The main objective of this book is to present some of the fundamental structural aspects in the design of respiratory organs while debating and speculating on when, how and why these states were founded. The author's main thesis is that the modern gas exchangers are products of protracted processes that have entailed adaptation to specific environments and lifestyles. Only those feasible designs that have proven adequately compentent in meeting demands for molecular oxygen have been preserved. The author's approach has been to look into the limiting functional properties as regards the respiratory capacities of gas exchangers while finding out the specific structural adaptations that have evolved to meet the metabolic needs or to look into form and discern how it limits function.

"Dr. François Haas is an unusually gifted scientist and a compassionate human being."–HOWARD A. RUSK, M.D. Founder and Chairman, Rusk Institute

The bestselling guide for chronic bronchitis and emphysema sufferers–newly revised and expanded. For the millions of people diagnosed with chronic bronchitis and/or emphysema, this bestselling guide is now revised and expanded to offer the most up-to-date information available. From helping you understand your disease and its proper care to showing you how to restore vitality and satisfaction to your relationships, Dr. François Haas and Dr. Sheila Sperber Haas provide you with the facts and information needed to find the right treatment and take full advantage of it. Written in a clear and helpful style, The Chronic Bronchitis and Emphysema Handbook now includes current information on useful complementary approaches–including herbal therapy–plus effective exercises and the latest medical advances. You’ll discover:

• How to find the right doctor for you and discuss your treatment options
• How to deal with HMOs and the companies that provide supplemental oxygen
• Which new surgical techniques are most promising
• How to manage stress and anxiety
• How to slow your disease and substantially improve your quality of life
• A variety of helpful resources accessible by phone or web
• The newsletters written by experts that will keep you up-to-date

Dr. Francois Haas is an unusually gifted scientist and a compassionate human being.-HOWARD A. RUSK, M.D. Founder and Chairman, Rusk Institute
The bestselling guide for chronic bronchitis and emphysema sufferers-newly revised and expanded. For the millions of people diagnosed with chronic bronchitis and/or emphysema, this bestselling guide is now revised and expanded to offer the most up-to-date information available. From helping you understand your disease and its proper care to showing you how to restore vitality and satisfaction to your relationships, Dr. Francois Haas and Dr. Sheila Sperber Haas provide you with the facts and information needed to find the right treatment and take full advantage of it. Written in a clear and helpful style, The Chronic Bronchitis and Emphysema Handbook now includes current information on useful complementary approaches-including herbal therapy-plus effective exercises and the latest medical advances. You'll discover:
* How to find the right doctor for you and discuss your treatment options
* How to deal with HMOs and the companies that provide supplemental oxygen
* Which new surgical techniques are most promising
* How to manage stress and anxiety
* How to slow your disease and substantially improve your quality of life
* A variety of helpful resources accessible by phone or web
* The newsletters written by experts that will keep you up-to-date

Chronic obstructive pulmonary disease (COPD) is an increasingly important health problem world-wide. Whereas most other leading diseases have shown a decline in the past decades, COPD morbidity and mortality is on a steady increase. Exacerbations are usually defined as an increase in cough, a change in the colour or quantity of sputum, and a worsening dyspnea. The role of bacterial infections and the efficacy of antimicrobial therapy in acute exacerbations of chronic bronchitis (AECD) is still controversial. Exacerbations of chronic bronchitis are a common occurrence in clinical practice and are a leading cause of antibiotic prescription among respiratory infections. It is still uncertain whether each new exacerbation may deteriorate the natural history of chronic bronchitis. Undoubtedly, every episode includes a temporary worsening in lung function and may therefore pose the threat of respiratory failure or death in more severely obstructed patients.

'Brilliantly funny.' - Matt Lucas 'You have to read this book.' - Tim Harford 'It's funny, touching and gobsmacking in equal measure. At its heart is a breathtaking account of life on the COVID frontline.' - Jay Rayner 'Ed's journey is funny, sad, harrowing, hilarious... I STRONGLY URGE YOU TO READ THIS.' - Colin Mochrie 'Very Funny.' - Fern Brady 'I love your book Catch your Breath, it just feels so personal and so refreshing.' - Adil Ray, Saturday Live A gut punch of a memoir by a doctor - and comedian - whose job is to keep people alive by putting them to sleep. Ed Patrick is an anaesthetist. Strong drugs for his patients, strong coffee for him. But it's not just sleep-giving for this anaesthetist, as he navigates emergencies, patients not breathing for themselves and living with a terrifying sense of responsibility. It's enough to leave anyone feeling numb. But don't worry, there's plenty of laughing gas to be had. 'Very funny, very timely, scary in places. Ed writes with wit, insight, surprise and pathos. He is cutting his teeth in anaesthetics, taking people as close to death as you can take them, and then trying to wake them up again. And makes it funny. A joy to read.' - Phil Hammond

