This unique textbook is designed to provide a summary of state of the art developments in both male and female fertility and its association with cancer for both new and experienced practitioners. Clear, concise and readable, the text allows the reader to obtain rapid answers to this challenging medical issue. Special emphasis is placed on diagnostic and treatment algorithms. Topics covered include demographics of cancer in the reproductive age male, fertility conditions which predispose to cancer development, the role of assisted reproduction for fertility management, as well as fertility preservation strategies for the male and female cancer patients. Cancer and Fertility will be of great value to general urologists, uro-oncologists, gynecologists, medical oncologists, obstetricians, primary care providers, allied health providers.

For people who start losing their vision to macular degeneration, the prospect of impending blindness is frightening and terribly depressing. They often get contradictory advice about surgery, medical treatments, natural supplements, and lifestyle changes that might arrest or reverse the condition—and these conflicting recommendations only compound their anxiety. In this newly revised and updated second edition of Macular Degen - eration: A Complete Guide for Patients and Their Families, patients and their loved ones can turn to one easy-to-understand and authoritative source for up-to-date information about macular degeneration. Written by renowned ophthalmologist Michael Samuel, M.D., a retinal specialist, this book casts the spotlight on macular degeneration and dispels the myths surrounding this disease. This book offers a wealth of insights into what macular degeneration is, what causes it, and the array of contemporary treatment options. Here readers will learn: Lifestyle and environmental factors that can affect your risk of developing age-related macular degeneration (AMD). Dietary strategies to prevent or slow the progression. Nutritional supplements that work. The difference between dry AMD and wet AMD. When surgery is the best option. How to choose an eye-care professional. How to deal with the stress of vision loss Written for patients—and those who love and care for them—this book is the definitive source for information about macular degeneration; the tools, techniques, and strategies contemporary medicine offers people grappling with this illness; and the prospects for stopping, and even reversing, the progression of this disease.

This comprehensive and detailed text deals with the diagnosis and surgery of blepharoptosis, and will benefit any practicing physician, fellow or resident who deals with blepharoptosis.

Well organized and easy to read, Clinical Procedures in Primary Eye Care, 5th Edition, takes an accessible, step-by-step approach to describing the commonly used primary care procedures that facilitate accurate diagnosis and effective patient management. This practical, clinically-focused text offers succinct descriptions of today's most frequently encountered optometric techniques supported by research-based evidence. You'll find essential instructions for mastering the procedures you need to know, including recent technical advances in the field. Discusses technical advances that are dramatically altering optometry: Optical Coherence Tomography (OCT) and ultra-wide field imaging (optomaps). Presents outstanding new digital images of OCT cases and optomaps for a wide variety of conditions of the central and peripheral retina. Focuses on evidence-based optometry; all procedures include a section that reviews when and how the procedure should be measured and uses clinical wisdom in addition to research-based evidence. Presents new digital images of normal variations of the eye - crucial visual support for understanding what is normal and what is disease. Helps you clearly visualize procedures and eye disorders through full-color photographs, diagrams, and video clips. Provides fully revised print on dry eye assessment based on the latest international Dry Eye Workshop (DEWS) guidelines. Features coverage of changes in the eye due to high myopia, and expounds the need for myopia control techniques. Offers extensive material online to enhance learning: video clips, interactive testing sections, additional photographs, and more. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This is a reference text for both the novice and the accomplished ophthalmic surgeon. The book imparts basic information on tissue tactics and knot tying and demonstrates the applicability of these techniques to various microsurgical situations, in both the anterior and the posterior segment of the eye. Illustrated with photos and line drawings, each chapter contains sections on: Surgical indications, Instrumentation and equipment, Surgical technique, Complications and future challenges.

