Modern North American sturgeons and paddlefish are the result of 100 million years of evolution. Once an integral part of aboriginal culture, their numbers were decimated by overfishing and habitat destruction during the past two centuries.

This book details the extensive science aimed at helping these remarkable species recover from the brink of extinction, and describes the historical, biological, and ecological importance of North American sturgeon and paddlefish. The text is enhanced by photographs and detailed line drawings.

This comprehensive volume will be an invaluable resource for researchers, educators, and consultants, in academic and government settings, who work to further scientific understanding of these fishes. No other single compilation has documented current information in such detail.

Providing the information required to understand, advocate for, and supply post-acute vision rehabilitative care following brain injury, Vision Rehabilitation: Multidisciplinary Care of the Patient Following Brain Injury bridges the gap between theory and practice. It presents clinical information and scientific literature supporting the diagnostic and therapeutic strategies applied in a comprehensive overview of current diagnostic and treatment strategies in adult post-brain injury vision rehabilitation. Includes a foreword by Dr. Sue Barry Because post-brain injury rehabilitation works best in a team setting where the entire person can be treated, this text has been carefully designed as a multidisciplinary resource with an emphasis on models for working with the rehabilitation team. The book covers a myriad of topics such as post-brain injury vision rehabilitation; eye movements; binocular dysfunction; visual field loss; visual-spatial neglect; shifts in visual egocenter affecting balance and coordination; visual-vestibular interactions; central vs. peripheral visual attention; as well as deficits in object perception, visual memory, and visual cognition. The book details models that vision specialists working with the rehabilitation team can use to achieve the best success for the patient in rehabilitation; vision rehabilitation concepts and the science from which they have been developed; examples of therapeutic exercises; practice management information for the post-brain injury vision rehabilitation practice; and information on the legal process in which one frequently becomes involved in this type of work. Edited by eminent clinicians, the book highlights the work of contributors who are well-respected academicians and researchers, bringing together the clinical information that enables everyone involved in a brain injury case to grasp the diagnostic and therapeutic strategies.

What surgical advancements have spawned from the evolution of phaco technology? Join the thousands of surgeons who have utilized "Phacodynamics: Mastering the Tools and Techniques of Phacoemulsification Surgery" to understand and benefit from the advantages of phaco technology.

The revised, expanded, and updated "Fourth Edition" of this classic text includes over 300 simple, yet elegant, figures and illustrations detailing the latest machine technologies and surgical techniques. Visual learners...

In addition to examining the intricate relationship between the surgeon and the phaco machine, Dr. Barry Seibel profiles how the most recent advancements in machine technology can enhance your surgical procedures and optimize your results. With schematic figures and illustrations to accompany the detailed descriptions, surgeons can readily identify and distinguish between various flow pumps, vacuum pumps, and ultrasound power modulations. Surgery can then be customized moment by moment for each individual patient to maximize safety and efficacy.
"Phacodynamics, Fourth Edition" utilizes a simplified approach to explain all the latest advancements in phaco technology and surgery and should be in the hands of all surgeons practicing in this specialized area.
New topics included that are unique to this Fourth Edition:

• Bimanual Microincision Phaco
• Ultrasound Power Modulations including Burst and Pulse Modes
• AquaLase and Laser Surgical Technologies
• Expanded Horizontal Chopping Techniques including PreChop
• Vertical Chopping Techniques and Instrumentation
• Bimanual Irrigation and Aspiration
• Phacodynamic Complications
• Phacodynamics of SurgicalInstrument Design

Clinically-oriented and up-to-date, Dry Eye Diseases focuses on the latest diagnostic techniques, management guidelines, and treatment options for dry eye disorders. This consolidated resource provides guidance on the clinical assessment of patients presenting with dry eye symptoms as well as a global perspectives on the use of FDA and off-label products. Practicing and trainee ophthalmologists and optometrists will find this an indispensable resource for understanding this complex disorder. Covers a range of topics, including clinical assessment, pathophysiology, the link between dry eye and system disease, and the use of FDA and off-label products as treatment options for dry eye diseases. Includes a section devoted to the presence of dry eye disease in specific populations, including patients presenting with other ocular conditions, systemic pain conditions, graft-versus-host disease, Sjoegren's syndrome, and meibomian gland dysfunction. Addresses the challenges associated with treating ocular pain not responsive to traditional dry eye disease treatments. Features concise chapters from a team of international chapter authors, providing global perspectives on this common disorder. Consolidates today's available information on this timely topic into a single, convenient resource

