, and Lubricants and Other Preparations of Ocular Surface Disease that includes the latest advancements in antibiotics and medications used to treat allergies and dry eye. A dosage quick reference guide on the inside front cover for quick and easy access. Information on the use of herbal medications.

This second Uveitis volume provides the ophthalmologist with the most current understanding of the pathogenesis of the most frequent immune-mediated disorders of the eye and a practical approach to these diseases. It fills the gap between textbooks and original research publications and focuses on clinical aspects of inflammatory eye diseases. It covers a broad spectrum, including diseases affecting the conjunctiva, sclera and cornea, as well as intraocular inflammation, and it includes basic research aspects, such as immune mechanisms and genetics. The book is easy to read with highly structured core messages and summaries for the clinician.

This is the first textbook to offer a comprehensive account of ocular prosthetics and the evidence used to underpin and support this field of healthcare. It does so by bringing together information from ophthalmology, prosthetic eye and contact lens literature, and from experts actively engaged in these fields. The book describes the psychological, anatomical and physiological aspects of eye loss as well as surgical procedures for removing the eye, patient evaluation, constructing prosthetic eyes (including prosthetic and surgical techniques for dealing with socket complications), the socket's response to prosthetic eyes, prosthetic eye maintenance and the history of prosthetic eyes. Though primarily intended for prosthetists, ophthalmologists, ophthalmic nurses, optometrists and students in the fields of ocular medicine, maxillofacial medicine and anaplastology, the book also offers a useful resource for other health workers and family members who care for prosthetic eye patients, and for those patients seeking a deeper understanding of the issues affecting them than they can find elsewhere.

In this 5th edition of the concise and clearly written best selling title, all the chapters have been thoroughly updated and expanded, particularly the sections on the retinal, macular, phacoemulsification, lasik, new equipment and ophthalmic drugs.The book is generously illustrated with more than 200 colour pictures and is an excellent volume for medical students, general practitioners, ophthalmic students and all paramedical personnel who have to deal with common eye diseases.

In this 5th edition of the concise and clearly written best selling title, all the chapters have been thoroughly updated and expanded, particularly the sections on the retinal, macular, phacoemulsification, lasik, new equipment and ophthalmic drugs.The book is generously illustrated with more than 200 colour pictures and is an excellent volume for medical students, general practitioners, ophthalmic students and all paramedical personnel who have to deal with common eye diseases.

The atlas of the Light and Specular Microscopy of the Cornea, particularly of the corneal endothelium presents photographs of healthy and pathological corneas, as well as corneas prepared for grafting. Photographs are taken from donor or patient's corneas. The first part section of the atlas shows healthy corneas and its particular layers: the epithelium (superficial and basal cells, subepithelial nerve plexus), stroma and keratocytes, and the endothelium. Blood vessels or palisades of Vogt in limbus are shown as well. The second part section that shows corneas processed for grafting is focused focuses on the endothelial layer. Main causes of exclusion of corneas from grafting, such as the presence of dead cells, polymeghatism, pleomorphism, cornea guttata or stromal scars have been shown. The third part section of the atlas shows corneas before and after storage in tissue cultures or hypothermic conditions with the aim to assess its suitability of for tissue for grafting. The last final section contains photographs of pathological corneal explants

Written by a practicing ophthalmologist, this book explains the eye and how it develops and functions—or can malfunction, especially as we age—and what our options are to maximize or retain eye health. Dr. Kitchen also explains the many treatments and surgical options available, as well as myths and false beliefs or promises that are common in relation to eye health and treatments today. Dr. Kitchen describes time-tested, proven techniques, as well as new treatments and surgeries changing the nature of eye care, including refractive surgery options. He also explains common problems from red eye to macular degeneration, and spotlights beliefs and treatment claims that are uninformed or downright deceptive. His goal is to help Boomers and parents make well-informed decisions about eye care for themselves and their family members, and also to help aging consumers retain their visual health. Appendices include a glossary of eye and eye care terms. The topics addressed include eye anatomy, examinations, medications, treatments, and surgery. Conditions described range from dry eye to ocular migraines, lazy eye, cataracts, glaucoma, and eye cancer.

The second volume of "Cataract and Refractive Surgery" in the Essentials in Ophthalmology series provides new information on cataract and refractive surgery. The chapters discuss new techniques and technology. The emphasis is on areas that are rapidly evolving and essential to sophisticated clinical practice. The book has a well-structured text and design, and is quick and easy to read. It bridges the gap between primary literature and daily practice. This book will help clinicians provide the best results for their cataract and refractive surgical patients and is also indispensable for continuous education and advanced training.

