Although monotherapy is generally recommended as the treatment of choice, treatment resistance of patients with psychosis, cognitive, mood and anxiety disorders represents a significant clinical problem. In this context, augmentation and combination strategies are commonly employed to address this problem. Although multiple medication use common in psychiatric practice, reasons, efficacy and safety for polypharmacy, and augmentative strategies have remained unclear. It remains unclear if there is an evidence base to support polypharmacy. Furthermore, excessive and inappropriate use of psychotropic medications has been recognized as a public health problem. This volume is the first comprehensive, clinically oriented, reference on the multiple medication use to treat psychotic, cognitive, mood and anxiety disorders.

This volume reviews the known neurobiology of depression and combines classic data on antidepressant treatments with modern theory on the physiology of depression. It also discusses novel mechanism of action drugs.

This book presents an integrative, dualist model of mental disorder for psychiatry, as a counter to the so-called "biomedical" approach that dominates the field today. Starting with the humanist concept that mental disorder is real, it uses a computational approach to build a genuinely bio-psycho-social model. This shows that mental disorder is primarily psychological in nature, not biological. The historical background extends as far as Descartes, and proceeds via some of the revolutionary thinkers who have shaped modern society. In particular, it builds on the work of George Boole, Alan Turing and Claude Shannon to construct a radically new concept of the mind as a real, informational space which, for better off for worse, can malfunction. It extends this idea to build models of personality, of personality disorder, and then of mental disorder. Finally, the concepts are tested against a variety of themes from other fields to show its generality. Based in the philosophy of science and of mind, this work represents a radical departure from anything in the history of psychiatry. Its purpose is to provide a formal, articulated model of mental disorder to fill the theoretical void at the core of modern psychiatry. This book is written for medical students and recent graduates, for psychiatrists, psychologists, social workers and, broadly, anybody with an interest in human affairs, such as philosophy, politics and other related fields.

This book explores how Circles of Support and Accountability can reduce sexual reoffending. The release of a notorious sex offender from prison strikes fear into members of the public. Media coverage often provokes further panic, casting such offenders as irredeemable monsters and ticking time bombs, destined to continue preying on innocent children and women. In the West, governments have responded by enacting heavily punitive and exclusionary policies, such as public sex offender registers, indefinite detention, and lifetime correctional supervision. A radically different approach - Circles of Support and Accountability (CoSA) - emerged alongside these measures. CoSA are groups of trained volunteers who collectively resist the exclusionary impulse, instead actively supporting those with sexual offence convictions to reintegrate into communities. Despite their seemingly counterintuitive nature, the research is clear that CoSA reduce sexual reoffending far better than more popular draconian sex offender management policies. However, little is understood about how CoSA work. This book begins to address this gap by proposing a new way of understanding how CoSA reduce sexual reoffending. Drawing on 65 in-depth interviews with CoSA participants, it offers a new theoretically-informed empirical explanation of CoSA's capacity to promote desistance from sexual offending, and to turn those convicted of sexual offenders into law-abiding and productive members of the community. Ultimately it is a call to action, demonstrating that we, the community, must play a more central role in integrating people with sexual offence convictions if we desire safer communities for our children and our selves. This work illuminates new directions for research, policy, and practice, and is essential reading for academics and students engaged in the study of criminology and criminal justice, restorative justice, sexual violence, and reentry

Global contributors and IPA connection could ensure large geographic market. Potential readership could include a huge spectrum of health workers, as well as psychiatrists. Little work has been done on the subject - fills a niche.