Head and neck pathology is increasingly becoming an attractive field for the new generations of pathologists, fully aware that in the era of specialization the information contained in the treatise of general surgical pathology, although extremely valuable to create the basis of their knowledge, does not provide in its full picture the specific knowledge required to meet current diagnostic and prognostic requirements. The book Pathology of the Head and Neck presents in a single volume the most pertinent and updated information needed by the interested readers. Its contents have been divided into ten chapters. The first one covers the spectrum of precursor and neoplastic lesions of the squamous epithelium. It is followed by chapters devoted to nasal cavities and paranasal sinuses, oral cavity, maxillofacial skeleton and teeth, salivary glands, nasopharynx and Waldeyers ring, larynx and hypopharynx, ear and temporal bone, neck and neck dissection, as well as eye and ocular adnexa. The authors of the different chapters have been selected among internationally recognized experts, all of them members of the Working Group on Head and Neck Pathology of the European Society of Pathology.

This book is the latest volume in the Recent Advances in Ophthalmology series providing ophthalmic trainees and ophthalmologists with the latest surgical and technological developments in the field. Divided into nineteen chapters, each section is dedicated to a specific topic, explaining symptoms, investigation techniques, imaging, differential diagnosis and treatment methods. The pros and cons of various surgical procedures are covered in depth. This new volume features discussion on types of refractive surgery, the latest endovascular interventions, infection control, new avenues for the treatment and progression of glaucoma and much more. The text includes two editorials covering imaging in glaucoma and intravascular interventions, and is highly illustrated with surgical images and tables. Key points Latest volume in Recent Advances in Ophthalmology series Covers latest surgical and technological developments in the field Features two editorials on imaging in glaucoma and intravascular interventions Previous volume (9789351527909) published in 2015

The new edition of this two-volume set is a complete guide to the eye, and the diagnosis and management of ocular diseases and disorders. Divided into 18 sections, the book begins with discussion on refraction, retinoscopy and low vision. The next section covers ocular genetics, gene editing, microbiology and pathology, then numerous different imaging techniques. Each of the following sections provides in depth coverage of different disorders and conditions that may occur in a specific part of the eye. A complete section is dedicated to clinical trials. The second edition has been fully revised and updated to provide clinicians with the latest advances in the field. Many new topics have also been added to this edition. The comprehensive text is highly illustrated with nearly 3500 clinical photographs, diagrams and tables across 3300 pages. Key points Comprehensive guide to complete field of ophthalmology over two volumes and 3300 pages Fully revised second edition providing latest advances and featuring many new topics Highly illustrated with nearly 3500 clinical photographs, diagrams and tables Previous edition (9789350252703) published in 2011

OCT is a relatively new imaging technique that is becoming increasingly popular among ophthalmologists in both private and academic settings. Imaging has been a slow moving area in ophthalmology for some time, but now OCT is providing another, more detailed source of demonstrable change in the eye, in diagnostic, therapeutic or post-surgical setting. OCT and ultrasound both measure advancing disease states and post surgical healing. The difference is that OCT shows more subtle changes, particularly post-surgically.

From the introduction: "The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 years on the physiology of intraocular pressure, ocular blood flow and the relation of these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the author's own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby led to new methods of diagnosis and therapy."

This book reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing radiation outside of the visible wavelengths. Comprehensive and penetrating, the book brings together the mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.

This book presents new and noteworthy research into retinal diseases. It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.

Vascular diseases of the retina are a major cause of blindness among all age groups. Edited and written by internationally well-known experts, this state-of-the-art comprehensive overview of basic and clinical science will enhance the understanding of retinal vascular disease and help in the evaluation of current and future treatment approaches for the clinician. The well-structured and highly illustrated text is divided into three easy-to-follow sections. This unique textbook-atlas also includes topics which are not currently found in other retinal disease textbooks, such as case reports and clinical follow-ups.

This lavishly illustrated atlas demonstrates normal in-vivo anatomy of the cornea, limbus, and conjunctiva; quantifies various cellular structures using cell-density calculations; and establishes correlations between novel optical sections of various diseases of the ocular surface and clinical findings. It also describes early signs of different eye diseases and supports the reader in diagnostic and therapeutic management.

This book covers all relevant techniques of diagnosis as well as interpretations of clinical signs in Clinical Neuro-Ophthalmology. All information is highly structured, highlighting 'definition', 'note' and 'pearl', so that it can also be used by the physician during the patient encounter. The included flow chart posters remind the physician of the most important information. This unique and practical guide offers invaluable and practical advice for physicians treating patients with neuro-ophthalmic problems.