Corneal topography is a non-invasive medical imaging technique for mapping the surface curvature of the cornea, the outer structure of the eye. This procedure may be carried out with a Pentacam, which uses a rotating camera to create a 3D image of the anterior of the eye. The third edition of this bestselling book has been fully revised to present ophthalmologists with the latest advances in the interpretation of corneal topography using the Pentacam. The book begins by discussing standardisation of capturing the corneal image and offers guidance on systemic interpretation. The text presents two new algorithms – the practical subjective scoring system (PS3) for laser-based refractive surgery and the practical subjective IOL selection (PSIS) for lens-based refractive surgery. New categorisation of ectatic corneal diseases, correlation of tomographic findings and their clinical applications, and the importance of corneal wave front, are covered in depth. The book concludes with four clinical cases to assist learning. Authored by recognised ophthalmic specialist Mazen Sinjab, the comprehensive text is further enhanced by clinical photographs and figures. Key points Third edition of bestselling guide to interpretation of corneal topography using Pentacam Fully revised with latest advances in the field and two new algorithms Authored by renowned ophthalmic specialist Mazen Sinjab Previous edition (9789351523970) published in 2015

During the past two decades, our understanding of the molecular genetics of inherited eye diseases, their classification, and management has undergone a huge expansion as the field of human genetics has benefited from technological advances and increased interest by physicians and scientists in all fields. As a result, the amount of clinical and basic-science information on inherited systemic and eye diseases has become so large that general ophthalmologists, ophthalmic subspecialists, and physicians in other fields have found it difficult to keep up. This volume will act as a guide because it catalogues all the latest information about genetic diseases that involve the eye and presents it in a practical and accessible format. After an introductory chapter that reviews basic clinical and molecular-genetic principles, individual diseases and groups of diseases are listed alphabetically in order to make it as easy as possible to search for an entry. The material in each entry is a synthesis of numerous articles and reviews on the topic, accompanied by at least one high-quality illustration, at least one webpage of a patient support group or other organization related to the disease, and references that provide the original description of the disease, an excellent review, or useful illustrations. There is also a companion website containing electronic copies of all the illustrations to make it easy to use them in lectures. Health-care professionals who need immediate access to clinical and basic-science information on inherited systemic and eye diseases will find this volume indispensable.

This book highlights the unique aspects of oncologic ophthalmology as a medical and surgical discipline practiced at a comprehensive cancer center. Multi-disciplinary management of ocular, orbital and adnexal cancers are highlighted using simple and tried-and-true algorithms. In addition, ocular problems caused as a direct result of cancer treatment are reviewed using illustrative photographs and case presentations. The content is provided by full-time ophthalmology faculty and fellows at M. D. Anderson Cancer Center. Experts in complementary disciplines such as ophthalmic pathology, dermatopathology, radiation oncology, radiology, and other surgical subspecialties have brought their unique perspective to each chapter. The book is abundant with clinical photographs as well as interesting case presentations that will help the clinician correctly diagnose cancers of the orbit, eye, and adnexal structures, initiate appropriate management, as well as recognize and treat common ocular complications of cancer therapy.

Series:

Highly practical and clinically relevant

Ophthalmology series is indispensable for continuous education and advanced training

All editors with international reputation and contributing authors with expertise in their topics

Reader-friendly format: Well-structured text and design, quick and easy to read

Richly illustrated with numerous tables and color photos

Bridges the gap between primary literature and daily practice

Every 2nd year each subject is refreshed with timely information about the new development in the specialized field

This volume:

Appeals not only to Ophthalmologists, but also to Pediatricians

Gives quick and practical introduction to the most up-to date treatment options in pediatric ophthalmology

Only addresses new developments of the past 2 years

Covers 3 main topics: Genetics, Pediatrics and Neurophthalmology, while competing titles focus on one of these subspecialties

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This popular and successful book, having been translated into major languages, has now been fully revised, updated and expanded into a third edition. The text: provides a step by step guide to all the commonly performed procedures and techniques includes the very latest information on new techniques and materials, such as those for cosmetic surgery contains new chapters covering techniques and management of corneal exposure is extensively illustrated with clear line diagrams to illustrate all the procedures described there is an expanded chapter on lacrimal surgery by Mr Richard Welham still retains its original aim to provide a systematic approach and an invaluable practical guide for all those who operate on eyelids From the reviews of previous editions: 'Collin has managed to include those extremely pertinent points which are important to the operating surgeon... the book is full of a wealth of information on eyelid surgical procedures.' Plastic and Reconstructive Surgery '...a really excellent book packed with detail... I would recommend that a copy of this book be kept in all eye theatres...' Journal of the Irish College of Physicians and Surgeons The most efficient, hands-on resource of its kind. Provides step-by-step guidance on most of the commonly performed surgical procedures and techniques Clear line diagrams illustrate all of the procedures described. Systematically organized for quick and easy reference. New coverage of ectropion adjustable sutures in ptosis surgery, eyelid tumor management and clearance, thyroid eye disease, orbital implants and socket surgery, new coverage of the management of lower lid blepharoplasty and more.