How does it feel to confront a pandemic from the inside, one patient at a time? To bridge the gulf between a perilously unwell patient in quarantine and their distraught family outside? To be uncertain whether the protective equipment you wear fits the science or the size of the government stockpile? To strive your utmost to maintain your humanity even while barricaded behind visors and masks? Rachel is a palliative care doctor who looked after the most gravely unwell patients on the Covid-19 wards of her hospital. Amid the tensions, fatigue and rising death toll, she witnessed the courage of patients and NHS staff alike in conditions of unprecedented adversity. For all the bleakness and fear, she found that moments that could stop you in your tracks abounded. People who rose to their best, upon facing the worst, as a microbe laid waste to the population. Her new book, Breathtaking, is an unflinching insider's account of medicine in the time of coronavirus. Drawing on testimony from nursing, acute and intensive care colleagues - as well as, crucially, her patients - Clarke argue that this age of contagion has inspired a profound attentiveness to - and gratitude for - what matters most in life.

International specialists in Microbiology, Infectious Diseases, Internal Medicine, Cardiology Immunology, Pneumonology, Neurology and Epidemiology gathered to this workshop to discuss and enhance interdisciplinary knowledge on the possible etiological role of Chlamydia pneumoniae, a widespread human respiratory infection, in the pathogenesis of chronic inflammatory diseases with major public health impact such as atherosclerosis, cardiovascular disease, adult-onset asthma bronchiale, chronic obstructive pulmonary diseases, reactive arthritis, morbus Alzheimer and multiple sclerosis. Current deficits and goals in the standardisation of diagnostic tools, basic and applied research, design of epidemiological and monitoring of therapy studies were identified. A special feature of this book is the comprehensive collection of state-of-the-art review articles in the various fields with many references.

Gastroesophageal reflux (GER) refers to symptoms and events that result from abnormal regurgitation of gastric contents into the esophagus. GER is a common clinical problem that affects large segments of the general population. The spectrum of problems associated with GER is now known to also involve extra-esophageal sites. Respiratory diseases, in particular bronchial asthma, can be exacerbated by multiple triggers, including GER. The relationship between the occurrence of gastroesophageal disorders and changes in respiratory function has been known for over a century, but the mechanism by which intraesophageal acid regurgitation can produce respiratory symptoms is still debated. The reasons for these concurrent pathological events are also not fully understood. Determining, for instance, whether reflux itself initiates or exacerbates asthma, or whether asthma or its treatment primarily causes GER is a matter of current investigation.

Management of the intensive care patient afflicted by respiratory insufficiency requires knowledge of the pathophysiological basis for altered functions. The etiology and therapy of pulmonary diseases, such as acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD) are highly complex. While physiologists and pathophysiologists work prevalently with theoretical modes, clinicians employ sophisticated ventilation support technologies in the attempt to understand the pathophysiological mechanisms of the pulmonary diseases which can present with varying grades of severity. Despite the availability of advanced technologies it is common to personalize the treatment protocol according to the patient's physiologic structure.Given the complexity and difficulties of treating respiratory disease, a strong collaboration between clinicians and physiologists is of fundamtental importance.

CLINICAL APPLICATION OF MECHANCIAL VENTILATION, FOURTH EDITION integrates fundamental concepts of respiratory physiology with the day-to-day duties of a respiratory care professional. Utilizing the wide degree of topics covered, including airway management, understanding ventilator waveforms, and addressing critical care issues, readers have the best resource available for understanding mechanical ventilation and its clinical application. Enhancing the learning experience are valuable illustrations of concepts and equipment, highlighted key points, and self-assesment questions in NRBC format with answers. Whether preparing for the national exam or double-checking a respiratory care calculation, this book provides the fundamental principles of repsiratory care with the clinical guidance necessary for mechanical ventilation.

The traditional Vienna Asthma Forum was held in early June 1996 and th was the 6 in a biennial mode within 10 years. This time it was dedicated to the long-acting beta-2-agonists, which were registered (or just about to be) in most European countries. The introduction of this therapeutic principle into routine praxis of asthma therapy was so successful that a closer view on the subject from a scientific point was warranted. Salmeterol, shortly afterwards formo- terol are the drugs available for the inhalative route, while bambuterol serves as an oral agent. The scientists particularly involved in the design and pharma- cokinetics of these drugs were invited, and we were lucky that Malcolm Johnson (Glaxo), Leif Svensson (Astra) and Gary Anderson (Ciba- Geigy) delivered fascinating contributions. However, drug therapy of this kind can only be effective if based on a thorough understanding of the molecular biology of cells and receptors, which was superbly covered by Sheila Collins (Durham) and Ian M. Adcock (London). The pediatric indications for beta-2-agonists were commented by Manfred G6tz (Vienna), and a large spectrum of clinical studies, reported by G. Boyd (Glasgow), A.P. Greening (Edinburgh), M.

