Advances in the study and understanding of myasthenia gravis have led to the need for the publication of this important new edition. The goal of Myasthenia Gravis and Related Disorders, Second Edition is identical to the first -- to provide the clinician and the scientist with a common resource for understanding this complex disorder. This new edition begins with discussions of neuromuscular junction structure and function and follows with updated chapters covering a wide range of topics, such as the acetylcholine receptor, clinical presentation, diagnostic evaluation, and treatment. Importantly, new supplemental chapters have been added; these discuss rigorous clinical assessments of patients for research trials and the epidemiology and genetics of myasthenia gravis. The discussion of the most challenging aspects of myasthenia gravis, its impact on patients psychological make-up, has been expanded as well. Myasthenia Gravis and Related Disorders, Second Edition retains the personal approach of the authors regarding treatment and is a valuable resource for meeting the many and varied needs of patients with myasthenia gravis."

It is with great pleasure that I write this Foreword to the Proceedings of the International Conference on Behcet's Disease which was held in Berlin in June 2002. This was the first International Conference held under the auspices of the International Society for Behcet's Disease which was founded in 2000 in Seoul. First, I congratulate our colleagues in Berlin, led by Professor Christos Zouboulis of the Department of Dermatology at the Free University of Berlin, for having organised a most successful conference and for having compiled these proceedings so rapidly. It will be realised immediately on scanning the contents of this book that the conference was truly international with 210 participants from 26 countries, as Professor Zouboulis has noted in his preface. These included basic scientists, epidemiologists, pathologists, clinicians and, importantly, representatives from patient organisations. The latter held their own conference alongside the scientific-medical conference to mutual benefit. The combined session of patients and doctors (abstracts on pp 601 - 626) gave the opportunity for an exchange of information and fruitful discussion. The wide ranging scope of the communications is evident from the index and it was most encouraging to see their origin - from all parts of the world, from senior and junior colleagues and, from many different disciplines. Many communications may be regarded as preliminary reports of research in progress and we look forward to seeing the definitive publications in appropriate journals in due course."

This third volume of "Uveitis and Immunological Disorders" in Essentials in Ophthalmology provides up-to-date, relevant information for the reader. Our knowledge and understanding of immune mechanisms has increased exponentially over the past few years and has expanded to disorders such as diabetic retinopathy and macular degeneration. This volume will provide the ophthalmologist with practical information on how to diagnose and treat these difficult, and in some cases, blinding disorders. In addition, there are important discussions of the mechanisms underlying these conditions, which incorporate the most recent, up-to-date research material available. "Summary for the Clinician" and "Core Messages" sections enhance the value of each chapter. This volume was written by authors who are leaders in their field. Important and provocative questions dealing with recent developments are raised. Topics covered include:

Matching in Penetrating Keratoplasty

Acute Anterior Uveitis and HLA-B27: What's new?

What can the aqueous humour tell us about Uveitis?

Is Diabetic Retinopathy an inflammatory disease ?

Steroid sensivity in Uveitis

Multiple Sclerosis and Uveitis

Inflammation in Age-related Macular Degeneration: what is the evidence?

Immunological factors in Age-related Macular Degeneration: what is the consequence ?

Patterns of Retinal Vascular Involvement in the diagnosis of Retinal Vasculitis

Masquerade syndromes

This highly practical and clinically relevant volume is valuable to all those involved in the handling and treatment of patients with ocular inflammation. In addition, it provides fresh perspectives and insights into our current understanding of common disorders such as diabetic retinopathy and macular degeneration.

A comprehensive survey on the use of bedside skills and perimetric devices to the test visual fields, and how to interpret the results. To develop the clinician's interpretative skills, the authors include a chapter on visual anatomy and an atlas of 100 real-life cases arranged in anatomic order from retina to striate cortex. By placing a brief clinical vignette with a visual field on one side of the page and a description of the field and its causal lesion on the opposite side, the reader will be able to learn interpretation in a simulated clinical setting. An additional quiz section of twenty randomly arranged visual fields provides readers with an opportunity to test their newly acquired skills.

Progress in vitreo-retinal surgery is mercurial. Since this series is dedicated to new developments the reader is presented with a motley list of topics. The advancements described here may represent generally accepted progress in the field: New instruments, Macular hole surgery, Tumor biopsy. New ideas are set out to be tested for their benefit, for example: AMD surgery, Adjunctive pharmacotherapy. Reflections on incessant clinical problems in vitreo-retina surgery require superior scrutinization of established surgical techniques and indications: Posterior slippage, Inferior breaks, Subclinical retinal detachments. The editors will expand this list in future editions with topics like: new support for buckling surgery, enzyme assisted vitrectomy, new tamponades and other yet unknown fields of progress.