Adequate blood supply to the eye is an important prerequisite for normal visual function. Over the past 40 years our knowledge of ocular blood flow regulation has improved significantly. This reader-friendly textbook provides a comprehensive overview of the current knowledge of ocular blood flow. Lavishly illustrated, it evaluates the wide array of methods that have been used to measure ocular blood flow. Furthermore, it not only offers the reader an evidence-based summary of the physiological and pharmacological properties of ocular blood flow regulation, but also demonstrates the ocular blood flow abnormalities in different vascular diseases. This book will enhance the understanding of all who are interested in learning more about ocular blood flow in health and disease.

Digital retinal imaging performed by primary care providers and nurses, followed by remote image interpretation (teleretinal imaging), is rapidly acquiring a crucial role in many parts of the world as it permits the detection of major diseases, such as diabetic retinopathy and glaucoma, in patients who would otherwise be beyond the reach of a trained ophthalmologist. In this book, experts from around the world describe how digital teleretinal screening can be set up and optimally utilized. Technical issues are discussed, and the appropriate use of screening for different diseases and in different age groups is explained. The major part of the book draws upon the clinical experience of leading practitioners in a wide range of teleretinal applications. The result is a comprehensive source of high-quality information for clinicians and other health professionals who are involved in eye care delivery, so that they can assess how teleretinal screening might be applied to their working practice.

Basic Sciences in Ophthalmology aims to link clinical ophthalmology directly to its basic science roots. This first volume describes the physics and chemistry required for a sound understanding of modern ophthalmology. The book opens with an extensive discussion of the interaction of light with matter and the way in which light is used in ophthalmic examinations and treatments. After describing traditional methods of imaging, particular emphasis is placed on modern instrumentation such as OCT. The interaction between light and tissues in different types of laser treatment is also addressed. The chemistry section focuses on compounds particularly relevant to the eye, such as oxygen and water. The origin and consequences of oxidative stress are reviewed, and the physical behavior of chemical compounds in the eye is explained. Understanding is facilitated through the use of many examples taken from the field of ophthalmology. The text is complemented by about 450 figures.

1 The physical and chemical fundamentals of fluorescence angiography 2 The technical fundamentals of fluorescein angiography 3 Normal Fluorescence Angiography and General Pathological Fluorescence Phenomena 4 Fundus Autofluorescence 5 Macular Disorders 6 Retinal Vascular Disease 7 Inflammatory Retinal/Choroidal Disease 8 Optic Neuropathies 9 Intraocular Tumors

This book serves as an introductory reference on clinical aspects of glaucoma and myopia, providing essential guidelines for diagnosis and monitoring of glaucoma progression in patients, especially those with high myopias. Many clinical studies are presented by leading experts in the field in an accessible style, making the content suitable not only for ophthalmologists but also for optometrists and certified orthoptists as well as for students. The relation between myopia and glaucoma has been the subject of many clinical trials and population-based studies. Most of the data has suggested that moderate to high myopia is associated with increased risk of primary open-angle glaucoma, normal tension glaucoma, and ocular hypertension. There are several factors involved in the diagnosis of glaucoma, but it is often difficult to determine the presence of glaucoma in myopic eyes. A myopic eye, especially in cases of moderate to high myopia, tends to have a thin retina and choroid and to appear thinner than normal. Even with new imaging technologies with improved sensitivity and specificity for detecting glaucoma, each technology presents some challenges when assessing myopic eyes. This book furnishes an overview of these diagnostic challenges with reference to the growing prevalence and severity of myopia in various parts of the world, providing many valuable hands-on reports and clinical studies by authoritative authors. This knowledge will help to do away with the vague area between high myopia and glaucoma faced by clinicians.

