This issue of Critical Care Nursing Clinics will include articles on the following topics: Non-invasive ventilation; Modes of mechanical ventilation; Mechanical ventilation effect on heart/lung interactions; Effect of ventilation on the lungs; VAP; Liberation/weaning & Sedation/pain control; Self/unplanned extubation; Communication; recovery and rehab post ICU; Airway protection with aging; home ventilation; monitoring of the mechanical vent patient; and Dyspnea.

This issue of Clinics in Chest Medicine, Guest Edited by Pascal Chanez MD PhD, will focus on Asthma, with article topics including: Compliance ; Epidemics in asthma ; Genotypes of asthma ; diagnose and phenotype asthma ; Unbiased biomarkers in asthma ; Asthma as a chronic infectious disease ; Childhood Asthma Management ; Occupational Asthma ; Corticosteroid Treatments ; Airway Smooth Muscle ; Resolution of Inflammation ; and Immunological Therapeutic Interventions in Asthma.

This issue of Medical Clinics of North America provides the latest essential updates on COPD.? The following topics are covered: pathobiological mechanisms; genes and the disease (alpha-l-antitrypsin); the environment, phenotype, and comorbidity; the role and potential of imaging; pulmonary function and its importance; exercise in testing and therapy; patients' perception and quality of life; exacerbations, causes, prevention, and treatment; an integrated approach to the medical treatment; meducal pneumoplasty, surgical resection, or lung transplant; and smoking cessation and environmental hygiene.

This issue of Critical Care Clinics will focus on Severe Acute Respiratory DIstress Syndrome and dealing with it in the ICU. Topics will include: Challenges and Successes in ARDS Research;Mechanical ventilation with Lung Protective Strategies: What works?; Gene therapy for ALI/ARDS;High Frequency Oscillatory Ventilation in ALI/ARDS;Prone positioning therapy in ARDS;Recovery and Long-term outcome in ARDS; and Experimental models and emergeing hypotheses for ALI and ARDS

The first issue of Clinics in Chest Medicine to be published with this focus, this issue reviews bronchiectasis from numerous angles to provide comprehensive coverage on this important subject.? Epidemiology, airway defense mechanisms, pathogenesis, imaging and genetic causes of bronchiectasis are discussed.? Allergic bronchopulmonary aspergillosis is addressed, as well as non-tuberculous mycobacteria as a cause of bronchiectasis.? Authors examine how to evaluate the success of therapy for bronchiectasis (what endpoints to use) and then discuss a variety of therapy options: inhaled and systemic antibiotic treatment, chest physiotherapy, pharmacologic agents for mucous clearance, antipinflammatory therapy and macrolides.? Pulmonary resection and lung transplantation for bronchiectasis are reviewed. Recent advances in Cystic Fibrosis are also discussed.

The Year Book of Pulmonary Disease brings you abstracts of the articles that reported the year's breakthrough developments in pulmonary disease carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. Topics such as Asthma and Cystic Fibrosis, Chronic Obstructive Pulmonary Disease, Lung Cancer, Community-Acquired Pneumonia, Lung Transplantation, Sleep Disorders, and Critical Care Medicine are represented highlighting the most current and relevant articles in the field.

The third edition of the ABC of COPD provides the entire multidisciplinary team across both primary and secondary care with an up-to-date, easy to read and accessible account of this common lung disorder. Thoroughly updated by experienced clinicians dealing with patients with COPD on a regular basis, it discusses the entire breadth of the condition from epidemiology, causes, diagnosis, treatment and end of life care. This practical and highly visual guide contains new and extensively updated chapters on diagnosis, smoking cessation and interventional approaches as well as expanded content on non-pharmacological and pharmacological management taking into account the most recent national and international guidelines. It also explores practical issues relating to COPD in terms of pulmonary rehabilitation, oxygen use, air travel, and end of life care. The ABC of COPD is an authoritative and essential guide for specialist nurses, general practitioners, physiotherapists, junior doctors, front line staff working in emergency departments, paramedics, physician associates and students of medicine and its allied disciplines.

This issue provides valuable information on the many different pulmonary concerns that arise in pregnancy. Topics include: Radiation in pregnancy, Pharmacotherapy in pregnancy and lactation; Respiratory physiology; Asthma in pregnancy; Cystic Fibrosis in pregnancy, Pulmonary embolism in pregnancy; Interstitial lung disease and connective tissue diseases in pregnancy; Pulmonary hypertension in pregnancy; Tuberculosis in pregnancy; Pneumonia in pregnancy; Sleep in pregnancy; Smoking and smoking cessation in pregnancy; High altitude and pregnancy; Fetal oxygenation and ventilation.

