1. Features recent developments like 3-D surgery, telescopic IOL, bionic implants and robotic surgery. 2. Highlights case selection and important precautions to be taken by vitreoretinal surgeons and senior residents. 3. Covers the controversies surrounding primary VR versus RD surgery in Phakic, fresh retinal detachments; Positioning after macular hole/ VR surgery; and to peel or not peel ILM in non-macular hole retinal surgery.

The book presents the most common problems seen in neuro-ophthalmology in a case-based learning format that provides rapid access and is easy to read. The user friendly format guides and stimulates the reader to identify the distinctive symptoms in the main complaint and history; to define the differentiating signs on neuro-ophthalmic exam; and to describe the key laboratory or neuroimaging in specific entities. It also challenges the reader to ask additional questions of themselves and others by providing an initial set of questions and answers on specific neuro-ophthalmologic topics.The questions chosen are meant to simulate "real world" questions in the clinic; the answers given serve to provide both the rationale for the correct answer and the explanations or reasons for the incorrect but plausible answers that might distract or mislead a clinician in specific neuro-ophthalmic cases.

Many of the studies discussed in this book were addition to discussions of a variety of hormonal, presented at the First Pan American Congress of biochemical, immunological, physical, and me Andrology, which was held in Caracas, Venezuela, chanical approaches. It is our hope that the efforts in March 1979. An international group of in of the contributors will help to intensify research vestigators have contributed reviews designed to and development of improved methods for safely be informative to medical, graduate, and post regulating male fertility. graduate students, as well as clinicians and in vestigators working in the area of male reproduc G. R. CUNNINGHAM tion. Current physiological concepts that may W. B. SCHILL provide insight for new initiatives are examined in E. S. E. HAFEZ TABLE OF CONTENTS Preface v Contributors IX Foreword by C. SCHIRREN XI 1. PHYSIOLOGY OF MALE REPRODUCTION 1. Hormonal regulation of testicular function 5 P. FRANCHIMONT 2. Inhibin: new gonadal hormone 15 P. FRANCHIMONT, A. DEMOULIN, J. VERSTRAELEN-PROYARD, M. T. HAZEE-HAGELSTEIN, and J. P. BOURGUIGNON 3. Morphological features of the epididymis: possible significance in male contraception 25 T. D. GLOVER 4. Regulatory physiology of male accessory organs 35 E. S. E. HAFEZ and G. R. CUNNINGHAM 5. Methods for evaluating contraceptive techniques 41 T. Z. HOMONNAI and F. G. PAZ II. HORMONAL CONTRACEPTION 6. Inhibition of male reproductive processes with an LH-RH agonist 55 A. CORBIN and F. J. BEX 7."

Intravitreal injections (injections into the eye) are a new form of treatment for various conditions such as age-related macular degeneration, diabetic eye disease and vascular eye problems. The use of these injections has become so widespread that most departments around the world (and particularly in the U.K) do not have enough doctors to meet the service provision demands of an ever increasing number of patients. Many departments have trialed training ophthalmic nurse practitioners as a solution and the number of such specifically trained nurses is set to rise exponentially in the future. This book is meant to be an easy to carry A5 handbook detailing all that an ophthalmic nurse practitioner needs to know about performing the procedure. It is hoped that the book will also be of benefit to trainee ophthalmologists learning the procedure.As this is an emerging area of expertise in ophthalmology, currently there exists no other books on the topic. The readers will benefit from having a single resource detailing all that they need to know about the procedure. This means that nurses will not have to cross reference multiple complicated ophthalmic textbooks. As an A5 handbook, it will be easy to carry and reference in clinics. It is deliberately meant to be concise (around 100 pages), thus concentrating only on the core knowledge required.

