Intraocular inflammation is particularly difficult to diagnose and treat, often resembling a complex puzzle of patient history, symptoms, imaging, and laboratory test results. Clinical Cases in Uveitis: Differential Diagnosis and Management is a unique, case-based resource designed to help you navigate the range of challenging manifestations and presentations that often mimic other diseases. More than 90 real-world uveitis cases are presented in a highly templated, easy-to-follow format, along with step-by-step guidance on the right patient questions, assessment, differential diagnosis, testing, management, and follow-up care. Provides a variety of patient presentations and scenarios and unique clinical situations that mirror day-to-day practice. Covers current diagnostic imaging modalities, including optical coherence tomography (OCT), optical coherence tomography angiography, fluorescein angiography (FA), and indocyanine green angiography (ICG). Features diagnostic and management algorithms that assist in differential diagnosis and decision making for even the most complex cases, including those in which the patient does not improve as expected, prompting a reassessment of diagnosis and management. Contains approximately 250 high-quality images, including color anterior segment photographs, color fundus photographs, OCT images, and angiograms. Discusses distinguishing infectious from non-infectious inflammation; when and how to start systemic immunosuppressive therapy; diagnostic criteria and management of "white dot syndromes"; pediatric uveitis; masquerade syndromes, including inherited retinal degenerations, malignancies, and paraneoplastic syndromes; and much more. Includes the authors' specific thought processes and approach in particularly challenging cases. An excellent resource and study tool for ophthalmology residents and fellows, those studying for oral boards, general ophthalmologists, retina specialists, and more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Advances in Ophthalmology and Optometry reviews the most current practices in both ophthalmology and optometry. A distinguished editorial board, headed by Dr. Myron Yanoff, identifies key areas of major progress and controversy and invites expert ophthalmologists and optometrists to contribute original articles devoted to these topics. Broken into sections, the the third Volume in the series covers topics within each of the following categories: Optometry, Cataracts, Pediatrics, Ophthalmic Pathology & Ocular Oncology, Vitreoretinal Disease, Glaucoma, Neuro-ophthalmology, Oculoplastics, and Uveitis.

Central Serous Chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of CSCR, findings on various imaging modalities, available treatment options, and translational research into new treatment options for CSCR management. This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems (vision), and ophthalmologists. Central Serous Chorioretinopathy (CSCR) is a common disorder across the world with a variable prognosis without any standard of care. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease.

Are you a medical student or resident trying to absorb as much information on the cornea as efficiently as possible? Are you an ophthalmologist who needs fast facts on a specific corneal disease? Reach into your lab coat pocket and pull out The Pocket Guide to Cornea for easy access to the information you need right now. Drs. Terry Kim and Melissa Daluvoy have designed this book as the most effective way to take in the information on the cornea for the entire spectrum of eye care providers. Medical students and residents will be pleased to have this accessible, high-yield handbook during their rotations to familiarize themselves with cornea findings and diagnoses, while seasoned ophthalmologists will be glad to have it as a refresher or quick reference guide to current diagnostic and treatment standards. Contained within The Pocket Guide to Cornea, is the most essential information on the cornea organized in the most efficient ways. Each chapter is arranged in bullet-point style, for quick access to the relevant information, and is accompanied by numerous color photographs to help with recognition and retention. Topics covered: Basic examination techniques Anterior segment testing and imaging Common to rare cornea diseases Common procedures and surgeries The entire spectrum of eye care providers can benefit from the high-yield, quick-access information contained within The Pocket Guide to Cornea,, whether they are learning about the cornea for the first time or they just need a quick refresher on an obscure corneal disease.

Viewing an electronic display screen varies significantly from reading text on paper and human eyes often suffer for it. Featuring cutting-edge research in the field of visual ergonomics, Visual Ergonomics Handbook focuses on vision and eye-care issues in both the office and industrial setting, including eye safety issues in industrial plants and construction sites. The text integrates the knowledge of leading experts in the fields of optometry, ergonomics, eye safety, and occupational medicine into a comprehensive, easy-to-read volume that also analyzes the economic benefits of developing a workplace visual ergonomics program. Written at a level that makes the information easily accessible, the chapter authors provide a simplified but thorough discussion of the process of eyesight and the components of the visual system. They explore the technology behind computer displays, discuss environmental issues surrounding eye symptoms and vision in the workplace, and examine lighting, glare, monitor position, vision distances, and other issues in detail. The chapter on glare in the workplace clarifies the role of anti-glare filters for display and the chapter on eye examinations covers the information that is critical to describe to the doctor. A discussion of the economic impact of ergonomic programs wraps up the main volume of the book. The book's multidisciplinary chapter authors give you wide ranging coverage of the issues and the editorial guidance of Jeffrey Anshel ensures that redundancies are weeded out. The first comprehensive handbook on visual ergonomics, it presents information that is adequately straightforward and technical.