This consolidated reference book addresses the various aspects of nano biomaterials used in ophthalmic drug delivery, including their characterization, interactions with ophthalmic system and applications in treatments of the ophthalmic diseases and disorders. In the last decade, a significant growth in polymer sciences, nanotechnology and biotechnology has resulted in the development of new nano- and bioengineered nano-bio-materials. These are extensively explored as drug delivery carriers as well as for implantable devices and scaffolds. At the interface between nanomaterials and biological systems, the organic and synthetic worlds merge into a new science concerned with the safe use of nanotechnology and nano material design for biological applications. For this field to evolve, there is a need to understand the dynamic forces and molecular components that shape these interactions. While it is impossible to describe with certainty all the bio physicochemical interactions at play at the interface, we are at a point where the pockets of assembled knowledge are providing a conceptual framework to guide this exploration, and review the impact on future product development. The book is intended as a valuable resource for academics and pharmaceutical scientists working in the field of polymers, polymers materials for drug delivery, drug delivery systems and ophthalmic drug delivery systems, in addition to medical and health care professionals in these areas.

Ocular toxicity is routinely assessed in toxicology studies conducted for regulatory purposes. Ocular anatomy and physiology and the assessment of ocular toxicity itself can be challenging to scientists involved in the safety assessment of pharmaceuticals, pesticides and other agents. Anatomical and physiological differences between species can impact the nature of ocular effects observed following intended or unintended exposure of ocular tissues to xenobiotics. "Ocular Toxicity in Laboratory Animals" provides a concise reference addressing ocular anatomy and physiology across species that will enhance the design and interpretation of toxicology studies conducted for regulatory purposes.

The book provides an overview of routine and advanced techniques that are used to assess ocular toxicity including slit lamp biomicroscopy, indirect ophthalmoscopy, electrophysiology and imaging methods for the anterior and posterior segments of the eye. Additionally, the book defines the regulatory expectations for pharmaceuticals intended to treat ocular diseases and for other non-pharmaceutical regulated chemicals. With contributions from experts in the field, "Ocular Toxicity in Laboratory Animals" is an authoritative, accessible guide for toxicologists and other scientists involved in conducting toxicology studies for regulatory purposes and/or reviewing data from such studies."

This superbly structured text is designed for practical ease of use. Quick and easy to read, it bridges the gap between primary literature and daily practice in this specialized field. Neuro-ophthalmology encompasses lesions of both the afferent and efferent pathways, which can result from various etiologies, including tumoral, paraneoplastic, vascular, inflammatory, infectious, or hereditary just to name a few. This volume of Essentials in Ophthalmology is dedicated to the review of new developments in neuro-ophthalmology. It has been written by an array of authors with real expertise in the subject. The text includes all the latest developments, including those in diagnosis, physiology, investigations, and in therapeutic options.

Retinal and choroidal angiogenesis are the leading causes of irreversible vision loss in developed countries. For this reason, ocular angiogenesis is an intensely studied process, and the field is advancing at an astounding pace. It has become increasingly difficult to manage the vast amount of information generated by the growing group of interested investigators, thus a resource is needed that distills and summarizes our progress to date. Additionally, novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. Retinal and Choroidal Angiogenesis emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance. The result is a reference work appealing to ophthalmologists interested in clinical applications, as well as to basic scientists interested in the cellular and molecular mechanisms of angiogenesis, both in the context of ocular and non-ocular conditions.

This outstanding volume in the Essentials in Ophthalmology series presents recent developments in the diagnosis and treatment of corneal disease. Its intention is not to replace the relevant textbooks, but to serve as a bridge between primary and tertiary literature. The superbly structured volume covers a dizzying array of topics including Herpes simplex keratitis; amniotic membrane transplantation for the treatment of corneal ulceration in infectious keratitis; and Chlamydial infection, all three of which are hugely relevant today. All the topics have direct clinical importance and will not only keep ophthalmologists up to date, but will inform them of how to treat their cornea patients with optimal diagnostic and therapeutic procedures.