Ophthalmic Anaesthesia is a new textbook written by an international group of authors who are recognized experts in the fields of anaesthesia and ophthalmology. Covering the entire subspecialty of anaesthesia for surgery of the eye, the book offers chapters on a variety of subjects including: the history of ophthalmic anaesthesia, physiology and pharmacology, anatomy, pre-operative assessment, paediatric anaesthesia, orbital regional anaesthesia, general anaesthesia, complications, high-volume cataract surgery, and future developments. Written by both academicians and experienced clinicians, this is a well-referenced and illustrated text describing the techniques used in the anaesthetic management of patients undergoing the most commonly performed surgical procedures in the world.

This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs.

Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and implant dosage formsRefillable and microneedle devicesIntravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of deliveryPhysical methods including iontophoresis for drug deliveryRational selection of routes of administration and delivery systemsNoninvasive and continuous drug monitoring Regulatory path to drug product developmentClinical endpoints for drug product developmentEmerging and existing drugs and drug targets

"Drug Product Development for the Back of the Eye" is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devicesIntravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of deliveryPhysical methods including iontophoresis for drug deliveryRational selection of routes of administration and delivery systemsNoninvasive and continuous drug monitoring Regulatory path to drug product developmentClinical endpoints for drug product developmentEmerging and existing drugs and drug targets

"Drug Product Development for the Back of the Eye" is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. Refillable and microneedle devicesIntravitreal, suprachoroidal, intrascleral, transscleral, systemic, and topical routes of deliveryPhysical methods including iontophoresis for drug deliveryRational selection of routes of administration and delivery systemsNoninvasive and continuous drug monitoring Regulatory path to drug product developmentClinical endpoints for drug product developmentEmerging and existing drugs and drug targets

"Drug Product Development for the Back of the Eye" is authored by renowned ocular drug delivery experts, representing academic, clinical, and industrial organizations and serves as indispensable resource for ophthalmic researchers, drug formulation scientists, drug delivery and drug disposition scientists, as well as clinicians involved in designing and developing novel therapeutics for the back of the eye diseases. This book is also relevant for students in various disciplines including ophthalmology, pharmaceutical sciences, drug delivery, and biomedical engineering. "

Describes the optical structure and optical properties of the human eye Explains image formation and refraction of the eye Covers interactions between light and the eye, considering transmission, reflection and scatter in the media of the eye and at the fundus Covers aberrations and image quality of the eye

For more than 30 years, the visual cortex has been the source of new theories and ideas about how the brain processes information. The visual cortex is easily accessible through a variety of recording and imagining techniques and allows mapping of high level behavior relatively directly to neural mechanisms. Understanding the computations in the visual cortex is therefore an important step toward a general theory of computational brain theory.

In this book the authors relate and discuss the idea that perceptual processes can be considered at many levels. A phenomenon that appears at one level may not be the same as a superficially similar phenomenon that appears at a different level. For example "induced motion" can be analyzed in terms of eye movements or at the retinal level or at a much higher cognitive level: how do these analyses fit together? The concept of levels also makes us think of the flow of information between levels, which leads to a consideration of the roles of top-down and bottom-up (or feed-forward, feed-back) flow. There are sections devoted to vestibular processing, eye movement processing and processing during brightness perception. The final section covers levels of processing in spatial vision. All scientists and graduate students working in vision will be interested in this book as well as people involved in using visual processes in computer animations, display design or the sensory systems of machines.