Drawing on the pioneering work of Janet, Freud, Sullivan, and Fairbairn and making extensive use of recent literature, Elizabeth Howell develops a comprehensive model of the dissociative mind. Dissociation, for her, suffuses everyday life; it is a relationally structured survival strategy that arises out of the mind's need to allow interaction with frightening but still urgently needed others. For therapists dissociated self-states are among the everyday fare of clinical work and gain expression in dreams, projective identifications, and enactments. Pathological dissociation, on the other hand, results when the psyche is overwhelmed by trauma and signals the collapse of relationality and an addictive clinging to dissociative solutions. Howell examines the relationship of segregated models of attachment, disorganized attachment, mentalization, and defensive exclusion to dissociative processes in general and to particular kinds of dissociative solutions. Enactments are reframed as unconscious procedural ways of being with others that often result in segregated systems of attachment. Clinical phenomena associated with splitting are assigned to a model of "attachment-based dissociation" in which alternating dissociated self-states develop along an axis of relational trauma. Later chapters of the book examine dissociation in relation to pathological narcissism; the creation and reproduction of gender; and psychopathy. Elegant in conception, thoughtful in tone, broad and deep in clinical applications, Howell takes the reader from neurophysiology to attachment theory to the clinical remediation of trauma states to the reality of evil. It provides a masterful overview of a literature that extends forward to the writings of Bromberg, Stern, Ryle, and others. The capstone of contemporary understandings of dissociation in relation to development and psychopathology, The Dissociative Mind will be an adventure and an education for its many clinical readers.

A Clinician's Guide to Gender Actualization provides an essential guide for mental health professionals working with gender diverse clients, delivering material that challenges clinicians to provide affirming specialized care for their clients. Gender actualization is the social, expressive, and existential process of becoming and integrating one's authentic self through the context of gender identity, and this book introduces an effective clinical model for competent gender therapy care. Building upon the reader's foundational knowledge, chapters provide useful assessment tools, interventions, and treatment strategies to implement in their clinical practice, with accompanying personal narratives and client experiences woven throughout. Challenging readers to explore intersectionality and the crucial awareness of their own privileges, this book is a critical read for providers working with or seeking to educate themselves regarding gender diverse clients.

A Clinician's Guide to Gender Actualization provides an essential guide for mental health professionals working with gender diverse clients, delivering material that challenges clinicians to provide affirming specialized care for their clients. Gender actualization is the social, expressive, and existential process of becoming and integrating one's authentic self through the context of gender identity, and this book introduces an effective clinical model for competent gender therapy care. Building upon the reader's foundational knowledge, chapters provide useful assessment tools, interventions, and treatment strategies to implement in their clinical practice, with accompanying personal narratives and client experiences woven throughout. Challenging readers to explore intersectionality and the crucial awareness of their own privileges, this book is a critical read for providers working with or seeking to educate themselves regarding gender diverse clients.

Global contributors and IPA connection could ensure large geographic market. Potential readership could include a huge spectrum of health workers, as well as psychiatrists. Little work has been done on the subject - fills a niche.

Transcultural Cognitive Behaviour Therapy for Anxiety and Depression is a practical and accessible guide, drawing on current research in CBT and clinical practice. It aims to support therapists in taking a reflective and evidence based approach to genuinely improving access and outcomes for Black and Minority Ethnic service users. It highlights the skills that clinicians need to undertake Culturally Adapted and Culturally Sensitive CBT and provides practical ideas and case examples that will enable therapists to feel confident in adapting models of assessment and treatment across cultures. The emphasis of this book is on practical clinical techniques and approaches but it is firmly grounded in the research literature on this topic. Therapists, supervisors and service leads will find useful ideas to support and enrich transcultural working and develop their confidence when applying evidence based interventions across cultures. Transcultural Cognitive Behaviour Therapy for Anxiety and Depression will be of interest to Improving Access to Psychological Therapies (IAPT) trained cognitive behaviour therapists, clinical psychologists and cognitive behaviour therapists. The book will also appeal to those undertaking advanced or postgraduate studies in CBT.