Digital fundus images can effectively diagnose glaucoma and diabetes retinopathy, while infrared imaging can show changes in the vascular tissues. Likening the eye to the conventional camera, Image Analysis and Modeling in Ophthalmology explores the application of advanced image processing in ocular imaging. This book considers how images can be used to effectively diagnose ophthalmologic problems. It introduces multi-modality image processing algorithms as a means for analyzing subtle changes in the eye. It details eye imaging, textural imaging, and modeling, and highlights specific imaging and modeling techniques. The book covers the detection of diabetes retinopathy, glaucoma, anterior segment eye abnormalities, instruments on detection of glaucoma, and development of human eye models using computational fluid dynamics and heat transfer principles to predict inner temperatures of the eye from its surface temperature. It presents an ultrasound biomicroscopy (UBM) system for anterior chamber angle imaging and proposes an automated anterior segment eye disease classification system that can be used for early disease diagnosis and treatment management. It focuses on the segmentation of the blood vessels in high-resolution retinal images and describes the integration of the image processing methodologies in a web-based framework aimed at retinal analysis. The authors introduce the A-Levelset algorithm, explore the ARGALI system to calculate the cup-to-disc ratio (CDR), and describe the Singapore Eye Vessel Assessment (SIVA) system, a holistic tool which brings together various technologies from image processing and artificial intelligence to construct vascular models from retinal images. The text furnishes the working principles of mechanical and optical instruments for the diagnosis and healthcare administration of glaucoma, reviews state-of-the-art CDR calculation detail, and discusses the existing methods and databases. Image Analysis and Modeling in Ophthalmology includes the latest research development in the field of eye modeling and the multi-modality image processing techniques in ocular imaging. It addresses the differences, performance measures, advantages and disadvantages of various approaches, and provides extensive reviews on related fields.

Ocular Surface Disease: Cornea, Conjunctiva and Tear Film incorporates current research and the latest management strategies as well as classification systems and treatment paradigms for all forms of ocular surface disease. This is the first comprehensive resource that helps you to meet ocular surface disease challenges effectively using today's best medical and surgical approaches. Get the complete, evidence-based guidance you need to provide optimal care for your patients with ocular surface disease. Implement the latest drug treatments and surgical interventions to provide better outcomes with fewer complications. Hone and expand your surgical skills by watching videos of leading experts performing advanced procedures including ocular surface transplantation techniques; amniotic membrane transplantation; pterygium surgery; lamellar keratoplasty (DALK) in ocular surface disease; and keratoprosthesis surgery. Visualize how to proceed by reviewing detailed, full-color images and consulting new classification systems and treatment paradigms for mild to severe forms of ocular surface disease. Take it with you anywhere! Access the full text, downloadable image library, video clips, and more online at expertconsult.com.

This book provides the first general and unified theory of visual discomfort. Based on the author's observation that people find certain visual stimuli uncomfortable--and that these same stimuli induce seizures in patients with photosensitive epilepsy--the book offers fascinating insights into a variety of visual stresses that arise from design, reading, lighting, television, and VDU terminals. A range of techniques for preventing and treating visual discomfort--from color therapy to precision tinting of spectacle lenses--are described in detail. Students and researchers in perceptual psychology, visual science, neurology, and optometry will want to read this pioneering new work.

Contains the proceedings of the XVI International Symposium on Retinal Degeneration (RD2014), to be held July 13-18, 2014 at the Asilomar Conference Center in Pacific Grove, California. A majority of those who will speak and present posters at the meeting will contribute to this volume. The Symposium addresses the blinding diseases of inherited retinal degenerations, which have no effective treatments and age-related macular degeneration, which has no cures, despite the fact that it is an epidemic among the elderly, with 1 in 3-4 affected by the age of 75. The RD2014 Symposium will focus on the exciting new developments aimed at understanding these diseases and providing therapies for them. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy; and several sight restoration approaches, including optogenetics. While advances in these areas of retinal degenerations will be included, several new topics either were in their infancy or did not exist at the time of the last RD Symposium, RD2012. These include many new developments in sight restoration using optogenetics, retinal or RPE cell transplantation, stem cell approaches and visual prosthetic devices. In addition, major advances will be presented in other basic mechanisms in age-related macular degeneration, several new aspects of gene and antioxidant therapy and revolutionary new imaging and functional testing that will have a huge impact on the diagnosis and following the course of retinal degenerations, as well as to provide new quantitative endpoints for clinical trials. The retina is an approachable part of the central nervous system (CNS), and there is a major interest in neuroprotective and gene therapy for CNS diseases and neurodegenerations, in general. It should be noted that with successful and exciting initial clinical trials in neuroprotective and gene therapy, including the restoration of sight in blind children, the retinal degeneration therapies are leading the way towards new therapeutic measures for neurodegenerations of the CNS. Many of the successes recently reported in these areas of retinal degeneration sprang from collaborations established at previous RD Symposia, and many of those will be reported at the RD2014 meeting and included.