A compact business education that strategically incorporates 500 keywords to lay the foundation and over 50 action items to initiate meaningful advances and excel in your eye care practice today. Medical training is a difficult journey with enormous amounts of information to absorb over a short time period. The intense time commitment required during this process leaves little opportunity to study any other discipline. However, even the most intelligent and well-intentioned provider cannot care for patients if the front door of the building is closed. Simply put: A fundamental background in business is required to effectively practice medicine. Eye care professionals, which includes their ophthalmic staff, can now fill the critical gap in their education with Essential Business Fundamentals for the Successful Eye Care Practice, providing them the necessary basic tools to make and execute winning practice management decisions. Writing in a high-density format that medical professionals will be familiar with, Dr. Savak Teymoorian combines his physician training and experience as a successful ophthalmologist at Harvard Eye Associates with the knowledge acquired earning his MBA. This unique perspective allows him to provide the proper theory and execution in the business of eye care and present it in an efficient manner like that used in medical education. Each chapter is dedicated to a different subject that would routinely be taught in a masters of business administration degree, tailored specifically for eye care professionals and distilled into the most critical information for a strong foundation. Each section is further enhanced with real life examples seen in ophthalmic care showing how to properly apply business strategies and tactics to obtain the best results. Chapter topics include: Marketing Leadership Negotiations Operations Finance Ophthalmologists, optometrists, and eye care staff will appreciate Essential Business Fundamentals for the Successful Eye Care Practice for its efficient and relevant information to running an eye care practice, whether they are currently in training and want to set themselves up for success or they are already practicing and want to fill in a deficiency in their knowledge.

A revision and reference text for pre-registration and postgraduate optometrists, covering procedures for investigating heterophoria, heterotropia, vergence and accommodative anomalies. The text covers the diagnosis of disorders of voluntary eye movement, nystagmus and supranuclear defects, paresis and non-paralytic incomitancy. Both motor and sensory anomalies are discussed together with syndromes involving oculomotor anomalies. Clinical management is outlined in protocols in an easily assimilable form. The second edition has additional information for final year undergraduates. Amblyopia treatment has been extended to cover new American optometric methods. Strabismus surgical techniques are now included. There are two new chapters on vision training and case management which will interest optometrists and orthoptists involved in sports vision and in developmental vision therapy. Pre-registration optometrists will find the chapters on routine orthoptic assessment and the PQE examination of particular interest.

This book has become an iconic textbook in eye care over many years and multiple editions having originally published in 1986. Considered one of the classic, definitive books for comprehensive anterior segment diagnosis, treatment, and management, this new edition includes a new chapter on pre- and postop management of cataract and refractive surgery and primary care of Glaucoma, which is a major part of primary care optometry today, along with updates on proprietary therapeutic drugs, and technology additions such as amniotic membranes, injectables, and minor in-office procedures. It contains high-quality photos, 6 clinical DX and RX appendices, an index of more than 1800 items, and 74 tables, making this an accessible resource for clinical practitioners. Key Features: * With a combined 130 years of clinical experience and expertise, the optometric authors provide succinct information necessary for diagnosing, treating, and managing all anterior segment, primary glaucoma, and non-surgical ocular conditions. * Includes current and new ocular, and systemic drugs along with pre & postoperative cataract and refractive surgery management protocols useful for clinicians to assist with diagnosis and treatment. * Features a unique presentation format as all the clinical (DX & RX) information is organized in the SOAP (Subjective, Objective, Assessment, Plan) format for quick referencing and practical use by the primary eye care practitioners.

Femtosecond-assisted laser in-situ keratomileusis flaps have revolutionized refractive surgery since their introduction. The use of the femtosecond laser to create the LASIK flap has led to an improvement in the safety profile of the flap creation step as compared to the mechanical microkeratome. Although this laser is exceedingly safe, complications still do occur. LASIK Emergencies: A Video Primer focuses specifically on the different flap complications that are still known to occur and their management. Designed as a narrated video-based book of ophthalmic surgeries, LASIK Emergencies covers the entire spectrum of Intralase flap complications. With 15 chapters, this book and accompanying website contains nearly 4 hours of state-of-the-art video teaching. Drs. Samir Melki and Ali Fadlallah have designed LASIK Emergencies so that each chapter focuses on a specific complication and its management, and features multiple videos for each. Each video is edited in such a way that the viewer can quickly grasp all the relevant information without having to sit through extensive, unedited surgical videos. Some Complications Covered: Loss of suction Air bubbles in the Anterior Chamber Irregular Flaps Subconjunctival hemorrhage and bleeding Ophthalmologists, laser ophthalmic technicians, and optometrists alike will appreciate this unique resource, as LASIK Emergencies: A Video Primer covers the entire spectrum of LASIK complications in a detailed, yet digestible manner.