Integrative Therapies for Depression: Redefining Models for Assessment, Treatment and Prevention summarizes emerging theories and research findings on various nonpharmaceutical therapies to treat mood disorders. Supported by the review of nearly 3000 scientific studies, the book describes the concepts of inflammation, genetics, hormonal imbalance, gastrointestinal conditions, environmental stress, and nutritional deficiencies and their possible link to the pathogenesis of mood disorders. It also examines findings on various nonpharmaceutical therapies used to treat mood disorders including vitamins, botanicals, and other natural products as well as exercise, stress reduction, bright light, mind-body practices, and spiritual approaches. Also covered are evidence-based approaches to integrative management of mood disorders in pregnant women, adolescents, and the elderly. Separating facts from fiction, the book provides practical information that clinicians can implement and share with their patients. The book fills a significant gap in the conventional model of therapeutics for mood disorders. It is a valuable resource for psychiatrists, psychologists, family therapists, and all other clinicians who devote their days to caring for those afflicted with depression.

The topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drug ability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine.

The development of more effective treatments for neuropsychiatric disorders requires scientific progress on a broad front. Animal models have a vital role to play in advancing the field. When deployed in conjunction with detailed study of these diseases in man they bring the power to make controlled experimental interventions which allow the functional consequences of genetic variations and polymorphisms to be understood in terms of their cellular, systems and behavioural effects. Further, they provide a means by which complex cognitive and behavioural phenomena may be dissected and understood. Finally, they provide a bridge to understanding the effects of drugs on the functioning of the central nervous system, thereby improving our understanding of the actions of those drugs in man.

This volume examines behavioral genetic research on temperament and personality from a number of perspectives. It takes a developmental perspective on a number of issues across the lifespan, focusing on personality and temperament. The first section focuses on the development of temperament and personality. Typically this has involved exploring genetic and environmental contributions to phenotypic stability and instability, but more recently there has been research that examines the etiology of intra-individual change/growth trajectories. The second section examines genetic and environmental contributions to the association between temperament and personality and other behaviors. The third and fourth sections discuss genotype-environment correlations and interactions, and introduces the reader to molecular genetics research on temperament and personality. Chapter 11 will discuss the significance of this type of research and Chapter 12 will provide an example of specific line of research exploring genes associated with temperament.

This title maps the emergence of a powerful psycho-social idea out of its historical and social circumstances, as the concept of injury or trauma has moved, over the 20th century, from the description of a physical, visible lesion to a more abstract, psychic harm - often thought of as an 'invisible wound'.

This book questions the notions of person, personality, dignity, and other connected notions such as (informed) consent, and discusses new perspectives on categories that allow ethical debates in medicine to overcome morals and ordinary religious schemes. The book states that one has to be careful when thinking about situations in terms of notions and principles that have been obtained in similar situations. Though this book is mostly philosophical, it is also of great practical interest to healthcare givers. It warns caregivers not to rely too much on notions such as person, autonomy, and consent, which are supposedly firm but can be proven to be unreliable in spite of appearances. Furthermore, this work warns against a narrow anthropologisation of ethics which would make technophobian positions unavoidable. On the contrary, this book is open to robotics and offers - among other things - a sustained exploration of the notion of intimacy.

Psychiatric disorders are one of the most dramatic burdens for humankind. The role of immune dysfunction in the pathophysiology of these disorders has emerged during the last years, because there has been tremendous progress in psychoneuroimmunological research. Many results are presented here by pioneers in the field. The book addresses various effects of the immune system on the pathophysiology and course of psychiatric disorders and highlights the possible future impact on treatment decisions of various psychiatric disorders, including schizophrenia and depression. The contributions cover the role of in utero immune challenges on the development of schizophrenia, the role of infections, and autoimmune diseases and mild immune activation in the development of depression and schizophrenia, the influence of immune responses in other disorders such as Tourette's, Alzheimer's, and OCD, the connections between mental and physical pain as well as between anti-inflammatory and antipsychotic drugs.