Respiratory infections are among the most common causes of morbidity and mortality worldwide.? These infections present a special challenge to physicians for several reasons, including of the recent disasters caused by severe acute respiratory syndrome (SARS) and bird and swine influenza, the increase in viral and bacterial resistance to currently available anti-microbial drugs, the increased frequency of new viral lung infections in clinical practice, and the worldwide emergence of deadly drug-resistant forms of TB.? For these reasons, it is important for infectious disease specialists to have an overview of emerging respiratory infections.

This issue, Guest Edited by Drs. Shyam Mohapatra and Gary Hellermann, will include topics such as: Virus-induced airway injury and asthma inception; Pediatric infectious diseases and asthma; Rhinoviruses and inception or exacerbation of asthma; Respiratory syncytial virus infections in the adult asthmatic-role of viral subversion and host susceptibility in RSV infection; New rhinovirus clades and their significance in asthma exacerbation and airway remodeling; Metapneumovirus and asthma.

Venous Thromboembolism, a critical area for all pulmonary medicine specialists, is completely reviewed and updated in this issue, which starts with an epidemiological overview and then provides an in-depth look at the following topics: use of clinical probability algorithms (Geneva Score, Wells Criteria, and others), imaging techniques, deep vein thrombosis prophylaxis, chronic thromboembolic pulmonary hypertension, inherted hypercoaguable states, venous thromboembolism and pregnancy, interventional therapies (such as fragmentation, IVC filters, and surgical embolectomy), massive pumonary embolism and the role of thrombolysis, and upper extremity DVT.

This issue brilliantly pairs a rheumatologist with a pulmonologist to explore each of the 14 article topics.? Topics include autoantibody testing, ultility of bronchoalveolar lavage in autoimmune disease, and pulmonary manifestations of such conditions as scleroderma, rheumatoid arthritis, lupus erythematosus, Sjogren's Syndrome, Inflammatory Myopathies, and Relapsing Polychondritis.? The pulmonary vasculitities are discussed, as is antiphospholipid antibody syndrome, ankylosing spondylitis, and the impact of osteoporosis on pulmonary fuction.? Toxicity and monitoring of immunosuppressive therapy used in systemic autoimmune diseases is reviewed, as is lung transplantation in autoimmune diseases.

This book presents the current trends and state of the art solutions addressing various issues related to pulmonary disorders. Diagnostic and therapeutic challenges are tackled, starting with the noncommunicable diseases of sarcoidosis and granulomatosis with polyangiitis. Pulmonary involvement, practically unavoidable, runs an insidious course, and is often occulted by systemic symptoms. The establishment of a firm diagnosis, with a precision no one could oppugn, is difficult. Other issues pertain to quality of life, disease preventive measures, and the move toward personal health care in chronic sufferers from multiple conditions in later life. There is also an update on the prevalence and diagnostic and treatment challenges of extrapulmonary tuberculosis. In addition, the place of neuroproteomics in modern clinical practice is presented. The practical insights emphasize the role of science in advancing biomedical knowledge and care. The book is addressed to researchers and practitioners, and allied health care professionals engaged in effective patient care and therapy.

Topics include: Bronchoscopy of the past and the Future, Flexible Bronchoscopes of the 21st Century, Electromagnetic Navigation, Airway Stents, Early Diagnosis of Lung Cancer, Endoscopic Staging of Bronchogenic Carcinoma, Role of Bronchoscopy in the evaluation of Solitary Pulmonary Nodule, Endoscopic Management of Emphysema, Bronchoscopic Thermoplasty, Radiofrequency Ablation of the Peripheral Lung Lesions, Role of Bronchoscopy in Lung Transplantation, Virtual Mapping, Current Status of Pleuroscopy.

This issue offers a valuable update in the fast-moving specialty of sleep medicine.? Topics covered include: The Neurobiology of Sleep; Adult Obstructive Sleep Apnea; Central Sleep Apnea (including complex sleep apnea and ASV); Pediatric Sleep-Related Breathing Disorders; Hypoventilation Syndromes; Metabolism in OSA; Cardiovascular Consequences of Sleep Apnea; Home Sleep Apnea Testing; Insomnia; Excessive Sleepiness; Narcolepsy; Restless Leg Syndrome and Movement Disorders; Parasomnia; Circadian Rhythm Sleep Disorders; Medication Effects on Sleep; and Polysomnography.

This issue, guest edited by Alimuddin Zumla and H. Simon Schaaf, focuses on the topic of Tuberculosis. Articles include: Global Burden and Epidemiology of Tuberculosis; Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in the West. Europe and the United States: Epidemiology, Surveillance, and Control; Multidrug- and Extensively Drug-resistant Tuberculosis in Africa and South America: Epidemiology, Diagnosis and Management in Adults and Children; Antiretroviral Therapy for Control of the HIV-associated Tuberculosis Epidemic in Resource-Limited Settings; Novel and Improved Technologies for Tuberculosis Diagnosis: Progress and Challenges; Advances in Imaging Chest Tuberculosis: Blurring of Differences Between Children and Adults; Update on Tuberculosis of the Central Nervous System: Pathogenesis, Diagnosis, and Treatment; Advances in Immunotherapy for Tuberculosis Treatment, and more!