Sensory Neuroscience: Four Laws of Psychophysics organizes part of psychophysics -- a science of quantitative relationships between human sensations and the stimuli that evoke them. Although psychophysics belongs to sensory neuroscience, and is coupled to neurophysiology, it has also branched out to various specialized disciplines, including the disciplines of vision and hearing, ophthalmology, optometry, otology, and audiology. Due to this diversification and fragmentation, psychophysics has had an ad-hoc, phenomenological orientation. Besides Weber's law of differential sensitivity, and the still-controversial Stevens' power law, it has lacked a systematic grid of scientific laws. Sensory Neuroscience: Four Laws of Psychophysics provides valid unifying principles and systematic applications for this otherwise fragmented precursor of experimental psychology, and defines four multisensory relationships of substantial generality between sensations and the underlying stimulus variables. This book will be particularly useful to auditory researchers, experimental psychologists, and behavioral neuroscientists.

Among the many intense light sources, excimer lasers have a unique set of properties that place them at the forefront of tooling for material processing. Their extreme versatility means that they can be used in many areas of materials science and medicine. But three conditions need to be fulfilled in order that their versatility be truly appreciated and exploited: the characteristics and limitations of the sources must be known; the basic excimer laser processes should become reasonably widely known; and problems in search of a solution should be clearly identified. Excimer Lasers covers all three of these points in an instructive and logical way. Probably for the first time, both instrumental and fundamental aspects of excimer laser interaction with matter are presented side-by-side, with examples drawn from the widest range of materials. The articles gathered here are tutorial in their nature, thus making them suitable for a wide readership, from recent graduates and postgraduate students to those established scientists entering the field, all of whom could not find a better, nor more authoritative work with which to start their reading.

Some of the best vision scientists in the world in their respective fields have contributed to chapters in this book. They have expertise in a wide variety of fields, including bioengineering, basic and clinical visual science, medicine, neurophysiology, optometry, and psychology. Their combined efforts have resulted in a high quality book that covers modeling and quantitative analysis of optical, neurosensory, oculomotor, perceptual and clinical systems. It includes only those techniques and models that have such fundamentally strong physiological, control system, and perceptual bases that they will serve as foundations for models and analysis techniques in the future. The book is aimed first towards seniors and beginning graduate students in biomedical engineering, neurophysiology, optometry, and psychology, who will gain a broad understanding of quantitative analysis of the visual system. In addition, it has sufficient depth in each area to be useful as an updated reference and tutorial for graduate and post-doctoral students, as well as general vision scientists.

This outstanding volume in the Essentials in Ophthalmology series presents recent developments in the diagnosis and treatment of corneal disease. Its intention is not to replace the relevant textbooks, but to serve as a bridge between primary and tertiary literature. The superbly structured volume covers a dizzying array of topics including Herpes simplex keratitis; amniotic membrane transplantation for the treatment of corneal ulceration in infectious keratitis; and Chlamydial infection, all three of which are hugely relevant today. All the topics have direct clinical importance and will not only keep ophthalmologists up to date, but will inform them of how to treat their cornea patients with optimal diagnostic and therapeutic procedures.

This volume discusses the background and various clinical applications of radiation therapy in the treatment of non-malignant diseases. It documents the radiobiological and physical principles of treatment and the rationale underlying the use of radiotherapy for various disorders of the CNS, head and neck, eye, skin and soft tissues, bone and joints, and vascular system. In so doing, it draws attention to and elucidates the scope for application of radiotherapy beyond the treatment of malignancies. Both the risks and the benefits of such treatment are fully considered, the former ranging from minor clinical problems to life-threatening diseases.

For more than 30 years, the visual cortex has been the source of new theories and ideas about how the brain processes information. The visual cortex is easily accessible through a variety of recording and imagining techniques and allows mapping of high level behavior relatively directly to neural mechanisms. Understanding the computations in the visual cortex is therefore an important step toward a general theory of computational brain theory.