Basic and Clinical Applications of Vision Sciences contains the edited papers presented at the Enoch Vision Science Symposium, April 27-30 1996, which was organized in honor of the pioneer in vision science, Dr Jay M Enoch. Dr Enoch served for twelve years as Dean, School of Optometry, University of California, Berkeley. The book is organized along the lines of Dr. Enoch's contributions to vision science, but is not limited to these topics. Of special note, the reader will find papers on important new developments in photoreceptor, ophthalmic and visual optics, retinal imaging, ophthalmic physiology and pathophysiology, visual psychophysics and visual techniques. The papers are grouped into the following sections: photoreceptor optics; ophthalmic and visual optics; binocular vision, developmental vision, eye movements and physiology; ophthalmic dysfunction; visual psychophysics and clinical applications; history of vision science. GBP/LISTGBP

Extensively revised, this state-of-the-art 3rd edition of Cataract Surgery offers new perspectives and cutting-edge coverage of the rapidly evolving field of cataract surgery. Roger F. Steinert, MD, along with a who's who of top international experts, delivers comprehensive clinical coverage of the latest surgical techniques, principles, and pearls, as well as expert advice on preoperative assessment and how to avoid and manage complications. Detailed discussions on today's hot topics such as aspheric and presbyopia IOL, phacoemulsification, and more, keep you at the forefront of this burgeoning field. And, more than 1050 illustrations and a DVD containing videos of cataract procedures give you step-by-step visual guidance. Plus, with Expert Consult functionality, you'll have easy access to the full text online at www.expertconsult.com. Features expert tips on common pitfalls in cataract surgery, including advanced surgical pearls to maximize patient outcomes. Contains 10 new chapters covering Modular Intraocular Lenses (IOLs), Femtosecond-Laser-Assisted Cataract Surgery, Preoperative Evaluation and Considerations of Astigmatism, Toric Intraocular Lenses (IOLs), Managing Residual Postoperative Astigmatism, Retinal Considerations in Cataract Surgery, Management of Dysphotopsia, Refractive Enhancements after Cataract Surgery, and more. Provides rich visual guidance with more than 1,200 diagnostic, clinical, and surgical photos and illustrations with clear explanations. Includes more than 50 videos of narrated surgical footage performed by the authors, offering real-time guidance on the full range of the latest cataract surgery techniques. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Provides access to the full-text online at www.expertconsult.com for convenient referencing. Includes a DVD of surgical videos performed by the authors, offering you real-time guidance on the full range of the latest cataract surgery techniques, including phacoemulsification in the presence of a small pupil, toric IOL implantation, biaxial microincision cataract surgery, and many others. Features expert hints and tips on the common pitfalls in cataract surgery, including advanced surgical pearls to save you valuable time and help you avoid costly errors. Offers expanded coverage on how to manage complications, to prepare you for the challenges you face. Provides the latest information on phacoemulsification techniques, keeping you on the cusp of these popular procedures. Presents new chapters on Aspheric Multifocal, Accommodating IOLs, Color-filtering IOL, IOL design, and Capsular opacification offering you the latest information in this rapidly advancing area.

A sound knowledge of basic sciences is vital for any doctor with an interest in ophthalmology, and is a significant part of all postgraduate examinations in the subject. Featuring 640 multiple choice questions, this is a comprehensive revision guide for candidates taking the basic sciences component of the FRCOphth and ICO examinations. It is highly recommended for ophthalmologists of all grades, ranging from juniors completing ICO basic sciences and FRCOphth examinations to seniors wishing to refresh their knowledge and revalidate. This book is divided into relevant chapters with topics that follow logically, offering a thorough approach to revision and exam practice. Each chapter includes questions in both the FRCOphth (SBA) and ICO (true or false) formats. Detailed, referenced answers are provided to aid comprehension, with difficulty levels allocated for each question to gauge personal progress.