This issue will focus on treatments for Chronic Rhinosinusitis. Dr. Wyste Fokkens guest edits topics such as: "Inflammatory mechanisms in chronic rhinosinusitis with or without nasal polyposis," "European versus Asian Chronic rhinosinusitis. What did it teach us and what do we want to know," "Epithelium, cilia and mucus, their importance in chronic rhinosinusitis Noam Cohen Noam," "Aspirin intolerance: does desensitization alter the course of the disease," "Anti-inflammatory effects of macrolides: applications in CRS," and more!

Topics include: The History of Polysomnography and Sleep Technology, Generating a Signal: Biopotentials, Amplifiers and Filters, Recording sleep; Electrodes, 10/20 Recording system and sleep system specifications, Staging sleep, Respiratory monitoring equipment and detection of respiratory events, Differentiating Nocturnal Movements; Leg movements, Parasomnias and Seizures, Cardiac monitoring during sleep, Determination of Sleepiness - MWT & MSLT, Pediatric Polysomnography, PSG features of medical and psychiatric disorders and their treatments, Artifacts and Troubleshooting, Portable Monitoring, PAP titration, The Future of Sleep and Circadian Testing

This issue of Clinics in Laboratory Medicine, entitled Respiratory Viruses in Pediatric and adult Populations, is Guest Edited by Alexander J. McAdam MD, PhD, and includes: Developments in Specimen Collection and Tissue Culture for Respiratory Viruses; Nucleic acid amplification assays for respiratory viruses; Emerging molecular assays for respiratory viruses; Drug Resistance in Influenza Virus; Quantitative assays for adenovirus; RSV vaccine development; Human Metapneumovirus; and Recently discovered coronaviruses.

Topics include: The Obesity Epidemic, Altered Resting and Exercise Respiratory Physiology in Obesity, Association of Asthma and Other Obstructive Lung Diseases and Obesity, Role of Obesity in Obstructive Sleep Apnea, The Pickwickian Syndrome - Obesity Hypoventilation Syndrome, Obesity and Thromboembolic Disease, Medical Therapy of Obesity, Obesity and Bariatric Surgery, Airway Management of Patients with Obesity, Anesthetic Management of Patients with Obesity, Obesity and Acute Lung Injury, Obese Patients in the Intensive Care Units, Obesity Cardiomyopathy, Obesity and Respiratory Diseases in Childhood, Obesity and Respiratory Diseases in the Aging Population.

This issue provides an update on some of the most common conditions that a pulmonologist sees in the ICU. Topics covered include intraabdominal hypertension, liver failure, intracranial catastrophes, critical issues in Nephrology, Heart failure, adrenal insufficiency and septic shock, obstetrical emergencies in critical care, hematologic issues in the ICU, ICU cognitive outcomes, end-of-life issues, sepsis, sedation and analgesia, measurement of quality and assurance of safety, and critical care of the hematopoetic transplant recipient.

In this imporatant update, the guest editors have brought together experts in fungal disease to discuss some of the most important topics in this area: histoplasmosis, blastomycosis, coccidioidomycosis, PCP, cryptococcosis, fungal infections in the era of biologics, Candida in the ICU, Aspergillus pulmonary syndromes, fungal disease in BMT and SOT, fungal complications of lung transplantation, Moulds, serology and Ag testing, role of BAL in rapid diagnosis, molecular testing, and overview of antifungal agents.

This book reviews and discusses the differential diagnoses for the common sleep related complaints encountered in sleep and primary care clinics. It meets the market need for a book that covers differential diagnosis in sleep medicine, and does so in a comprehensive manner. Organized into two sections by age demographic, adult and pediatric, clinical case studies are presented with medications, treatments, diagnoses, and patient medical histories. Specified sleep disorders examined include insomnia, nocturnal awakenings, restless sleeping, nightmares, and sleep apnea. Additionally, chapters include medical questionnaires created for patients in clinical scenarios to aid in learning. Unique and pedagogic, Sleep Disorders is written for physicians who practice in all primary care settings and as well as those sleep physicians in training.

This issue of Pediatric Clinics, guest edited by Dr. Anne Chang, reviews the topic of Common Respiratory Disorders of Childhood. The articles in this issue approach the topic from an evidence-based management perspective. The first half of the issue offers symptom-based articles addressing respiratory noises, cough, exercise intolerance/dyspnoea, chest pain and chest wall deformity, and recurrent upper and lower respiratory infections. The second half of the issue offers disease-based articles on topics including upper respiratory tract infections and ear infections, asthma, bronchiolitis and croup, congenital airway lesions and lung disease, bronchiectasis and cystic fibrosis, aspiration lung disease, pneumonia and other respiratory infections, sleep disorders, neuromuscular disease and other chronic respiratory failure, and children on ambulatory oxygen.