Presents examples of Mad Studies in action; initiatives that have been taken, what they have achieved and what can be learned from them Offers examples and insights from the perspectives of those who have (had) those experiences, and will also explore ways of supporting people oppressed by conventional understandings and systems. Comprised of 31 chapters written by leading experts, activists and academics

Social psychiatry is a multidisciplinary field analyzing mechanisms of mental health issues comprehensively to contribute to society using the findings. Those findings include biological, psychological, and social aspects and they are based on psychiatry and connected with a wide variety of academic fields, including psychology, sociology, law, economics, and religious studies. Epidemiological research in psychiatry is a field of study in patients with psychiatric disorder attempting to investigate causes, to develop clinical applications of the results, and to determine applications to health services plans for individuals and/or communities. They are both foundation for understanding biopsychosocial view in psychiatry but not many comprehensive volumes covering the topic were not available until now. This book is thus a unique, comprehensive reference with evidence-based approach to provide concise summary of researches for such as schizophrenia, affective disorders, psychiatric disorders in the general practice setting, and disaster psychiatry, especially for the case of atomic bomb diseases. The studies were mostly carried out in the region of Nagasaki, the prefecture experienced a nuclear attack at the time of World War . Psychiatric findings in mental health problems among atomic bomb survivors and sufferers in Nagasaki has been established and Nagasaki is the only area that fulfills the conditions of the subject of the study of psychiatric epidemiology and social psychiatry which is going to be described in this book. This book provides a valuable resource not only for physicians and researchers in the field of psychiatry and mental health but for people who work for mental health welfare department."

This unprecedented work is an invaluable resource for therapists treating patients with obsessive-compulsive personality disorder (OCPD), for individuals suffering from OCPD, and for friends, family, and coworkers of those with OCPD. Although a significant number of individuals suffer from obsessive-compulsive personality disorder (OCPD), most of these people see themselves as being perfectly normal. In actuality, they are missing out in life due to their being compulsively prompt, counterproductively perfectionistic, and excessively penurious. This book explains what OCPD is, making it clear how it differs significantly from OCD; explains the thought processes and desires that give rise to the counterproductive defense mechanisms of OCPD; and identifies the approaches and methods that can allow such afflicted individuals to break through their character armoring and become rehumanized. In this book, Martin Kantor, MD, presents information to defuse the many manifested symptoms of OCPD: anxiety, indecision, unreasonable perfectionism, and difficulty in compromising. His explanations and methods will give the hopeless succor, move the stalled forward, and foster interpersonal cooperation and flexibility in the stubborn, while simultaneously enhancing the OCPD individual's social performance thus increasing his or her chances for interpersonal, relational, and occupational success. Kantor also identifies the social manifestations of OCPD and describes how to move idiosyncratic, rigid bureaucracies toward accomplishing what should be their most important mission: helping those who are in need and seeking comfort. Explains how OCPD compromises not only the quality of life of its sufferers but also the lives of many of the people that surround each OCPD individual Examines OCPD from multiple perspectives, documenting the author's eclectic treatment approach that views OCPD from multiple vantage points, including the psychodynamic, the interpersonal, and the cognitive-behavioral Extends the discussion of OCPD to include OCPD-inspired bureaucracies and how treating these toxic environments can lead to substantially improved socioeconomic functioning worldwide Serves therapists treating patients with OCPD; patients suffering from OCPD; friends, family, and coworkers of those with OCPD; and general readers interested in mental health issues Provides a bonus section on self-help methods that can be employed by the OCPD sufferer and those in the path of OCPD fallout