The Macula, Aging and Macular Degeneration: Lipofuscin in Aged and AMD Eyes (C.D. Dorey et al.). Retinoid Reaction Products in AgeRelated Retinal Degeneration (G.E. Eldred). Retinitis Pigmentosa and Allied Retinal Degenerations: Heterogeneity of Usher Syndrome Type I (R. Ayyagari et al.). Studies Toward the Isolation of the RP3 Gene (A.F. Roux et al.). Studies of Retinal Degeneration Using Transgenic Mice and Other Animal Models: Creating Transgenic Mouse Models of Photoreceptor Degeneration Caused by Mutations in the Rhodopsin Gene (F. Wong). Systematic Alterations in Docosahexaenoic Acid Metabolism in Inherited Retinal Degenerations (N.G. Bazan et al.). Agents Which Cause or Prevent Retinal Degeneration: Growth Factors as Possible Therapeutic Agents for Retinal Degeneration (M.M. LaVail et al.). The Effect of Naphthalene on the Retina of Rabbit (N. Orzalesi et al.). 27 additional articles. Index.

Mycotic keratitis, also known asfungal keratitis, is commonly defined as an inflammation of the cornea. Globally, mycotic keratitis is more common as compared to others eye disorders. Though it occurs in all parts of the world it is more prevalent in tropical and subtropical areas. Mycotic Keratitis emphasizes novel perspectives on mycotic keratitis treatments and addresses different therapies used in treatment. The book is designed to be immensely useful for the students and teachers of microbiology, medicine, mycology, ophthalmology, biotechnology and nanotechnology. Medical microbiology researchers in general and medical mycology in particular will find it a valuable user-friendly book.

Ocular Surface, Lids, Tears: The Evolution of Lid Margin Changes in Blepharitis; A.J. Bron, J.M. Tiffany. Corneal Transplantation and Eye Banking: Stromal Hydrodelamination Technique in Deep Lamellar Keratoplasty with Complete Removal of Pathologic Stroma; J.Sugita. Corneal Stroma and Endothelium: An Update on Corneal Hydration Control; J. Fischbarg, D.M. Maurice. Refractive Surgery I: Corneal Tattooing to Treat Glare Symptoms Following Radial Keratotomy; G.J. Florakis et al. Molecular Biology, Cellular Biology, and Genetics: Wound Healing Modulators in Tear Fluid T. Tervo, M. Vesaluoma. Contact Lenses: The Effect of Contact Lenses on the Conjunctiva P.C. Donshik. Microbial Keratitis-Viral: The Biology and Pathology of Varicella Zoster Virus in the Ganglion; T.J. Liesegang. Keratoconus: The Case for Eye Rubbing as the Major Cause of Keratoconus; J.H. Krachmer. Non-Microbial Keratitis and Immunology: Abstracts of Conference Presentations. World Corneal Health: Childhood Keratitis: Epidemiological and Microbiological Study; A. Panda et al. Microbial Keratitis-Non-Viral: Refractive Surgery II: 38 additional articles. Index.

This book addresses diabetic retinopathy, an eye disease that remains one of the main causes of vision loss if not diagnosed and managed properly. It aims to cover the entire spectrum of the disease by describing its clinical identification and characterization, pathophysiology, epidemiology, and medical and surgical management. Diabetic Retinopathy also offers a complete overview of the present understanding of diabetic retinopathy, covering current practice but also including original contributions that offer novel perspectives for looking at and addressing this disease.

The author has dedicated his lifetime to the study of diabetic retinal disease and has organized this book around his personal experience but at the same time giving the necessary information for updated management of diabetic retinopathy. Diabetic Retinopathy will be especially useful for postgraduate students in diabetology, retina specialists and researchers.

Elizabeth Rakcozy and a team of leading clinical and experimental scientists describe in step-by-step detail the key techniques essential to effective molecular biological research in ophthalmology and optometry. These readily reproducible methods are adapted to the special requirements of vision research, with coverage that ranges from the most basic to the most sophisticated technologies. Included are methods for the down-regulation of gene expression, new gene therapy techniques, and for the development of transgenic and knockout animal models for testing novel therapies. Eminently accessible and clinically relevant, Vision Research Protocols provides experimental and biomedical investigators in ophthalmology and optometry with a rich panoply of most powerful tools with which to ask--and answer--all the important questions emerging from the dramatically advancing work in vision research today.