Aimed at students taking a course on visual perception, this textbook considers what it means for a man, a monkey and a computer to perceive the world. After an introduction and a discussion of methods, the book deals with how the environment produces a physical effect, how the resulting "image" is processed by the brain or by computer algorithms in order to produce a perception of "something out there." It also discusses color, form, motion, distance, and also the sensing of three dimensionality, before dealing with visual perception and its role in awareness and consciousness. The book concludes with discussions of perceptual development, blindness, and visual disorders. Visual perception is by its very nature an interdisciplinary subject that requires a basic understanding of a range of topics from diverse fields, and this is a very readable guide to all students whether they come from a neuroscience, psychology, cognitive science, robotics, or philosophy background.

With the rapid advancement of corneal topography and wavefront technologies and the increased application of corneal topography not only in refractive but also in premium IOL surgery, a new edition of the best-selling Corneal Topography: A Guide for Clinical Application in the Wavefront Era will be the foremost resource for both ophthalmologists and optometrists. In this Second Edition, Dr. Ming Wang, Dr. Tracy Swartz and over 50 contributors combine the important topics of refractive and premium lens surgeries and put corneal topography in the context of wavefront technology. With over 500 images, this edition gives special attention to the latest advances in these technologies. The state-of-the-art science and application of corneal topography for these anterior segment surgeries is well represented in Corneal Topography, A Guide for Clinical Application in the Wavefront Era, Second Edition, making it the latest and most comprehensive reference of these state-of-the-art technologies for refractive and for premium IOL surgery. Topographic and Wavefront Technologies Covered Include: * Placido disc-based topographic systems * Elevation-based topographic systems * Ultrasound-based topographic systems * OCT-based topographic systems * Topography and wavefront combined systems Topographic Applications Covered Include: * Topographies of corneal diseases, including post-RK/CK/LASIK/PRK * Topography-guided contact lens fitting * Topography application in refractive surgery and in premium IOL surgeries * Topographic guidance for corneal surgeries * Topography-guided custom treatments * Combined treatment strategies using topography and wavefront data * Future development of corneal topography in the wavefront era Updated and reorganized to reflect changes in the technology, Corneal Topography: A Guide for Clinical Application in the Wavefront Era, Second Edition is indispensible for all anterior segment surgeons, ophthalmologists, and

Tis book is more than an atlas and a text. It has what clinicians Professor Sundmacher communicates with clarity, continuity want most: experience. and style. Actual case examples are analyzed by a specialist who has Te book's strength is in its details. Terapeutic decisi- arguably treated more patients with ocular herpes than any making is based on clinical research, ofen the author's own other ophthalmologist. Not merely an inventory of viral kera- pioneering trials. For medical and surgical dilemmas, practi- titis, this sourcebook explains the ins and outs of infection and based advice springs from a pragmatic explanation of virology, infammation due to herpes simplex virus, varicella-zoster vi- immunology and wound healing. rus and other herpes viruses. Te profciency and scope of this authoritative resource Herpetic eye disease needs a descriptive vocabulary, and leads me to rephrase a century-old maxim: 'To know herpes is the author provides a sensible classifcation. His distinctive to know ophthalmology.' terminology updates outmoded jargon, creating a new norm.

All aspects of ophthalmic trauma from the lid to the optic nerve of both mechanical and nonmechanical trauma are covered in this unique book. The focus is on practical issues and incorporates cutting-edge approaches, such as temporary keratosprosthesis, artificial iris diaphragm, and prophylactic retinectomy.

This book explains and answers not simply the when, the what, and the how, but also the why questions. The information is based on epidemiologic and clinical data from evaluation to management.

All chapters are written using the standardized ocular traumatology terminology. The user-friendly format, including many tables, flowcharts and illustrations, allows the reader to quickly find the information they are looking for.

Written by a well-known expert in the field, this concise pocketbook provides clinically useful information that will be of great help to the attending ophthalmologists and emergency room physicians in the decision-making process. The book has practical recommendations for all who see patients with eye injuries."

Ophthalmic microsurgery is applied in ophthalmic pathological conditions. Ophthalmic pathology sets the landmarks for all kinds of microsurgical manipulations. Thus, in order to ensure the best surgical outcome, ophthalmic clinicians and microsurgeons have to consider the critical structures and potential complications before they start with the surgical procedure.

Written by the world famous expert G. O. H. Naumann, this excellent textbook emphasizes the ocular structures such as the nuances of morphology, surgical anatomy, and pathology.