Like its pioneering predecessor, this new edition of Professionalism and Ethics: Q & A Self-Study Guide for Mental Health Professionals offers an interactive, case-oriented approach to mental health ethics. Organized around scenarios that pose important-sometimes thorny-ethical questions, the book draws on the diverse clinical and research experience of its contributors, who have backgrounds in medicine, ethics, psychology, law, medical education, religious studies, public health, and related fields. The editor, an internationally recognized scholar in bioethics, psychiatry, and medical education, oversaw a rigorous review process, ensuring that the content meets the highest standard, as befits a text on ethics and professionalism. The book begins with an overview of the role of ethics in caring for people with mental illness, concepts and models of professionalism, and ethics education, followed by a chapter examining ethics in the mental health professions, with emphasis on learning and applying essential skills. Questions and annotated answers follow, and the brief case descriptions that frame each question, presented in single-answer, multiple-choice format, echo the real-life complexities of clinical practice. Psychiatry has evolved significantly since the last edition, and the new edition's plentiful revisions and fresh material reflect these changes: * Assisted suicide and euthanasia, which pose controversial and difficult ethical questions, are explored in-depth, with attention accorded religious views, the complexity of informed consent, and the concern that some who choose euthanasia may be clinically depressed.* Navigating social media, experiencing the loss of anonymity, and engaging in self-disclosure of all kinds presents new challenges for practitioners; the pitfalls, both ethical and psychological, are thoroughly discussed. * The digital age poses many ethical dilemmas regarding patient privacy. Is it acceptable for clinicians to "Google" their patients, or is it merely voyeurism? What about consent? * Burnout among mental health practitioners is growing, and professional well-being is an emergent topic. The book examines the increased expectations of physicians and what setting reasonable limits in an era of the electronic health record might look like.* Over the past few decades, neuroscience has been accepted as the conceptual basis for understanding and treating mental illness, and neuroethics have achieved an attendant importance. Human subjects research and the active question of public trust in science, as well as emerging domains, including neurotechnologies, neurolaw, and philosophy of cognition, are carefully examined. Eloquent, instructive, and pragmatic, Professionalism and Ethics: Q & A Self-Study Guide for Mental Health Professionals offers critical learning to prepare professionals for ethical challenges in care and research and is an essential reference and tool for an increasingly complex world.

What can dance movement contribute to psychotherapy?
This thoroughly updated edition of "Dance Movement Therapy "echoes the increased world-wide interest in dance movement therapy and makes a strong contribution to the emerging awareness of the nature of embodiment in psychotherapy. Recent research is incorporated, along with developments in theory and practice, to provide a comprehensive overview of this fast-growing field.
Helen Payne brings together contributions from experts in the field to offer the reader a valuable insight into the theory and practice of Dance Movement Therapy. The contributions reflect the breadth of developing approaches, covering subjects including:
- Dance movement therapy with people with dementia
- Group work with people with enduring mental health difficulties
- Transcultural competence in dance movement therapy
- Freudian thought applied to authentic movement
- Embodiment in dance movement therapy training and practice
- Personal development through dance movement therapy
"Dance Movement Therapy" will be a valuable resource for anyone who wishes to learn more about the therapeutic use of creative movement and dance. It will be welcomed by students and practitioners in the arts therapies, psychotherapy, counseling and other health and social care professions.

Why do people find it so difficult to talk openly about sex?

In this original and ground-breaking book, Morris Nitsun argues that desire and sexuality are key components of human experience that have been marginalized in the group psychotherapy literature.

Drawing on theory from psychoanalysis, developmental psychology and sociology, while keeping the group firmly in focus, he creates a picture of the potential in group therapy for the most intimate narrative. Highlighting current concerns about sexual identity, boundary transgression and what constitutes effective psychotherapy, detailed clinical illustrations cover areas such as:

• The erotic connection
• The dissociation of desire
• The group as witness
• Erotic transference and counter-transference

Psychotherapists and all those interested in sexual development and diversity will value the challenging approach to sexuality this book offers.

examines the evolutionary, psychological and social significance of fire drawing on interdisciplinary literature and original research data, it challenges the existing understanding of arson and fire setting introduces a new concept - fire use - and conceptualizes it as sitting on a continuum from non-criminalised to criminalised behavior includes a particular focus on the assessment and treatment of fire setters and a call for a socially informed approach to prevention

It has long been recognized that people with identifiable congenital causes of developmental disabilities display peculiar patterns of behavior and temperament. An explosion of new information in the field of so-called behavioral genetics has precipitated a need for a book describing behaviorial phenotypes. The book consists of three parts: Part I opens with an account of the evolution of behaviorial genetics in developmental disability. The second part covers measurement and research methodology and includes chapters on various types of self-injurious behavior that occur in different phenotypes and a chapter on Fragile X--a model for inquiry into behavioral phenotypes. The sections on genetic analysis are particularly useful to clinicians who are unfamiliar with contemporary genetic techniques. Part III summarizes behavioral phenotypes of over thirty biologically distinct conditions.