The management of emergent neuro-ophthalmic conditions can be a life-saving encounter for the general ophthalmologist. This book covers life-threatening scenarios that a general ophthalmologist might encounter, and is designed to help the ophthalmologist make emergency triage decisions for initial evaluation and treatment of potentially vision- or life-threatening conditions. This book is case based, and provides the reader with the invaluable expert views of two neuro-ophthalmologists. One, Dr Lee is an ophthalmology-based neuro-ophthalmologist and the other, Dr Brazis is a neurology-based neuro-ophthalmologist. Dr Mughal and Dr Policeni collected and collated the case vignettes during their fellowship with Dr Lee at the University of Iowa Hospitals and Clinics. This textbook provides a concise, easy to read, and practical guide to the emergent evaluation of neuro-ophthalmic conditions. It is designed to be a quick read and not to be all-inclusive or comprehensive. The reader is directed to longer and more comprehensive neuro-ophthalmic texts for this information. It is also not the aim of the book to provide information on anatomy, pharmacology, physiology, or other basic mechanisms of disease. Instead, this text is meant to be a quick reference and resource for the clinician in the emergency room or in the clinic facing a potentially vision- or life-threatening emergency and to provide immediate guidance for potentially "high stakes" decision making. The case vignettes are based upon real clinical cases but the clinical details of each case have been modified for teaching purposes and represent composite rather than individual histories.

This book is a comprehensive treatise on infective and inflammatory pathologies of the cornea with corresponding clinical images and diagrammatic illustrations. Corneal infections and inflammations are a major cause of ocular morbidity and visual impairment. Early diagnosis and treatment can lead to improved visual outcome and quality of life. Both infectious (bacterial, fungal, viral and protozoan) and non-infectious keratitis that cause corneal vascularisation, scarring and vision loss are covered extensively. The illustrated clinical findings presented in the form of diagrams, photographs, cases and videos aim to serve as a practical teaching tool for fellows, trainees and practising ophthalmologists. KEY FEATURES Focuses on clinically relevant parts of corneal diseases, using illustrations with arrows indicating different pathologies and signs Serves as a ready clinical compendium for trainees, fellows and ophthalmologists Explores various corneal pathologies through a wealth of accompanying illustrations and teaching videos

Myopia is the most common optical disorder in the world, and is on the rise in many countries, particularly in East Asia. The impact of myopia is evident as the driving force in the development of refractive surgery and of the spectacle and contact lens industries. While myopia is often seen as a childhood disease that involves complex genetic-environmental factors, it is also a major cause of adult blindness. In Singapore (where myopia has reached one of the highest rates in the world) as well as in Taiwan, Japan and Hong Kong, affected patients have greater severity of myopia, leading to additional secondary complications such as glaucoma.This book provides a comprehensive coverage of all aspects of myopia. It is aimed at ophthalmologists, optometrists, opticians, scientists and pharmaceutical companies. The topics are uniquely treated in that they cover research at the laboratory bench as well as clinical applications and population-based approaches in epidemiology.

Neuro-ophthalmology, like in any field of medicine, has many areas where controversy exists in diagnosis and treatment. Controversies in Neuro-Ophthalmology provides a comprehensive overview on the clinical presentation, diagnosis, and management of neuro-ophthalmic disorders and specifically addresses areas where there is a general lack of consensus amongst practitioners. Each chapter opens with a case to illustrate a pertinent controversy and then poses a clinical question. The issue is then discussed by world leading experts to provide a balanced viewpoint. Designed to foster vigorous debate among colleagues, this book is essential reading for neuro-ophthalmologists, ophthalmologists, and neurologists.

Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss of the axons making up the optic nerve. Recent studies have demonstrated support for the classification of glaucoma as a degenerative disease of the central nervous system (CNS). The search for treatment modalities that are effective for all patients with glaucoma has resulted in numerous studies aimed at identifying neuroprotection strategies for the treatment of this disease, like those used for other degenerative diseases of the CNS.
The present book will provide an in-depth examination of the most recent findings regarding glaucoma, including risk factors, diagnosis, clinical monitoring, treatment, and above all, the need for treatment based on the concept of neuroprotection. A large part of the book is devoted to research related to this new approach to the treatment of glaucoma. Aspects that will be analyzed include experimental models of glaucoma, clinical protocols for the study of neuroprotective therapies, mechanisms underlying glaucomatous damage to neurons of the retina and other "stations" in the visual pathways of the CNS, and finally proposals for new strategies for preventing neuronal injury in glaucoma patients.
* Describes the most recent developments on neuroprotection of the optic nerve, including experimental models now used and clinical protocols
* Discusses new strategies for the prevention of neuronal injury in glaucoma patients
* Focuses on evidence-based risk factors, innovative diagnostic aspects and advanced medical/surgical treatment of glaucoma

Phillips and Ruth Thygeson were pioneers in medical research on external diseases of the human eye. Together, this husband-and-wife team shared a mutual story of extraordinary accomplishment including, among other things, the discovery of the cause and the cure of trachoma, a potentially blinding disease that affects millions of people worldwide.This comprehensive biography tells the complete story of their personal lives and careers. Beginning with each of their childhoods, the story continues through their meeting on the campus of Stanford University, their years of practicing ""frontier medicine"" in rural Colorado (where they built a log cabin with their own hands), their world travels in search of a cure for trachoma, and their considerable roles in establishing the Francis I. Proctor Foundation for Research in Ophthalmology. The story of this couple is one of a lifelong collaboration in medicine, a 70-year love affair, and an unending quest to conquer preventable blindness around the world.

Filling the need for a succinct, up-to-date guide in the management of sight-threatening disorders, this source provides a clear and practical approach to the treatment and analysis of posterior segment intraocular inflammatory conditions. Practical Manual of Intraocular Inflammation includes:

• full coverage of diagnosis, clinical assessment, and management of symptoms
• descriptions of external inflammatory conditions, as well as uveitis
• full-color algorithms, scientific charts, schematic illustrations, and clinical photographs

With over 60 color images, ophthalmologists, optometrists, and primary care physicians will find this source well-illustrated and documented, making this reference indispensable to any eye and vision practice.

Providing an ideal balance of theory and practice, Low Vision: Principles and Management covers all aspects of providing effective eye care to individuals with visual impairment. This concise yet comprehensive resource covers everything from theoretical background to current rehabilitative aids and low vision treatment strategies-all while adopting a practical approach to vision care. It brings practising eye care professionals and students fully up to date with current optical and electronic devices and how they are used in everyday practice, as well as evidence-based vision rehabilitation guidelines. Features comprehensive guidance on visual rehabilitation for acuity loss and visual field loss. Describes a wealth of practical advice and real-world case scenarios to help guide your day-to-day patient interactions as well as your most challenging situations. Covers hot topics, including the link between mental health and low vision, assistive technologies, measures of quality of life and other outcome measures, WHO classifications of visual impairment, and best practices for auditing and commissioning vision services. Contains over 200 diagrams, illustrations, and patient photos to aid in visual understanding. Explains how eye care professionals can work within a multi-disciplinary team to provide complete care. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.

Glaucoma surgery is difficult and fraught with complications. Some complications are common and mild, while others are rare and/or vision threatening. However, good outcomes are still likely if those complications encountered are managed properly. This book is intended for those surgeons wishing to improve their skills and abilities to manage difficult problems that will come up during the care of glaucoma patients. Comprising seven comprehensive sections, chapters in this volume address outflow mechanisms after glaucoma surgery, wound healing processes and modulators, complications in filtering surgery, tube shunt implantation, and angle procedures, among other topics. The authors of each chapter provide surgical and clinical pearls not only for managing difficulties but in preventing them as well. Additionally, because each surgeon has their own way of addressing a particular situation, there is commentary at the end of each chapter to provide another opinion or strategy for dealing with a particular surgical scenario. Cross-referencing is provided throughout this book to direct the reader to as many helpful sections as possible. Both thorough and highly-illustrative, this book will help both new and experienced glaucoma surgeons deal with complications and provide successful results for their patients.