Muller glial cells ensheath all retinal neurons in vertebrate retinae. There are a multitude of functional interactions between neurons and Muller cells, including delivery of the light stimuli to the photoreceptor cells in the inverted vertebrate retina, a 'metabolic symbiosis' with the neurons, and the processing of visual information. Muller cells are also responsible for the maintenance of the homeostasis of the retinal extracellular milieu (ions, water, neuro-transmitter molecules, and pH). In vascularized retinae, Muller cells may also be involved in the control of angiogenesis, and the regulation of retinal blood flow. Virtually every disease of the retina is associated with a reactive Muller cell gliosis which, on the one hand, supports the survival of retinal neurons but, on the other hand, may accelerate the progress of neuronal degeneration:

Muller cells protect neurons via a release of neurotrophic factors. However, gliotic Muller cells display a dysregulation of various neuron-supportive functions. This contributes to a disturbance of retinal glutamate metabolism and ion homeostasis, and causes the development of retinal edema and neuronal cell death. Moreover, there are diseases evoking a primary Muller cell insufficiency, such as hepatic retinopathy and certain forms of glaucoma. Any impairment of supportive functions of Muller cells, primary or secondary, must cause and/or aggravate a dysfunction and loss of neurons, by increasing the susceptibility of neurons to stressful stimuli in the diseased retina.

Muller cells may be used in the future for novel therapeutic strategies to protect neurons against apoptosis (i.e. somatic gene therapy), or to differentiate retinal neurons from Muller/stem cells. Meanwhile, a proper understanding of the gliotic responses of Muller cells in the diseased retina, and of their protective vs. detrimental effects, is essential for the development of efficient therapeutic strategies that use and stimulate the neuron-supportive/-protective - and prevent the destructive - mechanisms of gliosis.

The first section covers the general assessment and investigation of the squinting patient, before considering whether surgery is the best form of treatment. The second section addresses common squint disorders, describing the conditions and highlighting the surgical options to be considered. The final section provides a step-by-step account of the surgical procedures, indicating when they should be used, and illustrating specific techniques. This is an essential manual for trainees in clinical practice and those preparing for examinations who need to know how to competently manage this commonly encountered disorder. Optometrists will also find it of great value when managing these patients both pre- and post-operatively. Using a problem-oriented approach, diagnosis and assessment of conditions are introduced before addressing treatment options Specific disorders are covered in detail, indicating when to use surgical treatment and which techniques to use The surgical procedures are covered in a step-by-step format with clear line diagrams highlighting the required techniques. A separate chapter covers general and specific surgical complications

Medical technology is a fast growing field. This new title gives a comprehensive review of modern optical technologies alongside their clinical deployment. It bridges the technology and clinical domains and will be suitable in both technical and clinical environments. It introduces and develops basic physical methods (in optics, photonics, and metrology) and their applications in the design of optical systems for use in medical technology with a special focus on ophthalmology. Medical applications described in detail demonstrate the advantage of utilizing optical-photonic methods. Exercises and solutions for each chapter help understand and apply basic principles and methods. An associated website run by the authors will include slides to facilitate the teaching/training of this material, and typical images collected by the described methods, eg videos of endoscopy or navigation, OCT, etc.

This monograph focuses on the use of analysis and processing methods for images from the Corvis (R) ST tonometer. The presented analysis is associated with the quantitative, repeatable and fully automatic evaluation of the response of the eye, eyeball and cornea to an air-puff. All the described algorithms were practically implemented in MATLAB (R). The monograph also describes and provides the full source code designed to perform the discussed calculations. As a result, this monograph is intended for scientists, graduate students and students of computer science and bioengineering as well as doctors wishing to expand their knowledge of modern diagnostic methods assisted by various image analysis and processing methods.

The visual field refers to the total area in which objects can be seen in the side (peripheral) vision when the eyes are focused on a central point. Glaucoma is a condition of the eye in which the optic nerve is damaged due to increased fluid pressure in the eye. If untreated or uncontrolled, glaucoma first causes peripheral vision loss and eventually can lead to blindness. A visual field test is a method of measuring an individual's entire scope of vision, that is their central and peripheral (side) vision. The test is most frequently used to help detect glaucoma but may also be used for detection of central or peripheral diseases of the retina, eyelid conditions such as drooping (ptosis), optic nerve damage and disease, and conditions affecting the visual pathways from the optic nerve to the area of the brain (occipital cortex) where this information is processed into vision. The fourth edition of this comprehensive text provides ophthalmologists and trainees with a guide to the interpretation of visual field tests and subsequent diagnosis and management of ocular disorders. The book has been fully revised and features additional topics including two new classification systems for glaucoma. Nearly 800 clinical photographs and diagrams further enhance learning. Key points Comprehensive guide to interpretation of visual field tests and diagnosis of ocular disorders Fully revised fourth edition featuring many new topics Features nearly 800 clinical photographs and diagrams Previous edition (9788184488661) published in 2008