The content includes: Unique features of closed system intraocular surgery in closed system and open eye surgery.- Crucial aspects of restoring the anterior chamber, includes such as the role of blood-ocular barriers and effects of paracenthesis-effects. The spectrum of potential complications in (pseudo-) exfoliation- syndromes as well as the most vulnerable cell populations.- The features of normal and pathologic wound healing in the various tissues after non-mechanical laser and mechanical interventions emergency-pathology requiring prompt surgical intervention.

Brilliant artwork and sketches are further illustrating and summarizing the complex pathology. Thus, the reader will derive great value for the daily routine when learning how the specific pathology modifies the indications and techniques of microsurgery.

This lavishly illustrated unique atlas provides a comprehensive and up-to-date overview of FAF imaging in retinal diseases. It also compares FAF findings with other imaging techniques such as fundus photograph, fluorescein- and ICG angiography as well as optical coherence tomography.

General ophthalmologists as well as retina specialists will find this a very useful guide which illustrates typical FAF characteristics of various retinal diseases.

Simplified Facial Rejuvenation is divided into sections that include anatomy and anesthesia, classifications, dermatologic procedures, suture lifts, surgical variations of the face, surgical variations of the eyes, brow, neck, lips, nose ear, and scalp, and medical legal aspects. The book presents multiple variations of suture lift procedures to allow the physician to decide which is best. Unique surgical procedures of the face are presented, many of which are techniques of minimal incision facelift. The book brings together the more popular procedures for patients that include simpler methods of facial rejuvenation with less pain, shorter recovery time, lower cost, and fewer complications.

LASIK: The Evolution of Refractive Surgery takes you on a journey through the latest in laser and wavefront technology, as well as the most recent surgical procedures that include various complex cases, complications, and management. Dr. Lucio Buratto is joined by Drs. Stephen Slade and Marco Tavolato, along with a team of 23 world-renowned surgeons, to produce a complete book specifically designed to improve the patient's quality of vision with LASIK. All surgeons will benefit from the format in which basic surgical procedures are explained, as well embracing the latest information available such as advanced laser procedures with ablations, femtocecond lasers, and excimers. With more than 250 color illustrations demonstrating the various procedures and concepts, the book will help ophthalmologists develop a more thorough understanding of LASIK. LASIK: The Evolution of Refractive Surgery is perfect for the surgeon interested in learning the concepts, developing the skills, and preparing for the surgical procedure. LASIK: The Evolution of Refractive Surgery contains a detailed description of the basic technique of LASIK and the special techniques devised by Dr. Lucio Buratto, Dr. Slade, Dr. Tavolato, and a group of highly acclaimed international surgeons experienced with encountering standard and unusual circumstances. LASIK: The Evolution of Refractive Surgery will provide the multitude of LASIK techniques that have emerged and the technological advancements that have made them possible and is a necessary text for all surgeons aspiring to improve their surgical results using the latest techniques available today.

Modern laser vision correction has continually changed since its inception. The evolution of this procedure has been aided by broad technological advancements, increased surgical knowledge, and increased understanding of the cornea and its response to lasers. PRK: The Past, Present, and Future of Surface Ablation will provide a complete vision of the PRK laser correction techniques that have emerged and the technological advancements that have made them possible. The collaboration of Drs. Buratto, Slade, Serrao, and Lombardo, along with a team of international surgeons have produced a complete book specifically designed to assist clinician's to improve the quality of their patient's vision. With over 85 color illustrations demonstrating the various procedures and concepts, the book will help ophthalmologists develop a more thorough understanding of PRK. PRK: The Past, Present, and Future of Surface Ablation is excellent for surgeons interested in learning the concepts, developing skills, and preparing for the actual laser procedure. This definitive resource couples both the authors' and 9 contributors' diverse experience and knowledge to produce a complete vision of PRK laser vision correction. PRK: The Past, Present, and Future of Surface Ablation will be the definitive resource necessary for all surgeons aspiring to improve their surgical results using the latest techniques available.