Written by global experts in the field of chemical- and drug-related ocular problems, Drug-Induced Ocular Side Effects, 8th Edition, provides need-to-know information on all aspects of ocular toxicology in one concise reference. This best-selling, user-friendly resource features a templated format, numerous full-color illustrations, and sweeping content updates throughout - all designed to eliminate uncertainty and ensure accurate diagnosis and treatment guidance. Provides comprehensive coverage of drugs' generic and trade names, primary uses, ocular and systemic side effects, and clinical significance. Features a unique side effect index, a new concise paperback format for portability, and clinical photos of ocular symptoms of adverse drug reactions. Covers dozens of new drugs used in the U.S. and internationally, as well as extensive updates to drug registry information to ensure access to the latest data. Includes expanded sections on how to follow patients with visual adverse drug reactions to chloroquine, hydroxychloroquine, isotretinoin, ethambutol, and more. Guidelines can be copied to use as patient handouts. Offers extensive discussions of principles of therapy, ocular drug delivery, methods to evaluate drug-induced visual side effects, and the role of electrophysiology and psychophysics. Provides the WHO classification system to help you determine whether a particular side effect is certain, probable, or likely to occur. Ideal for ophthalmologists, optometrists, and busy clinicians in primary care, emergency medicine, and more - anyone who needs quick, on-the-spot consultation on ocular toxicology. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Written as a practical guide for the diagnosis and treatment of uveitis, this text provides uveitis specialists, practicing ophthalmologists, ophthalmology residents and fellows with the appropriate diagnostic testing and evidenced-based therapeutic options for managing patients afflicted with these conditions. Written and edited by leaders in the fields of ophthalmology, rheumatology, internal medicine, infectious disease, and oncology, each chapter addresses the latest advances in the field: from the advent of PCR technology, intraocular depot steroid implants, neoplastic and infectious diseases masquerading as uveitis, and the use of systemic immunomoduatory therapies (including biologic agents/humanized monoclonal antibodies).

Midfacial Rejuvenation is a comprehensive review of the majority of procedures and options for midfacial aesthetic and corrective surgery. Each contributor offers a unique approach to the midfacial area, with detailed specifics for every technique. Chapters on midfacial anatomy, complications and their management complete the comprehensive coverage of the subject matter, resulting in a reference text that will benefit every practitioner dealing with the midfacial region. Features: * One of the first books to focus exclusively on the midfacial area * Highly illustrated and with clear, step-by-step instructions on performing a variety of midface lifts, implants, sutures, grafts, and fillers * Over 300 full color images * Includes in-depth chapters on midfacial anatomy and the anatomic basis of aging * Multiple approaches to midfacial rejuvenation by well-known surgeons in fields such as oculoplastics, facial plastics, general plastics, and dermatologists

Textbook of Laser Refractive Cataract Surgery is a comprehensive reference for the general ophthalmologist and cataract surgeon regarding the explosive new technology in femtosecond laser cataract surgery. Femtosecond laser allows extreme precision in surgery, and is used in refractive surgery and for 'cuts' in the cornea, leading to a more uniform treatment for the patient. Textbook of Laser Refractive Cataract Surgery is for cataract surgeons and all eye care providers managing or diagnosing cataracts who wish to be informed about this technology and its applications. Edited and written by recognized leaders in the field, this book covers background, technical, clinical, and commercial aspects of this exciting technology. Some of the topics covered include the evolution of cataract surgery, femtosecond laser fundamentals, challenges of femtosecond laser technology for cataract surgery, and the economics of laser cataract surgery. Edited and written by recognized leaders in the field, this book covers background, technical, clinical, and commercial aspects of this exciting technology. Some of the topics covered include the evolution of cataract surgery, femtosecond laser fundamentals, challenges of femtosecond laser technology for cataract surgery, and the economics of laser cataract surgery.