Interstitial lung disease (ILD) refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It is a general category that covers many different lung conditions. Part of the Clinico Radiological Series, this book is a guide to diagnostic imaging of interstitial lung diseases for clinicians. Beginning with an overview of classification and terminology, and various imaging modalities, the following sections describe imaging techniques for many different lung disorders. A complete section is dedicated to paediatric lung diseases. The comprehensive text is highly illustrated with nearly 900 radiological images and tables. Also part of the Clinico Radiological Series, is Temporal Bone Imaging (9789385891908). Key Points Practical guide to diagnostic imaging of interstitial lung diseases Part of the Clinico Radiological Series Includes complete section on Paediatric lung diseases Highly illustrated with nearly 900 radiological images and tables

This text provides a practical introduction to peak flow measurement, its indications, uses and benefits, and associated problems.;Asthma is a very common condition affecting at least 12 per cent of schoolchildren and 5 per cent of adults. Recent guidelines proposed by the British Thoracic Society for the management of chronic and acute asthma recommend the domiciliary use of the peak flow meter to assist doctors in the management of the condition, as well as helping the patient manage his or her own asthma flow. This illustrated guide gives the doctor instructions on the correct use of the meter as well as providing information on the benefits and limitations of the test. Worked case histories and "real" examples of classical peak flow histories can be found throughout the text. It should be of use to respiratory physicians, general practitioners, practice nurses, physiotherapists and other health professionals involved in the day-to-day care of asthma patients.

A flood of data indicate the importance and the relevance in both respiratory and extrapulmonary disease of Chlamydia pneumoniae infection today. Antibody prevalence rates in Western countries reach 50% in the adult population and remain high in old age suggesting a high rate of reinfection. Chlamydia pneumoniae can cause upper respiratory tract infections, like pharyngitis and sinusitis as well as bronchitis and more than 10% of community-acquired pneumonia. Recent data suggest a possible association of Chlamydia pneumoniae infection with wheezing and adult-onset asthma. However, the most intriguing hypothesis pertains the possible association between Chlamydia pneumoniae infection and atherosclerosis.

Die strukturellen Veranderungen der Bronchialschleimhaut beim Asthma sind zwar Folge der zellularen Interaktionen, aber wesentlich trager als diese und bilden die Basis fur spater irreversible Funktionsstorungen. Daher ist die fruhe antientzundliche Therapie so wichtig. Fur diese wieder scheint das Theophyllin zunehmend interessant zu werden, wie aus neuesten in vitro und in vivo Untersuchungen hervorgeht."

The ?Understanding Asthma chart takes a look at the causes, symptoms, risk factors and treatments for asthma. The anatomy of airways and gas exchange is graphically depicted, along with a peak flow chart. Images of normal and asthmatic bronchioles are shown for comparison in the asthma attack section. Heavy gauge 3ml lamination with sealed edges and two metal eyelets for hanging makes chart highly durable. Write-on/wipe-off with dry erase marker (not included).

This book discriminates and emphasizes approaches that are likely to be productive in terms of understanding the causation and mechanisms of occupational lung diseases. It benefits research academicians in the field of lung diseases, and government and public health authorities.

Questo libro riporta lo stato dell'arte delle piu comuni malattie dell'apparato respiratorio. La prima parte e dedicata all'anatomia del polmone, alla regolazione della respirazione e alla meccanica respiratoria, seguita dall'esame funzionale del paziente respiratorio e dalla diagnostica invasiva e non invasiva, inclusa la diagnostica per immagini in pneumologia.

Nella descrizione delle malattie particolare importanza e stata data nel chiarire il "perche" dei diversi sintomi e segni clinici mentre l'approccio terapeutico, confrontato con le linee guida internazionali, fa comunque riferimento alla vasta esperienza clinica degli autori.

L'obiettivo principale di questo libro e quindi quello di riportare le piu recenti acquisizioni nella fisiologia, fisiopatologia e clinica delle malattie dell'apparato respiratorio, inclusa la ventilazione meccanica non invasiva, l'ossigenoterapia e la riabilitazione respiratoria, e di combinare una chiara descrizione della fisiopatologia respiratoria con enfasi alla sua applicazione clinica.