This is the first book to cover all currently available methods to manage pre-, intra- and post-lacrimal sac stenosis. Comprehensive multidisciplinary approaches in adults and children are described. International experts provide a stepwise analysis and describe the clinical management of these patients with detailed medical and surgical treatment plans. With this guide's highly structured and reader-friendly format, the reader will be able to solve any problem that may occur with the reconstruction of a disturbed or damaged lacrimal system.

The key knowledge assembled in this book comprises today's most comprehensive resource on Sjoegren's syndrome. Sjoegren's patients require the care of a wide variety of clinical and surgical specialists to treat their disease and improve their quality of life. This volume presents a broad multi-disciplinary approach, enlisting the expertise of well-respected authors from around the world, covering the specialties of rheumatology, ophthalmology, oral medicine, oral surgery, otolaryngology, hematology, and others. This practical clinical resource begins with an overview of Sjoegren's myths, pearls and tips, information for referring physicians, and diagnostic and classification and criteria. The second section covers pathogenesis, providing the backbone for our understanding current diagnostics and therapeutics. The third section is devoted to clinical manifestations and therapeutic considerations. It covers the entire spectrum of symptoms and treatment, infused with the experience and astute clinical observations of the book's contributors. With system-wide coverage of local and systemic therapy, the book examines current therapy, biologics, and emerging therapeutic targets. Presenting many international perspectives, this book creates an inter-connective conduit for the global community of Sjoegren's patients and physicians.

This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye. It also highlights data obtained in various models from fish to human, as well as from the bionic eye project for vision regeneration. This volume in the Stem Cell Biology and Regenerative Medicine series is essential reading for stem cell biologists, ophthalmologists, advanced and graduate students, in addition to academics and medical staff who work in these disciplines.

Serves as an ideal complement to your medical student curriculum and a helpful tool for primary care residents and physicians who want to broaden their knowledge of eye disease diagnosis and treatment. The tenth edition includes updated, practical information on the diagnosis, management and referral of common ocular disorders, and summarises important ophthalmic concepts and techniques. It includes coverage of eye examinations, acute and chronic vision loss, red eye, ocular and orbital injuries, amblyopia and strabismus, neuro-ophthalmology, ocular manifestations of systemic diseases and drugs and the eye. This edition includes a new chapter on eyelid, orbital, and lacrimal disease. It also features 140 figures, access to 17 video clips, key points to remember, sample problems to test knowledge, and annotated resources.

This book will contain the proceedings of the XV International Symposium on Retinal Degeneration (RD2012). A majority of those who will speak and present posters at the meeting will contribute to this volume. The blinding diseases of inherited retinal degenerations have no treatments, and age-related macular degeneration has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 70. The RD Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them. Since most major scientists in the field of retinal degenerations attend the biennial RD Symposia, they are known by most as the "best" and "most important" meetings in the field. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy. While advances in these areas of retinal degenerations will be described, there will be many new topics that either were in their infancy or did not exist at the time of the last RD Symposium, RD2010. These include the role of inflammation and immunity, as well as other basic mechanisms, in age-related macular degeneration, several new aspects of gene therapy, and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those will be reported at the RD2010 meeting and included in the proposed volume. We anticipate the excitement of those working in the field and those afflicted with retinal degenerations will be reflected in the volume.