Basic Science Underlying Retinal Degeneration.- Analysis of Genes Differentially Expressed During Retinal Degeneration in Three Mouse Models.- Regulation of Angiogenesis by Macrophages.- Protein Kinase C Regulates Rod Photoreceptor Differentiation Through Modulation of STAT3 Signaling.- Pigment Epithelium-derived Factor Receptor (PEDF-R): A Plasma Membrane-linked Phospholipase with PEDF Binding Affinity.- The Function of Oligomerization-Incompetent RDS in Rods.- The Association Between Telomere Length and Sensitivity to Apoptosis of HUVEC.- Photoreceptor Guanylate Cyclases and cGMP Phosphodiesterases in Zebrafish.- RDS in Cones Does Not Interact with the Beta Subunit of the Cyclic Nucleotide Gated Channel.- Increased Expression of TGF-?1 and Smad 4 on Oxygen-Induced Retinopathy in Neonatal Mice.- ZBED4, A Novel Retinal Protein Expressed in Cones and Muller Cells.- Tubby-Like Protein 1 (Tulp1) Is Required for Normal Photoreceptor Synaptic Development.- Growth-Associated Protein43 (GAP43) Is a Biochemical Marker for the Whole Period of Fish Optic Nerve Regeneration.- Multiprotein Complexes of Retinitis Pigmentosa GTPase Regulator (RPGR), a Ciliary Protein Mutated in X-Linked Retinitis Pigmentosa (XLRP).- Misfolded Proteins and Retinal Dystrophies.- Neural Retina and MerTK-Independent Apical Polarity of ?v?5 Integrin Receptors in the Retinal Pigment Epithelium.- Mertk in Daily Retinal Phagocytosis: A History in the Making.- The Interphotoreceptor Retinoid Binding (IRBP) Is Essential for Normal Retinoid Processing in Cone Photoreceptors.- Aseptic Injury to Epithelial Cells Alters Cell Surface Complement Regulation in a Tissue Specific Fashion.- Role of Metalloproteases in Retinal Degeneration Induced by Violet and Blue Light.- Mitochondrial Decay and Impairment of Antioxidant Defenses in Aging RPE Cells.- Ciliary Transport of Opsin.- Effect of Hesperidin on Expression of Inducible Nitric Oxide Synthase in Cultured Rabbit Retinal Pigment Epithelial Cells.- Profiling MicroRNAs Differentially Expressed in Rabbit Retina.- Unexpected Transcriptional Activity of the Human VMD2 Promoter in Retinal Development.- Microarray Analysis of Hyperoxia Stressed Mouse Retina: Differential Gene Expression in the Inferior and Superior Region.- Photoreceptor Sensory Cilia and Inherited Retinal Degeneration.- Role of Elovl4 Protein in the Biosynthesis of Docosahexaenoic Acid.- Molecular Genetics and Candidate Genes.- Molecular Pathogenesis of Achromatopsia Associated with Mutations in the Cone Cyclic Nucleotide-Gated Channel CNGA3 Subunit.- Mutation Spectra in Autosomal Dominant and Recessive Retinitis Pigmentosa in Northern Sweden.- 1 Rhodopsin Mutations in Congenital Night Blindness.- GCAP1 Mutations Associated with Autosomal Dominant Cone Dystrophy.- Genotypic Analysis of X-linked Retinoschisis in Western Australia.- Mutation Frequency of IMPDH1 Gene of Han Population in Ganzhou City.- Diagnostic, Clinical, Cytopathological and Physiologic Aspects of Retinal Degeneration.- Reversible and Size-Selective Opening of the Inner Blood-Retina Barrier: A Novel Therapeutic Strategy.- Spectral Domain Optical Coherence Tomography and Adaptive Optics: Imaging Photoreceptor Layer Morphology to Interpret Preclinical Phenotypes.- Pharmacological Manipulation of Rhodopsin Retinitis Pigmentosa.- Targeted High-Throughput DNA Sequencing for Gene Discovery in Retinitis Pigmentosa.- Advances in Imaging of Stargardt Disease.- Protamine Sulfate Downregulates Vascular Endothelial Growth Factor (VEGF) Expression and Inhibits VEGF and Its Receptor Binding in Vitro.- Computer-Assisted Semi-Quantitative Analysis of Mouse Choroidal Density.- Thioredoxins 1 and 2 Protect Retinal Ganglion Cells from Pharmacologically Induced Oxidative Stress, Optic Nerve Transection and Ocular Hypertension.- Near-Infrared Light Protect the Photoreceptor from Light-Induced Damage in Rats.- BDNF Improves the Efficacy ERG Amplitude Maintenance by Transplantation of Retinal Stem Cells in RCS Rats.-