Il volume e rivolto sia agli studenti del corso di laurea specialistica in medicina e chirurgia, sia agli specializzandi in malattie dell'apparato respiratorio. Rappresenta inoltre un valido riferimento per il medico di medicina generale, soprattutto quando quest'ultimo intenda aumentare le proprie conoscenze cliniche, diagnostiche e terapeutiche nel settore delle patologie respiratorie, branca che sempre piu frequentemente coinvolge il medico e lo specialista nella risoluzione di casi anche molto complessi.

This book demonstrates practical and clinical applications to child management in fields such as intensive care, neonatology, diagnostic radiology and cardiothoracic and respiratory medicine. Highly illustrated, extensively referenced text is an essential guide for physiotherapitsts, nurses, students and other health professionals working with children.

This book should be of interest to general physicians, respiratory physicians, infectious diseases specialists.

Medical Semiology Guide of the Respiratory System provides a comprehensive understanding of medical semiology to facilitate the learning process and stimulate medical thinking in respiratory medicine. Highly illustrated, with many original images from the author's daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter incorporates a specific questionnaire with important questions that need to be addressed in different situations to obtain valuable information to help in medical thinking and in the formulation of a diagnosis.

Das Konzept des allergischen Asthma hat lange Zeit so sehr dominiert, daA die Immunotherapie vielfach ohne gesicherte diagnostische Grundlage, halbherzig oder ohne die Feinheiten der Allergenvermeidung angewendet wurde. Die Forschung der letzten zehn Jahre hat uns eine derartige Ausweitung unseres Wissenshorizontes beschert, daA es an der Zeit schien, maAgebliche Autoren zur gemeinsamen Diskussion der neuen Aspekte einzuladen. Das Buch berichtet von den neuesten Erkenntnissen A1/4ber zellulAres Verhalten, unterschiedliche Zytokinmuster und autoimmunologische Aspekte bis hin zur modernen Allergenvermeidung, aber auch von der wirksamen medikamentAsen Therapie der eosinophilen EntzA1/4ndung The concept of asthma being an "allergic disorder only" has dominated above others to an extent, that a re-evaluation of this issue in the light of very recent results from research in immunopathology seemed more than overdue. This volume provides a current concept of theory and clinical practice of immunopathology and therapy of asthma, comprising extensive and brand new laboratory data on atopy, intrinsic asthma, aspects of autoimmunology, as well as guidelines for allergen avoidance, immunotherapy and - last not least - pharmacological treatment of eosinophilic inflammation.

The only source to describe the lung surfactant as a complex membranous system, this guide analyzes lung surfactant function from the aspects of molecular biology, biophysics, membrane science, and surface and interface analysis and reviews the latest basic and clinical issues relating to lung disease and (dys)function.

Updated to reflect the latest scientific advances and technologies in the diagnosis and treatment of pleural diseases, this new Second Edition explores the structure and function of these diseases and malignancies, from tuberculosis and asbestos to pleurisy and pneumothorax. Edited by leading international authorities in pulmonary medicine, this comprehensive guide is an invaluable resource for pulmonologists, radiologists, and critical care physicians. Pleural Disease, Second Edition highlights: molecular and diagnostic approaches interventional applications, including pleural thoracentesis and closed biopsy, chest tube insertion, pleural lavage, medical thoracoscopy, and VATS biomarkers and proteomics translational medicine approaches, new treatment methodologies, and clinical manifestations various diagnostic tests and the importance of clinical evaluation in the differential diagnosis of a pleural effusion new surgical and non-surgical techniques to identify and diagnose pleural diseases, including: medical thoracoscopy, pleural lavage, intrapleural fibrinolytics, image-guided small bore catheters, video-assisted thoracoscopic surgery (VATS), pleuroperitoneal shunt, and extrapleural pneumonectomy

As our population continues to grow, more and more patients are becoming dependent on long-term ventilatory support. Therefore, the need for quality options such as home mechanical ventilation is fast becoming a necessity. Ventilatory Support For Chronic Respiratory Failure (CRF) is the first resource to authoritatively address the needs of the acute or chronic respiratory patient through the transition from the hospital to the home-care setting. This reference covers best practices in the management of CRF patients who are: clinically stable ventilator dependent in an institutional setting transitioning back to the community likely to require home-based care Covering ethical and economic management issues, as well as perspectives from renowned national and international specialists, this guide: guides clinicians through transitional care stages, from weaning in the acute care setting to long-term ventilation in the home discusses topics rarely detailed in acute care texts, such as physical therapy and secretion clearance contains a chapter focused on the special care needs of the CRF patient including nutritional concerns, pressure ulcers, pneumonia, and speech challenges