This handbook is designed to help shape the thought processes of the eye clinician or trainee and guide them toward the right decision-making pathway in emergency ophthalmology situations. Chapters are titled by the way cases present to eye casualty rather than condition, along with an algorithmic approach on what clinical and laboratory investigations to carry out. There is also guidance on how to perform simple procedures. It is aimed at trainees, general ophthalmologists and those with an interest from allied specialties (including specialist nurses) and professions such as optometrists and emergency medicine doctors. Key Features Stresses safe and practical navigation of common eye symptoms presented in an emergency setting. Provides guidance on differential diagnosis and includes useful decision-making flowcharts. Emphasizes "how to" approach the eye casualty patient. Shows what can be expected at each stage of the eye injury patient encounter. Presents information appropriate for the entire multi-disciplinary eye casualty team

The visual system must extract from the light that falls on the retina meaningful information about what is where in our environment. At an early stage it analyzes the incoming sensory data along many dimensions of pattern vision, e.g. spatial frequency, orientation, velocity, eye-of-origin. Visual Pattern Analyzers provides a definitive account of current knowledge about this stage of visual processing. Nowhere else can such a comprehensive summarty of the lower level pattern analyzers be found. The book's emphasis is on psychophysical experiments measuring the detection and identification of near-threshold patterns -- and the mathematical models, such as multidimensional signal-detection theory, used to draw inferences from such experimental results -- but neurophysiological evidence is presented and compared critically to the psychophysical evidence. Introductory material on psychophysical methods, signal detection theory, and the mathematics of Fourier analysis is given in order to make the book more accessible to all who are interested in the lower or higher levels of visual perception. This volume will be of great value to researchers and graduate students in the fields of vision and perception. Within the scientific community there is wide interest in the visual system, and the book will be of use to investigators in many fields, including psychophysics, neuroscience, ophthalmology and optics, computer science, and cognitive and experimental psychology.

Continuous regeneration of the cornea is necessary to maintain this tissue in the transparent state that is essential for vision. Therapy for repair of the damaged anterior cornea is currently addressed through the transplantation of donor corneas or the delivery of limbal epithelial stem cells (LESC) to the ocular surface using amniotic membrane (AM) as a supporting scaffold. Research on the bioengineering of corneal equivalents as replacement tissue is underway to develop viable corneal prosthetics. Corneal Regenerative Medicine: Methods and Protocols provides a concise overview of essential techniques in the field of corneal regenerative medicine, highlighting novel strategies to guide the management of key therapies within this area of medicine. Divided into four convenient sections, topics include the identification, characterisation and cultivation of LESC, as well as the investigation of biopolymers used as the basis for corneal substitutes. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Corneal Regenerative Medicine: Methods and Protocols covers the fundamental techniques useful for both the laboratory and clinical settings.

Daily rhythms are a ubiquitous feature of living systems. Generally, these rhythms are not just passive consequences of cyclic fluctuations in the environment, but instead originate within the organism. In mammals, including humans, the master pacemaker controlling 24-hour rhythms is localized in the suprachiasmatic nuclei of the hypothalamus (SCN). This circadian clock is responsible for the temporal organization of a wide variety of functions, ranging from sleep and food intake, to physiological measures such as body temperature, heart rate and hormone release. Moreover, accumulating evidence suggests that dysfunction of the circadian rhythms due to genetic mutations or environmental factors (i.e., jet-lag or shift work) contribute to the development of many pathologies, including sleep disorders, mood and affective disorders such as major depression, bipolar disorder and schizophrenia, as well as the risk of metabolic and cardiovascular disorders.

Neurointervention in the Medical Specialties is a first-of-its-kind reference that serves as a bridge between the neurointerventionalist and the physicians who most frequently look to these specialists for answers to some of the most intractable problems they face. Providing background on the wide range of diseases treated through neurointervention along with the indications and alternatives to such treatments, this landmark title is grouped into four parts: an introduction to the tools and anatomical structures that are integral to the field; disease processes most often encountered by neurologists, cardiologists, and vascular surgeons; those diseases more frequently treated by neurosurgeons; and finally those diseases first seen by several other specialties including ophthalmologists and head and neck surgeons. Importantly, each chapter includes details of neurointerventional technique and case discussions that are sufficiently detailed to provide a treatment template and guidance to neurointerventionalists in training and practice. At the same time, the descriptions provide referring physicians with insight into how neurointerventional procedures are performed. Finally, there are several concluding, thought-provoking chapters that examine what new opportunities await the field of neurointervention on the horizon. Neurointervention in the Medical Specialties is a major contribution to the literature and invaluable resource for all clinicians and researchers interested in this exciting field.

Clinical Ophthalmic Genetics and Genomics provides an accessible, clinically-focused reference for the evolving field of Genetic Ophthalmology. This well-organised, easy-to-read textbook integrates key concepts with clinical practice and is designed to enhance effective learning and retention of complex material. It includes contributions from recognised leaders in the field and provides expert guidance on the complete spectrum of genetic ophthalmic disorders.