We are excited to bring together recent research on the molecular biology of Axenfeld-Rieger syndrome (ARS) disorders. In the following chapters we will review and provide direct evidence for the molecular basis of this group of heterogeneous disorders, which include Rieger syndrome and Rieger anomaly. While ARS patients were initially diagnosed in the early 1930s the genetic basis for ARS was unknown until the recent identification of chromo- somal loci associated with this genetic disorder. In the mid-1990s Drs. Jeffrey C. Murray and Elena V. Semina identified PITX2 through positional cloning tech- niques as a gene associated with ARS. These researchers were able to iden- tify point mutations in PITX2 that were linked with ARS patients. ARS patients presented clinically with several developmental anomalies that fur- ther provided clues about the function of the PITX2 homeobox tran- scription factor. The phenotypic variability of ARS patients indicates that PITX2 can participate with many other faaors to control normal development processes. The hallmarks of ARS developmental anomalies are eye, tooth and umbilical defects. However, abnormal pituitary, heart, and craniofacial development are also detected. Thus, ARS patients provided the first link of PITX2 involvement in the development of these organs and structures. Some of these anomalies are recapitulated in epigenetic and genetic mouse, chick, zebrafish and frog studies which will be reviewed in the following chapters.

This second Glaucoma volume of the Essentials in Ophthalmology series, like the first, provides a comprehensive picture of recent progress in both basic clinical research and applied clinical science in the study of glaucoma. Rather than a replacement for traditional textbooks on glaucoma, this volume serves as a conceptual bridge between original research and textbook presentation. The book encompasses frequently unmentioned aspects of therapy, including adherence, persistence and health economics. Glaucoma II provides the reader with diverse and salient topics reflective of the contemporary, evidence-based approach to the study, treatment and management of glaucoma.

Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.

Proceedings of the Seventh Symposium of the International Research Group on Colour Vision Deficiencies Held at Centre Medical Universitaire, Geneva, Switzerland, 23-25 June, 1983

This comprehensive report on sight correction through laser surgery provides the practitioner with solid background information from top industry researchers. Carefully illustrated, it details the latest techniques and clinical results in wavefront technology for laser surgery, which is now defining a new standard of practice. This second edition has been significantly expanded to include in-depth descriptions of important new advances as well as glimpses of what the future holds. The book will be indispensable to all wishing to expand their knowledge of customized refractive surgery with an understanding of the underpinning technology.

Ocular Telehealth focuses on the latest guidance for the implementation and use of telemedicine in eye care settings. Detailing both benefits and challenges, this consolidated resource combines evidence-based literature with expert perspectives. Practicing and trainee ophthalmologists and optometrists will find this an indispensable resource for understanding the current issues and opportunities surrounding the integration of telemedicine into standard clinical practice. Covers a range of topics, including remote patient monitoring, video communication skills, technology selection, and best practices for ensuring patient data protection. Addresses the challenges associated with integrating telemedicine into clinical practice including reimbursement issues, ethical/legal considerations, implementation strategies, and patient engagement. Features concise chapters written by a team of thought leaders on telemedicine. Consolidates today's available information on this timely topic into a single, convenient resource. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book addresses the issues relating to a wide variety of ocular diseases from which millions of people suffer. Long-term challenges include visual impairment and ocular blindness. Certain ocular diseases are quite rare, whereas others, such as cataracts, age-related macular degeneration (AMD), and glaucoma, are very common, especially in the aging population. A rapid expansion of new technologies in ocular drug delivery and new drug candidates, including biologics, to treat these challenging diseases in the retina and posterior segments of the eye have recently emerged. These approaches are necessary because the eye has many unique barriers to drug delivery. Thus, this timely reference Drug Delivery for the Retina and Posterior Segment Disease compiles and analyzes recent advances in the research and development of drug delivery systems for retina and posterior segment diseases of the eye, with an emphasis on the use of implantable devices, iontophoresis as well as micro- and nanoparticles.

Proceedings of the International Symposium, Munich, FRG, 16-18 September, 1982

This volume details the latest technology in treating eye injuries and infections. It provides insight into the most up-to-date and established treatment options. The volume focuses on what can currently be achieved with a variety of ocular prostheses as well as what the future holds. Coverage reviews issues such as intraocular lens implants, biocompatibility of materials, retinal implants, testing models, and software designs.