Pterygium surgery often presents a challenge to ophthalmic surgeons due to a high tendency for tissue re-growth. Pterygium: Techniques and Technologies for Surgical Success details the latest advances in ocular surface surgery, as well as new methods to overcome the traditional complications of pterygium surgery. Dr. John A. Hovanesian and his contributors address pterygium surgery through a detailed compilation of intraoperative and postoperative patient management. Pterygium: Techniques and Technologies for Surgical Success includes step-by-step details on a wide range of treatment therapies, such as: * Use of fibrin tissue adhesive * Conjunctival autograft techniques, including wide margin autograft * Amniotic membrane techniques and pearls * Mitomycin and 5FU Adjuncts * Conjunctival Chalasis * Postoperative complications management, including the surgical approach to recurrences Pterygium: Techniques and Technologies for Surgical Success is an indispensible resource for ophthalmic surgeons, residents, fellows, and assisting staff who must keep up with the latest ocular procedures regarding pterygium surgery.

In our world of information overload, there is an increasing struggle to keep the main thing the main thing. Fundamental OSCE Guide in Ophthalmology is a concise study guide presented in a direct, exam style question and answer format, illustrated with high quality clinically relevant photographs tailored to medical students, nurses, optometrists and residents in their early ophthalmology training.This book provides invaluable guidance to readers in presenting their answers in a logical, succinct and elegant manner. The style and format have been intentionally designed to simulate examination conditions and to provide readers with ample practice in preparation for the examinations.Ophthalmology is a very specialized field with many textbooks providing a wealth of information. Exposure to ophthalmology is limited in most undergraduate interactions to a few weeks at best. With a shortage of time, gaining a good understanding of what is important is overwhelming. This book helps to streamline and focus knowledge of readers in understanding the essential conditions in ophthalmology.Various other texts on ophthalmology are often in prose and covers a wide range of topics, including the esoteric conditions. To the untrained eye, it is difficult to discern what should be focused on. Students are often times excited about knowing rare conditions and spend precious time and effort remembering details of these conditions without a strong foundation of the more common conditions seen day to day. This books not only highlights the important conditions, it is structured to simulate examination conditions and can be used as a self-testing tool.

"Essentials in Ophthalmology" is a new review series covering all of ophthalmology categorized in eight subspecialties. It will be published quarterly, thus each subspecialty will be reviewed biannually.
Given the multiplicity of medical publications already available, why is a new series needed? Consider that the half-life of medical knowledge is estimated to be around 5 years. Moreover, it can be as long as 8 years between the first description of a medical innovation in a peer-reviewed scientific journal and publication in a medical textbook. A series that narrows this time span between journal and textbook would provide a more rapid and efficient transfer of medical knowledge into clinical practice, and enhance care of our patients.

Series:

Highly practical and clinically relevant

Ophthalmology series is indispensable for continuous education and advanced training

All editors with international reputation and contributing authors with expertise in their topics

Reader-friendly format: Well-structured text and design, quick and easy to read

Richly illustrated with numerous tables and color photos

Bridges the gap between primary literature and daily practice

Every 2nd year each subject is refreshed with timely information about the new development in the specialized field

This volume:

Appeals not only to Ophthalmologists, but also to Pediatricians

Gives quick and practical introduction to the most up-to date treatment options in pediatric ophthalmology

Only addresses new developments of the past 2 years

Covers 3 main topics: Genetics, Pediatrics and Neurophthalmology, while competing titles focus on one of these subspecialties

"

IOL Power by Kenneth J. Hoffer, MD will be the definitive resource worldwide for ophthalmologists who strive to increase the accuracy for all IOL calculations,especially for multifocal IOLs and overcoming the challenges that arise when treating patients that have had laser refractive surgery, such as RK, PRK, LASIK, and LASEK. Inside the pages of IOL Power, Dr. Hoffer is joined by some of the most respected international physicians and physicists in the field of IOL power such as Aramberri, Haigis, Norrby, Olsen and Shammas. Together their expertise, spanning over 35 years, makes even the most difficult subjects easy to understand. This volume will become the definitive reference source on the subject of IOL power calculation. Some topics include: * Ultrasound velocities for axial length measurement * Optical AL (IOLMaster and Lenstar) in difficult eyes * Manual and automatic keratometry and instrumentation * Topography & Scheimpflug camera corneal power * Value of theoretic formulas * Formula personalization * Multifocal and toric IOLs * Aspheric IOLs * Effect of IOL tilt on astigmatism Chapters Cover: * All aspects of obtaining the most accurate biometry * Available modern calculation formulas * Latest instruments * Problems that can arise, how to prevent and repair them IOL Power by Kenneth J. Hoffer, MD is structured in a logical manner so as to cover every facet of IOL power from the basics to the most complicated subjects to achieve the most accurate and precise calculations and should be in the hands of all ophthalmic surgeons, technicians, residents and students.