The introduction of anti-vascular endothelial growth factor (VEGF) agents has revolutionized therapy for a host of ocular diseases associated with leakage from normal blood vessels and pathologic blood vessel growth. Anti-VEGF Use in Ophthalmology is an all-inclusive reference designed to provide detailed, up-to-date, and clinically relevant information on the current use of anti-VEGF agents in the treatment of all ocular conditions. Drs. Jay S. Duker and Michelle C. Liang have assembled a prestigious group of contributors who pool their collective expertise in this comprehensive book. Anti-VEGF Use in Ophthalmology is split into two sections with the first providing the history of VEGF and an overview of anti-VEGF agents and different routes of drug delivery, as it is important for eye care providers to be familiar with up-to-date aspects of the medications and indications for use. The second section details the clinical uses of anti-VEGF agents in numerous ocular diseases, from the anterior segment including cornea and glaucoma to uveitis and various retinal and choroidal diseases. Each chapter in this section summarizes the disease process and utilizes high-quality ocular imaging to demonstrate the therapeutic use of the anti-VEGF agents. Some of the topics covered in Anti-VEGF Use in Ophthalmology: Neovascular Age-Related Macular Degeneration Proliferative Diabetic Retinopathy Retinal Vein Occlusion Uveitis Neovascular Glaucoma Macular Edema Retinopathy of Prematurity Corneal Disease Anti-VEGF Use in Ophthalmology combines the theory and applications of anti-VEGF agents, making it not only a great learning tool for beginners but also a useful reference tool for a wide range of eye care professionals including optometrists, residents, comprehensive ophthalmologists, as well as specialists in anterior segment, pediatrics, and vitreoretinal disease.

The Duke Elder Exam of Ophthalmology - A Comprehensive Guide for Success is an indispensable resource for any student wishing to achieve the highest mark on the Duke Elder Exam and receive a prize. With expert knowledge of students and doctors that have scored high on the exam, along with the supervision of well-regarded ophthalmologists and trainees, we believe this is the only resource you will need to achieve a high score on the exam. Key Features In-depth coverage of the Duke Elder Curriculum including the basic sciences, anatomy, optics and all subspecialties of ophthalmology Full colour and easy to read with clinical photographs and diagrams to aid in the understanding of key topics 180 SBAs, which accurately reflect the format and difficulty of the exam

Photopigments are molecules that react to light and mediate a number of processes and behaviours in animals. Visual pigments housed within the photoreceptors of the eye, such as the rods and cones in vertebrates are the best known, however, visual pigments are increasingly being found in other tissues, including other retinal cells, the skin and the brain. Other closely related molecules from the G protein family, such as melanopsin mediate light driven processes including circadian rhythmicity and pupil constriction. This Volume examines the enormous diversity of visual pigments and traces the evolution of these G protein coupled receptors in both invertebrates and vertebrates in the context of the visual and non-visual demands dictated by a species' ecological niche.

All aspects of ophthalmic trauma from the lid to the optic nerve of both mechanical and nonmechanical trauma are covered in this unique book. The focus is on practical issues and incorporates cutting-edge approaches, such as temporary keratosprosthesis, artificial iris diaphragm, and prophylactic retinectomy.

This book explains and answers not simply the when, the what, and the how, but also the why questions. The information is based on epidemiologic and clinical data from evaluation to management.

All chapters are written using the standardized ocular traumatology terminology. The user-friendly format, including many tables, flowcharts and illustrations, allows the reader to quickly find the information they are looking for.

Written by a well-known expert in the field, this concise pocketbook provides clinically useful information that will be of great help to the attending ophthalmologists and emergency room physicians in the decision-making process. The book has practical recommendations for all who see patients with eye injuries."

This book, besides reviewing basic and clinical aspects of Behcet's disease, covers the latest findings, including genetic studies and treatment with biologics for the disease. Although the cause of Behcet's disease is still unknown, it is well known that genetic factors, such as HLA-B51, are involved in its development. Recently, novel susceptibility loci including IL10, IL23R-IL12RB2, and endoplasmic reticulum aminopeptidase 1 have been identified, providing new insights into the pathogenesis of the disease. In addition to basic research, the beneficial efficacy of anti-TNF-alpha monoclonal antibodies has also been suggested for not only uveitis associated with the disease but also other subtypes of the disease such as entero-, vasculo-, and neuro- Behcet's disease. Behcet's Disease: From Genetics to Therapies provides essential information both for basic researchers working in the fields of immunology, inflammation, and genetics, and for clinical physicians who are interested in Behcet's disease, such as ophthalmologists, rheumatologists, dermatologists, gastroenterologists, neurologists, and vascular surgeons.